Shreshth Gandhi
commited on
Commit
·
6f23458
1
Parent(s):
c2d674f
Update README.md
Browse files- README.md +24 -126
- dataset_size_comparison.png +0 -0
README.md
CHANGED
@@ -6,140 +6,38 @@ size_categories:
|
|
6 |
- 10M<n<100M
|
7 |
---
|
8 |
|
9 |
-
#
|
10 |
|
11 |
-
|
|
|
|
|
|
|
|
|
12 |
|
13 |
-
|
|
|
14 |
|
15 |
-
|
|
|
16 |
|
17 |
-
### Dataset Description
|
18 |
|
19 |
-
|
20 |
|
|
|
21 |
|
22 |
|
23 |
-
- **Curated by:** [More Information Needed]
|
24 |
-
- **Funded by [optional]:** [More Information Needed]
|
25 |
-
- **Shared by [optional]:** [More Information Needed]
|
26 |
-
- **Language(s) (NLP):** [More Information Needed]
|
27 |
-
- **License:** [More Information Needed]
|
28 |
|
29 |
-
### Dataset Sources [optional]
|
30 |
|
31 |
-
<!-- Provide the basic links for the dataset. -->
|
32 |
|
33 |
-
|
34 |
-
|
35 |
-
|
36 |
-
|
37 |
-
|
38 |
-
|
39 |
-
|
40 |
-
|
41 |
-
|
42 |
-
|
43 |
-
|
44 |
-
|
45 |
-
[More Information Needed]
|
46 |
-
|
47 |
-
### Out-of-Scope Use
|
48 |
-
|
49 |
-
<!-- This section addresses misuse, malicious use, and uses that the dataset will not work well for. -->
|
50 |
-
|
51 |
-
[More Information Needed]
|
52 |
-
|
53 |
-
## Dataset Structure
|
54 |
-
|
55 |
-
<!-- This section provides a description of the dataset fields, and additional information about the dataset structure such as criteria used to create the splits, relationships between data points, etc. -->
|
56 |
-
|
57 |
-
[More Information Needed]
|
58 |
-
|
59 |
-
## Dataset Creation
|
60 |
-
|
61 |
-
### Curation Rationale
|
62 |
-
|
63 |
-
<!-- Motivation for the creation of this dataset. -->
|
64 |
-
|
65 |
-
[More Information Needed]
|
66 |
-
|
67 |
-
### Source Data
|
68 |
-
|
69 |
-
<!-- This section describes the source data (e.g. news text and headlines, social media posts, translated sentences, ...). -->
|
70 |
-
|
71 |
-
#### Data Collection and Processing
|
72 |
-
|
73 |
-
<!-- This section describes the data collection and processing process such as data selection criteria, filtering and normalization methods, tools and libraries used, etc. -->
|
74 |
-
|
75 |
-
[More Information Needed]
|
76 |
-
|
77 |
-
#### Who are the source data producers?
|
78 |
-
|
79 |
-
<!-- This section describes the people or systems who originally created the data. It should also include self-reported demographic or identity information for the source data creators if this information is available. -->
|
80 |
-
|
81 |
-
[More Information Needed]
|
82 |
-
|
83 |
-
### Annotations [optional]
|
84 |
-
|
85 |
-
<!-- If the dataset contains annotations which are not part of the initial data collection, use this section to describe them. -->
|
86 |
-
|
87 |
-
#### Annotation process
|
88 |
-
|
89 |
-
<!-- This section describes the annotation process such as annotation tools used in the process, the amount of data annotated, annotation guidelines provided to the annotators, interannotator statistics, annotation validation, etc. -->
|
90 |
-
|
91 |
-
[More Information Needed]
|
92 |
-
|
93 |
-
#### Who are the annotators?
|
94 |
-
|
95 |
-
<!-- This section describes the people or systems who created the annotations. -->
|
96 |
-
|
97 |
-
[More Information Needed]
|
98 |
-
|
99 |
-
#### Personal and Sensitive Information
|
100 |
-
|
101 |
-
<!-- State whether the dataset contains data that might be considered personal, sensitive, or private (e.g., data that reveals addresses, uniquely identifiable names or aliases, racial or ethnic origins, sexual orientations, religious beliefs, political opinions, financial or health data, etc.). If efforts were made to anonymize the data, describe the anonymization process. -->
|
102 |
-
|
103 |
-
[More Information Needed]
|
104 |
-
|
105 |
-
## Bias, Risks, and Limitations
|
106 |
-
|
107 |
-
<!-- This section is meant to convey both technical and sociotechnical limitations. -->
|
108 |
-
|
109 |
-
[More Information Needed]
|
110 |
-
|
111 |
-
### Recommendations
|
112 |
-
|
113 |
-
<!-- This section is meant to convey recommendations with respect to the bias, risk, and technical limitations. -->
|
114 |
-
|
115 |
-
Users should be made aware of the risks, biases and limitations of the dataset. More information needed for further recommendations.
|
116 |
-
|
117 |
-
## Citation [optional]
|
118 |
-
|
119 |
-
<!-- If there is a paper or blog post introducing the dataset, the APA and Bibtex information for that should go in this section. -->
|
120 |
-
|
121 |
-
**BibTeX:**
|
122 |
-
|
123 |
-
[More Information Needed]
|
124 |
-
|
125 |
-
**APA:**
|
126 |
-
|
127 |
-
[More Information Needed]
|
128 |
-
|
129 |
-
## Glossary [optional]
|
130 |
-
|
131 |
-
<!-- If relevant, include terms and calculations in this section that can help readers understand the dataset or dataset card. -->
|
132 |
-
|
133 |
-
[More Information Needed]
|
134 |
-
|
135 |
-
## More Information [optional]
|
136 |
-
|
137 |
-
[More Information Needed]
|
138 |
-
|
139 |
-
## Dataset Card Authors [optional]
|
140 |
-
|
141 |
-
[More Information Needed]
|
142 |
-
|
143 |
-
## Dataset Card Contact
|
144 |
-
|
145 |
-
[More Information Needed]
|
|
|
6 |
- 10M<n<100M
|
7 |
---
|
8 |
|
9 |
+
# Tahoe-100M
|
10 |
|
11 |
+
Tahoe-100M is a giga-scale single-cell perturbation atlas consisting of over 100 million transcriptomic profiles from
|
12 |
+
50 cancer cell lines exposed to 1,100 small-molecule perturbations. Generated using Vevo Therapeutics'
|
13 |
+
Mosaic high-throughput platform, Tahoe-100M enables deep, context-aware exploration of gene function, cellular states, and drug responses at unprecedented scale and resolution.
|
14 |
+
This dataset is designed to power the development of next-generation AI models of cell biology,
|
15 |
+
offering broad applications across systems biology, drug discovery, and precision medicine.
|
16 |
|
17 |
+

|
18 |
+
## Dataset Description
|
19 |
|
20 |
+
### Features
|
21 |
+
The dataset has the following fields:
|
22 |
|
|
|
23 |
|
24 |
+
### Additional metadata
|
25 |
|
26 |
+
### How to use
|
27 |
|
28 |
|
|
|
|
|
|
|
|
|
|
|
29 |
|
|
|
30 |
|
|
|
31 |
|
32 |
+
## Citation
|
33 |
+
Please cite:
|
34 |
+
```
|
35 |
+
@article{zhang2025tahoe,
|
36 |
+
title={Tahoe-100M: A Giga-Scale Single-Cell Perturbation Atlas for Context-Dependent Gene Function and Cellular Modeling},
|
37 |
+
author={Zhang, Jesse and Ubas, Airol A and de Borja, Richard and Svensson, Valentine and Thomas, Nicole and Thakar, Neha and Lai, Ian and Winters, Aidan and Khan, Umair and Jones, Matthew G and others},
|
38 |
+
journal={bioRxiv},
|
39 |
+
pages={2025--02},
|
40 |
+
year={2025},
|
41 |
+
publisher={Cold Spring Harbor Laboratory}
|
42 |
+
}
|
43 |
+
```
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
dataset_size_comparison.png
ADDED
![]() |