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Sep 11

A Survey of Scientific Large Language Models: From Data Foundations to Agent Frontiers

Scientific Large Language Models (Sci-LLMs) are transforming how knowledge is represented, integrated, and applied in scientific research, yet their progress is shaped by the complex nature of scientific data. This survey presents a comprehensive, data-centric synthesis that reframes the development of Sci-LLMs as a co-evolution between models and their underlying data substrate. We formulate a unified taxonomy of scientific data and a hierarchical model of scientific knowledge, emphasizing the multimodal, cross-scale, and domain-specific challenges that differentiate scientific corpora from general natural language processing datasets. We systematically review recent Sci-LLMs, from general-purpose foundations to specialized models across diverse scientific disciplines, alongside an extensive analysis of over 270 pre-/post-training datasets, showing why Sci-LLMs pose distinct demands -- heterogeneous, multi-scale, uncertainty-laden corpora that require representations preserving domain invariance and enabling cross-modal reasoning. On evaluation, we examine over 190 benchmark datasets and trace a shift from static exams toward process- and discovery-oriented assessments with advanced evaluation protocols. These data-centric analyses highlight persistent issues in scientific data development and discuss emerging solutions involving semi-automated annotation pipelines and expert validation. Finally, we outline a paradigm shift toward closed-loop systems where autonomous agents based on Sci-LLMs actively experiment, validate, and contribute to a living, evolving knowledge base. Collectively, this work provides a roadmap for building trustworthy, continually evolving artificial intelligence (AI) systems that function as a true partner in accelerating scientific discovery.

SVBench: A Benchmark with Temporal Multi-Turn Dialogues for Streaming Video Understanding

Despite the significant advancements of Large Vision-Language Models (LVLMs) on established benchmarks, there remains a notable gap in suitable evaluation regarding their applicability in the emerging domain of long-context streaming video understanding. Current benchmarks for video understanding typically emphasize isolated single-instance text inputs and fail to evaluate the capacity to sustain temporal reasoning throughout the entire duration of video streams. To address these limitations, we introduce SVBench, a pioneering benchmark with temporal multi-turn question-answering chains specifically designed to thoroughly assess the capabilities of streaming video understanding of current LVLMs. We design a semi-automated annotation pipeline to obtain 49,979 Question-Answer (QA) pairs of 1,353 streaming videos, which includes generating QA chains that represent a series of consecutive multi-turn dialogues over video segments and constructing temporal linkages between successive QA chains. Our experimental results, obtained from 14 models in dialogue and streaming evaluations, reveal that while the closed-source GPT-4o outperforms others, most open-source LVLMs struggle with long-context streaming video understanding. We also construct a StreamingChat model, which significantly outperforms open-source LVLMs on our SVBench and achieves comparable performance on diverse vision-language benchmarks. We expect SVBench to advance the research of streaming video understanding by providing a comprehensive and in-depth analysis of current LVLMs. Our benchmark and model can be accessed at https://yzy-bupt.github.io/SVBench.

VLDBench: Vision Language Models Disinformation Detection Benchmark

The rapid rise of AI-generated content has made detecting disinformation increasingly challenging. In particular, multimodal disinformation, i.e., online posts-articles that contain images and texts with fabricated information are specially designed to deceive. While existing AI safety benchmarks primarily address bias and toxicity, multimodal disinformation detection remains largely underexplored. To address this challenge, we present the Vision-Language Disinformation Detection Benchmark VLDBench, the first comprehensive benchmark for detecting disinformation across both unimodal (text-only) and multimodal (text and image) content, comprising 31,000} news article-image pairs, spanning 13 distinct categories, for robust evaluation. VLDBench features a rigorous semi-automated data curation pipeline, with 22 domain experts dedicating 300 plus hours} to annotation, achieving a strong inter-annotator agreement (Cohen kappa = 0.78). We extensively evaluate state-of-the-art Large Language Models (LLMs) and Vision-Language Models (VLMs), demonstrating that integrating textual and visual cues in multimodal news posts improves disinformation detection accuracy by 5 - 35 % compared to unimodal models. Developed in alignment with AI governance frameworks such as the EU AI Act, NIST guidelines, and the MIT AI Risk Repository 2024, VLDBench is expected to become a benchmark for detecting disinformation in online multi-modal contents. Our code and data will be publicly available.

MIRIAD: Augmenting LLMs with millions of medical query-response pairs

LLMs are bound to transform healthcare with advanced decision support and flexible chat assistants. However, LLMs are prone to generate inaccurate medical content. To ground LLMs in high-quality medical knowledge, LLMs have been equipped with external knowledge via RAG, where unstructured medical knowledge is split into small text chunks that can be selectively retrieved and integrated into the LLMs context. Yet, existing RAG pipelines rely on raw, unstructured medical text, which can be noisy, uncurated and difficult for LLMs to effectively leverage. Systematic approaches to organize medical knowledge to best surface it to LLMs are generally lacking. To address these challenges, we introduce MIRIAD, a large-scale, curated corpus of 5,821,948 medical QA pairs, each rephrased from and grounded in a passage from peer-reviewed medical literature using a semi-automated pipeline combining LLM generation, filtering, grounding, and human annotation. Unlike prior medical corpora, which rely on unstructured text, MIRIAD encapsulates web-scale medical knowledge in an operationalized query-response format, which enables more targeted retrieval. Experiments on challenging medical QA benchmarks show that augmenting LLMs with MIRIAD improves accuracy up to 6.7% compared to unstructured RAG baselines with the same source corpus and with the same amount of retrieved text. Moreover, MIRIAD improved the ability of LLMs to detect medical hallucinations by 22.5 to 37% (increase in F1 score). We further introduce MIRIAD-Atlas, an interactive map of MIRIAD spanning 56 medical disciplines, enabling clinical users to visually explore, search, and refine medical knowledge. MIRIAD promises to unlock a wealth of down-stream applications, including medical information retrievers, enhanced RAG applications, and knowledge-grounded chat interfaces, which ultimately enables more reliable LLM applications in healthcare.

VideoGPT+: Integrating Image and Video Encoders for Enhanced Video Understanding

Building on the advances of language models, Large Multimodal Models (LMMs) have contributed significant improvements in video understanding. While the current video LMMs utilize advanced Large Language Models (LLMs), they rely on either image or video encoders to process visual inputs, each of which has its own limitations. Image encoders excel at capturing rich spatial details from frame sequences but lack explicit temporal context, which can be important in videos with intricate action sequences. On the other hand, video encoders provide temporal context but are often limited by computational constraints that lead to processing only sparse frames at lower resolutions, resulting in reduced contextual and spatial understanding. To this end, we introduce VideoGPT+, which combines the complementary benefits of the image encoder (for detailed spatial understanding) and the video encoder (for global temporal context modeling). The model processes videos by dividing them into smaller segments and applies an adaptive pooling strategy on features extracted by both image and video encoders. Our architecture showcases improved performance across multiple video benchmarks, including VCGBench, MVBench and Zero-shot question-answering. Further, we develop 112K video-instruction set using a novel semi-automatic annotation pipeline which further improves the model performance. Additionally, to comprehensively evaluate video LMMs, we present VCGBench-Diverse, covering 18 broad video categories such as lifestyle, sports, science, gaming, and surveillance videos. This benchmark with 4,354 question-answer pairs evaluates the generalization of existing LMMs on dense video captioning, spatial and temporal understanding, and complex reasoning, ensuring comprehensive assessment across diverse video types and dynamics. Code: https://github.com/mbzuai-oryx/VideoGPT-plus.