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Retail clinics versus traditional primary care: Employee satisfaction guaranteed?
To examine if differences exist in the levels of autonomy and job satisfaction among primary care nurse practitioners (NPs) employed in retail clinics versus traditional primary care settings.Data were collected from 310 primary care NPs who attended the American Association of NP's 28th Annual Conference in June 2013. Participants completed a demographic form, the Misener NP Job Satisfaction Scale, and the Dempster Practice Behavior Scale.
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Can acute disseminated encephalomyelitis progress in a deferred way?
To report on the heterogeneity with regard to the clinical course of the acute disseminated encephalomyelitis (ADEM).A 5 year old boy suffered of acute disseminated encephalomyelitis of unknown origin. This child suffered two episodes of different neurologic symptoms separated by several weeks. Based on the clinical manifestations and typical appearance of magnetic resonance imaging findings and the absence of oligoclonal bands in CSF immunoglobulins, multiple sclerosis (MS) was ruled out.
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Should pediatric neurosurgeons still manage neurotrauma today?
Neurotrauma remains a major global burden of injury, especially for young patients, and will consequently always be a condition that pediatric neurosurgeons are called upon to treat. However, the face of modern neurotrauma management is changing, presenting important challenges to today's pediatric neurosurgeons.This article summarizes some of the issues in neurotrauma facing clinicians whose responsibility it is to treat these children.
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Can thyroid surgery be decided based on ultrasonographic findings, irrespective of cytopathological findings?
The histopathological findings of resected thyroid lobes were retrospectively reviewed and the findings were compared with the preoperative ultrasonographic and cytopathological findings.The results suggest that the decision to operate on thyroid lesions based on suspicious sonographic findings was correct in a significant number of patients irrespective of the preoperative cytopathological findings.
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Can the composition of the intestinal microbiota predict the development of urinary tract infections?
Fecal samples (n = 40) originated from women with rUTI who received 12 months' prophylaxis of either trimethoprim-sulfamethoxazole (TMP-SMX) or lactobacilli. Microbial composition was assessed by 16S rRNA pyrosequencing.At baseline, fecal microbiota of women with zero and more than or equal to four UTIs during follow-up showed no significant differences. Only TMP-SMX prophylaxis resulted in reduced microbial diversity. Microbial structure of two samples from the same woman showed limited relatedness.
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Physical and psychological stress in a group of Italian caregivers: a new medical emergency?
this study aimed to evaluate physical and psychological stress in a group of italian caregivers.20 subjects were enrolled in the study and divided into 2 groups: 10 healthy controls and 10 caregivers. Every subject underwent an cognitive, clinical and instrumental assessment.the statistical analysis showed an increased presence of pathological alterations in caregivers group such as decreased ejection fraction, cognitive impairment and depressed mood.
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Is there a place for placebo in management of psychogenic movement disorders?
The management of psychogenic movement disorders is fraught with difficulties. Empathy and a non-judgmental manner are essential in dealing with patients, and a neurobiological explanation of the symptoms may help to foster trust, acceptance, understanding and recovery.We report a 17-year-old Chinese girl with psychogenic blepharospasm. Her parents refused psychotherapy and pharmacotherapy.Placebo therapy (with parental consent) was prescribed with favourable results.
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USA endometrial cancer projections to 2030: should we be concerned?
Multivariate linear regression was used to project EC incidence by modeling trends in EC incidence from 1990 to 2013, while accounting for temporal changes in obesity, hysterectomy and smoking.The best-fitting model predicting EC rates included a time effect plus effects for hysterectomy (12-year lag), severe obesity (3-year lag) and smoking (9-year lag). The best-fitting model projected an increase to 42.13 EC cases per 100,000 by the year 2030, a 55% increase over 2010 EC rates.
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Costs of pharmaceutical care: can the profession do anything?
To review some of the factors that influence the cost of pharmaceuticals and the delivery of pharmaceutical care as well as some possible measures for decreasing these costs.Clinical studies have been selected to illustrate factors that may add to the overall cost of pharmaceutical care.
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Are advanced glycation end-product-modified proteins of pathogenetic importance in fibromyalgia?
To quantify the serum levels of the advanced glycation end-product (AGE) pentosidine in 41 patients with fibromyalgia (FM) and 46 healthy controls. The formation of pentosidine is closely related to oxidative stress.Pentosidine was measured by reverse-phased high-performance liquid chromatography with gradient separation on a RP-18 column.Patients with FM have significantly higher pentosidine serum levels than healthy subjects.
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Can roxithromycin and betamethasone induce acute pancreatitis?
Acute pancreatitis has been reported in a few cases treated with macrolides or glucocorticoids.We report the case of a 58 year old patient who, after 2 days of treatment with roxithromycin and betamethasone, manifested acute pancreatitis. Other causes of the disease were ruled out. No re-occurrence of pancreatitis was observed in a 16 month follow-up.
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Biochemical changes in fibromyalgia. Can serum hyaluronic acid be used diagnostically?
Serum levels of HA were determined in 53 patients with established FM and 55 control samples with a radiometric assay (Pharmacia). Values were correlated to clinical parameters of disease severity (duration of disease, tender point scales, visual analogue scales).There were no differences in the HA levels of patients and controls. In all the patients, except one, values were within the reference intervals. Nor was there an association between HA levels and clinical findings.
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Can mutation and selection explain virulence in human P. falciparum infections?
Parasites incur periodic mutations which must ultimately be eliminated to maintain their genetic integrity.It is hypothesised that these mutations are eliminated not by the conventional mechanisms of competition between parasites in different hosts but primarily by competition between parasites within the same infection.This process is enhanced by the production of a large number of parasites within individual infections, and this may significantly contribute to parasitic virulence.
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Relative transcript quantification by quantitative PCR: roughly right or precisely wrong?
When estimating relative transcript abundances by quantitative real-time PCR (Q-PCR) we found that the results can vary dramatically depending on the method chosen for data analysis.Analyses of Q-PCR results from a salmon louse starvation experiment show that, even with apparently good raw data, different analytical approaches 12 may lead to opposing biological conclusions.
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Can chitotriosidase be a surrogate marker for invasive fungal disease?
Chitotriosidase (CHT) enzyme has been known to be secreted from the activated macrophages. We infer with these data that CHT activity is an indicator for the defence.In this study, we evaluated CHT levels in both neutropenic and non neutropenic patients. CHT enzyme activity was measured and compared to each other groups.Chitotriosidase levels were found to be significantly higher in neutropenic patients with candidemia.
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Is diagnostic ultrasound safe?
To describe the potential risk of heating during ultrasound examinations and to report the international consensus on the safety of ultrasound in medicine.Literature on the biological effects of hyperthermia and ultrasound.
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Is there an association between fractures of the cervical spine and first- and second-rib fractures?
To investigate a potential association between cervical spine injury and first- and second-rib fractures.Retrospective review of the radiologic and medical records of 28 consecutive patients admitted to an acute spinal injury unit.A total of 10 (36%) of the patients with cervical spine trauma also had fractures of either the first or second ribs. Eight of these 10 patients had a fracture or fracture-subluxation of the seventh cervical vertebra or the C6/7 segment.
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Is month of birth associated with cataract in later life?
It has been suggested that season of birth might influence the susceptibility to cataract in later life.This hypothesis was investigated using data pooled from two case-control studies carried out in Oxfordshire.RESULTS/
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Are obstetrical personnel required for intraoperative fetal monitoring during nonobstetric surgery?
To determine if the scientific literature supports the practice of electronic monitoring of the fetal heart rate (FHR) during nonobstetric surgery.A search of the literature from 1966 to 1995 was performed using MEDLINE.No fetal hypoxic mortality or morbidity has been documented from nonobstetric surgery without occurrence of a maternal hypoxic complication regardless of the use of FHR monitoring or whether alterations of the FHR occurred.
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Endovascular repair of abdominal aneurysms: Is this the method of choice?
The prevalence of abdominal aneurysms has increased due to the aging population, and endovascular repair has developed into an effective, less invasive treatment.METHODS/Two recent cases at the University of Texas-Houston highlight a variety of clinical considerations that allow informed decision-making regarding optimal treatment of abdominal aneurysms. A thorough discussion of recent data summarizes the current understanding and techniques regarding abdominal aortic aneurysm repair.
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Is conservative management of prenatal and neonatal ovarian cysts justifiable?
To evaluate conservative management of fetal and neonatal ovarian cysts.We followed the progress of 11 fetal and 2 neonatal ovarian cysts.Ten fetal cysts were simple at recognition, but 8 silently became complex by birth, with ovarian loss in 6/11 cases (54%). In 2 cases where large simple cysts presented for the first time at birth, serious complications occurred, resulting in the death of 1 newborn.
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Can beta-blocker therapy be withdrawn from patients with dilated cardiomyopathy?
It has yet to be determined whether withdrawing beta-blocker therapy from patients with dilated cardiomyopathy (DCM) is safe.The influence of tapering and then stopping metoprolol was clarified in 13 patients with DCM who had been receiving this agent for>/=30 months.Seven of the 13 patients deteriorated, including 4 who died suddenly or of congestive heart failure during the 4-month period after metoprolol cessation.
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Acute relapse in Charcot-Marie-Tooth 1B neuropathy: can protein P0 behave like an autoantigen?
The natural history of Charcot-Marie-Tooth neuropathy is marked by accentuated motor and sensitive deficits suggestive of acute polyradiculoneuritis or, more generally, chronic inflammatory demyelinizing polyneuropathy.A 41-year-old woman, with Charcot-Marie-Tooth (CMT) 1B neuropathy associated with a P0 gene mutation, developed several episodes of ataxia which resolved after intravenous administration of IgG or corticosteroids.
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Current trends in the management of radical retropubic prostatectomy: is short-stay RRP feasible in the United Kingdom?
Our aim was to review UK practice in the management of radical retropubic prostatectomy and identify opportunities to reduce LOS to American levels.A survey was conducted of BAUS members regarding LOS and postoperative management.Out of 551 surveys 126 were returned. Mean LOS in the UK is 5.2 days. Opiate analgesia, PCA and postoperative epidural may delay discharge. Diet and mobilization are commenced at 1.7 and 2.1 days, respectively.
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Does the timing of mock embryo transfer trial improve implantation in intracytoplasmic sperm injection cycles?
One-hundred fifty women undergoing their first IVF treatment were included in a prospective randomised study in a University hospital clinic. ETTs were performed either on day 21 of the previous cycle, or on day 6 of the controlled ovarian hyperstimulatin (COH) cycle, or conducted at least two cycles before COH cycle. Clinical pregnancy and implantation rates were compared between the groups.There was no difference between the groups in terms of clinical pregnancy or implantation rates.
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Is neck flexion during a cerebrospinal fluid puncture a potentially hazardous maneuver?
Cerebrospinal fluid puncture (CSFP) is a diagnostically meaningful procedure. We describe an acute tetraplegia in a patient as complication after CSFP.Cervical myelopathy due to posterior os odontoideum subluxation was diagnosed, and an occipitocervical fusion was performed surgically. No significant improvement of the neurological status was observed within the following 3 years.
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Does a hospital formulary influence prescribing practice in an acute medical admissions unit?
A retrospective audit of the case notes, prescription charts and discharge summaries of 150 randomly selected emergency medical admissions over a 4 month period.No patient receiving a non-formulary cardiovascular drug on admission had the choice reviewed in line with formulary recommendations. One third of new cardiovascular medications commenced in hospital were not compliant with formulary recommendations. Decisions about drug therapy were rarely justfied in the written hospital record.
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The unresolved problem of the third molar: would people be better off without it?
Third molars are teeth that have little functional value and a relatively high rate of associated pain and disease. Their value as part of the dentition of modern people is dubious.The authors review the evolution, development, morbidity and treatment of third molars. They assess the value of third molars in the 21st century and describe the risks these teeth pose when they develop in the dentition.
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Are infantile seborrheic and atopic dermatitis clinical variants of the same disease?
The relationship between infantile seborrheic dermatitis (ISD) and infantile atopic dermatitis (IAD) is controversial.Ninety-six children aged 2-12 months diagnosed with atopic dermatitis and a comparable control group of healthy children were evaluated. Demographic data, personal history of ISD and personal or family history of atopy was considered in both groups.A personal history of ISD was found in 49% of IAD cases and in 17% of controls (P<0.05).
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Are national guidelines for total hip replacement in the UK reflected in practice?
A cross-sectional study was performed to compare the practice of total hip replacement (THR) in the UK against national guidelines.A postal questionnaire was sent to all fellows of the British Orthopaedic Association.Of the 1587 questionnaires sent out, 966 (60.9%) were returned. Of these, 706 (73.1%) were available for data collection and analysis.
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Do the pictures influence scores on the Dartmouth COOP Charts?
To determine the effect of illustrations on COOP Chart responses.Randomized split-half design of 177 patients discharged from a medical centre during a 3 month interval. Patient responses were obtained. However, there are benefits from the use of illustrations. Further research measures. Demographic characteristics and health status.No response differences were observed between patients who received COOP Chart illustrations and those who did not receive illustrations.
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Does acute loss of vision in autosomal dominant optic atrophy occur early in childhood?
In contrast to Autosomal dominant optic atrophy (ADOA), acute loss of vision is normally observed in Leber's hereditary optic neuropathy (LHON) patients. We present a case of a young child with ADOA with a confirmed OPA1 mutation who appeared to have had an acute visual loss in the third year of life.Differentiating between ADOA and LHON requires careful documentation of visual symptoms, family history, clinical examination and genetic testing if available.
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Drug-induced acute pancreatitis in children receiving chemotherapy for acute leukemia: does propofol increase the risk?
The use of propofol is controversial in patients with a history of acute pancreatitis or those taking drugs, including certain chemotherapeutic drugs, that are associated with pancreatitis.To investigate this issue, we reviewed the medical records of all children who were diagnosed with pancreatitis while receiving chemotherapy for acute leukemia during a 5-year period.A temporal relationship between propofol use and development of acute pancreatitis could not be established.
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Do health factors affect memory performance in old age?
The aim of this study was to examine the effect of health factors on memory performance in a population-based sample of 679 older people (mean age=69.2 years).Both subjective and objective indices of health were used as predictor variables. Memory performance was measured with an immediate recall test and a delayed recall test.Some of the objective health indices were correlated with performance on the memory tasks, but regression analysis showed that they hardly had a unique effect on memory performance.
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Is tibiofemoral osteoarthritis in the knee joint a new disease?
To compare the prevalence of osteoarthritis (OA) of the hip, tibiofemoral and patellofemoral joints in a skeletal population.A total of 785 adult English skeletons (695 Saxon or Mediaeval origin) were examined for OA using established criteria.Twenty nine skeletons had hip OA, compared with 14 with patellofemoral joint OA, and only four tibiofemoral joint OA.
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Anti-GM1 antibodies: the cause of otherwise unexplained ophthalmoplegias?
To report four patients with otherwise unexplained ophthalmoplegia who were found to have elevated levels of anti-GM1 antibodies.Retrospective chart evaluation of 50 consecutive patients with otherwise unexplained ophthalmoparesis. All patients were tested for anti-GM1 antibodies.Six out of 50 cases (12%) were found to have elevated anti-GM1 antibodies, far greater than the 2.7% found in the general population. Four of the subjects with elevated anti-GM1 antibodies are reported.
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Myopic strabismus fixus: a mitochondrial myopathy?
Ultrastructural analysis of extraocular muscle in a case of myopic strabismus fixus.Interventional case report.Incisional biopsy and ultrastuctural analysis of recti muscles in a female patient with myopic strabismus fixus.Ultrastuctural analysis revealed evidence of mitochondrial myopathy.
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Is long-term adjuvant treatment of breast cancer with anastrozole indicated?
Tamoxifen is the established adjuvant treatment for postmenopausal women with hormone-sensitive breast cancer.To determine whether the aromatase inhibitor anastrozole should replace tamoxifen as the adjuvant treatment in this cancer.Two recent trials of anastrozole and tamoxifen as adjuvant treatment were evaluated.RESULTS/
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Is recurrent loss of low frequency tone perception--without vertigo--a precursor of Meniere disease?
Recurrent low-frequency sensory hearing loss is one characteristic sign of Meniere's disease. It is therefore often assumed to be a prodromal sign of Meniere's disease.We report on 81 patients with recurrent low-frequency sensory hearing loss who did not previously suffer from vertigo. All patients underwent a follow-up examination after at least 1 year up to more than 10 years after the onset of the disease [average: 64.65 months (SD 56.33)].
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Are bilateral fetal lung masses double trouble?
To examine the perinatal natural history of bilateral fetal cystic lung masses.The records of a tertiary medical center over a 3-year period were reviewed for cases of fetal bilateral pulmonary masses.Three of 98 fetuses referred for evaluation over a 3-year period from September of 1995 to August of 1998 had bilateral lung lesions. Two of these cases resulted in live births, while one, associated with hydrops, resulted in death after preterm delivery.
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Sperm count. Do we need a new reference value?
To evaluate the sperm count in fertile men, general population, and infertile men in different regions of the world.Sperm counts were recorded according to their fertility status, proven fertility, men recruited from an andrology/infertility clinic, or healthy men.The average of sperm count in the different studies is lower in infertile men that in fertile men (p>0.001) and in the general population (p>0.001).
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Snakebite in a child: could we avoid the anaphylaxis or the fasciotomies?
We report the unusual presentation and complications of a case of snakebite, involving a child and his mother, who were bitten by the same snake.The mother was well but the child developed worsening local pain and swelling.Test doses of antivenom were administered but he developed anaphylactic shock. Subsequently, he developed compartment syndrome and fasciotomies were performed.
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Change blindness in children with ADHD: a selective impairment in visual search?
This study evaluated change blindness and visual search efficiency in children with ADHD in searching for central and marginal changes.A total of 36 drug-naïve children (18 ADHD/18 controls) performed a flicker task that included changes in objects of central or marginal interest. The task required observers to search for a change until they detected it.Children with ADHD performed more slowly and less accurately than did typically developing children, specifically in detecting marginal-interest changes.
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Is the dorsal percutaneous approach well-founded for osteosynthesis of scaphoid fractures?
To compare complications associated with dorsal percutaneous and limited dorsal approaches in the surgical treatment of fractured scaphoid bone.A total of 51 patients with acute type A2, B2 and B3 scaphoid fractures were treated by limited dorsal approach. During follow-up examinations we analysed the functional outcome and per- and post-operative complications, and we compared them with studies using the dorsal percutaneous approach.We found fewer complications using the limited dorsal approach.
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Do patients with schizophrenia consciously recollect emotional events better than neutral events?
The influence of the emotional valence of words on conscious awareness was assessed in patients with schizophrenia.The remember/know procedure was used to test 24 patients with schizophrenia and 24 normal comparison subjects.Patients' "remember" responses and conscious recollection were more frequent for emotional words than for neutral words. In contrast, the levels of "know" responses and familiarity were independent of emotional words.
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Does the use of hydrochloric acid damage silicone rubber central venous catheters?
Hydrochloric acid (HCl) is commonly used to clear obstructions in central venous catheters (CVC).To determine if HCl adversely affects the integrity of a CVC we infused 0.1 N HCl daily into CVC in vitro. At weekly intervals sections of the CVC were removed and examined using scanning electron microscopy.Over 8 weeks, no damage to the CVC was visible.
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Acute proptosis in trauma: retrobulbar hemorrhage or orbital compartment syndrome--does it really matter?
To review the nature and outcomes of acute severe proptosis in patients after craniofacial trauma, over a 6-year period.These were identified prospectively. The mechanism of injury, nature of the proptosis, and visual outcomes in each case were reviewed. Review of the literature was undertaken.In all cases proptosis, was secondary to retrobulbar edema and not hemorrhage.
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Are nondrinkers missing from the picture?
WHO statistics indicate that half the world's population does not drink alcohol. With a Western outlook this fact is often overlooked.The article explores the global drinking patterns focusing on non-drinking and the global forces that contribute towards change. The large segment of non-drinking population is beneficial for public health but it is also seen as a great potential for the international alcoholic beverage industry.
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Does the nuchal cord persist?
Ultrasound was done on 200 consecutive pregnant women and nuchal cord was documented at 18-20, 30-32 and 36-38 weeks' gestation.The incidence of nuchal cord was 6% at 18-20 weeks, 7.5% at 30-32 weeks, 26.5% at 36-38 weeks and 28% at birth. The persistence of nuchal cord was 8.3% from 18 to 20 to 30-32 weeks, 26.6% from 30-32 to 36-38 weeks and 84.9% from 36-38 weeks to delivery. Using the Friedman test, the change in the presence of nuchal cord was significant (P<0.001).
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Does surgical subspecialization in pediatrics provide high-quality, cost-effective patient care?
To determine if pediatric surgical subspecialization provides cost-effective, high-quality pediatric patient care.Ureteroneocystostomy inpatients over 4 years were studied. Hospital charges and complications were compared between general urologists and fellowship-trained pediatric urologists.Hospital charges were significantly less ($1095) for patients under the care of a pediatric urologist. Complication rates were also lower.
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Addressing mental health concerns in schools: does School-Link achieve its aims?
The aim of this paper was to evaluate the reach and impact of the New South Wales' School-Link initiative.Postal surveys, focus groups and interviews were conducted.School-Link has established a strong partnership between health and education, raised the awareness of child and adolescent mental health problems and contributed in the areas of prevention and early intervention.
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Do clozapine and risperidone affect social competence and problem solving?
The purpose of this investigation was to evaluate the effects of clozapine and risperidone on social skill and problem solving in patients with schizophrenia.The Wisconsin Card Sorting Test and the Maryland Assessment of Social Competence were administered at baseline, week 17, and week 29 of a multisite clinical trial.Despite evidence of clinical improvement with both medications, there was virtually no medication effect on either social competence or problem solving.
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Do clinical safety charts improve paramedic key performance indicator results?
Is the Clinical Safety Chart clinical improvement programme (CIP) effective at improving paramedic key performance indicator (KPI) results within the Ambulance Service of New South Wales?The CIP intervention area was compared with the non-intervention area in order to determine whether there was a statistically significant improvement in KPI results.The CIP was associated with a statistically significant improvement in paramedic KPI results within the intervention area.
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Is the implantation of titanium stems in hip prostheses really obsolete?
Studies between 1960 and July 2002 were analysed concerning failure rates of cemented titanium total hip arthroplasties regarding their specific implant characteristics.Specific implant characteristics such as roughness of the surface and geometrical features led to significantly different failure rates. Stems of titanium with a dull surface and a wide proximal geometry could achieve such good results as those of the cobalt-chromium stems published in the study results of Malchau.
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Is the lack of concurrence of bacterial vaginosis and vaginal candidosis explained by the presence of bacterial amines?
We report for the first time an inhibitory effect on cell division and germ tube formation by Candida albicans and strains of other Candida species by putrescine and cadaverine.Both bacterial amines showed a dose-dependent inhibition of germ tube formation by C albicans, as well as budding (inhibition of cell division) of strains of other Candida species (ie, C glabrata, C krusei, and C tropicalis).
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Are the El Escorial and Revised El Escorial criteria for ALS reproducible?
For accurate diagnosis, inter-observer agreement of criteria is important.Using case records, the reproducibility of the original and revised El Escorial diagnostic criteria for amyotrophic lateral sclerosis were tested in a consecutive series of people referred to the Scottish Motor Neuron Disease Register.Agreement between independent observers was similar (weighted kappa: 0.783, 95% CI 0.656 to 0.911 (original criteria), 0.681, 95% CI 0.485 to 0.878 (revised)).
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Multiple follicular cysts, infundibular type with vellus hairs and solar elastosis of the ears: a new dermatoheliosis?
Vellus hair cyst is an uncommon developmental abnormality of the vellus follicle histologically defined as a stratified squamous epithelial-lined cyst containing one or more vellus hairs.Herein, we report three patients with a heretofore described clinicopathologic condition consisting of multiple contiguous cysts of the ear helices showing solar elastosis and multiple cysts containing vellus hairs, microscopically.
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Is endometrial infection with Candida albicans a cause of recurrent vaginal thrush?
It was hypothesised that the endometrium might act as a reservoir for candida, thus infecting the vagina as the endometrium is shed during menstruation.A prospective study of women with recurrent vulvo-vaginal candidiasis. The endometrium was sampled and cultured for candida species.Central London STD clinic.26 women were enrolled, of whom 20 completed the study.One patient had a positive endometrial culture for candida species, the isolate being Candida krusei.
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Methodologists and their methods. Do methodologists write up their conference presentations or is it just 15 minutes of fame?
To assess the extent to which abstracts of methodological research, initially presented at meetings on systematic reviews, have gone on to be published as full articles.Full publication was assessed in three ways: a search was carried out of The Cochrane Library; a search was conducted using MEDLINE; and a questionnaire was sent to the contact author of each abstract.Approximately half of the abstracts had not been, or were unlikely ever to be, published in full.
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Do German World War II victims fulfill PTSD-criteria?
Long-term psychiatric consequences of World War II are currently a main medical and political topic in Germany.This retrospective study examined 33 psychogeriatric cases.PTSD-criteria following ICD-10 were fulfilled in every case. All patients had a delayed subtype of PTSD with a latency of 14-60 years between trauma and onset of disorder. No case of chronic PTSD was found. In 26 cases a depression was diagnosed.
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Emotional disorders in the working population: an emerging problem in occupational health?
To know the prevalence of emotional disorders in a working population.Workers in four companies: construction (A), automobile components (B), electrical and electronic systems (C) and management services (D). The design of the study was cross-sectional with the GHQ-28 questionnaire.The prevalence fluctuated between 8,4% (A) and 24,0% (D). Sex, age, educational level and occupation showed significance differences in some companies.
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Tearing and eyelid laxity with no ectropion: is tarsal strip always effective?
To verify whether the tarsal strip procedure improves epiphora of patients with eyelid laxity but no ectropion.A retrospective study was done with a sample of epiphora patients with lax eyelids in normal position and no nasolacrimal obstruction who were operated on with the tarsal strip technique. Fourteen lower eyelids, in 11 patients, were included in the study.Epiphora in ten eyes (71.4%) completely or significantly improved after a follow-up of three months. Eyelid laxity disappeared in all cases.
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HLA-DR4 and career prospects in rheumatology: is there a link?
To determine whether HLA type is associated with career progress in rheumatology.Comparison of HLA type after HLA analysis of samples of venous blood.Department of Rheumatology Research, University of Birmingham.All (37) staff in the department.All the senior academics and most staff with a PhD expressed HLA-DR4. The prevalence of expression in each of these groups was significantly greater than that found in the controls. None of the junior doctors or secretaries expressed DR4.
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Can keratinocytes cause failure of osseointegration?
Attached tissue from the explanted or removed titanium implants was examined by transmission electron microscopy and histopathological analysis.Attached tissue from both implants showed the presence of keratinocytes at the titanium implant and living bone interface. This was confirmed by histopathological analysis. In one case, there was frank keratinocyte proliferation, which had led to osseointegration failure; in the other case, such proliferation was present but not so advanced.
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Diagnosing Tourette syndrome: is it a common disorder?
The evaluate the prevalence of Tourette syndrome (TS).A review of the literature on TS was undertaken to examine the prevalence of TS in mainstream children as well as those in special education.Recent studies have indicated that TS occurs in around 1% of youngsters in mainstream schools between the ages of 5 and 16 years. It is even more common in youngsters with special educational needs.
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Limb deformity in a newborn. Is rifampicin just an innocent bystander?
The first-line antituberculous agents for use during pregnancy have minimal teratogenic effects. The possibility of limb deformity during rifampin use, however, was reported by some researchers.A male newborn was born with a hypoplastic right forearm to a mother with tuberculosis who used isoniazid and rifampicin in the first two months of her pregnancy.
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Clinical guidelines for dentistry: will they be useful?
To review the literature on the development and effectiveness of clinical guidelines.Literature review of relevant publications following a Medline search. Publications that reported studies investigating effectiveness of guidelines were confined to randomised controlled trials.
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Is laparoscopic donor nephrectomy here to stay?
Open live donor nephrectomy is safe and provides kidneys of excellent quality. The complexity of the laparoscopic donor technique has raised considerable concerns.Twenty-six laparoscopic live donor nephrectomies were done from October 1997 to October 1998.All kidneys had immediate function. All recipients except 1 had serum creatinines less than 2.0 mg at 2 months posttransplantation. Three complications (wound infection, neuroma, reoperation) occurred. There was no mortality.
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Do wrist guards have the potential to protect against wrist injuries in bicycling, micro scooter riding, and monkey bar play?
To test the potential of wrist guards to prevent wrist injury in recreational activities that require good grip strength and hand dexterity.Forty eight children aged 5-8 years from one Melbourne school volunteered for tests chosen or devised following a review of the literature on the effects of orthoses use and hand function.Wrist guard wearing significantly degraded grip strength, bicycle steering, and performance on a monkey bar. Micro scooter steering was not significantly affected by their use.
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Are there gender related differences in neonatal abstinence syndrome following exposure to buprenorphine during pregnancy?
A retrospective cohort study was performed in which maternal and infant data were collected for 46 male and 44 female infants. All infants were born to women enrolled in a buprenorphine treatment program from December 2007 until October 2012. Maternal and infant characteristics and outcomes were compared by infant gender.Male infants had a significantly higher mean peak NAS score (10.04 vs. 7.98, P=0.028) and were more likely to require pharmacologic treatment for NAS (39.1% vs. 11.4%, P=0.005).
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Is dedicated chest CT needed in addition to PET/CT for evaluation of pediatric oncology patients?
To assess the computed tomography (CT) portion of a positron emission tomography (PET)/CT, at lower dose without breath holding, as compared to diagnostic chest CT (dCTC), performed at regular dose with breath holding, and question the necessity of both for patient care in pediatric oncology.This retrospective study included 46 pediatric patients with histologically proven malignant tumors that had a total of 119 scans.A total of 29 discrepancies were found between dCTC and PET/CT reports.
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Is the open-mouth odontoid view necessary in children under 5 years?
Questionnaires (984) were submitted to pediatric radiologists to determine how often odontoid fractures were missed on lateral views and detected on open-mouth odontoid views in children under 5 years. Other questions relating to imaging protocols of the odontoid also were included, and there were 432 respondents.Of these, 161 respondents indicated that an open-mouth odontoid view was not routinely included in their imaging protocol.
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Fetal short time variation during labor: a non-invasive alternative to fetal scalp pH measurements?
To determine whether short time variation (STV) of fetal heart beat correlates with scalp pH measurements during labor.From 1279 deliveries, 197 women had at least one fetal scalp pH measurement. Using the CTG-Player, STVs were calculated from the electronically saved cardiotocography (CTG) traces and related to the fetal scalp pH measurements.There was no correlation between STV and fetal scalp pH measurements (r=-0.0592).
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Is joint hypermobility associated with vesico-ureteral reflux?
To assess whether there is an increased prevalence of joint hypermobility in patients with vesico-ureteric reflux (VUR).We studied 50 patients with primary VUR and matched controls drawn from a reference population. Joint mobility was assessed using the Bulbena hypermobility score.We identified significantly more patients with VUR with generalized joint hypermobility than controls (24% vs 6.7%, P= 0.007).
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Does sampling site influence levels of free thyroxine and thyrotropin determined by a current immunoassay?
To examine the effect of sampling site on levels of free thyroxine (fT4) and thyrotropin (TSH).fT4 and TSH were determined by a current immuno-assay in paired samples of capillary and venous blood drawn from 30 euthyroid adults.Mean levels of fT4 and TSH did not differ significantly between capillary and venous blood; capillary and venous levels correlated well and did not differ significantly from unity.
pubmed
Is collectionism a diagnostic clue for Diogenes syndrome?
Diogenes syndrome (DS) is characterized by extreme self-neglect, domestic squalor, and social withdrawal. Despite having been described decades ago, it is still difficult to persue a correct diagnosis in primary care clinics.This paper reports a case of an elderly man with extreme self neglect and an abnormal collecting pattern whose condition remained undetected for many years. His collectionism was manifested with a tendency to store items in an organized manner but without a clear purpose.
pubmed
Strength analysis of 6 resorbable implant systems: does heating affect the stress-strain curve?
The objective was to directly compare the strength of 6 different resorbable implant plating systems using an in vitro model before and after heating.Red oak wood was cut and fixated using various resorbable plates and screws. Vertical load was applied and the specimens fractured, while a test machine gathered data. This was repeated after heating of the specimens.Several parameters were analyzed, and force versus displacement curves were plotted for each specimen.
pubmed
Solitary pulmonary nodule in a patient with treated carcinoma of the renal pelvis: metastatic disease?
To describe a case of a solitary pulmonary nodule in a patient that had been treated for carcinoma of the renal pelvis.A solitary pulmonary nodule was detected on the chest film of a patient that had been treated for carcinoma of the renal pelvis. The characteristics of the nodule are described and its diagnosis, with special reference to metastasis and primary pulmonary carcinoma, is discussed.The anatomopathological study demonstrated a chondroid hamartoma.
pubmed
Is there a relationship between attention deficit/hyperactivity disorder and Osgood-Schlatter disease?
The purpose of this prospective study is to investigate the relationship between Osgood-Schlatter disease (OSD) and attention deficit/hyperactivity disorder (ADHD).Seventy-four children with a diagnosis of OSD were referred to child and adolescent psychiatry department for the evaluation of ADHD. Diagnostic and Statistical Manual of Mental Disorders was used for diagnostic criteria.Diagnosis of ADHD was made in 56 (75.6 %) out of 74 children.
pubmed
Are older people prescribed antidepressants on the basis of fewer symptoms of depression, and for longer periods of time?
An online survey about experiences with, and opinions about, depression and antidepressants was completed by 1825 New Zealand adults who had been prescribed antidepressants in the preceding five years.Participants over 55 were prescribed antidepressants with significantly fewer symptoms and were significantly less likely to meet DSM criteria for depression. They were also significantly more likely to have used the drugs for three years and still be using them.
pubmed
Does extracorporeal shock wave lithotripsy cause hearing impairment?
To evaluate if multiple sessions of extracorporeal shock wave lithotripsy (ESWL) have any effect on the transient evoked otoacoustic emissions (TEOAEs).Prospective study.Academic tertiary medical centre.Thirty patients undergoing multiple sessions of ESWL for urinary stone disease were assessed using TEOAEs before and after ESWL.It was found that ESWL does not cause any significant changes in TEOAEs.
pubmed
ICD and neuromodulation devices: is peaceful coexistence possible?
We present two cases of patients with an IND who underwent ICD implantation and one case of a patient implanted with a biventricular ICD who received an IND 6 months later. Two of these patients had a spinal cord stimulator (SCS), while the other had a sacral neuromodulator.No cross-talk was recorded in the patient with the sacral neuromodulator and the ICD. Temporary damage to one of the SCSs was observed after multiple ICD shocks.
pubmed
The association between cognition and functional outcome in first-episode patients with schizophrenia: mystery resolved?
The presence of a prospective association between cognition and functional outcome in first episode patients with schizophrenia is much debated.Associations between Intelligence Quotient (IQ) measures and functional outcome were assessed at the first hospitalization and after 10 years follow-up.Functional outcome was associated with estimated premorbid IQ and IQ at 10-year follow-up, but not with IQ assessed at first hospitalization.
pubmed
Tobacco education: have New Zealand primary schools done their homework?
To describe the content, delivery and evaluation of tobacco-related (smoke-free) education to pre-teen students and to compare this education with current best practice.Postal survey to staff of 136 New Zealand (NZ) schools with primary-aged children.More than 90% of schools offered some form of education about the harmful effects of tobacco use and many relied on external providers for this education.
pubmed
Can a precise vesiculectomy be performed during radical prostatectomy?
To define the anatomical landmarks allowing precise vesiculectomy to be performed during radical prostatectomy for cancer.12 non-formalin-preserved anatomical subjects were dissected as during retropubic and perineal prostatectomy, with and without coloured latex vascular injection.Three anatomical landmarks were defined: 1) Denonvilliers' fascia; 2) vas deferens; 3) arteries supplying the seminal vesicles.
pubmed
Left hepatic vein: can be sutured and ligated blindly in left hepatectomy?
To determine whether the anatomic characteristics of the left hepatic vein, middle hepatic vein and common trunk could influence the operation procedures of left hepatectomy.Fifteen fresh human liver specimens were dissected and their anatomic characteristics were recorded.The left hepatic vein and middle hepatic vein formed the common trunk of 1.2+/-0.4 cm in length in the 15 liver specimens. The angle between the left hepatic vein and middle hepatic vein was 91+/-18.3 degree.
pubmed
MYH9 syndrome and auto-immune haemolytic anaemia: an unrelated association?
The MYH9 syndrome is a group of rare autosomal dominant platelet disorders associating in most of the cases a macrothrombocytopenia and characteristic leukocyte inclusions. Clinical features may include renal, visual, or hearing impairment. The bleeding tendency is usually moderate.We report a 28-year-old-man, with an auto-immune haemolytic anaemia associated with a MYH9 syndrome.
pubmed
Rate of liver volume increase: can it predict recipient prognosis after left lobe transplantation from living related donors?
The purpose of this study was to determine whether liver volume increase can predict recipient outcome.Size-matched left lobe transplantation was performed for 16 patients. Computed tomography was performed in Week 1 after transplantation. Rate of liver volume increase was compared between survivors and deceased subjects.Mean rate of liver volume increase was significantly higher for survivors than for fatalities.
pubmed
Is histological examination necessary when excising a pilonidal cyst?
Pilonidal disease is a common inflammatory condition mostly affecting young males. Malignant degeneration of a pilonidal cyst is rare, with incidence estimated at 0.1%. The most common type is squamous cell carcinoma and the treatment of choice remains en block resection of the lesion.We present the case of a patient with locally advanced squamous cell carcinoma arising in a pilonidal cyst, due to misdiagnosis of the disease during his first treatment.
pubmed
Is the incidence of elbow osteoarthritis underestimated?
Osteoarthritis is uncommon at the elbow in contemporary populations. We sought to determine whether this was also the case in medieval and premodern times.Standard criteria for osteoarthritis were applied to 496 complete elbows from a necropolis in Provence, France.Osteoarthritis was found in 27% of elbows. Significant differences were noted across periods and age groups but not between the right and left sides.
pubmed
A comparison of radial and axial flux structures in electrical machines
Evaluating radial, axial and transverse flux topologies for 'in-wheel' motor
specter_train_triples
Duplication of chromosome band 12q24.11q24.23 results in apparent Noonan syndrome.
Germline gain-of-function mutations in RAF1 cause Noonan syndrome
specter_train_triples
Gorilla: A Fast, Scalable, In-Memory Time Series Database
Finding surprising patterns in a time series database in linear time and space
specter_train_triples
Scaled Conjugate Gradient Based Adaptive ANN Control for SVM-DTC Induction Motor Drive
Direct torque control of induction machines using space vector modulation
specter_train_triples
Capturing Planned Protests from Open Source Indicators
'Beating the news' with EMBERS: forecasting civil unrest using open source indicators
specter_train_triples
Rogowski current sensor design and analysis based on printed circuit boards (PCB)
Current Sensing Techniques: A Review
specter_train_triples
Blockchain for smart grid resilience: Exchanging distributed energy at speed, scale and security
Blockchains for decentralized optimization of energy resources in microgrid networks
specter_train_triples
An 8$\,\times\,$ 8 Butler Matrix in 0.13-$\mu{\hbox {m}}$ CMOS for 5–6-GHz Multibeam Applications
Novel Design of a 2.5-GHz Fully Integrated CMOS Butler Matrix for Smart-Antenna Systems
specter_train_triples
Design and Fabrication of a Six Degree-of-Freedom Open Source Hand
Open-source, affordable, modular, light-weight, underactuated robot hands
specter_train_triples
Cutaneous leishmaniasis: new dermoscopic findings.
Dermoscopy of cutaneous leishmaniasis
specter_train_triples