Yuning You
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README.md
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# CIFM: Cellular Interaction Foundation Model
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## Overview
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This is the PyTorch implementation of the CIFM model -- an AI model that can simulate the activities within living tissues (AI virtual tissue).
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The current version of CIFM has 100M parameters and is trained on around 23M cells of spatial genomics. The signature functions of CIFM are:
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- **Embedding** of celllular microenvironments via ```embeddings = model.embed(adata)``` (the 1st Figure below panel D top);
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- **Inference/simulation** of cellular gene expressions within a certain microenvironment via ```expressions = model.predict_cells_at_locations(adata, target_locs)``` (the 1st Figure below panel D bottom, and the 2nd Figure below).
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# CIFM: Cellular Interaction Foundation Model
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## Overview
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This is the PyTorch implementation of the CIFM model -- an AI foundation model that can simulate the activities within living tissues (AI virtual tissue).
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The current version of CIFM has 100M parameters and is trained on around 23M cells of spatial genomics. The signature functions of CIFM are:
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- **Embedding** of celllular microenvironments via ```embeddings = model.embed(adata)``` (the 1st Figure below panel D top);
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- **Inference/simulation** of cellular gene expressions within a certain microenvironment via ```expressions = model.predict_cells_at_locations(adata, target_locs)``` (the 1st Figure below panel D bottom, and the 2nd Figure below).
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