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CADS: A Comprehensive Anatomical Dataset and Segmentation for Whole-Body Anatomy in Computed Tomography

Overview

CADS is a robust, fully automated framework for segmenting 167 anatomical structures in Computed Tomography (CT), spanning from head to knee regions across diverse anatomical systems.

The framework consists of two main components:

  1. CADS-dataset:

    • 22,022 CT volumes with complete annotations for 167 anatomical structures.
    • Most extensive whole-body CT dataset, exceeding current collections in both scale (18x more CT scans) and anatomical coverage (60% more distinct targets).
    • Data collected from publicly available datasets and private hospital data, spanning 100+ imaging centers across 16 countries.
    • Diverse coverage of clinical variability, protocols, and pathological conditions.
    • Built through an automated pipeline with pseudo-labeling and unsupervised quality control.
  2. CADS-model:

    • An open-source model suite for automated whole-body segmentation.
    • Performance validated on both public challenges and real-world hospital cohorts.
    • Available as Python script run (this GitHub repo) for flexible command-line usage.
    • Also available as a user-friendly 3D Slicer plugin with UI interface, simple installation and one-click inference.
This repository hosts the CADS-dataset, providing both original CT images and corresponding segmentation masks in their native spacing formats.

For more information on the dataset (data collection, labeling procedures, and model derivatives etc.), please refer to the CADS paper preprint.

Useful Links

Format

All images and segmentations are provided in NIfTI format, organized by data source.

The directory structure is as follows:

root/
├── dataset_name/
│   ├── images/         # Original CT volumes
│   ├── segmentations/  # Segmentation masks (indexing see [model labelmap](https://github.com/murong-xu/CADS/blob/main/resources/info/labelmap.md))
│   └── README.md       # Dataset license, citation, and further details

Important Notice

  • We are not the original owners of the CT images, except for the BrainCT-1mm and CT-TRI datasets newly released in this project.
  • Users should review the corresponding README.md file in each dataset subdirectory before using the data and decide whether to include or exclude that dataset based on their intended use.

Dataset Sources Overview

The CADS-dataset comprises multiple publicly available and private-source datasets, each released under its own license.

The table below summarizes all included sources:

Directory Name Dataset Name License Number of CT Volumes Details
0001_visceral_gc VISCERAL Gold Corpus TBD 40 readme
0002_visceral_sc VISCERAL Silver Corpus TBD 127 readme
0003_kits21 The Kidney and Kidney Tumor Segmentation Challenge (KiTS21) CC BY-NC-SA 4.0 300 readme
0004_lits Liver Tumor Segmentation Benchmark (LiTS) CC BY-NC-SA 4.0 201 readme
0005_bcv_abdomen MICCAI Multi-Atlas Labeling Beyond the Cranial Vault (Abdomen) CC BY 4.0 50 readme
0006_bcv_cervix MICCAI Multi-Atlas Labeling Beyond the Cranial Vault (Cervix) CC BY 4.0 50 readme
0007_chaos CHAOS – Combined (CT-MR) Healthy Abdominal Organ Segmentation Challenge (CT Subset) CC BY-NC-SA 4.0 40 readme
0008_ctorg CT-ORG: Multiple Organ Segmentation in CT CC BY 3.0 140 readme
0009_abdomenct1k AbdomenCT-1K CC BY 4.0 1062 readme
0010_verse VerSe – Vertebrae Labelling and Segmentation Benchmark CC BY-SA 4.0 374 readme
0011_exact EXACT'09 – Extraction of Airways from CT Customized license 40 readme
0012_cad_pe CAD-PE – Computer Aided Detection for Pulmonary Embolism Challenge CC BY 4.0 40 readme
0013_ribfrac RibFrac Challenge Dataset CC BY-NC 4.0 660 readme
0014_learn2reg Learn2Reg – Abdomen MR-CT (TCIA Subset) CC BY 3.0 and TCIA Data Usage Policy 16 readme
0015_lndb LNDb – Lung Nodule Database CC BY-NC-ND 4.0 294 readme
0016_lidc LIDC-IDRI – Lung Image Database Consortium and Image Database Resource Initiative CC BY 3.0 997 readme
0017_lola11 LOLA11 (LObe and Lung Analysis 2011) Customized license 55 readme
0018_sliver07 SLIVER07 (Segmentation of the Liver 2007) Customized license 30 readme
0019_tcia_ct_lymph_nodes Lymph Node CT Dataset (NIH, TCIA) CC BY 3.0 174 readme
0020_tcia_cptac_ccrcc CPTAC-CCRCC – Clear Cell Renal Cell Carcinoma CC BY 3.0 258 readme
0021_tcia_cptac_luad CPTAC-LUAD – Clinical Proteomic Tumor Analysis Consortium Lung Adenocarcinoma Collection CC BY 3.0 133 readme
0022_tcia_ct_images_covid19 CT Images in COVID-19 CC BY 4.0 121 readme
0023_tcia_nsclc_radiomics NSCLC Radiogenomics CC BY 3.0 131 readme
0024_pancreas_ct Pancreas-CT CC BY 3.0 80 readme
0025_pancreatic_ct_cbct_seg Pancreatic CT-CBCT Segmentation CC BY 4.0 93 readme
0026_rider_lung_ct RIDER Lung CT CC BY 4.0 59 readme
0027_tcia_tcga_kich TCGA-KICH (Kidney Chromophobe) CC BY 3.0 17 readme
0028_tcia_tcga_kirc TCGA-KIRC (Kidney Renal Clear Cell Carcinoma) CC BY 3.0 398 readme
0029_tcia_tcga_kirp TCGA-KIRP (Kidney Renal Papillary Cell Carcinoma) CC BY 3.0 19 readme
0030_tcia_tcga_lihc TCGA-LIHC (Liver Hepatocellular Carcinoma) CC BY 3.0 242 readme
0032_stoic2021 STOIC (Study of Thoracic CT in COVID-19) CC BY-NC 4.0 2000 readme
0033_tcia_nlst National Lung Screening Trial (NLST) CC BY 4.0 7172 readme
0034_empire EMPIRE10 Challenge Customized license 60 readme
0037_totalsegmentator TotalSegmentator CC BY 4.0 1203 readme
0038_amos AMOS (Multi-Modality Abdominal Multi-Organ Segmentation Challenge) CC BY 4.0 200 readme
0039_han_seg HaN-Seg: The head and neck organ-at-risk CT & MR segmentation dataset CC BY-NC-ND 4.0 42 readme
0040_saros SAROS: A dataset for whole-body region and organ segmentation in CT imaging Mix of CC BY 3.0, CC BY 4.0, and CC BY-NC 3.0 900 readme
0041_ctrate CT-RATE CC BY-NC-SA 4.0 3134 readme
0042_new_brainct_1mm (Newly Released) BrainCT-1mm CC BY 4.0 484 readme
0043_new_ct_tri (Newly Released) CT-TRI (Triphasic Contrast-Enhanced Abdominal CTs) CC BY-NC-SA 4.0 586 readme

Citation

If you find this work useful, or use the CADS-dataset in your research, please cite:

@article{xu2025cads,
  title={CADS: A Comprehensive Anatomical Dataset and Segmentation for Whole-Body Anatomy in Computed Tomography},
  author={Xu, Murong and Amiranashvili, Tamaz and Navarro, Fernando and Fritsak, Maksym and Hamamci, Ibrahim Ethem and Shit, Suprosanna and Wittmann, Bastian and Er, Sezgin and Christ, Sebastian M. and de la Rosa, Ezequiel and Deseoe, Julian and Graf, Robert and Möller, Hendrik and Sekuboyina, Anjany and Peeken, Jan C. and Becker, Sven and Baldini, Giulia and Haubold, Johannes and Nensa, Felix and Hosch, René and Mirajkar, Nikhil and Khalid, Saad and Zachow, Stefan and Weber, Marc-André and Langs, Georg and Wasserthal, Jakob and Ozdemir, Mehmet Kemal and Fedorov, Andrey and Kikinis, Ron and Tanadini-Lang, Stephanie and Kirschke, Jan S. and Combs, Stephanie E. and Menze, Bjoern},
  journal={arXiv preprint arXiv:2507.22953},
  year={2025}
}
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