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NIFD_2_S_0007_MR_MT1__GradWarp__N3m_Br_20111229185843831_S133650_I274728 | On a T1-weighted brain MRI of a 65-year-old male subject, we observed:
For the cerebral cortex:
- no pathological changes consistent with atrophy detected in the occipital lobe
- focal atrophy of temporal lobe on temporal pole (between mild and moderate)
- focal atrophy of insular cortex on central operculum (mild)
- no pathological changes consistent with atrophy detected in the limbic cortex
- no pathological changes consistent with atrophy detected in the parietal lobe
- atrophies of frontal lobe on gyrus rectus (between mild and moderate) and lateral orbital gyrus (moderate)
For the subcortical structures:
- no pathological changes consistent with atrophy detected in the putamen
- between normal and mild atrophy of the thalamus
- no degenerative or atrophic changes noted in the basal forebrain
- pallidum presents with a healthy appearance, free from atrophy
- no signs of atrophy detected in the hippocampus
- the accumbens shows no structural abnormalities indicative of atrophy
- caudate presents with a healthy appearance, free from atrophy
- between normal and mild atrophy of the ventral dc
- between normal and mild atrophy of the amygdala
For the ventricles:
- 4th ventricle appears structurally intact, with no evidence of enlargement
- moderate bilateral lateral ventricle enlargement
- no pathological changes consistent with enlargement noted in the external csf
- between normal and mild enlargement of the inf. lateral ventricle
- 3rd ventricle maintains its normal volume without signs of enlargement | BV |
NIFD_1_S_0029_MR_t1_mprage_S4_DIS3D_br_raw_20110209101901199_30_S99286_I216392 | On a T1-weighted brain MRI of a 58-year-old female subject, we observed:
For the subcortical structures:
- moderate bilateral ventral dc atrophy
- severe bilateral caudate atrophy, more pronounced on the left
- severe bilateral pallidum atrophy, more pronounced on the left
- severe bilateral putamen atrophy, more pronounced on the left
- severe bilateral amygdala atrophy, more pronounced on the right
- moderate bilateral thalamus atrophy
- severe bilateral hippocampus atrophy, more pronounced on the right
- severe bilateral accumbens atrophy, more pronounced on the left
- no observable atrophic alterations in the basal forebrain
For the cerebral cortex:
- focal atrophy of temporal lobe on planum polare (between normal and mild)
- mild atrophy of the frontal lobe, with focal volume loss observed in the following subregions: gyrus rectus (mild), medial frontal cortex (between normal and mild) and sup. frontal gyrus (moderate)
- no pathological changes consistent with atrophy detected in the occipital lobe
- moderate bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe) and frontal operculum (moderate)
- moderate bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (severe)
- no signs of atrophy detected in the parietal lobe
For the ventricles:
- severe bilateral inf. lateral ventricle enlargement
- moderate bilateral lateral ventricle enlargement
- no observable enlargement or abnormal growth in the 4th ventricle
- external csf is free from enlargement or excessive growth
- moderate enlargement of the 3rd ventricle | BV |
NIFD_1_S_0209_MR_T1_mprage_S3_DIS3D_br_raw_20140901123615201_24_S229648_I442043 | On a T1-weighted brain MRI of a 58-year-old female subject, we observed:
For the cerebral cortex:
- moderate bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (moderate) and parahippocampal gyrus (between normal and mild)
- focal atrophy of temporal lobe on temporal pole (between mild and moderate)
- parietal lobe appears structurally intact with no atrophic changes
- atrophies of insular cortex on anterior insula (mild) and frontal operculum (between mild and moderate)
- occipital lobe appears structurally intact with no atrophic changes
- severe bilateral frontal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: frontal pole (mild), opercular inf. frontal gyrus (severe), orbital inf. frontal gyrus (between normal and mild), triangular inf. frontal gyrus (between moderate and severe), medial frontal cortex (mild), middle frontal gyrus (moderate), posterior orbital gyrus (between mild and moderate), sup. frontal gyrus (between moderate and severe) and sup. frontal gyrus medial segment (between normal and mild)
For the subcortical structures:
- ventral dc appears structurally intact with no atrophic changes
- between moderate and severe bilateral putamen atrophy, more pronounced on the right
- severe bilateral caudate atrophy
- between mild and moderate bilateral amygdala atrophy
- the basal forebrain shows no structural abnormalities indicative of atrophy
- the hippocampus shows no structural abnormalities indicative of atrophy
- mild bilateral thalamus atrophy
- between normal and mild right atrophy of the pallidum
- between mild and moderate bilateral accumbens atrophy
For the ventricles:
- moderate bilateral inf. lateral ventricle enlargement
- 4th ventricle remains within normal size parameters, with no enlargement detected
- between moderate and severe bilateral lateral ventricle enlargement
- between mild and moderate enlargement of the external csf
- severe enlargement of the 3rd ventricle | BV |
NIFD_2_S_0002_MR_MT1__GradWarp__N3m_Br_20111229184614074_S133938_I274719 | On a T1-weighted brain MRI of a 64-year-old male subject, we observed:
For the ventricles:
- severe enlargement of the 3rd ventricle
- between moderate and severe enlargement of the lateral ventricle, more pronounced on the right
- severe bilateral inf. lateral ventricle enlargement, more pronounced on the right
- 4th ventricle maintains its normal volume without signs of enlargement
- moderate enlargement of the external csf
For the subcortical structures:
- no degenerative or atrophic changes noted in the basal forebrain
- severe bilateral putamen atrophy, more pronounced on the right
- severe bilateral accumbens atrophy, more pronounced on the right
- no evidence of atrophy or degeneration in the amygdala
- severe bilateral pallidum atrophy, more pronounced on the right
- between normal and mild atrophy of the ventral dc, more pronounced on the right
- severe bilateral caudate atrophy, more pronounced on the right
- moderate atrophy of the thalamus, more pronounced on the right
- between mild and moderate atrophy of the hippocampus, more pronounced on the right
For the cerebral cortex:
- atrophies of temporal lobe on temporal pole (between normal and mild) and middle temporal gyrus (between normal and mild)
- the occipital lobe shows no structural abnormalities indicative of atrophy
- moderate atrophy of the limbic cortex, more pronounced on the right, with focal volume loss observed in the following subregions: anterior cingulate gyrus (severe)
- focal atrophy of parietal lobe on angular gyrus (between normal and mild)
- severe bilateral frontal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: frontal pole (severe), gyrus rectus (severe), opercular inf. frontal gyrus (moderate), medial frontal cortex (between mild and moderate), middle frontal gyrus (severe), anterior orbital gyrus (severe), lateral orbital gyrus (severe), medial orbital gyrus (between moderate and severe), posterior orbital gyrus (moderate), sup. frontal gyrus (between moderate and severe), sup. frontal gyrus medial segment (severe) and triangular inf. frontal gyrus (between normal and mild)
- severe atrophy of the insular cortex, more pronounced on the right, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (between normal and mild) and frontal operculum (between moderate and severe) | BV |
NIFD_1_S_0103_MR_T1_mprage_S3_DIS3D_br_raw_20120914122704384_3_S167579_I334274 | On a T1-weighted brain MRI of a 57-year-old female subject, we observed:
For the subcortical structures:
- between moderate and severe bilateral thalamus atrophy, more pronounced on the left
- no signs of atrophy detected in the basal forebrain
- severe bilateral pallidum atrophy, more pronounced on the left
- severe bilateral caudate atrophy, more pronounced on the left
- severe bilateral amygdala atrophy, more pronounced on the right
- ventral dc appears structurally intact with no atrophic changes
- severe bilateral accumbens atrophy
- severe bilateral putamen atrophy, more pronounced on the left
- moderate atrophy of the hippocampus, more pronounced on the right
For the ventricles:
- severe enlargement of the external csf
- 4th ventricle remains within normal size parameters, with no enlargement detected
- severe bilateral lateral ventricle enlargement
- severe enlargement of the 3rd ventricle
- severe bilateral inf. lateral ventricle enlargement
For the cerebral cortex:
- no observable atrophic alterations in the occipital lobe
- severe bilateral frontal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: frontal pole (between moderate and severe), gyrus rectus (severe), opercular inf. frontal gyrus (between mild and moderate), orbital inf. frontal gyrus (severe), medial frontal cortex (severe), middle frontal gyrus (moderate), anterior orbital gyrus (between mild and moderate), lateral orbital gyrus (severe), medial orbital gyrus (severe), posterior orbital gyrus (severe), subcallosal area (between mild and moderate), sup. frontal gyrus (moderate), sup. frontal gyrus medial segment (severe) and triangular inf. frontal gyrus (mild)
- no signs of atrophy detected in the parietal lobe
- severe bilateral temporal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: fusiform gyrus (mild), inf. temporal gyrus (severe), middle temporal gyrus (severe) and temporal pole (severe)
- severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (between mild and moderate), anterior cingulate gyrus (severe) and middle cingulate gyrus (mild)
- severe bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (severe) and frontal operculum (moderate) | BV |
NIFD_1_S_0096_MR_T1_mprage_S3_DIS3D_br_raw_20170817133934845_74_S598211_I891811 | On a T1-weighted brain MRI of a 69-year-old male subject, we observed:
For the subcortical structures:
- no signs of atrophy detected in the pallidum
- caudate appears structurally intact with no atrophic changes
- no evidence of atrophy or degeneration in the basal forebrain
- no signs of atrophy detected in the hippocampus
- no observable atrophic alterations in the accumbens
- amygdala presents with a healthy appearance, free from atrophy
- mild atrophy of the thalamus, more pronounced on the right
- no degenerative or atrophic changes noted in the putamen
- between normal and mild right atrophy of the ventral dc
For the cerebral cortex:
- between normal and mild atrophy of the insular cortex, with focal volume loss observed in the following subregions: frontal operculum (between mild and moderate)
- limbic cortex presents with a healthy appearance, free from atrophy
- no signs of atrophy detected in the temporal lobe
- focal atrophy of occipital lobe on occipital pole (between normal and mild)
- parietal lobe presents with a healthy appearance, free from atrophy
- focal atrophy of frontal lobe on middle frontal gyrus (mild)
For the ventricles:
- no abnormal enlargement observed in the lateral ventricle
- between mild and moderate enlargement of the 3rd ventricle
- the inf. lateral ventricle shows no structural abnormalities indicative of enlargement
- no signs of enlargement detected in the external csf
- no signs of enlargement detected in the 4th ventricle | BV |
NIFD_1_S_0333_MR_T1_mprage_S3_DIS3D_br_raw_20170628211504795_43_S577375_I866968 | On a T1-weighted brain MRI of a 65-year-old male subject, we observed:
For the cerebral cortex:
- focal atrophy of insular cortex on anterior insula (between moderate and severe)
- focal atrophy of temporal lobe on inf. temporal gyrus (between mild and moderate)
- severe atrophy of the frontal lobe, more pronounced on the right, with focal volume loss observed in the following subregions: gyrus rectus (moderate), middle frontal gyrus (moderate), posterior orbital gyrus (between normal and mild), sup. frontal gyrus (between moderate and severe) and sup. frontal gyrus medial segment (between moderate and severe)
- the parietal lobe shows no structural abnormalities indicative of atrophy
- mild atrophy of the limbic cortex, with focal volume loss observed in the following subregions: anterior cingulate gyrus (mild) and middle cingulate gyrus (between mild and moderate)
- no signs of atrophy detected in the occipital lobe
For the subcortical structures:
- no pathological changes consistent with atrophy detected in the accumbens
- no observable atrophic alterations in the basal forebrain
- between moderate and severe bilateral caudate atrophy, more pronounced on the right
- ventral dc appears structurally intact with no atrophic changes
- between normal and mild atrophy of the amygdala, more pronounced on the right
- thalamus remains normal, with no signs of tissue loss
- mild right atrophy of the pallidum
- hippocampus remains normal, with no signs of tissue loss
- moderate bilateral putamen atrophy, more pronounced on the right
For the ventricles:
- between normal and mild right enlargement of the lateral ventricle
- mild enlargement of the inf. lateral ventricle, more pronounced on the right
- no signs of enlargement detected in the 3rd ventricle
- no observable enlargement or abnormal growth in the 4th ventricle
- external csf maintains its normal volume without signs of enlargement | BV |
NIFD_2_S_0032_MR_MT1__GradWarp__N3m_Br_20130613083444087_S191547_I376358 | On a T1-weighted brain MRI of a 58-year-old male subject, we observed:
For the subcortical structures:
- no evidence of atrophy or degeneration in the putamen
- no signs of atrophy detected in the thalamus
- no evidence of atrophy or degeneration in the basal forebrain
- no pathological changes consistent with atrophy detected in the pallidum
- no evidence of atrophy or degeneration in the ventral dc
- accumbens remains normal, with no signs of tissue loss
- between moderate and severe bilateral hippocampus atrophy
- no evidence of atrophy or degeneration in the caudate
- mild atrophy of the amygdala
For the cerebral cortex:
- the parietal lobe shows no structural abnormalities indicative of atrophy
- focal atrophy of temporal lobe on inf. temporal gyrus (mild)
- focal atrophy of insular cortex on parietal operculum (between normal and mild)
- frontal lobe remains normal, with no signs of tissue loss
- limbic cortex maintains its normal morphology without atrophic features
- focal atrophy of occipital lobe on sup. occipital gyrus (between mild and moderate)
For the ventricles:
- lateral ventricle maintains its normal volume without signs of enlargement
- inf. lateral ventricle remains within normal size parameters, with no enlargement detected
- 3rd ventricle remains within normal size parameters, with no enlargement detected
- moderate enlargement of the external csf
- 4th ventricle appears structurally intact, with no evidence of enlargement | BV |
NIFD_2_S_0029_MR_MT1__GradWarp__N3m_Br_20130103113440420_S178016_I353168 | On a T1-weighted brain MRI of a 66-year-old male subject, we observed:
For the cerebral cortex:
- severe bilateral insular cortex atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (between normal and mild) and frontal operculum (moderate)
- parietal lobe remains normal, with no signs of tissue loss
- severe bilateral frontal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: frontal pole (between moderate and severe), gyrus rectus (severe), opercular inf. frontal gyrus (severe), orbital inf. frontal gyrus (severe), medial frontal cortex (severe), middle frontal gyrus (severe), anterior orbital gyrus (between moderate and severe), lateral orbital gyrus (severe), medial orbital gyrus (severe), posterior orbital gyrus (severe), precentral gyrus medial segment (moderate), subcallosal area (between moderate and severe), sup. frontal gyrus (between mild and moderate) and sup. frontal gyrus medial segment (severe)
- severe bilateral limbic cortex atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: entorhinal area (moderate) and anterior cingulate gyrus (severe)
- between moderate and severe atrophy of the temporal lobe, more pronounced on the left, with focal volume loss observed in the following subregions: middle temporal gyrus (moderate) and temporal pole (between moderate and severe)
- focal atrophy of occipital lobe on cuneus (mild)
For the subcortical structures:
- no signs of atrophy detected in the pallidum
- severe bilateral accumbens atrophy, more pronounced on the left
- no evidence of atrophy or degeneration in the thalamus
- no observable atrophic alterations in the ventral dc
- severe bilateral caudate atrophy, more pronounced on the left
- moderate atrophy of the putamen, more pronounced on the left
- the basal forebrain shows no structural abnormalities indicative of atrophy
- mild left atrophy of the hippocampus
- severe bilateral amygdala atrophy, more pronounced on the left
For the ventricles:
- severe bilateral lateral ventricle enlargement
- severe enlargement of the external csf
- no signs of enlargement detected in the 4th ventricle
- moderate enlargement of the 3rd ventricle
- severe bilateral inf. lateral ventricle enlargement, more pronounced on the left | BV |
NIFD_1_S_0005_MR_t1_mprage_S3_DIS3D_br_raw_20110414104256833_155_S104277_I227703 | On a T1-weighted brain MRI of a 59-year-old male subject, we observed:
For the subcortical structures:
- mild bilateral accumbens atrophy
- between moderate and severe bilateral thalamus atrophy
- between normal and mild bilateral ventral dc atrophy
- between normal and mild right atrophy of the amygdala
- severe bilateral pallidum atrophy
- hippocampus appears structurally intact with no atrophic changes
- basal forebrain presents with a healthy appearance, free from atrophy
- severe bilateral caudate atrophy
- moderate bilateral putamen atrophy
For the cerebral cortex:
- parietal lobe presents with a healthy appearance, free from atrophy
- focal atrophy of limbic cortex on entorhinal area (between mild and moderate)
- insular cortex maintains its normal morphology without atrophic features
- no pathological changes consistent with atrophy detected in the occipital lobe
- between normal and mild atrophy of the temporal lobe, more pronounced on the right, with focal volume loss observed in the following subregions: planum polare (moderate)
- focal atrophy of frontal lobe on anterior orbital gyrus (moderate)
For the ventricles:
- mild enlargement of the inf. lateral ventricle, more pronounced on the right
- between normal and mild enlargement of the external csf
- 3rd ventricle remains within normal size parameters, with no enlargement detected
- mild right enlargement of the lateral ventricle
- no observable enlargement or abnormal growth in the 4th ventricle | BV |
NIFD_2_S_0021_MR_MT1__GradWarp__N3m_Br_20130114173911629_S160243_I355049 | On a T1-weighted brain MRI of a 60-year-old male subject, we observed:
For the ventricles:
- no abnormal enlargement observed in the external csf
- no abnormal enlargement observed in the 3rd ventricle
- between normal and mild enlargement of the 4th ventricle
- inf. lateral ventricle is free from enlargement or excessive growth
- lateral ventricle maintains its normal volume without signs of enlargement
For the cerebral cortex:
- no degenerative or atrophic changes noted in the parietal lobe
- focal atrophy of frontal lobe on opercular inf. frontal gyrus (moderate)
- atrophies of limbic cortex on middle cingulate gyrus (mild) and posterior cingulate gyrus (between normal and mild)
- focal atrophy of insular cortex on parietal operculum (between normal and mild)
- temporal lobe remains normal, with no signs of tissue loss
- occipital lobe maintains its normal morphology without atrophic features
For the subcortical structures:
- no signs of atrophy detected in the amygdala
- caudate presents with a healthy appearance, free from atrophy
- no observable atrophic alterations in the pallidum
- ventral dc presents with a healthy appearance, free from atrophy
- no degenerative or atrophic changes noted in the putamen
- no signs of atrophy detected in the basal forebrain
- no evidence of atrophy or degeneration in the hippocampus
- accumbens remains normal, with no signs of tissue loss
- no evidence of atrophy or degeneration in the thalamus | BV |
NIFD_1_S_0018_MR_t1_mprage__br_raw_20170814165807711_159_S594325_I886781 | On a T1-weighted brain MRI of a 71-year-old male subject, we observed:
For the ventricles:
- 4th ventricle remains within normal size parameters, with no enlargement detected
- 3rd ventricle remains within normal size parameters, with no enlargement detected
- lateral ventricle is free from enlargement or excessive growth
- severe bilateral inf. lateral ventricle enlargement
- severe enlargement of the external csf
For the cerebral cortex:
- focal atrophy of insular cortex on anterior insula (between normal and mild)
- no signs of atrophy detected in the occipital lobe
- moderate atrophy of the limbic cortex, more pronounced on the left, with focal volume loss observed in the following subregions: entorhinal area (between moderate and severe) and anterior cingulate gyrus (mild)
- mild atrophy of the parietal lobe, with focal volume loss observed in the following subregions: precuneus (between normal and mild) and sup. parietal lobule (moderate)
- focal atrophy of frontal lobe on subcallosal area (mild)
- severe bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: inf. temporal gyrus (severe), middle temporal gyrus (severe) and temporal pole (severe)
For the subcortical structures:
- between moderate and severe bilateral hippocampus atrophy
- between normal and mild right atrophy of the ventral dc
- between moderate and severe bilateral thalamus atrophy, more pronounced on the right
- severe bilateral amygdala atrophy, more pronounced on the left
- basal forebrain maintains its normal morphology without atrophic features
- no observable atrophic alterations in the putamen
- moderate bilateral accumbens atrophy, more pronounced on the right
- pallidum remains normal, with no signs of tissue loss
- mild left atrophy of the caudate | BV |
NIFD_3_S_0005_MR_t1_mprage_ND_br_raw_20160518200000281_123_S442841_I709843 | On a T1-weighted brain MRI of a 63-year-old male subject, we observed:
For the ventricles:
- 4th ventricle maintains its normal volume without signs of enlargement
- the 3rd ventricle shows no structural abnormalities indicative of enlargement
- no pathological changes consistent with enlargement noted in the lateral ventricle
- no observable enlargement or abnormal growth in the inf. lateral ventricle
- external csf is free from enlargement or excessive growth
For the cerebral cortex:
- focal atrophy of temporal lobe on planum temporale (moderate)
- focal atrophy of occipital lobe on lingual gyrus (moderate)
- atrophies of frontal lobe on gyrus rectus (between mild and moderate), triangular inf. frontal gyrus (between mild and moderate) and medial frontal cortex (between normal and mild)
- no degenerative or atrophic changes noted in the insular cortex
- between mild and moderate atrophy of the parietal lobe, more pronounced on the left, with focal volume loss observed in the following subregions: postcentral gyrus medial segment (mild)
- mild atrophy of the limbic cortex, with focal volume loss observed in the following subregions: entorhinal area (between mild and moderate) and parahippocampal gyrus (between normal and mild)
For the subcortical structures:
- no evidence of atrophy or degeneration in the pallidum
- no pathological changes consistent with atrophy detected in the putamen
- no observable atrophic alterations in the basal forebrain
- no degenerative or atrophic changes noted in the hippocampus
- no evidence of atrophy or degeneration in the ventral dc
- no pathological changes consistent with atrophy detected in the thalamus
- no evidence of atrophy or degeneration in the amygdala
- no pathological changes consistent with atrophy detected in the accumbens
- caudate maintains its normal morphology without atrophic features | BV |
NIFD_2_S_0027_MR_MT1__GradWarp__N3m_Br_20130103113648528_S177998_I353170 | On a T1-weighted brain MRI of a 58-year-old female subject, we observed:
For the subcortical structures:
- between mild and moderate bilateral putamen atrophy
- no evidence of atrophy or degeneration in the basal forebrain
- caudate remains normal, with no signs of tissue loss
- no pathological changes consistent with atrophy detected in the ventral dc
- between mild and moderate bilateral pallidum atrophy
- severe bilateral hippocampus atrophy, more pronounced on the left
- severe bilateral amygdala atrophy
- between mild and moderate atrophy of the accumbens, more pronounced on the right
- thalamus appears structurally intact with no atrophic changes
For the ventricles:
- severe enlargement of the external csf
- no pathological changes consistent with enlargement noted in the 3rd ventricle
- no enlargement observed in the lateral ventricle
- mild enlargement of the 4th ventricle
- between normal and mild enlargement of the inf. lateral ventricle, more pronounced on the left
For the cerebral cortex:
- severe bilateral temporal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: fusiform gyrus (moderate), middle temporal gyrus (moderate), sup. temporal gyrus (between normal and mild) and temporal pole (severe)
- focal atrophy of occipital lobe on cuneus (between normal and mild)
- moderate bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe) and posterior insula (between normal and mild)
- no pathological changes consistent with atrophy detected in the parietal lobe
- between moderate and severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (severe) and parahippocampal gyrus (severe)
- atrophies of frontal lobe on lateral orbital gyrus (moderate) and opercular inf. frontal gyrus (between normal and mild) | BV |
NIFD_1_S_0085_MR_T1_mprage_S3_DIS3D_br_raw_20120307000133150_31_S143023_I288641 | On a T1-weighted brain MRI of a 47-year-old female subject, we observed:
For the cerebral cortex:
- limbic cortex presents with a healthy appearance, free from atrophy
- focal atrophy of temporal lobe on temporal pole (between moderate and severe)
- no observable atrophic alterations in the insular cortex
- focal atrophy of parietal lobe on precuneus (between normal and mild)
- mild atrophy of the frontal lobe, more pronounced on the left, with focal volume loss observed in the following subregions: middle frontal gyrus (between moderate and severe), lateral orbital gyrus (between normal and mild) and sup. frontal gyrus medial segment (between normal and mild)
- occipital lobe remains normal, with no signs of tissue loss
For the subcortical structures:
- between moderate and severe bilateral hippocampus atrophy
- no pathological changes consistent with atrophy detected in the accumbens
- between moderate and severe atrophy of the thalamus, more pronounced on the left
- between normal and mild atrophy of the caudate, more pronounced on the left
- between normal and mild left atrophy of the amygdala
- between normal and mild left atrophy of the putamen
- basal forebrain remains normal, with no signs of tissue loss
- mild atrophy of the pallidum, more pronounced on the left
- between normal and mild atrophy of the ventral dc, more pronounced on the left
For the ventricles:
- no signs of enlargement detected in the lateral ventricle
- moderate enlargement of the 3rd ventricle
- inf. lateral ventricle maintains its normal volume without signs of enlargement
- 4th ventricle remains within normal size parameters, with no enlargement detected
- severe enlargement of the external csf | BV |
NIFD_1_S_0056_MR_t1_mprage_S3_DIS3D_br_raw_20111019194910586_85_S125860_I261681 | On a T1-weighted brain MRI of a 59-year-old male subject, we observed:
For the subcortical structures:
- no degenerative or atrophic changes noted in the putamen
- between mild and moderate atrophy of the hippocampus
- severe bilateral thalamus atrophy, more pronounced on the left
- moderate bilateral accumbens atrophy
- between mild and moderate bilateral pallidum atrophy
- moderate bilateral caudate atrophy, more pronounced on the left
- basal forebrain remains normal, with no signs of tissue loss
- moderate bilateral amygdala atrophy
- between normal and mild atrophy of the ventral dc, more pronounced on the left
For the cerebral cortex:
- mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: gyrus rectus (mild), posterior orbital gyrus (between mild and moderate) and sup. frontal gyrus (between moderate and severe)
- atrophies of insular cortex on central operculum (between normal and mild) and parietal operculum (between moderate and severe)
- moderate atrophy of the parietal lobe, with focal volume loss observed in the following subregions: precuneus (between mild and moderate) and supramarginal gyrus (mild)
- focal atrophy of temporal lobe on planum polare (mild)
- no signs of atrophy detected in the occipital lobe
- focal atrophy of limbic cortex on anterior cingulate gyrus (between normal and mild)
For the ventricles:
- moderate bilateral inf. lateral ventricle enlargement
- external csf is free from enlargement or excessive growth
- no abnormal enlargement observed in the 3rd ventricle
- 4th ventricle appears structurally intact, with no evidence of enlargement
- severe bilateral lateral ventricle enlargement | BV |
NIFD_2_S_0004_MR_MT1__GradWarp__N3m_Br_20120105162046732_S133219_I275501 | On a T1-weighted brain MRI of a 66-year-old male subject, we observed:
For the ventricles:
- between moderate and severe bilateral lateral ventricle enlargement
- moderate enlargement of the external csf
- between moderate and severe enlargement of the 3rd ventricle
- severe bilateral inf. lateral ventricle enlargement
- the 4th ventricle shows no structural abnormalities indicative of enlargement
For the cerebral cortex:
- parietal lobe remains normal, with no signs of tissue loss
- severe bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: fusiform gyrus (between moderate and severe), planum polare (moderate), inf. temporal gyrus (severe), middle temporal gyrus (mild) and temporal pole (severe)
- moderate bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: gyrus rectus (severe), medial frontal cortex (between moderate and severe), middle frontal gyrus (moderate), medial orbital gyrus (between moderate and severe) and subcallosal area (mild)
- occipital lobe presents with a healthy appearance, free from atrophy
- severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (severe), anterior cingulate gyrus (between moderate and severe), middle cingulate gyrus (moderate) and parahippocampal gyrus (severe)
- severe bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (severe) and frontal operculum (between mild and moderate)
For the subcortical structures:
- the basal forebrain shows no structural abnormalities indicative of atrophy
- severe bilateral hippocampus atrophy
- severe bilateral amygdala atrophy, more pronounced on the left
- severe bilateral accumbens atrophy
- between normal and mild left atrophy of the caudate
- no evidence of atrophy or degeneration in the ventral dc
- between normal and mild atrophy of the thalamus
- moderate bilateral pallidum atrophy
- severe bilateral putamen atrophy | BV |
NIFD_1_S_0040_MR_t1_mprage_S3_DIS3D_br_raw_20150522131343256_7_S261234_I494492 | On a T1-weighted brain MRI of a 71-year-old female subject, we observed:
For the cerebral cortex:
- severe bilateral frontal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: frontal pole (severe), gyrus rectus (severe), opercular inf. frontal gyrus (between moderate and severe), triangular inf. frontal gyrus (severe), medial frontal cortex (moderate), middle frontal gyrus (severe), lateral orbital gyrus (between mild and moderate), medial orbital gyrus (moderate), posterior orbital gyrus (moderate), sup. frontal gyrus (between moderate and severe), sup. frontal gyrus medial segment (moderate) and precentral gyrus (mild)
- severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (severe), middle cingulate gyrus (moderate), posterior cingulate gyrus (between normal and mild) and parahippocampal gyrus (between normal and mild)
- occipital lobe presents with a healthy appearance, free from atrophy
- severe bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (mild), frontal operculum (moderate) and parietal operculum (moderate)
- focal atrophy of parietal lobe on precuneus (between normal and mild)
- atrophies of temporal lobe on planum polare (between normal and mild) and sup. temporal gyrus (between normal and mild)
For the subcortical structures:
- severe bilateral caudate atrophy, more pronounced on the left
- severe bilateral accumbens atrophy, more pronounced on the left
- severe bilateral putamen atrophy, more pronounced on the left
- between moderate and severe bilateral amygdala atrophy
- no observable atrophic alterations in the basal forebrain
- severe bilateral thalamus atrophy, more pronounced on the left
- mild atrophy of the hippocampus, more pronounced on the left
- severe bilateral pallidum atrophy, more pronounced on the left
- moderate bilateral ventral dc atrophy
For the ventricles:
- moderate enlargement of the 3rd ventricle
- severe bilateral inf. lateral ventricle enlargement, more pronounced on the left
- severe bilateral lateral ventricle enlargement
- the 4th ventricle shows no structural abnormalities indicative of enlargement
- severe enlargement of the external csf | BV |
NIFD_1_S_0130_MR_T1_mprage_S3_DIS3D_br_raw_20130719163246403_84_S195891_I381770 | On a T1-weighted brain MRI of a 58-year-old male subject, we observed:
For the cerebral cortex:
- focal atrophy of temporal lobe on planum temporale (between normal and mild)
- between moderate and severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (moderate)
- mild atrophy of the insular cortex, more pronounced on the left, with focal volume loss observed in the following subregions: anterior insula (severe)
- focal atrophy of occipital lobe on occipital fusiform gyrus (mild)
- the parietal lobe shows no structural abnormalities indicative of atrophy
- focal atrophy of frontal lobe on middle frontal gyrus (between normal and mild)
For the subcortical structures:
- severe bilateral caudate atrophy, more pronounced on the left
- between normal and mild left atrophy of the accumbens
- moderate bilateral amygdala atrophy
- moderate atrophy of the thalamus, more pronounced on the left
- severe bilateral putamen atrophy, more pronounced on the left
- basal forebrain presents with a healthy appearance, free from atrophy
- between normal and mild atrophy of the ventral dc, more pronounced on the left
- between mild and moderate bilateral hippocampus atrophy
- between moderate and severe bilateral pallidum atrophy, more pronounced on the left
For the ventricles:
- severe bilateral inf. lateral ventricle enlargement, more pronounced on the left
- between mild and moderate enlargement of the external csf
- between moderate and severe enlargement of the 3rd ventricle
- between moderate and severe enlargement of the lateral ventricle, more pronounced on the left
- 4th ventricle remains within normal size parameters, with no enlargement detected | BV |
NIFD_1_S_0081_MR_T1_mprage_S3_DIS3D_br_raw_20120307021952212_143_S143093_I288731 | On a T1-weighted brain MRI of a 60-year-old male subject, we observed:
For the subcortical structures:
- between moderate and severe bilateral caudate atrophy, more pronounced on the right
- moderate bilateral putamen atrophy, more pronounced on the right
- the amygdala shows no structural abnormalities indicative of atrophy
- between mild and moderate atrophy of the pallidum, more pronounced on the right
- basal forebrain maintains its normal morphology without atrophic features
- no pathological changes consistent with atrophy detected in the ventral dc
- mild bilateral accumbens atrophy
- no degenerative or atrophic changes noted in the hippocampus
- no evidence of atrophy or degeneration in the thalamus
For the ventricles:
- severe enlargement of the external csf
- mild enlargement of the inf. lateral ventricle
- 4th ventricle remains within normal size parameters, with no enlargement detected
- mild right enlargement of the lateral ventricle
- 3rd ventricle is free from enlargement or excessive growth
For the cerebral cortex:
- focal atrophy of insular cortex on frontal operculum (between mild and moderate)
- no pathological changes consistent with atrophy detected in the occipital lobe
- no degenerative or atrophic changes noted in the temporal lobe
- moderate atrophy of the frontal lobe, more pronounced on the right, with focal volume loss observed in the following subregions: middle frontal gyrus (between normal and mild), posterior orbital gyrus (moderate), sup. frontal gyrus (between normal and mild) and opercular inf. frontal gyrus (mild)
- focal atrophy of limbic cortex on anterior cingulate gyrus (moderate)
- parietal lobe appears structurally intact with no atrophic changes | BV |
NIFD_1_S_0102_MR_T1_mprage_S3_DIS3D_br_raw_20170816161439198_36_S596667_I889712 | On a T1-weighted brain MRI of a 71-year-old male subject, we observed:
For the ventricles:
- between mild and moderate enlargement of the 3rd ventricle
- between mild and moderate left enlargement of the lateral ventricle
- no pathological changes consistent with enlargement noted in the 4th ventricle
- severe enlargement of the external csf
- the inf. lateral ventricle shows no structural abnormalities indicative of enlargement
For the subcortical structures:
- severe bilateral caudate atrophy, more pronounced on the left
- between normal and mild atrophy of the amygdala
- severe bilateral pallidum atrophy, more pronounced on the left
- severe bilateral ventral dc atrophy, more pronounced on the left
- mild atrophy of the basal forebrain, more pronounced on the left
- severe bilateral putamen atrophy, more pronounced on the left
- between normal and mild left atrophy of the accumbens
- between mild and moderate bilateral hippocampus atrophy
- severe bilateral thalamus atrophy, more pronounced on the left
For the cerebral cortex:
- mild atrophy of the limbic cortex, more pronounced on the left, with focal volume loss observed in the following subregions: anterior cingulate gyrus (moderate) and middle cingulate gyrus (mild)
- no observable atrophic alterations in the occipital lobe
- no evidence of atrophy or degeneration in the temporal lobe
- severe bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (moderate), gyrus rectus (between mild and moderate), middle frontal gyrus (severe), precentral gyrus (severe), sup. frontal gyrus (between mild and moderate) and supplementary motor cortex (moderate)
- atrophies of insular cortex on anterior insula (moderate) and frontal operculum (mild)
- focal atrophy of parietal lobe on angular gyrus (between normal and mild) | BV |
NIFD_1_S_0119_MR_t1_mprage_S3_DIS3D_br_raw_20170814185756776_15_S594508_I887000 | On a T1-weighted brain MRI of a 70-year-old female subject, we observed:
For the subcortical structures:
- mild bilateral putamen atrophy
- between moderate and severe bilateral pallidum atrophy
- mild bilateral amygdala atrophy
- moderate atrophy of the basal forebrain, more pronounced on the left
- moderate bilateral thalamus atrophy
- moderate bilateral ventral dc atrophy
- no degenerative or atrophic changes noted in the accumbens
- between mild and moderate atrophy of the hippocampus
- between mild and moderate bilateral caudate atrophy
For the cerebral cortex:
- focal atrophy of insular cortex on anterior insula (between mild and moderate)
- atrophies of parietal lobe on postcentral gyrus (moderate) and precuneus (between normal and mild)
- mild atrophy of the temporal lobe, with focal volume loss observed in the following subregions: fusiform gyrus (between normal and mild)
- mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: middle frontal gyrus (mild), precentral gyrus (between mild and moderate) and sup. frontal gyrus medial segment (mild)
- occipital lobe maintains its normal morphology without atrophic features
- the limbic cortex shows no structural abnormalities indicative of atrophy
For the ventricles:
- no signs of enlargement detected in the lateral ventricle
- inf. lateral ventricle is free from enlargement or excessive growth
- between mild and moderate enlargement of the external csf
- 4th ventricle maintains its normal volume without signs of enlargement
- 3rd ventricle appears structurally intact, with no evidence of enlargement | BV |
NIFD_1_S_0332_MR_t1_mprage_short__br_raw_20170628200022329_22_S577253_I866807 | On a T1-weighted brain MRI of a 55-year-old male subject, we observed:
For the ventricles:
- mild enlargement of the lateral ventricle
- severe enlargement of the 4th ventricle
- severe bilateral inf. lateral ventricle enlargement
- between mild and moderate enlargement of the external csf
- moderate enlargement of the 3rd ventricle
For the cerebral cortex:
- between mild and moderate bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: postcentral gyrus medial segment (moderate) and sup. parietal lobule (between mild and moderate)
- atrophies of frontal lobe on middle frontal gyrus (between normal and mild) and sup. frontal gyrus medial segment (between normal and mild)
- atrophies of temporal lobe on planum polare (between mild and moderate) and middle temporal gyrus (between normal and mild)
- moderate bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (between mild and moderate) and anterior cingulate gyrus (between mild and moderate)
- focal atrophy of occipital lobe on inf. occipital gyrus (mild)
- the insular cortex shows no structural abnormalities indicative of atrophy
For the subcortical structures:
- no observable atrophic alterations in the amygdala
- no signs of atrophy detected in the thalamus
- moderate bilateral pallidum atrophy
- moderate bilateral putamen atrophy
- severe bilateral accumbens atrophy, more pronounced on the right
- the hippocampus shows no structural abnormalities indicative of atrophy
- moderate bilateral caudate atrophy
- no observable atrophic alterations in the ventral dc
- no signs of atrophy detected in the basal forebrain | BV |
NIFD_2_S_0030_MR_MT1__GradWarp__N3m_Br_20130111113347184_S179870_I354749 | On a T1-weighted brain MRI of a 65-year-old male subject, we observed:
For the subcortical structures:
- no signs of atrophy detected in the basal forebrain
- between normal and mild atrophy of the hippocampus, more pronounced on the left
- between moderate and severe atrophy of the amygdala, more pronounced on the left
- no pathological changes consistent with atrophy detected in the ventral dc
- severe bilateral putamen atrophy, more pronounced on the left
- between mild and moderate left atrophy of the thalamus
- severe bilateral caudate atrophy, more pronounced on the left
- mild left atrophy of the pallidum
- severe bilateral accumbens atrophy, more pronounced on the left
For the cerebral cortex:
- occipital lobe remains normal, with no signs of tissue loss
- no pathological changes consistent with atrophy detected in the parietal lobe
- focal atrophy of limbic cortex on anterior cingulate gyrus (severe)
- between moderate and severe bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (moderate) and frontal operculum (moderate)
- between moderate and severe bilateral temporal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: fusiform gyrus (between normal and mild), middle temporal gyrus (mild) and sup. temporal gyrus (between mild and moderate)
- severe bilateral frontal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: frontal pole (between moderate and severe), gyrus rectus (mild), opercular inf. frontal gyrus (between mild and moderate), triangular inf. frontal gyrus (mild), medial frontal cortex (between mild and moderate), middle frontal gyrus (severe), lateral orbital gyrus (moderate), medial orbital gyrus (severe), sup. frontal gyrus (severe) and supplementary motor cortex (moderate)
For the ventricles:
- no enlargement observed in the lateral ventricle
- moderate enlargement of the inf. lateral ventricle, more pronounced on the left
- severe enlargement of the external csf
- no signs of enlargement detected in the 4th ventricle
- between normal and mild enlargement of the 3rd ventricle | BV |
NIFD_1_S_0039_MR_t1_mprage_S9_DIS3D_br_raw_20110422210646858_48_S105044_I228811 | On a T1-weighted brain MRI of a 67-year-old male subject, we observed:
For the ventricles:
- severe enlargement of the external csf
- no signs of enlargement detected in the 3rd ventricle
- severe bilateral inf. lateral ventricle enlargement, more pronounced on the right
- severe bilateral lateral ventricle enlargement
- 4th ventricle is free from enlargement or excessive growth
For the cerebral cortex:
- severe bilateral limbic cortex atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: entorhinal area (moderate), anterior cingulate gyrus (severe) and middle cingulate gyrus (between mild and moderate)
- focal atrophy of parietal lobe on angular gyrus (mild)
- no evidence of atrophy or degeneration in the occipital lobe
- severe bilateral insular cortex atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (severe) and frontal operculum (moderate)
- severe bilateral frontal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: frontal pole (severe), gyrus rectus (severe), opercular inf. frontal gyrus (severe), orbital inf. frontal gyrus (moderate), triangular inf. frontal gyrus (between moderate and severe), medial frontal cortex (between moderate and severe), middle frontal gyrus (severe), anterior orbital gyrus (severe), lateral orbital gyrus (severe), medial orbital gyrus (severe), posterior orbital gyrus (severe), precentral gyrus (between mild and moderate), sup. frontal gyrus (severe), sup. frontal gyrus medial segment (severe) and supplementary motor cortex (moderate)
- temporal lobe presents with a healthy appearance, free from atrophy
For the subcortical structures:
- severe bilateral amygdala atrophy, more pronounced on the right
- severe bilateral accumbens atrophy, more pronounced on the right
- severe bilateral caudate atrophy, more pronounced on the right
- mild right atrophy of the ventral dc
- between moderate and severe atrophy of the pallidum, more pronounced on the right
- no observable atrophic alterations in the basal forebrain
- severe bilateral hippocampus atrophy, more pronounced on the right
- severe bilateral putamen atrophy, more pronounced on the right
- moderate atrophy of the thalamus, more pronounced on the right | BV |
NIFD_2_S_0014_MR_MT1__GradWarp__N3m_Br_20111229191004875_S134530_I274739 | On a T1-weighted brain MRI of a 53-year-old male subject, we observed:
For the subcortical structures:
- between normal and mild atrophy of the thalamus
- moderate bilateral amygdala atrophy
- severe bilateral caudate atrophy
- ventral dc appears structurally intact with no atrophic changes
- between moderate and severe bilateral putamen atrophy
- severe bilateral pallidum atrophy
- between normal and mild right atrophy of the hippocampus
- severe bilateral accumbens atrophy, more pronounced on the left
- no pathological changes consistent with atrophy detected in the basal forebrain
For the cerebral cortex:
- between normal and mild atrophy of the temporal lobe, more pronounced on the right, with focal volume loss observed in the following subregions: sup. temporal gyrus (between mild and moderate) and temporal pole (mild)
- severe bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: gyrus rectus (between mild and moderate), opercular inf. frontal gyrus (between normal and mild), middle frontal gyrus (between mild and moderate), lateral orbital gyrus (mild), posterior orbital gyrus (severe) and sup. frontal gyrus (between mild and moderate)
- between normal and mild atrophy of the limbic cortex, with focal volume loss observed in the following subregions: anterior cingulate gyrus (between mild and moderate)
- atrophies of occipital lobe on cuneus (between mild and moderate) and middle occipital gyrus (between mild and moderate)
- severe bilateral insular cortex atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: anterior insula (between moderate and severe), central operculum (between moderate and severe) and parietal operculum (between normal and mild)
- severe bilateral parietal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: angular gyrus (between normal and mild), precuneus (between normal and mild), sup. parietal lobule (between moderate and severe) and supramarginal gyrus (moderate)
For the ventricles:
- severe bilateral inf. lateral ventricle enlargement
- severe enlargement of the external csf
- severe enlargement of the 4th ventricle
- moderate enlargement of the 3rd ventricle
- severe bilateral lateral ventricle enlargement | BV |
NIFD_1_S_0032_MR_t1_mprage_S41_DIS3D__br_raw_20110514204129592_155_S108946_I235070 | On a T1-weighted brain MRI of a 60-year-old male subject, we observed:
For the ventricles:
- 4th ventricle remains within normal size parameters, with no enlargement detected
- between normal and mild enlargement of the lateral ventricle
- severe enlargement of the external csf
- no enlargement observed in the 3rd ventricle
- mild left enlargement of the inf. lateral ventricle
For the subcortical structures:
- mild left atrophy of the caudate
- between moderate and severe bilateral accumbens atrophy, more pronounced on the left
- mild atrophy of the hippocampus, more pronounced on the left
- moderate bilateral amygdala atrophy, more pronounced on the left
- between normal and mild atrophy of the putamen, more pronounced on the left
- moderate bilateral ventral dc atrophy, more pronounced on the left
- between moderate and severe bilateral pallidum atrophy, more pronounced on the left
- basal forebrain appears structurally intact with no atrophic changes
- between mild and moderate atrophy of the thalamus, more pronounced on the left
For the cerebral cortex:
- severe bilateral frontal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: opercular inf. frontal gyrus (mild), middle frontal gyrus (severe), posterior orbital gyrus (mild), precentral gyrus (between moderate and severe) and orbital inf. frontal gyrus (between normal and mild)
- between mild and moderate atrophy of the insular cortex, with focal volume loss observed in the following subregions: anterior insula (severe) and frontal operculum (between normal and mild)
- focal atrophy of temporal lobe on temporal pole (between moderate and severe)
- focal atrophy of occipital lobe on cuneus (moderate)
- between mild and moderate atrophy of the limbic cortex, with focal volume loss observed in the following subregions: anterior cingulate gyrus (between moderate and severe) and middle cingulate gyrus (mild)
- no observable atrophic alterations in the parietal lobe | BV |
NIFD_1_S_0091_MR_T1_mprage_S3_DIS3D_br_raw_20170817104021048_43_S597455_I890811 | On a T1-weighted brain MRI of a 57-year-old male subject, we observed:
For the ventricles:
- no enlargement observed in the external csf
- mild right enlargement of the lateral ventricle
- between normal and mild enlargement of the 3rd ventricle
- no signs of enlargement detected in the 4th ventricle
- no abnormal enlargement observed in the inf. lateral ventricle
For the subcortical structures:
- no signs of atrophy detected in the putamen
- pallidum presents with a healthy appearance, free from atrophy
- no pathological changes consistent with atrophy detected in the basal forebrain
- no observable atrophic alterations in the ventral dc
- caudate remains normal, with no signs of tissue loss
- no degenerative or atrophic changes noted in the accumbens
- no degenerative or atrophic changes noted in the hippocampus
- no signs of atrophy detected in the amygdala
- severe bilateral thalamus atrophy
For the cerebral cortex:
- occipital lobe presents with a healthy appearance, free from atrophy
- atrophies of frontal lobe on anterior orbital gyrus (moderate) and posterior orbital gyrus (between normal and mild)
- severe bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: posterior insula (severe), central operculum (between normal and mild) and parietal operculum (moderate)
- atrophies of limbic cortex on entorhinal area (between normal and mild) and posterior cingulate gyrus (moderate)
- focal atrophy of parietal lobe on postcentral gyrus (between normal and mild)
- atrophies of temporal lobe on planum temporale (mild) and transverse temporal gyrus (mild) | BV |
NIFD_1_S_0095_MR_T1_mprage_S3_DIS3D_br_raw_20120819163606804_114_S161475_I324728 | On a T1-weighted brain MRI of a 73-year-old female subject, we observed:
For the cerebral cortex:
- mild atrophy of the insular cortex, with focal volume loss observed in the following subregions: anterior insula (between mild and moderate)
- the temporal lobe shows no structural abnormalities indicative of atrophy
- severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (between mild and moderate), anterior cingulate gyrus (between moderate and severe) and parahippocampal gyrus (between mild and moderate)
- severe bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (moderate), gyrus rectus (moderate), opercular inf. frontal gyrus (between normal and mild), orbital inf. frontal gyrus (moderate), triangular inf. frontal gyrus (between normal and mild), medial frontal cortex (moderate), middle frontal gyrus (severe), anterior orbital gyrus (between normal and mild), medial orbital gyrus (moderate), sup. frontal gyrus (between normal and mild) and sup. frontal gyrus medial segment (between mild and moderate)
- no signs of atrophy detected in the parietal lobe
- atrophies of occipital lobe on calcarine cortex (between normal and mild) and occipital pole (between mild and moderate)
For the ventricles:
- no observable enlargement or abnormal growth in the 4th ventricle
- severe enlargement of the 3rd ventricle
- severe bilateral lateral ventricle enlargement
- severe bilateral inf. lateral ventricle enlargement
- external csf appears structurally intact, with no evidence of enlargement
For the subcortical structures:
- severe bilateral amygdala atrophy, more pronounced on the left
- between moderate and severe bilateral thalamus atrophy
- moderate bilateral hippocampus atrophy, more pronounced on the right
- severe bilateral caudate atrophy
- severe bilateral accumbens atrophy, more pronounced on the left
- moderate bilateral pallidum atrophy, more pronounced on the left
- the ventral dc shows no structural abnormalities indicative of atrophy
- no pathological changes consistent with atrophy detected in the basal forebrain
- severe bilateral putamen atrophy | BV |
NIFD_1_S_0322_MR_t1_mprage__br_raw_20170628162001259_142_S576863_I866324 | On a T1-weighted brain MRI of a 45-year-old male subject, we observed:
For the ventricles:
- between normal and mild enlargement of the 3rd ventricle
- mild enlargement of the external csf
- no pathological changes consistent with enlargement noted in the 4th ventricle
- severe bilateral lateral ventricle enlargement
- severe bilateral inf. lateral ventricle enlargement, more pronounced on the left
For the cerebral cortex:
- no signs of atrophy detected in the parietal lobe
- focal atrophy of limbic cortex on anterior cingulate gyrus (moderate)
- mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: central operculum (between mild and moderate) and frontal operculum (mild)
- focal atrophy of temporal lobe on transverse temporal gyrus (between normal and mild)
- atrophies of occipital lobe on cuneus (mild) and occipital pole (between mild and moderate)
- severe bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (between moderate and severe), opercular inf. frontal gyrus (mild), middle frontal gyrus (between moderate and severe), anterior orbital gyrus (mild), precentral gyrus (between mild and moderate), sup. frontal gyrus (moderate) and sup. frontal gyrus medial segment (severe)
For the subcortical structures:
- the ventral dc shows no structural abnormalities indicative of atrophy
- moderate bilateral thalamus atrophy
- between normal and mild left atrophy of the hippocampus
- amygdala maintains its normal morphology without atrophic features
- no evidence of atrophy or degeneration in the basal forebrain
- moderate bilateral putamen atrophy, more pronounced on the left
- between normal and mild left atrophy of the accumbens
- between moderate and severe bilateral caudate atrophy, more pronounced on the left
- between mild and moderate bilateral pallidum atrophy | BV |
NIFD_1_S_0324_MR_t1_mprage__br_raw_20170628163333846_44_S576938_I866414 | On a T1-weighted brain MRI of a 58-year-old male subject, we observed:
For the subcortical structures:
- ventral dc maintains its normal morphology without atrophic features
- basal forebrain maintains its normal morphology without atrophic features
- pallidum appears structurally intact with no atrophic changes
- severe bilateral caudate atrophy, more pronounced on the right
- severe bilateral accumbens atrophy, more pronounced on the right
- severe bilateral amygdala atrophy, more pronounced on the right
- moderate right atrophy of the hippocampus
- no degenerative or atrophic changes noted in the thalamus
- severe bilateral putamen atrophy, more pronounced on the right
For the cerebral cortex:
- severe bilateral insular cortex atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (severe), central operculum (severe), frontal operculum (moderate) and parietal operculum (between moderate and severe)
- no signs of atrophy detected in the occipital lobe
- severe bilateral limbic cortex atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: entorhinal area (between moderate and severe), anterior cingulate gyrus (severe) and middle cingulate gyrus (between moderate and severe)
- moderate atrophy of the temporal lobe, more pronounced on the right, with focal volume loss observed in the following subregions: middle temporal gyrus (between moderate and severe) and inf. temporal gyrus (mild)
- severe bilateral frontal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: gyrus rectus (moderate), triangular inf. frontal gyrus (moderate), middle frontal gyrus (moderate), anterior orbital gyrus (between mild and moderate), medial orbital gyrus (severe), posterior orbital gyrus (moderate), sup. frontal gyrus (between moderate and severe), sup. frontal gyrus medial segment (moderate) and precentral gyrus (between mild and moderate)
- mild atrophy of the parietal lobe, more pronounced on the right, with focal volume loss observed in the following subregions: postcentral gyrus (moderate) and supramarginal gyrus (between mild and moderate)
For the ventricles:
- severe enlargement of the external csf
- severe bilateral inf. lateral ventricle enlargement, more pronounced on the right
- between moderate and severe bilateral lateral ventricle enlargement
- severe enlargement of the 3rd ventricle
- 4th ventricle remains within normal size parameters, with no enlargement detected | BV |
NIFD_1_S_0132_MR_T1_mprage_S3_DIS3D_br_raw_20130722152424568_4_S196033_I381938 | On a T1-weighted brain MRI of a 65-year-old male subject, we observed:
For the ventricles:
- between moderate and severe enlargement of the 4th ventricle
- between moderate and severe enlargement of the external csf
- between moderate and severe bilateral lateral ventricle enlargement, more pronounced on the left
- severe bilateral inf. lateral ventricle enlargement, more pronounced on the left
- severe enlargement of the 3rd ventricle
For the cerebral cortex:
- the parietal lobe shows no structural abnormalities indicative of atrophy
- occipital lobe presents with a healthy appearance, free from atrophy
- severe bilateral temporal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: planum temporale (severe), inf. temporal gyrus (severe), middle temporal gyrus (severe), transverse temporal gyrus (between normal and mild) and temporal pole (moderate)
- severe bilateral insular cortex atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (moderate) and parietal operculum (between moderate and severe)
- severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (severe) and middle cingulate gyrus (severe)
- severe bilateral frontal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: frontal pole (severe), gyrus rectus (severe), medial frontal cortex (between moderate and severe), middle frontal gyrus (between mild and moderate), anterior orbital gyrus (between mild and moderate), lateral orbital gyrus (between mild and moderate), medial orbital gyrus (severe), posterior orbital gyrus (mild), precentral gyrus (between normal and mild), subcallosal area (between moderate and severe) and sup. frontal gyrus medial segment (severe)
For the subcortical structures:
- no signs of atrophy detected in the hippocampus
- no observable atrophic alterations in the basal forebrain
- severe bilateral caudate atrophy, more pronounced on the left
- ventral dc presents with a healthy appearance, free from atrophy
- severe bilateral pallidum atrophy, more pronounced on the left
- severe bilateral accumbens atrophy
- between mild and moderate left atrophy of the thalamus
- severe bilateral amygdala atrophy, more pronounced on the left
- severe bilateral putamen atrophy, more pronounced on the left | BV |
NIFD_1_S_0064_MR_t1_mprage_S3_DIS3D_br_raw_20111019180821812_6_S125843_I261660 | On a T1-weighted brain MRI of a 66-year-old female subject, we observed:
For the ventricles:
- 4th ventricle remains within normal size parameters, with no enlargement detected
- mild enlargement of the inf. lateral ventricle, more pronounced on the left
- between moderate and severe enlargement of the 3rd ventricle
- the external csf shows no structural abnormalities indicative of enlargement
- moderate bilateral lateral ventricle enlargement
For the cerebral cortex:
- atrophies of temporal lobe on planum temporale (mild) and temporal pole (between normal and mild)
- between normal and mild atrophy of the insular cortex
- no evidence of atrophy or degeneration in the parietal lobe
- between normal and mild atrophy of the frontal lobe, more pronounced on the right, with focal volume loss observed in the following subregions: sup. frontal gyrus (between moderate and severe), sup. frontal gyrus medial segment (between moderate and severe) and precentral gyrus (mild)
- focal atrophy of limbic cortex on middle cingulate gyrus (between normal and mild)
- occipital lobe maintains its normal morphology without atrophic features
For the subcortical structures:
- mild right atrophy of the caudate
- no pathological changes consistent with atrophy detected in the thalamus
- hippocampus maintains its normal morphology without atrophic features
- moderate bilateral putamen atrophy
- mild right atrophy of the pallidum
- no pathological changes consistent with atrophy detected in the amygdala
- the ventral dc shows no structural abnormalities indicative of atrophy
- between normal and mild atrophy of the accumbens, more pronounced on the right
- between normal and mild left atrophy of the basal forebrain | BV |
NIFD_1_S_0204_MR_T1_mprage_S3_DIS3D_br_raw_20140901105232469_41_S229550_I441930 | On a T1-weighted brain MRI of a 74-year-old female subject, we observed:
For the ventricles:
- severe bilateral inf. lateral ventricle enlargement
- 3rd ventricle remains within normal size parameters, with no enlargement detected
- between moderate and severe enlargement of the external csf
- lateral ventricle maintains its normal volume without signs of enlargement
- 4th ventricle maintains its normal volume without signs of enlargement
For the subcortical structures:
- between moderate and severe bilateral caudate atrophy
- between mild and moderate bilateral hippocampus atrophy
- mild bilateral pallidum atrophy
- between mild and moderate bilateral accumbens atrophy
- severe bilateral amygdala atrophy, more pronounced on the right
- basal forebrain remains normal, with no signs of tissue loss
- between normal and mild atrophy of the thalamus, more pronounced on the left
- between normal and mild right atrophy of the ventral dc
- mild bilateral putamen atrophy
For the cerebral cortex:
- between moderate and severe atrophy of the limbic cortex, more pronounced on the left, with focal volume loss observed in the following subregions: anterior cingulate gyrus (between moderate and severe) and parahippocampal gyrus (between normal and mild)
- between normal and mild atrophy of the parietal lobe, with focal volume loss observed in the following subregions: angular gyrus (between normal and mild)
- focal atrophy of temporal lobe on planum polare (mild)
- focal atrophy of occipital lobe on calcarine cortex (mild)
- severe bilateral frontal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: frontal pole (between normal and mild), triangular inf. frontal gyrus (between normal and mild), medial frontal cortex (between normal and mild), middle frontal gyrus (mild), lateral orbital gyrus (between mild and moderate), precentral gyrus (moderate) and sup. frontal gyrus (between normal and mild)
- focal atrophy of insular cortex on frontal operculum (mild) | BV |
NIFD_1_S_0011_MR_t1_mprage_S3_DIS3D_br_raw_20110203102701100_95_S98797_I215662 | On a T1-weighted brain MRI of a 60-year-old male subject, we observed:
For the ventricles:
- no signs of enlargement detected in the lateral ventricle
- 4th ventricle maintains its normal volume without signs of enlargement
- mild enlargement of the inf. lateral ventricle, more pronounced on the right
- severe enlargement of the 3rd ventricle
- moderate enlargement of the external csf
For the cerebral cortex:
- occipital lobe appears structurally intact with no atrophic changes
- severe bilateral frontal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: gyrus rectus (between moderate and severe), medial frontal cortex (between normal and mild), lateral orbital gyrus (between normal and mild), medial orbital gyrus (moderate), posterior orbital gyrus (between mild and moderate), precentral gyrus medial segment (between normal and mild), sup. frontal gyrus medial segment (between mild and moderate) and supplementary motor cortex (between normal and mild)
- focal atrophy of parietal lobe on postcentral gyrus (between mild and moderate)
- focal atrophy of temporal lobe on temporal pole (between normal and mild)
- severe bilateral insular cortex atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (between moderate and severe), central operculum (moderate) and frontal operculum (between normal and mild)
- moderate atrophy of the limbic cortex, with focal volume loss observed in the following subregions: anterior cingulate gyrus (between moderate and severe)
For the subcortical structures:
- severe bilateral caudate atrophy, more pronounced on the right
- severe atrophy of the amygdala, more pronounced on the right
- no degenerative or atrophic changes noted in the ventral dc
- the basal forebrain shows no structural abnormalities indicative of atrophy
- no signs of atrophy detected in the pallidum
- between normal and mild atrophy of the hippocampus, more pronounced on the right
- moderate bilateral accumbens atrophy, more pronounced on the right
- moderate bilateral putamen atrophy, more pronounced on the right
- no pathological changes consistent with atrophy detected in the thalamus | BV |
NIFD_1_S_0356_MR_t1_mprage__br_raw_20170628174605905_151_S577026_I866521 | On a T1-weighted brain MRI of a 61-year-old female subject, we observed:
For the cerebral cortex:
- between moderate and severe bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe) and frontal operculum (severe)
- severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (severe) and posterior cingulate gyrus (between normal and mild)
- severe bilateral frontal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: gyrus rectus (severe), opercular inf. frontal gyrus (between moderate and severe), orbital inf. frontal gyrus (between moderate and severe), triangular inf. frontal gyrus (between mild and moderate), medial frontal cortex (severe), middle frontal gyrus (severe), anterior orbital gyrus (between mild and moderate), lateral orbital gyrus (severe), medial orbital gyrus (between moderate and severe), posterior orbital gyrus (between mild and moderate), sup. frontal gyrus (severe) and sup. frontal gyrus medial segment (severe)
- occipital lobe maintains its normal morphology without atrophic features
- severe atrophy of the temporal lobe, more pronounced on the right, with focal volume loss observed in the following subregions: fusiform gyrus (moderate), sup. temporal gyrus (between mild and moderate) and temporal pole (severe)
- parietal lobe appears structurally intact with no atrophic changes
For the subcortical structures:
- no evidence of atrophy or degeneration in the pallidum
- mild atrophy of the hippocampus, more pronounced on the right
- no pathological changes consistent with atrophy detected in the basal forebrain
- thalamus remains normal, with no signs of tissue loss
- severe bilateral amygdala atrophy, more pronounced on the right
- between normal and mild right atrophy of the putamen
- between normal and mild atrophy of the caudate, more pronounced on the right
- no signs of atrophy detected in the ventral dc
- severe bilateral accumbens atrophy, more pronounced on the right
For the ventricles:
- lateral ventricle appears structurally intact, with no evidence of enlargement
- 3rd ventricle is free from enlargement or excessive growth
- between mild and moderate enlargement of the inf. lateral ventricle, more pronounced on the right
- severe enlargement of the external csf
- 4th ventricle appears structurally intact, with no evidence of enlargement | BV |
NIFD_2_S_0006_MR_MT1__GradWarp__N3m_Br_20111229185330471_S133333_I274726 | On a T1-weighted brain MRI of a 64-year-old male subject, we observed:
For the subcortical structures:
- no observable atrophic alterations in the basal forebrain
- between moderate and severe left atrophy of the putamen
- severe bilateral hippocampus atrophy, more pronounced on the left
- no pathological changes consistent with atrophy detected in the accumbens
- between normal and mild left atrophy of the pallidum
- severe bilateral amygdala atrophy, more pronounced on the left
- moderate left atrophy of the thalamus
- between mild and moderate bilateral ventral dc atrophy, more pronounced on the left
- between moderate and severe bilateral caudate atrophy, more pronounced on the left
For the ventricles:
- severe enlargement of the inf. lateral ventricle, more pronounced on the left
- no observable enlargement or abnormal growth in the 3rd ventricle
- severe enlargement of the external csf
- 4th ventricle appears structurally intact, with no evidence of enlargement
- mild enlargement of the lateral ventricle
For the cerebral cortex:
- insular cortex appears structurally intact with no atrophic changes
- focal atrophy of frontal lobe on gyrus rectus (moderate)
- mild atrophy of the parietal lobe, more pronounced on the left, with focal volume loss observed in the following subregions: angular gyrus (between normal and mild)
- focal atrophy of occipital lobe on occipital fusiform gyrus (moderate)
- severe atrophy of the temporal lobe, more pronounced on the left, with focal volume loss observed in the following subregions: inf. temporal gyrus (severe), temporal pole (moderate), planum temporale (mild), middle temporal gyrus (between moderate and severe) and sup. temporal gyrus (moderate)
- between moderate and severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (moderate), anterior cingulate gyrus (between normal and mild), middle cingulate gyrus (between normal and mild) and parahippocampal gyrus (between normal and mild) | BV |
NIFD_2_S_0031_MR_MT1__GradWarp__N3m_Br_20130514103437416_S188985_I372252 | On a T1-weighted brain MRI of a 66-year-old female subject, we observed:
For the subcortical structures:
- ventral dc maintains its normal morphology without atrophic features
- basal forebrain appears structurally intact with no atrophic changes
- severe bilateral caudate atrophy, more pronounced on the right
- between mild and moderate right atrophy of the thalamus
- between mild and moderate atrophy of the pallidum, more pronounced on the right
- moderate right atrophy of the hippocampus
- severe bilateral amygdala atrophy, more pronounced on the right
- severe bilateral accumbens atrophy, more pronounced on the right
- severe bilateral putamen atrophy, more pronounced on the right
For the cerebral cortex:
- severe atrophy of the frontal lobe, more pronounced on the right, with focal volume loss observed in the following subregions: gyrus rectus (between moderate and severe), opercular inf. frontal gyrus (severe), medial frontal cortex (mild), anterior orbital gyrus (between moderate and severe), lateral orbital gyrus (between moderate and severe), medial orbital gyrus (severe), posterior orbital gyrus (severe), sup. frontal gyrus (between normal and mild), sup. frontal gyrus medial segment (severe), triangular inf. frontal gyrus (mild) and orbital inf. frontal gyrus (mild)
- severe atrophy of the limbic cortex, more pronounced on the right, with focal volume loss observed in the following subregions: anterior cingulate gyrus (severe)
- between moderate and severe atrophy of the insular cortex, more pronounced on the right, with focal volume loss observed in the following subregions: anterior insula (severe) and frontal operculum (moderate)
- parietal lobe appears structurally intact with no atrophic changes
- occipital lobe appears structurally intact with no atrophic changes
- atrophies of temporal lobe on middle temporal gyrus (between normal and mild) and temporal pole (between moderate and severe)
For the ventricles:
- mild bilateral lateral ventricle enlargement
- between moderate and severe enlargement of the inf. lateral ventricle, more pronounced on the right
- no abnormal enlargement observed in the 4th ventricle
- moderate enlargement of the external csf
- between moderate and severe enlargement of the 3rd ventricle | BV |
NIFD_1_S_0095_MR_T1_mprage_S3_DIS3D_br_raw_20120819163606804_114_S161475_I324728 | On a T1-weighted brain MRI of a 73-year-old female subject, we observed:
For the ventricles:
- severe bilateral lateral ventricle enlargement
- severe enlargement of the 3rd ventricle
- severe bilateral inf. lateral ventricle enlargement
- no observable enlargement or abnormal growth in the 4th ventricle
- external csf maintains its normal volume without signs of enlargement
For the cerebral cortex:
- severe bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (moderate), gyrus rectus (moderate), opercular inf. frontal gyrus (between normal and mild), orbital inf. frontal gyrus (moderate), triangular inf. frontal gyrus (between normal and mild), medial frontal cortex (moderate), middle frontal gyrus (severe), anterior orbital gyrus (between normal and mild), medial orbital gyrus (moderate), sup. frontal gyrus (between normal and mild) and sup. frontal gyrus medial segment (between mild and moderate)
- severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (between mild and moderate), anterior cingulate gyrus (between moderate and severe) and parahippocampal gyrus (between mild and moderate)
- atrophies of occipital lobe on calcarine cortex (between normal and mild) and occipital pole (between mild and moderate)
- mild atrophy of the insular cortex, with focal volume loss observed in the following subregions: anterior insula (between mild and moderate)
- no degenerative or atrophic changes noted in the parietal lobe
- no pathological changes consistent with atrophy detected in the temporal lobe
For the subcortical structures:
- no observable atrophic alterations in the ventral dc
- moderate bilateral hippocampus atrophy, more pronounced on the right
- severe bilateral caudate atrophy
- moderate bilateral pallidum atrophy, more pronounced on the left
- between moderate and severe bilateral thalamus atrophy
- severe bilateral accumbens atrophy, more pronounced on the left
- the basal forebrain shows no structural abnormalities indicative of atrophy
- severe bilateral putamen atrophy
- severe bilateral amygdala atrophy, more pronounced on the left | BV |
NIFD_1_S_0085_MR_T1_mprage_S3_DIS3D_br_raw_20120307000133150_31_S143023_I288641 | On a T1-weighted brain MRI of a 47-year-old female subject, we observed:
For the cerebral cortex:
- insular cortex maintains its normal morphology without atrophic features
- focal atrophy of parietal lobe on precuneus (between normal and mild)
- focal atrophy of temporal lobe on temporal pole (between moderate and severe)
- limbic cortex appears structurally intact with no atrophic changes
- mild atrophy of the frontal lobe, more pronounced on the left, with focal volume loss observed in the following subregions: middle frontal gyrus (between moderate and severe), lateral orbital gyrus (between normal and mild) and sup. frontal gyrus medial segment (between normal and mild)
- occipital lobe appears structurally intact with no atrophic changes
For the ventricles:
- moderate enlargement of the 3rd ventricle
- severe enlargement of the external csf
- 4th ventricle is free from enlargement or excessive growth
- the lateral ventricle shows no structural abnormalities indicative of enlargement
- inf. lateral ventricle is free from enlargement or excessive growth
For the subcortical structures:
- no signs of atrophy detected in the basal forebrain
- between normal and mild atrophy of the ventral dc, more pronounced on the left
- between moderate and severe atrophy of the thalamus, more pronounced on the left
- between normal and mild left atrophy of the putamen
- between moderate and severe bilateral hippocampus atrophy
- between normal and mild left atrophy of the amygdala
- accumbens remains normal, with no signs of tissue loss
- between normal and mild atrophy of the caudate, more pronounced on the left
- mild atrophy of the pallidum, more pronounced on the left | BV |
NIFD_2_S_0032_MR_MT1__GradWarp__N3m_Br_20130613083444087_S191547_I376358 | On a T1-weighted brain MRI of a 58-year-old male subject, we observed:
For the cerebral cortex:
- no signs of atrophy detected in the parietal lobe
- no degenerative or atrophic changes noted in the limbic cortex
- focal atrophy of temporal lobe on inf. temporal gyrus (mild)
- frontal lobe remains normal, with no signs of tissue loss
- focal atrophy of insular cortex on parietal operculum (between normal and mild)
- focal atrophy of occipital lobe on sup. occipital gyrus (between mild and moderate)
For the subcortical structures:
- caudate remains normal, with no signs of tissue loss
- no pathological changes consistent with atrophy detected in the ventral dc
- no signs of atrophy detected in the pallidum
- mild atrophy of the amygdala
- no degenerative or atrophic changes noted in the putamen
- accumbens appears structurally intact with no atrophic changes
- basal forebrain maintains its normal morphology without atrophic features
- no signs of atrophy detected in the thalamus
- between moderate and severe bilateral hippocampus atrophy
For the ventricles:
- no observable enlargement or abnormal growth in the 4th ventricle
- inf. lateral ventricle remains within normal size parameters, with no enlargement detected
- lateral ventricle appears structurally intact, with no evidence of enlargement
- moderate enlargement of the external csf
- no abnormal enlargement observed in the 3rd ventricle | BV |
NIFD_1_S_0102_MR_T1_mprage_S3_DIS3D_br_raw_20170816161439198_36_S596667_I889712 | On a T1-weighted brain MRI of a 71-year-old male subject, we observed:
For the cerebral cortex:
- mild atrophy of the limbic cortex, more pronounced on the left, with focal volume loss observed in the following subregions: anterior cingulate gyrus (moderate) and middle cingulate gyrus (mild)
- severe bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (moderate), gyrus rectus (between mild and moderate), middle frontal gyrus (severe), precentral gyrus (severe), sup. frontal gyrus (between mild and moderate) and supplementary motor cortex (moderate)
- occipital lobe presents with a healthy appearance, free from atrophy
- atrophies of insular cortex on anterior insula (moderate) and frontal operculum (mild)
- focal atrophy of parietal lobe on angular gyrus (between normal and mild)
- temporal lobe appears structurally intact with no atrophic changes
For the subcortical structures:
- mild atrophy of the basal forebrain, more pronounced on the left
- severe bilateral ventral dc atrophy, more pronounced on the left
- between normal and mild left atrophy of the accumbens
- severe bilateral putamen atrophy, more pronounced on the left
- severe bilateral thalamus atrophy, more pronounced on the left
- between normal and mild atrophy of the amygdala
- severe bilateral pallidum atrophy, more pronounced on the left
- between mild and moderate bilateral hippocampus atrophy
- severe bilateral caudate atrophy, more pronounced on the left
For the ventricles:
- severe enlargement of the external csf
- inf. lateral ventricle remains within normal size parameters, with no enlargement detected
- between mild and moderate left enlargement of the lateral ventricle
- between mild and moderate enlargement of the 3rd ventricle
- 4th ventricle appears structurally intact, with no evidence of enlargement | BV |
NIFD_1_S_0130_MR_T1_mprage_S3_DIS3D_br_raw_20130719163246403_84_S195891_I381770 | On a T1-weighted brain MRI of a 58-year-old male subject, we observed:
For the ventricles:
- between moderate and severe enlargement of the lateral ventricle, more pronounced on the left
- between moderate and severe enlargement of the 3rd ventricle
- 4th ventricle maintains its normal volume without signs of enlargement
- between mild and moderate enlargement of the external csf
- severe bilateral inf. lateral ventricle enlargement, more pronounced on the left
For the subcortical structures:
- between normal and mild atrophy of the ventral dc, more pronounced on the left
- basal forebrain maintains its normal morphology without atrophic features
- moderate atrophy of the thalamus, more pronounced on the left
- severe bilateral putamen atrophy, more pronounced on the left
- severe bilateral caudate atrophy, more pronounced on the left
- moderate bilateral amygdala atrophy
- between normal and mild left atrophy of the accumbens
- between mild and moderate bilateral hippocampus atrophy
- between moderate and severe bilateral pallidum atrophy, more pronounced on the left
For the cerebral cortex:
- mild atrophy of the insular cortex, more pronounced on the left, with focal volume loss observed in the following subregions: anterior insula (severe)
- focal atrophy of frontal lobe on middle frontal gyrus (between normal and mild)
- between moderate and severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (moderate)
- parietal lobe appears structurally intact with no atrophic changes
- focal atrophy of occipital lobe on occipital fusiform gyrus (mild)
- focal atrophy of temporal lobe on planum temporale (between normal and mild) | BV |
NIFD_1_S_0332_MR_t1_mprage_short__br_raw_20170628200022329_22_S577253_I866807 | On a T1-weighted brain MRI of a 55-year-old male subject, we observed:
For the ventricles:
- severe bilateral inf. lateral ventricle enlargement
- between mild and moderate enlargement of the external csf
- mild enlargement of the lateral ventricle
- severe enlargement of the 4th ventricle
- moderate enlargement of the 3rd ventricle
For the cerebral cortex:
- focal atrophy of occipital lobe on inf. occipital gyrus (mild)
- moderate bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (between mild and moderate) and anterior cingulate gyrus (between mild and moderate)
- between mild and moderate bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: postcentral gyrus medial segment (moderate) and sup. parietal lobule (between mild and moderate)
- insular cortex appears structurally intact with no atrophic changes
- atrophies of temporal lobe on planum polare (between mild and moderate) and middle temporal gyrus (between normal and mild)
- atrophies of frontal lobe on middle frontal gyrus (between normal and mild) and sup. frontal gyrus medial segment (between normal and mild)
For the subcortical structures:
- no evidence of atrophy or degeneration in the amygdala
- severe bilateral accumbens atrophy, more pronounced on the right
- ventral dc presents with a healthy appearance, free from atrophy
- thalamus remains normal, with no signs of tissue loss
- moderate bilateral caudate atrophy
- hippocampus maintains its normal morphology without atrophic features
- no observable atrophic alterations in the basal forebrain
- moderate bilateral putamen atrophy
- moderate bilateral pallidum atrophy | BV |
NIFD_2_S_0021_MR_MT1__GradWarp__N3m_Br_20130114173911629_S160243_I355049 | On a T1-weighted brain MRI of a 60-year-old male subject, we observed:
For the ventricles:
- external csf maintains its normal volume without signs of enlargement
- inf. lateral ventricle appears structurally intact, with no evidence of enlargement
- no signs of enlargement detected in the lateral ventricle
- no observable enlargement or abnormal growth in the 3rd ventricle
- between normal and mild enlargement of the 4th ventricle
For the cerebral cortex:
- the temporal lobe shows no structural abnormalities indicative of atrophy
- focal atrophy of insular cortex on parietal operculum (between normal and mild)
- the parietal lobe shows no structural abnormalities indicative of atrophy
- focal atrophy of frontal lobe on opercular inf. frontal gyrus (moderate)
- occipital lobe appears structurally intact with no atrophic changes
- atrophies of limbic cortex on middle cingulate gyrus (mild) and posterior cingulate gyrus (between normal and mild)
For the subcortical structures:
- putamen appears structurally intact with no atrophic changes
- amygdala maintains its normal morphology without atrophic features
- no degenerative or atrophic changes noted in the basal forebrain
- the accumbens shows no structural abnormalities indicative of atrophy
- no signs of atrophy detected in the pallidum
- no degenerative or atrophic changes noted in the caudate
- the ventral dc shows no structural abnormalities indicative of atrophy
- no observable atrophic alterations in the hippocampus
- no degenerative or atrophic changes noted in the thalamus | BV |
NIFD_2_S_0021_MR_MT1__GradWarp__N3m_Br_20130114173911629_S160243_I355049 | On a T1-weighted brain MRI of a 60-year-old male subject, we observed:
For the ventricles:
- no signs of enlargement detected in the 3rd ventricle
- no enlargement observed in the inf. lateral ventricle
- between normal and mild enlargement of the 4th ventricle
- no enlargement observed in the lateral ventricle
- no abnormal enlargement observed in the external csf
For the cerebral cortex:
- atrophies of limbic cortex on middle cingulate gyrus (mild) and posterior cingulate gyrus (between normal and mild)
- temporal lobe presents with a healthy appearance, free from atrophy
- the occipital lobe shows no structural abnormalities indicative of atrophy
- focal atrophy of frontal lobe on opercular inf. frontal gyrus (moderate)
- focal atrophy of insular cortex on parietal operculum (between normal and mild)
- the parietal lobe shows no structural abnormalities indicative of atrophy
For the subcortical structures:
- amygdala remains normal, with no signs of tissue loss
- pallidum remains normal, with no signs of tissue loss
- the accumbens shows no structural abnormalities indicative of atrophy
- no degenerative or atrophic changes noted in the thalamus
- putamen remains normal, with no signs of tissue loss
- no pathological changes consistent with atrophy detected in the ventral dc
- the basal forebrain shows no structural abnormalities indicative of atrophy
- no pathological changes consistent with atrophy detected in the caudate
- no signs of atrophy detected in the hippocampus | BV |
NIFD_2_S_0030_MR_MT1__GradWarp__N3m_Br_20130111113347184_S179870_I354749 | On a T1-weighted brain MRI of a 65-year-old male subject, we observed:
For the cerebral cortex:
- no signs of atrophy detected in the parietal lobe
- between moderate and severe bilateral temporal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: fusiform gyrus (between normal and mild), middle temporal gyrus (mild) and sup. temporal gyrus (between mild and moderate)
- focal atrophy of limbic cortex on anterior cingulate gyrus (severe)
- severe bilateral frontal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: frontal pole (between moderate and severe), gyrus rectus (mild), opercular inf. frontal gyrus (between mild and moderate), triangular inf. frontal gyrus (mild), medial frontal cortex (between mild and moderate), middle frontal gyrus (severe), lateral orbital gyrus (moderate), medial orbital gyrus (severe), sup. frontal gyrus (severe) and supplementary motor cortex (moderate)
- between moderate and severe bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (moderate) and frontal operculum (moderate)
- no signs of atrophy detected in the occipital lobe
For the subcortical structures:
- between normal and mild atrophy of the hippocampus, more pronounced on the left
- no evidence of atrophy or degeneration in the basal forebrain
- between moderate and severe atrophy of the amygdala, more pronounced on the left
- severe bilateral caudate atrophy, more pronounced on the left
- between mild and moderate left atrophy of the thalamus
- no pathological changes consistent with atrophy detected in the ventral dc
- mild left atrophy of the pallidum
- severe bilateral putamen atrophy, more pronounced on the left
- severe bilateral accumbens atrophy, more pronounced on the left
For the ventricles:
- no signs of enlargement detected in the 4th ventricle
- between normal and mild enlargement of the 3rd ventricle
- moderate enlargement of the inf. lateral ventricle, more pronounced on the left
- severe enlargement of the external csf
- the lateral ventricle shows no structural abnormalities indicative of enlargement | BV |
NIFD_1_S_0356_MR_t1_mprage__br_raw_20170628174605905_151_S577026_I866521 | On a T1-weighted brain MRI of a 61-year-old female subject, we observed:
For the cerebral cortex:
- severe bilateral frontal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: gyrus rectus (severe), opercular inf. frontal gyrus (between moderate and severe), orbital inf. frontal gyrus (between moderate and severe), triangular inf. frontal gyrus (between mild and moderate), medial frontal cortex (severe), middle frontal gyrus (severe), anterior orbital gyrus (between mild and moderate), lateral orbital gyrus (severe), medial orbital gyrus (between moderate and severe), posterior orbital gyrus (between mild and moderate), sup. frontal gyrus (severe) and sup. frontal gyrus medial segment (severe)
- between moderate and severe bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe) and frontal operculum (severe)
- occipital lobe maintains its normal morphology without atrophic features
- severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (severe) and posterior cingulate gyrus (between normal and mild)
- severe atrophy of the temporal lobe, more pronounced on the right, with focal volume loss observed in the following subregions: fusiform gyrus (moderate), sup. temporal gyrus (between mild and moderate) and temporal pole (severe)
- no degenerative or atrophic changes noted in the parietal lobe
For the ventricles:
- between mild and moderate enlargement of the inf. lateral ventricle, more pronounced on the right
- the lateral ventricle shows no structural abnormalities indicative of enlargement
- severe enlargement of the external csf
- 4th ventricle appears structurally intact, with no evidence of enlargement
- 3rd ventricle appears structurally intact, with no evidence of enlargement
For the subcortical structures:
- severe bilateral amygdala atrophy, more pronounced on the right
- pallidum appears structurally intact with no atrophic changes
- severe bilateral accumbens atrophy, more pronounced on the right
- between normal and mild right atrophy of the putamen
- between normal and mild atrophy of the caudate, more pronounced on the right
- no degenerative or atrophic changes noted in the basal forebrain
- mild atrophy of the hippocampus, more pronounced on the right
- ventral dc remains normal, with no signs of tissue loss
- thalamus presents with a healthy appearance, free from atrophy | BV |
NIFD_2_S_0030_MR_MT1__GradWarp__N3m_Br_20130111113347184_S179870_I354749 | On a T1-weighted brain MRI of a 65-year-old male subject, we observed:
For the subcortical structures:
- severe bilateral putamen atrophy, more pronounced on the left
- severe bilateral accumbens atrophy, more pronounced on the left
- between moderate and severe atrophy of the amygdala, more pronounced on the left
- between normal and mild atrophy of the hippocampus, more pronounced on the left
- ventral dc remains normal, with no signs of tissue loss
- no degenerative or atrophic changes noted in the basal forebrain
- between mild and moderate left atrophy of the thalamus
- mild left atrophy of the pallidum
- severe bilateral caudate atrophy, more pronounced on the left
For the cerebral cortex:
- between moderate and severe bilateral temporal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: fusiform gyrus (between normal and mild), middle temporal gyrus (mild) and sup. temporal gyrus (between mild and moderate)
- severe bilateral frontal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: frontal pole (between moderate and severe), gyrus rectus (mild), opercular inf. frontal gyrus (between mild and moderate), triangular inf. frontal gyrus (mild), medial frontal cortex (between mild and moderate), middle frontal gyrus (severe), lateral orbital gyrus (moderate), medial orbital gyrus (severe), sup. frontal gyrus (severe) and supplementary motor cortex (moderate)
- focal atrophy of limbic cortex on anterior cingulate gyrus (severe)
- no evidence of atrophy or degeneration in the parietal lobe
- between moderate and severe bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (moderate) and frontal operculum (moderate)
- the occipital lobe shows no structural abnormalities indicative of atrophy
For the ventricles:
- 4th ventricle appears structurally intact, with no evidence of enlargement
- no observable enlargement or abnormal growth in the lateral ventricle
- moderate enlargement of the inf. lateral ventricle, more pronounced on the left
- between normal and mild enlargement of the 3rd ventricle
- severe enlargement of the external csf | BV |
NIFD_1_S_0209_MR_T1_mprage_S3_DIS3D_br_raw_20140901123615201_24_S229648_I442043 | On a T1-weighted brain MRI of a 58-year-old female subject, we observed:
For the ventricles:
- 4th ventricle appears structurally intact, with no evidence of enlargement
- severe enlargement of the 3rd ventricle
- moderate bilateral inf. lateral ventricle enlargement
- between mild and moderate enlargement of the external csf
- between moderate and severe bilateral lateral ventricle enlargement
For the subcortical structures:
- between moderate and severe bilateral putamen atrophy, more pronounced on the right
- between mild and moderate bilateral accumbens atrophy
- severe bilateral caudate atrophy
- the basal forebrain shows no structural abnormalities indicative of atrophy
- ventral dc appears structurally intact with no atrophic changes
- no evidence of atrophy or degeneration in the hippocampus
- between mild and moderate bilateral amygdala atrophy
- between normal and mild right atrophy of the pallidum
- mild bilateral thalamus atrophy
For the cerebral cortex:
- no pathological changes consistent with atrophy detected in the occipital lobe
- focal atrophy of temporal lobe on temporal pole (between mild and moderate)
- severe bilateral frontal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: frontal pole (mild), opercular inf. frontal gyrus (severe), orbital inf. frontal gyrus (between normal and mild), triangular inf. frontal gyrus (between moderate and severe), medial frontal cortex (mild), middle frontal gyrus (moderate), posterior orbital gyrus (between mild and moderate), sup. frontal gyrus (between moderate and severe) and sup. frontal gyrus medial segment (between normal and mild)
- moderate bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (moderate) and parahippocampal gyrus (between normal and mild)
- parietal lobe remains normal, with no signs of tissue loss
- atrophies of insular cortex on anterior insula (mild) and frontal operculum (between mild and moderate) | BV |
NIFD_1_S_0119_MR_t1_mprage_S3_DIS3D_br_raw_20170814185756776_15_S594508_I887000 | On a T1-weighted brain MRI of a 70-year-old female subject, we observed:
For the cerebral cortex:
- mild atrophy of the temporal lobe, with focal volume loss observed in the following subregions: fusiform gyrus (between normal and mild)
- no signs of atrophy detected in the limbic cortex
- the occipital lobe shows no structural abnormalities indicative of atrophy
- focal atrophy of insular cortex on anterior insula (between mild and moderate)
- atrophies of parietal lobe on postcentral gyrus (moderate) and precuneus (between normal and mild)
- mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: middle frontal gyrus (mild), precentral gyrus (between mild and moderate) and sup. frontal gyrus medial segment (mild)
For the subcortical structures:
- accumbens remains normal, with no signs of tissue loss
- moderate atrophy of the basal forebrain, more pronounced on the left
- mild bilateral amygdala atrophy
- between mild and moderate bilateral caudate atrophy
- between mild and moderate atrophy of the hippocampus
- mild bilateral putamen atrophy
- moderate bilateral ventral dc atrophy
- moderate bilateral thalamus atrophy
- between moderate and severe bilateral pallidum atrophy
For the ventricles:
- no signs of enlargement detected in the 3rd ventricle
- 4th ventricle maintains its normal volume without signs of enlargement
- no pathological changes consistent with enlargement noted in the lateral ventricle
- between mild and moderate enlargement of the external csf
- no observable enlargement or abnormal growth in the inf. lateral ventricle | BV |
NIFD_1_S_0029_MR_t1_mprage_S4_DIS3D_br_raw_20110209101901199_30_S99286_I216392 | On a T1-weighted brain MRI of a 58-year-old female subject, we observed:
For the subcortical structures:
- severe bilateral hippocampus atrophy, more pronounced on the right
- moderate bilateral thalamus atrophy
- severe bilateral accumbens atrophy, more pronounced on the left
- the basal forebrain shows no structural abnormalities indicative of atrophy
- severe bilateral putamen atrophy, more pronounced on the left
- moderate bilateral ventral dc atrophy
- severe bilateral caudate atrophy, more pronounced on the left
- severe bilateral pallidum atrophy, more pronounced on the left
- severe bilateral amygdala atrophy, more pronounced on the right
For the cerebral cortex:
- focal atrophy of temporal lobe on planum polare (between normal and mild)
- no evidence of atrophy or degeneration in the parietal lobe
- moderate bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (severe)
- occipital lobe presents with a healthy appearance, free from atrophy
- mild atrophy of the frontal lobe, with focal volume loss observed in the following subregions: gyrus rectus (mild), medial frontal cortex (between normal and mild) and sup. frontal gyrus (moderate)
- moderate bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe) and frontal operculum (moderate)
For the ventricles:
- moderate enlargement of the 3rd ventricle
- severe bilateral inf. lateral ventricle enlargement
- moderate bilateral lateral ventricle enlargement
- no abnormal enlargement observed in the 4th ventricle
- external csf remains within normal size parameters, with no enlargement detected | BV |
NIFD_2_S_0030_MR_MT1__GradWarp__N3m_Br_20130111113347184_S179870_I354749 | On a T1-weighted brain MRI of a 65-year-old male subject, we observed:
For the ventricles:
- moderate enlargement of the inf. lateral ventricle, more pronounced on the left
- 4th ventricle maintains its normal volume without signs of enlargement
- lateral ventricle remains within normal size parameters, with no enlargement detected
- severe enlargement of the external csf
- between normal and mild enlargement of the 3rd ventricle
For the subcortical structures:
- basal forebrain maintains its normal morphology without atrophic features
- severe bilateral caudate atrophy, more pronounced on the left
- severe bilateral putamen atrophy, more pronounced on the left
- between normal and mild atrophy of the hippocampus, more pronounced on the left
- between mild and moderate left atrophy of the thalamus
- mild left atrophy of the pallidum
- no degenerative or atrophic changes noted in the ventral dc
- between moderate and severe atrophy of the amygdala, more pronounced on the left
- severe bilateral accumbens atrophy, more pronounced on the left
For the cerebral cortex:
- occipital lobe presents with a healthy appearance, free from atrophy
- between moderate and severe bilateral temporal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: fusiform gyrus (between normal and mild), middle temporal gyrus (mild) and sup. temporal gyrus (between mild and moderate)
- parietal lobe presents with a healthy appearance, free from atrophy
- between moderate and severe bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (moderate) and frontal operculum (moderate)
- focal atrophy of limbic cortex on anterior cingulate gyrus (severe)
- severe bilateral frontal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: frontal pole (between moderate and severe), gyrus rectus (mild), opercular inf. frontal gyrus (between mild and moderate), triangular inf. frontal gyrus (mild), medial frontal cortex (between mild and moderate), middle frontal gyrus (severe), lateral orbital gyrus (moderate), medial orbital gyrus (severe), sup. frontal gyrus (severe) and supplementary motor cortex (moderate) | BV |
NIFD_1_S_0322_MR_t1_mprage__br_raw_20170628162001259_142_S576863_I866324 | On a T1-weighted brain MRI of a 45-year-old male subject, we observed:
For the cerebral cortex:
- the parietal lobe shows no structural abnormalities indicative of atrophy
- focal atrophy of limbic cortex on anterior cingulate gyrus (moderate)
- atrophies of occipital lobe on cuneus (mild) and occipital pole (between mild and moderate)
- focal atrophy of temporal lobe on transverse temporal gyrus (between normal and mild)
- severe bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (between moderate and severe), opercular inf. frontal gyrus (mild), middle frontal gyrus (between moderate and severe), anterior orbital gyrus (mild), precentral gyrus (between mild and moderate), sup. frontal gyrus (moderate) and sup. frontal gyrus medial segment (severe)
- mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: central operculum (between mild and moderate) and frontal operculum (mild)
For the subcortical structures:
- between mild and moderate bilateral pallidum atrophy
- between normal and mild left atrophy of the hippocampus
- between normal and mild left atrophy of the accumbens
- between moderate and severe bilateral caudate atrophy, more pronounced on the left
- no evidence of atrophy or degeneration in the ventral dc
- basal forebrain presents with a healthy appearance, free from atrophy
- moderate bilateral putamen atrophy, more pronounced on the left
- no pathological changes consistent with atrophy detected in the amygdala
- moderate bilateral thalamus atrophy
For the ventricles:
- between normal and mild enlargement of the 3rd ventricle
- severe bilateral inf. lateral ventricle enlargement, more pronounced on the left
- no observable enlargement or abnormal growth in the 4th ventricle
- mild enlargement of the external csf
- severe bilateral lateral ventricle enlargement | BV |
NIFD_2_S_0031_MR_MT1__GradWarp__N3m_Br_20130514103437416_S188985_I372252 | On a T1-weighted brain MRI of a 66-year-old female subject, we observed:
For the subcortical structures:
- severe bilateral accumbens atrophy, more pronounced on the right
- moderate right atrophy of the hippocampus
- between mild and moderate atrophy of the pallidum, more pronounced on the right
- no signs of atrophy detected in the ventral dc
- severe bilateral caudate atrophy, more pronounced on the right
- between mild and moderate right atrophy of the thalamus
- severe bilateral amygdala atrophy, more pronounced on the right
- severe bilateral putamen atrophy, more pronounced on the right
- no degenerative or atrophic changes noted in the basal forebrain
For the ventricles:
- moderate enlargement of the external csf
- between moderate and severe enlargement of the inf. lateral ventricle, more pronounced on the right
- 4th ventricle remains within normal size parameters, with no enlargement detected
- between moderate and severe enlargement of the 3rd ventricle
- mild bilateral lateral ventricle enlargement
For the cerebral cortex:
- between moderate and severe atrophy of the insular cortex, more pronounced on the right, with focal volume loss observed in the following subregions: anterior insula (severe) and frontal operculum (moderate)
- no observable atrophic alterations in the occipital lobe
- atrophies of temporal lobe on middle temporal gyrus (between normal and mild) and temporal pole (between moderate and severe)
- no evidence of atrophy or degeneration in the parietal lobe
- severe atrophy of the limbic cortex, more pronounced on the right, with focal volume loss observed in the following subregions: anterior cingulate gyrus (severe)
- severe atrophy of the frontal lobe, more pronounced on the right, with focal volume loss observed in the following subregions: gyrus rectus (between moderate and severe), opercular inf. frontal gyrus (severe), medial frontal cortex (mild), anterior orbital gyrus (between moderate and severe), lateral orbital gyrus (between moderate and severe), medial orbital gyrus (severe), posterior orbital gyrus (severe), sup. frontal gyrus (between normal and mild), sup. frontal gyrus medial segment (severe), triangular inf. frontal gyrus (mild) and orbital inf. frontal gyrus (mild) | BV |
NIFD_1_S_0029_MR_t1_mprage_S4_DIS3D_br_raw_20110209101901199_30_S99286_I216392 | On a T1-weighted brain MRI of a 58-year-old female subject, we observed:
For the subcortical structures:
- severe bilateral putamen atrophy, more pronounced on the left
- severe bilateral amygdala atrophy, more pronounced on the right
- moderate bilateral thalamus atrophy
- basal forebrain remains normal, with no signs of tissue loss
- severe bilateral caudate atrophy, more pronounced on the left
- moderate bilateral ventral dc atrophy
- severe bilateral hippocampus atrophy, more pronounced on the right
- severe bilateral accumbens atrophy, more pronounced on the left
- severe bilateral pallidum atrophy, more pronounced on the left
For the ventricles:
- moderate enlargement of the 3rd ventricle
- 4th ventricle maintains its normal volume without signs of enlargement
- moderate bilateral lateral ventricle enlargement
- no observable enlargement or abnormal growth in the external csf
- severe bilateral inf. lateral ventricle enlargement
For the cerebral cortex:
- moderate bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe) and frontal operculum (moderate)
- mild atrophy of the frontal lobe, with focal volume loss observed in the following subregions: gyrus rectus (mild), medial frontal cortex (between normal and mild) and sup. frontal gyrus (moderate)
- parietal lobe presents with a healthy appearance, free from atrophy
- moderate bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (severe)
- focal atrophy of temporal lobe on planum polare (between normal and mild)
- the occipital lobe shows no structural abnormalities indicative of atrophy | BV |
NIFD_1_S_0102_MR_T1_mprage_S3_DIS3D_br_raw_20170816161439198_36_S596667_I889712 | On a T1-weighted brain MRI of a 71-year-old male subject, we observed:
For the ventricles:
- no observable enlargement or abnormal growth in the 4th ventricle
- severe enlargement of the external csf
- between mild and moderate left enlargement of the lateral ventricle
- between mild and moderate enlargement of the 3rd ventricle
- inf. lateral ventricle appears structurally intact, with no evidence of enlargement
For the cerebral cortex:
- atrophies of insular cortex on anterior insula (moderate) and frontal operculum (mild)
- the temporal lobe shows no structural abnormalities indicative of atrophy
- severe bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (moderate), gyrus rectus (between mild and moderate), middle frontal gyrus (severe), precentral gyrus (severe), sup. frontal gyrus (between mild and moderate) and supplementary motor cortex (moderate)
- mild atrophy of the limbic cortex, more pronounced on the left, with focal volume loss observed in the following subregions: anterior cingulate gyrus (moderate) and middle cingulate gyrus (mild)
- no signs of atrophy detected in the occipital lobe
- focal atrophy of parietal lobe on angular gyrus (between normal and mild)
For the subcortical structures:
- between normal and mild left atrophy of the accumbens
- between normal and mild atrophy of the amygdala
- severe bilateral pallidum atrophy, more pronounced on the left
- severe bilateral ventral dc atrophy, more pronounced on the left
- mild atrophy of the basal forebrain, more pronounced on the left
- severe bilateral putamen atrophy, more pronounced on the left
- severe bilateral thalamus atrophy, more pronounced on the left
- severe bilateral caudate atrophy, more pronounced on the left
- between mild and moderate bilateral hippocampus atrophy | BV |
NIFD_1_S_0064_MR_t1_mprage_S3_DIS3D_br_raw_20111019180821812_6_S125843_I261660 | On a T1-weighted brain MRI of a 66-year-old female subject, we observed:
For the cerebral cortex:
- between normal and mild atrophy of the insular cortex
- no degenerative or atrophic changes noted in the parietal lobe
- no pathological changes consistent with atrophy detected in the occipital lobe
- focal atrophy of limbic cortex on middle cingulate gyrus (between normal and mild)
- atrophies of temporal lobe on planum temporale (mild) and temporal pole (between normal and mild)
- between normal and mild atrophy of the frontal lobe, more pronounced on the right, with focal volume loss observed in the following subregions: sup. frontal gyrus (between moderate and severe), sup. frontal gyrus medial segment (between moderate and severe) and precentral gyrus (mild)
For the subcortical structures:
- the hippocampus shows no structural abnormalities indicative of atrophy
- moderate bilateral putamen atrophy
- no evidence of atrophy or degeneration in the amygdala
- mild right atrophy of the caudate
- between normal and mild left atrophy of the basal forebrain
- between normal and mild atrophy of the accumbens, more pronounced on the right
- ventral dc presents with a healthy appearance, free from atrophy
- the thalamus shows no structural abnormalities indicative of atrophy
- mild right atrophy of the pallidum
For the ventricles:
- between moderate and severe enlargement of the 3rd ventricle
- mild enlargement of the inf. lateral ventricle, more pronounced on the left
- moderate bilateral lateral ventricle enlargement
- external csf maintains its normal volume without signs of enlargement
- no pathological changes consistent with enlargement noted in the 4th ventricle | BV |
NIFD_1_S_0018_MR_t1_mprage__br_raw_20170814165807711_159_S594325_I886781 | On a T1-weighted brain MRI of a 71-year-old male subject, we observed:
For the cerebral cortex:
- no signs of atrophy detected in the occipital lobe
- focal atrophy of insular cortex on anterior insula (between normal and mild)
- focal atrophy of frontal lobe on subcallosal area (mild)
- severe bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: inf. temporal gyrus (severe), middle temporal gyrus (severe) and temporal pole (severe)
- mild atrophy of the parietal lobe, with focal volume loss observed in the following subregions: precuneus (between normal and mild) and sup. parietal lobule (moderate)
- moderate atrophy of the limbic cortex, more pronounced on the left, with focal volume loss observed in the following subregions: entorhinal area (between moderate and severe) and anterior cingulate gyrus (mild)
For the ventricles:
- no enlargement observed in the 3rd ventricle
- 4th ventricle maintains its normal volume without signs of enlargement
- severe bilateral inf. lateral ventricle enlargement
- severe enlargement of the external csf
- no abnormal enlargement observed in the lateral ventricle
For the subcortical structures:
- the putamen shows no structural abnormalities indicative of atrophy
- between moderate and severe bilateral thalamus atrophy, more pronounced on the right
- between moderate and severe bilateral hippocampus atrophy
- mild left atrophy of the caudate
- no pathological changes consistent with atrophy detected in the basal forebrain
- between normal and mild right atrophy of the ventral dc
- severe bilateral amygdala atrophy, more pronounced on the left
- pallidum remains normal, with no signs of tissue loss
- moderate bilateral accumbens atrophy, more pronounced on the right | BV |
NIFD_1_S_0119_MR_t1_mprage_S3_DIS3D_br_raw_20170814185756776_15_S594508_I887000 | On a T1-weighted brain MRI of a 70-year-old female subject, we observed:
For the ventricles:
- 4th ventricle appears structurally intact, with no evidence of enlargement
- between mild and moderate enlargement of the external csf
- no pathological changes consistent with enlargement noted in the lateral ventricle
- no abnormal enlargement observed in the inf. lateral ventricle
- the 3rd ventricle shows no structural abnormalities indicative of enlargement
For the subcortical structures:
- between mild and moderate atrophy of the hippocampus
- between mild and moderate bilateral caudate atrophy
- moderate bilateral ventral dc atrophy
- mild bilateral putamen atrophy
- no observable atrophic alterations in the accumbens
- mild bilateral amygdala atrophy
- between moderate and severe bilateral pallidum atrophy
- moderate atrophy of the basal forebrain, more pronounced on the left
- moderate bilateral thalamus atrophy
For the cerebral cortex:
- limbic cortex remains normal, with no signs of tissue loss
- focal atrophy of insular cortex on anterior insula (between mild and moderate)
- no pathological changes consistent with atrophy detected in the occipital lobe
- mild atrophy of the temporal lobe, with focal volume loss observed in the following subregions: fusiform gyrus (between normal and mild)
- mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: middle frontal gyrus (mild), precentral gyrus (between mild and moderate) and sup. frontal gyrus medial segment (mild)
- atrophies of parietal lobe on postcentral gyrus (moderate) and precuneus (between normal and mild) | BV |
NIFD_1_S_0039_MR_t1_mprage_S9_DIS3D_br_raw_20110422210646858_48_S105044_I228811 | On a T1-weighted brain MRI of a 67-year-old male subject, we observed:
For the ventricles:
- severe bilateral lateral ventricle enlargement
- severe bilateral inf. lateral ventricle enlargement, more pronounced on the right
- no signs of enlargement detected in the 4th ventricle
- severe enlargement of the external csf
- no signs of enlargement detected in the 3rd ventricle
For the cerebral cortex:
- severe bilateral insular cortex atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (severe) and frontal operculum (moderate)
- focal atrophy of parietal lobe on angular gyrus (mild)
- severe bilateral frontal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: frontal pole (severe), gyrus rectus (severe), opercular inf. frontal gyrus (severe), orbital inf. frontal gyrus (moderate), triangular inf. frontal gyrus (between moderate and severe), medial frontal cortex (between moderate and severe), middle frontal gyrus (severe), anterior orbital gyrus (severe), lateral orbital gyrus (severe), medial orbital gyrus (severe), posterior orbital gyrus (severe), precentral gyrus (between mild and moderate), sup. frontal gyrus (severe), sup. frontal gyrus medial segment (severe) and supplementary motor cortex (moderate)
- severe bilateral limbic cortex atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: entorhinal area (moderate), anterior cingulate gyrus (severe) and middle cingulate gyrus (between mild and moderate)
- the occipital lobe shows no structural abnormalities indicative of atrophy
- no signs of atrophy detected in the temporal lobe
For the subcortical structures:
- severe bilateral amygdala atrophy, more pronounced on the right
- the basal forebrain shows no structural abnormalities indicative of atrophy
- mild right atrophy of the ventral dc
- moderate atrophy of the thalamus, more pronounced on the right
- severe bilateral putamen atrophy, more pronounced on the right
- severe bilateral caudate atrophy, more pronounced on the right
- severe bilateral accumbens atrophy, more pronounced on the right
- severe bilateral hippocampus atrophy, more pronounced on the right
- between moderate and severe atrophy of the pallidum, more pronounced on the right | BV |
NIFD_1_S_0032_MR_t1_mprage_S41_DIS3D__br_raw_20110514204129592_155_S108946_I235070 | On a T1-weighted brain MRI of a 60-year-old male subject, we observed:
For the cerebral cortex:
- severe bilateral frontal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: opercular inf. frontal gyrus (mild), middle frontal gyrus (severe), posterior orbital gyrus (mild), precentral gyrus (between moderate and severe) and orbital inf. frontal gyrus (between normal and mild)
- focal atrophy of occipital lobe on cuneus (moderate)
- between mild and moderate atrophy of the limbic cortex, with focal volume loss observed in the following subregions: anterior cingulate gyrus (between moderate and severe) and middle cingulate gyrus (mild)
- parietal lobe maintains its normal morphology without atrophic features
- focal atrophy of temporal lobe on temporal pole (between moderate and severe)
- between mild and moderate atrophy of the insular cortex, with focal volume loss observed in the following subregions: anterior insula (severe) and frontal operculum (between normal and mild)
For the ventricles:
- severe enlargement of the external csf
- between normal and mild enlargement of the lateral ventricle
- no signs of enlargement detected in the 3rd ventricle
- the 4th ventricle shows no structural abnormalities indicative of enlargement
- mild left enlargement of the inf. lateral ventricle
For the subcortical structures:
- moderate bilateral ventral dc atrophy, more pronounced on the left
- between normal and mild atrophy of the putamen, more pronounced on the left
- between moderate and severe bilateral pallidum atrophy, more pronounced on the left
- mild left atrophy of the caudate
- between moderate and severe bilateral accumbens atrophy, more pronounced on the left
- basal forebrain maintains its normal morphology without atrophic features
- mild atrophy of the hippocampus, more pronounced on the left
- between mild and moderate atrophy of the thalamus, more pronounced on the left
- moderate bilateral amygdala atrophy, more pronounced on the left | BV |
NIFD_1_S_0091_MR_T1_mprage_S3_DIS3D_br_raw_20170817104021048_43_S597455_I890811 | On a T1-weighted brain MRI of a 57-year-old male subject, we observed:
For the cerebral cortex:
- occipital lobe appears structurally intact with no atrophic changes
- focal atrophy of parietal lobe on postcentral gyrus (between normal and mild)
- atrophies of temporal lobe on planum temporale (mild) and transverse temporal gyrus (mild)
- severe bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: posterior insula (severe), central operculum (between normal and mild) and parietal operculum (moderate)
- atrophies of limbic cortex on entorhinal area (between normal and mild) and posterior cingulate gyrus (moderate)
- atrophies of frontal lobe on anterior orbital gyrus (moderate) and posterior orbital gyrus (between normal and mild)
For the ventricles:
- between normal and mild enlargement of the 3rd ventricle
- mild right enlargement of the lateral ventricle
- inf. lateral ventricle remains within normal size parameters, with no enlargement detected
- external csf appears structurally intact, with no evidence of enlargement
- the 4th ventricle shows no structural abnormalities indicative of enlargement
For the subcortical structures:
- ventral dc presents with a healthy appearance, free from atrophy
- amygdala remains normal, with no signs of tissue loss
- basal forebrain maintains its normal morphology without atrophic features
- no observable atrophic alterations in the caudate
- pallidum remains normal, with no signs of tissue loss
- severe bilateral thalamus atrophy
- no observable atrophic alterations in the accumbens
- putamen presents with a healthy appearance, free from atrophy
- no pathological changes consistent with atrophy detected in the hippocampus | BV |
NIFD_1_S_0056_MR_t1_mprage_S3_DIS3D_br_raw_20111019194910586_85_S125860_I261681 | On a T1-weighted brain MRI of a 59-year-old male subject, we observed:
For the ventricles:
- no abnormal enlargement observed in the 4th ventricle
- severe bilateral lateral ventricle enlargement
- no signs of enlargement detected in the external csf
- 3rd ventricle remains within normal size parameters, with no enlargement detected
- moderate bilateral inf. lateral ventricle enlargement
For the subcortical structures:
- between normal and mild atrophy of the ventral dc, more pronounced on the left
- basal forebrain presents with a healthy appearance, free from atrophy
- moderate bilateral amygdala atrophy
- between mild and moderate bilateral pallidum atrophy
- no observable atrophic alterations in the putamen
- severe bilateral thalamus atrophy, more pronounced on the left
- between mild and moderate atrophy of the hippocampus
- moderate bilateral caudate atrophy, more pronounced on the left
- moderate bilateral accumbens atrophy
For the cerebral cortex:
- atrophies of insular cortex on central operculum (between normal and mild) and parietal operculum (between moderate and severe)
- focal atrophy of temporal lobe on planum polare (mild)
- moderate atrophy of the parietal lobe, with focal volume loss observed in the following subregions: precuneus (between mild and moderate) and supramarginal gyrus (mild)
- mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: gyrus rectus (mild), posterior orbital gyrus (between mild and moderate) and sup. frontal gyrus (between moderate and severe)
- occipital lobe appears structurally intact with no atrophic changes
- focal atrophy of limbic cortex on anterior cingulate gyrus (between normal and mild) | BV |
NIFD_1_S_0085_MR_T1_mprage_S3_DIS3D_br_raw_20120307000133150_31_S143023_I288641 | On a T1-weighted brain MRI of a 47-year-old female subject, we observed:
For the subcortical structures:
- between moderate and severe bilateral hippocampus atrophy
- mild atrophy of the pallidum, more pronounced on the left
- between normal and mild atrophy of the ventral dc, more pronounced on the left
- accumbens presents with a healthy appearance, free from atrophy
- basal forebrain remains normal, with no signs of tissue loss
- between normal and mild left atrophy of the amygdala
- between moderate and severe atrophy of the thalamus, more pronounced on the left
- between normal and mild atrophy of the caudate, more pronounced on the left
- between normal and mild left atrophy of the putamen
For the ventricles:
- severe enlargement of the external csf
- no signs of enlargement detected in the lateral ventricle
- no signs of enlargement detected in the inf. lateral ventricle
- moderate enlargement of the 3rd ventricle
- the 4th ventricle shows no structural abnormalities indicative of enlargement
For the cerebral cortex:
- limbic cortex appears structurally intact with no atrophic changes
- no signs of atrophy detected in the insular cortex
- focal atrophy of parietal lobe on precuneus (between normal and mild)
- focal atrophy of temporal lobe on temporal pole (between moderate and severe)
- occipital lobe appears structurally intact with no atrophic changes
- mild atrophy of the frontal lobe, more pronounced on the left, with focal volume loss observed in the following subregions: middle frontal gyrus (between moderate and severe), lateral orbital gyrus (between normal and mild) and sup. frontal gyrus medial segment (between normal and mild) | BV |
NIFD_1_S_0209_MR_T1_mprage_S3_DIS3D_br_raw_20140901123615201_24_S229648_I442043 | On a T1-weighted brain MRI of a 58-year-old female subject, we observed:
For the cerebral cortex:
- atrophies of insular cortex on anterior insula (mild) and frontal operculum (between mild and moderate)
- focal atrophy of temporal lobe on temporal pole (between mild and moderate)
- occipital lobe maintains its normal morphology without atrophic features
- moderate bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (moderate) and parahippocampal gyrus (between normal and mild)
- severe bilateral frontal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: frontal pole (mild), opercular inf. frontal gyrus (severe), orbital inf. frontal gyrus (between normal and mild), triangular inf. frontal gyrus (between moderate and severe), medial frontal cortex (mild), middle frontal gyrus (moderate), posterior orbital gyrus (between mild and moderate), sup. frontal gyrus (between moderate and severe) and sup. frontal gyrus medial segment (between normal and mild)
- no signs of atrophy detected in the parietal lobe
For the ventricles:
- between mild and moderate enlargement of the external csf
- between moderate and severe bilateral lateral ventricle enlargement
- no pathological changes consistent with enlargement noted in the 4th ventricle
- severe enlargement of the 3rd ventricle
- moderate bilateral inf. lateral ventricle enlargement
For the subcortical structures:
- between normal and mild right atrophy of the pallidum
- no degenerative or atrophic changes noted in the ventral dc
- between moderate and severe bilateral putamen atrophy, more pronounced on the right
- severe bilateral caudate atrophy
- no degenerative or atrophic changes noted in the basal forebrain
- between mild and moderate bilateral accumbens atrophy
- between mild and moderate bilateral amygdala atrophy
- mild bilateral thalamus atrophy
- hippocampus maintains its normal morphology without atrophic features | BV |
NIFD_2_S_0006_MR_MT1__GradWarp__N3m_Br_20111229185330471_S133333_I274726 | On a T1-weighted brain MRI of a 64-year-old male subject, we observed:
For the cerebral cortex:
- focal atrophy of occipital lobe on occipital fusiform gyrus (moderate)
- severe atrophy of the temporal lobe, more pronounced on the left, with focal volume loss observed in the following subregions: inf. temporal gyrus (severe), temporal pole (moderate), planum temporale (mild), middle temporal gyrus (between moderate and severe) and sup. temporal gyrus (moderate)
- insular cortex remains normal, with no signs of tissue loss
- between moderate and severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (moderate), anterior cingulate gyrus (between normal and mild), middle cingulate gyrus (between normal and mild) and parahippocampal gyrus (between normal and mild)
- focal atrophy of frontal lobe on gyrus rectus (moderate)
- mild atrophy of the parietal lobe, more pronounced on the left, with focal volume loss observed in the following subregions: angular gyrus (between normal and mild)
For the ventricles:
- severe enlargement of the external csf
- severe enlargement of the inf. lateral ventricle, more pronounced on the left
- no pathological changes consistent with enlargement noted in the 3rd ventricle
- no signs of enlargement detected in the 4th ventricle
- mild enlargement of the lateral ventricle
For the subcortical structures:
- between moderate and severe bilateral caudate atrophy, more pronounced on the left
- basal forebrain maintains its normal morphology without atrophic features
- severe bilateral hippocampus atrophy, more pronounced on the left
- accumbens presents with a healthy appearance, free from atrophy
- moderate left atrophy of the thalamus
- between moderate and severe left atrophy of the putamen
- between normal and mild left atrophy of the pallidum
- between mild and moderate bilateral ventral dc atrophy, more pronounced on the left
- severe bilateral amygdala atrophy, more pronounced on the left | BV |
NIFD_1_S_0333_MR_T1_mprage_S3_DIS3D_br_raw_20170628211504795_43_S577375_I866968 | On a T1-weighted brain MRI of a 65-year-old male subject, we observed:
For the ventricles:
- between normal and mild right enlargement of the lateral ventricle
- no signs of enlargement detected in the external csf
- the 3rd ventricle shows no structural abnormalities indicative of enlargement
- no observable enlargement or abnormal growth in the 4th ventricle
- mild enlargement of the inf. lateral ventricle, more pronounced on the right
For the cerebral cortex:
- occipital lobe presents with a healthy appearance, free from atrophy
- mild atrophy of the limbic cortex, with focal volume loss observed in the following subregions: anterior cingulate gyrus (mild) and middle cingulate gyrus (between mild and moderate)
- focal atrophy of insular cortex on anterior insula (between moderate and severe)
- focal atrophy of temporal lobe on inf. temporal gyrus (between mild and moderate)
- severe atrophy of the frontal lobe, more pronounced on the right, with focal volume loss observed in the following subregions: gyrus rectus (moderate), middle frontal gyrus (moderate), posterior orbital gyrus (between normal and mild), sup. frontal gyrus (between moderate and severe) and sup. frontal gyrus medial segment (between moderate and severe)
- no signs of atrophy detected in the parietal lobe
For the subcortical structures:
- no degenerative or atrophic changes noted in the thalamus
- accumbens presents with a healthy appearance, free from atrophy
- ventral dc maintains its normal morphology without atrophic features
- basal forebrain presents with a healthy appearance, free from atrophy
- no observable atrophic alterations in the hippocampus
- between normal and mild atrophy of the amygdala, more pronounced on the right
- between moderate and severe bilateral caudate atrophy, more pronounced on the right
- mild right atrophy of the pallidum
- moderate bilateral putamen atrophy, more pronounced on the right | BV |
NIFD_1_S_0102_MR_T1_mprage_S3_DIS3D_br_raw_20170816161439198_36_S596667_I889712 | On a T1-weighted brain MRI of a 71-year-old male subject, we observed:
For the cerebral cortex:
- severe bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (moderate), gyrus rectus (between mild and moderate), middle frontal gyrus (severe), precentral gyrus (severe), sup. frontal gyrus (between mild and moderate) and supplementary motor cortex (moderate)
- atrophies of insular cortex on anterior insula (moderate) and frontal operculum (mild)
- mild atrophy of the limbic cortex, more pronounced on the left, with focal volume loss observed in the following subregions: anterior cingulate gyrus (moderate) and middle cingulate gyrus (mild)
- focal atrophy of parietal lobe on angular gyrus (between normal and mild)
- no observable atrophic alterations in the temporal lobe
- occipital lobe maintains its normal morphology without atrophic features
For the subcortical structures:
- mild atrophy of the basal forebrain, more pronounced on the left
- between mild and moderate bilateral hippocampus atrophy
- severe bilateral caudate atrophy, more pronounced on the left
- between normal and mild atrophy of the amygdala
- severe bilateral thalamus atrophy, more pronounced on the left
- severe bilateral ventral dc atrophy, more pronounced on the left
- between normal and mild left atrophy of the accumbens
- severe bilateral putamen atrophy, more pronounced on the left
- severe bilateral pallidum atrophy, more pronounced on the left
For the ventricles:
- between mild and moderate enlargement of the 3rd ventricle
- severe enlargement of the external csf
- between mild and moderate left enlargement of the lateral ventricle
- no abnormal enlargement observed in the 4th ventricle
- inf. lateral ventricle is free from enlargement or excessive growth | BV |
NIFD_2_S_0029_MR_MT1__GradWarp__N3m_Br_20130103113440420_S178016_I353168 | On a T1-weighted brain MRI of a 66-year-old male subject, we observed:
For the cerebral cortex:
- between moderate and severe atrophy of the temporal lobe, more pronounced on the left, with focal volume loss observed in the following subregions: middle temporal gyrus (moderate) and temporal pole (between moderate and severe)
- focal atrophy of occipital lobe on cuneus (mild)
- severe bilateral frontal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: frontal pole (between moderate and severe), gyrus rectus (severe), opercular inf. frontal gyrus (severe), orbital inf. frontal gyrus (severe), medial frontal cortex (severe), middle frontal gyrus (severe), anterior orbital gyrus (between moderate and severe), lateral orbital gyrus (severe), medial orbital gyrus (severe), posterior orbital gyrus (severe), precentral gyrus medial segment (moderate), subcallosal area (between moderate and severe), sup. frontal gyrus (between mild and moderate) and sup. frontal gyrus medial segment (severe)
- severe bilateral limbic cortex atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: entorhinal area (moderate) and anterior cingulate gyrus (severe)
- severe bilateral insular cortex atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (between normal and mild) and frontal operculum (moderate)
- no evidence of atrophy or degeneration in the parietal lobe
For the subcortical structures:
- no observable atrophic alterations in the ventral dc
- thalamus presents with a healthy appearance, free from atrophy
- severe bilateral amygdala atrophy, more pronounced on the left
- moderate atrophy of the putamen, more pronounced on the left
- severe bilateral caudate atrophy, more pronounced on the left
- severe bilateral accumbens atrophy, more pronounced on the left
- no pathological changes consistent with atrophy detected in the pallidum
- mild left atrophy of the hippocampus
- basal forebrain presents with a healthy appearance, free from atrophy
For the ventricles:
- moderate enlargement of the 3rd ventricle
- severe enlargement of the external csf
- severe bilateral inf. lateral ventricle enlargement, more pronounced on the left
- no enlargement observed in the 4th ventricle
- severe bilateral lateral ventricle enlargement | BV |
NIFD_1_S_0040_MR_t1_mprage_S3_DIS3D_br_raw_20150522131343256_7_S261234_I494492 | On a T1-weighted brain MRI of a 71-year-old female subject, we observed:
For the cerebral cortex:
- focal atrophy of parietal lobe on precuneus (between normal and mild)
- severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (severe), middle cingulate gyrus (moderate), posterior cingulate gyrus (between normal and mild) and parahippocampal gyrus (between normal and mild)
- occipital lobe presents with a healthy appearance, free from atrophy
- severe bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (mild), frontal operculum (moderate) and parietal operculum (moderate)
- severe bilateral frontal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: frontal pole (severe), gyrus rectus (severe), opercular inf. frontal gyrus (between moderate and severe), triangular inf. frontal gyrus (severe), medial frontal cortex (moderate), middle frontal gyrus (severe), lateral orbital gyrus (between mild and moderate), medial orbital gyrus (moderate), posterior orbital gyrus (moderate), sup. frontal gyrus (between moderate and severe), sup. frontal gyrus medial segment (moderate) and precentral gyrus (mild)
- atrophies of temporal lobe on planum polare (between normal and mild) and sup. temporal gyrus (between normal and mild)
For the subcortical structures:
- severe bilateral thalamus atrophy, more pronounced on the left
- basal forebrain appears structurally intact with no atrophic changes
- severe bilateral pallidum atrophy, more pronounced on the left
- severe bilateral putamen atrophy, more pronounced on the left
- severe bilateral accumbens atrophy, more pronounced on the left
- mild atrophy of the hippocampus, more pronounced on the left
- between moderate and severe bilateral amygdala atrophy
- moderate bilateral ventral dc atrophy
- severe bilateral caudate atrophy, more pronounced on the left
For the ventricles:
- severe bilateral inf. lateral ventricle enlargement, more pronounced on the left
- severe bilateral lateral ventricle enlargement
- severe enlargement of the external csf
- moderate enlargement of the 3rd ventricle
- no pathological changes consistent with enlargement noted in the 4th ventricle | BV |
NIFD_2_S_0002_MR_MT1__GradWarp__N3m_Br_20111229184614074_S133938_I274719 | On a T1-weighted brain MRI of a 64-year-old male subject, we observed:
For the ventricles:
- between moderate and severe enlargement of the lateral ventricle, more pronounced on the right
- moderate enlargement of the external csf
- severe bilateral inf. lateral ventricle enlargement, more pronounced on the right
- severe enlargement of the 3rd ventricle
- no pathological changes consistent with enlargement noted in the 4th ventricle
For the cerebral cortex:
- focal atrophy of parietal lobe on angular gyrus (between normal and mild)
- severe bilateral frontal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: frontal pole (severe), gyrus rectus (severe), opercular inf. frontal gyrus (moderate), medial frontal cortex (between mild and moderate), middle frontal gyrus (severe), anterior orbital gyrus (severe), lateral orbital gyrus (severe), medial orbital gyrus (between moderate and severe), posterior orbital gyrus (moderate), sup. frontal gyrus (between moderate and severe), sup. frontal gyrus medial segment (severe) and triangular inf. frontal gyrus (between normal and mild)
- atrophies of temporal lobe on temporal pole (between normal and mild) and middle temporal gyrus (between normal and mild)
- moderate atrophy of the limbic cortex, more pronounced on the right, with focal volume loss observed in the following subregions: anterior cingulate gyrus (severe)
- occipital lobe remains normal, with no signs of tissue loss
- severe atrophy of the insular cortex, more pronounced on the right, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (between normal and mild) and frontal operculum (between moderate and severe)
For the subcortical structures:
- moderate atrophy of the thalamus, more pronounced on the right
- between normal and mild atrophy of the ventral dc, more pronounced on the right
- amygdala presents with a healthy appearance, free from atrophy
- no evidence of atrophy or degeneration in the basal forebrain
- between mild and moderate atrophy of the hippocampus, more pronounced on the right
- severe bilateral putamen atrophy, more pronounced on the right
- severe bilateral caudate atrophy, more pronounced on the right
- severe bilateral pallidum atrophy, more pronounced on the right
- severe bilateral accumbens atrophy, more pronounced on the right | BV |
NIFD_1_S_0039_MR_t1_mprage_S9_DIS3D_br_raw_20110422210646858_48_S105044_I228811 | On a T1-weighted brain MRI of a 67-year-old male subject, we observed:
For the cerebral cortex:
- temporal lobe maintains its normal morphology without atrophic features
- focal atrophy of parietal lobe on angular gyrus (mild)
- severe bilateral limbic cortex atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: entorhinal area (moderate), anterior cingulate gyrus (severe) and middle cingulate gyrus (between mild and moderate)
- occipital lobe remains normal, with no signs of tissue loss
- severe bilateral insular cortex atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (severe) and frontal operculum (moderate)
- severe bilateral frontal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: frontal pole (severe), gyrus rectus (severe), opercular inf. frontal gyrus (severe), orbital inf. frontal gyrus (moderate), triangular inf. frontal gyrus (between moderate and severe), medial frontal cortex (between moderate and severe), middle frontal gyrus (severe), anterior orbital gyrus (severe), lateral orbital gyrus (severe), medial orbital gyrus (severe), posterior orbital gyrus (severe), precentral gyrus (between mild and moderate), sup. frontal gyrus (severe), sup. frontal gyrus medial segment (severe) and supplementary motor cortex (moderate)
For the ventricles:
- severe bilateral inf. lateral ventricle enlargement, more pronounced on the right
- 3rd ventricle remains within normal size parameters, with no enlargement detected
- severe bilateral lateral ventricle enlargement
- severe enlargement of the external csf
- 4th ventricle maintains its normal volume without signs of enlargement
For the subcortical structures:
- severe bilateral caudate atrophy, more pronounced on the right
- severe bilateral amygdala atrophy, more pronounced on the right
- mild right atrophy of the ventral dc
- moderate atrophy of the thalamus, more pronounced on the right
- basal forebrain appears structurally intact with no atrophic changes
- severe bilateral accumbens atrophy, more pronounced on the right
- severe bilateral putamen atrophy, more pronounced on the right
- between moderate and severe atrophy of the pallidum, more pronounced on the right
- severe bilateral hippocampus atrophy, more pronounced on the right | BV |
NIFD_2_S_0027_MR_MT1__GradWarp__N3m_Br_20130103113648528_S177998_I353170 | On a T1-weighted brain MRI of a 58-year-old female subject, we observed:
For the cerebral cortex:
- atrophies of frontal lobe on lateral orbital gyrus (moderate) and opercular inf. frontal gyrus (between normal and mild)
- focal atrophy of occipital lobe on cuneus (between normal and mild)
- severe bilateral temporal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: fusiform gyrus (moderate), middle temporal gyrus (moderate), sup. temporal gyrus (between normal and mild) and temporal pole (severe)
- between moderate and severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (severe) and parahippocampal gyrus (severe)
- parietal lobe remains normal, with no signs of tissue loss
- moderate bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe) and posterior insula (between normal and mild)
For the ventricles:
- between normal and mild enlargement of the inf. lateral ventricle, more pronounced on the left
- no pathological changes consistent with enlargement noted in the 3rd ventricle
- severe enlargement of the external csf
- the lateral ventricle shows no structural abnormalities indicative of enlargement
- mild enlargement of the 4th ventricle
For the subcortical structures:
- severe bilateral hippocampus atrophy, more pronounced on the left
- between mild and moderate bilateral putamen atrophy
- no pathological changes consistent with atrophy detected in the caudate
- thalamus presents with a healthy appearance, free from atrophy
- severe bilateral amygdala atrophy
- between mild and moderate atrophy of the accumbens, more pronounced on the right
- between mild and moderate bilateral pallidum atrophy
- no evidence of atrophy or degeneration in the ventral dc
- basal forebrain appears structurally intact with no atrophic changes | BV |
NIFD_2_S_0029_MR_MT1__GradWarp__N3m_Br_20130103113440420_S178016_I353168 | On a T1-weighted brain MRI of a 66-year-old male subject, we observed:
For the ventricles:
- severe bilateral lateral ventricle enlargement
- moderate enlargement of the 3rd ventricle
- severe bilateral inf. lateral ventricle enlargement, more pronounced on the left
- severe enlargement of the external csf
- no enlargement observed in the 4th ventricle
For the subcortical structures:
- no observable atrophic alterations in the pallidum
- no degenerative or atrophic changes noted in the ventral dc
- no degenerative or atrophic changes noted in the thalamus
- no signs of atrophy detected in the basal forebrain
- moderate atrophy of the putamen, more pronounced on the left
- severe bilateral accumbens atrophy, more pronounced on the left
- mild left atrophy of the hippocampus
- severe bilateral amygdala atrophy, more pronounced on the left
- severe bilateral caudate atrophy, more pronounced on the left
For the cerebral cortex:
- severe bilateral frontal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: frontal pole (between moderate and severe), gyrus rectus (severe), opercular inf. frontal gyrus (severe), orbital inf. frontal gyrus (severe), medial frontal cortex (severe), middle frontal gyrus (severe), anterior orbital gyrus (between moderate and severe), lateral orbital gyrus (severe), medial orbital gyrus (severe), posterior orbital gyrus (severe), precentral gyrus medial segment (moderate), subcallosal area (between moderate and severe), sup. frontal gyrus (between mild and moderate) and sup. frontal gyrus medial segment (severe)
- between moderate and severe atrophy of the temporal lobe, more pronounced on the left, with focal volume loss observed in the following subregions: middle temporal gyrus (moderate) and temporal pole (between moderate and severe)
- severe bilateral limbic cortex atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: entorhinal area (moderate) and anterior cingulate gyrus (severe)
- no observable atrophic alterations in the parietal lobe
- focal atrophy of occipital lobe on cuneus (mild)
- severe bilateral insular cortex atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (between normal and mild) and frontal operculum (moderate) | BV |
NIFD_2_S_0014_MR_MT1__GradWarp__N3m_Br_20111229191004875_S134530_I274739 | On a T1-weighted brain MRI of a 53-year-old male subject, we observed:
For the cerebral cortex:
- atrophies of occipital lobe on cuneus (between mild and moderate) and middle occipital gyrus (between mild and moderate)
- severe bilateral parietal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: angular gyrus (between normal and mild), precuneus (between normal and mild), sup. parietal lobule (between moderate and severe) and supramarginal gyrus (moderate)
- between normal and mild atrophy of the temporal lobe, more pronounced on the right, with focal volume loss observed in the following subregions: sup. temporal gyrus (between mild and moderate) and temporal pole (mild)
- between normal and mild atrophy of the limbic cortex, with focal volume loss observed in the following subregions: anterior cingulate gyrus (between mild and moderate)
- severe bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: gyrus rectus (between mild and moderate), opercular inf. frontal gyrus (between normal and mild), middle frontal gyrus (between mild and moderate), lateral orbital gyrus (mild), posterior orbital gyrus (severe) and sup. frontal gyrus (between mild and moderate)
- severe bilateral insular cortex atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: anterior insula (between moderate and severe), central operculum (between moderate and severe) and parietal operculum (between normal and mild)
For the subcortical structures:
- between normal and mild right atrophy of the hippocampus
- between normal and mild atrophy of the thalamus
- between moderate and severe bilateral putamen atrophy
- no degenerative or atrophic changes noted in the ventral dc
- severe bilateral accumbens atrophy, more pronounced on the left
- the basal forebrain shows no structural abnormalities indicative of atrophy
- moderate bilateral amygdala atrophy
- severe bilateral pallidum atrophy
- severe bilateral caudate atrophy
For the ventricles:
- severe bilateral inf. lateral ventricle enlargement
- severe enlargement of the 4th ventricle
- severe bilateral lateral ventricle enlargement
- severe enlargement of the external csf
- moderate enlargement of the 3rd ventricle | BV |
NIFD_1_S_0029_MR_t1_mprage_S4_DIS3D_br_raw_20110209101901199_30_S99286_I216392 | On a T1-weighted brain MRI of a 58-year-old female subject, we observed:
For the subcortical structures:
- severe bilateral amygdala atrophy, more pronounced on the right
- moderate bilateral ventral dc atrophy
- severe bilateral pallidum atrophy, more pronounced on the left
- severe bilateral putamen atrophy, more pronounced on the left
- severe bilateral accumbens atrophy, more pronounced on the left
- severe bilateral caudate atrophy, more pronounced on the left
- moderate bilateral thalamus atrophy
- severe bilateral hippocampus atrophy, more pronounced on the right
- no pathological changes consistent with atrophy detected in the basal forebrain
For the ventricles:
- moderate bilateral lateral ventricle enlargement
- moderate enlargement of the 3rd ventricle
- the 4th ventricle shows no structural abnormalities indicative of enlargement
- external csf appears structurally intact, with no evidence of enlargement
- severe bilateral inf. lateral ventricle enlargement
For the cerebral cortex:
- mild atrophy of the frontal lobe, with focal volume loss observed in the following subregions: gyrus rectus (mild), medial frontal cortex (between normal and mild) and sup. frontal gyrus (moderate)
- moderate bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (severe)
- occipital lobe maintains its normal morphology without atrophic features
- moderate bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe) and frontal operculum (moderate)
- parietal lobe presents with a healthy appearance, free from atrophy
- focal atrophy of temporal lobe on planum polare (between normal and mild) | BV |
NIFD_1_S_0081_MR_T1_mprage_S3_DIS3D_br_raw_20120307021952212_143_S143093_I288731 | On a T1-weighted brain MRI of a 60-year-old male subject, we observed:
For the subcortical structures:
- no evidence of atrophy or degeneration in the thalamus
- mild bilateral accumbens atrophy
- no evidence of atrophy or degeneration in the amygdala
- between moderate and severe bilateral caudate atrophy, more pronounced on the right
- no signs of atrophy detected in the basal forebrain
- no observable atrophic alterations in the ventral dc
- between mild and moderate atrophy of the pallidum, more pronounced on the right
- hippocampus remains normal, with no signs of tissue loss
- moderate bilateral putamen atrophy, more pronounced on the right
For the cerebral cortex:
- no degenerative or atrophic changes noted in the parietal lobe
- focal atrophy of insular cortex on frontal operculum (between mild and moderate)
- moderate atrophy of the frontal lobe, more pronounced on the right, with focal volume loss observed in the following subregions: middle frontal gyrus (between normal and mild), posterior orbital gyrus (moderate), sup. frontal gyrus (between normal and mild) and opercular inf. frontal gyrus (mild)
- no observable atrophic alterations in the occipital lobe
- focal atrophy of limbic cortex on anterior cingulate gyrus (moderate)
- temporal lobe appears structurally intact with no atrophic changes
For the ventricles:
- no enlargement observed in the 3rd ventricle
- mild right enlargement of the lateral ventricle
- severe enlargement of the external csf
- mild enlargement of the inf. lateral ventricle
- 4th ventricle remains within normal size parameters, with no enlargement detected | BV |
NIFD_1_S_0091_MR_T1_mprage_S3_DIS3D_br_raw_20170817104021048_43_S597455_I890811 | On a T1-weighted brain MRI of a 57-year-old male subject, we observed:
For the cerebral cortex:
- focal atrophy of parietal lobe on postcentral gyrus (between normal and mild)
- atrophies of limbic cortex on entorhinal area (between normal and mild) and posterior cingulate gyrus (moderate)
- atrophies of temporal lobe on planum temporale (mild) and transverse temporal gyrus (mild)
- atrophies of frontal lobe on anterior orbital gyrus (moderate) and posterior orbital gyrus (between normal and mild)
- severe bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: posterior insula (severe), central operculum (between normal and mild) and parietal operculum (moderate)
- no signs of atrophy detected in the occipital lobe
For the ventricles:
- mild right enlargement of the lateral ventricle
- no signs of enlargement detected in the inf. lateral ventricle
- external csf appears structurally intact, with no evidence of enlargement
- between normal and mild enlargement of the 3rd ventricle
- no pathological changes consistent with enlargement noted in the 4th ventricle
For the subcortical structures:
- no evidence of atrophy or degeneration in the accumbens
- no evidence of atrophy or degeneration in the ventral dc
- no evidence of atrophy or degeneration in the caudate
- no degenerative or atrophic changes noted in the amygdala
- no evidence of atrophy or degeneration in the hippocampus
- putamen presents with a healthy appearance, free from atrophy
- no pathological changes consistent with atrophy detected in the pallidum
- no pathological changes consistent with atrophy detected in the basal forebrain
- severe bilateral thalamus atrophy | BV |
NIFD_1_S_0333_MR_T1_mprage_S3_DIS3D_br_raw_20170628211504795_43_S577375_I866968 | On a T1-weighted brain MRI of a 65-year-old male subject, we observed:
For the cerebral cortex:
- parietal lobe remains normal, with no signs of tissue loss
- no evidence of atrophy or degeneration in the occipital lobe
- mild atrophy of the limbic cortex, with focal volume loss observed in the following subregions: anterior cingulate gyrus (mild) and middle cingulate gyrus (between mild and moderate)
- focal atrophy of temporal lobe on inf. temporal gyrus (between mild and moderate)
- severe atrophy of the frontal lobe, more pronounced on the right, with focal volume loss observed in the following subregions: gyrus rectus (moderate), middle frontal gyrus (moderate), posterior orbital gyrus (between normal and mild), sup. frontal gyrus (between moderate and severe) and sup. frontal gyrus medial segment (between moderate and severe)
- focal atrophy of insular cortex on anterior insula (between moderate and severe)
For the ventricles:
- external csf maintains its normal volume without signs of enlargement
- 3rd ventricle is free from enlargement or excessive growth
- between normal and mild right enlargement of the lateral ventricle
- no abnormal enlargement observed in the 4th ventricle
- mild enlargement of the inf. lateral ventricle, more pronounced on the right
For the subcortical structures:
- thalamus remains normal, with no signs of tissue loss
- ventral dc maintains its normal morphology without atrophic features
- hippocampus presents with a healthy appearance, free from atrophy
- no degenerative or atrophic changes noted in the basal forebrain
- between moderate and severe bilateral caudate atrophy, more pronounced on the right
- mild right atrophy of the pallidum
- between normal and mild atrophy of the amygdala, more pronounced on the right
- accumbens remains normal, with no signs of tissue loss
- moderate bilateral putamen atrophy, more pronounced on the right | BV |
NIFD_2_S_0032_MR_MT1__GradWarp__N3m_Br_20130613083444087_S191547_I376358 | On a T1-weighted brain MRI of a 58-year-old male subject, we observed:
For the cerebral cortex:
- no pathological changes consistent with atrophy detected in the frontal lobe
- no degenerative or atrophic changes noted in the limbic cortex
- focal atrophy of temporal lobe on inf. temporal gyrus (mild)
- focal atrophy of insular cortex on parietal operculum (between normal and mild)
- focal atrophy of occipital lobe on sup. occipital gyrus (between mild and moderate)
- no degenerative or atrophic changes noted in the parietal lobe
For the subcortical structures:
- no signs of atrophy detected in the pallidum
- no observable atrophic alterations in the ventral dc
- accumbens appears structurally intact with no atrophic changes
- thalamus presents with a healthy appearance, free from atrophy
- no evidence of atrophy or degeneration in the basal forebrain
- between moderate and severe bilateral hippocampus atrophy
- mild atrophy of the amygdala
- no signs of atrophy detected in the putamen
- no degenerative or atrophic changes noted in the caudate
For the ventricles:
- inf. lateral ventricle remains within normal size parameters, with no enlargement detected
- moderate enlargement of the external csf
- no abnormal enlargement observed in the 3rd ventricle
- 4th ventricle remains within normal size parameters, with no enlargement detected
- lateral ventricle maintains its normal volume without signs of enlargement | BV |
NIFD_1_S_0011_MR_t1_mprage_S3_DIS3D_br_raw_20110203102701100_95_S98797_I215662 | On a T1-weighted brain MRI of a 60-year-old male subject, we observed:
For the ventricles:
- the 4th ventricle shows no structural abnormalities indicative of enlargement
- severe enlargement of the 3rd ventricle
- no enlargement observed in the lateral ventricle
- moderate enlargement of the external csf
- mild enlargement of the inf. lateral ventricle, more pronounced on the right
For the cerebral cortex:
- severe bilateral frontal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: gyrus rectus (between moderate and severe), medial frontal cortex (between normal and mild), lateral orbital gyrus (between normal and mild), medial orbital gyrus (moderate), posterior orbital gyrus (between mild and moderate), precentral gyrus medial segment (between normal and mild), sup. frontal gyrus medial segment (between mild and moderate) and supplementary motor cortex (between normal and mild)
- focal atrophy of parietal lobe on postcentral gyrus (between mild and moderate)
- focal atrophy of temporal lobe on temporal pole (between normal and mild)
- no degenerative or atrophic changes noted in the occipital lobe
- severe bilateral insular cortex atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (between moderate and severe), central operculum (moderate) and frontal operculum (between normal and mild)
- moderate atrophy of the limbic cortex, with focal volume loss observed in the following subregions: anterior cingulate gyrus (between moderate and severe)
For the subcortical structures:
- the pallidum shows no structural abnormalities indicative of atrophy
- moderate bilateral accumbens atrophy, more pronounced on the right
- severe atrophy of the amygdala, more pronounced on the right
- severe bilateral caudate atrophy, more pronounced on the right
- moderate bilateral putamen atrophy, more pronounced on the right
- basal forebrain presents with a healthy appearance, free from atrophy
- no degenerative or atrophic changes noted in the thalamus
- between normal and mild atrophy of the hippocampus, more pronounced on the right
- no evidence of atrophy or degeneration in the ventral dc | BV |
NIFD_2_S_0027_MR_MT1__GradWarp__N3m_Br_20130103113648528_S177998_I353170 | On a T1-weighted brain MRI of a 58-year-old female subject, we observed:
For the ventricles:
- severe enlargement of the external csf
- mild enlargement of the 4th ventricle
- no pathological changes consistent with enlargement noted in the 3rd ventricle
- between normal and mild enlargement of the inf. lateral ventricle, more pronounced on the left
- lateral ventricle remains within normal size parameters, with no enlargement detected
For the cerebral cortex:
- atrophies of frontal lobe on lateral orbital gyrus (moderate) and opercular inf. frontal gyrus (between normal and mild)
- moderate bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe) and posterior insula (between normal and mild)
- severe bilateral temporal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: fusiform gyrus (moderate), middle temporal gyrus (moderate), sup. temporal gyrus (between normal and mild) and temporal pole (severe)
- no pathological changes consistent with atrophy detected in the parietal lobe
- between moderate and severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (severe) and parahippocampal gyrus (severe)
- focal atrophy of occipital lobe on cuneus (between normal and mild)
For the subcortical structures:
- severe bilateral hippocampus atrophy, more pronounced on the left
- severe bilateral amygdala atrophy
- the caudate shows no structural abnormalities indicative of atrophy
- between mild and moderate atrophy of the accumbens, more pronounced on the right
- between mild and moderate bilateral pallidum atrophy
- no pathological changes consistent with atrophy detected in the thalamus
- no degenerative or atrophic changes noted in the ventral dc
- between mild and moderate bilateral putamen atrophy
- no pathological changes consistent with atrophy detected in the basal forebrain | BV |
NIFD_2_S_0004_MR_MT1__GradWarp__N3m_Br_20120105162046732_S133219_I275501 | On a T1-weighted brain MRI of a 66-year-old male subject, we observed:
For the cerebral cortex:
- no signs of atrophy detected in the parietal lobe
- occipital lobe presents with a healthy appearance, free from atrophy
- severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (severe), anterior cingulate gyrus (between moderate and severe), middle cingulate gyrus (moderate) and parahippocampal gyrus (severe)
- severe bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: fusiform gyrus (between moderate and severe), planum polare (moderate), inf. temporal gyrus (severe), middle temporal gyrus (mild) and temporal pole (severe)
- moderate bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: gyrus rectus (severe), medial frontal cortex (between moderate and severe), middle frontal gyrus (moderate), medial orbital gyrus (between moderate and severe) and subcallosal area (mild)
- severe bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (severe) and frontal operculum (between mild and moderate)
For the ventricles:
- severe bilateral inf. lateral ventricle enlargement
- 4th ventricle is free from enlargement or excessive growth
- between moderate and severe enlargement of the 3rd ventricle
- moderate enlargement of the external csf
- between moderate and severe bilateral lateral ventricle enlargement
For the subcortical structures:
- moderate bilateral pallidum atrophy
- severe bilateral putamen atrophy
- ventral dc remains normal, with no signs of tissue loss
- between normal and mild atrophy of the thalamus
- between normal and mild left atrophy of the caudate
- severe bilateral amygdala atrophy, more pronounced on the left
- basal forebrain appears structurally intact with no atrophic changes
- severe bilateral hippocampus atrophy
- severe bilateral accumbens atrophy | BV |
NIFD_1_S_0356_MR_t1_mprage__br_raw_20170628174605905_151_S577026_I866521 | On a T1-weighted brain MRI of a 61-year-old female subject, we observed:
For the cerebral cortex:
- severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (severe) and posterior cingulate gyrus (between normal and mild)
- severe bilateral frontal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: gyrus rectus (severe), opercular inf. frontal gyrus (between moderate and severe), orbital inf. frontal gyrus (between moderate and severe), triangular inf. frontal gyrus (between mild and moderate), medial frontal cortex (severe), middle frontal gyrus (severe), anterior orbital gyrus (between mild and moderate), lateral orbital gyrus (severe), medial orbital gyrus (between moderate and severe), posterior orbital gyrus (between mild and moderate), sup. frontal gyrus (severe) and sup. frontal gyrus medial segment (severe)
- severe atrophy of the temporal lobe, more pronounced on the right, with focal volume loss observed in the following subregions: fusiform gyrus (moderate), sup. temporal gyrus (between mild and moderate) and temporal pole (severe)
- occipital lobe appears structurally intact with no atrophic changes
- between moderate and severe bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe) and frontal operculum (severe)
- no signs of atrophy detected in the parietal lobe
For the subcortical structures:
- basal forebrain remains normal, with no signs of tissue loss
- no pathological changes consistent with atrophy detected in the ventral dc
- between normal and mild atrophy of the caudate, more pronounced on the right
- severe bilateral amygdala atrophy, more pronounced on the right
- thalamus appears structurally intact with no atrophic changes
- between normal and mild right atrophy of the putamen
- severe bilateral accumbens atrophy, more pronounced on the right
- mild atrophy of the hippocampus, more pronounced on the right
- no observable atrophic alterations in the pallidum
For the ventricles:
- severe enlargement of the external csf
- no enlargement observed in the 3rd ventricle
- between mild and moderate enlargement of the inf. lateral ventricle, more pronounced on the right
- 4th ventricle maintains its normal volume without signs of enlargement
- lateral ventricle appears structurally intact, with no evidence of enlargement | BV |
NIFD_2_S_0002_MR_MT1__GradWarp__N3m_Br_20111229184614074_S133938_I274719 | On a T1-weighted brain MRI of a 64-year-old male subject, we observed:
For the ventricles:
- between moderate and severe enlargement of the lateral ventricle, more pronounced on the right
- severe bilateral inf. lateral ventricle enlargement, more pronounced on the right
- 4th ventricle maintains its normal volume without signs of enlargement
- severe enlargement of the 3rd ventricle
- moderate enlargement of the external csf
For the subcortical structures:
- between normal and mild atrophy of the ventral dc, more pronounced on the right
- severe bilateral accumbens atrophy, more pronounced on the right
- no signs of atrophy detected in the amygdala
- severe bilateral putamen atrophy, more pronounced on the right
- moderate atrophy of the thalamus, more pronounced on the right
- between mild and moderate atrophy of the hippocampus, more pronounced on the right
- severe bilateral pallidum atrophy, more pronounced on the right
- the basal forebrain shows no structural abnormalities indicative of atrophy
- severe bilateral caudate atrophy, more pronounced on the right
For the cerebral cortex:
- severe atrophy of the insular cortex, more pronounced on the right, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (between normal and mild) and frontal operculum (between moderate and severe)
- severe bilateral frontal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: frontal pole (severe), gyrus rectus (severe), opercular inf. frontal gyrus (moderate), medial frontal cortex (between mild and moderate), middle frontal gyrus (severe), anterior orbital gyrus (severe), lateral orbital gyrus (severe), medial orbital gyrus (between moderate and severe), posterior orbital gyrus (moderate), sup. frontal gyrus (between moderate and severe), sup. frontal gyrus medial segment (severe) and triangular inf. frontal gyrus (between normal and mild)
- atrophies of temporal lobe on temporal pole (between normal and mild) and middle temporal gyrus (between normal and mild)
- moderate atrophy of the limbic cortex, more pronounced on the right, with focal volume loss observed in the following subregions: anterior cingulate gyrus (severe)
- no degenerative or atrophic changes noted in the occipital lobe
- focal atrophy of parietal lobe on angular gyrus (between normal and mild) | BV |
NIFD_1_S_0029_MR_t1_mprage_S4_DIS3D_br_raw_20110209101901199_30_S99286_I216392 | On a T1-weighted brain MRI of a 58-year-old female subject, we observed:
For the subcortical structures:
- severe bilateral amygdala atrophy, more pronounced on the right
- severe bilateral accumbens atrophy, more pronounced on the left
- severe bilateral pallidum atrophy, more pronounced on the left
- no evidence of atrophy or degeneration in the basal forebrain
- moderate bilateral ventral dc atrophy
- severe bilateral putamen atrophy, more pronounced on the left
- severe bilateral hippocampus atrophy, more pronounced on the right
- severe bilateral caudate atrophy, more pronounced on the left
- moderate bilateral thalamus atrophy
For the cerebral cortex:
- moderate bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe) and frontal operculum (moderate)
- mild atrophy of the frontal lobe, with focal volume loss observed in the following subregions: gyrus rectus (mild), medial frontal cortex (between normal and mild) and sup. frontal gyrus (moderate)
- occipital lobe maintains its normal morphology without atrophic features
- moderate bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (severe)
- parietal lobe maintains its normal morphology without atrophic features
- focal atrophy of temporal lobe on planum polare (between normal and mild)
For the ventricles:
- severe bilateral inf. lateral ventricle enlargement
- external csf is free from enlargement or excessive growth
- 4th ventricle maintains its normal volume without signs of enlargement
- moderate enlargement of the 3rd ventricle
- moderate bilateral lateral ventricle enlargement | BV |
NIFD_1_S_0096_MR_T1_mprage_S3_DIS3D_br_raw_20170817133934845_74_S598211_I891811 | On a T1-weighted brain MRI of a 69-year-old male subject, we observed:
For the subcortical structures:
- the amygdala shows no structural abnormalities indicative of atrophy
- no evidence of atrophy or degeneration in the caudate
- pallidum maintains its normal morphology without atrophic features
- putamen presents with a healthy appearance, free from atrophy
- mild atrophy of the thalamus, more pronounced on the right
- basal forebrain remains normal, with no signs of tissue loss
- no evidence of atrophy or degeneration in the accumbens
- no observable atrophic alterations in the hippocampus
- between normal and mild right atrophy of the ventral dc
For the cerebral cortex:
- focal atrophy of frontal lobe on middle frontal gyrus (mild)
- focal atrophy of occipital lobe on occipital pole (between normal and mild)
- no evidence of atrophy or degeneration in the parietal lobe
- limbic cortex remains normal, with no signs of tissue loss
- no pathological changes consistent with atrophy detected in the temporal lobe
- between normal and mild atrophy of the insular cortex, with focal volume loss observed in the following subregions: frontal operculum (between mild and moderate)
For the ventricles:
- between mild and moderate enlargement of the 3rd ventricle
- no enlargement observed in the external csf
- lateral ventricle remains within normal size parameters, with no enlargement detected
- no signs of enlargement detected in the 4th ventricle
- no enlargement observed in the inf. lateral ventricle | BV |
NIFD_2_S_0002_MR_MT1__GradWarp__N3m_Br_20111229184614074_S133938_I274719 | On a T1-weighted brain MRI of a 64-year-old male subject, we observed:
For the ventricles:
- severe bilateral inf. lateral ventricle enlargement, more pronounced on the right
- between moderate and severe enlargement of the lateral ventricle, more pronounced on the right
- moderate enlargement of the external csf
- no observable enlargement or abnormal growth in the 4th ventricle
- severe enlargement of the 3rd ventricle
For the cerebral cortex:
- severe bilateral frontal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: frontal pole (severe), gyrus rectus (severe), opercular inf. frontal gyrus (moderate), medial frontal cortex (between mild and moderate), middle frontal gyrus (severe), anterior orbital gyrus (severe), lateral orbital gyrus (severe), medial orbital gyrus (between moderate and severe), posterior orbital gyrus (moderate), sup. frontal gyrus (between moderate and severe), sup. frontal gyrus medial segment (severe) and triangular inf. frontal gyrus (between normal and mild)
- atrophies of temporal lobe on temporal pole (between normal and mild) and middle temporal gyrus (between normal and mild)
- severe atrophy of the insular cortex, more pronounced on the right, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (between normal and mild) and frontal operculum (between moderate and severe)
- moderate atrophy of the limbic cortex, more pronounced on the right, with focal volume loss observed in the following subregions: anterior cingulate gyrus (severe)
- focal atrophy of parietal lobe on angular gyrus (between normal and mild)
- no signs of atrophy detected in the occipital lobe
For the subcortical structures:
- basal forebrain presents with a healthy appearance, free from atrophy
- the amygdala shows no structural abnormalities indicative of atrophy
- severe bilateral caudate atrophy, more pronounced on the right
- severe bilateral putamen atrophy, more pronounced on the right
- between normal and mild atrophy of the ventral dc, more pronounced on the right
- severe bilateral pallidum atrophy, more pronounced on the right
- moderate atrophy of the thalamus, more pronounced on the right
- severe bilateral accumbens atrophy, more pronounced on the right
- between mild and moderate atrophy of the hippocampus, more pronounced on the right | BV |
NIFD_1_S_0095_MR_T1_mprage_S3_DIS3D_br_raw_20120819163606804_114_S161475_I324728 | On a T1-weighted brain MRI of a 73-year-old female subject, we observed:
For the ventricles:
- severe enlargement of the 3rd ventricle
- severe bilateral lateral ventricle enlargement
- no enlargement observed in the 4th ventricle
- severe bilateral inf. lateral ventricle enlargement
- no enlargement observed in the external csf
For the subcortical structures:
- severe bilateral caudate atrophy
- basal forebrain remains normal, with no signs of tissue loss
- severe bilateral putamen atrophy
- severe bilateral accumbens atrophy, more pronounced on the left
- between moderate and severe bilateral thalamus atrophy
- severe bilateral amygdala atrophy, more pronounced on the left
- moderate bilateral hippocampus atrophy, more pronounced on the right
- moderate bilateral pallidum atrophy, more pronounced on the left
- ventral dc presents with a healthy appearance, free from atrophy
For the cerebral cortex:
- atrophies of occipital lobe on calcarine cortex (between normal and mild) and occipital pole (between mild and moderate)
- no pathological changes consistent with atrophy detected in the parietal lobe
- no pathological changes consistent with atrophy detected in the temporal lobe
- severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (between mild and moderate), anterior cingulate gyrus (between moderate and severe) and parahippocampal gyrus (between mild and moderate)
- severe bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (moderate), gyrus rectus (moderate), opercular inf. frontal gyrus (between normal and mild), orbital inf. frontal gyrus (moderate), triangular inf. frontal gyrus (between normal and mild), medial frontal cortex (moderate), middle frontal gyrus (severe), anterior orbital gyrus (between normal and mild), medial orbital gyrus (moderate), sup. frontal gyrus (between normal and mild) and sup. frontal gyrus medial segment (between mild and moderate)
- mild atrophy of the insular cortex, with focal volume loss observed in the following subregions: anterior insula (between mild and moderate) | BV |
NIFD_1_S_0040_MR_t1_mprage_S3_DIS3D_br_raw_20150522131343256_7_S261234_I494492 | On a T1-weighted brain MRI of a 71-year-old female subject, we observed:
For the cerebral cortex:
- severe bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (mild), frontal operculum (moderate) and parietal operculum (moderate)
- atrophies of temporal lobe on planum polare (between normal and mild) and sup. temporal gyrus (between normal and mild)
- severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (severe), middle cingulate gyrus (moderate), posterior cingulate gyrus (between normal and mild) and parahippocampal gyrus (between normal and mild)
- severe bilateral frontal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: frontal pole (severe), gyrus rectus (severe), opercular inf. frontal gyrus (between moderate and severe), triangular inf. frontal gyrus (severe), medial frontal cortex (moderate), middle frontal gyrus (severe), lateral orbital gyrus (between mild and moderate), medial orbital gyrus (moderate), posterior orbital gyrus (moderate), sup. frontal gyrus (between moderate and severe), sup. frontal gyrus medial segment (moderate) and precentral gyrus (mild)
- no observable atrophic alterations in the occipital lobe
- focal atrophy of parietal lobe on precuneus (between normal and mild)
For the subcortical structures:
- severe bilateral pallidum atrophy, more pronounced on the left
- the basal forebrain shows no structural abnormalities indicative of atrophy
- between moderate and severe bilateral amygdala atrophy
- moderate bilateral ventral dc atrophy
- mild atrophy of the hippocampus, more pronounced on the left
- severe bilateral thalamus atrophy, more pronounced on the left
- severe bilateral accumbens atrophy, more pronounced on the left
- severe bilateral putamen atrophy, more pronounced on the left
- severe bilateral caudate atrophy, more pronounced on the left
For the ventricles:
- severe enlargement of the external csf
- 4th ventricle maintains its normal volume without signs of enlargement
- severe bilateral lateral ventricle enlargement
- severe bilateral inf. lateral ventricle enlargement, more pronounced on the left
- moderate enlargement of the 3rd ventricle | BV |
NIFD_2_S_0014_MR_MT1__GradWarp__N3m_Br_20111229191004875_S134530_I274739 | On a T1-weighted brain MRI of a 53-year-old male subject, we observed:
For the subcortical structures:
- severe bilateral pallidum atrophy
- no pathological changes consistent with atrophy detected in the ventral dc
- moderate bilateral amygdala atrophy
- between normal and mild right atrophy of the hippocampus
- between normal and mild atrophy of the thalamus
- no degenerative or atrophic changes noted in the basal forebrain
- between moderate and severe bilateral putamen atrophy
- severe bilateral accumbens atrophy, more pronounced on the left
- severe bilateral caudate atrophy
For the cerebral cortex:
- severe bilateral insular cortex atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: anterior insula (between moderate and severe), central operculum (between moderate and severe) and parietal operculum (between normal and mild)
- between normal and mild atrophy of the limbic cortex, with focal volume loss observed in the following subregions: anterior cingulate gyrus (between mild and moderate)
- between normal and mild atrophy of the temporal lobe, more pronounced on the right, with focal volume loss observed in the following subregions: sup. temporal gyrus (between mild and moderate) and temporal pole (mild)
- atrophies of occipital lobe on cuneus (between mild and moderate) and middle occipital gyrus (between mild and moderate)
- severe bilateral parietal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: angular gyrus (between normal and mild), precuneus (between normal and mild), sup. parietal lobule (between moderate and severe) and supramarginal gyrus (moderate)
- severe bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: gyrus rectus (between mild and moderate), opercular inf. frontal gyrus (between normal and mild), middle frontal gyrus (between mild and moderate), lateral orbital gyrus (mild), posterior orbital gyrus (severe) and sup. frontal gyrus (between mild and moderate)
For the ventricles:
- severe bilateral inf. lateral ventricle enlargement
- severe enlargement of the external csf
- severe bilateral lateral ventricle enlargement
- severe enlargement of the 4th ventricle
- moderate enlargement of the 3rd ventricle | BV |
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