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---
library_name: popV
license: cc-by-4.0
tags:
- biology
- genomics
- single-cell
- anndata_version:0.11.3
- python_version:3.11.12
- popV
- 'tissue: diverse'
---
Popular Vote (popV) model for automated cell type annotation of single-cell RNA-seq data. We provide here pretrained models
for plug-in use in your own analysis.
Follow our [tutorial](https://github.com/YosefLab/popV/blob/main/tabula_sapiens_tutorial.ipynb) to learn how to use the model for cell type annotation.
# Model description
Ageing is characterized by a progressive loss of physiological integrity, leading to impaired function and increased vulnerability to death. Despite rapid advances over recent years, many of the molecular and cellular processes that underlie the progressive loss of healthy physiology are poorly understood. To gain a better insight into these processes, here we generate a single-cell transcriptomic atlas across the lifespan of Mus musculus that includes data from 23 tissues and organs. We found cell-specific changes occurring across multiple cell types and organs, as well as age-related changes in the cellular composition of different organs. Using single-cell transcriptomic data, we assessed cell-type-specific manifestations of different hallmarks of ageing—such as senescence, genomic instability and changes in the immune system. This transcriptomic atlas—which we denote Tabula Muris Senis, or ‘Mouse Ageing Cell Atlas’—provides molecular information about how the most important hallmarks of ageing are reflected in a broad range of tissues and cell types.
**Link to CELLxGENE**:
Link to the [data](https://cellxgene.cziscience.com/e/f16a8f4d-bc97-43c5-a2f6-bbda952e4c5c.cxg/) in the CELLxGENE browser for interactive exploration of the data and download of the source data.
**Training Code URL**:
Not provided by uploader.
# Metrics
We provide here accuracies for each of the experts and the ensemble model. The validation set accuracies are
computed on a 10% random subset of the data that was not used for training.
| Cell Type | N cells | celltypist | knn bbknn | knn harmony | knn on scvi | onclass | scanvi | svm | xgboost | Consensus Prediction |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| B cell | 3640 | 0.86 | 0.90 | 0.86 | 0.87 | 0.00 | 0.87 | 0.72 | 0.79 | 0.91 |
| mesenchymal stem cell | 1646 | 0.87 | 0.88 | 0.87 | 0.75 | 0.00 | 0.66 | 0.91 | 0.86 | 0.93 |
| basal cell of epidermis | 1572 | 0.86 | 0.87 | 0.82 | 0.87 | 0.00 | 0.83 | 0.86 | 0.83 | 0.91 |
| granulocyte | 1651 | 0.82 | 0.86 | 0.82 | 0.80 | 0.00 | 0.82 | 0.74 | 0.85 | 0.89 |
| endothelial cell | 1404 | 0.87 | 0.88 | 0.82 | 0.71 | 0.00 | 0.70 | 0.90 | 0.86 | 0.91 |
| microglial cell | 1326 | 0.99 | 0.99 | 0.95 | 0.98 | 0.00 | 0.97 | 0.98 | 0.99 | 0.99 |
| T cell | 1244 | 0.78 | 0.80 | 0.66 | 0.63 | 0.00 | 0.73 | 0.65 | 0.74 | 0.81 |
| keratinocyte | 1231 | 0.85 | 0.88 | 0.80 | 0.86 | 0.00 | 0.81 | 0.88 | 0.86 | 0.91 |
| macrophage | 979 | 0.41 | 0.67 | 0.61 | 0.53 | 0.00 | 0.42 | 0.51 | 0.55 | 0.71 |
| classical monocyte | 795 | 0.81 | 0.61 | 0.62 | 0.65 | 0.00 | 0.77 | 0.80 | 0.82 | 0.90 |
| granulocytopoietic cell | 806 | 0.65 | 0.80 | 0.66 | 0.67 | 0.00 | 0.63 | 0.68 | 0.80 | 0.82 |
| bladder urothelial cell | 634 | 0.98 | 0.98 | 0.94 | 0.92 | 0.00 | 0.83 | 0.99 | 0.98 | 0.98 |
| mesenchymal stem cell of adipose tissue | 610 | 0.85 | 0.85 | 0.69 | 0.60 | 0.00 | 0.59 | 0.90 | 0.80 | 0.89 |
| fibroblast of cardiac tissue | 616 | 0.96 | 0.95 | 0.80 | 0.67 | 0.00 | 0.58 | 0.96 | 0.92 | 0.97 |
| endothelial cell of coronary artery | 583 | 0.85 | 0.88 | 0.64 | 0.50 | 0.00 | 0.37 | 0.89 | 0.85 | 0.92 |
| skeletal muscle satellite cell | 420 | 0.97 | 0.97 | 0.93 | 0.97 | 0.00 | 0.96 | 0.96 | 0.94 | 0.97 |
| proerythroblast | 442 | 0.50 | 0.53 | 0.45 | 0.26 | 0.00 | 0.62 | 0.45 | 0.65 | 0.64 |
| kidney proximal convoluted tubule epithelial cell | 436 | 0.86 | 0.87 | 0.28 | 0.81 | 0.00 | 0.75 | 0.87 | 0.87 | 0.88 |
| bronchial smooth muscle cell | 430 | 0.93 | 0.95 | 0.85 | 0.84 | 0.00 | 0.88 | 0.95 | 0.94 | 0.95 |
| myeloid cell | 440 | 0.51 | 0.62 | 0.46 | 0.51 | 0.00 | 0.38 | 0.70 | 0.67 | 0.74 |
| hepatocyte | 382 | 0.99 | 0.98 | 0.99 | 0.98 | 0.00 | 0.96 | 0.99 | 0.99 | 0.99 |
| type B pancreatic cell | 418 | 0.97 | 0.97 | 0.95 | 0.97 | 0.00 | 0.98 | 0.98 | 0.97 | 0.98 |
| bladder cell | 383 | 0.97 | 0.96 | 0.93 | 0.67 | 0.00 | 0.78 | 0.99 | 0.95 | 0.99 |
| promonocyte | 387 | 0.71 | 0.74 | 0.73 | 0.59 | 0.00 | 0.67 | 0.74 | 0.79 | 0.84 |
| DN4 thymocyte | 338 | 0.38 | 0.51 | 0.32 | 0.33 | 0.00 | 0.17 | 0.54 | 0.63 | 0.53 |
| basal cell | 360 | 0.98 | 0.97 | 0.98 | 0.95 | 0.00 | 0.92 | 0.98 | 0.96 | 0.98 |
| monocyte | 393 | 0.64 | 0.58 | 0.56 | 0.33 | 0.00 | 0.56 | 0.76 | 0.75 | 0.82 |
| enterocyte of epithelium of large intestine | 403 | 0.90 | 0.93 | 0.84 | 0.91 | 0.00 | 0.90 | 0.93 | 0.92 | 0.94 |
| thymocyte | 372 | 0.74 | 0.74 | 0.65 | 0.83 | 0.00 | 0.80 | 0.88 | 0.91 | 0.86 |
| epithelial cell of proximal tubule | 298 | 0.82 | 0.81 | 0.73 | 0.71 | 0.00 | 0.76 | 0.80 | 0.80 | 0.83 |
| natural killer cell | 330 | 0.85 | 0.85 | 0.72 | 0.74 | 0.00 | 0.79 | 0.78 | 0.83 | 0.85 |
| naive B cell | 342 | 0.46 | 0.25 | 0.55 | 0.47 | 0.00 | 0.48 | 0.49 | 0.51 | 0.61 |
| hematopoietic stem cell | 342 | 0.90 | 0.93 | 0.89 | 0.90 | 0.00 | 0.88 | 0.94 | 0.93 | 0.94 |
| mature NK T cell | 324 | 0.63 | 0.66 | 0.49 | 0.18 | 0.00 | 0.52 | 0.56 | 0.68 | 0.71 |
| fibroblast | 307 | 0.45 | 0.24 | 0.46 | 0.47 | 0.00 | 0.26 | 0.62 | 0.60 | 0.64 |
| stromal cell | 340 | 0.74 | 0.53 | 0.70 | 0.32 | 0.00 | 0.35 | 0.89 | 0.73 | 0.87 |
| keratinocyte stem cell | 301 | 0.94 | 0.92 | 0.86 | 0.90 | 0.00 | 0.85 | 0.93 | 0.91 | 0.94 |
| erythroblast | 266 | 0.65 | 0.69 | 0.68 | 0.56 | 0.00 | 0.62 | 0.69 | 0.74 | 0.80 |
| Kupffer cell | 292 | 0.97 | 0.93 | 0.73 | 0.56 | 0.00 | 0.90 | 0.97 | 0.97 | 0.98 |
| megakaryocyte-erythroid progenitor cell | 250 | 0.57 | 0.63 | 0.56 | 0.52 | 0.00 | 0.62 | 0.61 | 0.69 | 0.75 |
| pancreatic acinar cell | 280 | 0.95 | 0.93 | 0.95 | 0.97 | 0.00 | 0.98 | 0.99 | 0.97 | 0.99 |
| luminal epithelial cell of mammary gland | 261 | 0.93 | 0.93 | 0.94 | 0.79 | 0.00 | 0.89 | 0.95 | 0.93 | 0.97 |
| professional antigen presenting cell | 221 | 0.03 | 0.01 | 0.08 | 0.00 | 0.00 | 0.00 | 0.35 | 0.35 | 0.05 |
| epidermal cell | 249 | 0.87 | 0.87 | 0.81 | 0.81 | 0.00 | 0.85 | 0.89 | 0.85 | 0.90 |
| hematopoietic precursor cell | 217 | 0.64 | 0.76 | 0.42 | 0.34 | 0.00 | 0.40 | 0.69 | 0.75 | 0.82 |
| oligodendrocyte | 201 | 0.97 | 0.97 | 0.95 | 0.97 | 0.00 | 0.98 | 0.99 | 0.98 | 0.98 |
| fibroblast of lung | 188 | 0.96 | 0.96 | 0.93 | 0.92 | 0.00 | 0.95 | 0.98 | 0.95 | 0.97 |
| CD8-positive, alpha-beta T cell | 201 | 0.43 | 0.50 | 0.31 | 0.31 | 0.00 | 0.44 | 0.45 | 0.58 | 0.59 |
| epithelial cell of large intestine | 214 | 0.82 | 0.83 | 0.56 | 0.78 | 0.00 | 0.79 | 0.85 | 0.84 | 0.87 |
| intestinal crypt stem cell | 192 | 0.84 | 0.88 | 0.65 | 0.83 | 0.00 | 0.83 | 0.87 | 0.84 | 0.90 |
| chondrocyte | 185 | 0.72 | 0.62 | 0.75 | 0.63 | 0.00 | 0.73 | 0.83 | 0.78 | 0.78 |
| immature T cell | 187 | 0.72 | 0.00 | 0.13 | 0.61 | 0.00 | 0.53 | 0.83 | 0.86 | 0.72 |
| precursor B cell | 170 | 0.71 | 0.83 | 0.67 | 0.72 | 0.00 | 0.57 | 0.79 | 0.81 | 0.88 |
| intermediate monocyte | 193 | 0.23 | 0.03 | 0.31 | 0.33 | 0.00 | 0.61 | 0.53 | 0.56 | 0.65 |
| large intestine goblet cell | 171 | 0.80 | 0.85 | 0.76 | 0.79 | 0.00 | 0.83 | 0.92 | 0.86 | 0.88 |
| CD4-positive, alpha-beta T cell | 172 | 0.00 | 0.46 | 0.19 | 0.27 | 0.00 | 0.37 | 0.39 | 0.43 | 0.50 |
| smooth muscle cell | 184 | 0.64 | 0.80 | 0.73 | 0.66 | 0.00 | 0.75 | 0.86 | 0.82 | 0.78 |
| leukocyte | 167 | 0.49 | 0.57 | 0.31 | 0.31 | 0.00 | 0.27 | 0.57 | 0.64 | 0.73 |
| plasma cell | 160 | 0.51 | 0.65 | 0.53 | 0.40 | 0.00 | 0.58 | 0.52 | 0.63 | 0.67 |
| lymphocyte | 164 | 0.26 | 0.29 | 0.26 | 0.12 | 0.00 | 0.06 | 0.23 | 0.39 | 0.36 |
| naive T cell | 160 | 0.79 | 0.86 | 0.86 | 0.82 | 0.00 | 0.77 | 0.87 | 0.85 | 0.87 |
| kidney loop of Henle thick ascending limb epithelial cell | 162 | 0.91 | 0.93 | 0.67 | 0.76 | 0.00 | 0.46 | 0.92 | 0.92 | 0.96 |
| immature B cell | 126 | 0.76 | 0.73 | 0.65 | 0.73 | 0.00 | 0.68 | 0.52 | 0.60 | 0.80 |
| alveolar macrophage | 132 | 0.92 | 0.92 | 0.82 | 0.91 | 0.00 | 0.95 | 0.97 | 0.94 | 0.96 |
| endothelial cell of hepatic sinusoid | 134 | 0.97 | 0.96 | 0.95 | 0.72 | 0.00 | 0.83 | 0.97 | 0.96 | 0.98 |
| lung macrophage | 120 | 0.84 | 0.08 | 0.46 | 0.20 | 0.00 | 0.84 | 0.85 | 0.78 | 0.93 |
| non-classical monocyte | 140 | 0.59 | 0.69 | 0.58 | 0.58 | 0.00 | 0.71 | 0.80 | 0.74 | 0.77 |
| endocardial cell | 100 | 0.93 | 0.93 | 0.92 | 0.82 | 0.00 | 0.87 | 0.87 | 0.84 | 0.91 |
| double negative thymocyte | 92 | 0.62 | 0.00 | 0.26 | 0.13 | 0.00 | 0.37 | 0.69 | 0.73 | 0.75 |
| late pro-B cell | 91 | 0.71 | 0.74 | 0.46 | 0.63 | 0.00 | 0.49 | 0.54 | 0.79 | 0.83 |
| kidney collecting duct principal cell | 114 | 0.74 | 0.91 | 0.81 | 0.81 | 0.00 | 0.88 | 0.95 | 0.90 | 0.95 |
| basal epithelial cell of tracheobronchial tree | 87 | 0.91 | 0.73 | 0.84 | 0.70 | 0.00 | 0.57 | 0.89 | 0.82 | 0.95 |
| mesenchymal cell | 98 | 0.31 | 0.00 | 0.04 | 0.06 | 0.00 | 0.04 | 0.48 | 0.52 | 0.46 |
| pancreatic A cell | 84 | 0.66 | 0.72 | 0.56 | 0.77 | 0.00 | 0.85 | 0.87 | 0.86 | 0.85 |
| adventitial cell | 86 | 0.69 | 0.62 | 0.57 | 0.20 | 0.00 | 0.14 | 0.85 | 0.54 | 0.78 |
| epithelial cell | 83 | 0.41 | 0.12 | 0.58 | 0.52 | 0.00 | 0.20 | 0.52 | 0.63 | 0.67 |
| kidney distal convoluted tubule epithelial cell | 62 | 0.74 | 0.85 | 0.71 | 0.31 | 0.00 | 0.86 | 0.89 | 0.82 | 0.89 |
| neutrophil | 78 | 0.57 | 0.66 | 0.39 | 0.50 | 0.00 | 0.47 | 0.71 | 0.65 | 0.74 |
| pancreatic ductal cell | 72 | 0.92 | 0.76 | 0.83 | 0.86 | 0.00 | 0.88 | 0.94 | 0.88 | 0.92 |
| myeloid dendritic cell | 48 | 0.36 | 0.48 | 0.40 | 0.40 | 0.00 | 0.44 | 0.63 | 0.45 | 0.62 |
| astrocyte | 61 | 0.90 | 0.94 | 0.94 | 0.95 | 0.00 | 0.94 | 0.96 | 0.89 | 0.97 |
| secretory cell | 56 | 0.25 | 0.51 | 0.37 | 0.42 | 0.00 | 0.69 | 0.86 | 0.82 | 0.73 |
| myeloid leukocyte | 57 | 0.62 | 0.41 | 0.46 | 0.18 | 0.00 | 0.27 | 0.54 | 0.58 | 0.78 |
| plasmatocyte | 42 | 0.75 | 0.78 | 0.48 | 0.64 | 0.00 | 0.61 | 0.83 | 0.77 | 0.87 |
| neuron | 47 | 0.62 | 0.64 | 0.82 | 0.78 | 0.00 | 0.85 | 0.87 | 0.79 | 0.86 |
| brain pericyte | 41 | 0.44 | 0.79 | 0.57 | 0.70 | 0.00 | 0.82 | 0.93 | 0.87 | 0.83 |
| vein endothelial cell | 57 | 0.48 | 0.80 | 0.62 | 0.51 | 0.00 | 0.79 | 0.85 | 0.76 | 0.86 |
| pancreatic D cell | 39 | 0.00 | 0.56 | 0.48 | 0.86 | 0.00 | 0.88 | 0.91 | 0.93 | 0.91 |
| kidney collecting duct epithelial cell | 33 | 0.37 | 0.60 | 0.17 | 0.70 | 0.00 | 0.54 | 0.84 | 0.77 | 0.88 |
| aortic endothelial cell | 0 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| brush cell | 43 | 0.84 | 0.72 | 0.24 | 0.79 | 0.00 | 0.72 | 0.81 | 0.81 | 0.87 |
| erythroid progenitor cell, mammalian | 38 | 0.49 | 0.00 | 0.70 | 0.16 | 0.00 | 0.19 | 0.69 | 0.55 | 0.83 |
| regular atrial cardiac myocyte | 32 | 0.32 | 0.47 | 0.32 | 0.41 | 0.00 | 0.38 | 0.52 | 0.53 | 0.62 |
| kidney cortex artery cell | 42 | 0.77 | 0.85 | 0.65 | 0.26 | 0.00 | 0.32 | 0.71 | 0.61 | 0.82 |
| erythrocyte | 44 | 0.82 | 0.64 | 0.60 | 0.79 | 0.00 | 0.70 | 0.81 | 0.86 | 0.89 |
| mesangial cell | 38 | 0.00 | 0.79 | 0.45 | 0.22 | 0.00 | 0.30 | 0.78 | 0.63 | 0.80 |
| kidney loop of Henle ascending limb epithelial cell | 23 | 0.27 | 0.49 | 0.29 | 0.13 | 0.00 | 0.27 | 0.54 | 0.54 | 0.69 |
| cardiac muscle cell | 42 | 0.81 | 0.81 | 0.72 | 0.91 | 0.00 | 0.89 | 1.00 | 0.97 | 0.99 |
| mature alpha-beta T cell | 37 | 0.00 | 0.20 | 0.10 | 0.38 | 0.00 | 0.32 | 0.38 | 0.49 | 0.31 |
| basophil | 31 | 0.54 | 0.69 | 0.75 | 0.58 | 0.00 | 0.40 | 0.67 | 0.52 | 0.81 |
| cardiac valve cell | 24 | 0.63 | 0.71 | 0.48 | 0.68 | 0.00 | 0.70 | 0.82 | 0.73 | 0.77 |
| oligodendrocyte precursor cell | 38 | 0.97 | 0.97 | 0.96 | 0.97 | 0.00 | 0.96 | 0.99 | 0.99 | 0.99 |
| Schwann cell | 26 | 0.74 | 0.81 | 0.76 | 0.75 | 0.00 | 0.74 | 0.80 | 0.69 | 0.79 |
| pulmonary interstitial fibroblast | 23 | 0.92 | 0.85 | 0.81 | 0.82 | 0.00 | 0.81 | 0.90 | 0.94 | 0.96 |
| smooth muscle cell of trachea | 23 | 0.00 | 0.29 | 0.32 | 0.27 | 0.00 | 0.07 | 0.52 | 0.52 | 0.27 |
| granulocyte monocyte progenitor cell | 31 | 0.00 | 0.63 | 0.74 | 0.73 | 0.00 | 0.75 | 0.91 | 0.85 | 0.92 |
| interneuron | 22 | 0.51 | 0.59 | 0.45 | 0.68 | 0.00 | 0.76 | 0.89 | 0.75 | 0.81 |
| pancreatic PP cell | 27 | 0.00 | 0.14 | 0.20 | 0.59 | 0.00 | 0.73 | 0.75 | 0.81 | 0.58 |
| smooth muscle cell of the pulmonary artery | 20 | 0.00 | 0.62 | 0.57 | 0.40 | 0.00 | 0.33 | 0.83 | 0.77 | 0.76 |
| cell of skeletal muscle | 22 | 0.89 | 0.91 | 0.72 | 0.93 | 0.00 | 0.92 | 0.89 | 0.90 | 0.93 |
| brush cell of epithelium proper of large intestine | 15 | 0.49 | 0.70 | 0.22 | 0.81 | 0.00 | 0.67 | 0.91 | 0.88 | 0.83 |
| Langerhans cell | 22 | 0.91 | 0.86 | 0.53 | 0.66 | 0.00 | 0.48 | 0.79 | 0.83 | 0.93 |
| stem cell of epidermis | 13 | 0.00 | 0.00 | 0.42 | 0.47 | 0.00 | 0.44 | 0.59 | 0.42 | 0.76 |
| regulatory T cell | 15 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.16 | 0.17 | 0.12 | 0.00 |
| epithelial cell of thymus | 19 | 0.10 | 0.00 | 0.23 | 0.27 | 0.00 | 0.06 | 0.57 | 0.39 | 0.25 |
| enteroendocrine cell | 13 | 0.75 | 0.67 | 0.56 | 0.73 | 0.00 | 0.86 | 1.00 | 0.69 | 0.83 |
| kidney capillary endothelial cell | 16 | 0.24 | 0.45 | 0.48 | 0.07 | 0.00 | 0.34 | 0.26 | 0.28 | 0.34 |
| neuroepithelial stem cell | 21 | 0.25 | 0.31 | 0.58 | 0.52 | 0.00 | 0.33 | 0.87 | 0.58 | 0.70 |
| macrophage dendritic cell progenitor | 14 | 0.00 | 0.38 | 0.46 | 0.42 | 0.00 | 0.36 | 0.60 | 0.47 | 0.67 |
| DN3 thymocyte | 18 | 0.00 | 0.10 | 0.10 | 0.71 | 0.00 | 0.61 | 0.74 | 0.67 | 0.65 |
| regular ventricular cardiac myocyte | 6 | 0.27 | 0.00 | 0.36 | 0.40 | 0.00 | 0.71 | 0.62 | 0.57 | 0.67 |
| endothelial cell of lymphatic vessel | 6 | 0.00 | 0.40 | 0.91 | 0.17 | 0.00 | 0.16 | 0.44 | 0.35 | 0.62 |
| ciliated columnar cell of tracheobronchial tree | 8 | 0.00 | 0.76 | 0.80 | 0.89 | 0.00 | 0.40 | 1.00 | 0.93 | 1.00 |
| plasmacytoid dendritic cell | 10 | 0.00 | 0.18 | 0.50 | 0.00 | 0.00 | 0.13 | 0.55 | 0.36 | 0.67 |
| dendritic cell | 10 | 0.00 | 0.27 | 0.24 | 0.18 | 0.00 | 0.16 | 0.41 | 0.42 | 0.48 |
| medium spiny neuron | 12 | 0.00 | 0.59 | 0.80 | 0.70 | 0.00 | 0.92 | 1.00 | 0.92 | 0.96 |
| pericyte | 11 | 0.88 | 0.92 | 0.96 | 0.73 | 0.00 | 0.92 | 0.85 | 0.88 | 0.96 |
| neural stem cell | 12 | 0.29 | 0.50 | 0.70 | 0.91 | 0.00 | 0.72 | 1.00 | 0.96 | 0.96 |
| kidney proximal straight tubule epithelial cell | 9 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.26 | 0.00 |
| blood cell | 12 | 0.31 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.36 | 0.21 | 0.33 |
| immature NK T cell | 11 | 0.00 | 0.17 | 0.25 | 0.15 | 0.00 | 0.15 | 0.40 | 0.24 | 0.53 |
| cardiac neuron | 8 | 0.00 | 0.00 | 0.22 | 0.33 | 0.00 | 0.50 | 0.50 | 0.44 | 0.50 |
| mast cell | 10 | 0.00 | 0.00 | 0.40 | 0.27 | 0.00 | 0.00 | 0.56 | 0.69 | 0.50 |
| mucus secreting cell | 9 | 0.00 | 0.40 | 0.71 | 0.56 | 0.00 | 0.47 | 0.80 | 0.84 | 0.94 |
| early pro-B cell | 9 | 0.00 | 0.50 | 0.62 | 0.50 | 0.00 | 0.67 | 0.63 | 0.70 | 0.62 |
| pancreatic stellate cell | 12 | 0.80 | 0.40 | 0.50 | 0.53 | 0.00 | 0.13 | 0.56 | 0.88 | 0.86 |
| ependymal cell | 8 | 0.82 | 0.80 | 0.93 | 0.89 | 0.00 | 0.76 | 0.89 | 0.89 | 0.94 |
| Bergmann glial cell | 6 | 0.00 | 0.67 | 0.67 | 0.73 | 0.00 | 0.71 | 0.91 | 0.80 | 0.91 |
| neuroendocrine cell | 4 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.57 | 0.50 | 0.00 |
| fibrocyte | 0 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| hepatic stellate cell | 2 | 0.00 | 1.00 | 0.67 | 0.57 | 0.00 | 0.22 | 1.00 | 0.67 | 1.00 |
| club cell | 2 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| respiratory basal cell | 1 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| kidney interstitial fibroblast | 2 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.15 | 0.40 | 0.40 | 1.00 |
| lymphoid lineage restricted progenitor cell | 0 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| lung neuroendocrine cell | 0 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| kidney cell | 0 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| duct epithelial cell | 1 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 |
The train accuracies are computed on the training data.
| Cell Type | N cells | celltypist | knn bbknn | knn harmony | knn on scvi | onclass | scanvi | svm | xgboost | Consensus Prediction |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| B cell | 32688 | 0.85 | 0.90 | 0.89 | 0.93 | 0.00 | 0.93 | 0.73 | 0.79 | 0.95 |
| mesenchymal stem cell | 14492 | 0.86 | 0.86 | 0.92 | 0.89 | 0.00 | 0.91 | 0.91 | 0.85 | 0.95 |
| basal cell of epidermis | 14065 | 0.85 | 0.87 | 0.91 | 0.92 | 0.00 | 0.85 | 0.86 | 0.84 | 0.92 |
| granulocyte | 13911 | 0.80 | 0.84 | 0.90 | 0.91 | 0.00 | 0.86 | 0.74 | 0.85 | 0.91 |
| endothelial cell | 13412 | 0.86 | 0.86 | 0.87 | 0.86 | 0.00 | 0.86 | 0.90 | 0.86 | 0.95 |
| microglial cell | 11942 | 0.99 | 0.99 | 0.95 | 0.99 | 0.00 | 0.97 | 0.99 | 0.99 | 0.99 |
| T cell | 11498 | 0.77 | 0.79 | 0.77 | 0.84 | 0.00 | 0.89 | 0.68 | 0.75 | 0.88 |
| keratinocyte | 11126 | 0.86 | 0.87 | 0.91 | 0.93 | 0.00 | 0.88 | 0.89 | 0.86 | 0.92 |
| macrophage | 8645 | 0.45 | 0.63 | 0.83 | 0.77 | 0.00 | 0.74 | 0.56 | 0.60 | 0.82 |
| classical monocyte | 7327 | 0.83 | 0.54 | 0.78 | 0.90 | 0.00 | 0.89 | 0.82 | 0.84 | 0.93 |
| granulocytopoietic cell | 7276 | 0.65 | 0.79 | 0.85 | 0.86 | 0.00 | 0.76 | 0.70 | 0.81 | 0.88 |
| bladder urothelial cell | 5999 | 0.98 | 0.98 | 0.97 | 0.97 | 0.00 | 0.97 | 0.99 | 0.98 | 0.99 |
| mesenchymal stem cell of adipose tissue | 6012 | 0.81 | 0.81 | 0.84 | 0.76 | 0.00 | 0.94 | 0.90 | 0.81 | 0.93 |
| fibroblast of cardiac tissue | 5705 | 0.94 | 0.93 | 0.86 | 0.82 | 0.00 | 0.94 | 0.95 | 0.92 | 0.97 |
| endothelial cell of coronary artery | 5404 | 0.82 | 0.83 | 0.80 | 0.79 | 0.00 | 0.92 | 0.91 | 0.86 | 0.96 |
| skeletal muscle satellite cell | 4356 | 0.98 | 0.97 | 0.95 | 0.98 | 0.00 | 0.96 | 0.97 | 0.96 | 0.98 |
| proerythroblast | 4235 | 0.54 | 0.52 | 0.73 | 0.77 | 0.00 | 0.76 | 0.55 | 0.69 | 0.75 |
| kidney proximal convoluted tubule epithelial cell | 4024 | 0.84 | 0.81 | 0.89 | 0.89 | 0.00 | 0.87 | 0.90 | 0.89 | 0.92 |
| bronchial smooth muscle cell | 4024 | 0.94 | 0.96 | 0.82 | 0.90 | 0.00 | 0.93 | 0.96 | 0.95 | 0.97 |
| myeloid cell | 3977 | 0.51 | 0.56 | 0.73 | 0.70 | 0.00 | 0.85 | 0.72 | 0.72 | 0.86 |
| hepatocyte | 3690 | 0.99 | 0.98 | 0.98 | 0.98 | 0.00 | 0.97 | 0.99 | 0.99 | 0.99 |
| type B pancreatic cell | 3598 | 0.97 | 0.97 | 0.97 | 0.98 | 0.00 | 0.98 | 0.99 | 0.98 | 0.99 |
| bladder cell | 3627 | 0.97 | 0.95 | 0.98 | 0.81 | 0.00 | 0.96 | 0.99 | 0.94 | 0.99 |
| promonocyte | 3455 | 0.69 | 0.70 | 0.85 | 0.86 | 0.00 | 0.87 | 0.77 | 0.81 | 0.88 |
| DN4 thymocyte | 3418 | 0.35 | 0.46 | 0.60 | 0.68 | 0.00 | 0.88 | 0.63 | 0.69 | 0.78 |
| basal cell | 3366 | 0.98 | 0.97 | 0.98 | 0.97 | 0.00 | 0.97 | 0.99 | 0.97 | 0.99 |
| monocyte | 3281 | 0.66 | 0.53 | 0.77 | 0.81 | 0.00 | 0.86 | 0.80 | 0.81 | 0.90 |
| enterocyte of epithelium of large intestine | 3264 | 0.90 | 0.92 | 0.94 | 0.94 | 0.00 | 0.93 | 0.94 | 0.94 | 0.96 |
| thymocyte | 3145 | 0.74 | 0.75 | 0.86 | 0.93 | 0.00 | 0.91 | 0.91 | 0.92 | 0.96 |
| epithelial cell of proximal tubule | 3138 | 0.81 | 0.77 | 0.86 | 0.84 | 0.00 | 0.87 | 0.87 | 0.85 | 0.89 |
| natural killer cell | 3029 | 0.82 | 0.80 | 0.74 | 0.86 | 0.00 | 0.87 | 0.81 | 0.84 | 0.88 |
| naive B cell | 3015 | 0.44 | 0.20 | 0.89 | 0.66 | 0.00 | 0.76 | 0.52 | 0.56 | 0.83 |
| hematopoietic stem cell | 3000 | 0.92 | 0.93 | 0.94 | 0.94 | 0.00 | 0.92 | 0.95 | 0.94 | 0.96 |
| mature NK T cell | 2837 | 0.60 | 0.61 | 0.61 | 0.79 | 0.00 | 0.82 | 0.64 | 0.71 | 0.78 |
| fibroblast | 2836 | 0.46 | 0.26 | 0.69 | 0.66 | 0.00 | 0.70 | 0.67 | 0.65 | 0.79 |
| stromal cell | 2783 | 0.68 | 0.35 | 0.88 | 0.75 | 0.00 | 0.97 | 0.88 | 0.70 | 0.92 |
| keratinocyte stem cell | 2755 | 0.94 | 0.92 | 0.92 | 0.94 | 0.00 | 0.94 | 0.94 | 0.91 | 0.96 |
| erythroblast | 2652 | 0.65 | 0.69 | 0.83 | 0.84 | 0.00 | 0.83 | 0.72 | 0.77 | 0.85 |
| Kupffer cell | 2515 | 0.97 | 0.94 | 0.88 | 0.94 | 0.00 | 0.97 | 0.98 | 0.97 | 0.99 |
| megakaryocyte-erythroid progenitor cell | 2542 | 0.57 | 0.64 | 0.77 | 0.76 | 0.00 | 0.79 | 0.66 | 0.74 | 0.81 |
| pancreatic acinar cell | 2436 | 0.96 | 0.96 | 0.95 | 0.99 | 0.00 | 0.98 | 0.99 | 0.99 | 0.99 |
| luminal epithelial cell of mammary gland | 2410 | 0.92 | 0.91 | 0.98 | 0.93 | 0.00 | 0.97 | 0.97 | 0.94 | 0.98 |
| professional antigen presenting cell | 2381 | 0.06 | 0.01 | 0.30 | 0.53 | 0.00 | 0.92 | 0.39 | 0.42 | 0.56 |
| epidermal cell | 1978 | 0.84 | 0.86 | 0.89 | 0.89 | 0.00 | 0.82 | 0.88 | 0.85 | 0.91 |
| hematopoietic precursor cell | 1927 | 0.60 | 0.71 | 0.66 | 0.81 | 0.00 | 0.91 | 0.73 | 0.81 | 0.89 |
| oligodendrocyte | 1893 | 0.98 | 0.99 | 0.97 | 0.99 | 0.00 | 0.99 | 1.00 | 0.99 | 0.99 |
| fibroblast of lung | 1816 | 0.96 | 0.95 | 0.92 | 0.94 | 0.00 | 0.97 | 0.99 | 0.97 | 0.98 |
| CD8-positive, alpha-beta T cell | 1739 | 0.46 | 0.49 | 0.51 | 0.64 | 0.00 | 0.66 | 0.58 | 0.65 | 0.73 |
| epithelial cell of large intestine | 1719 | 0.78 | 0.78 | 0.85 | 0.83 | 0.00 | 0.84 | 0.88 | 0.87 | 0.89 |
| intestinal crypt stem cell | 1726 | 0.81 | 0.85 | 0.89 | 0.90 | 0.00 | 0.88 | 0.90 | 0.88 | 0.92 |
| chondrocyte | 1720 | 0.75 | 0.62 | 0.85 | 0.84 | 0.00 | 0.87 | 0.89 | 0.88 | 0.86 |
| immature T cell | 1597 | 0.71 | 0.00 | 0.83 | 0.94 | 0.00 | 0.93 | 0.87 | 0.90 | 0.96 |
| precursor B cell | 1601 | 0.71 | 0.86 | 0.93 | 0.89 | 0.00 | 0.89 | 0.84 | 0.89 | 0.93 |
| intermediate monocyte | 1568 | 0.19 | 0.04 | 0.48 | 0.67 | 0.00 | 0.68 | 0.58 | 0.60 | 0.75 |
| large intestine goblet cell | 1574 | 0.81 | 0.84 | 0.92 | 0.87 | 0.00 | 0.93 | 0.95 | 0.92 | 0.95 |
| CD4-positive, alpha-beta T cell | 1549 | 0.00 | 0.39 | 0.47 | 0.59 | 0.00 | 0.64 | 0.49 | 0.60 | 0.74 |
| smooth muscle cell | 1520 | 0.64 | 0.75 | 0.83 | 0.89 | 0.00 | 0.87 | 0.88 | 0.84 | 0.84 |
| leukocyte | 1491 | 0.48 | 0.49 | 0.70 | 0.66 | 0.00 | 0.79 | 0.61 | 0.70 | 0.91 |
| plasma cell | 1486 | 0.52 | 0.62 | 0.81 | 0.81 | 0.00 | 0.80 | 0.57 | 0.68 | 0.80 |
| lymphocyte | 1437 | 0.23 | 0.22 | 0.67 | 0.60 | 0.00 | 0.85 | 0.32 | 0.49 | 0.73 |
| naive T cell | 1408 | 0.79 | 0.86 | 0.93 | 0.92 | 0.00 | 0.81 | 0.90 | 0.88 | 0.90 |
| kidney loop of Henle thick ascending limb epithelial cell | 1392 | 0.90 | 0.91 | 0.93 | 0.85 | 0.00 | 0.92 | 0.96 | 0.96 | 0.96 |
| immature B cell | 1289 | 0.80 | 0.71 | 0.82 | 0.81 | 0.00 | 0.82 | 0.62 | 0.72 | 0.90 |
| alveolar macrophage | 1234 | 0.94 | 0.94 | 0.93 | 0.94 | 0.00 | 0.96 | 0.98 | 0.95 | 0.98 |
| endothelial cell of hepatic sinusoid | 1156 | 0.95 | 0.94 | 0.87 | 0.85 | 0.00 | 0.87 | 0.97 | 0.96 | 0.98 |
| lung macrophage | 1046 | 0.84 | 0.04 | 0.72 | 0.91 | 0.00 | 0.94 | 0.91 | 0.87 | 0.96 |
| non-classical monocyte | 1018 | 0.53 | 0.64 | 0.83 | 0.83 | 0.00 | 0.91 | 0.81 | 0.78 | 0.83 |
| endocardial cell | 953 | 0.92 | 0.92 | 0.94 | 0.87 | 0.00 | 0.92 | 0.92 | 0.85 | 0.96 |
| double negative thymocyte | 879 | 0.61 | 0.00 | 0.65 | 0.79 | 0.00 | 0.89 | 0.77 | 0.82 | 0.92 |
| late pro-B cell | 852 | 0.75 | 0.80 | 0.85 | 0.88 | 0.00 | 0.79 | 0.72 | 0.88 | 0.94 |
| kidney collecting duct principal cell | 826 | 0.73 | 0.89 | 0.91 | 0.88 | 0.00 | 0.89 | 0.97 | 0.96 | 0.97 |
| basal epithelial cell of tracheobronchial tree | 838 | 0.82 | 0.74 | 0.94 | 0.81 | 0.00 | 0.84 | 0.92 | 0.87 | 0.96 |
| mesenchymal cell | 781 | 0.23 | 0.00 | 0.41 | 0.30 | 0.00 | 0.44 | 0.56 | 0.56 | 0.55 |
| pancreatic A cell | 746 | 0.65 | 0.75 | 0.87 | 0.88 | 0.00 | 0.92 | 0.95 | 0.94 | 0.93 |
| adventitial cell | 725 | 0.66 | 0.59 | 0.86 | 0.54 | 0.00 | 0.70 | 0.84 | 0.65 | 0.92 |
| epithelial cell | 680 | 0.43 | 0.03 | 0.85 | 0.70 | 0.00 | 0.66 | 0.58 | 0.67 | 0.82 |
| kidney distal convoluted tubule epithelial cell | 682 | 0.82 | 0.88 | 0.88 | 0.74 | 0.00 | 0.95 | 0.97 | 0.96 | 0.96 |
| neutrophil | 626 | 0.51 | 0.50 | 0.76 | 0.83 | 0.00 | 0.76 | 0.73 | 0.67 | 0.88 |
| pancreatic ductal cell | 574 | 0.93 | 0.80 | 0.98 | 0.95 | 0.00 | 0.97 | 0.98 | 0.97 | 0.99 |
| myeloid dendritic cell | 570 | 0.47 | 0.53 | 0.87 | 0.65 | 0.00 | 0.86 | 0.75 | 0.62 | 0.80 |
| astrocyte | 531 | 0.91 | 0.93 | 0.97 | 0.95 | 0.00 | 0.97 | 1.00 | 0.99 | 0.99 |
| secretory cell | 507 | 0.26 | 0.35 | 0.82 | 0.69 | 0.00 | 0.90 | 0.93 | 0.88 | 0.93 |
| myeloid leukocyte | 458 | 0.57 | 0.33 | 0.86 | 0.55 | 0.00 | 0.69 | 0.63 | 0.71 | 0.94 |
| plasmatocyte | 454 | 0.81 | 0.78 | 0.91 | 0.82 | 0.00 | 0.82 | 0.89 | 0.88 | 0.95 |
| neuron | 437 | 0.61 | 0.57 | 0.86 | 0.81 | 0.00 | 0.78 | 0.95 | 0.91 | 0.93 |
| brain pericyte | 443 | 0.53 | 0.73 | 0.68 | 0.87 | 0.00 | 0.86 | 0.97 | 0.93 | 0.92 |
| vein endothelial cell | 414 | 0.48 | 0.77 | 0.80 | 0.70 | 0.00 | 0.78 | 0.86 | 0.80 | 0.93 |
| pancreatic D cell | 424 | 0.00 | 0.69 | 0.90 | 0.91 | 0.00 | 0.93 | 0.98 | 0.97 | 0.98 |
| kidney collecting duct epithelial cell | 425 | 0.39 | 0.51 | 0.84 | 0.86 | 0.00 | 0.95 | 0.91 | 0.87 | 0.94 |
| aortic endothelial cell | 421 | 0.16 | 0.00 | 0.27 | 0.43 | 0.00 | 0.70 | 0.38 | 0.32 | 0.74 |
| brush cell | 371 | 0.80 | 0.53 | 0.93 | 0.93 | 0.00 | 0.73 | 0.88 | 0.85 | 0.91 |
| erythroid progenitor cell, mammalian | 371 | 0.60 | 0.00 | 0.89 | 0.83 | 0.00 | 0.35 | 0.76 | 0.64 | 0.93 |
| regular atrial cardiac myocyte | 364 | 0.40 | 0.42 | 0.77 | 0.71 | 0.00 | 0.71 | 0.77 | 0.73 | 0.88 |
| kidney cortex artery cell | 339 | 0.78 | 0.83 | 0.75 | 0.50 | 0.00 | 0.40 | 0.75 | 0.71 | 0.79 |
| erythrocyte | 312 | 0.69 | 0.50 | 0.84 | 0.90 | 0.00 | 0.81 | 0.81 | 0.84 | 0.92 |
| mesangial cell | 316 | 0.00 | 0.64 | 0.67 | 0.74 | 0.00 | 0.69 | 0.84 | 0.77 | 0.94 |
| kidney loop of Henle ascending limb epithelial cell | 321 | 0.41 | 0.60 | 0.66 | 0.48 | 0.00 | 0.70 | 0.86 | 0.86 | 0.77 |
| cardiac muscle cell | 292 | 0.69 | 0.63 | 0.83 | 0.96 | 0.00 | 0.97 | 0.99 | 0.96 | 0.99 |
| mature alpha-beta T cell | 293 | 0.00 | 0.12 | 0.40 | 0.42 | 0.00 | 0.70 | 0.59 | 0.63 | 0.79 |
| basophil | 294 | 0.45 | 0.67 | 0.85 | 0.81 | 0.00 | 0.61 | 0.74 | 0.75 | 0.85 |
| cardiac valve cell | 291 | 0.73 | 0.82 | 0.75 | 0.87 | 0.00 | 0.85 | 0.93 | 0.89 | 0.91 |
| oligodendrocyte precursor cell | 274 | 0.95 | 0.97 | 0.97 | 0.98 | 0.00 | 0.98 | 0.99 | 1.00 | 1.00 |
| Schwann cell | 248 | 0.71 | 0.71 | 0.86 | 0.84 | 0.00 | 0.82 | 0.86 | 0.84 | 0.82 |
| pulmonary interstitial fibroblast | 248 | 0.94 | 0.85 | 0.91 | 0.89 | 0.00 | 0.94 | 0.91 | 0.96 | 0.96 |
| smooth muscle cell of trachea | 229 | 0.00 | 0.02 | 0.53 | 0.46 | 0.00 | 0.81 | 0.71 | 0.72 | 0.84 |
| granulocyte monocyte progenitor cell | 219 | 0.00 | 0.57 | 0.86 | 0.82 | 0.00 | 0.59 | 0.81 | 0.77 | 0.87 |
| interneuron | 218 | 0.52 | 0.56 | 0.81 | 0.74 | 0.00 | 0.78 | 0.97 | 0.91 | 0.91 |
| pancreatic PP cell | 201 | 0.00 | 0.05 | 0.72 | 0.78 | 0.00 | 0.85 | 0.92 | 0.93 | 0.93 |
| smooth muscle cell of the pulmonary artery | 189 | 0.00 | 0.70 | 0.79 | 0.42 | 0.00 | 0.48 | 0.87 | 0.78 | 0.88 |
| cell of skeletal muscle | 170 | 0.95 | 0.90 | 0.76 | 0.94 | 0.00 | 0.94 | 0.96 | 0.96 | 0.97 |
| brush cell of epithelium proper of large intestine | 160 | 0.66 | 0.70 | 0.85 | 0.87 | 0.00 | 0.83 | 0.97 | 0.94 | 0.92 |
| Langerhans cell | 153 | 0.91 | 0.78 | 0.91 | 0.77 | 0.00 | 0.68 | 0.90 | 0.78 | 0.96 |
| stem cell of epidermis | 158 | 0.00 | 0.00 | 0.74 | 0.79 | 0.00 | 0.37 | 0.60 | 0.61 | 0.89 |
| regulatory T cell | 155 | 0.00 | 0.06 | 0.20 | 0.22 | 0.00 | 0.44 | 0.52 | 0.35 | 0.77 |
| epithelial cell of thymus | 146 | 0.23 | 0.03 | 0.72 | 0.54 | 0.00 | 0.56 | 0.86 | 0.58 | 0.93 |
| enteroendocrine cell | 148 | 0.86 | 0.76 | 0.94 | 0.84 | 0.00 | 0.89 | 0.98 | 0.95 | 0.95 |
| kidney capillary endothelial cell | 145 | 0.24 | 0.50 | 0.38 | 0.32 | 0.00 | 0.31 | 0.31 | 0.32 | 0.30 |
| neuroepithelial stem cell | 130 | 0.17 | 0.08 | 0.87 | 0.69 | 0.00 | 0.54 | 0.93 | 0.69 | 0.82 |
| macrophage dendritic cell progenitor | 134 | 0.00 | 0.28 | 0.80 | 0.84 | 0.00 | 0.66 | 0.79 | 0.70 | 0.89 |
| DN3 thymocyte | 128 | 0.00 | 0.01 | 0.42 | 0.81 | 0.00 | 0.67 | 0.80 | 0.75 | 0.87 |
| regular ventricular cardiac myocyte | 135 | 0.46 | 0.04 | 0.89 | 0.79 | 0.00 | 0.91 | 0.95 | 0.99 | 0.97 |
| endothelial cell of lymphatic vessel | 133 | 0.00 | 0.43 | 0.94 | 0.66 | 0.00 | 0.31 | 0.64 | 0.48 | 0.89 |
| ciliated columnar cell of tracheobronchial tree | 119 | 0.00 | 0.82 | 0.76 | 0.93 | 0.00 | 0.67 | 0.96 | 0.94 | 0.97 |
| plasmacytoid dendritic cell | 112 | 0.00 | 0.23 | 0.87 | 0.67 | 0.00 | 0.44 | 0.72 | 0.70 | 0.90 |
| dendritic cell | 97 | 0.00 | 0.36 | 0.76 | 0.60 | 0.00 | 0.65 | 0.69 | 0.55 | 0.81 |
| medium spiny neuron | 91 | 0.00 | 0.12 | 0.93 | 0.87 | 0.00 | 0.94 | 1.00 | 0.99 | 0.99 |
| pericyte | 88 | 0.80 | 0.86 | 0.81 | 0.86 | 0.00 | 0.83 | 0.91 | 0.91 | 0.94 |
| neural stem cell | 85 | 0.46 | 0.53 | 0.88 | 0.92 | 0.00 | 0.79 | 0.96 | 0.94 | 0.96 |
| kidney proximal straight tubule epithelial cell | 86 | 0.00 | 0.00 | 0.09 | 0.00 | 0.00 | 0.25 | 0.60 | 0.45 | 0.41 |
| blood cell | 76 | 0.22 | 0.00 | 0.32 | 0.13 | 0.00 | 0.24 | 0.40 | 0.29 | 0.39 |
| immature NK T cell | 73 | 0.00 | 0.02 | 0.35 | 0.47 | 0.00 | 0.44 | 0.63 | 0.52 | 0.74 |
| cardiac neuron | 73 | 0.00 | 0.14 | 0.80 | 0.70 | 0.00 | 0.79 | 0.84 | 0.74 | 0.92 |
| mast cell | 66 | 0.00 | 0.00 | 0.62 | 0.87 | 0.00 | 0.73 | 0.63 | 0.67 | 0.85 |
| mucus secreting cell | 64 | 0.00 | 0.36 | 0.89 | 0.83 | 0.00 | 0.88 | 0.98 | 0.95 | 0.99 |
| early pro-B cell | 63 | 0.00 | 0.54 | 0.76 | 0.77 | 0.00 | 0.81 | 0.79 | 0.77 | 0.93 |
| pancreatic stellate cell | 57 | 0.81 | 0.69 | 0.90 | 0.57 | 0.00 | 0.22 | 0.54 | 0.85 | 0.94 |
| ependymal cell | 47 | 0.88 | 0.49 | 0.95 | 0.92 | 0.00 | 0.67 | 1.00 | 0.96 | 1.00 |
| Bergmann glial cell | 48 | 0.00 | 0.54 | 0.79 | 0.79 | 0.00 | 0.84 | 1.00 | 1.00 | 0.96 |
| neuroendocrine cell | 44 | 0.00 | 0.00 | 0.15 | 0.43 | 0.00 | 0.76 | 0.96 | 0.81 | 0.51 |
| fibrocyte | 39 | 0.00 | 0.00 | 0.43 | 0.36 | 0.00 | 0.22 | 0.73 | 0.57 | 0.77 |
| hepatic stellate cell | 37 | 0.00 | 0.10 | 0.82 | 0.85 | 0.00 | 0.36 | 0.96 | 0.86 | 0.99 |
| club cell | 35 | 0.13 | 0.41 | 0.27 | 0.16 | 0.00 | 0.19 | 0.23 | 0.22 | 0.17 |
| respiratory basal cell | 33 | 0.00 | 0.00 | 0.95 | 0.69 | 0.00 | 0.39 | 0.99 | 0.86 | 0.91 |
| kidney interstitial fibroblast | 14 | 0.00 | 0.00 | 0.78 | 0.90 | 0.00 | 0.36 | 0.38 | 0.78 | 0.93 |
| lymphoid lineage restricted progenitor cell | 13 | 0.96 | 0.00 | 0.87 | 0.78 | 0.00 | 0.25 | 0.09 | 0.96 | 0.96 |
| lung neuroendocrine cell | 8 | 0.00 | 0.00 | 1.00 | 0.67 | 0.00 | 0.59 | 0.62 | 1.00 | 1.00 |
| kidney cell | 3 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.32 | 0.11 | 0.75 | 0.50 |
| duct epithelial cell | 1 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.07 | 0.25 | 0.67 | 0.00 |
</details>
# References
A single-cell transcriptomic atlas characterizes ageing tissues in the mouse, The Tabula Muris Consortium, Nicole Almanzar, Jane Antony, Ankit S. Baghel, Isaac Bakerman, Ishita Bansal, Ben A. Barres, Philip A. Beachy, Daniela Berdnik, Biter Bilen, Douglas Brownfield, Corey Cain, Charles K. F. Chan, Michelle B. Chen, Michael F. Clarke, Stephanie D. Conley, Spyros Darmanis, Aaron Demers, Kubilay Demir, Antoine de Morree, Tessa Divita, Haley du Bois, Hamid Ebadi, F. Hernán Espinoza, Matt Fish, Qiang Gan, Benson M. George, Astrid Gillich, Rafael Gòmez-Sjöberg, Foad Green, Geraldine Genetiano, Xueying Gu, Gunsagar S. Gulati, Oliver Hahn, Michael Seamus Haney, Yan Hang, Lincoln Harris, Mu He, Shayan Hosseinzadeh, Albin Huang, Kerwyn Casey Huang, Tal Iram, Taichi Isobe, Feather Ives, Robert C. Jones, Kevin S. Kao, Jim Karkanias, Guruswamy Karnam, Andreas Keller, Aaron M. Kershner, Nathalie Khoury, Seung K. Kim, Bernhard M. Kiss, William Kong, Mark A. Krasnow, Maya E. Kumar, Christin S. Kuo, Jonathan Lam, Davis P. Lee, Song E. Lee, Benoit Lehallier, Olivia Leventhal, Guang Li, Qingyun Li, Ling Liu, Annie Lo, Wan-Jin Lu, Maria F. Lugo-Fagundo, Anoop Manjunath, Andrew P. May, Ashley Maynard, Aaron McGeever, Marina McKay, M. Windy McNerney, Bryan Merrill, Ross J. Metzger, Marco Mignardi, Dullei Min, Ahmad N. Nabhan, Norma F. Neff, Katharine M. Ng, Patricia K. Nguyen, Joseph Noh, Roel Nusse, Róbert Pálovics, Rasika Patkar, Weng Chuan Peng, Lolita Penland, Angela Oliveira Pisco, Katherine Pollard, Robert Puccinelli, Zhen Qi, Stephen R. Quake, Thomas A. Rando, Eric J. Rulifson, Nicholas Schaum, Joe M. Segal, Shaheen S. Sikandar, Rahul Sinha, Rene V. Sit, Justin Sonnenburg, Daniel Staehli, Krzysztof Szade, Michelle Tan, Weilun Tan, Cristina Tato, Krissie Tellez, Laughing Bear Torrez Dulgeroff, Kyle J. Travaglini, Carolina Tropini, Margaret Tsui, Lucas Waldburger, Bruce M. Wang, Linda J. van Weele, Kenneth Weinberg, Irving L. Weissman, Michael N. Wosczyna, Sean M. Wu, Tony Wyss-Coray, Jinyi Xiang, Soso Xue, Kevin A. Yamauchi, Andrew C. Yang, Lakshmi P. Yerra, Justin Youngyunpipatkul, Brian Yu, Fabio Zanini, Macy E. Zardeneta, Alexander Zee, Chunyu Zhao, Fan Zhang, Hui Zhang, Martin Jinye Zhang, Lu Zhou, James Zou; Nature, doi: https://doi.org/10.1038/s41586-020-2496-1
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