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ADNI_130_S_5006_MR_MPRAGE_br_raw_20121130100341274_49_S175869_I348490
On a T1-weighted brain MRI of a 69-year-old female subject, we observed: For the subcortical structures: - ventral dc presents with a healthy appearance, free from atrophy - moderate bilateral hippocampus atrophy - thalamus appears structurally intact with no atrophic changes - moderate bilateral accumbens atrophy, more pronounced on the right - no pathological changes consistent with atrophy detected in the pallidum - putamen presents with a healthy appearance, free from atrophy - caudate presents with a healthy appearance, free from atrophy - basal forebrain presents with a healthy appearance, free from atrophy - between moderate and severe bilateral amygdala atrophy For the cerebral cortex: - focal atrophy of parietal lobe on angular gyrus (mild) - moderate bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: planum temporale (between moderate and severe) - between mild and moderate bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (mild) and parietal operculum (between normal and mild) - moderate bilateral frontal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: gyrus rectus (between mild and moderate), medial frontal cortex (between normal and mild), middle frontal gyrus (mild), medial orbital gyrus (between normal and mild) and sup. frontal gyrus (moderate) - occipital lobe maintains its normal morphology without atrophic features - moderate atrophy of the limbic cortex, with focal volume loss observed in the following subregions: anterior cingulate gyrus (between normal and mild) and posterior cingulate gyrus (between normal and mild) For the ventricles: - inf. lateral ventricle is free from enlargement or excessive growth - no enlargement observed in the lateral ventricle - no observable enlargement or abnormal growth in the 3rd ventricle - no signs of enlargement detected in the 4th ventricle - mild enlargement of the external csf
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ADNI_073_S_4853_MR_MPRAGE_br_raw_20120711181405636_32_S157321_I315948
On a T1-weighted brain MRI of a 71-year-old female subject, we observed: For the cerebral cortex: - no observable atrophic alterations in the occipital lobe - moderate atrophy of the temporal lobe, more pronounced on the right, with focal volume loss observed in the following subregions: middle temporal gyrus (moderate) - no pathological changes consistent with atrophy detected in the parietal lobe - between mild and moderate bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: sup. frontal gyrus (between normal and mild) and sup. frontal gyrus medial segment (between mild and moderate) - atrophies of insular cortex on posterior insula (mild) and central operculum (between normal and mild) - mild atrophy of the limbic cortex For the subcortical structures: - between normal and mild atrophy of the hippocampus, more pronounced on the right - between normal and mild atrophy of the amygdala, more pronounced on the right - between mild and moderate bilateral ventral dc atrophy - between normal and mild atrophy of the accumbens - thalamus remains normal, with no signs of tissue loss - no signs of atrophy detected in the putamen - basal forebrain appears structurally intact with no atrophic changes - no observable atrophic alterations in the caudate - the pallidum shows no structural abnormalities indicative of atrophy For the ventricles: - no pathological changes consistent with enlargement noted in the lateral ventricle - no enlargement observed in the 4th ventricle - between moderate and severe enlargement of the external csf - no pathological changes consistent with enlargement noted in the 3rd ventricle - no enlargement observed in the inf. lateral ventricle
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ADNI_037_S_4879_MR_MPRAGE_br_raw_20120913121552870_142_S167309_I333832
On a T1-weighted brain MRI of a 80-year-old female subject, we observed: For the subcortical structures: - no pathological changes consistent with atrophy detected in the thalamus - basal forebrain appears structurally intact with no atrophic changes - between normal and mild atrophy of the hippocampus - putamen remains normal, with no signs of tissue loss - the caudate shows no structural abnormalities indicative of atrophy - no signs of atrophy detected in the pallidum - between mild and moderate atrophy of the amygdala - ventral dc maintains its normal morphology without atrophic features - the accumbens shows no structural abnormalities indicative of atrophy For the cerebral cortex: - focal atrophy of limbic cortex on entorhinal area (between mild and moderate) - no pathological changes consistent with atrophy detected in the frontal lobe - no pathological changes consistent with atrophy detected in the occipital lobe - no observable atrophic alterations in the insular cortex - temporal lobe maintains its normal morphology without atrophic features - focal atrophy of parietal lobe on sup. parietal lobule (severe) For the ventricles: - between normal and mild enlargement of the inf. lateral ventricle - no signs of enlargement detected in the lateral ventricle - no abnormal enlargement observed in the 3rd ventricle - 4th ventricle appears structurally intact, with no evidence of enlargement - no enlargement observed in the external csf
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ADNI_130_S_4997_MR_MPRAGE_br_raw_20121120141641968_22_S175145_I347410
On a T1-weighted brain MRI of a 61-year-old female subject, we observed: For the ventricles: - no enlargement observed in the 3rd ventricle - inf. lateral ventricle maintains its normal volume without signs of enlargement - 4th ventricle is free from enlargement or excessive growth - external csf maintains its normal volume without signs of enlargement - the lateral ventricle shows no structural abnormalities indicative of enlargement For the subcortical structures: - thalamus maintains its normal morphology without atrophic features - hippocampus remains normal, with no signs of tissue loss - no degenerative or atrophic changes noted in the pallidum - no observable atrophic alterations in the ventral dc - the accumbens shows no structural abnormalities indicative of atrophy - caudate presents with a healthy appearance, free from atrophy - no observable atrophic alterations in the amygdala - no pathological changes consistent with atrophy detected in the putamen - no evidence of atrophy or degeneration in the basal forebrain For the cerebral cortex: - no degenerative or atrophic changes noted in the insular cortex - between normal and mild atrophy of the parietal lobe - focal atrophy of frontal lobe on middle frontal gyrus (mild) - the limbic cortex shows no structural abnormalities indicative of atrophy - no signs of atrophy detected in the temporal lobe - no pathological changes consistent with atrophy detected in the occipital lobe
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ADNI_116_S_4625_MR_MPRAGE_br_raw_20120405131840016_174_S146475_I296138
On a T1-weighted brain MRI of a 64-year-old male subject, we observed: For the subcortical structures: - the pallidum shows no structural abnormalities indicative of atrophy - putamen remains normal, with no signs of tissue loss - no observable atrophic alterations in the thalamus - between normal and mild atrophy of the amygdala - basal forebrain remains normal, with no signs of tissue loss - caudate maintains its normal morphology without atrophic features - hippocampus maintains its normal morphology without atrophic features - no evidence of atrophy or degeneration in the accumbens - the ventral dc shows no structural abnormalities indicative of atrophy For the ventricles: - the 3rd ventricle shows no structural abnormalities indicative of enlargement - no abnormal enlargement observed in the external csf - the inf. lateral ventricle shows no structural abnormalities indicative of enlargement - no abnormal enlargement observed in the 4th ventricle - no enlargement observed in the lateral ventricle For the cerebral cortex: - limbic cortex appears structurally intact with no atrophic changes - no observable atrophic alterations in the insular cortex - no pathological changes consistent with atrophy detected in the temporal lobe - focal atrophy of parietal lobe on precuneus (between normal and mild) - the frontal lobe shows no structural abnormalities indicative of atrophy - the occipital lobe shows no structural abnormalities indicative of atrophy
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ADNI_116_S_4195_MR_MPRAGE_br_raw_20110901175610510_89_S121073_I254248
On a T1-weighted brain MRI of a 63-year-old male subject, we observed: For the ventricles: - no enlargement observed in the lateral ventricle - no signs of enlargement detected in the 3rd ventricle - between normal and mild enlargement of the external csf - the 4th ventricle shows no structural abnormalities indicative of enlargement - the inf. lateral ventricle shows no structural abnormalities indicative of enlargement For the cerebral cortex: - limbic cortex maintains its normal morphology without atrophic features - the insular cortex shows no structural abnormalities indicative of atrophy - parietal lobe remains normal, with no signs of tissue loss - frontal lobe maintains its normal morphology without atrophic features - no observable atrophic alterations in the occipital lobe - between mild and moderate atrophy of the temporal lobe, more pronounced on the right, with focal volume loss observed in the following subregions: inf. temporal gyrus (mild) and temporal pole (between normal and mild) For the subcortical structures: - caudate presents with a healthy appearance, free from atrophy - pallidum remains normal, with no signs of tissue loss - between normal and mild right atrophy of the hippocampus - ventral dc appears structurally intact with no atrophic changes - no observable atrophic alterations in the amygdala - thalamus appears structurally intact with no atrophic changes - no observable atrophic alterations in the putamen - no degenerative or atrophic changes noted in the basal forebrain - accumbens maintains its normal morphology without atrophic features
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ADNI_128_S_5123_MR_MPRAGE_br_raw_20130625131829943_43_S193357_I378115
On a T1-weighted brain MRI of a 74-year-old female subject, we observed: For the ventricles: - 4th ventricle remains within normal size parameters, with no enlargement detected - inf. lateral ventricle remains within normal size parameters, with no enlargement detected - no enlargement observed in the external csf - no observable enlargement or abnormal growth in the lateral ventricle - 3rd ventricle appears structurally intact, with no evidence of enlargement For the subcortical structures: - mild left atrophy of the amygdala - no signs of atrophy detected in the putamen - no observable atrophic alterations in the caudate - pallidum maintains its normal morphology without atrophic features - severe bilateral hippocampus atrophy - basal forebrain remains normal, with no signs of tissue loss - no pathological changes consistent with atrophy detected in the accumbens - no pathological changes consistent with atrophy detected in the thalamus - no degenerative or atrophic changes noted in the ventral dc For the cerebral cortex: - focal atrophy of occipital lobe on inf. occipital gyrus (between normal and mild) - focal atrophy of frontal lobe on precentral gyrus (mild) - limbic cortex presents with a healthy appearance, free from atrophy - moderate bilateral temporal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: fusiform gyrus (mild), sup. temporal gyrus (between normal and mild) and transverse temporal gyrus (mild) - focal atrophy of insular cortex on central operculum (mild) - focal atrophy of parietal lobe on postcentral gyrus (between normal and mild)
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ADNI_027_S_4801_MR_Accelerated_SAG_IR-SPGR__br_raw_20120703090719222_105_S156382_I314033
On a T1-weighted brain MRI of a 78-year-old male subject, we observed: For the ventricles: - no observable enlargement or abnormal growth in the lateral ventricle - between normal and mild enlargement of the 3rd ventricle - moderate bilateral inf. lateral ventricle enlargement - 4th ventricle is free from enlargement or excessive growth - no abnormal enlargement observed in the external csf For the subcortical structures: - ventral dc presents with a healthy appearance, free from atrophy - thalamus maintains its normal morphology without atrophic features - putamen appears structurally intact with no atrophic changes - accumbens appears structurally intact with no atrophic changes - between normal and mild right atrophy of the amygdala - no observable atrophic alterations in the caudate - mild atrophy of the hippocampus, more pronounced on the left - pallidum maintains its normal morphology without atrophic features - basal forebrain appears structurally intact with no atrophic changes For the cerebral cortex: - temporal lobe presents with a healthy appearance, free from atrophy - focal atrophy of occipital lobe on cuneus (moderate) - no degenerative or atrophic changes noted in the parietal lobe - no observable atrophic alterations in the limbic cortex - no observable atrophic alterations in the insular cortex - focal atrophy of frontal lobe on medial frontal cortex (between normal and mild)
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ADNI_036_S_5063_MR_MPRAGE_br_raw_20130118120907075_34_S180473_I355515
On a T1-weighted brain MRI of a 72-year-old female subject, we observed: For the ventricles: - 4th ventricle remains within normal size parameters, with no enlargement detected - no pathological changes consistent with enlargement noted in the 3rd ventricle - lateral ventricle maintains its normal volume without signs of enlargement - between moderate and severe enlargement of the external csf - severe bilateral inf. lateral ventricle enlargement For the cerebral cortex: - mild atrophy of the limbic cortex, with focal volume loss observed in the following subregions: anterior cingulate gyrus (moderate) - between moderate and severe atrophy of the temporal lobe, more pronounced on the left, with focal volume loss observed in the following subregions: middle temporal gyrus (between moderate and severe) and sup. temporal gyrus (between normal and mild) - moderate bilateral occipital lobe atrophy, with focal volume loss observed in the following subregions: calcarine cortex (between normal and mild), lingual gyrus (moderate) and middle occipital gyrus (between moderate and severe) - between mild and moderate bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (moderate) and posterior insula (moderate) - focal atrophy of parietal lobe on angular gyrus (moderate) - no evidence of atrophy or degeneration in the frontal lobe For the subcortical structures: - pallidum remains normal, with no signs of tissue loss - between moderate and severe bilateral accumbens atrophy - no evidence of atrophy or degeneration in the basal forebrain - ventral dc remains normal, with no signs of tissue loss - severe bilateral amygdala atrophy, more pronounced on the left - caudate appears structurally intact with no atrophic changes - hippocampus remains normal, with no signs of tissue loss - mild left atrophy of the putamen - thalamus maintains its normal morphology without atrophic features
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ADNI_130_S_4990_MR_MPRAGE_br_raw_20121029151935426_15_S172518_I342911
On a T1-weighted brain MRI of a 76-year-old female subject, we observed: For the cerebral cortex: - the occipital lobe shows no structural abnormalities indicative of atrophy - mild atrophy of the frontal lobe, with focal volume loss observed in the following subregions: opercular inf. frontal gyrus (moderate), medial orbital gyrus (mild) and sup. frontal gyrus (between normal and mild) - focal atrophy of limbic cortex on anterior cingulate gyrus (between normal and mild) - focal atrophy of temporal lobe on middle temporal gyrus (mild) - no signs of atrophy detected in the insular cortex - parietal lobe appears structurally intact with no atrophic changes For the ventricles: - the 4th ventricle shows no structural abnormalities indicative of enlargement - no enlargement observed in the external csf - between normal and mild left enlargement of the inf. lateral ventricle - between mild and moderate right enlargement of the lateral ventricle - no abnormal enlargement observed in the 3rd ventricle For the subcortical structures: - between normal and mild right atrophy of the putamen - between normal and mild atrophy of the amygdala - basal forebrain appears structurally intact with no atrophic changes - hippocampus maintains its normal morphology without atrophic features - ventral dc presents with a healthy appearance, free from atrophy - moderate bilateral accumbens atrophy - caudate appears structurally intact with no atrophic changes - the thalamus shows no structural abnormalities indicative of atrophy - mild left atrophy of the pallidum
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ADNI_013_S_5071_MR_MPRAGE_br_raw_20130215130506824_28_S182443_I360324
On a T1-weighted brain MRI of a 77-year-old male subject, we observed: For the ventricles: - 4th ventricle is free from enlargement or excessive growth - 3rd ventricle is free from enlargement or excessive growth - no signs of enlargement detected in the lateral ventricle - the inf. lateral ventricle shows no structural abnormalities indicative of enlargement - no signs of enlargement detected in the external csf For the cerebral cortex: - insular cortex presents with a healthy appearance, free from atrophy - temporal lobe appears structurally intact with no atrophic changes - parietal lobe maintains its normal morphology without atrophic features - focal atrophy of occipital lobe on occipital pole (moderate) - focal atrophy of limbic cortex on parahippocampal gyrus (mild) - atrophies of frontal lobe on gyrus rectus (between normal and mild), medial orbital gyrus (mild) and posterior orbital gyrus (mild) For the subcortical structures: - no degenerative or atrophic changes noted in the putamen - basal forebrain maintains its normal morphology without atrophic features - no observable atrophic alterations in the thalamus - caudate appears structurally intact with no atrophic changes - no evidence of atrophy or degeneration in the accumbens - the hippocampus shows no structural abnormalities indicative of atrophy - pallidum appears structurally intact with no atrophic changes - mild atrophy of the amygdala, more pronounced on the left - ventral dc appears structurally intact with no atrophic changes
AD
ADNI_127_S_5067_MR_Accelerated_Sag_IR-FSPGR_br_raw_20130204134411723_7_S181409_I357660
On a T1-weighted brain MRI of a 81-year-old male subject, we observed: For the subcortical structures: - basal forebrain maintains its normal morphology without atrophic features - no pathological changes consistent with atrophy detected in the putamen - severe bilateral amygdala atrophy - between mild and moderate bilateral pallidum atrophy - no observable atrophic alterations in the accumbens - no pathological changes consistent with atrophy detected in the thalamus - caudate presents with a healthy appearance, free from atrophy - moderate bilateral ventral dc atrophy - moderate bilateral hippocampus atrophy, more pronounced on the left For the ventricles: - no pathological changes consistent with enlargement noted in the lateral ventricle - no enlargement observed in the 4th ventricle - external csf appears structurally intact, with no evidence of enlargement - no abnormal enlargement observed in the 3rd ventricle - mild enlargement of the inf. lateral ventricle For the cerebral cortex: - no evidence of atrophy or degeneration in the occipital lobe - no observable atrophic alterations in the parietal lobe - no evidence of atrophy or degeneration in the insular cortex - atrophies of limbic cortex on entorhinal area (moderate) and parahippocampal gyrus (between moderate and severe) - no degenerative or atrophic changes noted in the frontal lobe - focal atrophy of temporal lobe on planum polare (mild)
AD
ADNI_098_S_4201_MR_Accelerated_Sag_IR-SPGR__br_raw_20110915152919253_90_S122171_I256181
On a T1-weighted brain MRI of a 64-year-old female subject, we observed: For the cerebral cortex: - focal atrophy of frontal lobe on sup. frontal gyrus medial segment (between normal and mild) - no evidence of atrophy or degeneration in the insular cortex - focal atrophy of occipital lobe on middle occipital gyrus (between normal and mild) - parietal lobe remains normal, with no signs of tissue loss - severe bilateral temporal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: middle temporal gyrus (severe) and sup. temporal gyrus (moderate) - no observable atrophic alterations in the limbic cortex For the ventricles: - no signs of enlargement detected in the 3rd ventricle - no observable enlargement or abnormal growth in the external csf - no pathological changes consistent with enlargement noted in the lateral ventricle - the 4th ventricle shows no structural abnormalities indicative of enlargement - inf. lateral ventricle maintains its normal volume without signs of enlargement For the subcortical structures: - basal forebrain presents with a healthy appearance, free from atrophy - ventral dc presents with a healthy appearance, free from atrophy - moderate atrophy of the amygdala, more pronounced on the right - no evidence of atrophy or degeneration in the pallidum - caudate presents with a healthy appearance, free from atrophy - between normal and mild right atrophy of the accumbens - no pathological changes consistent with atrophy detected in the hippocampus - no evidence of atrophy or degeneration in the putamen - thalamus presents with a healthy appearance, free from atrophy
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ADNI_099_S_4994_MR_MPRAGE_br_raw_20121203123842054_174_S176117_I348826
On a T1-weighted brain MRI of a 85-year-old male subject, we observed: For the cerebral cortex: - occipital lobe appears structurally intact with no atrophic changes - focal atrophy of frontal lobe on precentral gyrus medial segment (mild) - insular cortex presents with a healthy appearance, free from atrophy - mild atrophy of the parietal lobe, with focal volume loss observed in the following subregions: sup. parietal lobule (between mild and moderate) - the limbic cortex shows no structural abnormalities indicative of atrophy - moderate atrophy of the temporal lobe, more pronounced on the left, with focal volume loss observed in the following subregions: planum temporale (between normal and mild), inf. temporal gyrus (moderate) and temporal pole (moderate) For the ventricles: - no observable enlargement or abnormal growth in the 3rd ventricle - no observable enlargement or abnormal growth in the external csf - between moderate and severe left enlargement of the inf. lateral ventricle - no abnormal enlargement observed in the lateral ventricle - no abnormal enlargement observed in the 4th ventricle For the subcortical structures: - no pathological changes consistent with atrophy detected in the thalamus - basal forebrain maintains its normal morphology without atrophic features - no evidence of atrophy or degeneration in the ventral dc - between normal and mild left atrophy of the caudate - between normal and mild atrophy of the amygdala, more pronounced on the left - accumbens remains normal, with no signs of tissue loss - moderate left atrophy of the hippocampus - mild left atrophy of the putamen - pallidum presents with a healthy appearance, free from atrophy
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ADNI_123_S_4526_MR_MPRAGE_br_raw_20120209093528861_37_S140267_I283603
On a T1-weighted brain MRI of a 80-year-old male subject, we observed: For the ventricles: - no observable enlargement or abnormal growth in the 4th ventricle - no signs of enlargement detected in the external csf - the inf. lateral ventricle shows no structural abnormalities indicative of enlargement - no abnormal enlargement observed in the 3rd ventricle - no enlargement observed in the lateral ventricle For the cerebral cortex: - no pathological changes consistent with atrophy detected in the limbic cortex - no signs of atrophy detected in the temporal lobe - the occipital lobe shows no structural abnormalities indicative of atrophy - insular cortex appears structurally intact with no atrophic changes - parietal lobe remains normal, with no signs of tissue loss - frontal lobe presents with a healthy appearance, free from atrophy For the subcortical structures: - between moderate and severe bilateral amygdala atrophy, more pronounced on the left - no observable atrophic alterations in the accumbens - pallidum presents with a healthy appearance, free from atrophy - no signs of atrophy detected in the caudate - no observable atrophic alterations in the thalamus - the putamen shows no structural abnormalities indicative of atrophy - basal forebrain presents with a healthy appearance, free from atrophy - no pathological changes consistent with atrophy detected in the ventral dc - between normal and mild atrophy of the hippocampus, more pronounced on the left
AD
ADNI_136_S_4993_MR_MPRAGE_br_raw_20121025150812723_51_S172271_I342522
On a T1-weighted brain MRI of a 72-year-old female subject, we observed: For the subcortical structures: - hippocampus presents with a healthy appearance, free from atrophy - the putamen shows no structural abnormalities indicative of atrophy - between normal and mild left atrophy of the basal forebrain - no evidence of atrophy or degeneration in the pallidum - no evidence of atrophy or degeneration in the accumbens - ventral dc appears structurally intact with no atrophic changes - amygdala maintains its normal morphology without atrophic features - no signs of atrophy detected in the caudate - thalamus maintains its normal morphology without atrophic features For the cerebral cortex: - no pathological changes consistent with atrophy detected in the temporal lobe - focal atrophy of frontal lobe on gyrus rectus (between normal and mild) - insular cortex appears structurally intact with no atrophic changes - no evidence of atrophy or degeneration in the parietal lobe - the limbic cortex shows no structural abnormalities indicative of atrophy - no observable atrophic alterations in the occipital lobe For the ventricles: - external csf is free from enlargement or excessive growth - 3rd ventricle appears structurally intact, with no evidence of enlargement - moderate enlargement of the inf. lateral ventricle, more pronounced on the left - no enlargement observed in the lateral ventricle - 4th ventricle remains within normal size parameters, with no enlargement detected
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ADNI_135_S_4954_MR_MPRAGE_br_raw_20120924115236764_47_S168533_I336502
On a T1-weighted brain MRI of a 62-year-old male subject, we observed: For the subcortical structures: - amygdala remains normal, with no signs of tissue loss - no evidence of atrophy or degeneration in the caudate - no observable atrophic alterations in the basal forebrain - the hippocampus shows no structural abnormalities indicative of atrophy - no degenerative or atrophic changes noted in the putamen - no pathological changes consistent with atrophy detected in the accumbens - no pathological changes consistent with atrophy detected in the ventral dc - the pallidum shows no structural abnormalities indicative of atrophy - mild bilateral thalamus atrophy For the ventricles: - the inf. lateral ventricle shows no structural abnormalities indicative of enlargement - the 3rd ventricle shows no structural abnormalities indicative of enlargement - lateral ventricle remains within normal size parameters, with no enlargement detected - the 4th ventricle shows no structural abnormalities indicative of enlargement - external csf is free from enlargement or excessive growth For the cerebral cortex: - no pathological changes consistent with atrophy detected in the insular cortex - no pathological changes consistent with atrophy detected in the frontal lobe - no evidence of atrophy or degeneration in the parietal lobe - occipital lobe presents with a healthy appearance, free from atrophy - limbic cortex presents with a healthy appearance, free from atrophy - temporal lobe presents with a healthy appearance, free from atrophy
AD
ADNI_016_S_4583_MR_Accelerated_SAG_IR-SPGR__br_raw_20120329134055367_164_S145153_I294212
On a T1-weighted brain MRI of a 87-year-old male subject, we observed: For the cerebral cortex: - focal atrophy of frontal lobe on sup. frontal gyrus medial segment (between moderate and severe) - occipital lobe remains normal, with no signs of tissue loss - moderate bilateral temporal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: inf. temporal gyrus (severe) and transverse temporal gyrus (mild) - severe bilateral parietal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: precuneus (moderate) and supramarginal gyrus (moderate) - mild atrophy of the insular cortex, with focal volume loss observed in the following subregions: anterior insula (between normal and mild) - limbic cortex presents with a healthy appearance, free from atrophy For the subcortical structures: - no degenerative or atrophic changes noted in the putamen - no signs of atrophy detected in the basal forebrain - no signs of atrophy detected in the caudate - no evidence of atrophy or degeneration in the hippocampus - no evidence of atrophy or degeneration in the ventral dc - no degenerative or atrophic changes noted in the accumbens - thalamus appears structurally intact with no atrophic changes - between normal and mild atrophy of the amygdala, more pronounced on the right - pallidum presents with a healthy appearance, free from atrophy For the ventricles: - between normal and mild enlargement of the external csf - the 3rd ventricle shows no structural abnormalities indicative of enlargement - no observable enlargement or abnormal growth in the inf. lateral ventricle - no abnormal enlargement observed in the lateral ventricle - no observable enlargement or abnormal growth in the 4th ventricle
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ADNI_018_S_5240_MR_MPRAGE_br_raw_20130723160412209_118_S196225_I382181
On a T1-weighted brain MRI of a 63-year-old female subject, we observed: For the cerebral cortex: - limbic cortex maintains its normal morphology without atrophic features - no signs of atrophy detected in the parietal lobe - no observable atrophic alterations in the occipital lobe - focal atrophy of insular cortex on frontal operculum (moderate) - no evidence of atrophy or degeneration in the frontal lobe - no signs of atrophy detected in the temporal lobe For the ventricles: - lateral ventricle maintains its normal volume without signs of enlargement - 4th ventricle is free from enlargement or excessive growth - no enlargement observed in the external csf - 3rd ventricle is free from enlargement or excessive growth - no pathological changes consistent with enlargement noted in the inf. lateral ventricle For the subcortical structures: - the basal forebrain shows no structural abnormalities indicative of atrophy - no signs of atrophy detected in the ventral dc - no pathological changes consistent with atrophy detected in the pallidum - no pathological changes consistent with atrophy detected in the caudate - no signs of atrophy detected in the hippocampus - no evidence of atrophy or degeneration in the accumbens - the putamen shows no structural abnormalities indicative of atrophy - no pathological changes consistent with atrophy detected in the thalamus - no degenerative or atrophic changes noted in the amygdala
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ADNI_037_S_4770_MR_MPRAGE_br_raw_20120709115645978_143_S156967_I315489
On a T1-weighted brain MRI of a 76-year-old male subject, we observed: For the subcortical structures: - mild left atrophy of the thalamus - caudate maintains its normal morphology without atrophic features - severe bilateral amygdala atrophy - no evidence of atrophy or degeneration in the basal forebrain - between mild and moderate bilateral accumbens atrophy - putamen appears structurally intact with no atrophic changes - pallidum presents with a healthy appearance, free from atrophy - no evidence of atrophy or degeneration in the ventral dc - hippocampus presents with a healthy appearance, free from atrophy For the cerebral cortex: - between normal and mild atrophy of the frontal lobe, with focal volume loss observed in the following subregions: gyrus rectus (moderate) and posterior orbital gyrus (between normal and mild) - no signs of atrophy detected in the parietal lobe - moderate atrophy of the limbic cortex, with focal volume loss observed in the following subregions: middle cingulate gyrus (mild) and parahippocampal gyrus (mild) - occipital lobe appears structurally intact with no atrophic changes - focal atrophy of temporal lobe on planum temporale (mild) - mild atrophy of the insular cortex, with focal volume loss observed in the following subregions: anterior insula (mild) For the ventricles: - severe bilateral inf. lateral ventricle enlargement - no observable enlargement or abnormal growth in the lateral ventricle - mild enlargement of the external csf - no observable enlargement or abnormal growth in the 3rd ventricle - no abnormal enlargement observed in the 4th ventricle
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ADNI_003_S_4892_MR_Accelerated_SAG_IR-SPGR__br_raw_20120827170017619_71_S162721_I326457
On a T1-weighted brain MRI of a 75-year-old female subject, we observed: For the cerebral cortex: - no observable atrophic alterations in the frontal lobe - no signs of atrophy detected in the insular cortex - occipital lobe remains normal, with no signs of tissue loss - temporal lobe remains normal, with no signs of tissue loss - focal atrophy of parietal lobe on angular gyrus (mild) - no degenerative or atrophic changes noted in the limbic cortex For the subcortical structures: - accumbens appears structurally intact with no atrophic changes - amygdala maintains its normal morphology without atrophic features - the pallidum shows no structural abnormalities indicative of atrophy - between normal and mild atrophy of the basal forebrain, more pronounced on the right - no pathological changes consistent with atrophy detected in the thalamus - no observable atrophic alterations in the ventral dc - caudate appears structurally intact with no atrophic changes - no observable atrophic alterations in the putamen - hippocampus appears structurally intact with no atrophic changes For the ventricles: - no abnormal enlargement observed in the 4th ventricle - no enlargement observed in the lateral ventricle - no observable enlargement or abnormal growth in the inf. lateral ventricle - 3rd ventricle remains within normal size parameters, with no enlargement detected - no enlargement observed in the external csf
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ADNI_009_S_5224_MR_MPRAGE_br_raw_20130717152112089_161_S195460_I381184
On a T1-weighted brain MRI of a 79-year-old male subject, we observed: For the subcortical structures: - no pathological changes consistent with atrophy detected in the accumbens - mild atrophy of the hippocampus - no evidence of atrophy or degeneration in the basal forebrain - caudate remains normal, with no signs of tissue loss - pallidum presents with a healthy appearance, free from atrophy - between normal and mild right atrophy of the ventral dc - severe bilateral amygdala atrophy, more pronounced on the right - no observable atrophic alterations in the putamen - thalamus appears structurally intact with no atrophic changes For the ventricles: - no pathological changes consistent with enlargement noted in the external csf - no signs of enlargement detected in the 3rd ventricle - 4th ventricle maintains its normal volume without signs of enlargement - between normal and mild enlargement of the inf. lateral ventricle - the lateral ventricle shows no structural abnormalities indicative of enlargement For the cerebral cortex: - between mild and moderate atrophy of the temporal lobe, more pronounced on the right, with focal volume loss observed in the following subregions: middle temporal gyrus (between mild and moderate) and temporal pole (between moderate and severe) - between normal and mild atrophy of the insular cortex, more pronounced on the right - between mild and moderate atrophy of the limbic cortex, with focal volume loss observed in the following subregions: entorhinal area (severe) and parahippocampal gyrus (moderate) - parietal lobe maintains its normal morphology without atrophic features - no signs of atrophy detected in the frontal lobe - focal atrophy of occipital lobe on inf. occipital gyrus (mild)
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ADNI_135_S_4657_MR_MPRAGE_br_raw_20120412141545566_116_S147060_I297169
On a T1-weighted brain MRI of a 72-year-old female subject, we observed: For the ventricles: - no observable enlargement or abnormal growth in the inf. lateral ventricle - between mild and moderate enlargement of the 3rd ventricle - no pathological changes consistent with enlargement noted in the external csf - no enlargement observed in the lateral ventricle - the 4th ventricle shows no structural abnormalities indicative of enlargement For the subcortical structures: - thalamus maintains its normal morphology without atrophic features - moderate bilateral hippocampus atrophy - basal forebrain presents with a healthy appearance, free from atrophy - putamen presents with a healthy appearance, free from atrophy - ventral dc appears structurally intact with no atrophic changes - between moderate and severe bilateral amygdala atrophy - no evidence of atrophy or degeneration in the caudate - the pallidum shows no structural abnormalities indicative of atrophy - accumbens appears structurally intact with no atrophic changes For the cerebral cortex: - mild atrophy of the parietal lobe, with focal volume loss observed in the following subregions: angular gyrus (between mild and moderate) - frontal lobe presents with a healthy appearance, free from atrophy - atrophies of occipital lobe on middle occipital gyrus (moderate) and occipital fusiform gyrus (between normal and mild) - severe bilateral temporal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: fusiform gyrus (moderate), inf. temporal gyrus (between moderate and severe), middle temporal gyrus (severe) and temporal pole (moderate) - no signs of atrophy detected in the insular cortex - focal atrophy of limbic cortex on entorhinal area (moderate)
AD
ADNI_011_S_4906_MR_MPRAGE_br_raw_20120904143307512_81_S165942_I330056
On a T1-weighted brain MRI of a 76-year-old female subject, we observed: For the ventricles: - no observable enlargement or abnormal growth in the 3rd ventricle - no pathological changes consistent with enlargement noted in the 4th ventricle - between normal and mild enlargement of the inf. lateral ventricle, more pronounced on the left - no observable enlargement or abnormal growth in the lateral ventricle - no pathological changes consistent with enlargement noted in the external csf For the cerebral cortex: - focal atrophy of temporal lobe on sup. temporal gyrus (between mild and moderate) - the frontal lobe shows no structural abnormalities indicative of atrophy - occipital lobe appears structurally intact with no atrophic changes - insular cortex maintains its normal morphology without atrophic features - parietal lobe remains normal, with no signs of tissue loss - the limbic cortex shows no structural abnormalities indicative of atrophy For the subcortical structures: - basal forebrain remains normal, with no signs of tissue loss - the thalamus shows no structural abnormalities indicative of atrophy - between normal and mild right atrophy of the ventral dc - the accumbens shows no structural abnormalities indicative of atrophy - amygdala appears structurally intact with no atrophic changes - no observable atrophic alterations in the caudate - putamen presents with a healthy appearance, free from atrophy - between normal and mild atrophy of the hippocampus, more pronounced on the left - the pallidum shows no structural abnormalities indicative of atrophy
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ADNI_021_S_4718_MR_Accelerated_Sag_IR-SPGR__br_raw_20120516162344538_10_S150673_I304759
On a T1-weighted brain MRI of a 79-year-old male subject, we observed: For the ventricles: - lateral ventricle is free from enlargement or excessive growth - no observable enlargement or abnormal growth in the 3rd ventricle - 4th ventricle maintains its normal volume without signs of enlargement - severe bilateral inf. lateral ventricle enlargement, more pronounced on the right - external csf remains within normal size parameters, with no enlargement detected For the subcortical structures: - no observable atrophic alterations in the ventral dc - pallidum maintains its normal morphology without atrophic features - putamen appears structurally intact with no atrophic changes - mild right atrophy of the thalamus - no pathological changes consistent with atrophy detected in the basal forebrain - severe bilateral amygdala atrophy - accumbens appears structurally intact with no atrophic changes - no pathological changes consistent with atrophy detected in the caudate - mild right atrophy of the hippocampus For the cerebral cortex: - no observable atrophic alterations in the insular cortex - focal atrophy of limbic cortex on anterior cingulate gyrus (between normal and mild) - occipital lobe appears structurally intact with no atrophic changes - severe bilateral parietal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: angular gyrus (moderate), postcentral gyrus (mild) and precuneus (between normal and mild) - moderate atrophy of the temporal lobe, more pronounced on the right, with focal volume loss observed in the following subregions: fusiform gyrus (between mild and moderate), inf. temporal gyrus (mild) and middle temporal gyrus (moderate) - focal atrophy of frontal lobe on medial frontal cortex (mild)
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ADNI_019_S_4477_MR_MPRAGE_br_raw_20120126085251352_103_S138533_I280783
On a T1-weighted brain MRI of a 83-year-old female subject, we observed: For the cerebral cortex: - focal atrophy of occipital lobe on occipital fusiform gyrus (between normal and mild) - no observable atrophic alterations in the parietal lobe - atrophies of frontal lobe on opercular inf. frontal gyrus (between normal and mild) and medial frontal cortex (between normal and mild) - insular cortex maintains its normal morphology without atrophic features - between normal and mild atrophy of the limbic cortex, with focal volume loss observed in the following subregions: anterior cingulate gyrus (between normal and mild) - focal atrophy of temporal lobe on middle temporal gyrus (moderate) For the subcortical structures: - moderate bilateral hippocampus atrophy - no degenerative or atrophic changes noted in the basal forebrain - no signs of atrophy detected in the thalamus - moderate bilateral amygdala atrophy - no signs of atrophy detected in the putamen - caudate maintains its normal morphology without atrophic features - no pathological changes consistent with atrophy detected in the pallidum - ventral dc presents with a healthy appearance, free from atrophy - between mild and moderate atrophy of the accumbens, more pronounced on the right For the ventricles: - 3rd ventricle remains within normal size parameters, with no enlargement detected - no observable enlargement or abnormal growth in the 4th ventricle - inf. lateral ventricle remains within normal size parameters, with no enlargement detected - no signs of enlargement detected in the lateral ventricle - mild enlargement of the external csf
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ADNI_052_S_5062_MR_Accelerated_Sag_IR-FSPGR_br_raw_20130128154823597_111_S181117_I356514
On a T1-weighted brain MRI of a 71-year-old female subject, we observed: For the cerebral cortex: - the limbic cortex shows no structural abnormalities indicative of atrophy - parietal lobe maintains its normal morphology without atrophic features - atrophies of temporal lobe on planum temporale (between normal and mild) and sup. temporal gyrus (between moderate and severe) - the occipital lobe shows no structural abnormalities indicative of atrophy - no degenerative or atrophic changes noted in the frontal lobe - the insular cortex shows no structural abnormalities indicative of atrophy For the subcortical structures: - caudate remains normal, with no signs of tissue loss - ventral dc maintains its normal morphology without atrophic features - pallidum presents with a healthy appearance, free from atrophy - no observable atrophic alterations in the putamen - basal forebrain maintains its normal morphology without atrophic features - accumbens appears structurally intact with no atrophic changes - thalamus remains normal, with no signs of tissue loss - no evidence of atrophy or degeneration in the amygdala - hippocampus remains normal, with no signs of tissue loss For the ventricles: - lateral ventricle appears structurally intact, with no evidence of enlargement - mild left enlargement of the inf. lateral ventricle - 4th ventricle is free from enlargement or excessive growth - no enlargement observed in the external csf - no enlargement observed in the 3rd ventricle
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ADNI_067_S_4728_MR_MPRAGE_br_raw_20120601105317930_38_S152456_I307594
On a T1-weighted brain MRI of a 82-year-old male subject, we observed: For the ventricles: - no signs of enlargement detected in the external csf - severe enlargement of the inf. lateral ventricle, more pronounced on the right - mild enlargement of the 3rd ventricle - moderate bilateral lateral ventricle enlargement - no enlargement observed in the 4th ventricle For the subcortical structures: - between moderate and severe atrophy of the amygdala, more pronounced on the right - pallidum maintains its normal morphology without atrophic features - no degenerative or atrophic changes noted in the putamen - no signs of atrophy detected in the basal forebrain - no observable atrophic alterations in the thalamus - no degenerative or atrophic changes noted in the hippocampus - moderate bilateral accumbens atrophy - no pathological changes consistent with atrophy detected in the ventral dc - caudate appears structurally intact with no atrophic changes For the cerebral cortex: - focal atrophy of parietal lobe on sup. parietal lobule (moderate) - no evidence of atrophy or degeneration in the insular cortex - no signs of atrophy detected in the limbic cortex - severe bilateral temporal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: fusiform gyrus (moderate), inf. temporal gyrus (between moderate and severe) and temporal pole (moderate) - no evidence of atrophy or degeneration in the occipital lobe - focal atrophy of frontal lobe on middle frontal gyrus (between normal and mild)
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ADNI_036_S_4820_MR_MPRAGE_br_raw_20120718104734388_6_S157909_I316737
On a T1-weighted brain MRI of a 86-year-old female subject, we observed: For the subcortical structures: - the thalamus shows no structural abnormalities indicative of atrophy - no degenerative or atrophic changes noted in the putamen - no signs of atrophy detected in the caudate - between normal and mild atrophy of the accumbens - no degenerative or atrophic changes noted in the hippocampus - no evidence of atrophy or degeneration in the pallidum - basal forebrain appears structurally intact with no atrophic changes - ventral dc maintains its normal morphology without atrophic features - no observable atrophic alterations in the amygdala For the cerebral cortex: - severe bilateral occipital lobe atrophy, with focal volume loss observed in the following subregions: inf. occipital gyrus (between normal and mild) - no degenerative or atrophic changes noted in the insular cortex - focal atrophy of limbic cortex on anterior cingulate gyrus (between normal and mild) - no degenerative or atrophic changes noted in the parietal lobe - focal atrophy of temporal lobe on inf. temporal gyrus (between normal and mild) - no signs of atrophy detected in the frontal lobe For the ventricles: - the 4th ventricle shows no structural abnormalities indicative of enlargement - no observable enlargement or abnormal growth in the 3rd ventricle - inf. lateral ventricle is free from enlargement or excessive growth - external csf remains within normal size parameters, with no enlargement detected - lateral ventricle appears structurally intact, with no evidence of enlargement
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ADNI_014_S_4615_MR_MPRAGE_br_raw_20120330084522944_163_S145232_I294334
On a T1-weighted brain MRI of a 87-year-old male subject, we observed: For the subcortical structures: - putamen appears structurally intact with no atrophic changes - no degenerative or atrophic changes noted in the accumbens - caudate appears structurally intact with no atrophic changes - between normal and mild atrophy of the basal forebrain, more pronounced on the left - thalamus appears structurally intact with no atrophic changes - mild atrophy of the hippocampus, more pronounced on the left - no evidence of atrophy or degeneration in the pallidum - no signs of atrophy detected in the ventral dc - moderate bilateral amygdala atrophy, more pronounced on the left For the ventricles: - between normal and mild enlargement of the inf. lateral ventricle - no enlargement observed in the 4th ventricle - no observable enlargement or abnormal growth in the lateral ventricle - no signs of enlargement detected in the external csf - no abnormal enlargement observed in the 3rd ventricle For the cerebral cortex: - the frontal lobe shows no structural abnormalities indicative of atrophy - no pathological changes consistent with atrophy detected in the limbic cortex - no degenerative or atrophic changes noted in the occipital lobe - parietal lobe presents with a healthy appearance, free from atrophy - no pathological changes consistent with atrophy detected in the insular cortex - focal atrophy of temporal lobe on temporal pole (between normal and mild)
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ADNI_003_S_5187_MR_Accelerated_SAG_IR-SPGR__br_raw_20130610202342271_157_S191910_I375951
On a T1-weighted brain MRI of a 62-year-old female subject, we observed: For the subcortical structures: - putamen maintains its normal morphology without atrophic features - severe bilateral amygdala atrophy - no observable atrophic alterations in the pallidum - caudate remains normal, with no signs of tissue loss - no observable atrophic alterations in the basal forebrain - severe bilateral hippocampus atrophy - thalamus maintains its normal morphology without atrophic features - accumbens appears structurally intact with no atrophic changes - no evidence of atrophy or degeneration in the ventral dc For the ventricles: - inf. lateral ventricle maintains its normal volume without signs of enlargement - 3rd ventricle remains within normal size parameters, with no enlargement detected - mild right enlargement of the lateral ventricle - external csf is free from enlargement or excessive growth - 4th ventricle appears structurally intact, with no evidence of enlargement For the cerebral cortex: - frontal lobe maintains its normal morphology without atrophic features - atrophies of parietal lobe on precuneus (between normal and mild) and sup. parietal lobule (between normal and mild) - atrophies of occipital lobe on calcarine cortex (between normal and mild), occipital fusiform gyrus (between normal and mild), sup. occipital gyrus (between normal and mild) and occipital pole (between mild and moderate) - no evidence of atrophy or degeneration in the insular cortex - limbic cortex remains normal, with no signs of tissue loss - focal atrophy of temporal lobe on planum temporale (mild)
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ADNI_131_S_5138_MR_MPRAGE_br_raw_20130417113829938_29_S187196_I367565
On a T1-weighted brain MRI of a 61-year-old male subject, we observed: For the cerebral cortex: - insular cortex maintains its normal morphology without atrophic features - no degenerative or atrophic changes noted in the occipital lobe - focal atrophy of frontal lobe on medial orbital gyrus (between normal and mild) - no signs of atrophy detected in the limbic cortex - focal atrophy of parietal lobe on sup. parietal lobule (mild) - no pathological changes consistent with atrophy detected in the temporal lobe For the subcortical structures: - accumbens presents with a healthy appearance, free from atrophy - putamen presents with a healthy appearance, free from atrophy - no pathological changes consistent with atrophy detected in the thalamus - no evidence of atrophy or degeneration in the basal forebrain - no degenerative or atrophic changes noted in the amygdala - ventral dc presents with a healthy appearance, free from atrophy - no pathological changes consistent with atrophy detected in the caudate - pallidum appears structurally intact with no atrophic changes - the hippocampus shows no structural abnormalities indicative of atrophy For the ventricles: - 3rd ventricle maintains its normal volume without signs of enlargement - 4th ventricle maintains its normal volume without signs of enlargement - the inf. lateral ventricle shows no structural abnormalities indicative of enlargement - external csf is free from enlargement or excessive growth - no abnormal enlargement observed in the lateral ventricle
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ADNI_126_S_4494_MR_Accelerated_Sag_IR-SPGR__br_raw_20120131123025629_91_S138966_I281601
On a T1-weighted brain MRI of a 71-year-old male subject, we observed: For the subcortical structures: - between mild and moderate bilateral hippocampus atrophy - thalamus remains normal, with no signs of tissue loss - no signs of atrophy detected in the pallidum - no evidence of atrophy or degeneration in the caudate - severe bilateral amygdala atrophy - putamen presents with a healthy appearance, free from atrophy - basal forebrain presents with a healthy appearance, free from atrophy - no pathological changes consistent with atrophy detected in the ventral dc - no evidence of atrophy or degeneration in the accumbens For the cerebral cortex: - insular cortex presents with a healthy appearance, free from atrophy - no evidence of atrophy or degeneration in the temporal lobe - frontal lobe appears structurally intact with no atrophic changes - focal atrophy of limbic cortex on entorhinal area (between mild and moderate) - no degenerative or atrophic changes noted in the parietal lobe - no evidence of atrophy or degeneration in the occipital lobe For the ventricles: - mild right enlargement of the inf. lateral ventricle - the external csf shows no structural abnormalities indicative of enlargement - 4th ventricle is free from enlargement or excessive growth - 3rd ventricle maintains its normal volume without signs of enlargement - no enlargement observed in the lateral ventricle
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ADNI_007_S_5196_MR_Accelerated_SAG_IR-SPGR__br_raw_20130612130338802_16_S192134_I376238
On a T1-weighted brain MRI of a 73-year-old female subject, we observed: For the subcortical structures: - caudate maintains its normal morphology without atrophic features - putamen remains normal, with no signs of tissue loss - no evidence of atrophy or degeneration in the thalamus - pallidum presents with a healthy appearance, free from atrophy - between normal and mild atrophy of the ventral dc - no observable atrophic alterations in the accumbens - severe bilateral amygdala atrophy - basal forebrain maintains its normal morphology without atrophic features - moderate bilateral hippocampus atrophy For the cerebral cortex: - no signs of atrophy detected in the parietal lobe - no pathological changes consistent with atrophy detected in the occipital lobe - no evidence of atrophy or degeneration in the temporal lobe - frontal lobe maintains its normal morphology without atrophic features - limbic cortex remains normal, with no signs of tissue loss - insular cortex presents with a healthy appearance, free from atrophy For the ventricles: - external csf is free from enlargement or excessive growth - no signs of enlargement detected in the lateral ventricle - 3rd ventricle remains within normal size parameters, with no enlargement detected - no abnormal enlargement observed in the inf. lateral ventricle - 4th ventricle is free from enlargement or excessive growth
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ADNI_011_S_4827_MR_MPRAGE_br_raw_20120703085506250_153_S156389_I314042
On a T1-weighted brain MRI of a 72-year-old male subject, we observed: For the subcortical structures: - caudate presents with a healthy appearance, free from atrophy - between normal and mild left atrophy of the thalamus - no pathological changes consistent with atrophy detected in the hippocampus - moderate atrophy of the amygdala, more pronounced on the left - no evidence of atrophy or degeneration in the ventral dc - no pathological changes consistent with atrophy detected in the basal forebrain - pallidum maintains its normal morphology without atrophic features - accumbens maintains its normal morphology without atrophic features - between normal and mild left atrophy of the putamen For the ventricles: - no observable enlargement or abnormal growth in the inf. lateral ventricle - 4th ventricle appears structurally intact, with no evidence of enlargement - no enlargement observed in the lateral ventricle - severe enlargement of the external csf - no abnormal enlargement observed in the 3rd ventricle For the cerebral cortex: - focal atrophy of parietal lobe on postcentral gyrus medial segment (moderate) - limbic cortex appears structurally intact with no atrophic changes - no pathological changes consistent with atrophy detected in the insular cortex - between normal and mild atrophy of the frontal lobe, with focal volume loss observed in the following subregions: opercular inf. frontal gyrus (between normal and mild) - no pathological changes consistent with atrophy detected in the occipital lobe - temporal lobe appears structurally intact with no atrophic changes
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ADNI_099_S_4124_MR_MPRAGE_br_raw_20110728114051898_41_S116633_I247513
On a T1-weighted brain MRI of a 73-year-old male subject, we observed: For the subcortical structures: - the thalamus shows no structural abnormalities indicative of atrophy - between mild and moderate bilateral amygdala atrophy - pallidum presents with a healthy appearance, free from atrophy - no signs of atrophy detected in the putamen - no signs of atrophy detected in the accumbens - severe bilateral hippocampus atrophy, more pronounced on the left - the basal forebrain shows no structural abnormalities indicative of atrophy - ventral dc presents with a healthy appearance, free from atrophy - no pathological changes consistent with atrophy detected in the caudate For the cerebral cortex: - the frontal lobe shows no structural abnormalities indicative of atrophy - between normal and mild atrophy of the limbic cortex - temporal lobe maintains its normal morphology without atrophic features - no degenerative or atrophic changes noted in the parietal lobe - occipital lobe appears structurally intact with no atrophic changes - no degenerative or atrophic changes noted in the insular cortex For the ventricles: - no signs of enlargement detected in the external csf - the 3rd ventricle shows no structural abnormalities indicative of enlargement - inf. lateral ventricle appears structurally intact, with no evidence of enlargement - lateral ventricle appears structurally intact, with no evidence of enlargement - no signs of enlargement detected in the 4th ventricle
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ADNI_016_S_5057_MR_Accelerated_SAG_IR-SPGR__br_raw_20130226082518326_195_S183095_I361230
On a T1-weighted brain MRI of a 75-year-old male subject, we observed: For the subcortical structures: - no degenerative or atrophic changes noted in the thalamus - ventral dc presents with a healthy appearance, free from atrophy - no signs of atrophy detected in the pallidum - caudate maintains its normal morphology without atrophic features - amygdala remains normal, with no signs of tissue loss - the basal forebrain shows no structural abnormalities indicative of atrophy - no signs of atrophy detected in the putamen - hippocampus appears structurally intact with no atrophic changes - no degenerative or atrophic changes noted in the accumbens For the ventricles: - external csf maintains its normal volume without signs of enlargement - 3rd ventricle remains within normal size parameters, with no enlargement detected - severe bilateral inf. lateral ventricle enlargement - lateral ventricle maintains its normal volume without signs of enlargement - no abnormal enlargement observed in the 4th ventricle For the cerebral cortex: - frontal lobe presents with a healthy appearance, free from atrophy - no evidence of atrophy or degeneration in the occipital lobe - focal atrophy of limbic cortex on entorhinal area (between normal and mild) - the parietal lobe shows no structural abnormalities indicative of atrophy - insular cortex appears structurally intact with no atrophic changes - no evidence of atrophy or degeneration in the temporal lobe
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ADNI_010_S_5163_MR_MPRAGE_br_raw_20130606120905404_67_S191475_I375336
On a T1-weighted brain MRI of a 67-year-old male subject, we observed: For the subcortical structures: - pallidum presents with a healthy appearance, free from atrophy - no observable atrophic alterations in the ventral dc - basal forebrain remains normal, with no signs of tissue loss - between normal and mild atrophy of the amygdala - accumbens appears structurally intact with no atrophic changes - caudate maintains its normal morphology without atrophic features - thalamus appears structurally intact with no atrophic changes - no signs of atrophy detected in the hippocampus - putamen remains normal, with no signs of tissue loss For the cerebral cortex: - the limbic cortex shows no structural abnormalities indicative of atrophy - no signs of atrophy detected in the parietal lobe - occipital lobe maintains its normal morphology without atrophic features - moderate bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: gyrus rectus (between mild and moderate), opercular inf. frontal gyrus (between mild and moderate), middle frontal gyrus (moderate) and medial orbital gyrus (moderate) - focal atrophy of temporal lobe on inf. temporal gyrus (mild) - no pathological changes consistent with atrophy detected in the insular cortex For the ventricles: - no signs of enlargement detected in the lateral ventricle - between mild and moderate enlargement of the external csf - 3rd ventricle appears structurally intact, with no evidence of enlargement - 4th ventricle maintains its normal volume without signs of enlargement - no pathological changes consistent with enlargement noted in the inf. lateral ventricle
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ADNI_135_S_4676_MR_MPRAGE_br_raw_20120419112023754_126_S147672_I298456
On a T1-weighted brain MRI of a 79-year-old male subject, we observed: For the subcortical structures: - thalamus remains normal, with no signs of tissue loss - no signs of atrophy detected in the basal forebrain - putamen presents with a healthy appearance, free from atrophy - between normal and mild right atrophy of the pallidum - no degenerative or atrophic changes noted in the accumbens - ventral dc maintains its normal morphology without atrophic features - amygdala maintains its normal morphology without atrophic features - caudate presents with a healthy appearance, free from atrophy - between mild and moderate atrophy of the hippocampus, more pronounced on the right For the cerebral cortex: - no evidence of atrophy or degeneration in the parietal lobe - occipital lobe appears structurally intact with no atrophic changes - the frontal lobe shows no structural abnormalities indicative of atrophy - no pathological changes consistent with atrophy detected in the temporal lobe - focal atrophy of limbic cortex on entorhinal area (between normal and mild) - focal atrophy of insular cortex on anterior insula (between normal and mild) For the ventricles: - lateral ventricle remains within normal size parameters, with no enlargement detected - 3rd ventricle remains within normal size parameters, with no enlargement detected - no pathological changes consistent with enlargement noted in the 4th ventricle - no observable enlargement or abnormal growth in the inf. lateral ventricle - external csf remains within normal size parameters, with no enlargement detected
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ADNI_135_S_5275_MR_MPRAGE_br_raw_20130805125009417_8_S197268_I384344
On a T1-weighted brain MRI of a 78-year-old female subject, we observed: For the cerebral cortex: - focal atrophy of temporal lobe on planum polare (mild) - focal atrophy of frontal lobe on sup. frontal gyrus medial segment (between normal and mild) - no evidence of atrophy or degeneration in the limbic cortex - parietal lobe presents with a healthy appearance, free from atrophy - atrophies of occipital lobe on cuneus (between mild and moderate) and occipital fusiform gyrus (between normal and mild) - no pathological changes consistent with atrophy detected in the insular cortex For the subcortical structures: - no observable atrophic alterations in the thalamus - accumbens presents with a healthy appearance, free from atrophy - between mild and moderate bilateral pallidum atrophy - basal forebrain remains normal, with no signs of tissue loss - no pathological changes consistent with atrophy detected in the amygdala - no degenerative or atrophic changes noted in the hippocampus - moderate bilateral putamen atrophy - between normal and mild atrophy of the caudate - between mild and moderate bilateral ventral dc atrophy For the ventricles: - no enlargement observed in the inf. lateral ventricle - 4th ventricle appears structurally intact, with no evidence of enlargement - no abnormal enlargement observed in the external csf - the 3rd ventricle shows no structural abnormalities indicative of enlargement - between normal and mild right enlargement of the lateral ventricle
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ADNI_135_S_4863_MR_MPRAGE_br_raw_20120801122802329_55_S159175_I320487
On a T1-weighted brain MRI of a 71-year-old male subject, we observed: For the subcortical structures: - no evidence of atrophy or degeneration in the ventral dc - no evidence of atrophy or degeneration in the pallidum - hippocampus appears structurally intact with no atrophic changes - no pathological changes consistent with atrophy detected in the basal forebrain - no degenerative or atrophic changes noted in the putamen - severe bilateral amygdala atrophy, more pronounced on the left - no signs of atrophy detected in the thalamus - the accumbens shows no structural abnormalities indicative of atrophy - no pathological changes consistent with atrophy detected in the caudate For the cerebral cortex: - no pathological changes consistent with atrophy detected in the frontal lobe - focal atrophy of parietal lobe on postcentral gyrus medial segment (between mild and moderate) - focal atrophy of limbic cortex on entorhinal area (moderate) - focal atrophy of temporal lobe on inf. temporal gyrus (between normal and mild) - no evidence of atrophy or degeneration in the insular cortex - focal atrophy of occipital lobe on lingual gyrus (moderate) For the ventricles: - no signs of enlargement detected in the 3rd ventricle - lateral ventricle appears structurally intact, with no evidence of enlargement - 4th ventricle remains within normal size parameters, with no enlargement detected - external csf is free from enlargement or excessive growth - no observable enlargement or abnormal growth in the inf. lateral ventricle
AD
ADNI_007_S_4568_MR_Accelerated_SAG_IR-SPGR__br_raw_20120301171636342_136_S142282_I287481
On a T1-weighted brain MRI of a 71-year-old female subject, we observed: For the ventricles: - 3rd ventricle maintains its normal volume without signs of enlargement - no enlargement observed in the external csf - 4th ventricle appears structurally intact, with no evidence of enlargement - inf. lateral ventricle remains within normal size parameters, with no enlargement detected - lateral ventricle maintains its normal volume without signs of enlargement For the cerebral cortex: - limbic cortex presents with a healthy appearance, free from atrophy - no degenerative or atrophic changes noted in the temporal lobe - frontal lobe maintains its normal morphology without atrophic features - no signs of atrophy detected in the insular cortex - focal atrophy of occipital lobe on occipital pole (mild) - mild atrophy of the parietal lobe, with focal volume loss observed in the following subregions: sup. parietal lobule (severe) For the subcortical structures: - between normal and mild atrophy of the pallidum - the basal forebrain shows no structural abnormalities indicative of atrophy - the putamen shows no structural abnormalities indicative of atrophy - mild left atrophy of the accumbens - no pathological changes consistent with atrophy detected in the hippocampus - between moderate and severe bilateral amygdala atrophy - no pathological changes consistent with atrophy detected in the caudate - thalamus maintains its normal morphology without atrophic features - mild bilateral ventral dc atrophy
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ADNI_014_S_4039_MR_MPRAGE_br_raw_20110603075656539_127_S110533_I238745
On a T1-weighted brain MRI of a 56-year-old male subject, we observed: For the cerebral cortex: - between moderate and severe bilateral temporal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: fusiform gyrus (mild), middle temporal gyrus (between mild and moderate) and sup. temporal gyrus (mild) - severe bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: angular gyrus (between mild and moderate) and precuneus (severe) - no pathological changes consistent with atrophy detected in the limbic cortex - focal atrophy of occipital lobe on occipital fusiform gyrus (moderate) - focal atrophy of insular cortex on central operculum (between moderate and severe) - focal atrophy of frontal lobe on anterior orbital gyrus (moderate) For the ventricles: - no abnormal enlargement observed in the 4th ventricle - moderate enlargement of the inf. lateral ventricle - the 3rd ventricle shows no structural abnormalities indicative of enlargement - between normal and mild right enlargement of the lateral ventricle - between moderate and severe enlargement of the external csf For the subcortical structures: - no pathological changes consistent with atrophy detected in the caudate - no observable atrophic alterations in the thalamus - basal forebrain maintains its normal morphology without atrophic features - moderate atrophy of the amygdala, more pronounced on the right - hippocampus maintains its normal morphology without atrophic features - putamen presents with a healthy appearance, free from atrophy - mild atrophy of the accumbens, more pronounced on the right - no observable atrophic alterations in the pallidum - no degenerative or atrophic changes noted in the ventral dc
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ADNI_011_S_4912_MR_MPRAGE_br_raw_20120823092531324_144_S162366_I325980
On a T1-weighted brain MRI of a 70-year-old female subject, we observed: For the subcortical structures: - no evidence of atrophy or degeneration in the ventral dc - no observable atrophic alterations in the basal forebrain - accumbens remains normal, with no signs of tissue loss - between normal and mild atrophy of the thalamus - no pathological changes consistent with atrophy detected in the pallidum - between normal and mild bilateral caudate atrophy - severe bilateral hippocampus atrophy, more pronounced on the left - putamen appears structurally intact with no atrophic changes - between normal and mild atrophy of the amygdala For the ventricles: - the external csf shows no structural abnormalities indicative of enlargement - no observable enlargement or abnormal growth in the 3rd ventricle - lateral ventricle remains within normal size parameters, with no enlargement detected - the inf. lateral ventricle shows no structural abnormalities indicative of enlargement - the 4th ventricle shows no structural abnormalities indicative of enlargement For the cerebral cortex: - focal atrophy of frontal lobe on orbital inf. frontal gyrus (between normal and mild) - no evidence of atrophy or degeneration in the temporal lobe - no pathological changes consistent with atrophy detected in the occipital lobe - focal atrophy of parietal lobe on supramarginal gyrus (between normal and mild) - focal atrophy of limbic cortex on parahippocampal gyrus (mild) - insular cortex maintains its normal morphology without atrophic features
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ADNI_127_S_5028_MR_Accelerated_Sag_IR-SPGR__br_raw_20121114162609124_113_S174622_I346691
On a T1-weighted brain MRI of a 62-year-old male subject, we observed: For the cerebral cortex: - no observable atrophic alterations in the occipital lobe - no pathological changes consistent with atrophy detected in the frontal lobe - parietal lobe presents with a healthy appearance, free from atrophy - focal atrophy of temporal lobe on inf. temporal gyrus (between normal and mild) - insular cortex remains normal, with no signs of tissue loss - focal atrophy of limbic cortex on anterior cingulate gyrus (between mild and moderate) For the ventricles: - inf. lateral ventricle is free from enlargement or excessive growth - no enlargement observed in the 4th ventricle - no pathological changes consistent with enlargement noted in the external csf - 3rd ventricle is free from enlargement or excessive growth - the lateral ventricle shows no structural abnormalities indicative of enlargement For the subcortical structures: - no observable atrophic alterations in the pallidum - no degenerative or atrophic changes noted in the basal forebrain - no evidence of atrophy or degeneration in the putamen - thalamus appears structurally intact with no atrophic changes - the caudate shows no structural abnormalities indicative of atrophy - accumbens remains normal, with no signs of tissue loss - no pathological changes consistent with atrophy detected in the hippocampus - no evidence of atrophy or degeneration in the ventral dc - no degenerative or atrophic changes noted in the amygdala
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ADNI_031_S_4024_MR_MPRAGE_br_raw_20110425135648715_88_S105088_I228879
On a T1-weighted brain MRI of a 56-year-old female subject, we observed: For the subcortical structures: - mild bilateral hippocampus atrophy - mild atrophy of the amygdala, more pronounced on the left - no degenerative or atrophic changes noted in the accumbens - no evidence of atrophy or degeneration in the putamen - caudate appears structurally intact with no atrophic changes - thalamus appears structurally intact with no atrophic changes - pallidum appears structurally intact with no atrophic changes - basal forebrain appears structurally intact with no atrophic changes - the ventral dc shows no structural abnormalities indicative of atrophy For the cerebral cortex: - limbic cortex maintains its normal morphology without atrophic features - focal atrophy of temporal lobe on middle temporal gyrus (moderate) - focal atrophy of frontal lobe on sup. frontal gyrus (between moderate and severe) - insular cortex appears structurally intact with no atrophic changes - no degenerative or atrophic changes noted in the parietal lobe - focal atrophy of occipital lobe on middle occipital gyrus (moderate) For the ventricles: - between mild and moderate right enlargement of the lateral ventricle - 4th ventricle is free from enlargement or excessive growth - the inf. lateral ventricle shows no structural abnormalities indicative of enlargement - the 3rd ventricle shows no structural abnormalities indicative of enlargement - the external csf shows no structural abnormalities indicative of enlargement
AD
ADNI_016_S_5032_MR_Accelerated_SAG_IR-SPGR__br_raw_20121130134021740_63_S175940_I348593
On a T1-weighted brain MRI of a 78-year-old female subject, we observed: For the subcortical structures: - caudate remains normal, with no signs of tissue loss - ventral dc remains normal, with no signs of tissue loss - no pathological changes consistent with atrophy detected in the putamen - thalamus maintains its normal morphology without atrophic features - no degenerative or atrophic changes noted in the basal forebrain - pallidum presents with a healthy appearance, free from atrophy - moderate atrophy of the amygdala, more pronounced on the right - between normal and mild atrophy of the accumbens - hippocampus appears structurally intact with no atrophic changes For the ventricles: - 3rd ventricle appears structurally intact, with no evidence of enlargement - no signs of enlargement detected in the 4th ventricle - external csf appears structurally intact, with no evidence of enlargement - no pathological changes consistent with enlargement noted in the inf. lateral ventricle - lateral ventricle remains within normal size parameters, with no enlargement detected For the cerebral cortex: - no degenerative or atrophic changes noted in the insular cortex - no pathological changes consistent with atrophy detected in the occipital lobe - the temporal lobe shows no structural abnormalities indicative of atrophy - no signs of atrophy detected in the frontal lobe - the parietal lobe shows no structural abnormalities indicative of atrophy - no observable atrophic alterations in the limbic cortex
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ADNI_114_S_4379_MR_MPRAGE_br_raw_20120119121248826_98_S136145_I277487
On a T1-weighted brain MRI of a 88-year-old female subject, we observed: For the ventricles: - no observable enlargement or abnormal growth in the 4th ventricle - 3rd ventricle appears structurally intact, with no evidence of enlargement - external csf remains within normal size parameters, with no enlargement detected - no pathological changes consistent with enlargement noted in the lateral ventricle - inf. lateral ventricle is free from enlargement or excessive growth For the cerebral cortex: - frontal lobe appears structurally intact with no atrophic changes - no observable atrophic alterations in the insular cortex - moderate atrophy of the temporal lobe, more pronounced on the right, with focal volume loss observed in the following subregions: inf. temporal gyrus (between mild and moderate) and temporal pole (moderate) - occipital lobe maintains its normal morphology without atrophic features - between normal and mild atrophy of the limbic cortex - no pathological changes consistent with atrophy detected in the parietal lobe For the subcortical structures: - moderate bilateral pallidum atrophy - no signs of atrophy detected in the basal forebrain - mild left atrophy of the putamen - no pathological changes consistent with atrophy detected in the hippocampus - no degenerative or atrophic changes noted in the thalamus - between normal and mild right atrophy of the ventral dc - moderate bilateral amygdala atrophy - caudate presents with a healthy appearance, free from atrophy - between moderate and severe bilateral accumbens atrophy
AD
ADNI_126_S_4686_MR_Accelerated_Sag_IR-SPGR__br_raw_20120427123703300_117_S148519_I300822
On a T1-weighted brain MRI of a 72-year-old male subject, we observed: For the cerebral cortex: - no pathological changes consistent with atrophy detected in the parietal lobe - frontal lobe appears structurally intact with no atrophic changes - focal atrophy of insular cortex on central operculum (mild) - focal atrophy of limbic cortex on entorhinal area (moderate) - no observable atrophic alterations in the temporal lobe - focal atrophy of occipital lobe on calcarine cortex (between normal and mild) For the subcortical structures: - the pallidum shows no structural abnormalities indicative of atrophy - no signs of atrophy detected in the basal forebrain - no signs of atrophy detected in the caudate - between mild and moderate atrophy of the hippocampus, more pronounced on the left - no signs of atrophy detected in the thalamus - no signs of atrophy detected in the accumbens - no signs of atrophy detected in the putamen - no observable atrophic alterations in the ventral dc - severe bilateral amygdala atrophy For the ventricles: - external csf maintains its normal volume without signs of enlargement - the inf. lateral ventricle shows no structural abnormalities indicative of enlargement - 3rd ventricle appears structurally intact, with no evidence of enlargement - no observable enlargement or abnormal growth in the 4th ventricle - lateral ventricle maintains its normal volume without signs of enlargement
AD
ADNI_130_S_5059_MR_MPRAGE_br_raw_20130212105012862_33_S182011_I358776
On a T1-weighted brain MRI of a 73-year-old male subject, we observed: For the cerebral cortex: - focal atrophy of insular cortex on central operculum (between mild and moderate) - parietal lobe presents with a healthy appearance, free from atrophy - limbic cortex presents with a healthy appearance, free from atrophy - frontal lobe remains normal, with no signs of tissue loss - focal atrophy of occipital lobe on middle occipital gyrus (between normal and mild) - between normal and mild atrophy of the temporal lobe, with focal volume loss observed in the following subregions: middle temporal gyrus (between normal and mild) For the ventricles: - 3rd ventricle is free from enlargement or excessive growth - severe bilateral inf. lateral ventricle enlargement - no abnormal enlargement observed in the lateral ventricle - no enlargement observed in the external csf - 4th ventricle maintains its normal volume without signs of enlargement For the subcortical structures: - the putamen shows no structural abnormalities indicative of atrophy - accumbens appears structurally intact with no atrophic changes - pallidum appears structurally intact with no atrophic changes - no signs of atrophy detected in the basal forebrain - no evidence of atrophy or degeneration in the amygdala - no signs of atrophy detected in the caudate - thalamus appears structurally intact with no atrophic changes - no observable atrophic alterations in the hippocampus - the ventral dc shows no structural abnormalities indicative of atrophy
AD
ADNI_024_S_4280_MR_MPRAGE_br_raw_20111018163207473_117_S125582_I261332
On a T1-weighted brain MRI of a 80-year-old male subject, we observed: For the cerebral cortex: - insular cortex appears structurally intact with no atrophic changes - between normal and mild atrophy of the limbic cortex, more pronounced on the left, with focal volume loss observed in the following subregions: entorhinal area (mild) and parahippocampal gyrus (mild) - no signs of atrophy detected in the temporal lobe - no evidence of atrophy or degeneration in the occipital lobe - no signs of atrophy detected in the parietal lobe - focal atrophy of frontal lobe on posterior orbital gyrus (moderate) For the subcortical structures: - no degenerative or atrophic changes noted in the putamen - no pathological changes consistent with atrophy detected in the basal forebrain - no evidence of atrophy or degeneration in the pallidum - ventral dc maintains its normal morphology without atrophic features - accumbens remains normal, with no signs of tissue loss - between moderate and severe bilateral hippocampus atrophy - no signs of atrophy detected in the caudate - severe bilateral amygdala atrophy, more pronounced on the right - no degenerative or atrophic changes noted in the thalamus For the ventricles: - moderate enlargement of the external csf - the 3rd ventricle shows no structural abnormalities indicative of enlargement - 4th ventricle maintains its normal volume without signs of enlargement - lateral ventricle appears structurally intact, with no evidence of enlargement - inf. lateral ventricle is free from enlargement or excessive growth
AD
ADNI_037_S_5162_MR_MPRAGE_br_raw_20130503091904515_4_S188623_I369977
On a T1-weighted brain MRI of a 70-year-old male subject, we observed: For the cerebral cortex: - no signs of atrophy detected in the limbic cortex - mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: central operculum (mild) - no pathological changes consistent with atrophy detected in the parietal lobe - occipital lobe maintains its normal morphology without atrophic features - focal atrophy of frontal lobe on orbital inf. frontal gyrus (between normal and mild) - focal atrophy of temporal lobe on planum temporale (between normal and mild) For the subcortical structures: - hippocampus maintains its normal morphology without atrophic features - the accumbens shows no structural abnormalities indicative of atrophy - ventral dc appears structurally intact with no atrophic changes - no degenerative or atrophic changes noted in the putamen - no signs of atrophy detected in the basal forebrain - thalamus appears structurally intact with no atrophic changes - between normal and mild right atrophy of the amygdala - the caudate shows no structural abnormalities indicative of atrophy - the pallidum shows no structural abnormalities indicative of atrophy For the ventricles: - no enlargement observed in the lateral ventricle - 3rd ventricle appears structurally intact, with no evidence of enlargement - no observable enlargement or abnormal growth in the inf. lateral ventricle - the 4th ventricle shows no structural abnormalities indicative of enlargement - no observable enlargement or abnormal growth in the external csf
AD
ADNI_003_S_4142_MR_Accelerated_SAG_IR-SPGR__br_raw_20110906152028494_176_S121316_I254890
On a T1-weighted brain MRI of a 90-year-old female subject, we observed: For the subcortical structures: - no observable atrophic alterations in the thalamus - amygdala maintains its normal morphology without atrophic features - ventral dc appears structurally intact with no atrophic changes - no pathological changes consistent with atrophy detected in the accumbens - no signs of atrophy detected in the basal forebrain - caudate appears structurally intact with no atrophic changes - no signs of atrophy detected in the pallidum - no evidence of atrophy or degeneration in the putamen - hippocampus presents with a healthy appearance, free from atrophy For the cerebral cortex: - insular cortex appears structurally intact with no atrophic changes - focal atrophy of parietal lobe on precuneus (between mild and moderate) - atrophies of temporal lobe on planum temporale (between mild and moderate) and transverse temporal gyrus (moderate) - focal atrophy of frontal lobe on medial frontal cortex (mild) - atrophies of limbic cortex on anterior cingulate gyrus (between normal and mild) and posterior cingulate gyrus (severe) - occipital lobe presents with a healthy appearance, free from atrophy For the ventricles: - the lateral ventricle shows no structural abnormalities indicative of enlargement - external csf maintains its normal volume without signs of enlargement - 3rd ventricle maintains its normal volume without signs of enlargement - no abnormal enlargement observed in the inf. lateral ventricle - no signs of enlargement detected in the 4th ventricle
AD
ADNI_024_S_5054_MR_MPRAGE_br_raw_20121220180216980_73_S178405_I352573
On a T1-weighted brain MRI of a 74-year-old female subject, we observed: For the ventricles: - no pathological changes consistent with enlargement noted in the lateral ventricle - 4th ventricle remains within normal size parameters, with no enlargement detected - external csf remains within normal size parameters, with no enlargement detected - 3rd ventricle appears structurally intact, with no evidence of enlargement - severe bilateral inf. lateral ventricle enlargement For the subcortical structures: - the thalamus shows no structural abnormalities indicative of atrophy - no observable atrophic alterations in the basal forebrain - caudate appears structurally intact with no atrophic changes - no pathological changes consistent with atrophy detected in the pallidum - accumbens maintains its normal morphology without atrophic features - putamen maintains its normal morphology without atrophic features - no signs of atrophy detected in the hippocampus - no evidence of atrophy or degeneration in the amygdala - ventral dc maintains its normal morphology without atrophic features For the cerebral cortex: - parietal lobe remains normal, with no signs of tissue loss - no pathological changes consistent with atrophy detected in the insular cortex - moderate bilateral occipital lobe atrophy, with focal volume loss observed in the following subregions: occipital fusiform gyrus (mild) and occipital pole (between mild and moderate) - the temporal lobe shows no structural abnormalities indicative of atrophy - frontal lobe presents with a healthy appearance, free from atrophy - limbic cortex presents with a healthy appearance, free from atrophy
AD
ADNI_135_S_5015_MR_MPRAGE_br_raw_20121113152042237_162_S174375_I346353
On a T1-weighted brain MRI of a 78-year-old female subject, we observed: For the cerebral cortex: - focal atrophy of temporal lobe on middle temporal gyrus (moderate) - no evidence of atrophy or degeneration in the limbic cortex - no pathological changes consistent with atrophy detected in the parietal lobe - the insular cortex shows no structural abnormalities indicative of atrophy - atrophies of frontal lobe on gyrus rectus (between normal and mild) and supplementary motor cortex (between mild and moderate) - focal atrophy of occipital lobe on calcarine cortex (mild) For the ventricles: - mild enlargement of the 3rd ventricle - moderate bilateral inf. lateral ventricle enlargement - no enlargement observed in the 4th ventricle - no abnormal enlargement observed in the lateral ventricle - the external csf shows no structural abnormalities indicative of enlargement For the subcortical structures: - basal forebrain appears structurally intact with no atrophic changes - no signs of atrophy detected in the hippocampus - amygdala maintains its normal morphology without atrophic features - between mild and moderate bilateral accumbens atrophy - no observable atrophic alterations in the putamen - no pathological changes consistent with atrophy detected in the thalamus - caudate remains normal, with no signs of tissue loss - no pathological changes consistent with atrophy detected in the ventral dc - pallidum presents with a healthy appearance, free from atrophy
AD
ADNI_007_S_4911_MR_Accelerated_SAG_IR-SPGR__br_raw_20120830145649374_62_S164218_I328209
On a T1-weighted brain MRI of a 75-year-old male subject, we observed: For the subcortical structures: - thalamus appears structurally intact with no atrophic changes - no signs of atrophy detected in the pallidum - mild atrophy of the amygdala, more pronounced on the right - hippocampus maintains its normal morphology without atrophic features - ventral dc presents with a healthy appearance, free from atrophy - no signs of atrophy detected in the basal forebrain - between normal and mild right atrophy of the caudate - no degenerative or atrophic changes noted in the accumbens - putamen maintains its normal morphology without atrophic features For the cerebral cortex: - focal atrophy of limbic cortex on posterior cingulate gyrus (between mild and moderate) - atrophies of parietal lobe on angular gyrus (between mild and moderate) and precuneus (moderate) - focal atrophy of occipital lobe on occipital pole (between normal and mild) - focal atrophy of insular cortex on parietal operculum (between mild and moderate) - between moderate and severe atrophy of the temporal lobe, more pronounced on the right, with focal volume loss observed in the following subregions: middle temporal gyrus (severe) and temporal pole (between normal and mild) - focal atrophy of frontal lobe on sup. frontal gyrus medial segment (between mild and moderate) For the ventricles: - no observable enlargement or abnormal growth in the external csf - severe bilateral lateral ventricle enlargement - severe bilateral inf. lateral ventricle enlargement - 4th ventricle is free from enlargement or excessive growth - mild enlargement of the 3rd ventricle
AD
ADNI_005_S_4910_MR_Accelerated_Sag_IR-SPGR__br_raw_20120924133811005_135_S168559_I336537
On a T1-weighted brain MRI of a 82-year-old female subject, we observed: For the subcortical structures: - no degenerative or atrophic changes noted in the thalamus - between normal and mild bilateral caudate atrophy - no observable atrophic alterations in the accumbens - no degenerative or atrophic changes noted in the basal forebrain - pallidum appears structurally intact with no atrophic changes - severe bilateral amygdala atrophy, more pronounced on the right - no signs of atrophy detected in the ventral dc - moderate right atrophy of the hippocampus - the putamen shows no structural abnormalities indicative of atrophy For the cerebral cortex: - between normal and mild atrophy of the frontal lobe, with focal volume loss observed in the following subregions: gyrus rectus (between normal and mild), orbital inf. frontal gyrus (between normal and mild), medial frontal cortex (moderate) and medial orbital gyrus (mild) - between moderate and severe bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe) and posterior insula (between normal and mild) - severe bilateral temporal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: fusiform gyrus (mild), planum temporale (between moderate and severe), inf. temporal gyrus (between moderate and severe), middle temporal gyrus (moderate), sup. temporal gyrus (between moderate and severe) and temporal pole (moderate) - the parietal lobe shows no structural abnormalities indicative of atrophy - no evidence of atrophy or degeneration in the occipital lobe - between normal and mild atrophy of the limbic cortex, more pronounced on the right, with focal volume loss observed in the following subregions: anterior cingulate gyrus (between normal and mild) For the ventricles: - no enlargement observed in the 3rd ventricle - 4th ventricle is free from enlargement or excessive growth - severe bilateral inf. lateral ventricle enlargement, more pronounced on the right - between mild and moderate right enlargement of the lateral ventricle - external csf appears structurally intact, with no evidence of enlargement
AD
ADNI_036_S_4740_MR_MPRAGE_br_raw_20120531115018775_6_S151616_I306469
On a T1-weighted brain MRI of a 89-year-old male subject, we observed: For the cerebral cortex: - focal atrophy of occipital lobe on calcarine cortex (mild) - no pathological changes consistent with atrophy detected in the insular cortex - focal atrophy of temporal lobe on planum temporale (between normal and mild) - limbic cortex presents with a healthy appearance, free from atrophy - no observable atrophic alterations in the frontal lobe - focal atrophy of parietal lobe on supramarginal gyrus (between normal and mild) For the ventricles: - between mild and moderate enlargement of the 4th ventricle - the 3rd ventricle shows no structural abnormalities indicative of enlargement - inf. lateral ventricle maintains its normal volume without signs of enlargement - moderate left enlargement of the lateral ventricle - no abnormal enlargement observed in the external csf For the subcortical structures: - between mild and moderate bilateral basal forebrain atrophy - no observable atrophic alterations in the putamen - mild left atrophy of the caudate - mild left atrophy of the hippocampus - accumbens remains normal, with no signs of tissue loss - thalamus appears structurally intact with no atrophic changes - between moderate and severe bilateral ventral dc atrophy - the pallidum shows no structural abnormalities indicative of atrophy - moderate atrophy of the amygdala, more pronounced on the left
AD
ADNI_003_S_4152_MR_Accelerated_SAG_IR-SPGR__br_raw_20110831165853179_106_S120804_I253758
On a T1-weighted brain MRI of a 61-year-old male subject, we observed: For the cerebral cortex: - between normal and mild atrophy of the limbic cortex - no signs of atrophy detected in the parietal lobe - no degenerative or atrophic changes noted in the occipital lobe - no degenerative or atrophic changes noted in the insular cortex - moderate bilateral temporal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: planum temporale (between normal and mild), middle temporal gyrus (moderate), sup. temporal gyrus (mild) and temporal pole (between normal and mild) - focal atrophy of frontal lobe on middle frontal gyrus (severe) For the subcortical structures: - severe bilateral amygdala atrophy, more pronounced on the left - no observable atrophic alterations in the accumbens - ventral dc maintains its normal morphology without atrophic features - no pathological changes consistent with atrophy detected in the thalamus - no signs of atrophy detected in the hippocampus - moderate bilateral caudate atrophy, more pronounced on the left - basal forebrain appears structurally intact with no atrophic changes - no evidence of atrophy or degeneration in the pallidum - putamen maintains its normal morphology without atrophic features For the ventricles: - 4th ventricle is free from enlargement or excessive growth - between moderate and severe enlargement of the external csf - between moderate and severe bilateral inf. lateral ventricle enlargement - between mild and moderate enlargement of the 3rd ventricle - moderate left enlargement of the lateral ventricle
AD
ADNI_153_S_4172_MR_MPRAGE_br_raw_20110817113413375_135_S119196_I251187
On a T1-weighted brain MRI of a 76-year-old male subject, we observed: For the ventricles: - no abnormal enlargement observed in the lateral ventricle - 3rd ventricle remains within normal size parameters, with no enlargement detected - no observable enlargement or abnormal growth in the inf. lateral ventricle - 4th ventricle remains within normal size parameters, with no enlargement detected - external csf maintains its normal volume without signs of enlargement For the cerebral cortex: - limbic cortex remains normal, with no signs of tissue loss - frontal lobe presents with a healthy appearance, free from atrophy - focal atrophy of temporal lobe on planum temporale (between normal and mild) - between mild and moderate bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: parietal operculum (mild) - focal atrophy of parietal lobe on supramarginal gyrus (between normal and mild) - occipital lobe maintains its normal morphology without atrophic features For the subcortical structures: - between moderate and severe bilateral putamen atrophy, more pronounced on the left - between normal and mild atrophy of the accumbens, more pronounced on the left - hippocampus presents with a healthy appearance, free from atrophy - basal forebrain maintains its normal morphology without atrophic features - no observable atrophic alterations in the pallidum - moderate bilateral caudate atrophy, more pronounced on the left - no pathological changes consistent with atrophy detected in the amygdala - ventral dc appears structurally intact with no atrophic changes - thalamus appears structurally intact with no atrophic changes
AD
ADNI_068_S_4859_MR_MPRAGE_br_raw_20120807164257395_107_S159890_I322076
On a T1-weighted brain MRI of a 73-year-old male subject, we observed: For the subcortical structures: - basal forebrain remains normal, with no signs of tissue loss - no signs of atrophy detected in the caudate - pallidum maintains its normal morphology without atrophic features - ventral dc presents with a healthy appearance, free from atrophy - mild atrophy of the hippocampus, more pronounced on the right - the thalamus shows no structural abnormalities indicative of atrophy - the putamen shows no structural abnormalities indicative of atrophy - no signs of atrophy detected in the accumbens - no observable atrophic alterations in the amygdala For the cerebral cortex: - parietal lobe appears structurally intact with no atrophic changes - focal atrophy of frontal lobe on precentral gyrus (between mild and moderate) - temporal lobe maintains its normal morphology without atrophic features - occipital lobe presents with a healthy appearance, free from atrophy - no degenerative or atrophic changes noted in the limbic cortex - insular cortex presents with a healthy appearance, free from atrophy For the ventricles: - no abnormal enlargement observed in the external csf - severe bilateral inf. lateral ventricle enlargement - severe bilateral lateral ventricle enlargement - no abnormal enlargement observed in the 4th ventricle - between moderate and severe enlargement of the 3rd ventricle
AD
ADNI_130_S_4660_MR_MPRAGE_br_raw_20120423092147818_143_S148079_I300034
On a T1-weighted brain MRI of a 78-year-old female subject, we observed: For the cerebral cortex: - focal atrophy of frontal lobe on gyrus rectus (between moderate and severe) - limbic cortex presents with a healthy appearance, free from atrophy - no pathological changes consistent with atrophy detected in the parietal lobe - no observable atrophic alterations in the occipital lobe - insular cortex remains normal, with no signs of tissue loss - focal atrophy of temporal lobe on inf. temporal gyrus (between normal and mild) For the ventricles: - no pathological changes consistent with enlargement noted in the 3rd ventricle - 4th ventricle remains within normal size parameters, with no enlargement detected - no pathological changes consistent with enlargement noted in the external csf - no observable enlargement or abnormal growth in the lateral ventricle - inf. lateral ventricle maintains its normal volume without signs of enlargement For the subcortical structures: - the basal forebrain shows no structural abnormalities indicative of atrophy - mild left atrophy of the pallidum - no evidence of atrophy or degeneration in the thalamus - no signs of atrophy detected in the ventral dc - no degenerative or atrophic changes noted in the accumbens - mild right atrophy of the amygdala - no evidence of atrophy or degeneration in the caudate - between mild and moderate atrophy of the hippocampus - putamen appears structurally intact with no atrophic changes
AD
ADNI_005_S_4707_MR_Accelerated_Sag_IR-SPGR__br_raw_20120516113228861_186_S150618_I304670
On a T1-weighted brain MRI of a 68-year-old male subject, we observed: For the cerebral cortex: - no degenerative or atrophic changes noted in the limbic cortex - frontal lobe appears structurally intact with no atrophic changes - occipital lobe remains normal, with no signs of tissue loss - focal atrophy of temporal lobe on middle temporal gyrus (between normal and mild) - no evidence of atrophy or degeneration in the parietal lobe - no signs of atrophy detected in the insular cortex For the subcortical structures: - no degenerative or atrophic changes noted in the accumbens - no degenerative or atrophic changes noted in the amygdala - putamen remains normal, with no signs of tissue loss - no signs of atrophy detected in the caudate - no pathological changes consistent with atrophy detected in the ventral dc - no observable atrophic alterations in the basal forebrain - thalamus appears structurally intact with no atrophic changes - mild bilateral hippocampus atrophy - no observable atrophic alterations in the pallidum For the ventricles: - no pathological changes consistent with enlargement noted in the 3rd ventricle - no observable enlargement or abnormal growth in the 4th ventricle - no abnormal enlargement observed in the lateral ventricle - external csf appears structurally intact, with no evidence of enlargement - severe bilateral inf. lateral ventricle enlargement
AD
ADNI_067_S_5205_MR_MPRAGE_br_raw_20130617123032185_46_S192528_I376818
On a T1-weighted brain MRI of a 60-year-old female subject, we observed: For the subcortical structures: - the ventral dc shows no structural abnormalities indicative of atrophy - no signs of atrophy detected in the thalamus - no observable atrophic alterations in the caudate - accumbens remains normal, with no signs of tissue loss - moderate bilateral amygdala atrophy - putamen presents with a healthy appearance, free from atrophy - no signs of atrophy detected in the pallidum - hippocampus appears structurally intact with no atrophic changes - basal forebrain appears structurally intact with no atrophic changes For the cerebral cortex: - the limbic cortex shows no structural abnormalities indicative of atrophy - moderate bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: angular gyrus (between normal and mild), precuneus (between normal and mild) and supramarginal gyrus (between moderate and severe) - between normal and mild atrophy of the temporal lobe, more pronounced on the right - between moderate and severe bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: middle frontal gyrus (severe), anterior orbital gyrus (moderate) and sup. frontal gyrus (moderate) - insular cortex remains normal, with no signs of tissue loss - occipital lobe remains normal, with no signs of tissue loss For the ventricles: - between mild and moderate enlargement of the inf. lateral ventricle - no signs of enlargement detected in the 3rd ventricle - no abnormal enlargement observed in the 4th ventricle - between mild and moderate enlargement of the external csf - no abnormal enlargement observed in the lateral ventricle
AD
ADNI_005_S_5119_MR_Accelerated_Sag_IR-FSPGR___br_raw_20130328164636279_189_S185468_I364846
On a T1-weighted brain MRI of a 77-year-old female subject, we observed: For the subcortical structures: - no observable atrophic alterations in the accumbens - no signs of atrophy detected in the caudate - basal forebrain presents with a healthy appearance, free from atrophy - thalamus presents with a healthy appearance, free from atrophy - no signs of atrophy detected in the putamen - between normal and mild right atrophy of the hippocampus - the pallidum shows no structural abnormalities indicative of atrophy - between mild and moderate atrophy of the amygdala - ventral dc appears structurally intact with no atrophic changes For the ventricles: - between normal and mild right enlargement of the inf. lateral ventricle - no pathological changes consistent with enlargement noted in the external csf - no enlargement observed in the 4th ventricle - 3rd ventricle appears structurally intact, with no evidence of enlargement - no pathological changes consistent with enlargement noted in the lateral ventricle For the cerebral cortex: - focal atrophy of parietal lobe on angular gyrus (mild) - insular cortex presents with a healthy appearance, free from atrophy - focal atrophy of temporal lobe on middle temporal gyrus (between normal and mild) - focal atrophy of limbic cortex on anterior cingulate gyrus (mild) - no signs of atrophy detected in the occipital lobe - atrophies of frontal lobe on frontal pole (between mild and moderate) and medial frontal cortex (mild)
AD
ADNI_070_S_4719_MR_MPRAGE_br_raw_20120521142246850_171_S151143_I305573
On a T1-weighted brain MRI of a 80-year-old female subject, we observed: For the subcortical structures: - mild atrophy of the hippocampus, more pronounced on the left - ventral dc maintains its normal morphology without atrophic features - the caudate shows no structural abnormalities indicative of atrophy - moderate atrophy of the amygdala, more pronounced on the left - no observable atrophic alterations in the basal forebrain - no observable atrophic alterations in the putamen - no observable atrophic alterations in the accumbens - no observable atrophic alterations in the pallidum - no observable atrophic alterations in the thalamus For the ventricles: - 4th ventricle appears structurally intact, with no evidence of enlargement - no abnormal enlargement observed in the lateral ventricle - no enlargement observed in the external csf - moderate left enlargement of the inf. lateral ventricle - no enlargement observed in the 3rd ventricle For the cerebral cortex: - no signs of atrophy detected in the insular cortex - atrophies of parietal lobe on postcentral gyrus (between normal and mild), precuneus (between normal and mild) and sup. parietal lobule (between mild and moderate) - mild atrophy of the limbic cortex, with focal volume loss observed in the following subregions: posterior cingulate gyrus (between mild and moderate) and parahippocampal gyrus (between moderate and severe) - severe bilateral temporal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: fusiform gyrus (between mild and moderate), planum temporale (between normal and mild), sup. temporal gyrus (between normal and mild) and temporal pole (between normal and mild) - no evidence of atrophy or degeneration in the frontal lobe - no pathological changes consistent with atrophy detected in the occipital lobe
AD
ADNI_003_S_4136_MR_Accelerated_SAG_IR-SPGR__br_raw_20110811161151865_120_S118498_I250168
On a T1-weighted brain MRI of a 67-year-old male subject, we observed: For the cerebral cortex: - focal atrophy of temporal lobe on inf. temporal gyrus (moderate) - focal atrophy of insular cortex on central operculum (mild) - mild atrophy of the frontal lobe, with focal volume loss observed in the following subregions: precentral gyrus (between normal and mild) - between normal and mild atrophy of the parietal lobe, with focal volume loss observed in the following subregions: precuneus (mild) - no signs of atrophy detected in the occipital lobe - focal atrophy of limbic cortex on posterior cingulate gyrus (mild) For the ventricles: - severe bilateral lateral ventricle enlargement - no enlargement observed in the 3rd ventricle - external csf is free from enlargement or excessive growth - severe bilateral inf. lateral ventricle enlargement - 4th ventricle is free from enlargement or excessive growth For the subcortical structures: - caudate appears structurally intact with no atrophic changes - between normal and mild atrophy of the hippocampus, more pronounced on the right - ventral dc presents with a healthy appearance, free from atrophy - no degenerative or atrophic changes noted in the accumbens - no degenerative or atrophic changes noted in the thalamus - no observable atrophic alterations in the pallidum - no evidence of atrophy or degeneration in the basal forebrain - moderate atrophy of the amygdala - between normal and mild left atrophy of the putamen
AD
ADNI_019_S_4549_MR_MPRAGE_br_raw_20120424183948590_139_S148210_I300335
On a T1-weighted brain MRI of a 80-year-old male subject, we observed: For the cerebral cortex: - between normal and mild atrophy of the temporal lobe, with focal volume loss observed in the following subregions: inf. temporal gyrus (between normal and mild) and middle temporal gyrus (mild) - frontal lobe appears structurally intact with no atrophic changes - no evidence of atrophy or degeneration in the occipital lobe - atrophies of limbic cortex on entorhinal area (between normal and mild) and parahippocampal gyrus (mild) - mild atrophy of the insular cortex, with focal volume loss observed in the following subregions: anterior insula (mild) - focal atrophy of parietal lobe on angular gyrus (between normal and mild) For the ventricles: - no observable enlargement or abnormal growth in the 3rd ventricle - 4th ventricle maintains its normal volume without signs of enlargement - external csf appears structurally intact, with no evidence of enlargement - lateral ventricle remains within normal size parameters, with no enlargement detected - inf. lateral ventricle maintains its normal volume without signs of enlargement For the subcortical structures: - mild left atrophy of the hippocampus - pallidum presents with a healthy appearance, free from atrophy - the putamen shows no structural abnormalities indicative of atrophy - the caudate shows no structural abnormalities indicative of atrophy - no degenerative or atrophic changes noted in the basal forebrain - ventral dc presents with a healthy appearance, free from atrophy - amygdala presents with a healthy appearance, free from atrophy - no evidence of atrophy or degeneration in the accumbens - thalamus remains normal, with no signs of tissue loss
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ADNI_116_S_4209_MR_MPRAGE_br_raw_20110829150325078_55_S120577_I253231
On a T1-weighted brain MRI of a 78-year-old female subject, we observed: For the cerebral cortex: - frontal lobe appears structurally intact with no atrophic changes - no degenerative or atrophic changes noted in the parietal lobe - atrophies of occipital lobe on sup. occipital gyrus (between normal and mild) and occipital pole (between normal and mild) - the limbic cortex shows no structural abnormalities indicative of atrophy - insular cortex appears structurally intact with no atrophic changes - focal atrophy of temporal lobe on middle temporal gyrus (between mild and moderate) For the ventricles: - 4th ventricle is free from enlargement or excessive growth - 3rd ventricle remains within normal size parameters, with no enlargement detected - external csf is free from enlargement or excessive growth - no enlargement observed in the lateral ventricle - inf. lateral ventricle maintains its normal volume without signs of enlargement For the subcortical structures: - amygdala maintains its normal morphology without atrophic features - the ventral dc shows no structural abnormalities indicative of atrophy - no signs of atrophy detected in the accumbens - the pallidum shows no structural abnormalities indicative of atrophy - no observable atrophic alterations in the caudate - no evidence of atrophy or degeneration in the putamen - basal forebrain maintains its normal morphology without atrophic features - no observable atrophic alterations in the thalamus - hippocampus appears structurally intact with no atrophic changes
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ADNI_009_S_5027_MR_MPRAGE_br_raw_20121214085746080_45_S177647_I351495
On a T1-weighted brain MRI of a 76-year-old male subject, we observed: For the ventricles: - moderate left enlargement of the lateral ventricle - between moderate and severe bilateral inf. lateral ventricle enlargement - no enlargement observed in the 3rd ventricle - 4th ventricle is free from enlargement or excessive growth - external csf maintains its normal volume without signs of enlargement For the cerebral cortex: - no observable atrophic alterations in the frontal lobe - no signs of atrophy detected in the insular cortex - focal atrophy of temporal lobe on inf. temporal gyrus (mild) - no pathological changes consistent with atrophy detected in the parietal lobe - no signs of atrophy detected in the occipital lobe - no pathological changes consistent with atrophy detected in the limbic cortex For the subcortical structures: - pallidum remains normal, with no signs of tissue loss - no signs of atrophy detected in the thalamus - no evidence of atrophy or degeneration in the hippocampus - no evidence of atrophy or degeneration in the ventral dc - no degenerative or atrophic changes noted in the basal forebrain - accumbens remains normal, with no signs of tissue loss - no observable atrophic alterations in the caudate - the putamen shows no structural abnormalities indicative of atrophy - between mild and moderate atrophy of the amygdala, more pronounced on the left
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ADNI_006_S_4192_MR_MPRAGE_br_raw_20110928083832513_147_S123807_I258594
On a T1-weighted brain MRI of a 83-year-old male subject, we observed: For the subcortical structures: - no observable atrophic alterations in the hippocampus - ventral dc remains normal, with no signs of tissue loss - no degenerative or atrophic changes noted in the putamen - no degenerative or atrophic changes noted in the pallidum - between moderate and severe bilateral amygdala atrophy - no signs of atrophy detected in the accumbens - mild left atrophy of the basal forebrain - caudate appears structurally intact with no atrophic changes - no degenerative or atrophic changes noted in the thalamus For the ventricles: - moderate bilateral lateral ventricle enlargement - 3rd ventricle appears structurally intact, with no evidence of enlargement - between mild and moderate enlargement of the inf. lateral ventricle - no pathological changes consistent with enlargement noted in the 4th ventricle - no abnormal enlargement observed in the external csf For the cerebral cortex: - the parietal lobe shows no structural abnormalities indicative of atrophy - no degenerative or atrophic changes noted in the occipital lobe - no evidence of atrophy or degeneration in the temporal lobe - focal atrophy of insular cortex on frontal operculum (between normal and mild) - atrophies of limbic cortex on entorhinal area (moderate) and parahippocampal gyrus (between mild and moderate) - focal atrophy of frontal lobe on sup. frontal gyrus (between moderate and severe)
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ADNI_036_S_4894_MR_MPRAGE_br_raw_20120810124944746_175_S160488_I323094
On a T1-weighted brain MRI of a 61-year-old female subject, we observed: For the cerebral cortex: - no observable atrophic alterations in the insular cortex - limbic cortex presents with a healthy appearance, free from atrophy - occipital lobe appears structurally intact with no atrophic changes - mild atrophy of the temporal lobe, more pronounced on the left, with focal volume loss observed in the following subregions: inf. temporal gyrus (mild) - atrophies of frontal lobe on opercular inf. frontal gyrus (between normal and mild) and sup. frontal gyrus (moderate) - between normal and mild atrophy of the parietal lobe, with focal volume loss observed in the following subregions: supramarginal gyrus (between normal and mild) For the ventricles: - 3rd ventricle is free from enlargement or excessive growth - no observable enlargement or abnormal growth in the lateral ventricle - between mild and moderate enlargement of the inf. lateral ventricle, more pronounced on the left - 4th ventricle is free from enlargement or excessive growth - between normal and mild enlargement of the external csf For the subcortical structures: - between moderate and severe bilateral hippocampus atrophy - between mild and moderate bilateral caudate atrophy - no observable atrophic alterations in the basal forebrain - no degenerative or atrophic changes noted in the pallidum - moderate atrophy of the amygdala, more pronounced on the left - between normal and mild left atrophy of the putamen - no degenerative or atrophic changes noted in the ventral dc - thalamus maintains its normal morphology without atrophic features - no degenerative or atrophic changes noted in the accumbens
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ADNI_051_S_4980_MR_MPRAGE_br_raw_20121030084030420_50_S172619_I343041
On a T1-weighted brain MRI of a 88-year-old male subject, we observed: For the cerebral cortex: - focal atrophy of frontal lobe on subcallosal area (mild) - no signs of atrophy detected in the limbic cortex - no evidence of atrophy or degeneration in the insular cortex - parietal lobe maintains its normal morphology without atrophic features - focal atrophy of temporal lobe on planum temporale (mild) - focal atrophy of occipital lobe on inf. occipital gyrus (between mild and moderate) For the ventricles: - lateral ventricle remains within normal size parameters, with no enlargement detected - mild enlargement of the 4th ventricle - inf. lateral ventricle appears structurally intact, with no evidence of enlargement - external csf appears structurally intact, with no evidence of enlargement - 3rd ventricle remains within normal size parameters, with no enlargement detected For the subcortical structures: - no observable atrophic alterations in the putamen - no signs of atrophy detected in the amygdala - ventral dc appears structurally intact with no atrophic changes - thalamus appears structurally intact with no atrophic changes - no signs of atrophy detected in the basal forebrain - hippocampus remains normal, with no signs of tissue loss - between normal and mild left atrophy of the caudate - accumbens appears structurally intact with no atrophic changes - pallidum maintains its normal morphology without atrophic features
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ADNI_053_S_5208_MR_MPRAGE_br_raw_20130618080348968_151_S192574_I376939
On a T1-weighted brain MRI of a 69-year-old male subject, we observed: For the cerebral cortex: - between normal and mild atrophy of the occipital lobe, with focal volume loss observed in the following subregions: middle occipital gyrus (mild) and sup. occipital gyrus (between normal and mild) - focal atrophy of parietal lobe on sup. parietal lobule (mild) - focal atrophy of insular cortex on central operculum (mild) - no degenerative or atrophic changes noted in the frontal lobe - between normal and mild atrophy of the temporal lobe, more pronounced on the right, with focal volume loss observed in the following subregions: middle temporal gyrus (mild) and temporal pole (between normal and mild) - mild atrophy of the limbic cortex, with focal volume loss observed in the following subregions: entorhinal area (mild) For the subcortical structures: - between normal and mild atrophy of the ventral dc - no observable atrophic alterations in the caudate - severe bilateral amygdala atrophy, more pronounced on the right - between mild and moderate atrophy of the pallidum, more pronounced on the right - no pathological changes consistent with atrophy detected in the basal forebrain - severe bilateral hippocampus atrophy - between normal and mild right atrophy of the putamen - accumbens maintains its normal morphology without atrophic features - between normal and mild atrophy of the thalamus, more pronounced on the right For the ventricles: - between mild and moderate enlargement of the 3rd ventricle - moderate enlargement of the inf. lateral ventricle - no abnormal enlargement observed in the external csf - 4th ventricle appears structurally intact, with no evidence of enlargement - no signs of enlargement detected in the lateral ventricle
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ADNI_068_S_5206_MR_MPRAGE_br_raw_20130708131953934_142_S194175_I379376
On a T1-weighted brain MRI of a 86-year-old male subject, we observed: For the cerebral cortex: - focal atrophy of parietal lobe on postcentral gyrus medial segment (moderate) - mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: subcallosal area (between normal and mild), sup. frontal gyrus (between normal and mild) and supplementary motor cortex (mild) - atrophies of limbic cortex on entorhinal area (between normal and mild) and posterior cingulate gyrus (between normal and mild) - focal atrophy of occipital lobe on calcarine cortex (moderate) - focal atrophy of temporal lobe on inf. temporal gyrus (between moderate and severe) - between normal and mild atrophy of the insular cortex, with focal volume loss observed in the following subregions: anterior insula (between mild and moderate) For the subcortical structures: - mild atrophy of the amygdala - no signs of atrophy detected in the caudate - the accumbens shows no structural abnormalities indicative of atrophy - no observable atrophic alterations in the basal forebrain - thalamus remains normal, with no signs of tissue loss - putamen remains normal, with no signs of tissue loss - between normal and mild atrophy of the hippocampus, more pronounced on the left - ventral dc appears structurally intact with no atrophic changes - pallidum presents with a healthy appearance, free from atrophy For the ventricles: - no signs of enlargement detected in the lateral ventricle - no pathological changes consistent with enlargement noted in the 3rd ventricle - between normal and mild right enlargement of the inf. lateral ventricle - no abnormal enlargement observed in the external csf - moderate enlargement of the 4th ventricle
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ADNI_037_S_5162_MR_MPRAGE_br_raw_20130503091904515_4_S188623_I369977
On a T1-weighted brain MRI of a 70-year-old male subject, we observed: For the ventricles: - the external csf shows no structural abnormalities indicative of enlargement - inf. lateral ventricle is free from enlargement or excessive growth - no pathological changes consistent with enlargement noted in the 3rd ventricle - the 4th ventricle shows no structural abnormalities indicative of enlargement - no signs of enlargement detected in the lateral ventricle For the cerebral cortex: - no evidence of atrophy or degeneration in the limbic cortex - no degenerative or atrophic changes noted in the occipital lobe - mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: central operculum (mild) - parietal lobe maintains its normal morphology without atrophic features - focal atrophy of frontal lobe on orbital inf. frontal gyrus (between normal and mild) - focal atrophy of temporal lobe on planum temporale (between normal and mild) For the subcortical structures: - no observable atrophic alterations in the basal forebrain - no degenerative or atrophic changes noted in the accumbens - no degenerative or atrophic changes noted in the caudate - no observable atrophic alterations in the putamen - between normal and mild right atrophy of the amygdala - no degenerative or atrophic changes noted in the hippocampus - thalamus presents with a healthy appearance, free from atrophy - ventral dc maintains its normal morphology without atrophic features - no pathological changes consistent with atrophy detected in the pallidum
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ADNI_123_S_4526_MR_MPRAGE_br_raw_20120209093528861_37_S140267_I283603
On a T1-weighted brain MRI of a 80-year-old male subject, we observed: For the subcortical structures: - pallidum maintains its normal morphology without atrophic features - between normal and mild atrophy of the hippocampus, more pronounced on the left - no pathological changes consistent with atrophy detected in the putamen - accumbens presents with a healthy appearance, free from atrophy - between moderate and severe bilateral amygdala atrophy, more pronounced on the left - no evidence of atrophy or degeneration in the caudate - ventral dc maintains its normal morphology without atrophic features - basal forebrain remains normal, with no signs of tissue loss - thalamus presents with a healthy appearance, free from atrophy For the cerebral cortex: - no observable atrophic alterations in the frontal lobe - no observable atrophic alterations in the parietal lobe - no degenerative or atrophic changes noted in the occipital lobe - no pathological changes consistent with atrophy detected in the insular cortex - temporal lobe appears structurally intact with no atrophic changes - no evidence of atrophy or degeneration in the limbic cortex For the ventricles: - no abnormal enlargement observed in the external csf - 3rd ventricle is free from enlargement or excessive growth - inf. lateral ventricle is free from enlargement or excessive growth - no abnormal enlargement observed in the lateral ventricle - no observable enlargement or abnormal growth in the 4th ventricle
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ADNI_036_S_4894_MR_MPRAGE_br_raw_20120810124944746_175_S160488_I323094
On a T1-weighted brain MRI of a 61-year-old female subject, we observed: For the ventricles: - no observable enlargement or abnormal growth in the lateral ventricle - between mild and moderate enlargement of the inf. lateral ventricle, more pronounced on the left - no observable enlargement or abnormal growth in the 3rd ventricle - no enlargement observed in the 4th ventricle - between normal and mild enlargement of the external csf For the subcortical structures: - the basal forebrain shows no structural abnormalities indicative of atrophy - no pathological changes consistent with atrophy detected in the thalamus - between mild and moderate bilateral caudate atrophy - between moderate and severe bilateral hippocampus atrophy - moderate atrophy of the amygdala, more pronounced on the left - accumbens maintains its normal morphology without atrophic features - no pathological changes consistent with atrophy detected in the pallidum - between normal and mild left atrophy of the putamen - ventral dc appears structurally intact with no atrophic changes For the cerebral cortex: - atrophies of frontal lobe on opercular inf. frontal gyrus (between normal and mild) and sup. frontal gyrus (moderate) - limbic cortex presents with a healthy appearance, free from atrophy - insular cortex appears structurally intact with no atrophic changes - no observable atrophic alterations in the occipital lobe - between normal and mild atrophy of the parietal lobe, with focal volume loss observed in the following subregions: supramarginal gyrus (between normal and mild) - mild atrophy of the temporal lobe, more pronounced on the left, with focal volume loss observed in the following subregions: inf. temporal gyrus (mild)
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ADNI_068_S_4859_MR_MPRAGE_br_raw_20120807164257395_107_S159890_I322076
On a T1-weighted brain MRI of a 73-year-old male subject, we observed: For the subcortical structures: - no degenerative or atrophic changes noted in the basal forebrain - no signs of atrophy detected in the caudate - accumbens presents with a healthy appearance, free from atrophy - amygdala appears structurally intact with no atrophic changes - mild atrophy of the hippocampus, more pronounced on the right - thalamus appears structurally intact with no atrophic changes - no observable atrophic alterations in the ventral dc - the pallidum shows no structural abnormalities indicative of atrophy - putamen appears structurally intact with no atrophic changes For the cerebral cortex: - limbic cortex remains normal, with no signs of tissue loss - no degenerative or atrophic changes noted in the occipital lobe - no evidence of atrophy or degeneration in the parietal lobe - temporal lobe remains normal, with no signs of tissue loss - no evidence of atrophy or degeneration in the insular cortex - focal atrophy of frontal lobe on precentral gyrus (between mild and moderate) For the ventricles: - severe bilateral lateral ventricle enlargement - the external csf shows no structural abnormalities indicative of enlargement - between moderate and severe enlargement of the 3rd ventricle - severe bilateral inf. lateral ventricle enlargement - 4th ventricle maintains its normal volume without signs of enlargement
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ADNI_003_S_4892_MR_Accelerated_SAG_IR-SPGR__br_raw_20120827170017619_71_S162721_I326457
On a T1-weighted brain MRI of a 75-year-old female subject, we observed: For the cerebral cortex: - no signs of atrophy detected in the temporal lobe - no pathological changes consistent with atrophy detected in the insular cortex - no evidence of atrophy or degeneration in the frontal lobe - focal atrophy of parietal lobe on angular gyrus (mild) - no evidence of atrophy or degeneration in the occipital lobe - no observable atrophic alterations in the limbic cortex For the ventricles: - no pathological changes consistent with enlargement noted in the external csf - 4th ventricle is free from enlargement or excessive growth - no signs of enlargement detected in the lateral ventricle - 3rd ventricle remains within normal size parameters, with no enlargement detected - inf. lateral ventricle remains within normal size parameters, with no enlargement detected For the subcortical structures: - no degenerative or atrophic changes noted in the pallidum - no observable atrophic alterations in the accumbens - hippocampus remains normal, with no signs of tissue loss - no evidence of atrophy or degeneration in the amygdala - no evidence of atrophy or degeneration in the thalamus - between normal and mild atrophy of the basal forebrain, more pronounced on the right - the ventral dc shows no structural abnormalities indicative of atrophy - the caudate shows no structural abnormalities indicative of atrophy - the putamen shows no structural abnormalities indicative of atrophy
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ADNI_068_S_5206_MR_MPRAGE_br_raw_20130708131953934_142_S194175_I379376
On a T1-weighted brain MRI of a 86-year-old male subject, we observed: For the cerebral cortex: - focal atrophy of occipital lobe on calcarine cortex (moderate) - focal atrophy of parietal lobe on postcentral gyrus medial segment (moderate) - between normal and mild atrophy of the insular cortex, with focal volume loss observed in the following subregions: anterior insula (between mild and moderate) - atrophies of limbic cortex on entorhinal area (between normal and mild) and posterior cingulate gyrus (between normal and mild) - focal atrophy of temporal lobe on inf. temporal gyrus (between moderate and severe) - mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: subcallosal area (between normal and mild), sup. frontal gyrus (between normal and mild) and supplementary motor cortex (mild) For the subcortical structures: - ventral dc maintains its normal morphology without atrophic features - mild atrophy of the amygdala - accumbens remains normal, with no signs of tissue loss - the basal forebrain shows no structural abnormalities indicative of atrophy - caudate maintains its normal morphology without atrophic features - no signs of atrophy detected in the pallidum - no evidence of atrophy or degeneration in the thalamus - between normal and mild atrophy of the hippocampus, more pronounced on the left - putamen maintains its normal morphology without atrophic features For the ventricles: - moderate enlargement of the 4th ventricle - external csf maintains its normal volume without signs of enlargement - no abnormal enlargement observed in the lateral ventricle - no enlargement observed in the 3rd ventricle - between normal and mild right enlargement of the inf. lateral ventricle
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ADNI_068_S_5206_MR_MPRAGE_br_raw_20130708131953934_142_S194175_I379376
On a T1-weighted brain MRI of a 86-year-old male subject, we observed: For the cerebral cortex: - focal atrophy of occipital lobe on calcarine cortex (moderate) - atrophies of limbic cortex on entorhinal area (between normal and mild) and posterior cingulate gyrus (between normal and mild) - focal atrophy of temporal lobe on inf. temporal gyrus (between moderate and severe) - mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: subcallosal area (between normal and mild), sup. frontal gyrus (between normal and mild) and supplementary motor cortex (mild) - between normal and mild atrophy of the insular cortex, with focal volume loss observed in the following subregions: anterior insula (between mild and moderate) - focal atrophy of parietal lobe on postcentral gyrus medial segment (moderate) For the ventricles: - 3rd ventricle maintains its normal volume without signs of enlargement - lateral ventricle appears structurally intact, with no evidence of enlargement - moderate enlargement of the 4th ventricle - between normal and mild right enlargement of the inf. lateral ventricle - external csf is free from enlargement or excessive growth For the subcortical structures: - no degenerative or atrophic changes noted in the accumbens - basal forebrain maintains its normal morphology without atrophic features - mild atrophy of the amygdala - thalamus remains normal, with no signs of tissue loss - no signs of atrophy detected in the putamen - no signs of atrophy detected in the pallidum - caudate presents with a healthy appearance, free from atrophy - ventral dc appears structurally intact with no atrophic changes - between normal and mild atrophy of the hippocampus, more pronounced on the left
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ADNI_011_S_4906_MR_MPRAGE_br_raw_20120904143307512_81_S165942_I330056
On a T1-weighted brain MRI of a 76-year-old female subject, we observed: For the ventricles: - between normal and mild enlargement of the inf. lateral ventricle, more pronounced on the left - no pathological changes consistent with enlargement noted in the lateral ventricle - 4th ventricle is free from enlargement or excessive growth - no signs of enlargement detected in the external csf - 3rd ventricle is free from enlargement or excessive growth For the subcortical structures: - accumbens maintains its normal morphology without atrophic features - between normal and mild right atrophy of the ventral dc - basal forebrain remains normal, with no signs of tissue loss - between normal and mild atrophy of the hippocampus, more pronounced on the left - caudate appears structurally intact with no atrophic changes - the pallidum shows no structural abnormalities indicative of atrophy - thalamus maintains its normal morphology without atrophic features - no signs of atrophy detected in the amygdala - no signs of atrophy detected in the putamen For the cerebral cortex: - no evidence of atrophy or degeneration in the occipital lobe - focal atrophy of temporal lobe on sup. temporal gyrus (between mild and moderate) - limbic cortex presents with a healthy appearance, free from atrophy - no pathological changes consistent with atrophy detected in the insular cortex - frontal lobe presents with a healthy appearance, free from atrophy - parietal lobe maintains its normal morphology without atrophic features
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ADNI_037_S_4879_MR_MPRAGE_br_raw_20120913121552870_142_S167309_I333832
On a T1-weighted brain MRI of a 80-year-old female subject, we observed: For the subcortical structures: - no degenerative or atrophic changes noted in the thalamus - between mild and moderate atrophy of the amygdala - no degenerative or atrophic changes noted in the putamen - basal forebrain appears structurally intact with no atrophic changes - between normal and mild atrophy of the hippocampus - pallidum presents with a healthy appearance, free from atrophy - no degenerative or atrophic changes noted in the accumbens - the caudate shows no structural abnormalities indicative of atrophy - no evidence of atrophy or degeneration in the ventral dc For the ventricles: - no observable enlargement or abnormal growth in the lateral ventricle - no signs of enlargement detected in the 3rd ventricle - between normal and mild enlargement of the inf. lateral ventricle - no enlargement observed in the external csf - no pathological changes consistent with enlargement noted in the 4th ventricle For the cerebral cortex: - no pathological changes consistent with atrophy detected in the temporal lobe - the insular cortex shows no structural abnormalities indicative of atrophy - focal atrophy of limbic cortex on entorhinal area (between mild and moderate) - occipital lobe appears structurally intact with no atrophic changes - focal atrophy of parietal lobe on sup. parietal lobule (severe) - no observable atrophic alterations in the frontal lobe
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ADNI_009_S_5224_MR_MPRAGE_br_raw_20130717152112089_161_S195460_I381184
On a T1-weighted brain MRI of a 79-year-old male subject, we observed: For the ventricles: - no signs of enlargement detected in the external csf - between normal and mild enlargement of the inf. lateral ventricle - no observable enlargement or abnormal growth in the 3rd ventricle - 4th ventricle appears structurally intact, with no evidence of enlargement - lateral ventricle is free from enlargement or excessive growth For the cerebral cortex: - between mild and moderate atrophy of the limbic cortex, with focal volume loss observed in the following subregions: entorhinal area (severe) and parahippocampal gyrus (moderate) - between mild and moderate atrophy of the temporal lobe, more pronounced on the right, with focal volume loss observed in the following subregions: middle temporal gyrus (between mild and moderate) and temporal pole (between moderate and severe) - between normal and mild atrophy of the insular cortex, more pronounced on the right - parietal lobe presents with a healthy appearance, free from atrophy - focal atrophy of occipital lobe on inf. occipital gyrus (mild) - frontal lobe maintains its normal morphology without atrophic features For the subcortical structures: - putamen presents with a healthy appearance, free from atrophy - no observable atrophic alterations in the basal forebrain - between normal and mild right atrophy of the ventral dc - pallidum maintains its normal morphology without atrophic features - accumbens remains normal, with no signs of tissue loss - mild atrophy of the hippocampus - severe bilateral amygdala atrophy, more pronounced on the right - no evidence of atrophy or degeneration in the caudate - thalamus appears structurally intact with no atrophic changes
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ADNI_003_S_4142_MR_Accelerated_SAG_IR-SPGR__br_raw_20110906152028494_176_S121316_I254890
On a T1-weighted brain MRI of a 90-year-old female subject, we observed: For the cerebral cortex: - focal atrophy of parietal lobe on precuneus (between mild and moderate) - atrophies of limbic cortex on anterior cingulate gyrus (between normal and mild) and posterior cingulate gyrus (severe) - atrophies of temporal lobe on planum temporale (between mild and moderate) and transverse temporal gyrus (moderate) - focal atrophy of frontal lobe on medial frontal cortex (mild) - no signs of atrophy detected in the insular cortex - no evidence of atrophy or degeneration in the occipital lobe For the subcortical structures: - putamen maintains its normal morphology without atrophic features - no degenerative or atrophic changes noted in the basal forebrain - thalamus maintains its normal morphology without atrophic features - no degenerative or atrophic changes noted in the caudate - pallidum presents with a healthy appearance, free from atrophy - no observable atrophic alterations in the amygdala - ventral dc appears structurally intact with no atrophic changes - no signs of atrophy detected in the accumbens - no signs of atrophy detected in the hippocampus For the ventricles: - the lateral ventricle shows no structural abnormalities indicative of enlargement - external csf remains within normal size parameters, with no enlargement detected - no signs of enlargement detected in the inf. lateral ventricle - 4th ventricle appears structurally intact, with no evidence of enlargement - no enlargement observed in the 3rd ventricle
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ADNI_073_S_4853_MR_MPRAGE_br_raw_20120711181405636_32_S157321_I315948
On a T1-weighted brain MRI of a 71-year-old female subject, we observed: For the cerebral cortex: - moderate atrophy of the temporal lobe, more pronounced on the right, with focal volume loss observed in the following subregions: middle temporal gyrus (moderate) - between mild and moderate bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: sup. frontal gyrus (between normal and mild) and sup. frontal gyrus medial segment (between mild and moderate) - parietal lobe maintains its normal morphology without atrophic features - mild atrophy of the limbic cortex - atrophies of insular cortex on posterior insula (mild) and central operculum (between normal and mild) - occipital lobe presents with a healthy appearance, free from atrophy For the ventricles: - 3rd ventricle remains within normal size parameters, with no enlargement detected - lateral ventricle maintains its normal volume without signs of enlargement - inf. lateral ventricle remains within normal size parameters, with no enlargement detected - no pathological changes consistent with enlargement noted in the 4th ventricle - between moderate and severe enlargement of the external csf For the subcortical structures: - between normal and mild atrophy of the accumbens - between normal and mild atrophy of the hippocampus, more pronounced on the right - no pathological changes consistent with atrophy detected in the pallidum - thalamus remains normal, with no signs of tissue loss - the putamen shows no structural abnormalities indicative of atrophy - no degenerative or atrophic changes noted in the caudate - between mild and moderate bilateral ventral dc atrophy - between normal and mild atrophy of the amygdala, more pronounced on the right - no pathological changes consistent with atrophy detected in the basal forebrain
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ADNI_014_S_4615_MR_MPRAGE_br_raw_20120330084522944_163_S145232_I294334
On a T1-weighted brain MRI of a 87-year-old male subject, we observed: For the ventricles: - between normal and mild enlargement of the inf. lateral ventricle - 3rd ventricle maintains its normal volume without signs of enlargement - no abnormal enlargement observed in the 4th ventricle - no observable enlargement or abnormal growth in the lateral ventricle - external csf appears structurally intact, with no evidence of enlargement For the cerebral cortex: - limbic cortex remains normal, with no signs of tissue loss - no observable atrophic alterations in the occipital lobe - no observable atrophic alterations in the frontal lobe - no signs of atrophy detected in the insular cortex - focal atrophy of temporal lobe on temporal pole (between normal and mild) - no degenerative or atrophic changes noted in the parietal lobe For the subcortical structures: - thalamus maintains its normal morphology without atrophic features - pallidum presents with a healthy appearance, free from atrophy - caudate appears structurally intact with no atrophic changes - no pathological changes consistent with atrophy detected in the accumbens - mild atrophy of the hippocampus, more pronounced on the left - moderate bilateral amygdala atrophy, more pronounced on the left - between normal and mild atrophy of the basal forebrain, more pronounced on the left - ventral dc remains normal, with no signs of tissue loss - putamen remains normal, with no signs of tissue loss
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ADNI_010_S_5163_MR_MPRAGE_br_raw_20130606120905404_67_S191475_I375336
On a T1-weighted brain MRI of a 67-year-old male subject, we observed: For the subcortical structures: - pallidum presents with a healthy appearance, free from atrophy - putamen presents with a healthy appearance, free from atrophy - hippocampus maintains its normal morphology without atrophic features - accumbens presents with a healthy appearance, free from atrophy - between normal and mild atrophy of the amygdala - basal forebrain remains normal, with no signs of tissue loss - no degenerative or atrophic changes noted in the thalamus - caudate maintains its normal morphology without atrophic features - ventral dc presents with a healthy appearance, free from atrophy For the cerebral cortex: - no observable atrophic alterations in the occipital lobe - focal atrophy of temporal lobe on inf. temporal gyrus (mild) - no degenerative or atrophic changes noted in the insular cortex - the limbic cortex shows no structural abnormalities indicative of atrophy - moderate bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: gyrus rectus (between mild and moderate), opercular inf. frontal gyrus (between mild and moderate), middle frontal gyrus (moderate) and medial orbital gyrus (moderate) - no signs of atrophy detected in the parietal lobe For the ventricles: - between mild and moderate enlargement of the external csf - no signs of enlargement detected in the inf. lateral ventricle - no abnormal enlargement observed in the 4th ventricle - no signs of enlargement detected in the lateral ventricle - the 3rd ventricle shows no structural abnormalities indicative of enlargement
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ADNI_073_S_4853_MR_MPRAGE_br_raw_20120711181405636_32_S157321_I315948
On a T1-weighted brain MRI of a 71-year-old female subject, we observed: For the subcortical structures: - between normal and mild atrophy of the hippocampus, more pronounced on the right - no observable atrophic alterations in the pallidum - no observable atrophic alterations in the caudate - between mild and moderate bilateral ventral dc atrophy - no evidence of atrophy or degeneration in the putamen - thalamus appears structurally intact with no atrophic changes - between normal and mild atrophy of the amygdala, more pronounced on the right - basal forebrain maintains its normal morphology without atrophic features - between normal and mild atrophy of the accumbens For the ventricles: - no observable enlargement or abnormal growth in the 4th ventricle - between moderate and severe enlargement of the external csf - the inf. lateral ventricle shows no structural abnormalities indicative of enlargement - 3rd ventricle maintains its normal volume without signs of enlargement - lateral ventricle appears structurally intact, with no evidence of enlargement For the cerebral cortex: - moderate atrophy of the temporal lobe, more pronounced on the right, with focal volume loss observed in the following subregions: middle temporal gyrus (moderate) - no evidence of atrophy or degeneration in the occipital lobe - between mild and moderate bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: sup. frontal gyrus (between normal and mild) and sup. frontal gyrus medial segment (between mild and moderate) - mild atrophy of the limbic cortex - no observable atrophic alterations in the parietal lobe - atrophies of insular cortex on posterior insula (mild) and central operculum (between normal and mild)
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ADNI_067_S_5205_MR_MPRAGE_br_raw_20130617123032185_46_S192528_I376818
On a T1-weighted brain MRI of a 60-year-old female subject, we observed: For the ventricles: - 3rd ventricle maintains its normal volume without signs of enlargement - between mild and moderate enlargement of the external csf - no pathological changes consistent with enlargement noted in the lateral ventricle - no observable enlargement or abnormal growth in the 4th ventricle - between mild and moderate enlargement of the inf. lateral ventricle For the cerebral cortex: - moderate bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: angular gyrus (between normal and mild), precuneus (between normal and mild) and supramarginal gyrus (between moderate and severe) - occipital lobe appears structurally intact with no atrophic changes - limbic cortex remains normal, with no signs of tissue loss - between moderate and severe bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: middle frontal gyrus (severe), anterior orbital gyrus (moderate) and sup. frontal gyrus (moderate) - between normal and mild atrophy of the temporal lobe, more pronounced on the right - no signs of atrophy detected in the insular cortex For the subcortical structures: - caudate maintains its normal morphology without atrophic features - the putamen shows no structural abnormalities indicative of atrophy - moderate bilateral amygdala atrophy - basal forebrain presents with a healthy appearance, free from atrophy - the pallidum shows no structural abnormalities indicative of atrophy - hippocampus presents with a healthy appearance, free from atrophy - accumbens appears structurally intact with no atrophic changes - no evidence of atrophy or degeneration in the thalamus - no observable atrophic alterations in the ventral dc
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ADNI_153_S_4172_MR_MPRAGE_br_raw_20110817113413375_135_S119196_I251187
On a T1-weighted brain MRI of a 76-year-old male subject, we observed: For the subcortical structures: - thalamus appears structurally intact with no atrophic changes - between moderate and severe bilateral putamen atrophy, more pronounced on the left - amygdala remains normal, with no signs of tissue loss - no degenerative or atrophic changes noted in the ventral dc - no observable atrophic alterations in the basal forebrain - no evidence of atrophy or degeneration in the hippocampus - moderate bilateral caudate atrophy, more pronounced on the left - between normal and mild atrophy of the accumbens, more pronounced on the left - no signs of atrophy detected in the pallidum For the ventricles: - no observable enlargement or abnormal growth in the 4th ventricle - no pathological changes consistent with enlargement noted in the external csf - lateral ventricle appears structurally intact, with no evidence of enlargement - inf. lateral ventricle appears structurally intact, with no evidence of enlargement - no pathological changes consistent with enlargement noted in the 3rd ventricle For the cerebral cortex: - focal atrophy of parietal lobe on supramarginal gyrus (between normal and mild) - occipital lobe remains normal, with no signs of tissue loss - focal atrophy of temporal lobe on planum temporale (between normal and mild) - frontal lobe remains normal, with no signs of tissue loss - limbic cortex maintains its normal morphology without atrophic features - between mild and moderate bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: parietal operculum (mild)
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ADNI_003_S_4892_MR_Accelerated_SAG_IR-SPGR__br_raw_20120827170017619_71_S162721_I326457
On a T1-weighted brain MRI of a 75-year-old female subject, we observed: For the cerebral cortex: - the insular cortex shows no structural abnormalities indicative of atrophy - frontal lobe remains normal, with no signs of tissue loss - focal atrophy of parietal lobe on angular gyrus (mild) - no degenerative or atrophic changes noted in the occipital lobe - no evidence of atrophy or degeneration in the limbic cortex - no evidence of atrophy or degeneration in the temporal lobe For the ventricles: - no signs of enlargement detected in the lateral ventricle - inf. lateral ventricle is free from enlargement or excessive growth - no signs of enlargement detected in the 3rd ventricle - external csf maintains its normal volume without signs of enlargement - 4th ventricle is free from enlargement or excessive growth For the subcortical structures: - between normal and mild atrophy of the basal forebrain, more pronounced on the right - pallidum maintains its normal morphology without atrophic features - caudate remains normal, with no signs of tissue loss - hippocampus remains normal, with no signs of tissue loss - no evidence of atrophy or degeneration in the thalamus - accumbens presents with a healthy appearance, free from atrophy - putamen appears structurally intact with no atrophic changes - no degenerative or atrophic changes noted in the amygdala - no pathological changes consistent with atrophy detected in the ventral dc
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ADNI_126_S_4494_MR_Accelerated_Sag_IR-SPGR__br_raw_20120131123025629_91_S138966_I281601
On a T1-weighted brain MRI of a 71-year-old male subject, we observed: For the subcortical structures: - pallidum appears structurally intact with no atrophic changes - caudate maintains its normal morphology without atrophic features - severe bilateral amygdala atrophy - no signs of atrophy detected in the accumbens - between mild and moderate bilateral hippocampus atrophy - basal forebrain remains normal, with no signs of tissue loss - no observable atrophic alterations in the thalamus - no degenerative or atrophic changes noted in the putamen - no degenerative or atrophic changes noted in the ventral dc For the cerebral cortex: - no observable atrophic alterations in the parietal lobe - frontal lobe presents with a healthy appearance, free from atrophy - occipital lobe remains normal, with no signs of tissue loss - focal atrophy of limbic cortex on entorhinal area (between mild and moderate) - temporal lobe remains normal, with no signs of tissue loss - insular cortex remains normal, with no signs of tissue loss For the ventricles: - lateral ventricle maintains its normal volume without signs of enlargement - no abnormal enlargement observed in the 3rd ventricle - the external csf shows no structural abnormalities indicative of enlargement - mild right enlargement of the inf. lateral ventricle - no observable enlargement or abnormal growth in the 4th ventricle
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ADNI_036_S_4740_MR_MPRAGE_br_raw_20120531115018775_6_S151616_I306469
On a T1-weighted brain MRI of a 89-year-old male subject, we observed: For the ventricles: - moderate left enlargement of the lateral ventricle - inf. lateral ventricle remains within normal size parameters, with no enlargement detected - external csf remains within normal size parameters, with no enlargement detected - between mild and moderate enlargement of the 4th ventricle - 3rd ventricle maintains its normal volume without signs of enlargement For the cerebral cortex: - focal atrophy of temporal lobe on planum temporale (between normal and mild) - focal atrophy of parietal lobe on supramarginal gyrus (between normal and mild) - frontal lobe remains normal, with no signs of tissue loss - no degenerative or atrophic changes noted in the limbic cortex - focal atrophy of occipital lobe on calcarine cortex (mild) - no pathological changes consistent with atrophy detected in the insular cortex For the subcortical structures: - no pathological changes consistent with atrophy detected in the pallidum - between moderate and severe bilateral ventral dc atrophy - moderate atrophy of the amygdala, more pronounced on the left - putamen maintains its normal morphology without atrophic features - mild left atrophy of the hippocampus - mild left atrophy of the caudate - accumbens maintains its normal morphology without atrophic features - between mild and moderate bilateral basal forebrain atrophy - no degenerative or atrophic changes noted in the thalamus
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ADNI_009_S_5224_MR_MPRAGE_br_raw_20130717152112089_161_S195460_I381184
On a T1-weighted brain MRI of a 79-year-old male subject, we observed: For the ventricles: - lateral ventricle is free from enlargement or excessive growth - no signs of enlargement detected in the 4th ventricle - external csf appears structurally intact, with no evidence of enlargement - 3rd ventricle remains within normal size parameters, with no enlargement detected - between normal and mild enlargement of the inf. lateral ventricle For the cerebral cortex: - between mild and moderate atrophy of the limbic cortex, with focal volume loss observed in the following subregions: entorhinal area (severe) and parahippocampal gyrus (moderate) - between mild and moderate atrophy of the temporal lobe, more pronounced on the right, with focal volume loss observed in the following subregions: middle temporal gyrus (between mild and moderate) and temporal pole (between moderate and severe) - focal atrophy of occipital lobe on inf. occipital gyrus (mild) - between normal and mild atrophy of the insular cortex, more pronounced on the right - the frontal lobe shows no structural abnormalities indicative of atrophy - the parietal lobe shows no structural abnormalities indicative of atrophy For the subcortical structures: - mild atrophy of the hippocampus - caudate remains normal, with no signs of tissue loss - between normal and mild right atrophy of the ventral dc - no signs of atrophy detected in the basal forebrain - no pathological changes consistent with atrophy detected in the accumbens - no signs of atrophy detected in the thalamus - no evidence of atrophy or degeneration in the pallidum - severe bilateral amygdala atrophy, more pronounced on the right - no degenerative or atrophic changes noted in the putamen
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ADNI_126_S_4686_MR_Accelerated_Sag_IR-SPGR__br_raw_20120427123703300_117_S148519_I300822
On a T1-weighted brain MRI of a 72-year-old male subject, we observed: For the subcortical structures: - no observable atrophic alterations in the caudate - the basal forebrain shows no structural abnormalities indicative of atrophy - no signs of atrophy detected in the accumbens - between mild and moderate atrophy of the hippocampus, more pronounced on the left - no degenerative or atrophic changes noted in the thalamus - severe bilateral amygdala atrophy - no degenerative or atrophic changes noted in the ventral dc - no observable atrophic alterations in the putamen - no degenerative or atrophic changes noted in the pallidum For the ventricles: - no signs of enlargement detected in the 4th ventricle - no enlargement observed in the lateral ventricle - inf. lateral ventricle remains within normal size parameters, with no enlargement detected - no enlargement observed in the 3rd ventricle - no signs of enlargement detected in the external csf For the cerebral cortex: - parietal lobe remains normal, with no signs of tissue loss - focal atrophy of limbic cortex on entorhinal area (moderate) - focal atrophy of insular cortex on central operculum (mild) - focal atrophy of occipital lobe on calcarine cortex (between normal and mild) - frontal lobe remains normal, with no signs of tissue loss - no signs of atrophy detected in the temporal lobe
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ADNI_003_S_4152_MR_Accelerated_SAG_IR-SPGR__br_raw_20110831165853179_106_S120804_I253758
On a T1-weighted brain MRI of a 61-year-old male subject, we observed: For the cerebral cortex: - moderate bilateral temporal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: planum temporale (between normal and mild), middle temporal gyrus (moderate), sup. temporal gyrus (mild) and temporal pole (between normal and mild) - occipital lobe appears structurally intact with no atrophic changes - focal atrophy of frontal lobe on middle frontal gyrus (severe) - between normal and mild atrophy of the limbic cortex - no degenerative or atrophic changes noted in the parietal lobe - insular cortex remains normal, with no signs of tissue loss For the ventricles: - between mild and moderate enlargement of the 3rd ventricle - no pathological changes consistent with enlargement noted in the 4th ventricle - between moderate and severe enlargement of the external csf - between moderate and severe bilateral inf. lateral ventricle enlargement - moderate left enlargement of the lateral ventricle For the subcortical structures: - pallidum maintains its normal morphology without atrophic features - severe bilateral amygdala atrophy, more pronounced on the left - the ventral dc shows no structural abnormalities indicative of atrophy - moderate bilateral caudate atrophy, more pronounced on the left - the thalamus shows no structural abnormalities indicative of atrophy - no degenerative or atrophic changes noted in the putamen - no signs of atrophy detected in the basal forebrain - no evidence of atrophy or degeneration in the accumbens - no evidence of atrophy or degeneration in the hippocampus
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ADNI_007_S_4568_MR_Accelerated_SAG_IR-SPGR__br_raw_20120301171636342_136_S142282_I287481
On a T1-weighted brain MRI of a 71-year-old female subject, we observed: For the subcortical structures: - no degenerative or atrophic changes noted in the thalamus - between moderate and severe bilateral amygdala atrophy - mild bilateral ventral dc atrophy - putamen presents with a healthy appearance, free from atrophy - between normal and mild atrophy of the pallidum - mild left atrophy of the accumbens - no evidence of atrophy or degeneration in the basal forebrain - hippocampus presents with a healthy appearance, free from atrophy - caudate remains normal, with no signs of tissue loss For the cerebral cortex: - focal atrophy of occipital lobe on occipital pole (mild) - no degenerative or atrophic changes noted in the insular cortex - limbic cortex presents with a healthy appearance, free from atrophy - the temporal lobe shows no structural abnormalities indicative of atrophy - no evidence of atrophy or degeneration in the frontal lobe - mild atrophy of the parietal lobe, with focal volume loss observed in the following subregions: sup. parietal lobule (severe) For the ventricles: - 3rd ventricle appears structurally intact, with no evidence of enlargement - inf. lateral ventricle is free from enlargement or excessive growth - external csf remains within normal size parameters, with no enlargement detected - lateral ventricle remains within normal size parameters, with no enlargement detected - no enlargement observed in the 4th ventricle
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ADNI_153_S_4172_MR_MPRAGE_br_raw_20110817113413375_135_S119196_I251187
On a T1-weighted brain MRI of a 76-year-old male subject, we observed: For the cerebral cortex: - occipital lobe remains normal, with no signs of tissue loss - limbic cortex maintains its normal morphology without atrophic features - between mild and moderate bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: parietal operculum (mild) - focal atrophy of parietal lobe on supramarginal gyrus (between normal and mild) - focal atrophy of temporal lobe on planum temporale (between normal and mild) - frontal lobe presents with a healthy appearance, free from atrophy For the subcortical structures: - no evidence of atrophy or degeneration in the amygdala - no signs of atrophy detected in the ventral dc - no evidence of atrophy or degeneration in the thalamus - pallidum maintains its normal morphology without atrophic features - no observable atrophic alterations in the basal forebrain - between moderate and severe bilateral putamen atrophy, more pronounced on the left - moderate bilateral caudate atrophy, more pronounced on the left - no observable atrophic alterations in the hippocampus - between normal and mild atrophy of the accumbens, more pronounced on the left For the ventricles: - no enlargement observed in the lateral ventricle - no observable enlargement or abnormal growth in the 3rd ventricle - no signs of enlargement detected in the 4th ventricle - no signs of enlargement detected in the external csf - the inf. lateral ventricle shows no structural abnormalities indicative of enlargement
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