Datasets:

BrentLab
/

yeast_genome_resources

start float64 53 1.53M	end float64 535 1.53M	strand stringclasses 2 values	type stringclasses 10 values	locus_tag stringlengths 5 9	symbol stringlengths 2 10	alias stringlengths 2 135	source stringclasses 1 value	note stringlengths 15 511
335	649	+	gene	YAL069W	YAL069W	unknown_1	sgd/S288C_reference_genome_R64-3-1_20210421	Dubious open reading frame B unlikely to encode a functional protein C based on available experimental and comparative sequence data
538	792	+	gene	YAL068W-A	YAL068W-A	unknown_2	sgd/S288C_reference_genome_R64-3-1_20210421	Dubious open reading frame B unlikely to encode a functional protein C based on available experimental and comparative sequence data B identified by gene-trapping C microarray-based expression analysis C and genome-wide homology searching
1,807	2,169	-	gene	YAL068C	PAU8	PAU8,seripauperin_PAU8	sgd/S288C_reference_genome_R64-3-1_20210421	Protein of unknown function B member of the seripauperin multigene family encoded mainly in subtelomeric regions
2,480	2,707	+	gene	YAL067W-A	YAL067W-A	unknown_4	sgd/S288C_reference_genome_R64-3-1_20210421	Putative protein of unknown function B identified by gene-trapping C microarray-based expression analysis C and genome-wide homology searching
7,235	9,016	-	gene	YAL067C	SEO1	SEO1,putative_permease_SEO1	sgd/S288C_reference_genome_R64-3-1_20210421	Putative permease B member of the allantoate transporter subfamily of the major facilitator superfamily B mutation confers resistance to ethionine sulfoxide
10,091	10,399	+	gene	YAL066W	YAL066W	unknown_6	sgd/S288C_reference_genome_R64-3-1_20210421	Dubious open reading frame B unlikely to encode a functional protein C based on available experimental and comparative sequence data
11,565	11,951	-	gene	YAL065C	YAL065C	unknown_7	sgd/S288C_reference_genome_R64-3-1_20210421	Putative protein of unknown function B shows sequence similarity to FLO1 and other flocculins
12,046	12,426	+	gene	YAL064W-B	YAL064W-B	unknown_8	sgd/S288C_reference_genome_R64-3-1_20210421	Fungal-specific protein of unknown function
13,363	13,743	-	gene	YAL064C-A	TDA8	TDA8,YAL065C-A	sgd/S288C_reference_genome_R64-3-1_20210421	Putative protein of unknown function B null mutant is sensitive to expression of the top1-T722A allele B not an essential gene
21,566	21,850	+	gene	YAL064W	YAL064W	unknown_10	sgd/S288C_reference_genome_R64-3-1_20210421	Protein of unknown function B may interact with ribosomes C based on co-purification experiments
22,395	22,685	-	gene	YAL063C-A	YAL063C-A	unknown_11	sgd/S288C_reference_genome_R64-3-1_20210421	Putative protein of unknown function B identified by expression profiling and mass spectrometry
24,000	27,968	-	gene	YAL063C	FLO9	FLO9,flocculin_FLO9	sgd/S288C_reference_genome_R64-3-1_20210421	Lectin-like protein with similarity to Flo1p B thought to be expressed and involved in flocculation
31,567	32,940	+	gene	YAL062W	GDH3	GDH3,FUN51,glutamate_dehydrogenase__NADP_+___GDH3	sgd/S288C_reference_genome_R64-3-1_20210421	NADP + -dependent glutamate dehydrogenase B synthesizes glutamate from ammonia and alpha-ketoglutarate B rate of alpha-ketoglutarate utilization differs from Gdh1p B expression regulated by nitrogen and carbon sources B GDH3 has a paralog C GDH1 C that arose from the whole genome duplication
33,448	34,701	+	gene	YAL061W	BDH2	BDH2,putative_dehydrogenase_BDH2	sgd/S288C_reference_genome_R64-3-1_20210421	Putative medium-chain alcohol dehydrogenase with similarity to BDH1 B transcription induced by constitutively active PDR1 and PDR3
35,155	36,303	+	gene	YAL060W	BDH1	BDH1,_R_CR_-butanediol_dehydrogenase,BDH	sgd/S288C_reference_genome_R64-3-1_20210421	NAD-dependent R CR -butanediol dehydrogenase B catalyzes oxidation of R CR -2 C3-butanediol to R -acetoin C oxidation of meso-butanediol to S -acetoin C and reduction of acetoin B enhances use of C3-butanediol as an aerobic carbon source
36,496	36,918	-	gene	YAL059C-A	YAL059C-A	unknown_16	sgd/S288C_reference_genome_R64-3-1_20210421	Dubious open reading frame B unlikely to encode a functional protein C based on available experimental and comparative sequence data B partially overlaps verified gene ECM1/YAL059W
36,509	37,147	+	gene	YAL059W	ECM1	ECM1	sgd/S288C_reference_genome_R64-3-1_20210421	Pre-ribosomal factor involved in S ribosomal protein subunit export B associates with the pre-60S particle B shuttles between the nucleus and cytoplasm
37,464	38,972	+	gene	YAL058W	CNE1	CNE1,FUN48,calnexin	sgd/S288C_reference_genome_R64-3-1_20210421	Calnexin B integral membrane ER chaperone involved in folding and quality control of glycoproteins B chaperone activity is inhibited by Mpd1p C with which Cne1p interacts B % identical to mammalian calnexin B Ca+ binding not yet shown in yeast
38,696	39,046	-	gene	YAL056C-A	YAL056C-A	YAL058C-A	sgd/S288C_reference_genome_R64-3-1_20210421	Dubious open reading frame B unlikely to encode a functional protein C based on available experimental and comparative sequence data
39,259	41,901	+	gene	YAL056W	GPB2	GPB2,KRH1	sgd/S288C_reference_genome_R64-3-1_20210421	Multistep regulator of cAMP-PKA signaling B inhibits PKA downstream of Gpa2p and Cyr1p C thereby increasing cAMP dependency B inhibits Ras activity through direct interactions with Ira1p/2p B regulated by G-alpha protein Gpa2p B GPB2 has a paralog C GPB1 C that arose from the whole genome duplication
42,177	42,719	+	gene	YAL055W	PEX22	PEX22,YAF5,ubiquitin-protein_transferase_activating_protein_PEX22	sgd/S288C_reference_genome_R64-3-1_20210421	Putative peroxisomal membrane protein B required for import of peroxisomal proteins B functionally complements a Pichia pastoris pex22 mutation
42,881	45,022	-	gene	YAL054C	ACS1	ACS1,FUN44,acetate--CoA_ligase_	sgd/S288C_reference_genome_R64-3-1_20210421	Acetyl-coA synthetase isoform B along with Acs2p C acetyl-coA synthetase isoform is the nuclear source of acetyl-coA for histone acetylation B expressed during growth on nonfermentable carbon sources and under aerobic conditions
45,899	48,250	+	gene	YAL053W	FLC2	FLC2,flavin_adenine_dinucleotide_transporter_FLC2	sgd/S288C_reference_genome_R64-3-1_20210421	Putative calcium channel involved in calcium release under hypotonic stress B required for uptake of FAD into endoplasmic reticulum B involved in cell wall maintenance B FLC2 has a paralog C YOR365C C that arose from the whole genome duplication
48,564	51,707	+	gene	YAL051W	OAF1	OAF1,YAF1,oleate-activated_transcription_factor_OAF1	sgd/S288C_reference_genome_R64-3-1_20210421	Oleate-activated transcription factor B subunit of a heterodimeric complex with Pip2p C which binds to oleate-response elements ORE in the promoter of genes involved in beta-oxidation of fatty acids C peroxisome organization and biogenesis C activating transcription in the presence of oleate B regulates chromatin silencing at telomeres B involved in diauxic shift B OAF1 has a paralog C PIP2 C that arose from the whole genome duplication
51,855	52,595	-	gene	YAL049C	AIM2	AIM2,protein_AIM2	sgd/S288C_reference_genome_R64-3-1_20210421	Cytoplasmic protein involved in mitochondrial function or organization B null mutant displays reduced frequency of mitochondrial genome loss B potential Hsp82p interactor
52,801	54,789	-	gene	YAL048C	GEM1	GEM1,ERMES_complex_Ca_+_-binding_regulatory_GTPase_GEM1,GON1	sgd/S288C_reference_genome_R64-3-1_20210421	Outer mitochondrial membrane GTPase C subunit of the ERMES complex B potential regulatory subunit of the ERMES complex that links the ER to mitochondria and may promote inter-organellar calcium and phospholipid exchange as well as coordinating mitochondrial DNA replication and growth B cells lacking Gem1p contain collapsed C globular C or grape-like mitochondria B ortholog of metazoan Miro GTPases
54,584	54,913	+	gene	YAL047W-A	YAL047W-A	unknown_27	sgd/S288C_reference_genome_R64-3-1_20210421	Dubious open reading frame B unlikely to encode a functional protein C based on available experimental and comparative sequence data B partially overlaps ORF GEM1/YAL048C
54,989	56,857	-	gene	YAL047C	SPC72	SPC72,LDB4,gamma-tubulin_complex_subunit_SPC72	sgd/S288C_reference_genome_R64-3-1_20210421	Gamma-tubulin small complex gamma-TuSC receptor B recruits the gamma-TuSC complex to the cytoplasmic side of the SPB C connecting nuclear microtubules to the SPB B involved in astral microtubule formation C stabilization C and with Stu2p C anchoring astral MTs at the cytoplasmic face of the SPB C and regulating plus-end MT dynamics B regulated by Cdc5 kinase
57,029	57,385	-	gene	YAL046C	BOL3	BOL3,AIM1	sgd/S288C_reference_genome_R64-3-1_20210421	Protein involved in Fe-S cluster transfer to mitochondrial clients B protects [4Fe-4S] clusters from damage due to oxidative stress by acting along with Nfu1p at a late step in the transfer of [4Fe-4S] clusters from the ISA complex to mitochondrial client proteins like lipoate synthase and succinate dehydrogenase B sequence similarity to human BOLA family member C BOLA3 C mutations of which are associated with Multiple Mitochondria Dysfunctions Syndrome MMDS2
57,488	57,796	-	gene	YAL045C	YAL045C	unknown_30	sgd/S288C_reference_genome_R64-3-1_20210421	Dubious open reading frame B unlikely to encode a functional protein C based on available experimental and comparative sequence data B almost completely overlaps YAL044W-A
57,518	57,850	+	gene	YAL044W-A	BOL1	BOL1	sgd/S288C_reference_genome_R64-3-1_20210421	Mitochondrial matrix protein involved in Fe-S cluster biogenesis B facilitates [4Fe-2S] cluster inception into mitochondrial proteins such as lipoate synthase and succinate dehydrogenase B interacts and may function with Grx5p at an early step in Fe-S cluster biosynthesis B forms dimeric complexes with Grx5p and Nfu1p that alter the stability of shared Fe/S clusters B sequence similarity to human BOLA family member C BOLA1 and S. pombe uvi31 C a putative DNA repair protein
57,950	58,462	-	gene	YAL044C	GCV3	GCV3,glycine_decarboxylase_subunit_H	sgd/S288C_reference_genome_R64-3-1_20210421	H subunit of the mitochondrial glycine decarboxylase complex B glycine decarboxylase is required for the catabolism of glycine to C10-methylene-THF B also required for all protein lipoylation B expression is regulated by levels of C10-methylene-THF
58,695	61,052	-	gene	YAL043C	PTA1	PTA1,FUN39,RNA-processing_protein_PTA1	sgd/S288C_reference_genome_R64-3-1_20210421	Subunit of holo-CPF B holo-CPF is a multiprotein complex and functional homolog of mammalian CPSF C required for the cleavage and polyadenylation of mRNA and snoRNA ' ends B involved in pre-tRNA processing B binds to the phosphorylated CTD of RNAPII
61,231	61,608	-	gene	YAL042C-A	YAL042C-A	YAL043C-A	sgd/S288C_reference_genome_R64-3-1_20210421	Dubious open reading frame B unlikely to encode a functional protein C based on available experimental and comparative sequence data B partially overlaps verified ORF ERV46/YAL042W B YAL042C-A is a non-essential gene
61,316	62,563	+	gene	YAL042W	ERV46	ERV46,FUN9	sgd/S288C_reference_genome_R64-3-1_20210421	Protein localized to COPII-coated vesicles B forms a complex with Erv41p B involved in the membrane fusion stage of transport
62,840	65,404	+	gene	YAL041W	CDC24	CDC24,CLS4,Rho_family_guanine_nucleotide_exchange_factor_CDC24	sgd/S288C_reference_genome_R64-3-1_20210421	Guanine nucleotide exchange factor GEF for Cdc42p B required for polarity establishment and maintenance C and mutants have morphological defects in bud formation and shmooing B relocalizes from nucleus to cytoplasm upon DNA replication stress B thermosensitivity of the cdc24-4 mutant in the presence of sorbitol is functionally complemented by human CDC42
65,778	67,520	-	gene	YAL040C	CLN3	CLN3,DAF1,FUN10,WHI1,cyclin_CLN3	sgd/S288C_reference_genome_R64-3-1_20210421	G1 cyclin involved in cell cycle progression B activates Cdc28p kinase to promote G1 to S phase transition B plays a role in regulating transcription of other G1 cyclins C CLN1 and CLN2 B regulated by phosphorylation and proteolysis B acetyl-CoA induces CLN3 transcription in response to nutrient repletion to promote cell-cycle entry B cell cycle arrest phenotype of the cln1 cln2 cln3 triple null mutant is complemented by any of human cyclins CCNA2 C CCNB1 C CCNC C CCND1 C or CCNE1
68,716	69,525	-	gene	YAL039C	CYC3	CYC3,CCHL,holocytochrome_c_synthase_CYC3	sgd/S288C_reference_genome_R64-3-1_20210421	Cytochrome c heme lyase holocytochrome c synthase B attaches heme to apo-cytochrome c Cyc1p or Cyc7p in mitochondrial intermembrane space B human homolog HCCS implicated in microphthalmia with linear skin defects MLS C and can complement yeast null mutant
71,786	73,288	+	gene	YAL038W	CDC19	CDC19,PYK1,pyruvate_kinase_CDC19	sgd/S288C_reference_genome_R64-3-1_20210421	Pyruvate kinase B functions as a homotetramer in glycolysis to convert phosphoenolpyruvate to pyruvate C the input for aerobic TCA cycle or anaerobic glucose fermentation respiration B regulated via allosteric activation by fructose bisphosphate B CDC19 has a paralog C PYK2 C that arose from the whole genome duplication
72,326	73,300	-	gene	YAL037C-B	YAL037C-B	unknown_40	sgd/S288C_reference_genome_R64-3-1_20210421	Dubious open reading frame B unlikely to encode a functional protein C based on available experimental and comparative sequence data B identified by gene-trapping C microarray-based expression analysis C and genome-wide homology searching
73,426	73,518	-	gene	YAL037C-A	YAL037C-A	unknown_41	sgd/S288C_reference_genome_R64-3-1_20210421	Putative protein of unknown function
74,020	74,823	+	gene	YAL037W	YAL037W	unknown_42	sgd/S288C_reference_genome_R64-3-1_20210421	Putative protein of unknown function B YAL037W has a paralog C YOR342C C that arose from the whole genome duplication
75,043	76,152	-	gene	YAL036C	RBG1	RBG1,FUN11,GTP-binding_protein_RBG1	sgd/S288C_reference_genome_R64-3-1_20210421	Member of the DRG family of GTP-binding proteins B associates with translating ribosomes B interacts with Tma46p C Ygr250cp C Gir2p and Yap1p via two-hybrid
76,427	79,435	+	gene	YAL035W	FUN12	FUN12,eIF5B,translation_initiation_factor_eIF5B,yIF2	sgd/S288C_reference_genome_R64-3-1_20210421	Translation initiation factor eIF5B B GTPase that promotes Met-tRNAiMet binding to ribosomes and ribosomal subunit joining B promotes GTP-dependent maturation of S rRNA by Nob1p B protein abundance increases in response to DNA replication stress B homolog of bacterial IF2
79,489	79,842	-	gene	YAL034C-B	YAL034C-B	YAL035C-A	sgd/S288C_reference_genome_R64-3-1_20210421	Dubious open reading frame B unlikely to encode a functional protein C based on available experimental and comparative sequence data
79,718	80,587	+	gene	YAL034W-A	MTW1	MTW1,DSN3,MIND_complex_subunit_MTW1,NSL2	sgd/S288C_reference_genome_R64-3-1_20210421	Essential component of the MIND kinetochore complex B joins kinetochore subunits contacting DNA to those contacting microtubules B critical to kinetochore assembly B complex consists of Mtw1p Including Nnf1p-Nsl1p-Dsn1p MIND
80,710	81,951	-	gene	YAL034C	FUN19	FUN19	sgd/S288C_reference_genome_R64-3-1_20210421	Non-essential protein of unknown function B expression induced in response to heat stress B FUN19 has a paralog C YOR338W C that arose from the whole genome duplication
82,706	83,227	+	gene	YAL033W	POP5	POP5,FUN53,RNA-binding_protein_POP5	sgd/S288C_reference_genome_R64-3-1_20210421	Subunit of both RNase MRP and nuclear RNase P B RNase MRP cleaves pre-rRNA C while nuclear RNase P cleaves tRNA precursors to generate mature ' ends and facilitates turnover of nuclear RNAs
83,335	84,474	-	gene	YAL032C	PRP45	PRP45,FUN20,mRNA_splicing_protein_PRP45	sgd/S288C_reference_genome_R64-3-1_20210421	Protein required for pre-mRNA splicing B associates with the spliceosome and interacts with splicing factors Prp22p and Prp46p B orthologous to human transcriptional coactivator SKIP and can activate transcription of a reporter gene
84,669	84,977	+	gene	YAL031W-A	YAL031W-A	unknown_50	sgd/S288C_reference_genome_R64-3-1_20210421	Dubious open reading frame B unlikely to encode a functional protein C based on available experimental and comparative sequence data B partially overlaps ORF GIP4/YAL031C
84,749	87,031	-	gene	YAL031C	GIP4	GIP4,FUN21,protein_phosphatase_regulator_GIP4	sgd/S288C_reference_genome_R64-3-1_20210421	Cytoplasmic protein that regulates protein phosphatase Glc7p B protein overexpression relocalizes Glc7p from the nucleus and prevents chromosome segregation B potential Cdc28p substrate
87,286	87,752	+	gene	YAL030W	SNC1	SNC1,SNAP_receptor_SNC1	sgd/S288C_reference_genome_R64-3-1_20210421	Vesicle membrane receptor protein v-SNARE B involved in the fusion between Golgi-derived secretory vesicles with the plasma membrane B proposed to be involved in endocytosis B member of the synaptobrevin/VAMP family of R-type v-SNARE proteins B SNC1 has a paralog C SNC2 C that arose from the whole genome duplication
87,855	92,270	-	gene	YAL029C	MYO4	MYO4,FUN22,SHE1,myosin_	sgd/S288C_reference_genome_R64-3-1_20210421	Type V myosin motor involved in actin-based transport of cargos B required for mRNA transport C including ASH1 mRNA C and facilitating the growth and movement of ER tubules into the growing bud along with She3p B MYO4 has a paralog C MYO2 C that arose from the whole genome duplication
92,900	94,486	+	gene	YAL028W	FRT2	FRT2,HPH2	sgd/S288C_reference_genome_R64-3-1_20210421	Tail-anchored ER membrane protein of unknown function B interacts with homolog Frt1p B promotes growth in conditions of high Na+ C alkaline pH C or cell wall stress C possibly via a role in posttranslational translocation B potential Cdc28p substrate B FRT2 has a paralog C FRT1 C that arose from the whole genome duplication
94,687	95,472	+	gene	YAL027W	SAW1	SAW1,DNA-binding_protein_SAW1	sgd/S288C_reference_genome_R64-3-1_20210421	5'- and '-flap DNA binding protein B recruits Rad1p-Rad10p to single-strand annealing intermediates with ' non-homologous tails for removal during double-strand break repair B complexes with Rad1p-Rad10p and stimulates its endonuclease activity B green fluorescent protein GFP -fusion protein localizes to the nucleus
95,386	95,823	-	gene	YAL026C-A	YAL026C-A	unknown_56	sgd/S288C_reference_genome_R64-3-1_20210421	Dubious open reading frame B unlikely to encode a functional protein C based on available experimental and comparative sequence data B partially overlaps the uncharacterized ORF YAL027W and the verified gene DRS2
95,630	99,697	-	gene	YAL026C	DRS2	DRS2,FUN38,SWA3,aminophospholipid-translocating_P4-type_ATPase_DRS2	sgd/S288C_reference_genome_R64-3-1_20210421	Trans-golgi network aminophospholipid translocase flippase B maintains membrane lipid asymmetry in post-Golgi secretory vesicles B contributes to clathrin-coated vesicle formation C endocytosis C protein trafficking between the Golgi and endosomal system and the cellular response to mating pheromone B autoinhibited by its C-terminal tail B localizes to the trans-Golgi network B mutations in human homolog ATP8B1 result in liver disease
99,305	99,868	+	ncRNA_gene	YNCA0001W	HRA1	HRA1	sgd/S288C_reference_genome_R64-3-1_20210421	Non-protein-coding RNA B substrate of RNase P C possibly involved in rRNA processing C specifically maturation of S precursor into the mature S rRNA
100,225	101,145	-	gene	YAL025C	MAK16	MAK16,ribosome_biosynthesis_protein_MAK16	sgd/S288C_reference_genome_R64-3-1_20210421	Essential nuclear protein B constituent of S pre-ribosomal particles B required for maturation of S and .8S rRNAs B required for maintenance of M1 satellite double-stranded RNA of the L-A virus
101,565	105,872	-	gene	YAL024C	LTE1	LTE1,MSI2,mitotic_regulator_LTE1	sgd/S288C_reference_genome_R64-3-1_20210421	Protein similar to GDP/GTP exchange factors B without detectable GEF activity B required for asymmetric localization of Bfa1p at daughter-directed spindle pole bodies and for mitotic exit at low temperatures
106,272	108,551	-	gene	YAL023C	PMT2	PMT2,FUN25,dolichyl-phosphate-mannose-protein_mannosyltransferase_PMT2	sgd/S288C_reference_genome_R64-3-1_20210421	Protein O-mannosyltransferase of the ER membrane B transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues B involved in ER quality control B functions as a heterodimer with Pmt2p but can also pair with Pmt5p B antifungal drug target B PMT2 has a paralog C PMT3 C that arose from the whole genome duplication
108,877	110,430	-	gene	YAL022C	FUN26	FUN26,nucleoside_transmembrane_transporter_FUN26	sgd/S288C_reference_genome_R64-3-1_20210421	High affinity C broad selectivity C nucleoside/nucleobase transporter B vacuolar membrane localized transporter which may regulate the balance of nicotinamide riboside NmR levels between the cytosol and vacuole C contributing to salvage of NmR for use in cytosolic NAD+ synthesis B equilibrative nucleoside transporter ENT family member
110,846	113,359	-	gene	YAL021C	CCR4	CCR4,CCR4-NOT_core_exoribonuclease_subunit_CCR4,FUN27,NUT21	sgd/S288C_reference_genome_R64-3-1_20210421	Component of the CCR4-NOT transcriptional complex B CCR4-NOT is involved in regulation of gene expression B component of the major cytoplasmic deadenylase C which is involved in mRNA poly A tail shortening
113,614	114,615	-	gene	YAL020C	ATS1	ATS1,FUN28,KTI13	sgd/S288C_reference_genome_R64-3-1_20210421	Protein required for modification of wobble nucleosides in tRNA B acts with Elongator complex C Kti11p C and Kti12p B has a potential role in regulatory interactions between microtubules and the cell cycle B forms a stable heterodimer with Kti11p
114,250	114,819	+	gene	YAL019W-A	YAL019W-A	unknown_65	sgd/S288C_reference_genome_R64-3-1_20210421	Dubious open reading frame B unlikely to encode a functional protein C based on available experimental and comparative sequence data B partially overlaps ORF ATS1/YAL020C
114,919	118,314	+	gene	YAL019W	FUN30	FUN30,DNA-dependent_ATPase_FUN30	sgd/S288C_reference_genome_R64-3-1_20210421	Snf2p family member with ATP-dependent chromatin remodeling activity B has a role in silencing at the mating type locus C telomeres and centromeres B enriched at centromeres and is required for correct chromatin structure around centromeres C as well as at the boundary element of the silent HMR B recruited to DNA double-strand breaks DSBs where it promotes ' strand resection of DSBs B potential Cdc28p substrate
118,564	119,541	-	gene	YAL018C	LDS1	LDS1	sgd/S288C_reference_genome_R64-3-1_20210421	Protein Involved in spore wall assembly B localizes to lipid droplets found on or outside of the prospore membrane B shares similarity with Lds2p and Rrt8p C and a strain mutant for all genes exhibits reduced dityrosine fluorescence relative to the single mutants
120,225	124,295	+	gene	YAL017W	PSK1	PSK1,FUN31,serine/threonine_protein_kinase_PSK1	sgd/S288C_reference_genome_R64-3-1_20210421	PAS domain-containing serine/threonine protein kinase B coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status B PSK1 has a paralog C PSK2 C that arose from the whole genome duplication
124,307	124,492	-	gene	YAL016C-B	YAL016C-B	unknown_69	sgd/S288C_reference_genome_R64-3-1_20210421	Dubious open reading frame B unlikely to encode a functional protein C based on available experimental and comparative sequence data
124,755	125,069	-	gene	YAL016C-A	YAL016C-A	unknown_70	sgd/S288C_reference_genome_R64-3-1_20210421	Dubious open reading frame B unlikely to encode a functional protein C based on available experimental and comparative sequence data B partially overlaps ORF TPD3/YAL016W
124,879	126,786	+	gene	YAL016W	TPD3	TPD3,FUN32,protein_phosphatase_A_structural_subunit_TPD3	sgd/S288C_reference_genome_R64-3-1_20210421	Regulatory subunit A of the heterotrimeric PP2A complex B the heterotrimeric protein phosphatase A PP2A complex also contains regulatory subunit Cdc55p and either catalytic subunit Pph21p or Pph22p B required for cell morphogenesis and transcription by RNA polymerase III
126,903	128,102	-	gene	YAL015C	NTG1	NTG1,FUN33,SCR1,bifunctional_N-glycosylase/AP_lyase_NTG1,ogg2	sgd/S288C_reference_genome_R64-3-1_20210421	DNA N-glycosylase and apurinic/apyrimidinic AP lyase B involved in base excision repair B acts in both nucleus and mitochondrion B creates a double-strand break at mtDNA origins that stimulates replication in response to oxidative stress B required for maintaining mitochondrial genome integrity B NTG1 has a paralog C NTG2 C that arose from the whole genome duplication
128,252	129,019	-	gene	YAL014C	SYN8	SYN8,SLT2,UIP2,syntaxin	sgd/S288C_reference_genome_R64-3-1_20210421	Endosomal SNARE related to mammalian syntaxin
129,270	130,487	+	gene	YAL013W	DEP1	DEP1,FUN54,Rpd3L_histone_deacetylase_complex_subunit_DEP1	sgd/S288C_reference_genome_R64-3-1_20210421	Component of the Rpd3L histone deacetylase complex B required for diauxic shift-induced histone H2B deposition onto rDNA genes B transcriptional modulator involved in regulation of structural phospholipid biosynthesis genes and metabolically unrelated genes C as well as maintenance of telomeres C mating efficiency C and sporulation
130,799	131,983	+	gene	YAL012W	CYS3	CYS3,CYI1,FUN35,STR1,cystathionine_gamma-lyase_CYS3	sgd/S288C_reference_genome_R64-3-1_20210421	Cystathionine gamma-lyase B catalyzes one of the two reactions involved in the transsulfuration pathway that yields cysteine from homocysteine with the intermediary formation of cystathionine B protein abundance increases in response to DNA replication stress
132,199	134,076	+	gene	YAL011W	SWC3	SWC3,SWC1	sgd/S288C_reference_genome_R64-3-1_20210421	Protein of unknown function B component of the SWR1 complex C which exchanges histone variant H2AZ Htz1p for chromatin-bound histone H2A B required for formation of nuclear-associated array of smooth endoplasmic reticulum known as karmellae
192,337	192,417	-	gene	YAR035C-A	YAR035C-A	unknown_112	sgd/S288C_reference_genome_R64-3-1_20210421	Putative protein of unknown function B emerging ORF that arose de novo from non-genic locus B identified by gene-trapping C microarray-based expression analysis C and genome-wide homology searching B localizes to mitochondria
134,184	135,665	-	gene	YAL010C	MDM10	MDM10,FUN37	sgd/S288C_reference_genome_R64-3-1_20210421	Subunit of both the ERMES and the SAM complex B component of ERMES complex which acts as a molecular tether between the mitochondria and the ER C necessary for efficient phospholipid exchange between organelles and for mitophagy B SAM/TOB complex component that functions in the assembly of outer membrane beta-barrel proteins B involved in mitochondrial inheritance and morphology B ERMES complex is often co-localized with peroxisomes and concentrated areas of pyruvate dehydrogenase
135,854	136,633	+	gene	YAL009W	SPO7	SPO7,Nem1-Spo7_phosphatase_regulatory_subunit_SPO7	sgd/S288C_reference_genome_R64-3-1_20210421	Putative regulatory subunit of Nem1p-Spo7p phosphatase holoenzyme B regulates nuclear growth by controlling phospholipid biosynthesis C required for normal nuclear envelope morphology C premeiotic replication C and sporulation
136,914	137,510	+	gene	YAL008W	FUN14	FUN14,MCP3	sgd/S288C_reference_genome_R64-3-1_20210421	Integral mitochondrial outer membrane MOM protein B dosage suppressor of an MDM10 null that reduces ERMES-related phenotypes C such as alterations in mitochondrial morphology C protein complex assembly C and lipid profile B dosage suppressor of MDM12 C MDM34 C and MMM1 null mutant growth defects B novel mechanism of MOM import involving Tom70p C the TOM complex C and the TIM23 complex C requiring mitochondrial membrane potential and processing by the IMP complex for correct biogenesis
137,698	138,345	-	gene	YAL007C	ERP2	ERP2	sgd/S288C_reference_genome_R64-3-1_20210421	Member of the p24 family involved in ER to Golgi transport B similar to Emp24p and Erv25p B role in misfolded protein quality control B forms a heterotrimeric complex with Erp1p C Emp24p C and Erv25p B localized to COPII-coated vesicles B ERP2 has a paralog C ERP4 C that arose from the whole genome duplication
139,152	139,254	+	tRNA_gene	YNCA0002W	TRN1	TRN1,tP_UGG_A	sgd/S288C_reference_genome_R64-3-1_20210421	Proline tRNA tRNA-Pro C predicted by tRNAscan-SE analysis B target of K. lactis zymocin B can mutate to suppress +1 frameshift mutations in proline codons
139,503	141,431	-	gene	YAL005C	SSA1	SSA1,Hsp70_family_ATPase_SSA1,YG100	sgd/S288C_reference_genome_R64-3-1_20210421	ATPase involved in protein folding and NLS-directed nuclear transport B member of HSP70 family B required for ubiquitin-dependent degradation of short-lived proteins B forms chaperone complex with Ydj1p B localized to nucleus C cytoplasm C cell wall B % identical to paralog Ssa2p with different functional specificity in propagation of yeast [URE3] prions C vacuolar-mediated degradations of gluconeogenesis enzymes B general targeting factor of Hsp104p to prion fibrils
140,760	141,407	+	gene	YAL004W	YAL004W	unknown_83	sgd/S288C_reference_genome_R64-3-1_20210421	Dubious open reading frame B unlikely to encode a functional protein C based on available experimental and comparative sequence data B completely overlaps verified gene SSA1/YAL005C
142,174	143,160	+	gene	YAL003W	EFB1	EFB1,EF-1beta,TEF5,eEF1Balpha,translation_elongation_factor__subunit_beta	sgd/S288C_reference_genome_R64-3-1_20210421	Translation elongation factor beta B stimulates nucleotide exchange to regenerate EF-1 alpha-GTP for the next elongation cycle B part of the EF-1 complex C which facilitates binding of aminoacyl-tRNA to the ribosomal A site B human homolog EEF1B2 can complement yeast efb1 mutants
142,367	142,468	+	snoRNA_gene	YNCA0003W	SNR18	SNR18,snR18	sgd/S288C_reference_genome_R64-3-1_20210421	C/D box small nucleolar RNA snoRNA B commonly referred to as U18 B guides '-O-methylation of large subunit LSU rRNA at positions A649 and C650
143,707	147,531	+	gene	YAL002W	VPS8	VPS8,CORVET_complex_membrane-binding_subunit_VPS8,FUN15,VPL8,VPT8	sgd/S288C_reference_genome_R64-3-1_20210421	Membrane-binding component of the CORVET complex B involved in endosomal vesicle tethering and fusion in the endosome to vacuole protein targeting pathway B interacts with Vps21p B contains RING finger motif
147,594	151,166	-	gene	YAL001C	TFC3	TFC3,FUN24,TSV115,tau_,transcription_factor_TFIIIC_subunit_TFC3	sgd/S288C_reference_genome_R64-3-1_20210421	Subunit of RNA polymerase III transcription initiation factor complex B part of TauB domain of TFIIIC that binds DNA at BoxB promoter sites of tRNA and similar genes B cooperates with Tfc6p in DNA binding B largest of six subunits of RNA polymerase III transcription initiation factor complex TFIIIC B colocalizes with condensin at pol III genes and several ETC “extra TFIIIC ” sites B may have a role in recruiting or stabilizing Scc2/4 and condensin on chromosomes
152,257	153,876	+	gene	YAR002W	NUP60	NUP60,FG-nucleoporin_NUP60	sgd/S288C_reference_genome_R64-3-1_20210421	FG-nucleoporin component of central core of the nuclear pore complex B contributes directly to nucleocytoplasmic transport and maintenance of the nuclear pore complex NPC permeability barrier and is involved in gene tethering at the nuclear periphery B relocalizes to the cytosol in response to hypoxia B both NUP1 and NUP60 are homologous to human NUP153
154,065	154,724	-	gene	YAR002C-A	ERP1	ERP1	sgd/S288C_reference_genome_R64-3-1_20210421	Member of the p24 family involved in ER to Golgi transport B role in misfolded protein quality control B forms heterotrimeric complex with Erp2p C Emp24p C and Erv25p B localized to COPII-coated vesicles B ERP1 has a paralog C ERP6 C that arose from the whole genome duplication
155,005	156,285	+	gene	YAR003W	SWD1	SWD1,COMPASS_subunit_protein_SWD1,CPS50,FUN16,SAF49	sgd/S288C_reference_genome_R64-3-1_20210421	Subunit of the COMPASS Set1C complex B COMPASS methylates histone H3 on lysine and is required in transcriptional silencing near telomeres B WD40 beta propeller superfamily member with similarity to mammalian Rbbp7
156,754	158,619	-	gene	YAR007C	RFA1	RFA1,BUF2,FUN3,RPA1,RPA70,replication_factor_A_subunit_protein_RFA1	sgd/S288C_reference_genome_R64-3-1_20210421	Subunit of heterotrimeric Replication Protein A RPA B RPA is a highly conserved single-stranded DNA binding protein involved in DNA replication C repair C and recombination B RPA protects against inappropriate telomere recombination C and upon telomere uncapping C prevents cell proliferation by a checkpoint-independent pathway B role in DNA catenation/decatenation pathway of chromosome disentangling B relocalizes to the cytosol in response to hypoxia
192,619	196,185	+	gene	YAR042W	SWH1	SWH1,OSH1,YAR044W,oxysterol-binding_protein_related_protein_SWH1	sgd/S288C_reference_genome_R64-3-1_20210421	Protein similar to mammalian oxysterol-binding protein B contains ankyrin repeats and FFAT motif B interacts with ER anchor Scs2p at the nucleus-vacuole junction B regulated by sterol binding B SWH1 has a paralog C OSH2 C that arose from the whole genome duplication
158,966	159,793	+	gene	YAR008W	SEN34	SEN34,FUN4,tRNA_splicing_endonuclease_subunit_SEN34	sgd/S288C_reference_genome_R64-3-1_20210421	Subunit of the tRNA splicing endonuclease B tRNA splicing endonuclease Sen complex is composed of Sen2p C Sen15p C Sen34p C and Sen54p B Sen complex also cleaves the CBP1 mRNA at the mitochondrial surface B Sen34p contains the active site for tRNA ' splice site cleavage and has similarity to Sen2p and to Archaeal tRNA splicing endonuclease
160,597	164,187	-	transposable_element_gene	YAR009C	YAR009C	YARCTyB1-1,truncated_gag-pol_fusion_protein	sgd/S288C_reference_genome_R64-3-1_20210421	Retrotransposon TYA Gag and TYB Pol genes B Gag processing produces capsid proteins C Pol is cleaved to produce protease C reverse transcriptase and integrase activities B in YARCTy1-1 TYB is mutant and probably non-functional B protein product forms cytoplasmic foci upon DNA replication stress
164,544	165,866	-	transposable_element_gene	YAR010C	YAR010C	YARCTyA1-1,gag_protein	sgd/S288C_reference_genome_R64-3-1_20210421	Retrotransposon TYA Gag gene co-transcribed with TYB Pol B Gag processing produces capsid proteins B in YARCTy1-1 TYB is mutant and probably non-functional
166,267	166,339	+	tRNA_gene	YNCA0004W	TGA1	TGA1,tA_UGC_A	sgd/S288C_reference_genome_R64-3-1_20210421	Alanine tRNA tRNA-Ala C predicted by tRNAscan-SE analysis B one of nuclear tRNA genes containing the tDNA-anticodon TGC mature tRNA may be UGC or may contain modified bases C decodes GCA and probably GCG codons into alanine C one of nuclear tRNAs for alanine
166,742	168,871	-	gene	YAR014C	BUD14	BUD14,protein_phosphatase_regulator_BUD14	sgd/S288C_reference_genome_R64-3-1_20210421	Protein involved in bud-site selection B Bud14p-Glc7p complex is a cortical regulator of dynein B forms a complex with Kel1p and Kel2p that regulates Bnr1p formin to affect actin cable assembly C cytokinesis C and polarized growth B diploid mutants display a random budding pattern instead of the wild-type bipolar pattern B relative distribution to the nucleus increases upon DNA replication stress
169,375	170,295	+	gene	YAR015W	ADE1	ADE1,phosphoribosylaminoimidazolesuccinocarboxamide_synthase	sgd/S288C_reference_genome_R64-3-1_20210421	N-succinyl-5-aminoimidazole-4-carboxamide ribotide synthetase B required for 'de novo' purine nucleotide biosynthesis B red pigment accumulates in mutant cells deprived of adenine B protein abundance increases in response to DNA replication stress
170,396	171,703	-	gene	YAR018C	KIN3	KIN3,FUN52,NPK1,serine/threonine_protein_kinase_KIN3	sgd/S288C_reference_genome_R64-3-1_20210421	Nonessential serine/threonine protein kinase B possible role in DNA damage response B influences tolerance to high levels of ethanol

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BrentLab Yeast Genome Resources

This Dataset stores resources meant to make data exploration of yeast -omic data, curated by the Brent Lab, easier and more harmonious.
To cite, cite SGD

Usage

You may access just the Dataset metadata like this:

from huggingface_hub import ModelCard

card = ModelCard.load("BrentLab/yeast_genome_resources", repo_type="dataset")

# cast to dict
card_dict = card.data.to_dict()

# Get partition information
card_dict.get("dataset_info").get("partitioning").get("keys")

Output:

[{'name': 'chr',
  'dtype': 'string',
  'levels': 'chrI,chrII,chrVII,chrV,chrIII,chrIV,chrVIII,chrVI,chrX,chrIX,chrXI,chrXIV,chrXII,chrXIII,chrXV,chrXVI,chrM'}]

You can use this information to pull only the partition you're interested in, eg

from huggingface_hub import hf_hub_download

# Download a single partition file and store it in the local cache
local_file = hf_hub_download(
    repo_id="BrentLab/yeast_genome_resources",
    repo_type="dataset",
    filename="features/chr=chrII/part-0.parquet"
)

Dataset Details

Dataset Sources

Source: SGD S288C Reference Files
This is derived from S288C_reference_genome_R64-3-1_20210421.tgz

Dataset Structure

Features/

This is a Parquet dataset where the partitions are based on chr. Each row represents a genomic feature, and the columns are described below:

Field	Description
`chr`	Chromosome name (e.g., `chrI`, `chrII`, ..., `chrM`) in UCSC format
`start`	Start coordinate (1-based, inclusive)
`end`	End coordinate (1-based, inclusive)
`strand`	Strand: either `+` or `-`
`type`	Feature type — one of: `gene`, `ncRNA_gene`, `tRNA_gene`, `snoRNA_gene`, `transposable_element_gene`, `pseudogene`, `telomerase_RNA_gene`, `snRNA_gene`, `rRNA_gene`, `blocked_reading_frame`
`locus_tag`	Systematic gene identifier
`symbol`	Common name of the feature
`alias`	Alternate names (usually similar to `symbol`)
`source`	Origin or authority of the annotation
`note`	Description provided in the original GFF record

Dataset Author and Contact: Chase Mateusiak @cmatKhan

Downloads last month: 212

Size of downloaded dataset files:

1.2 MB

Size of the auto-converted Parquet files:

1.2 MB

Number of rows:

7,146

Collection including BrentLab/yeast_genome_resources

yeastresources

Collection

Data collected and harmonized for the Brent lab at Washington University • 10 items • Updated 11 days ago • 1