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In contrast, long-term E 2 treatment resulted in the downregulation of ERα and p44/42 MAP kinase and upregulation of MMP-9 only, but no changes in c-ErbB2.
6
The two groups did not differ significantly regarding disease-free and overall survival, and had similar rates of toxicities.
5
The positive relationship between collision mortality and building size was greatest at large buildings in regions of low urbanization, locally extensive lawns, and low-density structures.
5
There were no differences in abortion-related morbidity or adverse events in abortion procedures performed in an asc versus an office-based setting.
6
The opposite occurred in the non-south, with mandated desegregation positively associated with increases (although small) in the black teaching force.
5
There are also subtle results that demonstrate the equivalence of such apparently different institutions as the standard sealed-bid auction, in which the auctioneer/seller sells the goods to the highest bidder for a price equal to his bid, and the Dutch auction, in which the auctioneer/seller begins by asking a high price and gradually lowers the price until"
5
The data do not support the use of ramucirumab in first-line therapy for patients with gastric or gastroesophageal junction adenocarcinomas.
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The healthy calves were also infected by a related, although less harmful, parasite species: theileria mutans or theileria velifera.
4
The orally administered compound kbu2046 inhibited metastasis, reduced bone destruction, and prolonged survival, without any evident toxicity.
6
The effect of race on the experience of emotional and physical stress symptoms from racism is substantial.
6
Our dynamical results convincingly demonstrate that M67 could not have been the birth cluster of our solar system.«
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CONCLUSIONS:Contrary to popular belief, acute sauna use does not lead to a reduction, but to an increase in BP and HR with a consequent increase in myocardial oxygen consumption.
6
GAT211 did not produce cardinal signs of direct CB 1 -receptor activation in the presence or absence of pathological pain.
6
Even in species capable of perpetuate offspring through cloning, fertilization is still very much required to ensure the survival of the maximum number of healthy offspring, thus indicating that males have not become obsolete just yet.
6
The necessary implication for public policy is that private ownership of a natural resource offers no assurance that the resource will be managed sustainably.
6
There was not enough evidence to provide a guideline based on the grading of recommendation, assessment, development, and evaluation approach.
5
The ratio between the relative risk and benefits of the available therapies for pain in pregnant women, such as NSAIDs and opioids, needs further careful investigation.
2
However, the process cannot be immediate and effortless, and can only be achieved within a market-wide strategic perspective.
6
Non-emitting events occurring during a restricted period are never suspected by a distant observer.
6
Remission was achieved by 54% (56 of 104) and 47% (47 of 99) of the patients given the 400-mg and 1200-mg dosages of rifaximin-EIR, respectively; these rates did not differ from those of placebo.
5
Modern-day rumblings in the new madrid seismic zone are not echoes of the 1811 to 1812 quakes, however.
5
There was evidence that the association was not significantly altered by stage of liver disease or the presence/absence of high alcohol consumption, high body mass index, type 2 diabetes mellitus, smoking, or hepatitis B and C viruses.
6
They have a far more complex structure and composition than previously thought possible.
6
Total fat mass was not significantly different between the 4 beverage groups.
6
Not all of the people buried there grew up locally.
4
Wind and atmospheric turbulence did not significantly impact the system.2 llcd was even able to communicate through thin cirrus clouds.
4
Although Telstar 18’s horizontal range will be nearly 10% shorter than Brazuca’s horizontal range for high-speed kicks, both Telstar 18 and Brazuca have similar knuckling effects due to nearly equal critical speeds and high-speed drag coefficients that differ by less than 10%.
5
In contrast, among controls, those who were depressed rated fewer activities as important, but exhibited few significant differences in the performance of activities.
5
Although active procrastinators procrastinate to the same degree as passive procrastinators, they are more similar to nonprocrastinators than to passive procrastinators in terms of purposive use of time, control of time, self-efficacy belief, coping styles, and outcomes including academic per..."
5
The CeOx layer does not affect the OER activity of the catalyst underneath but exhibits unique permselectivity, allowing the permeation of OH- and O2 through while preventing the diffusion of redox ions through the layer to function as a selective O2 -evolving electrode.
6
No differences in expression of 13 genetic disorders were detected between purebred dogs and mixed-breed dogs (ie, hip dysplasia, hypo- and hyperadrenocorticism, cancers, lens luxation, and patellar luxation).
6
Some declining north american bat species may be able to evolve enough resistance to the disease to persist, while other species appear less likely to do so.
1
The CD4 count was 554 ± 169 cells/μl, and viral load was undetectable in all patients at the time of transplantation.
6
Significant improvements in overall sexual function, most reproductive hormones and in psychological status were maintained over two years following surgery.
6
Preeclampsia is not in fact a single disease caused solely by genetic factors.
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Despite many promising mechanisms to improve the referral process, rigorous evaluations of these improvements are needed.
6
There was no significant between-group difference in the results, except for the papule count at week 4, which was -1.828 and 0.103 on the treated and nontreated sides, respectively.
5
We found few significant changes in leaf traits when vertebrate herbivores were excluded in the short-term.
4
A higher price did not guarantee better performance.
4
Peer comparison letters led to statistically meaningful, persistent decreases in quetiapine prescribing, with no detected negative effects on patients.
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The city continue to explore user engagement sites, among numerous other recommendations, but officials have not committed yet.
5
For the real thing, the locust, slipping is not an anomaly, but part of the dynamic locomotion of the insect.
5
For the entire sample, there were no differences in symptom trajectories between study arms; mean differences in change scores at 12 months were –0.14 (95% confidence interval –0.34 to 0.07) for inattention; –0.13 (–0.31 to 0.05) for hyperactivity/impulsivity; –0.09 (–0.28 to 0.11) for oppositionality; and 3.30 (–1.23 to 7.82) for social skills.
6
The design controlling both sources of bias indicates no impact of ambient scent on the dependent variables.
6
The circadian clock isnat the only clock but rather the main clock in a whole network of internal clocks in the body.
6
Not all video games provide the same benefits to attention.
4
No effect was found in patients with colon and colorectal liver metastases.
6
There was no difference (p=.6) in ease of procedure reported by providers.
6
150 of 2,710 species showed a statistically significant response to four environmental stages.
6
No such changes were seen in their left forearms after cutaneous application of olive oil, rich in oleic acid.
6
The causal assumptions require further prospective or longitudinal studies on the topic.
4
Environmental cues had a very strong influence on daytime sleep behaviors.
6
There was no difference in the activity of the microglia between the two groups.
6
The same is true for how the brain perceives our environment -- it has two distinct systems, one for recognizing a place and another for navigating through it.
6
Two factors were most significantly correlated during the first ten minutes of the postexercise recovery period, when the parasympathetic nervous system (pns) was being reactivated.
6
Mobility levels first declined at the onset of food production, but the transition to a more sedentary lifestyle was gradual, extending through later agricultural intensification.
5
In landscapes where most coffee was grown under the shade of native trees, there was no difference in the number of bat species between shaded (agroforestry) and unshaded coffee.
5
Americans are not alone in having their partisan beliefs occupy a major identity role.
5
Consistent with animal data, we observed early expression of disulfide HMGB1 in patients with newly diagnosed epilepsy, and its persistence was associated with subsequent seizures.
5
The impairing effects of stress and glucocorticoids on retention are not due to disruption of spatial navigation per se.
5
There are still many gaps in our knowledge of effects of climate change on biodiversity.
2
We must pay more attention to this lifestyle factor.
6
In summary, dolutegravir is the first of the second-generation INSTIs and exhibits a predictable pharmacokinetic profile and a well-defined exposure–response relationship.
6
No matter whether more melt-water increases or decreases the speed of ice flow, the effect on sea level is small.
6
Not all neural stem cells respond to the oxygen deficiency.
5
Although HcPCs exhibit a similar transcriptomic profile to bipotential hepatobiliary progenitors, the latter do not give rise to tumors.
6
The presence of the interstellar magnetic field does not influence the overall size or shape of the bow shock.
6
Marijuana is a gateway drug, that it makes one lazy and unproductive, and that marijuana leads to criminal behavior and is bad for the lungs ? well, no, there really is not.
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Hfnc was not inferior to bipap in reintubation rates.
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Pid1 is necessary for cisplatin to be fully effective.
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This difference cannot be blamed solely on genetics, says study coauthor marc hurlbert, executive director of the avon breast cancer crusade.
6
The helmeted woodpecker is actually not closely related to other dryocopus woodpeckers at all and belongs in a different genus, celeus.
6
The music groups had more power and less pain, depression and disability than the control group, but there were no statistically significant differences between the two music interventions.
6
Difficulties and barriers will always be present, but anticipating them will assist in successful implementation of quantitative antimicrobial use (au) feedback and that there is not a one-size-fits-all approach for hospitals or for prescribers.
5
A purposeful delay is not procrastination.
6
The method involved repeated elicitation of choices, and the instructions did not mention a limit on drink size.
5
Seven of 375 (1.9%) of the patients required a repeat ct examination with oral contrast within seven days of their initial scan, although none of these patients required a change in the course of their management following the scan with the oral contrast.
5
Modifying the c-terminus has no significant effect on protein function, and successfully tethers the proteins throughout the hydrogel.
6
We are, however, well aware of the need for caution as advised by Dr Stewart and her colleagues.
5
Although some chemical reactions still go on in the dark, hydrogen cyanide and hydrogen sulphite ions in water only give rise to the building blocks of life when exposed to uv light.
5
Men need to pay more attention to their own health -- and their health-related behaviors -- as they transition into fatherhood.
6
There was no significant group difference in total change in adiposity, but abdominal adiposity decreased more (P = 0.049) in the capsinoid group (−1.11 ± 1.83%) than in the placebo group (−0.18 ± 1.94%), and this change correlated with the change in body weight (r = 0.46, P < 0.0001).
5
There are no long-term emotional costs to aiming high and falling short when it comes to educational aspirations.
6
There was no increase in the motility index in any subject after a drink of hot water.
6