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Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.1348 igad104.1348 Abstracts Session 3565 (Symposium) AcademicSubjects/SOC02600 LATENT HEALTH PROFILES ASSOCIATED WITH INSTITUTIONAL ADMISSION AFTER SNF STAY AMONG MEDICARE PLWH Olivieri-Mui Brianne Northeastern University, Boston, Massachusetts, United States Shi Sandra Hebrew Senior Life, Roslindale, Massachusetts, United States McCarthy Ellen Hebrew Senior Life, Roslindale, Massachusetts, United States Oh Gahee Hebrew Senior Life, Roslindale, Massachusetts, United States Kim Dae Hyun Hebrew SeniorLife, Roslindale, Massachusetts, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 408408 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background Health profiles may help identify PLWH at risk for institutional admission after a short-term skilled nursing facility (SNF) stay. Methods We estimated rates of institutional admission in one-year follow-up after discharge from a SNF stay (<100 days) among Medicare FFS beneficiaries with HIV (2014-2019). Latent profile analysis identified subgroups based on prevalent conditions one year prior to discharge including 8 indices: mental health (MH range 0-6), substance use (SU 0-4), cardiovascular conditions (CV 0-9), sensory (SE 0-4), musculoskeletal (MU 0-10), pulmonary (PU 0-2), learning disabilities (LD 0-9), and other chronic conditions (OCC 0-11). Cox models estimated the association between latent profiles and time to institution admission (hospital, nursing home), adjusting for demographics, dual eligibility, HIV treatment; censoring included death and study end. Results The 618 PLWH studied were male (73%), with mean age 60 (standard deviation [sd] 11). Two latent health profiles were: CV+OCC+MH (n=77), median values CV=3, OCC=2, MH=1; healthy (n=541), median 0 for all. Compared to the healthy group, the CV+OCC+MH group had similar days spent in an institute (60 days vs 66 days ), and similar hazards for institutional admission in adjusted models (HR:1.09, 95% CI [0.81-1.46]) in one-year after SNF discharge. HIV treatment for >=80% of the time prior to discharge had lower hazards (HR:0.76 [0.59-0.98]) and dual eligibility had higher hazards (HR:1.32 [1.09, 1.61]) of returning to an institutional setting. Conclusions Latent profiles had similar risk for institutional admission in one-year after discharge from a SNF stay, despite having significantly different contributing factors. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.1253 igad104.1253 Abstracts Session 3475 (Symposium) AcademicSubjects/SOC02600 FATIGABILITY, FITNESS, AND CHRONO-NUTRITION: RESULTS FROM THE STUDY OF MUSCLE, MOBILITY AND AGING (SOMMA) Glynn Nancy Chair Kritchevsky Stephen Co-Chair Schrack Jennifer Discussant 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 377378 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract The Study of Muscle, Mobility and Aging (SOMMA) is a new longitudinal cohort study conducted at the University of Pittsburgh and Wake Forest University School of Medicine, coordinated by the San Francisco Coordinating Center, with management of biological specimens by the Translational Research Institute at AdventHealth. SOMMA aims to provide the foundation for discoveries in the biology of human aging, mobility and other age-related phenotypes. SOMMA enrolled 879 older women and men; mean age 76.3+-5.0 years (range 70-94); mean walking speed 1.04+-0.20 m/s; 59.2% women, and 15.8% identify as other than Non-Hispanic White. Our symposium will introduce novel baseline SOMMA findings on key measures related to fatigability, fitness, and chrono-nutrition. First, Dr. Schumacher will share results on the association between perceived physical and mental fatigability and cognitive function. Next, to begin to decipher how skeletal muscle energetics impact aging phenotypes, Ms. Gay will examine the relation between skeletal muscle energetics (ATPmax and maximal complex I&II supported oxidative phosphorylation [maxOXPHOS]) and age-related physical fatigability. Our next two presentations will focus on cardiorespiratory fitness (VO2peak) measured by gold standard treadmill cardiopulmonary exercise testing (CPET), which declines with age. Ms. Moffit will explore whether a usual-paced 400m walk can predict VO2peak, and Dr. Erickson will examine the association between CPET measured VO2peak and circadian functions derived from rest-activity-rhythms extracted from wrist-worn accelerometers. Lastly, Dr. Farsijani will explore chrono-nutrition behaviors and their association with muscle health (i.e., D3-creatine, leg power). Discussant, Dr. Jennifer Schrack will provide insight to SOMMA's novel work. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.2804 igad104.2804 Abstracts Session 7670 (Poster) Pain Management and Palliative Care AcademicSubjects/SOC02600 THE INTERSECTION OF INSOMNIA AND CENTRALIZED PAIN IN OLDER ADULTS Smith Michael University of Michigan, Ann Arbor, Michigan, United States Dean Meagan University of Michigan Health, Ann Arbor, Michigan, United States Irwin Madison University of Michigan, Ann Arbor, Michigan, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 871871 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract The intersection of insomnia and pain with age has been broadly studied but has not been evaluated specifically in centralized pain. The objective of this study was to estimate the effect of age on rates of centralized pain and insomnia in older adults. This was a single center, retrospective, observational cohort study consisting of older adults (>=55 years old) with a diagnosis of centralized pain, insomnia, or both seen at University of Michigan Health from January 1, 2016 - January 1, 2022. The primary outcome was the proportion of older adults with both insomnia and centralized pain, defined as least one centralized pain diagnosis coded in the subject's electronic health record within one year of insomnia diagnosis. A total of 26,804 patients were included in the analysis. Mean age was 66.84 years (SD 8.79); 66% of patients (n=17,687) were female. Overall, 92.1% of patients (n=24,683) carried >=1 centralized pain diagnosis, 5.6% of patients (n=1,505) carried a diagnosis of insomnia, and 2.3% (n=616) had both [95% CI 2.1,2.5]. Of older adults with insomnia, 29% (95% CI 27, 31) also carried a centralized pain diagnosis. Of older adults with centralized pain, 2.4% (95% CI 2.3, 2.6) also carried an insomnia diagnosis. Compared to older adults with insomnia alone, those with both insomnia and centralized pain were more likely to be female (p=< 0.001) and older (p=0.014). Insomnia and centralized pain are highly prevalent in older adults and co-occur frequently in those with insomnia. Older adults with insomnia should be screened for centralized pain. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.1029 igad104.1029 Abstracts Session 3250 (Symposium) AcademicSubjects/SOC02600 PREPARING TO MEET THE NEEDS OF OLDER ADULTS: WORKFORCE, TRAINING, AND EDUCATION ISSUES Caskie Grace Chair 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 309310 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Due to projected growth in the older adult population in the United States, those working in healthcare and education will encounter increasing numbers of older adults. This population shift presents challenges and opportunities for individuals working in these settings to be ready to meet the needs of older adults. In this symposium, we highlight research on several issues critical to preparing the workforce in healthcare and education for older adults' specific needs. Poon's paper addresses geriatric behavioral health workforce needs identified by a survey of licensed behavioral health providers. Several barriers to providing care to older adults are identified by these providers. Rodriguez et al. investigated the clinical practice experiences and challenges from ten years' worth of alumni of the VA Geriatric Scholars program. This training program provides a model for improving clinical practice with older adults. Hollis-Sawyer examines older students' first experiences taking a course in an online teaching setting and provides specific suggestions to maximize their learning environment. Patterson et al. present an extensive scoping review of end-of-life training for medical students that identified several themes that can direct efforts to improve end-of-life care for older adults. Finally, Caskie et al. address health biases and age biases in doctoral psychology trainees' anticipated clinical work with depressed older adult clients of varying health statuses and provide guidance to psychology programs for improving training. This symposium aims to provide those working in healthcare and educational settings with ways to address workforce preparedness to meet the needs of older adults. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.0960 igad104.0960 Abstracts Session 3175 (Symposium) AcademicSubjects/SOC02600 POLICY SERIES: THE MOVING FORWARD NURSING HOME COALITION: NURSING HOME REFORM AND THE RESIDENTS' GOALS, PREFERENCES, AND PRIORITIES McMullen Tara Chair Shippee Tetyana Co-Chair Degenholtz Howard Discussant 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 288288 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract The 2022 National Academies of Sciences, Engineering, and Medicine (NASEM) report called for nursing facilities to provide "care aligned to the individual's goals and preferences." Missing has been an efficient process to uncover the individual's detailed goals, preferences, and priorities (GPPs). GPPs are a care planning process that translates into actionable interventions, supported by quality measurement to determine whether the care provided aligns with those GPPs, and health information technology to collect GPPs efficiently and to determine if the care provided is concordant with the individual's GPPs. A diverse set of experts representing the Moving Forward Nursing Home Quality Coalition are collaborating to develop an integrated approach to these shortcomings and will discuss these issues in detail including new approaches to the identification and documentation of GPPs for use in a modified care planning process, the status of health information technologies (HIT) processes being developed to support these changes and the development of new quality measures. While the Moving Forward Coalition is focused on nursing facilities, the approaches being developed here to improve care and to standardize the vocabulary for GPPs are applicable to all care settings. Three committees from the Moving Forward Nursing Home Coalition will present work focused on the development of a standardized GPP care planning process to enhance the identification, documentation, communication, and implementation of resident GPPs, the measurement of the care planning process to support process improvement, and the creation of a HIT-enabled process to measure the concordance of care provided with an individual's GPPs. This is a collaborative symposium between the Aging Workforce, Hospital Elder Life Program, Measurement, Statistics, and Research Design, Systems Research in Long Term-Care, and Technology and Aging Interest Groups. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.1633 igad104.1633 Abstracts Session 4285 (Symposium) AcademicSubjects/SOC02600 ETHNICITY IN RESEARCH ON OLDER MIGRANTS: HOW THE SCHOLARSHIP CONCEPTUALIZES IT AND WHERE WE NEED TO HEAD Torres Sandra Uppsala University, Uppsala, Uppsala Lan, Sweden 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 497497 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract A recently completed scoping review of peer-reviewed articles on older ethno-racialized minorities has shown that although conceptual and theoretical advancements have been made in the field of ethnicity and race, the social gerontological literature on these minorities continues to regard ethnicity in essentialist ways, conflates ethnicity with race and seldom operationalizes what these social positions mean to aging and old age. The impact of ethnicity is, in other words, almost always inferred in this research, which is why the field has been deemed to be characterized by data-richness and theory-poorness. Over the past three years, researchers working on the nexus of aging and migration have surveyed the current state of knowledge on older migrants (focusing on migrancy, rather than ethnicity and/ or race). One of these inventories is a meta-analysis of how research on older migrants conceptualizes ethnicity, and the manner in which this social position is presumed to impact on migrants' old aging-related experiences. At stake has also been the assessment of whether this literature differs from the scholarship on older ethno-racialized minorities, and the ways in which that scholarship conceptualizes ethnicity. This presentation offers insight into what this inventory has found out. In focus are the current state of affairs about how ethnicity is approached in research on older migrants, and the launching of a theoretically-informed and empirically-astute research agenda for the study of ethnicity in gerontology. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.1490 igad104.1490 Abstracts Session 4130 (Paper) Factors Impacting Health in Older Adults AcademicSubjects/SOC02600 RACE AND SEX DIFFERENCES IN RELATIONS OF DIABETES BIOMARKERS WITH PHYSICAL FUNCTIONING BEFORE DIABETES ONSET Khambaty Tasneem University of Maryland, Baltimore County, Baltimore, Maryland, United States Splain Ashley University of Maryland, Baltimore County, Baltimore, Maryland, United States Katzel Leslie I Baltimore VA Medical Center, Baltimore, Maryland, United States Evans Michele K National Institute on Aging, National Institutes of Health, Baltimore Zonderman Alan B National Institute on Aging, National Institutes of Health, Baltimore Waldestein Shari R University of Maryland, Baltimore County, Baltimore, Maryland, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 453453 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract It remains unclear if declines in physical functioning linked to Type 2 diabetes (T2DM) occur even before T2DM onset. We examined the longitudinal associations of T2DM biomarkers with upper and lower extremity strength among adults without T2DM at baseline. Participants were 1,572 African American (AA) and White adults (M(SD) age at baseline = 47.3 (9.7) years, 55% female, 53% AA) from the Healthy Aging in Neighborhoods of Diversity across the Life Span (HANDLS) study, assessed on up to 3 time points between 2004-2017. Participants provided blood samples for measurement of fasting glucose and glycosylated hemoglobin (HbA1c), and completed dominant and nondominant handgrip strength assessment, and a chair stands task to assess upper and lower extremity strength, respectively. Linear mixed effects regression models estimating relations of HbA1c on age-related change and adjusting for race, sex, literacy, and poverty status revealed significant four-way interactions of HbA1c, race, sex, and age (B = -.2.59, t(2853) = -2.0 p = 0.04), and to a lesser extent of fasting glucose, race, sex, and age (B = -.07, t(2863) = -1.84 p = 0.06) on change in the chair stands task, but not on handgrip strength (ps > 0.29). Among younger AA and White men, and younger White women, increasing HbA1c was related to worse lower extremity strength. However, among AA women, and older White women, increasing HBA1c was related to better lower extremity strength. Our findings suggest differential relations of worse glucose regulation on physical functioning amongst African American and White men and women. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.1149 igad104.1149 Abstracts Session 3370 (Symposium) AcademicSubjects/SOC02600 POSTPENSIONABLE AGE AS A DISTINCT CAREER STAGE Platts Loretta Stockholm University, Stockholm, Sweden Cahill Kevin Boston College, Boston, Massachusetts, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 345345 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract This paper presents a new, two-phase model of the late career. Drawing on life course theory, we assert the importance of age-norms for ordering the timing of people's lives in countries with universal old-age pension systems. Three age boundaries may govern the transition to retirement: social security rules, employment rules and social norms. Upon reaching these boundaries: (1) old-age pension receipt provides a reliable income easing breadwinner pressures, (2) compulsory retirement may push older people out of the workforce, and (3) social expectations encourage participation in leisure rather than paid work. Once old-age pensions ease or eliminate bread-winning pressures, financial necessity no longer drives most of these oldest workers. Further, these working pensioners are defying social conventions calling on them to retire from paid work. Post-pensionable-age or "phase II" jobs tend to be more flexible and rewarding, and less stressful than those held by younger workers. Intriguingly, not only do these workers have quite distinctive motivations to work, they have unique ways of subduing the potential burdens of working. However, most research lumps together workers over pensionable age (in phase II) with workers still in their fifties (in phase I) who are fully exposed to labor market risks. This paper presents theoretical arguments and empirical evidence to support the idea that post-pensionable-age work is a discrete career phase economically, subjectively, and in terms of leverage with employers. It explores likely geographical and socio-economic limits to this two-phase model of the life course. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.1236 igad104.1236 Abstracts Session 3455 (Symposium) AcademicSubjects/SOC02600 INSIDE PAHPA: A GSA POLICY INTERN'S JOURNEY TO THE INTERSECTION OF POLICY AND PREPAREDNESS Thompson Alisha LSU, Baton Rouge, Louisiana, United States Brekke Bailee Miami University, Oxford, Ohio, United States Mu Christina University of South Florida, Tampa, Florida, United States D'Antonio Patricia The Gerontological Society of America, Washington, District of Columbia, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 372372 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Public health and safety are facing increasingly severe threats from natural disasters, infectious diseases, and emergencies caused by human actions, both intentional and unintentional. These incidents now impact a larger number of people and cover broader geographical areas compared to the past. Chief among those most affected are older people, as highlighted during the COVID-19 pandemic and other crises. Addressing these disparities is crucial, and the federal government plays a pivotal role in tackling this issue. Much of my research up to this point has focused on preparedness among older people for emergencies that threaten public health. My experience as a GSA Summer Policy Intern has significantly influenced my understanding of the relationship between public health emergencies and aging policy. Through witnessing the legislative process at the national level, monitoring resource allocation in the federal budget, and attending Congressional hearings, I gained valuable insights into the complexities of this field. My perspective was further shaped by closely monitoring, synthesizing, and disseminating information about the 2023 Reauthorization of the Pandemic and All-Hazards Preparedness Act (PAHPA). Additionally, I provided valuable feedback on the relevance of this bill to the interests of GSA and contributed to comments on a bipartisan discussion draft related to this legislation. Equipped with this newfound insight and understanding, I am confident that I will be a more effective advocate and scholar in the field of aging policy. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.1338 igad104.1338 Abstracts Session 3555 (Symposium) AcademicSubjects/SOC02600 IMPROVING COGNITIVE FUNCTION IN THE NEW COHORT BUT ONLY FOR MEN. FINDINGS FROM THE KYOTANGO CENTENARIAN STUDY Gondo Yasuyuki Osaka University, Suita, Osaka, Japan Zhang Xinyu Osaka University, Suita, Osaka, Japan 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 405405 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract The Kyotango Centenarian Cohort Study was established with the aim of tracing long-term changes in the overall functioning of centenarians. This study started in 2014 in Kyotango City. Since then, new centenarians and those who were expected to be 100 years old the following April were invited to the study every year in September. Eligible centenarians were invited by the city, and centenarians and their families agreed to participate to answer questions either by mail or face-to-face interviews, according to their preference. For the non-participants, anonymized living conditions and care need levels were provided by the city. The number of centenarian candidates varied by year (24-55). However, the number of woman centenarians had increased through the 8-year surveyed period (31 and 42 for women, 10 and 9 for men in 2014 and 2021). On average, every year 40 new centenarians were invited and 80% of them participated in the survey. Among the functional variables, cognitive function was estimated by proxies, which had a high correlation with MMSE. No clear improving trend for nursing care level in Japanese long-term care insurance, as measured by activities of daily living and cognitive function rating, was observed. Meanwhile, an improving trend for cognitive function was observed among men but not among women. This might be caused by the gender difference in the survival ratio that frail women were more likely to survive. Future research should investigate possible reasons for a cohort improvement in Japanese centenarian men, and cognitive intervention programs should particularly target women. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.2299 igad104.2299 Abstracts Session 7160 (Poster) Long-Term Care (Hs) AcademicSubjects/SOC02600 THE PREVALENCE AND PREDICTORS OF APATHY AMONG CANADIAN LONG-TERM CARE RESIDENTS: A SECONDARY DATA ANALYSIS Agboji Aderonke University of Northern British Columbia, Prince George, British Columbia, Canada Freeman Shannon University of Northern British Columbia, Prince George, British Columbia, Canada 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 709709 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Apathy, defined as a reduction in interest or motivation to engage in goal directed activities, is a frequent and persistent health concern among persons residing in long term care facilities. Research showed that apathy is associated with rapid cognitive decline, impaired functional ability, and increased mortality risk. To prevent or mitigate the negative impacts of apathy on persons living in long term care facilities, there is need for better understanding of the risk factors associated with it. Therefore, the aim of this study was to determine the prevalence of apathy and its risk factors in a large sample of Canadian long-term care residents (N=332,454). We performed cross-sectional analysis of data from MDS 2.0 assessments completed between 2015 and 2019 fiscal year. Results from descriptive and inferential analyses showed that apathy was more prevalent among persons aged 65 or younger and speak English. The strongest predictors of apathy were province of residence (OR 4.09 (CI 2.99-5.59) followed by resistance to care (OR 2.43 CI 2.38-2.49), conflict with family (OR 2.30 CI 2.2-2.4), and insomnia (OR 2.16 CI 2.11-2.2). These findings highlight the important role of environmental contextual factors including the physical and social environment as well as personal factors in the development of or recovery from apathy. Strategies for combating apathy in long term care facilities should take into account the individual, institutional and provincial variances. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.2776 igad104.2776 Abstracts Session 7640 (Poster) Community-Based Research AcademicSubjects/SOC02600 AGING-RELATED IMMUNE CELLS PHENOTYPES AND ALL-CAUSE MORTALITY IN THE FRAMINGHAM HEART STUDY Ragab Ahmed A Y Boston University School of Public Health, Boston, Massachusetts, United States Doyle Margaret University of Vermont, Burlington, Vermont, United States Chen Jiachen Boston University School of Public Health, Boston, Massachusetts, United States Fang Yuan Binghamton University, Binghamton, New York, United States Lunetta Kathryn Boston University School of Public Health, Boston, Massachusetts, United States Murabito Joanne Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 862862 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Almost 2 billion people will likely be above the age of 60 by 2050. Aging is a process that is intrinsically complicated. One of the measures for immune system senescence is aging related immune cells phenotypes (ARIP)s. Besides CD8/CD4 ratio, new immunosenescence phenotypes have been proposed. The associations between ARIPs and all-cause mortality during long-term follow up is understudied. We profiled immune cells using flow cytometry and prospectively investigated ten different ARIPs, namely, CD4+CD27-, CD4+CD28-CD27-, CD8+CD27-, CD8+CD28-CD27-, CD4+/CD8+ ratio, CD4+(Tnaive/(T Central Memory (Tcm)+T Effector Memory (Tem)+T Effector (Teff)), CD8+ (Tnaive/(Tcm+Tem+Teff)), Granzyme B+CD8/Granzyme B+CD4 ratio, CD8+ Tc17/Treg ratio and CD4+ Th17/Treg ratio in relation to survival outcome among 990 dementia-free Framingham Heart Study (FHS) Offspring cohort participants who attended the seventh exam (1998-2001, mean age 62 years, range 40-88, 52% female). Cox proportional hazards regression models adjusting for age and sex with robust variance to account for family correlation were used to test for association between the ARIPs and hazard of death. During up to 20 years of follow up, the survival rate was 66%. Higher CD8+ Tc17/Treg ratio was significantly associated with better survival (HR:0.82 [0.7-0.94], p< 0.001). Higher CD4+ Th17/Treg ratio and CD4/CD8 ratio were also nominally associated with lower risk of death (HR:0.87, [0.75-0.97], p=0.01 and HR 0.9, [0.79-0.99], p=0.04, respectively). Other ARIPs were unassociated with all-cause mortality. We conclude that further investigation of the CD8+Tc17/Treg and CD4+ Th17/Treg ratios as ARIP biomarkers for risk of all-cause mortality is justified. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.2742 igad104.2742 Abstracts Session 7620 (Poster) Alzheimer's Disease and Dementia (Hs) AcademicSubjects/SOC02600 ANALYSIS OF CONVERSATIONAL ENTRAINMENT AMONG OLDER PERSONS WITH ADRD AND UNIMPAIRED ADULTS Williams Christine Florida Atlantic University, Boca Raton, Florida, United States McKinley Joseph Florida Atlantic University, Boca Raton, Florida, United States Cooper Charles Florida Atlantic University, Boca Raton, Florida, United States Erdol Nurgun Florida Atlantic University, Boca Raton, Florida, United States Beetle Christopher Florida Atlantic university, Boca Raton, Florida, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 850851 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Social isolation threatens the health of older adults, particularly those with Alzheimer's disease and related dementias (ADRD). Our research uses measures of behavioral coordination to quantify the entrainment of an individual's behavior to the collective dynamics of a group to which they belong, aiming to identify useful strategies to reduce social isolation for persons with ADRD in therapeutic group contexts. The present study is based on data collected during 27, 30-minute group therapy sessions conducted biweekly via WebEx by staff facilitators at a university-affiliated Memory and Wellness Center (MWC) in 2021, when CoViD-19 restrictions limited patients' access to existing, in-person day programs. We study conversational entrainment among facilitators and participants in the recorded sessions using previously identified measures such as speech duration; voiced and voiceless interval durations; variations in pitch, intensity, and syllabic rate; and turn breaks. We present preliminary results identifying dynamical characteristics of sessions showing greater and lesser degrees of group social engagement before discussing possible strategies facilitators could use to enhance social coordination within therapy groups. The mental health benefits of professionally facilitated supportive group discussions for older adults with ADRD are well-accepted. Measuring conversational entrainment has the potential to provide quantitative evidence of cognitive benefits for persons with ADRD, and to help shape a therapeutic environment tailored to the needs of this vulnerable population. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.3613 igad104.3613 Late Breaking Abstracts Session 9030 (Poster) Late Breaking Poster Session IV AcademicSubjects/SOC02600 SYMPTOM BURDEN, POSITIVE AFFECT AND RESILIENCY IN OLDER ADULTS EXPERIENCING NORMAL AGING Anctil Reid Massachusetts General Hospital, Boston, Massachusetts, United States Chang Angela Suffolk University, Boston, Massachusetts, United States Mitchell Calli Massachusetts General Hospital, Boston, Massachusetts, United States Traeger Lara Massachusetts General Hospital, Boston, Massachusetts, United States Park Elyse Massachusetts General Hospital, Boston, Massachusetts, United States Ahmad Zeba Massachusetts General Hospital, Boston, Massachusetts, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 11251126 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Older adults (age>=65) with multimorbid disease burden may be at chronic risk for bothersome symptoms, which can consequently reduce positive affect (e.g., feelings of excitement and enthusiasm). However, we hypothesized that individuals with more resiliency (the ability to "bounce back" from distress) may experience positive affect despite symptom burden. We conducted secondary analysis of baseline self-report survey data (collected between 8/2023-10/2023) from a prospective study of resiliency in older adults residing in nine continuing care retirement communities (CCRCs) across the U.S. Eligible participants lived independently in CCRCs and scored >11/15 on the five-minute Montreal Cognitive Assessment. Surveys assessed symptom burden (Condensed Memorial Symptom Assessment Scale), resiliency (Current Experience Scale), and positive affect (Positive and Negative Affect Schedule-Positive Affect). Bivariate correlations and multiple linear regression evaluated associations of symptom burden and resiliency with positive affect. Participants (M age =81, SD=5.6) were predominantly White (96%) and female (75%). Greater symptom burden correlated with lower positive affect (r=-.295, p<.001) and lower resiliency (r=-2.56, p<.001). In a multiple regression model, lower symptom burden (b = -.136, p=.003) and more resiliency (b=.626, p<.001) were independently associated with greater positive affect. The overall model accounted for 45.4% of variance in positive affect (F(2, 284) =117.198, p<.001). Lower symptom burden and more resiliency contributed to more positive affect among older adults in senior living communities. Because resiliency and positive affect are both potentially modifiable targets for intervention, longitudinal study and psychosocial interventions should explore the effects of increased resiliency on positive affect and general well-being over time. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.1061 igad104.1061 Abstracts Session 3280 (Symposium) AcademicSubjects/SOC02600 ACTIVE ENGAGEMENT AFTER RETIREMENT Yeung Dannii Chair Chung Edwin Co-Chair 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 319319 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Retirement has been shown to accelerate the declines in physical and mental health (Dave et al., 2008) and cognitive functioning (Celidoni et al., 2017; Xue et al., 2018) due to the identity disruption and removal of a cognitively simulating environment after leaving the workforce. This necessitates a need to systematically uncover factors that could potentially buffer the negative impacts brought by retirement. This symposium aims to identify the types of self-initiated activities that can maintain post-retirement well-being through research conducted in Hong Kong and Japan. Specifically, the first paper from Chung reveals that retirees engaging in postretirement work exhibit lower life satisfaction but higher cognitive functioning than those without work. Similarly, the second paper from Katagiri also shows that work has negative impacts on life satisfaction, but such effect is buffered by civic participation. The third paper from Ho suggests that the beneficial effects of ICT use on personal mastery is more prevalent in retirees than in non-retirees. The fourth paper from Lin discloses that participation in cognitively demanding volunteering activities is associated with better cognitive and psychological functioning. These four presentations unveil various types of post-retirement activities that are beneficial to retirees, including re-engagement in the workforce, the use of technology for leisure and financial purposes, and participation in cognitively stimulating volunteering. Given that most of the pre-retirees do not have much planning on social life arrangement, findings of this symposium provide practical implications to improve psychological adjustment to this critical life event. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.1205 igad104.1205 Abstracts Session 3420 (Symposium) AcademicSubjects/SOC02600 COGNITIVE BEHAVIORAL AND VIRTUAL REALITY TREATMENTS FOR INSOMNIA (CBTI AND IVR): OFF-LABEL IMPACT ON COGNITION McCrae Christina University of South Florida, Tampa, Florida, United States Stearns Melanie University of South Florida, Tampa, Florida, United States Curtis Ashley University of South Florida, Tampa, Florida, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 363363 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Chronic insomnia (CI) is common in mid-to-late life and associated with hyperarousal and impaired cognition and mood. CBTi improves sleep and may also improve cognition, arousal and mood but evidence for these latter outcomes is limited. We examined these outcomes across 3 studies with different delivery platforms (telehealth, digital, VR), dosages (2 sessions, 4 sessions), and (primarily) mid-to-older CI populations (fibromyalgia, dementia caregivers). Study 1 compared 8-week CBTi vs sleep hygiene in women with fibromyalgia (n=43, Mage=44.45). Study 2 piloted 4-session web-based CBTi in caregivers (n=5, Mage=62.40). Study 3 piloted 4-session iVR (n=18, Mage=36.45). Participants completed 2-week daily diaries pre/post treatment (sleep onset latency-SOL; wake after sleep onset-WASO; total sleep time-TST) and Insomnia Severity Index-ISI. Other measures included: study 1(arousal/heart rate variability-RMSDNN), studies 1 and 3(Wisconsin Card Sort Test-WCST, Stroop), study 2(Cognitive Failures Questionnaire-CFQ, Beck Depression Inventory-BDI-II, Perceived Stress Scale). Group x time interactions (study 1) and within-group pre/post differences were examined. CBTi improved sleep across studies (ps<.05). Study 1 found and study 3 trended toward improved cognitive flexibility (WCST %perseverative errors-t(14)=2.65, p=.019 and t(10)=1.76, p=.055, respectively). Study 1 found improved attention and processing speed [Stroop reaction time(RT)-congruent trials-t(14)=2.59, p=.023], inhibition (Stroop RT-incongruent trials-t(14)=2.43, p=.031), and arousal [increased RMSDNN; F(1,41)=4.87, p=.03]. Study 2 found improved subjective cognition-CFQ (t(4)=2.44, p=.04), arousal-RMSDNN (t(4)=2.09, p=.05), and depression-BDI-II (t(4)=2.89, p=.02). CBTi improved sleep, cognition, arousal and mood in mid-to-older CI populations. Research using randomization, active controls, and follow-ups is needed to delineate temporality and explore sleep's mechanistic contribution to cognition and other "off-label" outcomes. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.0982 igad104.0982 Abstracts Session 3195 (Symposium) AcademicSubjects/SOC02600 ASSOCIATIONS BETWEEN COGNITIVE RESOURCES AND EMOTION REGULATION TACTICS IN AN ADULT LIFESPAN SAMPLE Wolfe Hannah Northeastern University, Boston, Massachusetts, United States DiGirolamo Marissa Northeastern University, Boston, Massachusetts, United States Isaacowitz Derek Northeastern University, Boston, Massachusetts, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 294295 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract The current study investigated how trait-level cognitive capacity relates to emotion regulation tactic preferences in everyday life in adulthood and old age. 51 younger adults (ages 18-39), 53 middle-aged adults (ages 40-59), and 55 older adults (ages 60+) completed measures of working memory and verbal fluency, as well as 21 days of experience sampling. On each survey, participants indicated if they had regulated since the last survey and if so, what emotion regulation strategies they used and how they implemented that strategy through specific emotion regulation tactics. Each strategy laid out by the process model (situation selection, situation modification, attentional deployment, reappraisal, response modulation) could be implemented in three specific ways (called "tactics"): positivity-upregulating, negativity-downregulating, or negativity-upregulating. For example, a person may indicate they used situation selection and then would be asked whether they chose to (a) seek out a positive situation, (b) leave a negative situation, and/or (c) enter a negative situation. Acceptance was also included as a fourth tactic type but was not categorized under any strategy. Proportions of tactics used in each instance was calculated. Acceptance use was significantly negatively correlated with working memory performance; however, this association appeared to be driven primarily by middle-aged adults. Negativity-downregulation was positively correlated with numerous cognitive capacity measures in middle-aged adults. In sum, individual differences in cognitive resources appear to play the strongest role in tactic preferences in midlife rather than old age. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.2006 igad104.2006 Abstracts Session 5125 (Paper) Health and Social Interventions II AcademicSubjects/SOC02600 RURAL OLDER ADULTS' VIEWS OF DEPRESCRIBING AND NONPHARMACOLOGICAL METHODS IN PAIN TREATMENT Noh Hyunjin University of Alabama, Tuscaloosa, Alabama, United States Jeong Haelim The University of Alabama, Tuscaloosa, Alabama, United States Kan Denise University of Alabama, Tuscaloosa, Alabama, United States Lee Lewis School of Social Work, The University of Alabama, Tuscalossa, Alabama, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 615615 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Proper pain management is essential to quality of life. Due to the risks of harmful drug interactions, there has been an increasing effort to reduce medication that may be harmful or ineffective (i.e., deprescribing) and to promote non-medication based (i.e., non-pharmacological) strategies in pain management. The purpose of this qualitative study is to understand the views of deprescribing and non-pharmacological methods in pain management among community-dwelling older adults with multiple chronic health conditions. Eligibility criteria included: 65+, Alabama resident living outside of nursing homes, cognitively intact, have two or more chronic health conditions and chronic pain, and take medications for their health conditions including pain medications. Participants were recruited through the Area Agency on Aging across the state of Alabama as well as other community venues serving older adults. Individual, open-ended interviews were conducted by phone to explore their concerns about medications, their views of deprescribing and using non-pharmacological pain management as well as their needs in doing so. Thematic analysis of the interview data revealed various barriers and needs: concerns about various side effects while also worrying about missing out benefits from the medications if reduced or stopped, uncertainty or skepticism toward non-pharmacological pain treatment, lacking financial and logistical access to non-pharmacological options, and lack of knowledge about available non-pharmacological options and their benefits. These findings have implications for future education and advocacy efforts to promote older adults' knowledge and self-efficacy so that they can consider deprescribing and non-pharmacological methods in managing their pain. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.0702 igad104.0702 Abstracts Session 2305 (Symposium) AcademicSubjects/SOC02600 TREATMENT OF PAIN DURING THE ACUTE CARE STAY FOR PATIENTS LIVING WITH DEMENTIA Boltz Marie Pennsylvania State University, State College, Pennsylvania, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 212213 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract The purpose of this study was to describe pain among hospitalized patients living with dementia, the use of pharmacologic and nonpharmacologic treatment, and to compare treatments among those with and without pain. Data from the first 365 participants in the FFC-AC-EIT study was used. The mean age of participants was 83 (SD=5), the majority was female (65%) and White (67%). Controlling for treatment, between admission to discharge there was a significant decrease in pain from 36% having pain on admission to 31% at discharge (F=5.30, p=.02). At discharge 125 (30%) had pain and 8 (6%) of individuals with pain received no nonpharmacological or pharmacological treatments during the hospital stay. The most frequently used pharmacological intervention was acetaminophen (52%), then tramadol (8%). Comfort measures (49%), physical activity (46%), and communication (38%) were the most common nonpharmacologic approaches. Between those with and without pain there was no difference in use of pharmacologic interventions (F = .38, p =.54) and there was less use of nonpharmacological treatments for those with pain (F=10.24, p=.002). The majority of patients living with dementia were treated for pain, but an ongoing focus is needed to assure optimal pain management for all patients. More attention to use of and evaluation of effectiveness of pharmacologic and nonpharmacologic treatments alone or together are needed for hospitalized patients living with dementia. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.1756 igad104.1756 Abstracts Session 4415 (Symposium) AcademicSubjects/SOC02600 DEVELOPING A TOUCHSCREEN COMMUNICATION DEVICE TO EMPOWER PEOPLE WITH DEMENTIA AND THEIR CAREGIVERS Brown Ellen Nicole Wertheim College of Nursing and Health Sciences, Florida International University, Miami, Florida, United States Ruggiano Nicole University of Alabama, Hoover, Alabama, United States Allala Sai Florida International University, Miami, Florida, United States Puche Gabriel Florida International University, Miami, Florida, United States Roberts Lisa Florida International University, Miami, Florida, United States Framil C Florida International University, Miami, Florida, United States Munoz Mariateresa Florida International University, Miami, Florida, United States Hough Monica Florida International University, Miami, Florida, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 535535 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract People living with dementia (PLWD) often experience communication deficits that create frustration and challenges to caregiving and clinical care for this population. It also constrains person-centered care. To address communication challenges, an interdisciplinary team developed a mobile communication app that promotes communication by PLWDs about their daily care preferences and experiences. This app, My Person Assisted Touchscreen Interface (My PATI), empowers PLWDs and their caregivers by supporting communication with a fully-customizable platform. This platform allows the PLWD to express preferences for daily activities, such as preferred foods and clothing options. It also enables the PLWD to express their experiences relevant to symptoms of pain, depression, and sleep quality. This presentation will describe a multi-phase Quality Implementation Framework that the research team has applied in developing My PATI to maximize its potential for being adopted into the home and residential care settings and used by multiple caregivers. The presentation will include the My PATI implementation video and foundational research: qualitative interviews with PLWDs, caregivers of PLWD, alpha and beta testing with dyads of caregivers and PLWDs, and extensive assessment and development planning with clinicians, geriatric researchers, computer scientists, and a graphic artist to inform My PATI functions and design. The presentation will also describe the designs of future pilot testing and randomized control trial studies that are planned for 2024. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.2792 igad104.2792 Abstracts Session 7660 (Poster) Frailty in Aging AcademicSubjects/SOC02600 EVALUATING A TRANSITIONAL CARE PROGRAM FOR OLDER ADULTS WITH FRAILTY BETWEEN HOSPITAL AND HOME Lee Ji Yeon Yonsei University, Seoul, Republic of Korea Cho Eunhee Yonsei University College of Nursing, Seoul, Republic of Korea Kim Sue Yonsei University, Seoul, Republic of Korea Kim Gwang Suk Yonsei University College of Nursing, Seoul, Republic of Korea Lee Kyung Hee Yonsei University, Seoul, Republic of Korea Kim Chang Oh Yonsei University, Seoul, Republic of Korea 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 867867 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Older adults with frailty experience numerous health problems even after hospital discharge, highlighting the necessity of continued intervention until their recovery and return to daily routines. This mixed methods research (i.e., quantitative and qualitative studies) aimed to evaluate the effectiveness of a transitional care program developed for older adults with frailty during the transition from hospital to home and how it was helpful. From June to December 2021, 32 older adults with frailty were enrolled in a randomized controlled trial at a university-affiliated hospital in Korea. They were allocated to either an intervention group (n=16) or a control group (n=16) according to a random number sequence. The intervention group received a 12-week transitional care program that included inpatient care, structured discharge, and follow-up interventions (e.g., home visits and phone follow-ups); the control group received usual care only. At 12 weeks, program participants (eight frail older adults and eight family caregivers) had interviews for the qualitative research. The results showed that the intervention group had a higher score in knowledge readiness (p=.046) at discharge, empowerment (p=.032), and connectedness at four weeks (p=.037); community resource utilization (p <.001) and emergency room visit rate (p=.049) at 12 weeks; and improvement in depression (p <.001), family interaction (p=.045), and subjective health status (p=.002) over time. Participants described the program as a supportive, connected, timely, and personalized intervention. Overall, the study demonstrated that the transitional care program effectively improved the health outcomes of older adults with frailty and facilitated a safe transition between hospital and home. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.0695 igad104.0695 Abstracts Session 2300 (Paper) Alzheimer's Disease and Related Dementias and Health Care AcademicSubjects/SOC02600 DISPARITIES IN CONTINUITY OF CARE AND USE OF ANNUAL WELLNESS VISITS AMONG OLDER AMERICANS WITH DEMENTIA Mahmoudi Elham University of Michigan Medical School, Ann Arbor, Michigan, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 210211 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Working on a risk-adjusted, prospective, capitated payment system, Medicare Advantage (MA) plans are incentivized to offer more efficient and coordinated care than traditional Medicare (TM). This study has two aims: (1) compare the continuity of care and use of annual wellness visits between MA and TM enrollees with Alzheimer's disease and related dementia (ADRD), and (2) examine Hispanic-White and Black-White disparities in the continuity of care and annual wellness visits by comparing MA with TM enrollees with ADRD. We used a 20% random sample of TM and MA insurance claims (2018-2019). Participants included individuals 65+, with a diagnosis of ADRD, and two years of continuous enrollment in TM (n=129,177) or MA (n=119,130). We used the Bice-Boxerman Continuity of Care Index to measure continuity of care. Generalized linear models were applied. TM lowered the odds of Black and Hispanic individuals having an annual wellness visit [OR=.80 (95% CI:.79-.82)]. Black and Hispanic TM enrollees had lower odds of annual wellness visits as compared to their Black and Hispanic MA counterparts [OR=.83 (95% CI:78-.88) and OR=.88 (95% CI:.83-.94)], respectively. White, Black, and Hispanic MA enrollees had higher continuity of care than their counterparts in TM (27.4 vs. 24.9; 28.9 vs. 28.1; 32.1 vs. 30.1, respectively). MA enrollees with ADRD had higher care continuity than their TM counterparts. Compared to TM, MA increased the odds of annual wellness visits and reduced Hispanic-White disparity in annual wellness visits. Findings from this study can inform policies promoting preventive and equitable care for patients with ADRD. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.2058 igad104.2058 Abstracts Session 5180 (Biological Sciences Invited Symposium) AcademicSubjects/SOC02600 BIOLOGICAL AGING AND APOE STATUS REWIRE INTER-OMIC ASSOCIATIONS RELATED TO BIOENERGETICS IN HUMANS Rappaport Noa Institute for Systems Biology, Seattle, Washington, United States Ellis Dylan Institute for Systems Biology, Seattle, Washington, United States Watanabe Kengo Institute for Systems Biology, Seattle, Washington, United States Wilmanski Tomasz Institute for Systems Biology, Seattle, Washington, United States Hood Leroy Institute for Systems Biology, Seattle, Washington, United States Price Nathan Thorne HealthTech, New York City, New York, United States Funk Cory Institute for Systems Biology, Seattle, Washington, United States Baloni Priyanka Purdue University, West Lafayette, Indiana, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 631632 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Apolipoprotein E (APOE) modifies human aging, with the e2 and e4 alleles being among the strongest genetic predictors of longevity and Alzheimer's disease, respectively. However, the mechanisms of APOE's impact on aging and cognition remain largely uncharacterized. In this study, we analyzed inter-omic context-dependent association patterns across APOE genotype, sex, and health in an undiagnosed cohort of 1950 individuals. We hypothesized that APOE genotypes would show variation in energy metabolites tied to previously-validated metrics of 'biological aging', a modifiable health metric based on blood biomarkers. Our analysis identified top APOE-associated metabolites as diacylglycerols, including linoleoyl-arachidonoyl-glycerols, similarly increased in APOE compared to e3-homozygotes. Male e2-carriers and biologically-older males displayed a similar increase in associations between insulin resistance and bioenergetic metabolites including pyruvate, glucose, gluconate, and lactate, a trend which was validated in an independent cohort of TwinsUK females. These results provide an atlas of APOE allele-rewired associations and support the involvement of bioenergetic pathways in mediating APOE impact on longevity and AD risk, suggesting targets for enhancing healthspan via lifestyle-modifications or drug-repurposing. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.0726 igad104.0726 Abstracts Session 2330 (Symposium) AcademicSubjects/SOC02600 PERCEIVED BARRIERS AND SOCIOCULTURAL FACTORS OF ADVANCE CARE PLANNING AMONG CHINESE AMERICAN OLDER ADULTS Zhang Peiyuan University of Maryland, Baltimore, Baltimore, Maryland, United States Sun Fei Michigan State University, East Lansing, Michigan, United States Hirsch Jen Michigan State University, East Lansing, Michigan, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 220220 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Despite documented benefits of advance care planning (ACP), persistent racial and ethnic disparities exist in ACP engagement. This study, guided by a social ecological model, examined perceived barriers and sociocultural factors associated with informal ACP conversations among Chinese American older adults. A purposive sample of 281 community-dwelling older Chinese Americans aged 55 years or older in Arizona and Maryland completed a survey in 2018. The average age of participants was 77.8 (SD = 9.4) and the average number of years living in the U.S. was 24.9 years (SD = 13.4). Most participants were first-generation immigrants (94.7%) and reported Chinese as their primary language (91.8%). About 26.5% of participants had ACP conversations with family. Hierarchical logistic regression results suggest that more perceived barriers were associated with lower odds of ACP conversations (OR = 0.87, p < 0.01). Sociocultural factors were associated with greater odds of ACP conversations, including more years in the U.S. (OR = 1.04, p = 0.02) and English language proficiency (OR = 11.85, p = 0.02). Social support had a significant moderation effect (b = -.01, p < 0.01), indicating a larger effect of perceived barriers on ACP conversations among those with lower social support. Findings highlighted the importance of language services, translated informational materials, and social support in facilitating ACP discussions among Chinese American older adults. Community-based ACP facilitators who have both language skills and cultural competence may be particularly beneficial in engaging this population. Effective ways to reduce barriers to ACP at various levels are needed. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.3650 igad104.3650 Late Breaking Abstracts Session 9030 (Poster) Late Breaking Poster Session IV AcademicSubjects/SOC02600 THE MEDIATION EFFECT OF SOCIAL SUPPORT BETWEEN DEPRESSIVE SYMPTOMS AND LONELINESS IN OLDER ADULTS WITH DIABETES Cho Emma University of Pennsylvania, Philadelphia, Pennsylvania, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 11371137 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract The purpose of this study was to examine the relationship between depressive symptoms and loneliness in older adults with diabetes, and to explore the mediating role of social support in this association. This study was developed as a secondary data analysis using data from the National Social Life, Health, and Aging Project in the USA. The sample consisted of 407 older adults aged 50 to 93 years (mean = 64.76, SD=9.03; 50.9% male; 60% married and white). A multi-item survey questionnaire was used to assess loneliness, social support, and depressive symptoms. Spearman correlation analysis was used to examine the relationship between depressive symptoms, social support, and loneliness; the macro PROCESS on SPSS was used to examine the mediating effects of social support on the association between depressive symptoms and loneliness. Despite the significant correlation between depressive symptoms and social support, social support and loneliness, and depressive symptoms and loneliness, social support did not mediate the influence of depressive symptoms on loneliness. The results of this study support the need for increased awareness of depressive symptoms in older adults with diabetes. Depressive symptoms should be treated to alleviate loneliness, and more research is needed to explore how other social factors influence the relationship between depressive symptoms and loneliness, thereby preventing a synergistic effect of depressive symptoms and loneliness. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.1458 igad104.1458 Abstracts Session 4100 (Symposium) AcademicSubjects/SOC02600 RESPONSE AND RETENTION OF AN ONLINE RESEARCH REGISTRY: ADAPTATIONS MADE FOR RECRUITING ASIAN AMERICANS Yu Kexin Oregon Health & Science University, Portland, Oregon, United States Gothard Sarah Oregon Health & Science University, Portland, Oregon, United States Tupper Emily Oregon Health & Science University, Portland, Oregon, United States Golonka Ona Oregon Health & Science University, Portland, Oregon, United States Lindauer Allison Oregon Health & Science University, Portland, Oregon, United States Pierce Aimee Oregon Health & Science University, Portland, Oregon, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 443443 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Challenges in recruiting research volunteers, especially racial/ethnic minority older adults, have been documented as one of the most significant obstacles to developing effective treatments for Alzheimer's Disease and Related Dementia (ADRD). To address the need for recruitment and raise awareness about ADRD research, the Layton Aging and Alzheimer's Disease Research Center built the online dementia research registry, Alzheimer's Comprehensive Treatment Network of Oregon and Washington (ACTNOW). Individuals aged 18 and above are eligible to join, and prospective participants self-initiated enrollment into the registry. As of March 2023, there are 497 participants (mean age 63.9, 71.6% female, 74% had bachelor's or above degree, 12% residing in a rural area) registered in ACTNOW, with an average follow-up period of 1.8 years (SD=1.2, Max=5). To date, 20 research projects have used ACTNOW for their recruitment, and 93% of registry volunteers have been referred to at least one requesting study. The current ACTNOW participants are predominantly non-Hispanic White (92.4%). We will describe ACTNOW's infrastructure expansion to improve the registry's capacity for engaging and recruiting older Asian American adults with limited English proficiency. We tested the feasibility of using translated informed consent forms and questionnaires, reconciling data collected in different languages with existing data structures, and the effectiveness of community outreach sessions. Developing the capacity to recruit underrepresented populations for future ADRD research projects can be critical to addressing health disparities in dementia awareness, prevention, diagnosis, and care. Standardizing communications with all registry stakeholders, both researchers and volunteers, helps engagement and accurate recruitment efforts. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.1136 igad104.1136 Abstracts Session 3355 (Biological Sciences Invited Symposium) AcademicSubjects/SOC02600 INTERDEPENDENCE OF CYTOSOLIC PROTEOSTASIS, LYSOSOMAL ACIDIFICATION, AND MITOCHONDRIAL FUNCTION Zhou Chuankai (Kai) Buck Institute for Research on Aging, Novato, California, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 341341 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Loss of proteostasis, mitochondrial dysfunction, and lysosome defects are conserved hallmarks of aging. One common consequence of cytosolic proteostasis stress is the formation of protein aggregates that are attached to the mitochondrial outer membrane. It remains unknown why cytosolic protein aggregates are attached to the mitochondria. Here we show that Tom70, a conserved receptor for mitochondrial import, moonlights to nucleate the aggregation of cytosolic proteins through some of the newly synthesized mitochondrial proteins. As the cytosolic accumulation of these aggregate-nucleating mitochondrial proteins causes proteostasis stresses, cells balance their import and synthesis through a TOM70-FKH1/2 pathway to regulate the biogenesis of mitochondrial proteins. The reduction of Tom70 during aging causes age-dependent mitochondrial defects in the biogenesis of mitochondrial proteins and attachment of cytosolic protein aggregates, both of which can be rescued by overexpressing TOM70. Additionally, we observed an unexpected rescue of vacuole/lysosome dysfunction in the cells with mitochondrial function preserved during aging. Further investigation revealed a novel conserved mitochondria-to-vacuole/lysosome axis of organelle crosstalk. Our results estabslih novel connections among different cellular compartments related to three hallmarks of aging. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.1862 igad104.1862 Abstracts Session 4525 (Paper) Age-Friendly Settings of Care for Older Adults AcademicSubjects/SOC02600 REDUCING FINANCIAL TOXICITY IN THE HEALTH CARE SYSTEM USING COST ESTIMATION TOOLS FOR OLDER ADULTS Gelburd Robin FAIR Health, New York City, New York, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 568568 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Financial toxicity the financial, emotional and mental burden patients experience with medical costs that can lead to diminished access to care and reduced quality of life is a growing issue among older adults, family caregivers and care partners. Research suggests that financial health literacy tools may reduce financial toxicity. With support from The John A. Hartford Foundation, FAIR Health undertook an 18-month initiative to advance shared decision making (SDM) among older adults (aged 65 and older) with serious health conditions, and their family caregivers/care partners, through the development and dissemination of decision aids that combine clinical and cost information with resources and educational content; these tools are offered for free to consumers on fairhealthconsumer.org and to healthcare providers on fairhealthprovider.org. This presentation will discuss salient findings from the initiative, as detailed in the brief, Advancing Shared Decision Making among Older Adults with Serious Health Conditions: Lessons from FAIR Health's Grant-Funded Initiative. Feedback from older patients, caregivers/care partners and providers revealed the demand and need for financial health literacy tools that provide cost information and underscored key insights that included: (1) Healthcare costs, billing and lack of transparency in the healthcare system are sources of frustration; (2) Barriers to SDM include low health literacy and poor access to devices; and (3) SDM is viewed by many as a vehicle for patient empowerment. The session will offer a unique insight into how these findings can be used to usher in a new paradigm of healthcare and retool clinical practice and medical education. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.0730 igad104.0730 Abstracts Session 2335 (Biological Sciences Invited Symposium) AcademicSubjects/SOC02600 BLUEPRINT TO TARGET THE SPINAL CORD MOTOR CIRCUITRY TO PRESERVE AND RESTORE MOBILITY IN OLD AGE Valdez Gregorio Brown University, Providence, Rhode Island, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 221222 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Spinal motor neurons are central for the initiation and modulation of all voluntary movements. Within the spinal cord, motor neurons form tens of thousands of excitatory (glutamatergic and cholinergic) and inhibitory (GABAergic and glycinergic) synapses along their dendritic arbor and soma. These synapses contain the information required to execute fine and complex motor commands and are together referred to as the motor circuitry. Once activated, motor neurons drive muscle contraction by releasing neurotransmitters from their axon terminals at neuromuscular junctions (NMJs). Thus, either the death of motor neurons or their disconnection from other neurons are skeletal muscles during aging would undoubtedly compromise motor function. We will show that motor neurons do not die in old female and male mice, rhesus monkeys, and humans. Instead, these neurons selectively and progressively shed excitatory synaptic inputs throughout the soma and dendritic arbor during aging. Thus, aged motor neurons contain a motor circuitry with a reduced ratio of excitatory to inhibitory synapses that may be responsible for the diminished ability to activate motor neurons to commence movements. Additionally, we will show that aged motor neurons present with aberrant changes in genes and molecular pathways with roles in glia-mediated synaptic pruning, inflammation, axonal regeneration, and oxidative stress. I will bring these findings together to suggest that motor neurons at a minimum contribute to the loss of their own synapses with advancing age and discuss possible avenues for therapeutic intervention. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.1647 igad104.1647 Abstracts Session 4300 (Paper) Health Disparities II AcademicSubjects/SOC02600 PREMATURE MORTALITY IN LGBT VERSUS NON-LGBT VETERANS: THE ROLE OF HEALTH RISK FACTORS AND SOCIAL DETERMINANTS OF HEALTH Beaudreau Sherry VA Palo Alto/ Stanford University School of Medicine, Palo Alto, California, United States Lutz Julie VA Palo Alto Health Care System, Palo Alto, California, United States Otero Marcela Max-Plank Institute for Social Law and Social Policy, Munich, Bayern, Germany Warren Allison Yale School of Medicine, New Haven, Connecticut, United States Goulet Joseph Yale School of Medicine, New Haven, Connecticut, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 501501 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Lesbian, Gay, Bisexual, and Transgender (LGBT) adults experience substantially higher rates of mental health conditions and other health risk factors than non-LGBT adults, but there is limited reseach on how these conditions increase risk for premature mortality. The current study examined this issue among middle-aged and older Veterans ages 40-99 who used Veterans Administration healthcare services from 01OCT2009 to 30SEP2019 (N = 845,122). Earlier age of death by suicide, overdose, or all-causes was hypothesized for LGBT (n = 675,639 ) vs. non-LGBT (n = 675,639) Veterans, and health factors and social determinants of health were predicted as key risk factors of earlier age of mortality. As hypothesized, LGBT Veterans had significantly higher rates of death by suicide, overdose, and all-causes among younger age groups than non-LGBT Veterans. Adjusted risk ratios indicate a significant contribution of mental health conditions (e.g., anxiety/depression), medical comorbidity, pain, smoking history, and military sexual trauma accounting for differential mortality rates by age in LGBT and non-LGBT participants. Social determinants of health, such racial/ethnic minority status and housing instability, were also significant contributors. Findings suggest the need for Whole Health interventions for LGBT Veterans to manage multiple health risk factors contributing to increased mortality risk. Suicide prevention is critical for the many middle-aged and older adults who die from suicide each year, and for LGBT Veterans especially, beginning targeted suicide prevention efforts earlier in middle age may prevent suicide deaths in later life. Lastly, findings implicate subgroups of Veterans who may particularly benefit from outreach and services. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.2674 igad104.2674 Abstracts Session 7550 (Poster) Disasters, Emergencies, and Covid-19 AcademicSubjects/SOC02600 THE IMPACTS OF AGE AND PREPARATION INFORMATION ON PREPAREDNESS FOR PANDEMIC: A LATENT CLASS ANALYSIS Chen Zhirui The University of Alabama at Birmingham, Birmingham, Alabama, United States Cong Zhen The University of Alabama at Birmingham, Birmingham, Alabama, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 829829 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract This study examined the age differences in perceived and actual preparedness for a pandemic, as well as the moderating effect of preparation information. Data used was from 2021 FEMA National Household Survey (N = 6,305). Latent class analysis was first conducted to explore the typologies of the information respondents received about how to prepare for a pandemic based on eight indicators (e.g., basic survival, planning/preparation, testing, vaccines). With the adjustment of sample weights, four latent classes were identified: class 1 "insufficient information", class 2 "information emphasizing disaster preparedness", class 3 "information emphasizing disease preparedness", and class 4 "comprehensive information". Subsequently, the results of logistic regression and Poisson regression using sample weights showed that compared to those aged 60 and older, people aged 18-39 and aged 40-59 tended to perceive a lower level of preparedness but were more likely to engage in actual preparedness activities for a pandemic. Relative to those in "insufficient information" class, people in "information emphasizing disease preparedness" class and "comprehensive information" class were more likely to perceive a higher level of preparedness and take actual preparations for a pandemic. In terms of the interactions between age and preparation information, the gap narrowed between people aged over 60 and their younger counterparts in taking actual preparations if they were in "comprehensive information" class. These findings highlighted the age patterns in pandemic preparedness and the impacts of different preparation information strategies, which provided imperative implications for disaster preparedness education and communication campaigns. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.2210 igad104.2210 Abstracts Session 7080 (Poster) Technology: Older Adult Interface and Use AcademicSubjects/SOC02600 VESTA: A SMARTPHONE-BASED ASSESSMENT OF MODERN FINANCIAL CAPACITY FOR OLDER ADULTS Van Vleet Samuel Miami University, Oxford, Ohio, United States Griffin Rebekah University of Texas at Tyler, Tyler, Texas, United States Mallender William University of Texas at Tyler, Tyler, Texas, United States Fontanese Matthew University of Texas at Tyler, Tyler, Texas, United States Sakai Haru The University of Texas at Tyler, Tyler, Texas, United States Savage Blake University of Texas at Tyler, Tyler, Texas, United States Coldiron Allyson University of Texas at Tyler, Tyler, Texas, United States Barnett Michael University of Texas at Tyler, Tyler, Texas, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 680680 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Older adults are often targeted by financial scammers who exploit people unfamiliar with financial technologies and who may struggle to identifying fraudulent activity. Financial technologies have undergone significant changes in recent decades, yet financial capacity measures often do not reflect this shift. There is a clear need for innovating the measurement of financial capacity, particularly among older adults. VESTA (Virtual Economic Simulation and Trust Assessment) is a novel smartphone application that measures older adults' susceptibility to different forms of financial exploitation. VESTA plays out like a smartphone game in which the user furnishes a virtual household. As the user conducts these virtual transactions, they are tasked with spending within a budget, monitoring bank charges, disclosing personal information securely, and determining whether incoming messages (i.e., texts, emails, and voicemail messages) are fraudulent or legitimate. The fraudulent charges and messages include contextual clues that mirror real-life scams. VESTA was designed to assess the user's ability to manage money, identify incorrect information, and judge who to trust independent of memory ability. VESTA therefore purposefully targets severely overlooked pitfalls that impact older adults' ability to identify fraudulent activity. Furthermore, VESTA utilizes a user-friendly, accessible design with large font and complete navigation with the simple press of a finger. As the migration of financial management and communication continues towards predominantly digital landscapes, this research and diagnostic tool represents an evolution of existing measures of financial capacity for an at-risk aging population. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.1390 igad104.1390 Abstracts Session 4025 (Paper) Family Caregiving (Hs) AcademicSubjects/SOC02600 UNPAID CAREGIVERS' PROCESS OF COLLABORATING DURING OLDER ADULT HOSPITAL TO HOME TRANSITIONS Liebzeit Daniel The University of Iowa, Iowa City, Iowa, United States Geiger Olivia The University of Iowa, Iowa City, Iowa, United States Jaboob Saida The University of Iowa, Iowa City, Iowa, United States Bjornson Samantha The University of Iowa, Iowa City, Iowa, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 421421 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Unpaid/family caregivers often provide support critical to older adult hospital to home transitions, but commonly lack time and preparation for their role. There is limited evidence regarding important collaboration and resources for caregivers during the transition. The objective of this grounded theory study was to examine caregivers' process of collaborating with others during older adult hospital to home transitions. Interviews were conducted with unpaid caregivers of adults aged 60 and older and recently discharged from a medical/surgical unit at a large Midwestern teaching hospital, were audio-recorded, and transcribed verbatim. Data were analyzed using open, axial, and selective coding. Caregiver participants (N = 16) included spouses (n = 8), friends (n = 4), children (n = 3), and siblings (n = 1) of an older adult transitioning from hospital to home, were mostly female (n=14), and all were white, non-Hispanic. A conceptual model was developed which illustrates participants' process of collaborating with a caregiving team, providers, networks, and other resources to support themselves and their older person. The process began with the participants taking on and identifying their role, and ultimately led to either supporting their older person's progress towards independence or providing long-term caregiver support. Conditions, including finances, caregiver health, expectations, proximity, and availability, impacted the collaborative process. Consequences varied based on participants' approach to caregiving, such a team versus individual approach. Implications include opportunities to promote active engagement of caregivers in the transition process and facilitation of a team-based approach to supporting the older person and caregivers. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.0111 igad104.0111 Abstracts Session 1105 (Symposium) AcademicSubjects/SOC02600 HOW OFTEN AND WHY DO PEOPLE MANAGE THEIR EMOTIONS?: EMOTION REGULATION IN HEALTHY AGING AND MILD COGNITIVE IMPAIRMENT Springstein Tabea Washington University in St. Louis, St. Louis, Missouri, United States English Tammy Washington University in St. Louis, St. Louis, Missouri, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 3333 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Prominent theories of adult development suggest that individuals increasingly prioritize emotional goals and social relationships as they grow older. Accordingly, older adults are expected to invest more in maintaining their emotional well-being compared to younger adults. Prior work suggests that older adults may accomplish this goal by structuring their lives in ways that reduce the need to manage unwanted emotion. We tested the hypotheses that (1) older adults regulate their emotions less often in daily life compared to younger adults, and (2) when emotion regulation occurs, older adults are relatively more motivated by pro-hedonic and social concerns. Using experience sampling (7x/day for 9 days), we assessed whether emotion regulation frequency and motives differ between younger adults (N = 70), cognitively normal older adults (N = 88), and older adults with mild cognitive impairment (MCI; N = 60). We found that older adults with and without MCI regulated their emotions less frequently than younger adults, even when controlling for mean levels of positive and negative emotional experience. However, there were largely no group differences in emotion regulation motives (i.e., why people wanted to manage their emotions). Future work is needed to explore how age-related differences in life contexts might contribute to less need for emotion regulation in relatively older adults. Less frequent regulation could be beneficial in terms of helping older adults preserve their more limited cognitive resources. The findings regarding motives add to growing research on aging which suggest maintenance or similarity in many emotion regulation processes across adulthood. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.1613 igad104.1613 Abstracts Session 4260 (Paper) Epidemiology and Aging AcademicSubjects/SOC02600 DEVELOPMENTAL ORIGINS OF EXCEPTIONAL HEALTH AND SURVIVAL: A FOUR-GENERATION COHORT STUDY Keys Matthew University of Southern Denmark, Odense, Syddanmark, Denmark Larsen Pernille University of Southern Denmark, Odense, Syddanmark, Denmark Pedersen Dorthe University of Southern Denmark, Odense, Syddanmark, Denmark Kulminski Alexander Duke University, Durham, North Carolina, United States Feitosa Mary Washington University School of Medicine, St. Louis, Missouri, United States Wojczynski Mary Washington University School of Medicine, St. Louis, Missouri, United States Christensen Kaare University of Southern Denmark, Odense, Syddanmark, Denmark 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 491491 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Little is known about the early life health trajectories associated with longevity, due to the length of follow-up required for such studies. In the Long Life Family Study (LLFS) we have identified 659 Danish long-lived sibships and their descendants across three generations and followed them through national civil and health registries. We have previously shown lower adult mortality and morbidity in both offspring and grandchildren generations. Here we compared perinatal, infant, and maternal health outcomes of third-generation grandchildren (n = 5637) and also fourth-generation great-grandchildren (14,908) born into these long-lived families between 1973-2018, to matched controls from the general population. Hazard ratios (HRs) and odds ratios (ORs) were estimated by Cox proportional hazards and conditional logistic regression models. A general pattern of reduced risk was observed in the grandchildren across a range of perinatal and infant health outcomes, most notably in infant mortality (HR = 0.53, 95% CI [0.36, 0.77]), preterm birth (OR = 0.82, [0.72, 0.93]), and low birth weight (OR = 0.83, [0.76, 0.90]). These associations were robust to further adjustment for parental education levels. Negligible infant survival advantage was observed in the great-grandchildren (HR = 0.90, [0.70, 1.17]). However, there were signals of benefit across some other perinatal outcomes, although much fewer and weaker in magnitude than in the grandchildren. Our findings suggest that phenotypic longevity may have developmental origins as early as the perinatal period, and that this effect persists over at least three generations. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.2435 igad104.2435 Abstracts Session 7330 (Poster) Mental and Biobehavioral Health AcademicSubjects/SOC02600 DEPRESSION AND LONELINESS IN BLACK WOMEN WITH HYPERTENSION: A SYSTEMATIC LITERATURE REVIEW Hutto Lashawn George Washington University, Washington, District of Columbia, United States Odlum Michelle The George Washington University, Washington, District of Columbia, United States Dowling Maritza George Washington University, Washington, District of COlumbia, United States Theeke Laurie The George Washington University, Washington, District of Columbia, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 753753 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Hypertension occurs more frequently in Black women than men. Over 50% of Black women have hypertension, compared to 39% of non-Hispanic white women and 38% of Hispanic women. Black women with hypertension are more likely to report depressive symptoms which are associated with hypertension, a known risk for cardiovascular diseases including myocardial infarction, heart failure, and stroke. This paper presents a synthesis of findings from quantitative studies that measured depression and loneliness in black women with hypertension. The literature search used EbscoHost with the following databases: Medline Complete, Academic Search Complete, Medline, Pub-Med, Scopus, APA PsycArticles, APA PsycINFO, and CINAHL. Twelve articles were included. Loneliness and social isolation are predictive of depression in black women ages 40 and older. The issue is further confounded by cultural norms that include not seeking therapy, discussing symptoms, and displaying vulnerability, leading to loneliness and disconnection. Loneliness is increased in middle age black women who've experienced traumatic events. In an intervention trial, the associations between blood pressure control and living arrangements were examined. black women living alone were reported to have a higher prevalence of uncontrolled blood pressure, cardiovascular events, and mortality compared to those living with others. There are limited studies of loneliness and depression in black women with hypertension. Additional studies are needed that include variables reflective of cultural norms. A culturally sensitive clinical environment that facilitates discussion about feelings of depression and loneliness could be foundational to the development of new more precise interventions for black women with hypertension. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.1101 igad104.1101 Abstracts Session 3320 (Symposium) AcademicSubjects/SOC02600 STRESS AND COPING AMONG NURSING ASSISTANTS AND PERSONAL CARE AIDES IN LONG-TERM CARE Efird-Green Lea University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States Sloane Philip University of North Carolina, Chapel Hill, North Carolina, United States Lathren Christine University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States Perreira Krista University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States Bluth Karen University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States Zimmerman Sheryl University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 330331 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Care in nursing homes and assisted living communities is largely provided by direct caregivers (nursing assistants [NAs] and personal care aides [PCAs]), who are >50% minoritized, 20% immigrant, 90% female, 87% without a college degree, and often in poverty. The well-being of direct caregivers is critical to quality of care, but research aimed at improving well-being is hampered because existing measures of stress and coping translate poorly to their backgrounds and work-related experience. To address this gap, we designed and conducted research aimed at describing the range of coping approaches used to address work-related stress, gathering data on a diverse sample of 391 direct caregivers from 9 nursing homes and 4 assisted living communities in 3 states, of which 75% were racially or ethnically minoritized and 21% were immigrant - mirroring the national workforce. Results indicated that 78% of respondents often felt stressed at work, with 30% screening positive for depression and 28% for anxiety, with some caregivers experiencing both (21%). However, working with residents and their families, while stressful (76%), was considered less stressful than workload (90%) and lack of support (83%); in fact, 89% of caregivers said that caring for residents makes them feel appreciated. Coping strategies were diverse, but the most common includedresilient coping (93%), mindfulness (89%), recognizing common humanity (84%), self-kindness (83%), and planning (69%). This presentation will address differences in coping based on demographic characteristics, as well as the relationship between types of coping strategies and reasons for staying in a direct caregiver position. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.2753 igad104.2753 Abstracts Session 7620 (Poster) Alzheimer's Disease and Dementia (Hs) AcademicSubjects/SOC02600 NURSES' PAIN ASSESSMENT AND TREATMENT OUTCOMES IN NURSING HOME RESIDENTS WITH DEMENTIA AND APATHY Liao Yo-Jen Penn State University, State College, Pennsylvania, United States Jao Ying-Ling Pennsylvania State University, State College, Pennsylvania, United States Berish Diane The Pennsylvania State University, University Park, Pennsylvania, United States Boltz Marie Pennsylvania State University, State College, Pennsylvania, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 854854 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Pain is often undermanaged in nursing home (NH) residents with dementia-related apathy; an understanding of related nursing practices is warranted. This descriptive study examined nurses' pain assessment and treatment outcomes in NH residents with dementia and apathy. A two-week chart review of nursing progress notes was extracted. Residents' apathy measured by the Apathy Evaluation Scale (AES) of at least 40 was required. Descriptive and correlation statistical analyses were performed. Seventeen residents were recruited from three NHs; only one NH required daily pain assessment. All residents had pain-related diagnoses (mean=3), with Gastro-esophageal reflux disease and arthritis being the two most common diagnoses. Thirty-four pain-related documentations were identified in progress notes, with 19 pain-related events (e.g., falls, tooth extraction). Among the 19 events, 4 had follow-up documentation of pain management, while the other 15 did not. Among the 34 pain-related documentations, only six described residents' behaviors, and three used a pain assessment tool (Numeric Rating Scale). More frequent as-needed analgesic administration was associated with lower agitation (-0.56, p< 0.05), yet this association was not found in scheduled analgesic use. Residents who reported pain more frequently received more as-needed analgesics (0.63, p< 0.01). Resident apathy levels were not correlated with analgesic prescriptions. Altogether, nurses recognized residents' pain reports. As-needed analgesic use correlated with better pain management outcomes; however, pain-related events were not adequately followed up and/or documented. More research is needed to examine the association between nursing pain management practices and resident outcomes in this population. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.1180 igad104.1180 Abstracts Session 3400 (Symposium) AcademicSubjects/SOC02600 CONNECTING COMMUNITIES: ROLES OF AGING ATTITUDES, PLACE ATTACHMENT, AND PSYCHOLOGICAL WELL-BEING Hou Su-I Chair Liu Li-Fan Co-Chair 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 355355 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract As the global population ages, communities must find innovative ways to support older adults. This symposium focuses on the intersections of aging, community, and culture, particularly emphasizing the importance of place attachment, aging attitudes, psychological well-being, and engagement in promoting healthy aging. Leading experts from social gerontology, psychology, and public health across the globe will explore the complex relationships between aging, community, and culture. Drs. HM Chen from Texas A&M University-Central Texas (TAMCT) and Hou from the University of Central Florida (UCF) from the United States will start the symposium with a systematic literature review on culture and aging in the community among Chinese older adults. Drs. JJ Chen and Liu from the National Cheng-Kung University (NCKU) will examine the mediating effect of psychological place attachment, how older adults perceive their living environments, and (positive versus negative) attitudes towards aging and psychological well-being. Dr. Hou from UCF will further assess aging attitudes (engagement versus enjoyment) among older adults participating in neighborhood lunch versus lifelong learning programs to discuss the implications of tailored aging service development. Finally, Drs. Lin and Fung from The Chinese University of Hong Kong (CUHK) will discuss the association between activity diversity and psychological well-being among community-dwelling older adults in Hong Kong. Through interdisciplinary dialogue and sharing of lessons learned, this global symposium promotes a deeper understanding of the roles of aging attitudes, place attachment, culture, and psychological well-being among older adults to foster innovative approaches to promoting healthy aging and community engagement. This is an Aging Among Asians Interest Group Sponsored Symposium. This is a collaborative symposium between the Aging Among Asians and International Comparisons of Healthy Aging Interest Groups. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.0689 igad104.0689 Abstracts Session 2295 (Symposium) AcademicSubjects/SOC02600 DISASTER PREPAREDNESS OF COMMUNITY-DWELLING OLDER ADULTS Peterson Lindsay University of South Florida, Tampa, Florida, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 209209 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Older adults who depend on others for care are especially vulnerable to harm in a disaster. However, the extent to which they are protected depends on the setting in which they live. State and federal regulations require nursing homes and assisted living communities to have preparedness plans that specifically address the needs of their residents. For older adults living at home, however, protections are far less prescriptive, and in some cases lacking altogether, despite the increasing numbers of disabled older adults receiving care in their homes. In this policy-based study, we examined disaster preparedness for community-dwelling older adults in high-disaster states with high populations of older adults. We found that while many of the states required home-based providers to respond to the post-disaster needs of their older adult clients, few took steps to ensure that before the storm they were prepared. In this study, the state of Florida was an exception, with policies calling for service providers to identify and contact at-risk clients before and after an event. The plan further identifies disaster preparedness as a key component of a livable community. Hurricane Ian struck Fort Myers, Florida, in September 2022. Older adults made up a majority of the 148 killed during and immediately after the storm. Many others lost their homes. In the context of this recent event, we will discuss not only the state and local policies, but the practices that affect the health and well-being of community-dwelling older adults faced with a major disaster. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.1306 igad104.1306 Abstracts Session 3520 (Symposium) AcademicSubjects/SOC02600 LESSONS LEARNED DEVELOPING A NUTRITIONAL ADHERENCE INTERVENTION FOR DEMENTIA PREVENTION: A QUALITATIVE ANALYSIS Sheffler Julia Florida State University College of Medicine, Tallahassee, Florida, United States Patel Juhi Florida State University, Tallahassee, Florida, United States Kiosses Dimitris Weill Cornell Medicine, New York City, New York, United States Naar Sylvie Florida State University, Tallahassee, Florida, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 395395 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Lifestyle interventions show considerable promise in delaying the onset and reducing risk for Alzheimer's disease and related dementias (ADRD). Unfortunately, scalable interventions that address issues of long-term adherence have not been adequately developed or disseminated. Especially important for this effort is iterative evaluation and adaptation of interventions using participant feedback throughout the development process. Using the NIH ORBIT model for behavioral intervention development, our team has established the proof-of-concept (N=9) and pilot tested (N=58) a Mediterranean ketogenic nutrition (MKN) adherence program for older adults at risk for ADRD. This program incorporates motivational interviewing strategies and cognitive behavioral skills training to enhance uptake and long-term adherence to MKN. For each of these pilots, participants completed exit interviews at the conclusion of the 6-week, group intervention and 3-months post-intervention. Qualitative and quantitative data on the acceptability of the program, as well as detailed participant feedback about their experience and recommendations for improvements were collected. While quantitative data demonstrate high acceptability, thematic analysis of qualitative interviews demonstrate a range of recommendations for enhancing and refining important components of the intervention that will be necessary for future scaling and dissemination. We discuss important themes, future directions of this work, and implications for lifestyle intervention development more broadly. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.2344 igad104.2344 Abstracts Session 7230 (Poster) Social Determinants of Health, Equity, and Aging AcademicSubjects/SOC02600 BEHAVIORAL HEALTH PREDICTORS OF PREMATURE MORTALITY IN A BLACK AMERICAN LONGITUDINAL COHORT Green Kerry University of Maryland at College Park, College Park, Maryland, United States Bugbee Brittany University of Maryland School of Public Health, College Park, Maryland, United States Doherty Elaine University of Maryland, College Park, Maryland, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 723724 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Life expectancy among Americans is now the lowest it has been in 15 years. While startling, more alarming are the persistent racial disparities in mortality. Black Americans continue to die at significantly younger ages with Black men living, on average, 7.0 fewer years and Black women living 4.4 fewer years than their White counterparts. To inform intervention strategies and resource allocation, we need a complete understanding of the role that malleable factors, such as substance use and depression early in the life course, play in premature mortality for aging Black Americans. This study illuminates behavioral health factors that can be targeted to eliminate mortality disparities among a longitudinal cohort followed from childhood into their 60s. Utilizing data from the Woodlawn Study, a well-defined neighborhood cohort study of 1,242 Black Americans that began in 1966 (age 6), we examined the predictive value of family history of substance use, adolescent substance use and depression, and young adult substance use and depression. Through 2021 (modal age 61), based on National Death Index reports, 21.6% of the original cohort (n=268) has passed away. The poster will present cause and timing of death by gender and adjusted logistic regression findings showing that depression symptoms as early as adolescence (age 16) predict midlife mortality occurring between ages 32 and 60 (p=.003) and that those diagnosed with depression or a substance use disorder in young adulthood are 61% (p=.025) and 85% (p=.001) more likely to die by age 60. Policy and prevention implications will be presented. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.2417 igad104.2417 Abstracts Session 7300 (Poster) Dementia Care AcademicSubjects/SOC02600 THE ASSOCIATION BETWEEN PSYCHOTROPIC DRUGS AND PHYSICAL FUNCTION IN HOSPITALIZED OLDER ADULTS WITH DEMENTIA Kim Nayeon University of Maryland Baltimore, Baltimore, Maryland, United States Resnick Barbara University of Maryland, Baltimore, Maryland, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 747747 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract The aim of this study was to test if the use of psychotropic medications (antipsychotics, sedatives, antiseizure, antidepressants, and anxiolytics) was associated with physical function in hospitalized older adults living with dementia. This study was a secondary data analysis using baseline data from the Function Focused Care for Acute Care Using the Evidence Integration Triangle (FFC-AC-EIT) study. FFC-AC-EIT is an ongoing randomized controlled trial and this study included the first 290 participants. A path analysis was conducted to test the relationship between psychotropic drugs and physical function while controlling for age, gender, race, comorbidities, cognitive function, neuropsychiatric symptoms of dementia, and pain. Overall, 63.4% of participants took one or more psychotropic drugs, with the most used psychotropic drugs being antidepressants (39%), followed by antiseizure drugs (23.4%), antipsychotics (16.6%), anxiolytics (13.8%), and sedatives (4.1%). No significant association was found between the use of psychotropic medications and physical function. Cognitive function (b=1.489, SE 0.265, p< 0.001), comorbidities (b=-2.680, SE 1.093, p=0.014), and pain (b=-2.837, SE 0.865, p=0.001) were directly associated with physical function. Cognitive function was also indirectly associated with function through pain. The findings support prior research showing a lack of association between the use of psychotropic medications and physical function. Additional research may be needed to investigate the mediating effects of pain between cognition and physical function in older adults with dementia. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.3259 igad104.3259 Late Breaking Abstracts Session 9000 (Poster) Late Breaking Poster Session I AcademicSubjects/SOC02600 DEFINING 'OUTBREAK': ADMINISTRATORS' EXPERIENCES MANAGING COVID-19 AT US NURSING HOMES Brazier Joan Brown University School of Public Health, Providence, Rhode Island, United States Meehan Amy Brown University School of Public Health, Providence, Rhode Island, United States Hawes Courtney Brown University School of Public Health, Providence, Rhode Island, United States Shield Renee Brown University School of Public Health, Providence, Rhode Island, United States Gabois Emily Brown University School of Public Health, Providence, Rhode Island, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 10141014 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract The CDC defines a COVID-19 outbreak as starting with a single positive case of a staff member or resident in a facility and ending after there have been no new cases for 14 days. According to a report from the U.S. Government Accountability Office, 94% of nursing homes in the U.S. experienced multiple COVID-19 outbreaks, resulting in a reported 1.66 million residents and 1.64 million staff members with confirmed COVID-19 as of July 2023. Research has shown that COVID-19 outbreaks froze new admissions and caused significant financial strain. This qualitative study aimed to examine how COVID-19 outbreaks were managed in U.S. nursing homes. 156 interviews were conducted with nursing home administrators from 40 facilities across the U.S. between July 2020-December 2021. Two major themes emerged from thematic analysis: 1) the definition of "outbreak" as a single individual testing positive with COVID-19 was inconsistently communicated to nursing home administrators at the start of the pandemic; and 2) administrator self-reports of COVID-19 outbreaks at their facilities indicated that many endured multiple outbreaks which were long-lasting (greater than 1 month). As policy makers and industry experts review policies around managing nursing home viral outbreaks, they should consider the emerging infection control strategies from the pandemic which successfully prevented the spread of COVID-19 and update the response to an 'outbreak' such that infection control mitigation measures are effective without causing restrictions that are detrimental to resident well being or nursing home financial hardship. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.3306 igad104.3306 Late Breaking Abstracts Session 9010 (Poster) Late Breaking Poster Session II AcademicSubjects/SOC02600 EPISTASIS ASSOCIATION STUDY TO IDENTIFY NETWORK HUB GENES IN ALZHEIMER'S DISEASE AND RELATED DEMENTIAS Evans Luke University of Colorado Boulder, Boulder, Colorado, United States Reynolds Chandra University of Colorado Boulder, Boulder, Colorado, United States Hoeffer Charles University of Colorado Boulder, Boulder, Colorado, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 10291029 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Despite recent advances in understanding ADRD genetic risk, the vast majority of the genetic variance of AD/ADRD risk remains unexplained by identified loci such as APOE or the polygenic signal. One unexplored reservoir of genetic effects is interactions among genes (epistasis), which could identify key and novel molecular pathways, networks, and specific cell types in which the ADRD genetic risk is manifest. We tested all pairwise gene-gene interactions using our recently-developed transcriptome-wide interaction study method on ADRD in the UKBiobank. While no individual epistatic association was genome-wide significant (p< 2.56e-10), several approached significance (p< 3e-8). More importantly, we identified three core genes with >10 suggestive epistatic interactions. These include genes with some limited, prior evidence of a role in ADRD etiology, but none that have been identified in single-locus GWAS. In follow-up enrichment analyses of neuronal annotations underlying the interaction associations, we found genes intolerant to protein truncating mutations (PI), and those expressed specifically in endothelial cells, excitatory neurons in the prefrontal cortex , neuronal stem cells, and PI excitatory dentate gyrus cells to be nominally enriched (p< 0.05) in interaction associations with ADRD using prefrontal cortex imputed expression. Together, these suggest that we can uncover novel aspects of AD biology through these interaction associations and identify genes that may play a key role in integrating signals of AD risk. We anticipate identifying additional core genes and pathways as we integrate other larger and more diverse datasets. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.1864 igad104.1864 Abstracts Session 4530 (Paper) Outcomes of Covid-19 AcademicSubjects/SOC02600 ANTI-ASIAN RACISM AMONG OLDER KOREAN AMERICANS DURING THE COVID-19 PANDEMIC Kwon Soonhyung Rutgers, the State University of New Jersey, Savoy, Illinois, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 569569 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background Hate crimes in the U.S. targeting adults of Asian descent have sharply increased during the COVID-19 pandemic. Korean Americans experience the highest level of everyday racism (37.5%), followed by Chinese (15.2%) and Vietnamese during the pandemic (Jung et al., 2021). Moreover, perceived discrimination in older Korean Americans is significantly related to a greater risk for poor mental health (Chau et al., 2018). However, older Korean Americans were likely to experience barriers to mental healthcare services. With this concern in mind, this study explored how older Korean Americans perceived discrimination related to ethnicity/race and coped with adverse mental health during the pandemic. Methods Our study used the thematic analysis of textual data to reconstruct and categorize, engaging in six steps: 1) familiarizing the qualitative data, 2) generating initial codes, 3) searching for themes, 4) reviewing themes, 5) defining and naming themes, and 6) producing a final report. Results This study identified that older Korean Americans (N=18) experienced direct and vicarious racism during the pandemic but felt barriers (limited English proficiency and a lack of accessible resources) to mental healthcare services. Active religious activities ameliorated discrimination-related stress. Some participants tried to solve the stress through wrong behaviors that criticized Chinese Americans. As a result, barriers to mental healthcare were likely to cause secondary discrimination and prejudice against Chinese Americans. Discussion To ameliorate adverse mental health and prevent secondary discrimination, it is essential to identify well-accepted, well-timed, sustainable, and cost-effective therapeutic strategies to alleviate the adverse mental health associated with discrimination-related stress. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.1566 igad104.1566 Abstracts Session 4210 (Symposium) AcademicSubjects/SOC02600 EFFECT OF AMYLOID PET RESULTS DISCLOSURE ON HEALTH-RELATED BEHAVIORS IN PERSONS WITH MILD COGNITIVE IMPAIRMENT Wang Yan School of Nursing University of Pittsburgh, Pittsburgh, Pennsylvania, United States Ren Dianxu University of Pittsburgh, Pittsburgh, Pennsylvania, United States Roberts Scott University of Michigan, Ann Arbor, Michigan, United States Lingler Jennifer University of Pittsburgh, Pittsburgh, Pennsylvania, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 476476 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Mounting evidence supports the clinical utility of amyloid PET. However, whether patients use knowledge of their amyloid status to alter health behaviors remains unclear. We describe health-related actions taken by Mild Cognitive Impairment patients following amyloid PET disclosure (n=34) vs. a comparison group (n=37). Patients were 92% non-Hispanic white, 59% male, 73+-8.61 years old with 16.25+-2.49 years of education. Over 12 months of follow-up, all participants reported at least one behavior change from baseline on a 14-item health behavior questionnaire. Amyloid positive patients reported the most behavior changes (mean=4.67+-1.83) while amyloid negative patients reported the fewest (mean=3.72+-1.58). Across groups, no significant differences were observed in: lifestyle, vitamin/supplement use, stress reduction activities, cognitive stimulation, or advance directive completion. Amyloid negative participants were significantly less likely than controls to consider long-term care insurance (63.6% vs. 89.2%; P=.025), and to endorse changes classified as "other" (36.4% vs. 64.9%; P=0.037). After adjusting for education level, gender, and MMSE, logistic regression showed that amyloid negative patients were 74% less likely than controls to report "other" changes (OR=0.26, 95% CI [0.08, 0.85], P=0.025), and 78% less likely to consider long-term care insurance (OR=0.22, 95% CI [0.06, 0.86], P=0.03). Qualitative analysis of supplemental interviews with scan group participants revealed "other" activities to include changes in employment, driving, and residential status, and engagement in other non-medical activities (pursuing bucket lists and mending strained relationships). Health-related behavior changes following amyloid PET disclosure may differ by scan result and encompass actions to enhance not only cognition but quality of life. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.2841 igad104.2841 Abstracts Session 7700 (Poster) Family Caregiving (Srpp Posters) AcademicSubjects/SOC02600 SOCAL SAVVY CAREGIVER: FOCUS GROUP INSIGHTS Aguilar Iris Florida International University, Miami, Florida, United States Aranda Maria University of Southern California, Los Angeles, California, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 883883 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Dementia due to Alzheimer's disease (AD) is a public health crisis in our nation. More than 1.6 million Californians provide unpaid care for a person with AD. Qualitative data from focus group discussions were obtained from unpaid/informal/family caregivers in a clinical trial testing the efficacy-effectiveness of Savvy Caregiver Express compared to the Savvy Caregiver Program. Objectives: 1) explore class participation motivations, 2) perceived class benefits, and 3) class improvement recommendations. Methods: We randomly selected and invited participants who had completed the class intervention cycle. Focus group subsample (n=25) was 84% female, mean age 54.48 years (28 to 80 years); 36% non-Latino white, 20% Latino, 8% African American, 4% Asian and American/Pacific Islander. 60% cared for a parent (44% mother and 16% father), 16% cared for a spouse/partner, 20% other relatives, and 4% friends. Focus group were transcribed, coded, and themes were created using inductive analysis. Findings: Themes identified for discussion topic #1: seeking to gain knowledge about AD and stages, peer support, and caregiver competence; #2 knowing AD stages, management of meaning, caregiving mastery, and self-care; and #3 audiovisuals improvements, class structure changes, printed materials, and ongoing virtual sessions. Implications: Participation in caregiving classes are critical to the improvement of quality of life for the person with dementia and caregiver. These findings offer actionable changes to improve the transformation of classes and adjust future materials or provide additional resources to help participants fully understand the course and better understand the motivations for increasing engagement with caregivers. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.1611 igad104.1611 Abstracts Session 4255 (Paper) Civic Engagement AcademicSubjects/SOC02600 VOLUNTEERING AND CHANGES IN CARDIOVASCULAR BIOMARKERS: LONGITUDINAL EVIDENCE FROM THE HEALTH AND RETIREMENT STUDY Kim Seoyoun Texas State University, San Marcos, Texas, United States Halvorsen Cal Boston College, Boston, Massachusetts, United States Han Sae Hwang University of Texas at Austin, Austin, Texas, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 490490 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract A growing body of research shows that volunteering is beneficial for those served, the volunteers, and the larger communities. However, major challenges remain that hinder the practical implications for volunteer activity as a public health intervention, including potential selection effects, lack of longitudinal studies that adjust for baseline characteristics, and a paucity of studies that consider multiple physical health outcomes in a single model. Using data from the 2006-2016 waves of the Health and Retirement Study (N=18,847) and an outcome-wide approach, the current paper evaluated if changes in volunteering between 2006/2008 (t0) and 2010/2012 (t1) were associated with seven cardiovascular disease biomarkers four years later (2014/2016, t2). Further, these models were adjusted for demographic factors, socioeconomic status, health behaviors, chronic conditions, baseline biomarkers, and baseline volunteering. Inverse probability treatment weights (IPTW) were included for the selection into volunteering and multiple imputation was conducted for missing data. Compared to non-volunteers, volunteering more than 200 hours a year was associated with a lower risk for clinically high diastolic blood pressure. Increased volunteering effort (change from 1-99 hours at t0 to >100 hours at t1) was associated with a lower likelihood of clinically high systolic and diastolic blood pressure levels. Sustained high volunteering (>100 hours at both t0 and t1) was associated with lower diastolic blood pressure. The current study adds to the evidence of the health benefits of volunteering for adults 50 and older by inferring a potential causal link between high-intensity volunteering and reduced blood pressure. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.0646 igad104.0646 Abstracts Session 2255 (Symposium) AcademicSubjects/SOC02600 DOWNWARD DEMENTIA TREND GOES INTO REVERSE IN ENGLAND AND WALES? ENGLISH LONGITUDINAL STUDY OF AGING 2002-2019 Chen Yuntao University College London, London, England, United Kingdom Bandosz Piotr Division of Prevention Medicine & Education, Medical University of Gdansk, Gdansk, Pomorskie, Poland Stoye George Institute for Fiscal Studies, London, England, United Kingdom Liu Yuyang Sun Yat-sen University, Guangzhou, Guangdong, China (People's Republic) Lobanov-Rostovsky Sophia University College London, London, England, United Kingdom French Eric Faculty of Economics, University of Cambridge, Cambridge, England, United Kingdom Liao Jing Sun Yat-sen University, Guangzhou, Guangdong, China (People's Republic) Brunner Eric University College London, London, England, United Kingdom 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 196196 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Recent evidence suggests dementia incidence rates are declining in high-income countries. However, data for the trend after 2010 are scarce. We examined the temporal trend in England and Wales from 2002-2019, considering bias and non-linearity. We used population-based panel data linked to the mortality register across wave 1 (2002-2003) to wave 9 (2018-2019) of the English Longitudinal Study of Ageing. Uniform standard criteria based on cognitive and functional impairment were used to ascertain incident dementia cases. Crude incidence rates were determined in seven overlapping initially dementia-free sub-cohorts followed over four years. We estimated the sex-adjusted trend of dementia incidence with Cox and multi-state models. Restricted cubic splines allowed for potential non-linearity. 19 806 people were included in the study. Crude dementia incidence declined from 2002 to 2008 (8.7 to 7.4 per 1000 person-years), and increased from 2008 to 2019 (7.4 to 10.3 per 1000 person-years). Adjusting for age and sex, and accounting for missing dementia cases due to death, estimated dementia incidence declined by 28.8% from 2002 to 2008 (incidence rate ratio 0.71, 95% CI 0.58-0.88), and increased by 25.2% from 2008 to 2016 (incidence rate ratio 1.25, 1.03-1.54). The higher education group had a sharper decline of dementia incidence from 2002 to 2008, and a smaller increase after 2008. Dementia incidence may not be declining. There was a rebound after 2008 in England and Wales. If the upward dementia incidence trend continues, along with population ageing, the burden on health and social care may be large. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.2049 igad104.2049 Abstracts Session 5170 (Paper) Assisted Living AcademicSubjects/SOC02600 SOCIAL WORKERS' AND NURSES' VIEWS ON COLLABORATIVE WORK IN A SETTING WITH SKILLED NURSING CARE Kilaberia Tina New York University, New York City, New York, United States Apgar Dawn Seton Hall University, South Orange, New Jersey, United States Padgett Deborah New York University, New York City, New York, United States Wu Bei New York University, New York City, New York, United States Kennedy Teri University of Kansas Medical Center, Kansas City, Kansas, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 629629 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract This study compares social workers' and nurses' views on collaborative work using descriptive and thematic analysis of semi-structured in-depth interviews conducted at an urban retirement and assisted living community including independent living, assisted living, and skilled nursing care in a United States Midwestern city. Social workers (N=11) and nurses (N=12) responded to questions about how they spent their time, with whom (job category) they worked most and least closely, and what constrained collaborative work. Descriptive analysis showed that social workers exercised greater collaborative awareness than nurses and viewed nurses as partners with whom they worked most closely, whereas nurses did not view social workers and non-clinical peers as such. Qualitative analysis showed that social workers were more focused on resident self-determination, advocacy, and requisite care whereas nurses' orientation was directed toward safety, tasks, and clinical outcomes. In terms of collaborative work, the devalued professional identity of social workers was a threat to collaborative work whereas nurses portrayed failures in collaborative work as stemming from individual actions and attributes. Different approaches to collaborative work between social workers and nurses can impede teamwork. Interprofessional training focused on long-term services and supports may help to reconcile disparate approaches and strengthen collaborative work between social workers and nurses. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.1276 igad104.1276 Abstracts Session 3495 (Biological Sciences Invited Symposium) AcademicSubjects/SOC02600 EMERGING MR IMAGING AND SPECTROSCOPY APPLICATIONS FOR AGING RESEARCH IN MODEL ORGANISMS de Cabo Rafael Chair Bouhrara Mustapha Co-Chair 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 385386 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Advances in quantitative magnetic resonance imaging and spectroscopy (MRI/MRS) methodology have enabled probing tissue microstructure and function with exquisite specificity and sensitivity in human and model systems. Using this technology to examine changes in tissue microstructure and function in aging or pathology has the potential to provide a window into the underlying age-related diseases' mechanisms, and to nominate MR biomarkers for longitudinal assessment and intervention. Water molecules within biological tissues undergo interactions with their environment through nuclear relaxation, magnetization transfer, chemical exchange, and diffusion. These processes are sensitive to underlying local tissue properties such as density, microstructure, temperature, acidity, composition, and geometry. Through use of combinations of magnetic fields and radiofrequency pulse formalisms, MRI/MRS provides unique sensitivity and specificity to probe these mechanisms in all biological tissues. Advances in acquisition strategies, hardware designs, computational analyses, and signal modeling have positioned MRI/MRS as powerful emerging noninvasive modalities to studying biological tissue to differentiate normal from abnormal cell-level processes. These techniques are based on multicomponent relaxometry or diffusion, magnetization transfer, high-dimensional imaging or spectroscopy, susceptibility imaging, cerebral functioning, etc. However, their integration in clinical trials and investigations is still limited. This session will provide an overview about these emerging MRI/MRS techniques, their value and application in studying aging. The overarching goal is to generate further interest within the scientific community, disseminate and integrate these mature and unique noninvasive approaches in research settings and routine clinical protocols to advance our understanding of aging processes. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.0943 igad104.0943 Abstracts Session 3155 (Paper) Sex and Gender Differences AcademicSubjects/SOC02600 NINE-YEAR ASSOCIATION OF OPTIMISM AND COGNITIVE FUNCTIONING IN A COHORT OF AGING MEN Marino Victoria Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, United States Kim Samsuk The VA Boston Healthcare System, Boston, Massachusetts, United States Spiro Avron VA Boston Healthcare System, Boston, Massachusetts, United States Lee Lewina Boston University School of Medicine, Boston, Massachusetts, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 283284 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Higher levels of optimism have been linked to better physical and emotional health, and growing evidence suggests optimism may also protect against cognitive impairment and decline. However, our understanding of its prospective associations with cognitive functioning is limited. We examined 9-year associations of optimism with cognitive functioning among 793 men from the VA Normative Aging Study. Optimism was assessed via the Minnesota Multiphasic Personality Inventory-2 in 1986 (baseline: AgeM = 60.1, SD=7.1). Cognitive functioning was measured at participants' earliest cognitive testing occasion between 1993 and 1996. We considered both global cognition (MMSE) and three domains of cognitive functioning: executive function (verbal fluency via Animal Naming Test, working memory via WAIS-R Digit Span Backward), short-term memory (immediate and delayed CERAD Word List Recall), and visuospatial ability (CERAD and VMI spatial copying, NES-2 Pattern Comparison). Analyses used ordinary least squares regression adjusted for childhood socioeconomic status, and demographics and major diseases at baseline. Optimism was not associated with global cognition. However, higher optimism was associated with better verbal fluency (B=0.48, SE=0.19, 95% CI .11-.86, p=.01) and immediate word list recall (B=0.33, SE=0.15, 95% CI .04-.62, p=.02), and weakly associated with delayed word list recall (B=0.14, SE=0.07, 95% CI -.01-.28, p=.06). Optimism was not associated with visuospatial ability or working memory performance. Our findings suggest that optimism could be particularly important for verbally mediated aspects of executive functioning and memory in aging men. Optimism may be a valuable intervention target to promote healthy cognitive aging. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.1456 igad104.1456 Abstracts Session 4095 (Symposium) AcademicSubjects/SOC02600 CONNECTING AGING RURAL VETERANS WITH TELE-GERIATRIC MENTAL HEALTH: REFERRING PROVIDERS' SURVEYED PERSPECTIVE Carlson Chalise VA Palo Alto Health Care System, Palo Alto, California, United States Humber Marika VA Palo Alto Health Care System, Palo Alto, California, United States Trivedi Ranak Stanford University, Stanford, California, United States Peeples Amanda Corporal Michael J. Crescenz VA Medical Center, Philadelphia, Pennsylvania, United States Lloyd Althea VISN 7, Clinical Resource Hub, VA Atlanta Health Care System, Decatur, Georgia, United States Gould Christine VA Palo Alto Health Care System, Palo Alto, California, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 442442 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Providing comprehensive, individualized care to older Veterans with complex needs is particularly challenging in rural areas. Geriatric mental health specialists are scarce but needed for care including psychiatric medication and behavior management, consultation on complex comorbidities, cognition, and caregiver support and education. Tele-geriatric mental health services were initially developed in one VA regional telehealth hub and then expanded to three more regional telehealth hubs. Referring providers (N = 37) to tele-geriatric mental health services during a 1-year period were surveyed via REDCap. Providers came from varied settings in the 4 VA regions with 76% serving rural Veterans. Referring providers included prescribers (N = 26; pharmacists, physicians, physician assistants, nurse practitioners and advanced practice nurses) and non-prescribers (N = 11; psychologists, social workers). Most worked in Patient Aligned Care Teams, mental health clinics, or Community Living Centers and reported geriatric training and comfort with geriatric patients. When asked about their perception of the impact of the services, most providers believed that patients (91.9%) and care teams (94.6%) benefitted from the telehealth services and would recommend the services (94.6%). Most followed through on recommendations (83.7%) and believed the service increased access to geriatric mental health (89.2%). Open-ended feedback included gratefulness for providing care to aging rural Veterans lacking resources. These services are appreciated by providers and may facilitate access to specialized mental health care particularly in rural areas. Having access to specialists to assist with the care of patients with complex needs may ease the care coordination needed by referring providers. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.0377 igad104.0377 Abstracts Session 1370 (Symposium) AcademicSubjects/SOC02600 PHYSICAL RESERVE MEASURES AS PREDICTORS OF RESILIENCE IN OLDER ADULTS UNDERGOING TOTAL KNEE REPLACEMENT Sison Maria Duke University, Durham, North Carolina, United States Sloane Richard Duke University Medical Center, Durham, North Carolina, United States Colon-Emeric Cathleen Duke University, Durham, North Carolina, United States Whitson Heather Duke University, Durham, North Carolina, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 116116 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Measures of physical reserve have been shown to predict resilience following surgery in older adults. The objective of this study was to evaluate the utility of gait speed, hand grip strength, and 3-minute walk distance to predict resilience in older adults scheduled for total knee arthroplasty (TKA), in whom preoperative gait and mobility may be limited by pain or reduced range of motion. We conducted an interim analysis of data from PRIME-KNEE, an ongoing prospective study following participants age >=60 years undergoing TKA recruited from Duke hospitals. We determined the change in self-reported Lower Extremity Physical Activities of Daily Living (LE PADL) score from pre-surgery baseline to 4 months following TKA in 133 participants (mean age = 72, 59% female). Gait speed, hand grip, and 3-minute walk were collected at baseline. A total of 110 (83%) participants exhibited "resilience," defined dichotomously as any improvement in LE PADL score (occurred in 38 participants) or return to a non-disabled state (occurred in 72 participants). Logistic regression analysis adjusted for age and sex revealed that 3-minute walk distance was significantly associated with resilience at 4 months (OR=1.012 [CI 1.002-1.022]) with an area under the curve of 0.634. The presentation will review the implications of these results and present findings with an updated sample, as well as discuss the need for other predictive measures, such as provocative tests (i.e., tests that measure response to an experimental stressor) and biomarkers. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.1997 igad104.1997 Abstracts Session 5115 (Paper) Social Support and Health AcademicSubjects/SOC02600 THE ROLE OF SOCIAL SUPPORT AND SELF-EFFICACY ON HOPEFULNESS IN LOW-INCOME OLDER ADULTS AGED 50 AND OVER Kwon Soonhyung Rutgers, the State University of New Jersey, Savoy, Illinois, United States Benoit Ellen Center for Drug Use and HIV/HCV Research, NYU School of Global Public Health, New York City, New York, United States Windsor Liliane The University of Illinois at Urbana-Champaign, Champaign, Illinois, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 611612 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background Social support and self-efficacy play a significant role in improving positive psychological well-being in marginalized older adults. However, to date, there are few studies on identifying the relationships during the COVID-19 pandemic. We examined the effect of social support and self-efficacy on hopefulness in marginalized low-income older adults during the COVID-19 pandemic. Methods This study used baseline data from a clinical trial designed to increase COVID-19 testing in Essex County, NJ. The dataset involved participants aged 50 and over. We conducted: 1) cross-sectional descriptive/frequency statistics to understand the sociodemographic characteristics, 2) multivariate linear regression to investigate the direct relationships between social support subscales or self-efficacy and hopefulness, and 3) mediation analyses to examine the mediating role of self-efficacy in the relationship between social support and hopefulness. Results After adjusting for covariate variables, social support subscales (emotional/informational social support: b = 0.20, p < 0.05; tangible social support: b = 0.13, p < 0.05; affectionate social support: b = 0.17, p < 0.05; positive social interaction social support: b = 0.15, p < 0.05) and self-efficacy (b = 0.55, p < 0.001) were significantly associated with hopefulness. The indirect effect of social support via self-efficacy was positive and statistically significant (Effect = 0.14, Bootse = 0.04, BootLLCI - BootULCI = 0.06 - 0.23) Conclusion Self-efficacy mediated the relationship between social support and hopefulness in marginalized older adults aged 50 and over. Further research needs to identify the various facets of positive psychological well-being using longitudinal data and larger sample size. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.3214 igad104.3214 Late Breaking Abstracts Session 9000 (Poster) Late Breaking Poster Session I AcademicSubjects/SOC02600 CELLULAR RESILIENCE AND THE AGING HEART: UNDERSTANDING MITOCHONDRIAL INJURY MECHANISMS USING THE BABOON Adekunbi Daniel UT Health San Antonio, San Antonio, Texas, United States Reilly Elizabeth Health Careers High School, San Antonio, Texas, United States Sanchez-Reilly Sandra South Texas Veterans Health Care System, San Antonio, Texas, United States Li Cun Texas Biomedical Research Institute, San Antonio, Texas, United States Nathanielsz Peter Texas Biomedical Research Institute, San Antonio, Texas, United States Cox Laura Wake Forest University Health Sciences, Winston Salem, North Carolina, United States Salmon Adam UT Health San Antonio, San Antonio, Texas, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 10001000 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background Aging-related cardiovascular disease is deadly worldwide. Cardiac aging in non-human primates (NHP), including baboons, is similar to humans, and intrauterine growth restriction animal models (IUGR) have shown to accelerate cardiac aging and foment cardiomyopathies. Objective: To measure and compare basal and metabolically stressed mitochondrial function among cardiac fibroblasts (CF) isolated from control vs. prematurely older (IUGR) baboons. Methods CF were isolated from IUGR and control baboon hearts under standard conditions (25mM Glucose). Additional subgroups were exposed to Metabolic Stress (MS-exposed to 2-hours of low glucose, 1mM). Mitochondrial Oxygen Consumption Rate (OCR) and extracellular acidification rate (ECAR) were measured via Seahorse XFe96 instrument. Results Donor Age: 13.27 - 17.52 years (elderly baboons), Male/Female data combined, n=4-5. OCR was higher in control relative to IUGR among all groups. ATP demand and non-mitochondrial respiration had similar values between control and IUGR. MS impacted CF bioenergetics similarly in control and IUGR. ECAR was higher in MS cells in both control/IUGR. OCR:ECAR ratio was higher in control vs IUGR while MS lowered OCR:ECAR ratio in control to levels comparable to IUGR. Conclusion Higher OCR indicated increased metabolic demands of aging cells depending on glycolysis for survival. MS significantly impaired mitochondrial function across all cardiac cells regardless of aging. IUGR not only accelerated cardiac aging but impaired basal and metabolic response of CF. CF retain metabolic characteristics of their donor status and represent a cardiac aging model to explore mitochondrial injury mechanisms, understand cellular resilience and subsequently develop protective translational interventions. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.2565 igad104.2565 Abstracts Session 7440 (Poster) Family Caregiving: Measures, Methods, and Interventions AcademicSubjects/SOC02600 CREATION OF A FAMILY CAREGIVER NEGOTIATION TRAINING PROGRAM USING ARTIFICIAL INTELLIGENCE Murawski Alaine Northwestern University, Chicago, Illinois, United States Ramirez-Zohfeld Vanessa Northwestern University, Chicago, Illinois, United States Schierer Allie Northwestern University, Chicago, Illinois, United States Ramirez Ana New York University, New York City, New York, United States Mell Johnathan University of Central Florida, Orlando, Florida, United States Brett Jeanne Northwestern University Kellogg School of Management, Chicago, Illinois, United States Lindquist Lee A Northwestern University, Chicago, Illinois, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 794795 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Family caregivers of people with dementia (PWD) experience conflicts as they navigate the healthcare system but do not have adequate training to resolve these disputes. We sought to develop and pilot test an artificial-intelligence negotiation training program, NegotiAge, for family caregivers. With NIH funding [R01AG068421], we convened a team of negotiation experts, geriatrician, social worker, and community-based family caregivers (Illinois/Florida/New York/California). Content matter experts created informational videos to teach negotiation skills. Family caregivers generated dialogue surrounding caregiver conflicts. Computer science experts input generated dialogue into the Interactive Arbitration Guide Online (IAGO) platform to develop avatar-based agents (e.g. sibling, older adult, physician) for caregivers to practice negotiating. Family caregivers review didactic material then access scenarios to negotiate (e.g. physician recommendations, sibling disagrees with care, PWD refusing support). Caregivers negotiate in real-time with avatars designed to act like humans, including emotional and irrational behaviors. Caregivers can use negotiation tactics until either mutual agreement occurs or time expires. Immediate feedback is generated from the responses chosen and tactics to assist with the negotiation skills training. Pilot testing was conducted with family caregivers of PWD (n=12) and showed that the negotiation and conflict resolution training program was feasible and usable for family caregivers. Subjects found the program to present real-world applicability. NegotiAge is an Artificial Intelligence-based Caregiver Negotiation Program, that is usable and feasible for family caregivers to become familiar with navigating conflicts seen in caring for PWD. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.1999 igad104.1999 Abstracts Session 5120 (Symposium) AcademicSubjects/SOC02600 DEVELOPMENT OF A CULTURALLY TAILORED COST MANAGEMENT INTERVENTION INFORMED BY CAREGIVER VOICES Benton Donna University of Southern California, Los Angeles, California, United States Mage Susanna University of Southern California, Los Angeles, California, United States Wilber Kathleen University of Southern California, Los Angeles, California, United States Meyer Kylie Case Western Reserve University, Cleveland, Ohio, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 612612 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Caregivers spend an average of 20% of their annual household income on out-of-pocket caregiving costs. Yet, no evidence-based interventions help family caregivers manage these expenses and financial stressors. Responses to financial strain must be culturally tailored to Latino family caregivers, whose out-of-pocket care costs comprise nearly half their annual household income. This presentation describes the development of the CONFIDENCE Financial Education Intervention, a 5-week psychoeducational intervention informed by the Resourcefulness and Quality of Life Theory and made to address the needs of Latino family caregivers. To ensure CONFIDENCE was responsive to the needs of Latino caregivers, the investigators 1) conducted 11 qualitative in-depth interviews with caregivers to learn about their experiences managing care costs and 2) convened a community advisory council of Latino family caregivers to guide intervention components, content, and delivery. Council recommendations guided multiple intervention modifications. For example, based on these recommendations from the council, the investigator team expanded the intervention's target audience from focusing on women to including caregivers of all genders so families could participate together (familialism). Findings from the interviews and the council overlapped. During interviews, caregivers reported feeling worried about the growth of future caregiving costs increasing; similarly, the council described the importance of helping caregivers understand how costs would change throughout the disease trajectory. Caregiver interviews and the advisory council also emphasized the importance of addressing the needs of middle-income caregivers to prevent future financial adversity. By integrating the caregiver voices, we developed an intervention tailored to meet the needs of Latino families. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.1108 igad104.1108 Abstracts Session 3330 (Symposium) AcademicSubjects/SOC02600 PERFORMANCE OF FUNCTION-FOCUSED CARE BY NURSING STAFF Galik Elizabeth University of Maryland School of Nursing, Baltimore, Maryland, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 332332 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract To help acute care nurses learn to provide function focused care during care interactions the Function Focused Care intervention is implemented on nursing units. The Function Focused Care intervention is based on the Social Ecological Model, Social Cognitive Theory and the Evidence Integration Triangle and includes four components: (1) Development of a stakeholder team; (2) Education; (3) Development of functional care plans; and (4) Mentoring and motivating. Our nurse interventionist provides function focused care education as per the preference of the setting. Following education, direct observation during care interactions is done and the nurse interventionist provides recommendations related to the approach being used or provides positive reinforcement if function focused care is provided. The observation tool used to evaluate function focused care by the nursing staff includes 19 different care interactions (e.g., bathing, dressing, transferring). Guidelines are provided for what is and is not function focused care. In the first four treatment sites, at 2 months post implementation the nurses provided function focused care during 81% of the of care interactions observed, by 6 months this increased to 85% and by 10 months this increased to 88%. There was also a decline in the number of care interactions in which function focused care was not provided. The findings suggest that nurses can provide function focused care even during times of significant shortages and that continued oversight and education can help improve the use of this approach. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.1797 igad104.1797 Abstracts Session 4455 (Symposium) AcademicSubjects/SOC02600 PREFERENCES FOR NEW MODELS OF SOCIAL CARE FOR OLDER PEOPLE IN ENGLAND Walbaum Magdalena London School of Economics and Political Science, London, England, United Kingdom 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 547547 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Ageing and increasing diversity of the population pose challenges for social care provision. England has implemented several initiatives to improve care quality and make it more personalised, informed, and connected. This study aimed to understand the preferences of older people, including those from diverse backgrounds, for different aspects and models of social care, and how they trade-off different features of care. The study included two workstreams with participants aged 50+: 1) A qualitative study that explored preferences across five themes: housing settings, community assets, technology use, provision of care, and control and dignity; 2) A quantitative survey that analysed variations in preferences by demographic, socioeconomic, and needs-related factors. A discrete choice experiment was also conducted to evaluate the strength of preferences for different attributes. Older people value their independence and control over their lives and prioritise access to community resources and social connections. Participants also emphasised the importance of building a positive relationship with their care provider, respecting their sexual identity and personal beliefs to receive good quality care. In this presentation, differences in preferences among demographic, socioeconomic, and ethnic groups will be highlighted, underscoring the need to ensure that care packages align with individual preferences, beliefs, and values and promote equitable access to care, and outcomes. This approach may ensure that older people from diverse backgrounds receive high-quality care that promotes their independence and dignity and produces equitable care outcomes. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.1038 igad104.1038 Abstracts Session 3255 (Symposium) AcademicSubjects/SOC02600 INCLUSIVE AGING AND DIGITAL PLACE-MAKING IN AGETECH: THE INCLUDEAGE PROJECT Sixsmith Judith University of Dundee, Dundee, Scotland, United Kingdom Fang Mei University of Dundee, Dundee, Scotland, United Kingdom 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 312312 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract This presentation will address the challenges of virtual community inclusion for older people, with a focus on seldom-heard and under-served groups, such as those with intellectual and developmental disabilities (IDD) and those who identify as lesbian, gay, bi, trans + (LGBT+). Given that the COVID-19 pandemic has amplified the digital divide, further excluding marginalized social groups, the aim of this ESRC funded IncludeAge Project is to explore how virtual spaces can be made more inclusive to enhance social inclusion and support health equity. The presentation will consist of two key elements. Firstly, current discourses and definitions of 'community' and 'inclusion' in digital spheres will be discussed through findings from a scoping review. Secondly, the presentation will introduce new and innovative ways of digital participatory mapping working alongside older people with IDD and those who identify as part of the LGBT+ community using ArcGIS digital storymapping. This approach offers a unique and powerful way of including under-served groups in the design and development of inclusive AgeTech. The presentation will further highlight the challenges and benefits of digital participation in a post-COVID world, particularly for those who experience exclusion. It will demonstrate the importance of involving under-served groups in the design and development of digital spaces to enhance social inclusion and support health equity. To conclude, we will discuss how these new ideas might be used to shape government policy and organizational practices when it comes to the future of inclusive AgeTech research, design, and development with and for older people. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.0364 igad104.0364 Abstracts Session 1360 (Symposium) AcademicSubjects/SOC02600 DAILY SOCIAL RELATIONSHIP QUALITY, DAILY STRESS, AND SUBJECTIVE COGNITIVE DECLINE AMONG OLDER ADULTS Jang Heejung Clemson University, Clemson, South Carolina, United States Mogle Jacqueline Clemson University, Clemson, South Carolina, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 112112 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Although prior research has shown that social relationships are strongly associated with cognitive function, few studies have explored the link between the quality of daily relationships and subjective cognitive decline (SCD). The present study explores whether the quality of daily relationships is associated with daily stress and how daily stress mediates the relationship between the quality of daily relationships and SCD among older adults. This study uses data from 254 older adults aged 70 or older who completed the Einstein Aging Study. Multilevel mediation analyses were conducted to account for daily measurements nested within individuals. The cognitive change index was used to measure SCD. We tested the indirect effect of daily relationship quality on SCD through daily stress levels. There was a significant positive association between ambivalent (b=.148, p<.001; b=.324, p<.001) and neutral (b=.095, p<.001; b=.297, p<.001) relationships and daily stress levels at both the between-person levels. Between-person daily stress was, in turn, associated with greater SCD (b= .169, p<.05). In particular, there was a significant indirect path from ambivalent relationships to SCD through daily stress. This study contributes to a more detailed understanding of how relationship quality can impact cognition through increased exposure to daily stress. The quality of daily social relationships may be crucial to preserving older adults' cognitive function. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.3345 igad104.3345 Late Breaking Abstracts Session 9010 (Poster) Late Breaking Poster Session II AcademicSubjects/SOC02600 FAILURE TO RECOVER FROM PROACTIVE INTERFERENCE & TRAJECTORY OF CLINICAL DEMENTIA RATING SUM OF BOXES IN AMNESTIC MCI Zheng D Diane University of Miami, Miami, Florida, United States Curiel Rosie University of Miami Miller School of Medicine, Miami, Florida, United States Ortega Alexandra University of Miami Miller School of Medicine, Miami, Florida, United States Crocco Elizabeth University of Miami Miller School of Medicine, Miami, Florida, United States Crenshaw Kiresten University of Miami, Miami, Florida, United States Ramirez Sofia University of Miami, Miami, Florida, United States Ortiz Juliana University of Miami, Miami, Florida, United States Loewenstein David University of Miami Miller School of Medicine, Miami, Florida, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 10401041 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background The Loewenstein-Acevedo Scale for Semantic Interferences and Learning (LASSI-L) has been shown to be sensitive to Alzheimer's Disease (AD) pathology among those with preclinical AD, however, LASSI-L's ability to predict longitudinal cognitive and functional decline of preclinical AD has not been examined. Method We evaluated 97 older adults aged 54-98 who were diagnosed with amnestic mild cognitive impairment (aMCI) at 1Florida Alzheimer's Disease Research Center initial visit. The mean age was 71.9 yr, 51% male, average education 15.7 yr, and mean MMSE score was 28.0. Participants had 3 to 5 visits over a follow-up time as long as 76.7 months. We examined the association of LASSI-L measures on the growth curve trajectory of Clinical Dementia Rating sum of Box (CDRSOB). Results The growth curve model that best fit the CDR sum of box trajectory is a linear form and included the fixed and random effect of intercept and slope of time. After adjusting for age, gender, education, Hopkins Verbal Learning Test (HVLT) delayed recall and LASSI-L maximum storage capacity, worse performance on LASSI-L measures of vulnerability to proactive semantic interference (B2 cued recall, b=-0.093, se 0.004, p-0.004) and semantic intrusion (B2 cued intrusions, b=0.053, se 0.023, p=0.02) were statistically significant in predicting a steeper slope on the trajectory of decline in CDRSOB. Conclusions The LASSI-L measures reflecting failure to recover from proactive interference and associated intrusions predicted the rate of cognitive/functional decline over time in amnestic MCI and demonstrated the utility of LASSI-L's longitudinal prediction of prodromal AD. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.0936 igad104.0936 Abstracts Session 3150 (Award Lecture) AcademicSubjects/SOC02600 PRESIDENTIAL SYMPOSIUM: EDUCATIONAL NEEDS AND STRATEGIES ACROSS GSA: BUILDING BRIDGES WITHIN THE SOCIETY Newsham Tina Chair Montepare Joann Discussant 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 281281 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Across GSA member groups, we teach, train, and mentor in a variety of ways and for different purposes. Education is a tie that connects us across the Society. In this AGHE Presidential Symposium, representatives from the different GSA membership sections will discuss the educational needs of their members and share strategies they employ with their students, employees, mentees, and others to ensure the best preparation of the workforce. Researchers, care providers, educators, advocates, and others must be well-prepared to address the opportunities and demands of an aging society. Tamar Shovali, from Behavioral and Social Sciences, will present empirically supported approaches to intergenerational communication and training to foster relationships between aging individuals and their communities. Biological Sciences member LaDora Thompson will highlight current educational efforts in translating geroscience discoveries into new medical advances. Health Sciences member Matt Peterson will present strategies, challenges and opportunities learned from a currently funded health sciences mentoring program. Social Research, Policy, and Practice member Nancy Kusmaul will discuss efforts to shape policy to enhance geriatrics and gerontology education. AGHE Chair Joann Montepare will serve as discussant, exploring how AGHE can build more bridges by integrating educational efforts in several unique ways. Collectively, presenters in this session will highlight the connections and opportunities for collaboration across GSA member groups. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.1939 igad104.1939 Abstracts Session 5060 (Biological Sciences Invited Symposium) AcademicSubjects/SOC02600 THE CELL "SURFACEOME": A STRATEGY TO TARGET SENESCENT CELLS IN VIVO Banarjee Reema National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States Dey Amit National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States Nyunt Thedoe National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States Gregg Jordan National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States Tsitsipatis Dimitrios National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States Herman Allison National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States Gorospe Myriam National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States Basisty Nathan National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 592592 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Senescent cell accumulation drives aging and related pathologies including metabolic disorders and neurodegeneration, and their selective elimination is a promising therapeutic approach to treat multiple diseases of aging in humans. However, developing drugs to eliminate senescent cells requires specific biomarkers to selectively identify and target these cells in vivo. In this study, we have performed a comprehensive and quantitative proteomic profiling of surface proteomes (surfaceomes) of senescent cells to identify potential senescence biomarker candidates in human tissues. We induced senescence using ionizing radiation in a variety of cell types including lung fibroblasts, monocytes, vascular smooth muscle cells, aortic endothelial cells and preadipocytes. Senescence was validated using a panel of canonical markers including reduced proliferation, increased senescence-associated b-galactosidase activity, and increased expression of p21, p16, IL6, and others. The cell surface proteome was enriched using an optimized surface biotinylation approach (Glyco-cell surface capture) followed by data-independent acquisition (DIA) LC-MS/MS analysis on a Q-Exactive HF Orbitrap mass spectrometer. Our analysis revealed novel cell surface targets that were further validated by flow cytometry and immunohistochemistry. These results provide clinically useful information for establishing biomarkers and therapeutic targets to aid in the translation of senescence-targeted therapies to treat age-associated diseases. pmc |
Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igad104.1273 igad104.1273 Abstracts Session 3490 (Paper) AcademicSubjects/SOC02600 SARCOPENIA AND MOBILITY DYSFUNCTION AS INDICATORS OF INCREASED ADRD RISK IN ASYMPTOMATIC DISEASE Tolea Magdalena University of Miami Miller School of Medicine, Miami, Florida, United States Besser Lilah University of Miami, Miami, Florida, United States Galvin James University of Miami, Miami, Florida, United States 12 2023 21 12 2023 21 12 2023 7 Suppl 1 Program Abstracts from The GSA 2023 Annual Scientific Meeting, "Building Bridges > Catalyzing Research > Empowering All Ages" 384385 (c) The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Sarcopenia, the age-related loss of muscle mass and function, affects up to 30% of older adults. In addition to being an established component of frailty and predictor of mobility dysfunction, sarcopenia is associated with cognitive decline and increased risk of cognitive impairment, with ~70% individuals with late-stage dementia having sarcopenia. In this study, we investigated whether sarcopenia differentiates risk among 141 community-dwelling, older adults who were healthy controls (HC) or had mild cognitive impairment (MCI) (65% female; mean Age=70+-11yr; mean Educ=16+-3yr). Using the Brain Health Platform (BHP) developed at the Comprehensive Center for Brain Health, we categorized participants based on measures of resilience, vulnerability, cognitive performance as: Low-risk HC (36.9%); High-risk HC (12.8%), and MCI (50.4%). Amyloid positivity increased across risk groups (20% in Low-risk HC; 33.3% in High-risk HC; 39.1% in MCI). Prevalence of sarcopenia was 26.7% and increased by ADRD risk (12.2% vs 18.8% vs 39.1%, p=0.004). The MCI group had lower flexibility compared to both the low-risk (p=0.024) and high-risk HC (p=0.039) groups. Timed Up and Go (TUG) score increased with risk group (p< 0.001MCI vs Low-risk HC; p=0.005MCI vs High-risk HC). Both mobility measures (i.e., flexibility, TUG) showed good discrimination for MCI vs Low-risk HC [AUC=0.77flexibility; AUC=0.78TUG] as well as for MCI vs High-risk HC [AUC=0.71flexibility; AUC=0.73TUG). Findings suggest that sarcopenia and other markers of mobility dysfunction have the potential to identify asymptomatic individuals at increased risk of ADRD, who could benefit from early intervention. pmc |
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