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00b7142d-80f8-e47a-40d9-11a0b6c5cb7f
OSA remains a prevalent chronic disease that continues to be underdiagnosed and untreated. OSA has multifactorial pathophysiology causing an increased risk of CVD states, metabolic dysfunction, mortality, and reduced quality of life due to a multitude of factors. The prevalence of OSA is expected to rise globally due to increasing obesity and the aging population in the next 30 years. Clinicians need to become familiar with the epidemiology and pathophysiology to efficiently screen for OSA and initiate effective treatment to prevent further health complications.
Obstructive Sleep Apnea in Adults: What Primary Care Physicians Need to Know
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Endovascular therapy often offers another therapeutic option for these patients. The use of transcatheter interventions has improved access to surgically inaccessible vessels and has reduced the need for general anesthesia as well as reduced blood loss secondary to trauma [61]. The added benefit of performing endovascular therapy during angiography has increased its use in trauma patients and is used in conjunction with both medical therapy as well as in stabilizing patients prior to definitive surgical intervention. Transcatheter interventions can be categorized into embolization, stents, and stent grafts.
State of the art: noninvasive imaging and management of neurovascular trauma
00b81d10-b297-6c1e-64c1-ead4fc5307e1
A total of 556 patients consecutively admitted to the sleep laboratory between January 2012 and July 2012 who are with symptoms of nocturnal snoring and/or excess daytime sleepiness and who underwent a polysomnographic evaluation were retrospectively evaluated. Patients having AHİ < 5 were grouped as control and others were grouped according to their AHI value as mild, moderate, and severe OSAS.
Is Mean Platelet Volume Really a Severity Marker for Obstructive Sleep Apnea Syndrome without Comorbidities?
00b93744-054f-51ef-4c0a-aafe8a6783c2
It is vital to have additional information regarding the intricate anatomy of the submandibular region, a potential risk in implant surgery. This could better assist clinicians in implant planning decisions. So, a study was set up to look at the straight line between the MC and the MR and see if there was a link with the morphologic variables of SMF. The null hypothesis is that there is no linear relationship between the MR and the MC in the M1 and M2 regions. These findings can be used to project the average superio-inferior position of the MC, derive an anatomic average between the MC and the MR, and provide additional important information about implant length and angulation during the implant planning stage. The goals of the study were to find out the average distance between MC and MR in the mandibular M1 and M2 region on both sides, find out the morphologic variables of SMF undercut in terms of depth in the horizontal dimension, relative depth in the horizontal dimension, depth in the vertical dimension, angle, and relative angle, and find a relationship between the bone height between MC and MR and the anatomical variables of SMF.
Mylohyoid Ridge as a Predictor of Available Bone for Implant Placement: A Cone-Beam Computed Tomography (CBCT) Retrospective Observational Study
00b9e83d-f838-c6c6-e4f0-3670044ccf80
The present systematic review showed that the use of aligners is recommended in simple malocclusions.
Efficacy of clear aligners in controlling orthodontic tooth movement: A systematic review
00bcd036-ce2e-10de-2efa-a32ebe64d3e1
A total of 423 males and 385 females were examined. Of these 394 were 3 years of age, 282 were 4 years and 132 were 5 years of age. Males and females were pooled in each age group as there were no significant differences between them with respect to occlusion.
Characteristics of Primary Dentition Occlusion in Preschool Children: An Epidemiological Study
00c383fd-8989-cf2d-3c66-d6a572fcf195
The vertical dimension of the MAD did not significantly influence the effectiveness of the treatment with an adequate mandibular protrusion. However, it was recommended not to exceed the 8 mm of interincisal opening to facilitate better acceptance of the device by the patient.
Upper Airway Characteristics and Morphological Changes by Different MADs in OSA Adult Subjects Assessed by CBCT 3D Imaging
00c6231c-e177-0f9b-b406-3500158dae67
A rapid maxillary expansion appliance anchored on primary second molars is effective in expanding the permanent molars to correct a transverse maxillary deficiency in prepubertal patients, transferring the risks associated with the large forces used to the primary teeth.
Expansion of permanent first molars with rapid maxillary expansion appliance anchored on primary second molars
00c6625c-8299-4764-5d6d-c67c4df32cd5
To the best of our knowledge, the present study is the first artificial neural network- based approach for automatic and accurate estimation of AHI and ODI using only a blood oxygen saturation signal. By first estimating the numeric values of AHI and ODI and determining the severity category of OSA based on those values, a more accurate estimation of the OSA severity can be achieved beyond the severity classification. In addition, the determination of the numeric value of AHI enables the neural network-estimated OSA severity to be directly compared to OSA severity assessed by standard manual scoring.
Artificial neural network analysis of the oxygen saturation signal enables accurate diagnostics of sleep apnea
00c95703-eaad-d98e-36e5-e51e1f75b4b1
The hippocampus is central to working and episodic memory and is critically affected by diverse disease processes. To investigate hippocampal electrophysiology in translational large animal models, we developed an imaging-free stereotaxis and intraoperative electrophysiology methodology with custom silicon probes to precisely localize probe placement within the hippocampal laminar structure. We report for the first time the profile of single units and local field potentials in the pig dorsal hippocampus and relate them to a histologic description. This characterization forms the basis for accessible translational pig models to study diseases of the central nervous system affecting hippocampal circuitry in the large animal gyrencephalic brain, as well as the groundwork for potential awake behaving neurophysiology of the porcine hippocampus.
Electrophysiological Signature Reveals Laminar Structure of the Porcine Hippocampus
00cc6316-6b42-0e71-5594-4c3ef1879048
The posterior maxilla is often a complicated area for implant placement due to low quality or quantity of bone. To increase the amount of bone and improve the implants fixation, it is usually performed maxillary sinus floor elevation techniques which actually are predictable procedures that allow the creation of new bone improving primary stability and future osseointegration.
Osteotome sinus floor elevation without grafting material: Results of a 2-year prospective study
00cd8c01-a72f-848b-c6fd-9be86da7b489
The study was carried out from March 2021 to March 2022.
Risk factors for the development of surgical site infection in bariatric surgery: an integrative review of literature Fatores de risco para o desenvolvimento de infecção de sítio cirúrgico em cirurgia bariátrica: revisão integrativa Factores de riesgo para el desarrollo de infección del sitio quirúrgico en cirugía bariátrica: una revisión integradora
00ce8720-03da-c58b-4135-44433d163f81
Bibliometric research uses statistical and mathematical methods to analyze and build indicators on the dynamics and evolution of scientific and technological information on a given topic.
Uses of Bibliometric Techniques in Public Health Research
00d09529-f51f-c934-fbb1-95dda2111ef8
The result of multiple regression showed that the smoking habit was not the independent factor for the cost of OC patient. But the proportion of smoker in late stage was higher than that of early stage and the proportion of smoker in SCC was obviously higher than other group. These results indicated that smoking were associated with stage and pathology of OC and would associate with the cost of OC patient indirectly.
Epidemiology and cost analysis for patients with oral cancer in a university hospital in China
00d0d06a-0d0b-7a06-ca3a-b3891f50dbef
As already highlighted above, the relatively small number of cases is due to the fact that there are few patients with class III skeletal malocclusion in which there is an indication of an isolated mandibular setback surgery.
Upper Airway Changes and OSAS Risk in Patients after Mandibular Setback Surgery to Treat III Class Skeletal Malocclusion
00d1bb15-153b-71e3-c7b5-5f34c276f451
Poor sleep quality is common among nurses. This problem possibly results in negative emotional and psychological consequences in nurses which secondary affect their work performances. However, in Ethiopia, there is a paucity of information about poor sleep quality and associated factors among nurses. This study aimed to assess the prevalence of poor sleep quality and associated factors among nurses working at comprehensive specialized hospitals in Northwest Ethiopia.
Sleep quality and associated factors among nurses working at comprehensive specialized hospitals in Northwest, Ethiopia
00d311c2-d73c-cf20-896a-8981ff71d4ad
We did find differences in terms of postoperative splinting time; this was not surprising, as we only applied splinting for a very brief time on some of the patients on the screw group for comfort purposes. The mean return to work time or time back to their regular activities appeared to be shorter on the screw group.
Intramedullary Screws versus Kirschner Wires for Metacarpal Fixation, Functional, and Patient-Related Outcomes
00d64a2d-431e-f0fa-7f19-1fdd80bc4aff
Evidence of concurrent caudal brain stem displacement was based on evidence that the cervicomedullary junction (using the obex as a landmark) approached or passed the foramen magnum line. The posterior fossa structures were among the most stable in our analysis and thus are not a useful finding in either diagnosis or grading IH severity.
An Objective Study of Anatomic Shifts in Intracranial Hypotension Using Four Anatomic Planes
00da5508-88e7-5b3f-27e6-8b454067d50b
It is critical to understand, at both the clinical and population level the determinants of the transition in health service utilization in the late life course. Transitions, in this study, refer to changes in the pattern of health service utilization over time, particularly in relation to the number of health service utilization events an individual experiences over a set period of time. It is likely that this is a dynamic process influenced by a large number of factors including changes in health status. Transitions in health services utilization can be understood as events in a dynamic system occurring with measurable probability. These probabilities may vary by the age and gender of the individual.
Measuring change in health status of older adults at the population level: The transition probability model
00db4f1d-2f8d-fc1c-4d69-8e9b9295f1ef
The findings of this study demonstrate that odontoblasts may be exposed to cytotoxic concentrations of HP and free oxygen radicals during teeth whitening, with molars being the tooth type at the highest risk.
Hydrogen Peroxide Diffusion through Dental Tissues—In Vitro Study
00dc35c2-be41-e7f0-b6a0-ca78d288a4df
Historically, the dental pulp was believed to be very vulnerable to tissue insult from bacterial carious attack and the resulting inflammation. The low compliance dentinal walls and lack of collateral circulation was thought to limit the ability of pulp tissue to accommodate increases in intra-pulpal pressure or effectively deliver humoral and cellular immune components to the injured site. The diagnostic consensus was that cariously exposed pulp in mature permanent teeth should be considered irreversibly inflamed based on the rationale that the underlying inflammation has spread throughout the pulp tissue and the restricted blood supply through the closed apices of mature teeth would not be enough to promote healing, even if the tissue insult is removed.2 However, studies have shown that dental pulp can not only accommodate moderate increases in intra-pulpal pressure during inflammation,5,6 but that the dental pulp also has an effective immune defence response.7,8,9
Minimally invasive endodontics: a new era for pulpotomy in mature permanent teeth
00dc7a03-3ba7-058b-f0f1-e288ef540ab1
This study presents a description and evaluation of an algorithm to detect snoring episodes during sleep by applying a time analysis of electric signals that are equivalent to snoring sound signals.
Computerized analysis of snoring in Sleep Apnea Syndrome
00e3368b-c3a7-0c88-8096-c5d0f1e4706b
Intraoperative risk factors for bleeding include a long aortic cross-clamp time and large blood loss requiring massive blood transfusion and fluid replacement. Bleeding from the disruption of aortic graft anastomoses is a major surgical concern after open aortic repair. Strict blood pressure control is imperative until the risk of surgical postoperative hemorrhage is low enough to allow for a return to the patient’s preoperative hemodynamic profile. When a massive red blood cell transfusion is required, a resuscitation approach using fresh frozen plasma is beneficial in reducing the intravascular depletion of clotting factors [15].
Postoperative Intensive Care Management of Aortic Repair
00e6903b-497a-36b4-92c4-f0459607b98f
Another great advantage of this system is that all steps in the diagnosis and therapy of the patient are traceable at any time. If surgical obstacles arise intraoperatively, an alternative procedure with this system can be carried out with a minimum of effort and the complete tumor resection can still be ensured. Thus, the goal of improving the success of the treatment, optimization of interdisciplinary collaboration and the patient’s quality of life through complete tumor resection and adequate reconstruction is retained.
Advances in the Resection and Reconstruction of Midfacial Tumors Through Computer Assisted Surgery
00e7652f-466b-12d0-e68d-7f122335d1f6
The main signs and symptoms of CBT include a slow growing pulsating mass at the level of carotid bifurcation and a peripheral cervical neuropathy related to the largest tumours but they may be clinically silent for a long time even when malignant.
Carotid body tumors: radioguided surgical approach
00ec9877-bdfb-fc87-cc9d-37de79df0669
Mental Health May Be an Important Confounding Variable and Comorbidity
Diabetes, Polycystic Ovarian Syndrome, Obstructive Sleep Apnea, and Obesity: A Systematic Review and Important Emerging Themes
00ee1fae-c9d5-09a6-70fb-1d470c010a10
We obtained Hospital Human Research Ethics Committee approval for implementation of the MET and for collection of data related to the study. The need for informed consent was waived by the Hospital Human Research Ethics Committee.
Effect of the medical emergency team on long-term mortality following major surgery
00eed0eb-9964-2f80-19a2-7d456b440443
In conclusion, this study describes a generic mathematical framework that can extract a pharmacodynamic profile of clonidine from raw EEG data collected from a fronto-parietal electrode derivation in freely-moving rodents, which could offer an alternative approach to study drug effects in early clinical trials. The model is based on a numerical analysis tool whose field of application is nonlinear dynamic systems. This innovative approach can potentially provide a translatable analysis methodology for assessing central pharmacodynamic effect and bridge the preclinical and clinical EEG observations.
Evidence of a pharmacodynamic EEG profile in rats following clonidine administration using a nonlinear analysis
00f1a0ed-0263-241c-9f96-3073381769e5
In the following Sections The Virtual Coupling Method and The Virtual Constraint Method, the methods for simulating the two stages will be explained, and we focus on the virtual constrained method.
Haptic Rendering of Diverse Tool-Tissue Contact Constraints During Dental Implantation Procedures
00f1bf6e-56e9-fff4-5e4c-1e075ad7f927
The mandibular inter-mental area is assumed to be a safe area for implant insertion and is involved in many other surgical procedures. It is essential to understand the anatomy of the region for avoiding injuries to the neurovascular bundles. Provided that the inferior alveolar or mental nerve is damaged during preparation of an osteotomy, sensory dysfunction appears due to nerve damage in the foraminal area. Recently developed all-on-four procedure permits a quick placement of 4 dental implants in the interforaminal area of the lower jaw associated with a fixed bridge during only one appointment. The mental foramen is a strategically important landmark during osteotomy procedures. The inferior alveolar nerve may extend beyond the mental foramen as an intraosseous anterior loop. The location of foramen, as well as, the possibility that an anterior loop of the mental nerve may be present mesial to the mental foramen need to be considered before implant surgery to avoid mental nerve injury. The mandibular canal contains the inferior alveolar nerve and blood vessels and is divided into mental and incisive segments between the roots of premolars. The mental canal deviates toward the mental foramen. However, the incisive canal continues below the incisor teeth where it generally is divided into a plexus of nerve branches until its main trunk is lost (1-3). In this area lingual foramen is also present that is located in the midline, leveled with or superior to the genial tubercles. The foramen has a branch of the incisive artery that anastomosis with the lingual artery (4).
Characteristics of anatomical landmarks in the mandibular interforaminal region: A cone-beam computed tomography study
00fb7c47-deb8-9985-1145-a9ea21e83785
Probabilistic fasteners are biologically inspired clamping devices that are interlocked by stems on each surface. Due to dynamic characteristics of fastening mechanism, friction inevitably occurs between stems in a vibrating environment. The use of the probabilistic fastener as a vibration reduction component were investigated with advantages from friction-induced damping in this study. The dynamic stiffness and loss factor of the probabilistic fastener were derived from the vibration interaction with a mechanical structure. This allowed determination of energy dissipation due to the friction in hook and loop from the wave propagation analysis. As the vibration amplitude increased, the loss factor of the fastener gradually increased because the friction between multiple stems increased. With the probabilistic fastener application, the vibration generation and transmission were reduced compared to the bolted joint due to the inherent frictional contacts. With this unique advantage, the probabilistic fastener has potential applications when large damping is required with additional benefit on the reduced weight.
Use of probabilistic fastener velcro as a friction-induced vibration damping treatment
00fcb2db-ef53-14da-81e3-4cd6b8517366
Anterior mandibular overjet is characterized by the anterior (labially) position of the mandibular incisors in relation to the corresponding maxillary incisors. Mandibular protrusion or crossbite was measured with the aid of a CPI periodontal probe and recorded in millimeters. Vertical open bite was characterized by lack of overlapping between maxillary and mandibular incisors.
Socio-economic indicators and predisposing factors associated with traumatic dental injuries in schoolchildren at Brasília, Brazil: a cross-sectional, population-based study
00fd0f11-4e36-54e0-3f68-3c4abcc5572c
This study was carried out to determine maxillary and mandibular arch width changes after orthodontic treatment in Angle Class II division 1 malocclusion subjects, treated either with or without extraction of the maxillary first premolars, and to compare the dental arch width changes in the treatment groups for both males and females. To the best of our knowledge the present study for the first time investigated the subjects treated with extraction in the maxillary arch and non-extraction in the mandibular arch.
Arch width changes in patients with Class II division 1 malocclusion treated with maxillary first premolar extraction and non-extraction method
00ff4da4-2d13-79a4-9397-e28c2e9b4cfd
The allocation of RFID codes, unique to each textile item that is sanitized in industrial laundries, could solve multiple problems in the process control of the internal and external circulation chain of professional textile products.
A New Washable UHF RFID Tag: Design, Fabrication, and Assessment
01069279-f0b6-951c-b55a-488ce2639bae
Contrary to the large light-induced NREM sleep promotion, REM sleep is affected to a far lesser extent by light–dark alternation under short-duration ultradian LD cycle. Given that REM sleep appears only after a consistent period of NREM sleep, short light pulses could be sufficient to promote NREM sleep but longer exposures might be necessary to significantly promote REM sleep. This hypothesis is supported by our results obtained under the T7 cycle, where REM sleep is significantly increased during light pulses compared to dark exposures. These data suggest that REM sleep induction by light might be secondary to the NREM sleep induction.
Direct Effects of Light on Sleep under Ultradian Light-Dark Cycles Depend on Circadian Time and Pulses Duration
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In this study, to evaluate changes in the neuromuscular activity, the ssEMG values taken at baseline were considered as reference for comparison with the following timepoints since all patients included in the study were without disorders at the stomatognathic apparatus or neck muscles. Although the present work is focused on a small sample of patients and a high interindividual variability can be found [30], it is interesting to observe that no altered values of muscular imbalance have been detected in both groups at T3. This could suggest that the effects of orthodontic treatments in patients with simple/mild malocclusion, when correctly planned and monitored, are associated to a maintenance of a neuromuscular stability [31,32]. Future studies with a larger sample size are needed to draw a more reliable and supported conclusion about neuromuscular responses during orthodontic treatment performed by means of aligners or traditional fixed appliance even on subjects with functional disorders.
Neuromuscular Stability of Dental Occlusion in Patients Treated with Aligners and Fixed Orthodontic Appliance: A Preliminary Electromyographical Longitudinal Case-Control Study
010d6190-684a-e6f5-54d3-215739b47213
To systematically review all available studies of operatively treated proximal tibia fractures and to report the incidence of superficial or deep infection and subsequent outcomes.
Infection following fractures of the proximal tibia – a systematic review of incidence and outcome
010f3787-190b-30bc-ecaa-86365f67c418
Thus, our motivation was to use an animal model to determine the potential for a causal link between right heart failure and impairments in sleep architecture. We adopted a PAB intervention that induced elevated PA pressure and produced a RV-specific hypertrophy. An alternative intervention using aortic banding would have impacted both LV and RV function, potentially resulting in a more complex sleep phenotype. However, having now established interesting and internally consistent impairments in sleep architecture with PAB banding, there is now a framework for interpreting sleep responses in a model of aortic banding.
A phenotype of increased sleepiness in a mouse model of pulmonary hypertension and right ventricular hypertrophy
01108bad-421c-5a2b-3873-68ea49e7b5ce
Bibliometrics is the statistical analysis of published documents. This is used for the qualitative and quantitative analysis of published literature. Bibliometric analysis is used in many different research areas to explore the productivity and impact of a specific research field or specific researchers, and to evaluate the research activities in many scientific fields. Over the last decade, bibliometric analyses have been conducted for many human infectious diseases. However, no such studies have been conducted on the scientific research output for CLCuD. Thus, the aim of this study is to characterize and quantify the research productivity on CLCuD at the global level using bibliometrics. Our study provides an overview of the previous research conducted on CLCuD and identifies the leading countries and institutes involved in CLCuD research. The results identify possible future collaborations which may have a significant impact on increasing the research output and progress on the subject.
Bibliometric analysis of publications on research into cotton leaf curl disease
0111bab9-5dc8-b403-51b1-6c817735b9ae
This is a showcase for the technical description of a full digital workflow aimed to reconstruct and prosthetically rehabilitate the mandible after surgical resection.
Full Digital Workflow for Mandibular Ameloblastoma Management: Showcase for Technical Description
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The difference in Ra values in different groups was calculated and statistically analyzed before and after the wear test. The mean changes in Ra are shown in Figure 1. Ra changes were the greatest in group 6 and the lowest in group 4.
Effect of Mechanical Loads and Surface Roughness on Wear of Silorane and Methacrylate-Based Posterior Composites
0116960b-9e54-490f-5d29-33b860ab950f
In our study, we selected children from 8 to 10 years old age and compared the eruption percentage of two teeth, namely canine and first premolar in the mandible. The age group selected is corresponding to the mixed dentition age when most of orthodontic interceptions could be effective. Often crowding is more severe in the mandibular arch as there are several mechanisms to resolve the lack of space in the maxilla .
Tooth eruption sequence and dental crowding: a case-control study v1; ref status: indexed
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Our findings suggest that there are an increased number of cases reporting in the ages 10 to 13 years, with a sizable number of them being boys. Many cases reported more than a year after trauma, frequently when the symptoms appear. Half the teeth examined were seen to be in a devitalized condition. The causes of trauma are the same ones frequently encountered in the literature. The barriers for late reporting need to be analyzed.
Analysis of Reporting Pattern in Children Aged 7 to 14 Years with Traumatic Injuries to Permanent Teeth
01183543-9d0b-a43f-0718-0ae2d2a8a4fd
It is necessary to emphasize that endodontic therapy requires other phases in addition to instrumentation. Despite all the technological development in the sector, there is still no instrument that meets all the requirements for optimal root canal preparation [27]. This fact highlights the importance of choosing a good irrigation solution and a filling that promotes three-dimensional sealing of the root canals. Another important point to emphasize is that the three systems represented safe alternatives for root canal preparation, but no system has been shown to be an absolute substitute for manual instrumentation.
Economic analysis of the different endodontic instrumentation techniques used in the Unified Health System
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The geometry of the molecule provides some indication of where the symmetry elements can be. The eigenvalues and eigenvectors of the inertial tensor are the principal moments and axes of inertia for the equivalence set:where is the identity matrix in three dimensions. These eigenvalues and eigenvectors are calculated using a Jacobi algorithm for matrices.
Automatic procedure for generating symmetry adapted wavefunctions
0119a4e0-db74-d624-8c31-18f7de11739c
Conclusion The management of long-term retention could be improved by more effective communication between the orthodontist and GDP. One solution might be a retention management pro forma. GDPs are in some instances willing to undertake more of the management of retention following further training and possible remuneration.
Orthodontic retention and the role of the general dental practitioner
011ac107-a613-babf-42ad-b8b558b345f1
The aim of this study was to evaluate the effect of surgical specialization and surgeon resection volume on short-term outcome after emergent colon cancer resections.
Effects of surgical specialization and surgeon resection volume on postoperative complications and mortality rate after emergent colon cancer resection
011e2175-d42f-9253-3f2a-d098332734e9
The diameter of the left posterior hemiarch was measured as a linear distance between the central fossa of the first left molar and the median palatine raphe of the upper maxilla (Figure 6).
Transverse Asymmetries of the Maxilla Even in Healthy and Apparently Symmetrical Subjects
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Atrial strain and strain rate echocardiographic evaluation is a useful method for the evaluation of atrial stunning in AF cases where SR has been achieved. In cases having had cardioversion due to persistent AF, this new method is superior to the A wave measured from the mitral and tricuspid valve with pulse Doppler and the dependent parameters of A wave speed-time integral, E/A rate and atrial ejection force in demonstrating the continuation of atrial stunning. Atrial strain and strain rate echocardiographic examination reflects atrial systolic functions quantitatively, and can be used safely both in the diagnosis phase and in planning optimal medical treatment, including anticoagulant therapy in cases with persistent atrial stunning.
Atrial Strain and Strain Rate: A Novel Method for the Evaluation of Atrial Stunning
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Second, the CBCT was utilized to evaluate the drilled skull phantoms with the custom-made planning tool. Within the image data, the start and end point of the drilling were visually determined and used to define the trajectory of the drilling after image registration using the reference frame. and were used again to calculate and and the Euclidean distances to and to provide a measure for the drilling error at both locations.
Concept description and accuracy evaluation of a moldable surgical targeting system
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Two coronal reconstructions were made at the anterior and posterior part of the corpus callosum. The third section was taken about halfway along this structure in order to include the pituitary gland and sphenoid bone as reference points. The cranial and lateral attachments of, respectively, the falx cerebri and tentorium cerebelli as well as the brain sulci served as additional landmarks for orientation.
Clinical validation of the normalized mutual information method for registration of CT and MR images in radiotherapy of brain tumors
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The aim of the study was to investigate the relationship between reported ear symptoms and different dysfunction symptoms, factors of dental occlusion, oral parafunction and habits in patients referred to a TMD clinic, to better understand and treat the ear symptoms.
Ear symptoms in patients with orofacial pain and dysfunction ‐ An explorative study on different TMD symptoms, occlusion and habits
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Another important finding of the present study is that while multimorbidity is associated with undiagnosed OSA, those with exactly two CDs are not at an increased risk of OSA. The proportion of those with three or more CDs increased with positive OSA status but also with severity status making the use of three CDs a more interesting cut-off than the two CDs generally used in multimorbidity to investigate OSA status but also severity as previously suggested [14].
Association between multimorbidity and undiagnosed obstructive sleep apnea severity and their impact on quality of life in men over 40 years old OSA, multimorbidity and quality of life
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Posterior spinal fusion is a common surgery that can successfully halt progression of idiopathic scoliosis and improve spinal deformity. The primary concerns with spinal fusion are that loss of motion through the involved spinal segments can decrease overall flexibility, impact body mechanics, and potentially put patients at increased risk for injury or complications with return to sport.
Return to play following spine surgery
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If the score is below 9, the union is unpredictable and there are high chances of delayed or nonunion without surgical intervention.
Percutaneous autologus bone marrow injection in the treatment of delayed or nonunion
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We will continue to strictly focus on the formal mechanism of ulcer formation. Aschoff’s postulate brings another argument into the old dispute on the nature of peptic ulcer: Gastric ulcers of the proximal antrum exhibit a sharp border towards the parietal cell mass and run out shallowly away from the acid-secreting mucosa. In contrast, ulcers developing inside the duodenal mucosa display a rotational symmetry with acute borders at all sides. For duodenal ulcer we will have to show the conditions for the possible development of a supply/demand conflict under the local condition of a homogenous mucosa as well as the morphological outcome of such a condition.
A Differential Approach to Form and Site of Peptic Ulcer
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Knowledge of changes in the dental transition stage could be important to the implementation of preventive approaches for children in this age group. Furthermore, it has been shown that malocclusion and its consequences are not only reflected in childhood, but may persist throughout life. Thus, the aim of the present cohort study was to assess the influence of early childhood malocclusion on OHRQoL. Our hypothesis was that children who experienced malocclusion in early childhood will report a worse OHRQoL than their normal counterparts.
Influence of malocclusion on oral health-related quality of life in children: a seven-year cohort study
013a0fb9-28cd-b431-625f-99f88ffb332c
A Transpterygoid approach with ipsilateral HBF for skull base reconstruction while preserving ipsilateral sphenopalatine artery is a possible surgical option and it can be considered for skull base reconstruction. The present article and the previous literature showed that deep anatomical knowledge, surgical expertise and careful dissection of neurovascular structures are fundamental to achieve wide exposure of pterygoid base without compromising the blood supply of ipsilateral nasoseptal flap. Furthermore, this technique can be used for skull base reconstruction in case of bilateral TAs or TA combined with other endoscopic approaches (i.e. CSF fistula of lateral recess of sphenoid sinus and extensive tumors) or for those cases with only one vascular pedicle available.
Ipsilateral Nasoseptal Flap Pedicle for Transpterygoid Approach: Technical Note
013c8a34-e322-bb29-b4e8-f89e5f0c357e
The etiology, diagnosis and management of mandibular asymmetries focuses particularly on developmental asymmetries. Increasing mandibular asymmetry with bilateral asymmetry of morphological traits causes malfunctions in developmental homeostasis, associated with environmental and/or genetic stresses. The development of morphological asymmetry may serve as a risk factor for disorders of developmental origin if these stresses are involved. The biopsychosocial model is hypothesized to be the most accepted theory for developmental asymmetry and complexity of TMD . Studies concerning TMD and the relevance of orthodontic treatment suggest that the achievement of a balanced in the dynamic occlusion is necessarily related to the development of mandibular symmetry as a part of the successful management of TMD .
TMD symptoms and vertical mandibular symmetry in young adult orthodontic patients in North Sumatra, Indonesia: a cross-sectional study [version 2; referees: 3 approved]
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A composition of two different material patterns can be easily recognized in all the samples.
In Vitro Evaluation of Structural Factors Favouring Bacterial Adhesion on Orthodontic Adhesive Resins
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The second aspect of the problem is the behaviour of the deposited filament. To hold the filament in place, a sufficient adhesion bond must be formed. This requires longer processing times and higher pressure of the nozzle at the nip point. If the bonding is not fully formed, then bending stresses built in the reinforcements drive the filament from the desired path.
Steering Potential for Printing Highly Aligned Discontinuous Fibre Composite Filament
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In an attempt to achieve primary fixation with the non-threaded implant, socket preparation must be undertaken with great care. Over preparation will lead to a lack of primary stability of the implant. When under prepared the implant must be pushed firmly into the socket with a potential risk of displacement into the maxillary antrum, or damage to the fragile HA coating.
A 3 to 4 year study of single tooth hydroxylapatite coated endosseous dental implants
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There are no randomized trials on the use of this solution to prevent adhesions after ASIO operation currently present in the medical literature.
Prospective controlled randomized trial on prevention of postoperative abdominal adhesions by Icodextrin 4% solution after laparotomic operation for small bowel obstruction caused by adherences [POPA study: Prevention of Postoperative Adhesions on behalf of the World Society of Emergency Surgery]
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The subgroup entered into surgery with less hearing as evidenced by lower preoperative AzBio scores compared to the general population. This variable is likely highly associated with age at implantation and duration of deafness. Within the confines of this study, it was not possible to analyze as an isolated variable.
Comorbidity associated with worse outcomes in a population of limited cochlear implant performers
014c08e8-cfe3-884e-b430-8e725dafe65b
Group 3 displayed a significantly higher torsional stiffness while a comparable axial stiffness to group 2.
Biomechanical Assessment of Three Osteosynthesis Constructs by Periprosthetic Humerus Fractures
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Accurate liver resection is very significant for a better outcome in curing patients with liver cancer. Three-dimensional visual reconstruction technology combined with virtual surgical planning is used in this work. The 2D CTA images of liver cancer are preprocessed at first. Then, the images are reconstructed into a 3D image using ENURBS for efficient visualization and diagnosis of liver cancer. Finally, planning of the surgical methods based on the 3D reconstructed liver model for precise liver resection is performed using VSP. The flow of the proposed work is shown in Figure 1 and explained in this section.
Influence of Three-Dimensional Visual Reconstruction Technology Combined with Virtual Surgical Planning of CTA Images on Precise Resection of Liver Cancer in Hepatobiliary Surgery
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Interviews were recorded with the use of an encrypted digital audio recorder to which only the lead researcher had access. Interview recordings were then downloaded to a secure server and were password protected with access only to the lead researcher. The interviews were transcribed verbatim and all identifiable information was removed to ensure participant confidentiality. Interview transcripts were stored on a secure server and pseudonymised by a unique study ID number. Once transcribed, interviews were uploaded to NVivo (V.12, QSR International) for analysis. We used thematic analysis to analyse the data. A second researcher (ZHL) duplicated the coding process in a sample of four of the interviews to ensure dependability and consistency in the analysis process.15 Transcripts were coded independently and then each interview transcript was discussed between the researchers to ensure agreement. Any sections of the transcripts which we did not agree on the coding for were discussed to reach consensus agreement on the most appropriate code to use in that section. We performed the analysis concurrently with the data collection and interviews were terminated when no new themes were emerging from the data.
Patient experiences of an ankle fracture and the most important factors in their recovery: a qualitative interview study
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The recently introduced variable angle stable locking system allows the surgeon to vary the screw angle and direction. Thus, a fracture adapted screw positioning can be performed with the benefit of angular stable locking. Combining this with a preoperative plan regarding the screw position, an osteosynthesis that is modelled to the specific fracture and bone quality is possible. This might increase the mechanical stability of the bone implant construct and has the potential to decrease complication rates.
Development and first biomechanical validation of a score to predict bone implant interface stability based on clinical qCT scans
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The simple fixed-fixed beam resonator test structure was described earlier in the section on the impact of residual stresses. A resonator test structure can be used to measure the residual stress in thin-film material layer. The key issue in using a resonator to determine the residual stress in a material layer is that the resonant frequency is shifted due to the presence of the residual stress compared to the same resonator without a residual stress. Using Equation (1) enables a very accurate determination of the residual stress as long as the dimensions are accurately known since the resonant frequency can be measured very accurately.
Review Paper: Residual Stresses in Deposited Thin-Film Material Layers for Micro- and Nano-Systems Manufacturing
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Oral maxillofacial surgeons must be involved in the daily preventions of these injuries, giving to patients orientations about the risks and morbidity related to the abusive use of this substance. This orientation is mandatory since maxillofacial trauma associated to alcohol consumption tends to relapse.
Alcohol abusive use increases facial trauma?
01583a9a-ac86-11cd-2f86-8feaecd30f4e
A robust referral management system should be introduced to deter inappropriate referrals. Many primary care trusts in England have introduced central referral management centres where referrals are scrutinised by a clinician or an administrator before rejecting or redirecting referrals to appropriate providers. Alternatively, strict referral criteria and a standardised referral pro forma could be introduced and compliance scrutinised through audit process. Targeted education and management of providers and referrers is required to ensure compliance with the referring system in place. Simply distributing referral guidance to referring practitioners will not be effective. Advantages and disadvantages of each referral system should be analysed before their implementation. In Wales, some regional managed clinical networks (MCNs) are working towards introducing a referral management system in orthodontics.
Complexities associated with orthodontic services in the National Health Service
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In this research, assessment of alveolar changes in the maxilla was performed through linear measurements between buccal and palatal cortical bones. These measures are independent and are considered long enough not to be influenced by variation in the partial volume averaging. Additionally, voxel size was the same for all tomographic exams used in this study. That means that if there has been a tendency towards overestimating measures, this has happened to all measures, so that the differences between pre- and postretraction values would have been the same and the results would not have been altered. The limitation of contrast resolution would probably have introduced some bias, if bone thickness had been measured from the buccal and palatal surfaces of incisors roots in their cervical third, due to the smaller quantity of alveolar bone in that region.
Maxillary dentoalveolar assessment following retraction of maxillary incisors: a preliminary study
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Data from a previous study on fluoride release were used to estimate the sample size for the fluoride release data study [25]. Assuming that the fluoride release of Clearfil Universal Bond Quick is 18 ppm after 30 days and using an effect size of 1.2, it was determined that 16 samples per group were necessary for the study to detect statistical significance between the groups in fluoride release with a 95 percent power at the significance level of 0.05.
Shear Bond Strength and Fluoride Release of a Universal Adhesive: An In-Vitro Study on Primary Teeth
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The reduction is checked with the image intensifier and a nonlocking bicortical screw is inserted in the humeral shaft using the sleeve system of the insertion handle (Figure 2). This step allows improving the alignment of the shaft with the head by taking advantage of the shape of the plate.
Minimally Invasive Plate Osteosynthesis for Proximal Humerus Fractures: A Retrospective Study Describing Principles and Advantages of the Technique
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The number of cases treated by chemical capsuloraphy using sclerosing agents and platelet rich plasma could not be ascertained, 9 cases were treated with autologous blood in the superior joint space and 9 cases with injection into the space and pericapsular tissues. Also, number of cases of chronic recurrent dislocation that received surgical capsuloraphy and placation for lax capsule and ligaments was not obtained. Closed low level condylotomy to allow free movement was done in 2 cases while 4 cases received open condylotomy. Fifteen cases were treated with lateral pterygoid myotomy via intraoral approach (Table 4contd).
Evaluation of the mechanism and principles of management of temporomandibular joint dislocation. Systematic review of literature and a proposed new classification of temporomandibular joint dislocation
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Calculated bone density correlated very strongly with the known control density, confirming the accuracy of density calculations in real time. Drilling energy and screw insertion energy correlated very strongly with the measured pull-out force by destructive testing confirming ultimate pull-out force could be quantified during drilling or placement of a screw.
Dual Motor Drill Continuously Measures Drilling Energy to Calculate Bone Density and Screw Pull-out Force in Real Time
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Craniofacial bones constitute the most intricate part of human skeletal system. They determine the contour of the face by lending supports and attachments to the overlying soft tissues, and maintain diverse physiological functions in the craniofacial region by providing a stable structure foundation. In cases of congenital craniofacial deformities, which are the most common birth defects in human, craniofacial bones are often involved with compromised morphology and function. Usually, congenital anomalies affect craniofacial bones in two ways. First, abnormal embryogenesis and development generate primary distortion and defects in the bony structure. Second, the structural instability worsens the primary deformities and skews the growth pattern in a secondary manner. The primary distortion and defects could be clearly defined at birth, but the secondary growth abnormalities are still difficult to predict. Although congenital craniofacial deformities have been repeatedly related to the skeletal instability, neither the detailed instability pattern nor its correlation with specific tissue defects and growth pattern has been efficiently explored in the previous literature.
Functional stability analyses of maxillofacial skeleton bearing cleft deformities
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A cross-sectional analytical study was carried out on 155 children aged 6–12 years attended at the clinic of the School of Dentistry of Universidad Nacional Mayor de San Marcos in 2017.
Deleterious oral habits related to vertical, transverse and sagittal dental malocclusion in pediatric patients
0166e9e4-4326-b2cb-468f-e59d8f5b02cc
In order to overcome these challenges and obtain meaningful data from the digital pressure sensor, this study utilized an image processing software to eliminate artifacts that could be considered as a spread of pressure rather than definitive contact areas. Dark blue readings which represented the lowest pressure areas were considered artifacts and were filtered out by adjusting the color threshold in the imaging analysis software. This allowed for a more accurate reading of the contact surface area in terms of the pixel count. This methodology of using an image processing software to refine occlusal contact data has been previously utilized by Millstein and co-authors, who utilized this software to analyze photographs of light transmission through bite registration records [19]. The force distribution values from the digital pressure sensor were converted to a percentage of the sum of pressures on the three teeth evaluated for the study.
An In-Vitro Evaluation of Articulation Accuracy for Digitally Milled Models vs. Conventional Gypsum Casts
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All the authors were involved in the patient's care. RPN and NJ were involved in the initial care of the patient and RPN first raised the possibility of GBS. KR organized the relevant investigations and MJJ was the consultant who guided the overall management. All authors read and approved this final manuscript.
Guillain-Barré Syndrome presenting with bilateral facial nerve paralysis: a case report
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To investigate the effect of sudden deprivation of sensory inputs from the periodontium on jaw kinematics and time-varying activation profile of the masseter muscle.
Effect of Sudden Deprivation of Sensory Inputs From Periodontium on Mastication
0168ee93-81d1-7d6f-bee3-fcdc6f2d7a14
An interdisciplinary clinic provides the optimum environment for assessing patients with hypodontia.9 Close collaboration between several clinicians allows for more efficient treatment planning and consequently the delivery of care and the patients' experience is enhanced. A recent study by Tams and Ashley reported that 99% of patients found attending these clinics worthwhile.9 In addition to being beneficial for patients, combined clinics also offer valuable learning opportunities for all grades of dental trainee.9
The interdisciplinary management of hypodontia patients in the UK: a national service evaluation
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In conclusion, we have developed a model of oligodendrocyte death in the murine optic nerve that results in delayed demyelination, a lack of remyelination, and a muted response in adjacent glial cells. Such a model is potentially useful in understanding the cellular and molecular mechanisms that initiate myelin repair and as a platform for assaying the effectiveness of remyelinating therapies.
Targeted Oligodendrocyte Apoptosis in Optic Nerve Leads to Persistent Demyelination
016ff6ff-e08b-1f19-b687-5eb65ab83d9c
Class II patients benefitted very little from the orthognathic intervention. Possibly because only two out of four patients received bimaxillary osteotomy the changes from before to after the intervention were not dramatically. Furthermore in our videos the lateral views which enhance the perception of dysgnathia were only a small part of the presentation.
Facial esthetics and the assignment of personality traits before and after orthognathic surgery rated on video clips
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ChatGPT and similar generative AI chatbots have the potential to augment clinical decision making. By challenging the boundaries between machine and human expertise, this study sparks an important conversation about the evolving landscape of healthcare. Additional research is required to ensure the safety of this technology in a variety of clinical scenarios and levels of urgency.
Mind + Machine: ChatGPT as a Basic Clinical Decisions Support Tool
0174b69a-8c58-87f1-e179-c71a1af693fc
Dental professionals are prone to unique muscle imbalances and require special exercise and ergonomic interventions to maintain optimal health during the course of their career. It is important to not only know what are effective interventions, but also in what sequence to implement them.
Ergonomics in Dentistry
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Descriptive statistics for the alignment changes reported by patients at different intervals are presented in Table 1.
Patient-centered evaluation of alignment changes during the first stage of orthodontic treatment: A longitudinal observational study
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Chronic pseudoaneurysm may mimic some other pathologies of aorta including penetrating atherosclerotic ulcers, infected mycotic saccular aneurysm and vasculitis. Traumatic pseudoaneurysms are usually located at the isthmus, although they may occur anywhere in the aortic tree, and can be distinguished from penetrating ulcers from lack of dilation of adjacent aortic segments and lack of significant atherosclerosis as was the case for our patient. Similarly, infected aneurysm and vasculitis are not commonly found near the isthmus and are associated with lobulations and inflammation in aortic wall. In any case, CT angiography seems to be the best modality to confirm the diagnosis. Our patient had a history of falling from a few stairs 10 years earlier which was not severe enough for him to seek medical attention. Whether this has caused the pseudoaneurysm is a subject of debate. As noticed most traumatic injuries are associated with severe accidents while our patient had a minor trauma, but the location of the pathology and lack of atherosclerosis and other pathologies elsewhere in the aortic wall point to a traumatic origin. There is a possibility of spontaneous pseudoaneurysm, but most patients had hypertension as risk factor and presented acutely to the hospital with chest pain or back pain which was not the case for our patient. So this patient is interesting in this aspect that it may be the first reported case in literature for the delayed presentation of pseudoaneurysm only after a minor injury and blunt traumatic injury to aorta should be suspected even after an insignificant chest trauma with the deceleration injury mechanism.
Pulmonary artery stenosis caused by a large aortic arch pseudoaneurysm detected 10 years after a minor trauma
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When the groups were compared in terms of surface treatment, results revealed that shear bond strength values differed significantly between groups 1 and 2, with group 2 exhibiting higher values than group 1. It is speculated that this result occurred because, after curing, the composite resin requires macromechanical retentions to become attached to other material. Composite resin does not chemically react with the acrylic resin of temporary crowns, which gives support to the better bonding values yielded by roughened surfaces compared with surfaces without preparation.12 It is further speculated that the tertiary amines present in CAAR composition can inhibit adequate polymerization of light-cured composite resins, thereby impairing bonding between different types of material. Inhibition could also explain the lower bond strength values observed in groups 1 and 2 compared with the values observed in groups 3 and 4. It is emphasized that the strength values obtained for groups 1 and 2 were lower than what is considered as clinically acceptable.21
Evaluation of an alternative technique to optimize direct bonding of orthodontic brackets to temporary crowns
017974ab-066c-ea5b-96f4-e77f9d9b913a
A complication is defined as any occurrence or deviation from the normal treatment or outcome, regardless of whether it has any relationship with the treatment or product under investigation.
Does osteoporosis increase complication risk in surgical fracture treatment? A protocol combining new endpoints for two prospective multicentre open cohort studies
017986ae-a1f5-a549-7592-cf6f8cdff51a
Correct placement of dental implants in the mental region may be limited by this anatomic structure and its violation can lead to a neurosensory disturbance in the area of the lower lip.
A retrospective radiographic evaluation of the anterior loop of the mental nerve: Comparison between panoramic radiography and cone beam computerized tomography
017b28cb-705e-80e0-1157-d9b3866e6ee9
Relocation pharyngoplasty appears to be similar to lateral pharyngoplasty in splinting the lateral pharyngeal wall but has the distinctive characteristic of plicating the superior pharyngeal constrictor muscle to prevent scarring contraction of the tonsillar fossa. Advancement of the soft palate is achieved by removing the supratonsillar mucosa and adipose tissue to create a space for reconstruction of the velopharynx. In addition, this procedure preserves the palatal muscle by removing only part of the soft palate mucosal layer. Our study included patients with mild, moderate, or severe OSA who showed more than 50% narrowing in their lateral pharyngeal wall with tonsil enlargement, and we expected them to need more tension to improve lateral pharyngeal wall collapse. Based on our results, relocation pharyngoplasty resulted in approximately 53% successful surgical results in OSA patients and provided a higher success rate in moderate OSA patients, with 69% of OSA patients showing an improved AHI score and superior numerical changes in sleep parameters following relocation pharyngoplasty. We conclude that relocation pharyngoplasty is a favorable surgical option that maintains pharyngeal function in moderate OSA patients with retropalatal circumferential narrowing.
The clinical efficacy of relocation pharyngoplasty to improve retropalatal circumferential narrowing in obstructive sleep apnea patients
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Furthermore, it is not evident if the growth in number of publications involving bibliometric methods is merely facilitated by the rise in number of publications available for analysis. Most likely, a threshold has to be passed in in order to gain sufficiently statistics but other factors could play a role as well.
The bibliometric analysis of scholarly production: How great is the impact?
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This study aims to evaluate the effectiveness of 3D trapezoidal plates in open reduction and internal fixation of subcondylar fractures.
Evaluation of 3D Trapezoidal Plates in Open Reduction and Internal Fixation of Subcondylar Fractures of Mandible: A Clinical Trial
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We report a case in which there was in fact a small sentinel or herald bleed, as a prelude to massive exsanguination. Early recognition of a sentinel bleed may be essential to improve patient outcome.
Sentinel Bleeding as a Sign of Gastroaortic Fistula Formation after Oesophageal Surgery
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The reason why women are the majority of patients presenting for treatment remains unclear. Although the prevalence of one or more signs of mandibular pain and dysfunction is high in the overall population, only about 5 to 7% have symptoms severe enough to demand treatment.18 De Leeuw2 reported that after clinical worsening, as the situation becomes chronic, mouth opening tends to increase and the symptoms become milder due to adaptive changes in joint tissues. This situation was not reported by the patient who described that pain got worse day by day.
Manual reduction of articular disc after traumatic extraction of mandibular third molar: a case report
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CRP assessment identified horizontal resorption of less than 2 mm (minimal) was present allowing the crown to be centred on alveolar ridge in the buccolingual position
Restoratively driven planning for implants in the posterior maxilla - Part 2: implant planning, biomechanics and prosthodontic planning a proposed prosthodontic complexity index
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Further studies are required to assess the effect of skeletal parameters on the success rate of miniscrew insertion in orthodontic patients. Also, the effect of soft tissue parameters on the success rate of miniscrew placement should be investigated in future studies. Finally, a systematic review is required to reach a definite conclusion on this topic.
Interradicular distance and alveolar bone thickness for miniscrew insertion: a CBCT study of Persian adults with different sagittal skeletal patterns
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The main advantages of digital monitoring are the possibility of making more precise measurements of distances, and the reduction of work time, due to the abolishing of the need to request plaster casts to the dental technician, which also means the reduction of the costs for both the laboratory and the patients. By eliminating the steps of the analogue impressions and of the plaster casts, the details are certainly represented with more precision and accuracy and there is a minimum error accumulated. Moreover, this digital workflow can be managed entirely by a single person, which represents a further saving of time.
CBCT and Intra-Oral Scanner: The Advantages of 3D Technologies in Orthodontic Treatment
01858c4a-e14f-1ede-0f31-bbf0da8b6bf8
Two patients with excision of the radial head developed moderate instability.
Unusual patterns of Monteggia fracture-dislocation