Unnamed: 0
int64 0
10.5k
| wt_seq
stringlengths 21
680
| mut_seq
stringlengths 21
680
| ddg
float64 -17.4
17.4
| pdb_id
stringclasses 657
values | mut_info
stringlengths 3
6
| pos
int64 0
484
| fold
int64 0
4
|
|---|---|---|---|---|---|---|---|
10,500 | PLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQALLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN | PLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN | 0.5 | 3FISA | A61P | 35 | 2 |
10,501 | GPWAYIMQGPSESFVDFANRLIKAVEGSDLPPSARAPVIIDCFRQKSQPDIQQLIRTAPSTLTTPGEIIKYVLDRQK | GPWADIMQGPSESFVDFANRLIKAVEGSDLPPSARAPVIIDCFRQKSQPDIQQLIRTAPSTLTTPGEIIKYVLDRQK | -0.34 | 3G1GA | Y155D | 4 | 1 |
10,502 | GPWADIMQGPSESFVDYANRLIKAVEGSDLPPSARAPVIIDCFRQKSQPDIQQLIRTAPSTLTTPGEIIKYVLDRQK | GPWADIMQGPSESFVDFANRLIKAVEGSDLPPSARAPVIIDCFRQKSQPDIQQLIRTAPSTLTTPGEIIKYVLDRQK | 0.74 | 3G1GA | Y167F | 16 | 1 |
10,503 | GPWADIMQGPSESFVDFANRLIKAVEGSDLPPSARAPVIVDCFRQKSQPDIQQLIRTAPSTLTTPGEIIKYVLDRQK | GPWADIMQGPSESFVDFANRLIKAVEGSDLPPSARAPVIIDCFRQKSQPDIQQLIRTAPSTLTTPGEIIKYVLDRQK | 0.17 | 3G1GA | V190I | 39 | 1 |
10,504 | GPWADIMQGPSESFVDFANRLIKAVEGSDLPPSAWAPVIIDCFRQKSQPDIQQLIRTAPSTLTTPGEIIKYVLDRQK | GPWADIMQGPSESFVDFANRLIKAVEGSDLPPSARAPVIIDCFRQKSQPDIQQLIRTAPSTLTTPGEIIKYVLDRQK | -1.32 | 3G1GA | W185R | 34 | 1 |
10,505 | EDIPREPRRIVIHRGSTGLGFNIVGGEGLGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEA | EDIPREPRRIVIHRGSTGLGFNIVGGEGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEA | 3.35 | 3K82A | L334E | 28 | 3 |
10,506 | EDIPREPRRIVIHRGSTGLGFNIVGGEGQGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEA | EDIPREPRRIVIHRGSTGLGFNIVGGEGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEA | 1.68 | 3K82A | Q334E | 28 | 3 |
10,507 | EDIPREPRRIVIHRGSTGLGFNIVGGEGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFRA | EDIPREPRRIVIHRGSTGLGFNIVGGEGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEA | -5.49 | 3K82A | R401E | 95 | 3 |
10,508 | RGLGTARLQLVEFSAFVEPPDAVDSYQRHLFVHISQAPPLESVDVRQIYDKFPEKKGGLRELYDRGPPHAFFLVKFWADLNWGFYGVSSQYESLEHMTLTCSSKVCSFGKQVVEKVETERAQLEDGRFVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQELLLCTAYVFEVSTSERGAQHHIHRLVR | RGLGTARLQLVEFSAFVEPPDAVDSYQRHLFVHISQAPPLESVDVRQIYDKFPEKKGGLRELYDRGPPHAFFLVKFWADLNWGFYGVSSQYESLEHMTLTCSSKVCSFGKQVVEKVETERAQLEDGRFVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQELLLCTAYVFEVSTSERGAQHHIYRLVR | 3.23 | 3L15B | H442Y | 199 | 3 |
10,509 | GEWEIIDIGPFTQNLGKFAVDEENKIGQYGRLTFNKVIGPCMKKTIYENE | GEWEIIDIGPFTQNLGKFAVDEENKIGQYGRLTFNKVIRPCMKKTIYENE | -1.194 | 3MONB | G39R | 38 | 1 |
10,510 | GECEIIDIGPFTQNLGKFAVDEENKIGQYGRLTFNKVIRPCMKKTIYENE | GEWEIIDIGPFTQNLGKFAVDEENKIGQYGRLTFNKVIRPCMKKTIYENE | 2.866 | 3MONB | C3W | 2 | 1 |
10,511 | FKDLNLTDAQKQQIREIMKGQRDQMKRPPLEERRAMHDIIASDTFDKAKAEAQIAKMEEQRKANMLAHMETQNKIYNILTPEQKKQINANFEKRLT | FKDLNLTDAQKQQIREIMKGQRDQMKRPPLEERRAMHDIIASDTFDKAKAEAQIAKMEEQRKANMLAHMETQNKIYNILTPEQKKQFNANFEKRLT | 1.81 | 3O39A | I115F | 86 | 0 |
10,512 | FKDLNLTDAQKQQIREIMKGQRDQMKRPPLEERRAMHDIIASDTFDKAKAEAQIAKMEEQRKANMLAHMETQNKIYNILTPEQKKQLNANFEKRLT | FKDLNLTDAQKQQIREIMKGQRDQMKRPPLEERRAMHDIIASDTFDKAKAEAQIAKMEEQRKANMLAHMETQNKIYNILTPEQKKQFNANFEKRLT | 1.64 | 3O39A | L115F | 86 | 0 |
10,513 | FKDLNLTDAQKQQIREIMKGQRDQMKRPPLEERRAMHDIIASDTFDKAKAEAQIAKMEEQRKANMLALMETQNKIYNILTPEQKKQFNANFEKRLT | FKDLNLTDAQKQQIREIMKGQRDQMKRPPLEERRAMHDIIASDTFDKAKAEAQIAKMEEQRKANMLAHMETQNKIYNILTPEQKKQFNANFEKRLT | 0.58 | 3O39A | L96H | 67 | 0 |
10,514 | FKDPNLTDAQKQQIREIMKGQRDQMKRPPLEERRAMHDIIASDTFDKAKAEAQIAKMEEQRKANMLAHMETQNKIYNILTPEQKKQFNANFEKRLT | FKDLNLTDAQKQQIREIMKGQRDQMKRPPLEERRAMHDIIASDTFDKAKAEAQIAKMEEQRKANMLAHMETQNKIYNILTPEQKKQFNANFEKRLT | 3.25 | 3O39A | P32L | 3 | 0 |
10,515 | FKDLNLTDAQKQQIREIMKGQRDQMKRPPLEERRAMHDIIASDTFDKAKAEAQIAKMEEQRKANMLAHMETLNKIYNILTPEQKKQFNANFEKRLT | FKDLNLTDAQKQQIREIMKGQRDQMKRPPLEERRAMHDIIASDTFDKAKAEAQIAKMEEQRKANMLAHMETQNKIYNILTPEQKKQFNANFEKRLT | 2 | 3O39A | L100Q | 71 | 0 |
10,516 | FKDLNLTDAQKQQIREIMKGLRDQMKRPPLEERRAMHDIIASDTFDKAKAEAQIAKMEEQRKANMLAHMETQNKIYNILTPEQKKQFNANFEKRLT | FKDLNLTDAQKQQIREIMKGQRDQMKRPPLEERRAMHDIIASDTFDKAKAEAQIAKMEEQRKANMLAHMETQNKIYNILTPEQKKQFNANFEKRLT | 0.05 | 3O39A | L49Q | 20 | 0 |
10,517 | SLDETTYERLAEETLDSLAEFFEDLADKPYTFEYYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKD | SLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKD | 1.3 | 3S4MA | Y122D | 33 | 4 |
10,518 | SLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSVVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKD | SLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKD | 2.5 | 3S4MA | V130G | 41 | 4 |
10,519 | SLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQFWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKD | SLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKD | -0.096 | 3S4MA | F154I | 65 | 4 |
10,520 | SLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIRLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKD | SLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKD | 0.693 | 3S4MA | R155W | 66 | 4 |
10,521 | KLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDREVVAMARKLQDVFEMRFAKMP | KLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMP | -2.03 | 3S92A | R395H | 88 | 1 |
10,522 | SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDVVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE | SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE | -0.99 | 4BJXA | V89A | 47 | 4 |
10,523 | FACKTANGTAIPIGGGSANVYVNLAPVVNVGQNLVVDLSTQIFCHNDYPETITDYVTLQRGSAYGGVLSNFSGTVKYSGSSYPFPTTSETPRVVYNSRTDKPWPVALYLTPVSSAGGVAIKAGSLIAVLILRQTNNANSDDFQFVWNIYANNDVVVPT | FACKTANGTAIPIGGGSANVYVNLAPVVNVGQNLVVDLSTQIFCHNDYPETITDYVTLQRGSAYGGVLSNFSGTVKYSGSSYPFPTTSETPRVVYNSRTDKPWPVALYLTPVSSAGGVAIKAGSLIAVLILRQTNNYNSDDFQFVWNIYANNDVVVPT | -0.89 | 4BUQA | A137Y | 136 | 0 |
10,524 | FACKTANGTAIPIGGGSANVYVNLAPVVNVGQNLVVDLSTQIFCHNDAPETITDYVTLQRGSAYGGVLSNFSGTVKYSGSSYPFPTTSETPRVVYNSRTDKPWPVALYLTPVSSAGGVAIKAGSLIAVLILRQTNNYNSDDFQFVWNIYANNDVVVPT | FACKTANGTAIPIGGGSANVYVNLAPVVNVGQNLVVDLSTQIFCHNDYPETITDYVTLQRGSAYGGVLSNFSGTVKYSGSSYPFPTTSETPRVVYNSRTDKPWPVALYLTPVSSAGGVAIKAGSLIAVLILRQTNNYNSDDFQFVWNIYANNDVVVPT | 1.435 | 4BUQA | A48Y | 47 | 0 |
10,525 | EDKCKKVYENYPVSKCQLDNQCNYDCKLDKHARSGECFYDEKRNLQCICDYCEY | EDKCKKVYENYPVSKCQLANQCNYDCKLDKHARSGECFYDEKRNLQCICDYCEY | 0.24 | 4HE7A | D19A | 18 | 1 |
10,526 | EDKCKKVYENYPVSKCQLGNQCNYDCKLDKHARSGECFYDEKRNLQCICDYCEY | EDKCKKVYENYPVSKCQLANQCNYDCKLDKHARSGECFYDEKRNLQCICDYCEY | -0.06 | 4HE7A | G19A | 18 | 1 |
10,527 | EDKCKKVYENYPVSKCQLKNQCNYDCKLDKHARSGECFYDEKRNLQCICDYCEY | EDKCKKVYENYPVSKCQLANQCNYDCKLDKHARSGECFYDEKRNLQCICDYCEY | 0.46 | 4HE7A | K19A | 18 | 1 |
10,528 | ATQPATAETQHIADQVRSQLEEKENKKFPVFKAVSFKSQVVAGTNYFIKVHVGDEDFVHLRVFQSLPWENKPLTLSNYQTNKAKHDELTYF | ATQPATAETQHIADQVRSQLEEKENKKFPVFKAVSFKSQVVAGTNYFIKVHVGDEDFVHLRVFQSLPHENKPLTLSNYQTNKAKHDELTYF | -0.574 | 4N6V0 | W75H | 67 | 1 |
10,529 | ATQPATAETQHIADQVRSQLEEKENKKFGVFKAVSFKSQVVAGTNYFIKVHVGDEDFVHLRVFQSLPHENKPLTLSNYQTNKAKHDELTYF | ATQPATAETQHIADQVRSQLEEKENKKFPVFKAVSFKSQVVAGTNYFIKVHVGDEDFVHLRVFQSLPHENKPLTLSNYQTNKAKHDELTYF | 1.362 | 4N6V0 | G36P | 28 | 1 |
10,530 | ATQPATAETQHIADQVRSQLEEKENKKFPVFKAVSFKSQVVAGTNYFIKVHVGDEDFVHLRVFQSLPHENKSLTLSNYQTNKAKHDELTYF | ATQPATAETQHIADQVRSQLEEKENKKFPVFKAVSFKSQVVAGTNYFIKVHVGDEDFVHLRVFQSLPHENKPLTLSNYQTNKAKHDELTYF | -1.745 | 4N6V0 | S79P | 71 | 1 |
10,531 | NEEWVELGSPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDATKFLVPDHVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVYASQET | NEEWVELGSPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVYASQET | -0.1 | 4WAAA | A65K | 56 | 1 |
10,532 | NEEWVELGSPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTAFLVPDHVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVYASQET | NEEWVELGSPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVYASQET | 2.07 | 4WAAA | A67K | 58 | 1 |
10,533 | NEEWVELGSPSEKTFKQRATFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVYASQET | NEEWVELGSPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVYASQET | 0.44 | 4WAAA | A27R | 18 | 1 |
10,534 | QARPTVIRWSEGGKEVFISGSFNNWSTKIPLIKSHNDFVAILDLPEGEHQYKFFVDGQWTHDPSEPVVTSQLGTINNLIHVK | QARPTVIRWSEGGKEVFISGSFNNWSTKIPLIKSHNDFVAILDLPEGEHQYKFFVDGQWVHDPSEPVVTSQLGTINNLIHVK | 0.71 | 4YEEA | T134V | 59 | 2 |
10,535 | ARPTVFRWTGGGKEVYLSGSFNNWSKLPLTRSQNNFVAILDLPEGEHQYKFFVDGQWVHDPSEPIVTSQLGTVNNIIQVK | ARPTVFRWTGGGKEVYLSGSFNNWSKLPLTRSQNNFVAILDLPEGEHQYKFFVDGQWTHDPSEPIVTSQLGTVNNIIQVK | 0.93 | 4YEFA | V134T | 57 | 3 |
10,536 | FREPRRIVIHRGSTGLGFNIVGGEGGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSFPPWVQQTRV | FREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSFPPWVQQTRV | 1.44 | 5JXBA | G329D | 24 | 2 |
10,537 | FREPRRIVIHRGSTGLGFNIVGGEPGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSFPPWVQQTRV | FREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSFPPWVQQTRV | 1.44 | 5JXBA | P329D | 24 | 2 |
10,538 | RSVASSKLWMLEFSAFLEQQQDPDTYNKHLFVHIGLEAVDIRQIYDKFPEKKGGLKDLFERGPSNAFFLVKFWADLNTNGSSFYGVSSQYESPENMIITCSTKVCSFGKQVVEKVETEYARYENGHYSYRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSASEHGAQHHIHRLVKE | RSVASSKLWMLEFSAFLEQQQDPDTYNKHLFVHIGLEAVDIRQIYDKFPEKKGGLKDLFERGPSNAFFLVKFWADLNTNGSSFYGVSSQYESPENMIITCSTKVCSFGKQVVEKVETEYARYENGHYSYRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSASEHGAQHHIYRLVKE | 2.99 | 5OAQA | H429Y | 198 | 0 |
10,539 | MPLDETNNESYRYLRSVGNTWKFNVEDVHPKMLERLYKKFDTFDLDTDGKMTMDEIMYWPDRMRQLVNATDEQVEKMRAAVHTFFFHKGVDPVNGLKREDWVEANRVFAEAERERERRGEPSLIALLSNAYYDVLDDDGDGTVDVEELKTMMKAFDVPQEAAYTFFQKADTDKTGKLERPELVHLFRKFWMEPYD | MPLDETNNESYRYLRSVGNTWKFNVEDVHPKMLERLYKRFDTFDLDTDGKMTMDEIMYWPDRMRQLVNATDEQVEKMRAAVHTFFFHKGVDPVNGLKREDWVEANRVFAEAERERERRGEPSLIALLSNAYYDVLDDDGDGTVDVEELKTMMKAFDVPQEAAYTFFQKADTDKTGKLERPELVHLFRKFWMEPYD | -0.413 | 5VP3A | K39R | 38 | 4 |
10,540 | MPLDETNNESYRYLRSVGNTWKFNVEDVHPKMLERLYKRFDTFDLDTDGKMTMDEIMYWPDRMRQLVNATDEQVEKMRAAVHTFFFHKGVDPVNGLKREDWVEANRVFAEAERERERRGEPSLIALLGNAYYDVLDDDGDGTVDVEELKTMMKAFDVPQEAAYTFFQKADTDKTGKLERPELVHLFRKFWMEPYD | MPLDETNNESYRYLRSVGNTWKFNVEDVHPKMLERLYKRFDTFDLDTDGKMTMDEIMYWPDRMRQLVNATDEQVEKMRAAVHTFFFHKGVDPVNGLKREDWVEANRVFAEAERERERRGEPSLIALLSNAYYDVLDDDGDGTVDVEELKTMMKAFDVPQEAAYTFFQKADTDKTGKLERPELVHLFRKFWMEPYD | 0.378 | 5VP3A | G128S | 127 | 4 |
10,541 | MPLDETNNESYRYLRSVGNTWKFNVEDVHPKMLERLYKRFDTFDLDTDGKMTMDEIMYWPDRMRQLVNATDEQVEKMRAAVHTFFFHKGVDPVNGLKREDWVEANRVFAEAERERERRGEPSLIALLSNAYYDVLDDDGDGTVDVEELKTMMKAFDVPQEAAYTFFQKADTDKTGKLERPELTHLFRKFWMEPYD | MPLDETNNESYRYLRSVGNTWKFNVEDVHPKMLERLYKRFDTFDLDTDGKMTMDEIMYWPDRMRQLVNATDEQVEKMRAAVHTFFFHKGVDPVNGLKREDWVEANRVFAEAERERERRGEPSLIALLSNAYYDVLDDDGDGTVDVEELKTMMKAFDVPQEAAYTFFQKADTDKTGKLERPELVHLFRKFWMEPYD | -0.354 | 5VP3A | T183V | 182 | 4 |