- LightOn Optical Processing Unit: Scaling-up AI and HPC with a Non von Neumann co-processor We introduce LightOn's Optical Processing Unit (OPU), the first photonic AI accelerator chip available on the market for at-scale Non von Neumann computations, reaching 1500 TeraOPS. It relies on a combination of free-space optics with off-the-shelf components, together with a software API allowing a seamless integration within Python-based processing pipelines. We discuss a variety of use cases and hybrid network architectures, with the OPU used in combination of CPU/GPU, and draw a pathway towards "optical advantage". 17 authors · Jul 25, 2021
- ROPUST: Improving Robustness through Fine-tuning with Photonic Processors and Synthetic Gradients Robustness to adversarial attacks is typically obtained through expensive adversarial training with Projected Gradient Descent. Here we introduce ROPUST, a remarkably simple and efficient method to leverage robust pre-trained models and further increase their robustness, at no cost in natural accuracy. Our technique relies on the use of an Optical Processing Unit (OPU), a photonic co-processor, and a fine-tuning step performed with Direct Feedback Alignment, a synthetic gradient training scheme. We test our method on nine different models against four attacks in RobustBench, consistently improving over state-of-the-art performance. We perform an ablation study on the single components of our defense, showing that robustness arises from parameter obfuscation and the alternative training method. We also introduce phase retrieval attacks, specifically designed to increase the threat level of attackers against our own defense. We show that even with state-of-the-art phase retrieval techniques, ROPUST remains an effective defense. 5 authors · Jul 6, 2021
- Photonic Differential Privacy with Direct Feedback Alignment Optical Processing Units (OPUs) -- low-power photonic chips dedicated to large scale random projections -- have been used in previous work to train deep neural networks using Direct Feedback Alignment (DFA), an effective alternative to backpropagation. Here, we demonstrate how to leverage the intrinsic noise of optical random projections to build a differentially private DFA mechanism, making OPUs a solution of choice to provide a private-by-design training. We provide a theoretical analysis of our adaptive privacy mechanism, carefully measuring how the noise of optical random projections propagates in the process and gives rise to provable Differential Privacy. Finally, we conduct experiments demonstrating the ability of our learning procedure to achieve solid end-task performance. 7 authors · Jun 7, 2021
- OCTolyzer: Fully automatic toolkit for segmentation and feature extracting in optical coherence tomography and scanning laser ophthalmoscopy data Optical coherence tomography (OCT) and scanning laser ophthalmoscopy (SLO) of the eye has become essential to ophthalmology and the emerging field of oculomics, thus requiring a need for transparent, reproducible, and rapid analysis of this data for clinical research and the wider research community. Here, we introduce OCTolyzer, the first open-source toolkit for retinochoroidal analysis in OCT/SLO data. It features two analysis suites for OCT and SLO data, facilitating deep learning-based anatomical segmentation and feature extraction of the cross-sectional retinal and choroidal layers and en face retinal vessels. We describe OCTolyzer and evaluate the reproducibility of its OCT choroid analysis. At the population level, metrics for choroid region thickness were highly reproducible, with a mean absolute error (MAE)/Pearson correlation for macular volume choroid thickness (CT) of 6.7mum/0.99, macular B-scan CT of 11.6mum/0.99, and peripapillary CT of 5.0mum/0.99. Macular choroid vascular index (CVI) also showed strong reproducibility, with MAE/Pearson for volume CVI yielding 0.0271/0.97 and B-scan CVI 0.0130/0.91. At the eye level, measurement noise for regional and vessel metrics was below 5% and 20% of the population's variability, respectively. Outliers were caused by poor-quality B-scans with thick choroids and invisible choroid-sclera boundary. Processing times on a laptop CPU were under three seconds for macular/peripapillary B-scans and 85 seconds for volume scans. OCTolyzer can convert OCT/SLO data into reproducible and clinically meaningful retinochoroidal features and will improve the standardisation of ocular measurements in OCT/SLO image analysis, requiring no specialised training or proprietary software to be used. OCTolyzer is freely available here: https://github.com/jaburke166/OCTolyzer. 12 authors · Jul 19, 2024
11 A Preliminary Study for GPT-4o on Image Restoration OpenAI's GPT-4o model, integrating multi-modal inputs and outputs within an autoregressive architecture, has demonstrated unprecedented performance in image generation. In this work, we investigate its potential impact on the image restoration community. We present the first systematic evaluation of GPT-4o across diverse restoration tasks. Our experiments reveal that, although restoration outputs from GPT-4o are visually appealing, they often suffer from pixel-level structural fidelity when compared to ground-truth images. Common issues are variations in image proportions, shifts in object positions and quantities, and changes in viewpoint.To address it, taking image dehazing, derainning, and low-light enhancement as representative case studies, we show that GPT-4o's outputs can serve as powerful visual priors, substantially enhancing the performance of existing dehazing networks. It offers practical guidelines and a baseline framework to facilitate the integration of GPT-4o into future image restoration pipelines. We hope the study on GPT-4o image restoration will accelerate innovation in the broader field of image generation areas. To support further research, we will release GPT-4o-restored images from over 10 widely used image restoration datasets. 4 authors · May 8, 2025 2
- MS-Occ: Multi-Stage LiDAR-Camera Fusion for 3D Semantic Occupancy Prediction Accurate 3D semantic occupancy perception is essential for autonomous driving in complex environments with diverse and irregular objects. While vision-centric methods suffer from geometric inaccuracies, LiDAR-based approaches often lack rich semantic information. To address these limitations, MS-Occ, a novel multi-stage LiDAR-camera fusion framework which includes middle-stage fusion and late-stage fusion, is proposed, integrating LiDAR's geometric fidelity with camera-based semantic richness via hierarchical cross-modal fusion. The framework introduces innovations at two critical stages: (1) In the middle-stage feature fusion, the Gaussian-Geo module leverages Gaussian kernel rendering on sparse LiDAR depth maps to enhance 2D image features with dense geometric priors, and the Semantic-Aware module enriches LiDAR voxels with semantic context via deformable cross-attention; (2) In the late-stage voxel fusion, the Adaptive Fusion (AF) module dynamically balances voxel features across modalities, while the High Classification Confidence Voxel Fusion (HCCVF) module resolves semantic inconsistencies using self-attention-based refinement. Experiments on the nuScenes-OpenOccupancy benchmark show that MS-Occ achieves an Intersection over Union (IoU) of 32.1% and a mean IoU (mIoU) of 25.3%, surpassing the state-of-the-art by +0.7% IoU and +2.4% mIoU. Ablation studies further validate the contribution of each module, with substantial improvements in small-object perception, demonstrating the practical value of MS-Occ for safety-critical autonomous driving scenarios. 7 authors · Apr 22, 2025
1 Ophora: A Large-Scale Data-Driven Text-Guided Ophthalmic Surgical Video Generation Model In ophthalmic surgery, developing an AI system capable of interpreting surgical videos and predicting subsequent operations requires numerous ophthalmic surgical videos with high-quality annotations, which are difficult to collect due to privacy concerns and labor consumption. Text-guided video generation (T2V) emerges as a promising solution to overcome this issue by generating ophthalmic surgical videos based on surgeon instructions. In this paper, we present Ophora, a pioneering model that can generate ophthalmic surgical videos following natural language instructions. To construct Ophora, we first propose a Comprehensive Data Curation pipeline to convert narrative ophthalmic surgical videos into a large-scale, high-quality dataset comprising over 160K video-instruction pairs, Ophora-160K. Then, we propose a Progressive Video-Instruction Tuning scheme to transfer rich spatial-temporal knowledge from a T2V model pre-trained on natural video-text datasets for privacy-preserved ophthalmic surgical video generation based on Ophora-160K. Experiments on video quality evaluation via quantitative analysis and ophthalmologist feedback demonstrate that Ophora can generate realistic and reliable ophthalmic surgical videos based on surgeon instructions. We also validate the capability of Ophora for empowering downstream tasks of ophthalmic surgical workflow understanding. Code is available at https://github.com/mar-cry/Ophora. General Medical AI · May 12, 2025
- Practical considerations for high-fidelity wavefront shaping experiments Wavefront shaping is a technique for directing light through turbid media. The theoretical aspects of wavefront shaping are well understood, and under near-ideal experimental conditions, accurate predictions for the expected signal enhancement can be given. In practice, however, there are many experimental factors that negatively affect the outcome of the experiment. Here, we present a comprehensive overview of these experimental factors, including the effect of sample scattering properties, noise, and response of the spatial light modulator. We present simple means to identify experimental imperfections and to minimize their negative effect on the outcome of the experiment. This paper is accompanied by Python code for automatically quantifying experimental problems using the OpenWFS framework for running and simulating wavefront shaping experiments. 3 authors · Mar 22, 2024
- Deep Learning with Coherent Nanophotonic Circuits Artificial Neural Networks are computational network models inspired by signal processing in the brain. These models have dramatically improved the performance of many learning tasks, including speech and object recognition. However, today's computing hardware is inefficient at implementing neural networks, in large part because much of it was designed for von Neumann computing schemes. Significant effort has been made to develop electronic architectures tuned to implement artificial neural networks that improve upon both computational speed and energy efficiency. Here, we propose a new architecture for a fully-optical neural network that, using unique advantages of optics, promises a computational speed enhancement of at least two orders of magnitude over the state-of-the-art and three orders of magnitude in power efficiency for conventional learning tasks. We experimentally demonstrate essential parts of our architecture using a programmable nanophotonic processor. 11 authors · Oct 7, 2016
53 OpenGPT-4o-Image: A Comprehensive Dataset for Advanced Image Generation and Editing The performance of unified multimodal models for image generation and editing is fundamentally constrained by the quality and comprehensiveness of their training data. While existing datasets have covered basic tasks like style transfer and simple object manipulation, they often lack the systematic structure and challenging scenarios required for real-world applications. To address this bottleneck, we introduce OpenGPT-4o-Image, a large-scale dataset constructed using a novel methodology that combines hierarchical task taxonomy with automated data generation. Our taxonomy not only includes fundamental capabilities such as text rendering and style control but also introduces highly practical yet challenging categories like scientific imagery for chemistry illustrations and complex instruction editing requiring simultaneous execution of multiple operations. Through an automated pipeline leveraging structured resource pools and GPT-4o, we generate 80k high-quality instruction-image pairs with controlled diversity, covering 11 major domains and 51 subtasks. Extensive experiments show that fine-tuning leading models on our dataset achieves significant performance gains across multiple benchmarks, with improvements of up to 18\% on editing tasks (UniWorld-V1 on ImgEdit-Bench) and 13% on generation tasks (Harmon on GenEval). Our work demonstrates that systematic data construction is key to advancing multimodal AI capabilities. 12 authors · Sep 29, 2025 2
1 Parallelizing Optical Flow Estimation on an Ultra-Low Power RISC-V Cluster for Nano-UAV Navigation Optical flow estimation is crucial for autonomous navigation and localization of unmanned aerial vehicles (UAV). On micro and nano UAVs, real-time calculation of the optical flow is run on low power and resource-constrained microcontroller units (MCUs). Thus, lightweight algorithms for optical flow have been proposed targeting real-time execution on traditional single-core MCUs. This paper introduces an efficient parallelization strategy for optical flow computation targeting new-generation multicore low power RISC-V based microcontroller units. Our approach enables higher frame rates at lower clock speeds. It has been implemented and evaluated on the eight-core cluster of a commercial octa-core MCU (GAP8) reaching a parallelization speedup factor of 7.21 allowing for a frame rate of 500 frames per second when running on a 50 MHz clock frequency. The proposed parallel algorithm significantly boosts the camera frame rate on micro unmanned aerial vehicles, which enables higher flight speeds: the maximum flight speed can be doubled, while using less than a third of the clock frequency of previous single-core implementations. 3 authors · May 22, 2023
- OPDMulti: Openable Part Detection for Multiple Objects Openable part detection is the task of detecting the openable parts of an object in a single-view image, and predicting corresponding motion parameters. Prior work investigated the unrealistic setting where all input images only contain a single openable object. We generalize this task to scenes with multiple objects each potentially possessing openable parts, and create a corresponding dataset based on real-world scenes. We then address this more challenging scenario with OPDFormer: a part-aware transformer architecture. Our experiments show that the OPDFormer architecture significantly outperforms prior work. The more realistic multiple-object scenarios we investigated remain challenging for all methods, indicating opportunities for future work. 4 authors · Mar 24, 2023
- Light-in-the-loop: using a photonics co-processor for scalable training of neural networks As neural networks grow larger and more complex and data-hungry, training costs are skyrocketing. Especially when lifelong learning is necessary, such as in recommender systems or self-driving cars, this might soon become unsustainable. In this study, we present the first optical co-processor able to accelerate the training phase of digitally-implemented neural networks. We rely on direct feedback alignment as an alternative to backpropagation, and perform the error projection step optically. Leveraging the optical random projections delivered by our co-processor, we demonstrate its use to train a neural network for handwritten digits recognition. 7 authors · Jun 2, 2020
33 Open-Sora Plan: Open-Source Large Video Generation Model We introduce Open-Sora Plan, an open-source project that aims to contribute a large generation model for generating desired high-resolution videos with long durations based on various user inputs. Our project comprises multiple components for the entire video generation process, including a Wavelet-Flow Variational Autoencoder, a Joint Image-Video Skiparse Denoiser, and various condition controllers. Moreover, many assistant strategies for efficient training and inference are designed, and a multi-dimensional data curation pipeline is proposed for obtaining desired high-quality data. Benefiting from efficient thoughts, our Open-Sora Plan achieves impressive video generation results in both qualitative and quantitative evaluations. We hope our careful design and practical experience can inspire the video generation research community. All our codes and model weights are publicly available at https://github.com/PKU-YuanGroup/Open-Sora-Plan. 24 authors · Nov 28, 2024 2
- Accelerator-aware Neural Network Design using AutoML While neural network hardware accelerators provide a substantial amount of raw compute throughput, the models deployed on them must be co-designed for the underlying hardware architecture to obtain the optimal system performance. We present a class of computer vision models designed using hardware-aware neural architecture search and customized to run on the Edge TPU, Google's neural network hardware accelerator for low-power, edge devices. For the Edge TPU in Coral devices, these models enable real-time image classification performance while achieving accuracy typically seen only with larger, compute-heavy models running in data centers. On Pixel 4's Edge TPU, these models improve the accuracy-latency tradeoff over existing SoTA mobile models. 2 authors · Mar 5, 2020
- Harvard Glaucoma Detection and Progression: A Multimodal Multitask Dataset and Generalization-Reinforced Semi-Supervised Learning Glaucoma is the number one cause of irreversible blindness globally. A major challenge for accurate glaucoma detection and progression forecasting is the bottleneck of limited labeled patients with the state-of-the-art (SOTA) 3D retinal imaging data of optical coherence tomography (OCT). To address the data scarcity issue, this paper proposes two solutions. First, we develop a novel generalization-reinforced semi-supervised learning (SSL) model called pseudo supervisor to optimally utilize unlabeled data. Compared with SOTA models, the proposed pseudo supervisor optimizes the policy of predicting pseudo labels with unlabeled samples to improve empirical generalization. Our pseudo supervisor model is evaluated with two clinical tasks consisting of glaucoma detection and progression forecasting. The progression forecasting task is evaluated both unimodally and multimodally. Our pseudo supervisor model demonstrates superior performance than SOTA SSL comparison models. Moreover, our model also achieves the best results on the publicly available LAG fundus dataset. Second, we introduce the Harvard Glaucoma Detection and Progression (Harvard-GDP) Dataset, a multimodal multitask dataset that includes data from 1,000 patients with OCT imaging data, as well as labels for glaucoma detection and progression. This is the largest glaucoma detection dataset with 3D OCT imaging data and the first glaucoma progression forecasting dataset that is publicly available. Detailed sex and racial analysis are provided, which can be used by interested researchers for fairness learning studies. Our released dataset is benchmarked with several SOTA supervised CNN and transformer deep learning models. The dataset and code are made publicly available via https://ophai.hms.harvard.edu/datasets/harvard-gdp1000. 5 authors · Aug 25, 2023
- Simple Baselines for Image Restoration Although there have been significant advances in the field of image restoration recently, the system complexity of the state-of-the-art (SOTA) methods is increasing as well, which may hinder the convenient analysis and comparison of methods. In this paper, we propose a simple baseline that exceeds the SOTA methods and is computationally efficient. To further simplify the baseline, we reveal that the nonlinear activation functions, e.g. Sigmoid, ReLU, GELU, Softmax, etc. are not necessary: they could be replaced by multiplication or removed. Thus, we derive a Nonlinear Activation Free Network, namely NAFNet, from the baseline. SOTA results are achieved on various challenging benchmarks, e.g. 33.69 dB PSNR on GoPro (for image deblurring), exceeding the previous SOTA 0.38 dB with only 8.4% of its computational costs; 40.30 dB PSNR on SIDD (for image denoising), exceeding the previous SOTA 0.28 dB with less than half of its computational costs. The code and the pre-trained models are released at https://github.com/megvii-research/NAFNet. 4 authors · Apr 10, 2022