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[ { "content": "Is anorectal endosonography valuable in dyschesia?", "role": "user" }, { "content": "Is anorectal endosonography helpful for patients with dyschesia?", "role": "assistant" } ]

[ { "content": "Is there a connection between sublingual varices and hypertension?", "role": "user" }, { "content": "Do sublingual varices have a link to high blood pressure?", "role": "assistant" } ]

[ { "content": "Is the affinity column-mediated immunoassay method suitable as an alternative to the microparticle enzyme immunoassay method as a blood tacrolimus assay?", "role": "user" }, { "content": "Can affinity column-mediated immunoassay replace microparticle enzyme immunoassay for measuring blood tacrolimus levels?", "role": "assistant" } ]

[ { "content": "Does a physician's specialty influence the recording of medication history in patients' case notes?", "role": "user" }, { "content": "Does a doctor's area of specialization impact how medication history is documented in patient records?", "role": "assistant" } ]

[ { "content": "Locoregional opening of the rodent blood-brain barrier for paclitaxel using Nd:YAG laser-induced thermo therapy: a new concept of adjuvant glioma therapy?", "role": "user" }, { "content": "Here is a paraphrased version of the text:\n\nCould laser-induced heat treatment using Nd:YAG open the blood-brain barrier in rodents for paclitaxel, offering a novel approach to glioma treatment?", "role": "assistant" } ]

[ { "content": "Spinal subdural hematoma: a sequela of a ruptured intracranial aneurysm?", "role": "user" }, { "content": "Can a spinal subdural hematoma be a complication of a ruptured intracranial aneurysm?", "role": "assistant" } ]

[ { "content": "Is there a correlation between androgens and sexual desire in women?", "role": "user" }, { "content": "Do androgens play a role in influencing female libido?", "role": "assistant" } ]

[ { "content": "Is the zeolite hemostatic agent beneficial in reducing blood loss during arterial injury?", "role": "user" }, { "content": "Does the use of zeolite hemostatic agent help minimize bleeding in cases of arterial injury?", "role": "assistant" } ]

[ { "content": "Are endothelial cell patterns of astrocytomas indicative of grade?", "role": "user" }, { "content": "Do endothelial cell patterns in astrocytomas reflect tumor grade?", "role": "assistant" } ]

[ { "content": "Should cavitation in proximal surfaces be reported in cone beam computed tomography examination?", "role": "user" }, { "content": "Is cavitation on proximal surfaces visible in cone beam computed tomography scans worth reporting?", "role": "assistant" } ]

[ { "content": "Ultrasound in squamous cell carcinoma of the penis; a useful addition to clinical staging?", "role": "user" }, { "content": "Is ultrasound a valuable tool in staging squamous cell carcinoma of the penis?", "role": "assistant" } ]

[ { "content": "Can third trimester ultrasound predict the presentation of the first twin at delivery?", "role": "user" }, { "content": "Is it possible for a third trimester ultrasound to determine the birth position of the first twin?", "role": "assistant" } ]

[ { "content": "Is micro-computed tomography reliable to determine the microstructure of the maxillary alveolar bone?", "role": "user" }, { "content": "Can micro-computed tomography be relied upon to assess the microstructure of the maxillary alveolar bone?", "role": "assistant" } ]

[ { "content": "Is primary angioplasty an acceptable alternative to thrombolysis?", "role": "user" }, { "content": "Is primary angioplasty a viable substitute for thrombolysis?", "role": "assistant" } ]

[ { "content": "Is endometrial polyp formation associated with increased expression of vascular endothelial growth factor and transforming growth factor-beta1?", "role": "user" }, { "content": "Does the formation of endometrial polyps correlate with higher levels of vascular endothelial growth factor and transforming growth factor-beta1?", "role": "assistant" } ]

[ { "content": "Improvements in survival of gynaecological cancer in the Anglia region of England: are these an effect of centralisation of care and use of multidisciplinary management?", "role": "user" }, { "content": "Have improvements in gynaecological cancer survival rates in England's Anglia region resulted from centralised care and multidisciplinary management?", "role": "assistant" } ]

[ { "content": "Estimated fetal weight by ultrasound: a modifiable risk factor for cesarean delivery?", "role": "user" }, { "content": "Can ultrasound-estimated fetal weight be a risk factor for cesarean delivery that can be modified?", "role": "assistant" } ]

[ { "content": "Are financial incentives cost-effective to support smoking cessation during pregnancy?", "role": "user" }, { "content": "Do financial incentives provide a cost-effective way to help pregnant women quit smoking?", "role": "assistant" } ]

[ { "content": "Do adjuvant aromatase inhibitors increase the cardiovascular risk in postmenopausal women with early breast cancer?", "role": "user" }, { "content": "Do aromatase inhibitors given as adjuvants increase cardiovascular risk in postmenopausal women with early stage breast cancer?", "role": "assistant" } ]

[ { "content": "Is fear of anaphylactic shock discouraging surgeons from more widely adopting percutaneous and laparoscopic techniques in the treatment of liver hydatid cyst?", "role": "user" }, { "content": "Are surgeons being deterred from adopting minimally invasive techniques for liver hydatid cyst treatment due to the risk of anaphylactic shock?", "role": "assistant" } ]

[ { "content": "Risk stratification in emergency surgical patients: is the APACHE II score a reliable marker of physiological impairment?", "role": "user" }, { "content": "Is the APACHE II score a reliable indicator of physiological impairment in emergency surgical patients?", "role": "assistant" } ]

[ { "content": "Can Flexible Instruments Create Adequate Femoral Tunnel Lengths at 90° of Knee Flexion in Anterior Cruciate Ligament Reconstruction?", "role": "user" }, { "content": "Do flexible instruments allow for sufficient femoral tunnel lengths during ACL reconstruction when the knee is bent at a 90-degree angle?", "role": "assistant" } ]

[ { "content": "Do mitochondria play a role in remodelling lace plant leaves during programmed cell death?", "role": "user" }, { "content": "Are mitochondria involved in the remodelling of lace plant leaves during programmed cell death?", "role": "assistant" } ]

[ { "content": "\"Occult\" posttraumatic lesions of the knee: can magnetic resonance substitute for diagnostic arthroscopy?", "role": "user" }, { "content": "Can MRI replace diagnostic arthroscopy for hidden posttraumatic knee lesions?", "role": "assistant" } ]

[ { "content": "Does Sensation Return to the Nasal Tip After Microfat Grafting?", "role": "user" }, { "content": "Can Nasal Tip Sensation Be Restored Through Microfat Grafting?", "role": "assistant" } ]

[ { "content": "Do some U.S. states have higher/lower injury mortality rates than others?", "role": "user" }, { "content": "Is there variation in injury mortality rates across different U.S. states?", "role": "assistant" } ]

[ { "content": "Hepatorenal syndrome: are we missing some prognostic factors?", "role": "user" }, { "content": "Are there prognostic factors for hepatorenal syndrome that we are overlooking?", "role": "assistant" } ]

[ { "content": "The Main Gate Syndrome: a new format in mass-casualty victim \"surge\" management?", "role": "user" }, { "content": "Could the Main Gate Syndrome be a new format for managing mass-casualty victim \"surge\"?", "role": "assistant" } ]

[ { "content": "Is EQ-5D a valid quality of life instrument in patients with acute coronary syndrome?", "role": "user" }, { "content": "Is the EQ-5D a reliable tool for measuring quality of life in patients with acute coronary syndrome?", "role": "assistant" } ]

[ { "content": "Is portable ultrasonography accurate in the evaluation of Schanz pin placement during extremity fracture fixation in austere environments?", "role": "user" }, { "content": "Does portable ultrasonography provide accurate assessment of Schanz pin placement in extremity fracture fixation, particularly in resource-limited settings?", "role": "assistant" } ]

[ { "content": "Is grandmultiparity an independent risk factor for adverse perinatal outcomes?", "role": "user" }, { "content": "Does grand multiparity increase the risk of adverse perinatal outcomes independently?", "role": "assistant" } ]

[ { "content": "Does depression diagnosis and antidepressant prescribing vary by location?", "role": "user" }, { "content": "Do geographic locations influence depression diagnosis and antidepressant prescription rates?", "role": "assistant" } ]

[ { "content": "Learning needs of postpartum women: does socioeconomic status matter?", "role": "user" }, { "content": "Does socioeconomic status influence the learning needs of postpartum women?", "role": "assistant" } ]

[ { "content": "Is there a differential in the dental health of new recruits to the British Armed Forces?", "role": "user" }, { "content": "Do new British Armed Forces recruits exhibit disparities in dental health?", "role": "assistant" } ]

[ { "content": "Do patients with rheumatoid arthritis established on methotrexate and folic acid 5 mg daily need to continue folic acid supplements long term?", "role": "user" }, { "content": "Is long-term folic acid supplementation necessary for rheumatoid arthritis patients already taking methotrexate and 5mg of folic acid daily?", "role": "assistant" } ]

[ { "content": "Can teaching medical students to investigate medication errors change their attitudes towards patient safety?", "role": "user" }, { "content": "Does teaching medical students to investigate medication errors impact their perception of patient safety?", "role": "assistant" } ]

[ { "content": "Does a delay in transfer to a rehabilitation unit for older people affect outcome after fracture of the proximal femur?", "role": "user" }, { "content": "Can delayed transfer to a rehabilitation unit for older adults impact the outcome following a proximal femur fracture?", "role": "assistant" } ]

[ { "content": "Are there gender differences in the reasons why African Americans delay in seeking medical help for symptoms of an acute myocardial infarction?", "role": "user" }, { "content": "Do gender differences exist in the reasons African Americans postpone seeking medical attention for acute myocardial infarction symptoms?", "role": "assistant" } ]

[ { "content": "Does ambulatory process of care predict health-related quality of life outcomes for patients with chronic disease?", "role": "user" }, { "content": "Can ambulatory care processes influence health-related quality of life in patients with chronic diseases?", "role": "assistant" } ]

[ { "content": "Is the combination with 2-methoxyestradiol able to reduce the dosages of chemotherapeutices in the treatment of human ovarian cancer?", "role": "user" }, { "content": "Can combining 2-methoxyestradiol with chemotherapy decrease the required doses for treating human ovarian cancer?", "role": "assistant" } ]

[ { "content": "Does a dedicated discharge coordinator improve the quality of hospital discharge?", "role": "user" }, { "content": "Can a dedicated discharge coordinator enhance hospital discharge quality?", "role": "assistant" } ]

[ { "content": "Impact of MPH programs: contributing to health system strengthening in low- and middle-income countries?", "role": "user" }, { "content": "Do MPH programs play a role in strengthening health systems in low- and middle-income countries?", "role": "assistant" } ]

[ { "content": "Pap smears with glandular cell abnormalities: Are they detected by rapid prescreening?", "role": "user" }, { "content": "Can rapid prescreening detect Pap smears with glandular cell abnormalities?", "role": "assistant" } ]

[ { "content": "Can transcranial direct current stimulation be useful in differentiating unresponsive wakefulness syndrome from minimally conscious state patients?", "role": "user" }, { "content": "Is transcranial direct current stimulation effective in distinguishing between unresponsive wakefulness syndrome and minimally conscious state patients?", "role": "assistant" } ]

[ { "content": "Is etoricoxib effective in preventing heterotopic ossification after primary total hip arthroplasty?", "role": "user" }, { "content": "Does etoricoxib prevent heterotopic ossification following primary total hip arthroplasty?", "role": "assistant" } ]

[ { "content": "Assessing Patient Reported Outcomes Measures via Phone Interviews Versus Patient Self-Survey in the Clinic: Are We Measuring the Same Thing?", "role": "user" }, { "content": "Do Phone Interviews and In-Clinic Self-Surveys Yield Comparable Results for Patient Reported Outcomes Measures?", "role": "assistant" } ]

[ { "content": "Can emergency physicians accurately and reliably assess acute vertigo in the emergency department?", "role": "user" }, { "content": "How accurately can emergency physicians diagnose acute vertigo in an emergency department setting?", "role": "assistant" } ]

[ { "content": "Proof of concept study: does fenofibrate have a role in sleep apnoea syndrome?", "role": "user" }, { "content": "Does fenofibrate have therapeutic potential in sleep apnea syndrome?", "role": "assistant" } ]

[ { "content": "Does implant coating with antibacterial-loaded hydrogel reduce bacterial colonization and biofilm formation in vitro?", "role": "user" }, { "content": "Can antibacterial-loaded hydrogel coating on implants decrease in vitro bacterial colonization and biofilm formation?", "role": "assistant" } ]

[ { "content": "Does bone anchor fixation improve the outcome of percutaneous bladder neck suspension in female stress urinary incontinence?", "role": "user" }, { "content": "Does the use of bone anchor fixation enhance the results of percutaneous bladder neck suspension for female stress urinary incontinence?", "role": "assistant" } ]

[ { "content": "Is leptin involved in phagocytic NADPH oxidase overactivity in obesity?", "role": "user" }, { "content": "Does leptin play a role in the overactivity of phagocytic NADPH oxidase in obese individuals?", "role": "assistant" } ]

[ { "content": "Can we predict which head and neck cancer survivors develop fears of recurrence?", "role": "user" }, { "content": "Is it possible to identify head and neck cancer survivors who will develop fears of recurrence?", "role": "assistant" } ]

[ { "content": "Differentiation of nonalcoholic from alcoholic steatohepatitis: are routine laboratory markers useful?", "role": "user" }, { "content": "Are routine lab tests helpful in distinguishing between nonalcoholic and alcoholic steatohepatitis?", "role": "assistant" } ]

[ { "content": "Traumatic aortic injury: does the anatomy of the aortic arch influence aortic trauma severity?", "role": "user" }, { "content": "Does the anatomy of the aortic arch impact the severity of traumatic aortic injury?", "role": "assistant" } ]

[ { "content": "The Prevalence of Incidentally Detected Idiopathic Misty Mesentery on Multidetector Computed Tomography: Can Obesity Be the Triggering Cause?", "role": "user" }, { "content": "Can Obesity Be the Triggering Cause of Incidentally Detected Idiopathic Misty Mesentery on Multidetector Computed Tomography?", "role": "assistant" } ]

[ { "content": "Fast foods - are they a risk factor for asthma?", "role": "user" }, { "content": "Do fast foods contribute to the development of asthma?", "role": "assistant" } ]

[ { "content": "Assessment of appropriate antimicrobial prescribing: do experts agree?", "role": "user" }, { "content": "Do experts concur on the evaluation of proper antimicrobial prescribing?", "role": "assistant" } ]

[ { "content": "Pulmonary valve replacement in adults late after repair of tetralogy of fallot: are we operating too late?", "role": "user" }, { "content": "Are adults undergoing pulmonary valve replacement too late after tetralogy of Fallot repair?", "role": "assistant" } ]

[ { "content": "Is amoxapine an atypical antipsychotic?", "role": "user" }, { "content": "Does amoxapine classify as an atypical antipsychotic?", "role": "assistant" } ]

[ { "content": "Do older patients who refuse to participate in a self-management intervention in the Netherlands differ from older patients who agree to participate?", "role": "user" }, { "content": "What are the differences between older patients in the Netherlands who decline to participate in a self-management intervention and those who agree to participate?", "role": "assistant" } ]

[ { "content": "Is horizontal semicircular canal ocular reflex influenced by otolith organs input?", "role": "user" }, { "content": "Does the otolith organs input affect the horizontal semicircular canal ocular reflex?", "role": "assistant" } ]

[ { "content": "Preoperative tracheobronchoscopy in newborns with esophageal atresia: does it matter?", "role": "user" }, { "content": "Does preoperative tracheobronchoscopy make a difference in newborns with esophageal atresia?", "role": "assistant" } ]

[ { "content": "Is it appropriate to implant kidneys from elderly donors in young recipients?", "role": "user" }, { "content": "Is it acceptable to transplant kidneys from older donors into younger patients?", "role": "assistant" } ]

[ { "content": "Is muscle power related to running speed with changes of direction?", "role": "user" }, { "content": "Does muscle power influence an athlete's running speed when changing direction?", "role": "assistant" } ]

[ { "content": "Stretch-sensitive KCNQ1 mutation A link between genetic and environmental factors in the pathogenesis of atrial fibrillation?", "role": "user" }, { "content": "Does a stretch-sensitive KCNQ1 mutation serve as a link between genetic and environmental factors in the pathogenesis of atrial fibrillation?", "role": "assistant" } ]

[ { "content": "Are pelvic anatomical structures in danger during arthroscopic acetabular labral repair?", "role": "user" }, { "content": "Do pelvic anatomical structures risk damage during arthroscopic acetabular labral repair?", "role": "assistant" } ]

[ { "content": "Is intraoperative neuromonitoring associated with better functional outcome in patients undergoing open TME?", "role": "user" }, { "content": "Does intraoperative neuromonitoring improve functional outcomes for patients undergoing open total mesorectal excision?", "role": "assistant" } ]

[ { "content": "Profiling quality of care: Is there a role for peer review?", "role": "user" }, { "content": "Does peer review have a role in evaluating the quality of care?", "role": "assistant" } ]

[ { "content": "Multidisciplinary decisions in breast cancer: does the patient receive what the team has recommended?", "role": "user" }, { "content": "Does a breast cancer patient receive the treatment recommended by the multidisciplinary team?", "role": "assistant" } ]

[ { "content": "Are performance measurement systems useful?", "role": "user" }, { "content": "Do performance measurement systems serve a purpose?", "role": "assistant" } ]

[ { "content": "The colour of pain: can patients use colour to describe osteoarthritis pain?", "role": "user" }, { "content": "Can colour be used by patients to describe osteoarthritis pain?", "role": "assistant" } ]

[ { "content": "Do mossy fibers release GABA?", "role": "user" }, { "content": "Do mossy fibers secrete the neurotransmitter GABA?", "role": "assistant" } ]

[ { "content": "Is severe macrosomia manifested at 11-14 weeks of gestation?", "role": "user" }, { "content": "Does severe macrosomia appear at 11-14 weeks of pregnancy?", "role": "assistant" } ]

[ { "content": "Visceral adipose tissue area measurement at a single level: can it represent visceral adipose tissue volume?", "role": "user" }, { "content": "Does a single-level measurement of visceral adipose tissue area accurately reflect visceral adipose tissue volume?", "role": "assistant" } ]

[ { "content": "Is an advance care planning model feasible in community palliative care?", "role": "user" }, { "content": "Is advance care planning feasible in a community palliative care setting?", "role": "assistant" } ]

[ { "content": "Do cytokines have any role in epilepsy?", "role": "user" }, { "content": "What is the relationship between cytokines and epilepsy?", "role": "assistant" } ]

[ { "content": "Is expert breast pathology assessment necessary for the management of ductal carcinoma in situ ?", "role": "user" }, { "content": "Is specialized breast pathology evaluation required for the management of ductal carcinoma in situ ?", "role": "assistant" } ]

[ { "content": "Treadmill testing of children who have spina bifida and are ambulatory: does peak oxygen uptake reflect maximum oxygen uptake?", "role": "user" }, { "content": "Does peak oxygen uptake during treadmill testing in ambulatory children with spina bifida accurately reflect their maximum oxygen uptake?", "role": "assistant" } ]

[ { "content": "Subclavian steal syndrome: can the blood pressure difference between arms predict the severity of steal?", "role": "user" }, { "content": "Does the difference in blood pressure between arms correlate with the severity of subclavian steal syndrome?", "role": "assistant" } ]

[ { "content": "Is size-reducing ascending aortoplasty with external reinforcement an option in modern aortic surgery?", "role": "user" }, { "content": "Can size-reducing ascending aortoplasty with external reinforcement be a viable option in contemporary aortic surgery?", "role": "assistant" } ]

[ { "content": "Is digoxin use for cardiovascular disease associated with risk of prostate cancer?", "role": "user" }, { "content": "Does digoxin use in cardiovascular disease increase the risk of developing prostate cancer?", "role": "assistant" } ]

[ { "content": "Screening for gestational diabetes mellitus: are the criteria proposed by the international association of the Diabetes and Pregnancy Study Groups cost-effective?", "role": "user" }, { "content": "Are the criteria proposed by the International Association of the Diabetes and Pregnancy Study Groups for screening gestational diabetes mellitus cost-effective?", "role": "assistant" } ]

[ { "content": "Does a 4 diagram manual enable laypersons to operate the Laryngeal Mask Supreme®?", "role": "user" }, { "content": "Can a 4-diagram manual sufficiently guide non-professionals in using the Laryngeal Mask Supreme?", "role": "assistant" } ]

[ { "content": "Is laparoscopic reoperation for failed antireflux surgery feasible?", "role": "user" }, { "content": "Is reoperation via laparoscopy a viable option for failed antireflux surgery?", "role": "assistant" } ]

[ { "content": "The Omega-3 Index: a new risk factor for death from coronary heart disease?", "role": "user" }, { "content": "Is the Omega-3 Index a new risk factor for coronary heart disease mortality?", "role": "assistant" } ]

[ { "content": "Do cytokine concentrations in pancreatic juice predict the presence of pancreatic diseases?", "role": "user" }, { "content": "Can pancreatic juice cytokine levels indicate pancreatic disease?", "role": "assistant" } ]

[ { "content": "Factors determining the survival of nasopharyngeal carcinoma with lung metastasis alone: does combined modality treatment benefit?", "role": "user" }, { "content": "What are the factors that determine the survival rate of nasopharyngeal carcinoma patients with lung metastasis, and can combined modality treatment improve their chances of survival?", "role": "assistant" } ]

[ { "content": "Is minimally invasive mitral valve repair with artificial chords reproducible and applicable in routine surgery?", "role": "user" }, { "content": "Can artificial chord-based minimally invasive mitral valve repair be consistently replicated in everyday surgical practice?", "role": "assistant" } ]

[ { "content": "Does receipt of hospice care in nursing homes improve the management of pain at the end of life?", "role": "user" }, { "content": "Does hospice care in nursing homes enhance end-of-life pain management?", "role": "assistant" } ]

[ { "content": "Is intensive chemotherapy safe for rural cancer patients?", "role": "user" }, { "content": "Does intensive chemotherapy pose risks for cancer patients in rural areas?", "role": "assistant" } ]

[ { "content": "Is the urinary biomarkers assessment a non-invasive approach to tubular lesions of the solitary kidney?", "role": "user" }, { "content": "Does assessing urinary biomarkers offer a non-invasive method for detecting tubular damage in a solitary kidney?", "role": "assistant" } ]

[ { "content": "Does open access endoscopy close the door to an adequately informed patient?", "role": "user" }, { "content": "Does open access endoscopy limit a patient's access to full information?", "role": "assistant" } ]

[ { "content": "Do viral infections have a role in benign paroxysmal positional vertigo?", "role": "user" }, { "content": "Can viral infections contribute to the development of benign paroxysmal positional vertigo?", "role": "assistant" } ]

[ { "content": "Does reducing spasticity translate into functional benefit?", "role": "user" }, { "content": "Does alleviating spasticity lead to improved functionality?", "role": "assistant" } ]

[ { "content": "Is the Retromandibular Transparotid Approach a Reliable Option for the Surgical Treatment of Condylar Fractures?", "role": "user" }, { "content": "Is the Transparotid Approach a Reliable Option for the Surgical Treatment of Condylar Fractures?", "role": "assistant" } ]

[ { "content": "Do ventricular arrhythmias in athletes subside over time?", "role": "user" }, { "content": "Do ventricular arrhythmias in athletes typically resolve on their own over time?", "role": "assistant" } ]

[ { "content": "Are complex coronary lesions more frequent in patients with diabetes mellitus?", "role": "user" }, { "content": "Do patients with diabetes mellitus have a higher incidence of complex coronary lesions?", "role": "assistant" } ]

[ { "content": "Can dogs prime autistic children for therapy?", "role": "user" }, { "content": "Do dogs help prepare autistic children for therapy?", "role": "assistant" } ]

[ { "content": "Quality of life in lung cancer patients: does socioeconomic status matter?", "role": "user" }, { "content": "Does socioeconomic status impact the quality of life for lung cancer patients?", "role": "assistant" } ]

[ { "content": "Is there a model to teach and practice retroperitoneoscopic nephrectomy?", "role": "user" }, { "content": "What model is available for teaching and practicing retroperitoneoscopic nephrectomy?", "role": "assistant" } ]