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10 record is completely silent on why the court denied Roberson’s petition. The judgment denying Roberson’s petition contains no factual findings, and Roberson’s appellant’s appendix on appeal includes neither a copy of the trial court’s tentative decision, which the trial court adopted as its order denying the petition, or a transcript of the April 2, 2009, court trial on Roberson’s petition. But the administrative record before the trial court did show, and the court was presumably well aware, that the attorneys for Rialto Citizens vigorously challenged the project approvals on behalf of Rialto Citizens at the July 1 city council hearing. The record before the trial court and on this appeal shows the attorneys for Rialto Citizens presented a letter to the city council, which explained in a detailed attachment why the project approvals violated CEQA, the Planning and Zoning Law, the Subdivision Map Act (§ 66410 et seq.), and other laws. The attorneys also submitted an “opposition DVD” for the city council’s consideration. Again, the record on appeal does not indicate that Roberson ever explained to the trial court what written comments or testimony he would have submitted at the July 1 and 15 city council hearings had he known of the planning commission’s recommendation to adopt the project approvals. Nor does the record on appeal indicate that Roberson would have submitted any evidence in opposition to the project approvals other than or in addition to the evidence his attorneys submitted on behalf of Rialto Citizens. Thus, on this record, Roberson did not demonstrate to the trial court that the defect in the notice of the July 1 city council hearing was prejudicial, resulted in substantial 11 injury to Roberson, or that a different result was probable absent the defect in the notice. (§ 65010, subd. (b).) To the contrary, ample evidence supports the trial court’s implied finding—implied in the judgment denying the petition—that the defect in the notice was not prejudicial, did not result in substantial injury to Roberson, and that a different result was not probable if the defect had not occurred. (Ibid.) Even though this court’s July 2012 decision in Rialto Citizens was
freelaw
You agree that ad/agencies won't use it as it does not work for designers, game companies won't use it as it does not work with model pipeline. I repeat that should you guys fail, it makes other tech founders look bad to other investors, and that affects me. You should have done lean process. ------ pdenya Very cool animations and most fit the principals nicely but there's very little info on this page. I found the wikipedia page helpful and relevant - [http://en.wikipedia.org/wiki/12_basic_principles_of_animatio...](http://en.wikipedia.org/wiki/12_basic_principles_of_animation) ------ huxley I'm not generally a big Disney person but the books on animation theory from them that I've bought are quite enjoyable. There is book that the linked-to animation is based on: The Illusion of Life: Disney Animation by Frank Thomas Two other Disney animation resources that I've picked up over the years include: * The 2 volumes of Drawn to Life: 20 Golden Years of Disney Master Classes by Walt Stanchfield * Walt Disney Animation Studios: The Archive Series in 4 volumes: Story (about storyboards not writing), Animation, Design, and Layout & Background I haven't seen the flip books they released recently for each of Disney's "Nine Old Men" but it sounds interesting. ~~~ GuiA I own all of the books mentioned above, as well as the flipbooks. They're really great, but you have to have a certain appreciation of animation beforehand to enjoy the details. It's really just the flipbooks - no accompanying text or anything. It gives you great insight into how talented animators animated certain movements, but you have to know what to look out for. Not Disney, but the Animator's Survival Kit is also heavily recommended. Also recommended: Timing for Animation. I also have been meaning to check out "Elemental Magic" (2 volumes, about animating substances such as water, fire, etc.), and "Setting the Scene". /signed a computer scientist who wishes he can retire and attend CalArts on his startup millions ;) ------ braveheart1723 This is the greatest resource on animation
hackernews
Adolescent partner violence (APV) is an important social and health problem with potentially dire consequences. Youth exposure to IPV is also a problem, and children from families characterized by IPV, compared to children from nonviolent families, are more likely to act violently toward their own dating partners and spouses. However, not all youth exposed to IPV go on to act violently toward others. In fact, although the witnessing of IPV increases risk for perpetration of APV, many youth who
nih_exporter
The comprehensive sexual assault assessment tool. The Comprehensive Sexual Assault Assessment Tool (CSAAT) was developed for collection of data about the victims and offenders in cases of rape and sexual assault. The CSAAT provides a systematic guide for victim assessment, evidence documentation, and initial treatment. Use of the CSAAT facilitates collection of investigative data about the victim and the offender that are critical components of victim interviews and crime investigations, as well as victim forensic data. The CSAAT can be used
pubmed_abstracts
The clearance concept has been used for many years, but the current knowledge remains inadequate for readily designing a targeting system with a clearance step to achieve low blood background. The current investigation focuses on the clearability of biotinylated antibody using avidin as a clearing agent. It is known that avidin does not clear biotinylated antibody completely, but there is no quantitative study as to the exact cause. However, this topic is very important not only for developing a pretargeting technology with clearance, but also for any antibody-based drug for which the background is a concern. In the current investigation, we employed a model pretargeting system to investigate the *in vivo* chemistry between avidin and biotinylated IgG antibody. The aim of this study is not to develop an improved pretargeting protocol but to understand the clearability of biotinylated antibody by avidin. As such, the pretargeting system is used as a research tool for understanding rather than solely for improved pretargeting technology. In this pretargeting system, the antibody CC49 is conjugated concomitantly with a biotin and a morpholino phosphorodiamidate oligomer (MORF). The biotin functions to bind to the clearing agent of avidin, whereas the MORF is for radiolabeling both *in vivo* and *in vitro*. In contrast to most clearance systems, the current design has avoided the binding competition between the clearing agent and the effector. In this investigation, normal mice are used to focus on the determinants of antibody clearance. Tumor accumulation will not be compromised by antibody clearance as previously concluded (Liu et al., [@B9]). Materials and methods {#s2} ===================== The MORF and cMORF (complementary MORF) were custom-synthesized by Gene Tools, LLC (Philomath, OR). Their base sequences and amine derivatization were the same as previously reported (Liu et al., [@B9]). The EZ™ Biotin Quantitation Kit and avidin were from Pierce (Thermo Fisher Scientific, Rockford, IL). The model antiTAG-72 IgG antibody CC49 was prepared by Strategic Biosolutions (Ramona, CA) from its murine hybridoma cell line (a gift from Dr. Jeff Schlom, Center for Cancer Research, NCI, NIH). The biotin-CC49-MORF was synthesized following the reactions illustrated below (Scheme [1](#S1){ref-type="
pubmed_central
Q: Is the D&D Pantheon as invincible as it appears? I've recently taking up the ill-advised task of skimming Deities and Demigods. Numerous times throughout this book, the idea of PCs killing off the gods is entertained. For example, page 31 says that a sufficiently high level Epic party may have an easy time defeating the deities in the book and page 220 has a section devoted to deicide. I can see this being possible for some pantheons. Numerous members of the Asgardian pantheon are quite weak and almost all of them lack Alter Reality, the Olympian pantheon's Nike and Hercules stand out as targets (low Divine Rank and no Alter Reality), and you might have a shot at the weaker members of the Pharaonic pantheon (e.g. Imhotep is DR 1, lacks any instant-kills, and is level 20 Expert). For these cases, I can at least see what the designers were going for. The thing is, I just don't think that this is possible if the DM is using the D&D Pantheon. With the sole exception of the web extension deity Erbin, every single deity in this pantheon has Alter Reality. In my opinion, even under a strict RAW reading of its benefits (i.e. the Notes section), anyone who has this Salient Divine Ability is invincible. I can't even see how another deity can kill them. To support this point, this is how I envision a battle between anyone who has Alter Reality and anyone else: Before the battle, the deity makes use of its immortality, access to any Divination spell it wants (via Alter Reality), and (usually high) intelligence score to access any of a number of exploits for moving first. As soon as the deity becomes aware of a battle or an upcoming battle, the deity moves first and uses Alter Reality to cast Persistent Time Stop. It now has an entire day to prepare for the fight. If that's not enough, it casts it again and again until it is enough. Given that the deity has Alter Reality, it can do pretty much anything to prepare for the battle. My favorite is dropping an arbitrarily high mass on top of the opponent, but I'm sure that the ability to create temporary magic objects is even more useful (scrolls, any one?). The only limitations are those
stackexchange
The present invention relates to a liquid biocidal composition containing (a) formaldehyde adduct compounds and (b) an isothiazolone, which is intended to provide synergistic biocidal. activity against bacteria and fungi. More particularly, the present invention relates to the use of a biocide composition which includes formaldehyde adduct compounds and 1,2- benzisothiazolin-3-one. 2. Description of the Prior Art Synergistic biological activity exists when the combination of lesser quantities of two biocidal agents results in an equal or greater inhibitory effect than is achieved by the use of either agent acting alone. The synergistic interaction of two or more antimicrobial agents produces an effect that is more than additive in its resultant biological activity. Formaldehyde adduct compounds are known biocides; their proposed biological target is the cell wall of susceptible microorganisms (S. P. Denyer, 1990. Mechanisms of action of biocides. International Biodeterioration, 26:89). Examples of such adduct compounds includeN-methyl-2-hydroxymethyleneoxypropyl-2xe2x80x2-hydroxypropylamineanditsformaldehyde oligomers (manufactured by Creanova Inc., Somerset, N. J. under the trademark NUOSEPT(copyright) 145, hereinafter xe2x80x9cNMPFAxe2x80x9d); oxazolidines such as (4,4-dimethyloxazolidine, manufactured by Creanova Inc. under the trademark NUOSEPT(copyright) 101, hereinafter xe2x80x9cDMOxe2x80x9d), mixtures of bicyclic oxazolidines (such as (5-hydroxymethoxymethyl-1-aza-3,7-dioxabicyclo(3.3.0) octane,5-hydroxymethyl-1-aza-3,7-dioxabicyclo(3.3.0)octane,5-hydroxypoly[methyleneoxy-methyl-1-aza-3,7-dioxabicyclo (3.3.0) octane; manufactured by Creanova Inc. under the trademark NUOSEPT(copyright) 95, hereinafter xe2x80x9cMBOxe2x80x9d; and 2-[(hydroxymethyl) amino]ethanol, (manufactured by Creanova Inc. under the trade mark NUOSEPT(copyright) 91,
uspto_backgrounds
For similar reasons, Brilliant Blue FCF is also being utilized in hemostatic medical devices, most notably the HEMOPATCH—designed to be placed on bleeding tissues and coagulate the blood. A low concentration of Brilliant Blue FCF is placed on the backside of the HEMOPATCH at 1 cm increments, allowing surgeons to cut precisely and indicate the side of the HEMOPATCH that is an active hemostatic agent for correct placement. Brilliant Blue FCF is an approved food colorant and pharmacologically inactive substance for drug formulations in the EU and the United States. It is also legal in other countries. It has the capacity for inducing allergic reactions in individuals with pre-existing moderate asthma. In 2003, the U.S. FDA issued a public health advisory to warn health care providers of the potential toxicity of this synthetic dye in enteral feeding solutions. The following legal limits apply in the EU (E 131) and other countries: 150–300 mg/kg depending on the type of food. Safety limit for foods and drugs: 0.1 mg/day per kg body weight. The ADI for Brilliant Blue FCF is 6 mg/kg. Biomedical research Brilliant Blue FCF and similar dyes such as Brilliant Blue G are inhibitors to purinergic receptors—receptors that are responsible for inflammatory responses and other cell process. Scientists who were conducting in-vivo studies of compounds to lessen the severity of inflammation following experimental spinal cord injury had previously tested a compound called OxATP to block a key ATP receptor in spinal neurons. However, OxATP has toxic side effects and must be injected directly into the spinal cord; in searching for alternatives they noted that Brilliant Blue FCF has a similar structure. This led them to test a related dye, Brilliant Blue G (also known as Coomassie Brilliant Blue) in rats, which improved recovery from spinal cord injury while temporarily turning them blue. When human washed platelets are evaluated using turbidimetry it was found that Brilliant Blue FCF affects platelet aggregation by blocking the Panx1 channels. These inhibitory effects on collagen-induced shape change and maximal aggregation were shown by high (1 mM) concentrations of the dye but not by lower concentrations (100 μM). The 1 mM effective concentration is 1.59 times greater than the approximately 0.63 mM maximal allowable Brilli
wikipedia_en
The first direct radio detection with low frequency Giant Metrewave Radio Telescope (GRMT) observations and discussion of the “green peas” properties comprising properties of a new class of sub-mJy sources were reported by @C12. It was shown that this detection may imply large magnetic fields ( $ \gtrsim 30 \, \mu $G) in “green peas” under reasonable assumption about cosmic ray diffusion and total energy consideration. @C12 concluded that seed fields were amplified significantly (up to $\mu$G) because of turbulence as protogalactic and similar structures formed. Detailed examination of a large sample of 803 star-forming luminous compact galaxies (LCGs) in the redshift range $z$ = 0.02 - 0.63 was carried out by @I11. These galaxies were selected from the SDSS Data Release 7 (DR7) [@A09] and comprise a complete spectroscopic SDSS sample of strongly star-forming LCGs with reliably derived chemical abundances. Their global properties are similar to those of the star-forming “green pea” galaxies. However, in contrast to “green pea” galaxies, the LCGs are selected on the base of the both their spectroscopic and photometric properties. Applied selection results in a $\sim$ 10 times larger sample, with galaxies spanning a redshift range about $\sim$ 2 times larger as compared to “green pea” sample [@C09]. For LCGs, the oxygen abundances 12 + log O/H are found to be in the range 7.6 - 8.4 with the median value of $\sim$ 8.11 confirming the results by @A10 for a subset of the “green pea” sample of @C09. The ranges of oxygen abundances and heavy element abundance ratios in LCGs are similar to those of nearby low-metallicity BCDs. In the \[O [iii]{}\]$\lambda$5007/H$\beta$ vs. \[N [ii]{}\]$\lambda$6583/H$\alpha$ diagnostic diagram [@K03] the LCGs are shown to occupy the region of high-excitation star-forming galaxies. The SFRs, derived from the H$\alpha$ line emission in the LCGs are revealed to vary in the large range of 0.7 - 60 $M_\odot$ yr$^{-1}$, with a median value of $\sim$ 4 $M_\odot$ yr$^{-1}$ which is about 3 times lower as compared to
arxiv
*> *> If the elements of x are all zero and alpha is real, then tau = 0 *> and H is taken to be the unit matrix. *> *> Otherwise 1 <= real(tau) <= 2 and abs(tau-1) <= 1 . *> \endverbatim * * Arguments: * ========== * *> \param[in] N *> \verbatim *> N is INTEGER *> The order of the elementary reflector. *> \endverbatim *> *> \param[in,out] ALPHA *> \verbatim *> ALPHA is COMPLEX *> On entry, the value alpha. *> On exit, it is overwritten with the value beta. *> \endverbatim *> *> \param[in,out] X *> \verbatim *> X is COMPLEX array, dimension *> (1+(N-2)*abs(INCX)) *> On entry, the vector x. *> On exit, it is overwritten with the vector v. *> \endverbatim *> *> \param[in] INCX *> \verbatim *> INCX is INTEGER *> The increment between elements of X. INCX > 0. *> \endverbatim *> *> \param[out] TAU *> \verbatim *> TAU is COMPLEX *> The value tau. *> \endverbatim * * Authors: * ======== * *> \author Univ. of Tennessee *> \author Univ. of California Berkeley *> \author Univ. of Colorado Denver *> \author NAG Ltd. * *> \date November 2011 * *> \ingroup complexOTHERauxiliary * * ===================================================================== SUBROUTINE CLARFG( N, ALPHA, X, INCX, TAU ) * * -- LAPACK auxiliary routine (version 3.4.0) -- * -- LAPACK is a software package provided by Univ. of Tennessee, -- * -- Univ. of California Berkeley, Univ. of Colorado Denver and NAG Ltd..-- * November 2011 * * .. Scalar Arguments .. INTEGER INCX, N
github
2. Hot Dog One hot dog for a 20 pound puppy is the caloric equivalent of three hamburgers for a person. That single hot dog may not look like much but it has around 175 calories, which is a third of what a 20 pound dog should be consuming. “I think people get gratification out of their pet eating and being happy about it, but they don’t think about the long-term consequences,” says Dr. James Darden, DVM, chief of staff at Banfield Pet Hospital in East Houston, Texas. 3. Cheese One ounce of cheese for a 20 pound dog is the caloric equivalent of 1 ½ chocolate bars for a person. Cheese is loaded with fat — a single 1 oz. slice of American cheese packs 105 calories and 5.5 grams of saturated fat, while Cheddar is even worse: 114 calories and 6 grams of fat. That ounce of cheese constitutes about a third of a small dog’s daily required calories, says Dr. Darden. “And for a cat it’s worse — it’s about half his daily caloric intake, so two slices of cheese for a cat is all it needs in a day.” 4. Potato Chip One potato chip for a 10 pound cat is the caloric equivalent of half a hamburger for a person. You may think that a thin potato chip is lighter than air, but don’t forget that it’s been fried in saturated fat and coated in sodium. For your small cat, you’re almost providing lunch with a potato chip. A superior option, says Dr. Darden, is a small handful of kibble. He suggests you subtract whatever you feed your cat as a snack from her evening meal so she doesn’t overeat. 5. Cup of Milk One cup of milk for a 10 pound cat is the caloric equivalent of five chocolate bars for a person. Besides the fact that whole milk provides 122 calories per cup — and even skim clocks in at 86 calories — neither dogs nor cats should drink it because it can upset their stomach, says Dr. Darden. A good alternative is fruits or vegetables, especially frozen, such as green beans, peas, and apples. (Ed. Note: Consult your vet before providing any "human food," as some fruits and vegetables are dangerous for pets.) 6. Peanut Butter A single ounce of peanut butter (about a tablespoon) is close to
pile-cc
b Let p = -6 - -5.9. Which is the nearest to p? (a) 3/8 (b) -1 (c) -0.1 c Let g(r) = -r - 2. Let z be g(0). Let x = 33 - 35. What is the closest to x in -0.1, -5, z? z Let q = 17 + -6. Let a = q - 9. What is the nearest to -2/7 in a, 2/13, -3? 2/13 Let w = 101.7 - 96. Let r = 1.6 - w. Let f = r + 4. Which is the nearest to -2/5? (a) 5 (b) f (c) 1 b Let h = 1/9 + -4/9. What is the nearest to 2/7 in h, -2/3, -0.2? -0.2 Let m = 1.6 + -2. Which is the closest to 0.1? (a) m (b) -4 (c) -0.5 a Let v = -1 - -0.6. Let d = -0.3 + 0. Let b = d - v. What is the closest to 2/3 in -4, b, -1? b Let u = 10 + -12. Let r = -1 - -0.8. What is the nearest to 0 in u, -5, r? r Let t = 11 - 10. Which is the closest to t? (a) 1 (b) 2 (c) 1/5 a Let j(y) = y**3 - y**2 - 3*y + 2. Let i be j(3). Suppose -2*b - 3*z - i = 0, 4*b + 0*z - 5 = 3*z. Let u = -2.8 + 3. What is the closest to b in -3/8, u, -5? -3/8 Let o = -0.94 + 1.04. Which is the closest to 2/3? (a) 0.4 (b) o (c) 0 a Let b = 0
dm_mathematics
Dmitri Villevald <[email protected]> on 02/15/2001 04:00:51 PM To: "'[email protected]'" <[email protected]> cc: Subject: Dear Ms. Gandy: Thank you for taking time out of your busy schedule to visit the Owen
enron_emails
1 MEMORANDUM** 2 Raj Kumar Sandhi appeals from the Board of Immigration Appeals' ("BIA") denial of his application for asylum and withholding of deportation. He disputes the BIA's determination that his testimony was not credible, that his interrogation by the police was a legitimate prosecutorial act and that, in any event, he was ineligible for asylum because he failed to show a nationwide threat of persecution. Because Sandhi cannot overcome the adverse credibility findings by the BIA, we affirm. I. FACTS AND PROCEDURAL HISTORY 3 Raj Kumar Sandhi, a Sikh native and citizen of the Punjab, India, entered this country in August, 1991. On August 28, 1991, the Immigration and Naturalization Service ("INS") issued him with an Order to Show Cause, charging him with being deportable pursuant to 8 U.S.C. Sec. 1251a(1)(B) for entering the United States without inspection. Sandhi admitted deportability, but applied for asylum and withholding of deportation. At his hearing, Sandhi told the following story of political persecution. 4 Sandhi testified that his troubles began in September, 1990, when Sikh militants, who advocate the use of violence to create an independent Sikh state (Khalistan), came to his home to recruit him. He said he refused to join, and told them that, while he supported the creation of Khalistan, he did not believe the Sikh religion permitted the use of violent methods to achieve these ends. He said the militants warned him they would kill him if he should become involved in the government. 5 Sandhi said the militants repeated their demands a month later, again to no avail. He said that the militants threatened to kill him, but gave him another chance. According to Sandhi, his third and final encounter with the militants took place in February of 1991, when he again refused to join them, but again was given another chance to reconsider. 6 Sandhi told the IJ he was afraid the militants would carry out their threats. He testified that he knew of others who had been killed by Sikh militants after refusing to join them. 7 Sandhi also told the IJ about his troubles with the police, who came to his home in March, 1991, and told him they suspected him of involvement with the Sikh militants. Sandhi testified that he was taken
freelaw
It could just be me as a programmer not trusting the projection, or finding little value in it, because I know it's based on limited information. For example, if I know I'm going to buy $5k worth of ads tomorrow, and I know inDinero has no way of knowing this yet (because it's just an idea in my head), then the projection is wrong. What do you think? ~~~ arram I'd agree with this. I was having problems with Quickbooks last week, so I tried some of the major online accounting services, including Xero, Outright, and Quickbooks Online. Of these, InDinero was my favorite. Though I still think they're going to have a hard time overcoming the chief advantage of Quickbooks - that my accountant knows it. ~~~ alttab Usability will effect retention and adoption rates - but overall doing a critical business function better or easier than their competitor - Quickbooks - will be the winning factor here. This means financial statements, tax planning and integration, and proactive alerting and real-time status. Branching out to integration with Freshbooks for invoicing and billing (as I believe they have done) along with multi-user, tiered accounting and HR integration (they do most of the accounting for small businesses), and resource planning. ------ dusing When I connected my freshbooks account I got this email. Pretty clever, they probably get good feedback from this by offering a seemingly direct connection to devs. Hi there, Hope the FreshBooks integration is working well for you! Wondering if you have any additional ideas or suggestions for us? Thanks :) \- Chris Zhang (the engineer who built the integration with FreshBooks) ~~~ cjzhang :D That's meeeee~ But to be fair, it's not a "seemingly" direct connection, it's an actual direct connection. In a company with no sales or marketing or support staff, who do you think answers support emails? ------ kineticac awesome coverage everywhere for inDinero! Looks to really be catching on as something people need and want to use. ------ callmeed I started a new LLC for some side projects and setup my Chase bank account
hackernews
Evidence suggests that for the most part gp4l neutralizing epitopes are cryptic, and this is most likely related to the functional role of the transmembrane protein (TM) in mediating virus entry. It has been shown that gpl2O-CD4 binding causes the HIV envelope to undergo a series of conformational changes, which may be driven by the formation of a series of structural intermediates within gp41, leading ultimately to virus entry. Previous work in the applicant's laboratory has identified two regions within the ect
nih_exporter
Each section of the Alderson Rando phantom contains a tissue-equivalent plastic coating layer approximately 2 mm thick, applied to both faces. This compensates for material removed in the sawing process. Conventional use of thermoluminescent dosimeters positions them totally or partially within the coating layer. Analysis shows that, in the lung region, dosimeters placed in this layer received a dose averaging 39% lower than those placed at midsection. Where bony structures interfere, some dosimeters in the coating layer received
pubmed_abstracts
As some children with NF1 exhibit cognitive deficits and neurodevelopmental delays ([@bib12], [@bib13], [@bib14], [@bib20]), we sought to determine the effects of distinct *NF1* germline mutations on human CNS neuronal function and differentiation. Based on the observation that *Nf1-*mutant (*Nf1+/−*) mice exhibit increased GABAergic tone that contributes to the observed deficits in learning and spatial memory ([@bib5], [@bib6]), we assayed GABA levels in NPC-derived GABAergic neurons ([Figures 3](#fig3){ref-type="fig"}B and [S3](#mmc1){ref-type="supplementary-material"}E). In all *NF1*-mutant neurons (2D cultures), GABA levels were increased (6.5- to 7.8-fold) relative to isogenic control neurons, revealing a shared abnormality in all *NF1*-mutant GABAergic neurons. In contrast, *NF1-*mutant NPCs in 2D cultures displayed striking differences in dopamine (DA) ([Figure 3](#fig3){ref-type="fig"}C) levels. DA levels were reduced by \>70% in the c.1149C \> A, c.2041C \> T, and c.6619C \> T *NF1* mutants, but by \<40% in the c.1185+1G \> A, c.3431-32_dupGT, c.5425C \> T, and c.6513T \> A *NF1* mutants relative to the control line. These differential effects mirror findings using patient-derived NPCs ([Figures S3](#mmc1){ref-type="supplementary-material"}E and S3F; [Table S1](#mmc1){ref-type="supplementary-material"}) ([@bib2]), as well as mice engineered with NF1 patient-specific *Nf1* germline mutations ([Figure 3](#fig3){ref-type="fig"}D) ([@bib27]). Taken together, these findings demonstrate the existence of differential effects of *NF1* germline mutations on neuronal differentiation *in vitro*. Differential Effects of *NF1* Mutations on Cerebral Organoid NPC Proliferation, Apoptosis and Differentiation {#sec2.4} ------------------------------------------------------------------------------------------------------------- To further explore the differential effects of *NF1* mutations in the developing human brain, we used
pubmed_central
adding comments using php and html I was wondering if there were any kind people out there who would be able to help me with my php conundrum! Im very very new to php and I can't quite understand how to add a comment section that is functional. I have made a database table (named 'comments') to store all of the comments that users will submit. I am not sure of these things: 1. how to connect the comment section (on php page - home.php) to my database table (comments) 2. how to make the comments that people post be posted onto the the same page - home.php I have done something wrong as now when I type in the URL this error comes up Parse error: syntax error, unexpected '{', expecting '(' in .../home.php on line 34 Anyway I hope someone can help me! Thanks <?php session_start(); if (!isset($_SESSION['logged'])){ $_SESSION = array(); session_destroy(); header('location: home_start.php'); //your login form require_once("functions.php"); include_once("home_start.php"); require_once("db_connect.php"); } //EXISTING DATABASE CONNECTION CODE //if (!$db_server){ //die("Unable to connect to MySQL: " . mysqli_connect_error($db_server)); }else{ $ db_status = "not connected"; //NEW SUBMISSION HANDLING CODE HERE //if(trim($_POST['submit']) == "Submit"){ //}//EXISTING CODE (to create the options list) HERE... //} require_once('recaptcha/recaptchalib.php'); $privatekey = " 6Lem4-gSAAAAADsaa9KXlzSAhLs8Ztp83Lt-x1kn"; $resp = recaptcha_check_answer ($privatekey, $_SERVER["REMOTE_ADDR"], $_POST["recaptcha_challenge_field"], $_POST["recaptcha_response_field"]); $message = ""; if (!$resp->is_valid) { $message = "The reCAPTCHA wasn't entered correctly. Go back and try it again
stackexchange
The Universal Mobile Telecommunications System (UMTS) is a third-generation (3G) mobile phone technology standardized first by the European Telecommunications Standards Institute (ETSI) and now by the 3rd Generation Partnership Project (3GPP). UMTS carries both circuit switched (CS) and packet switched (PS) traffic using Wideband Code Division Multiple Access (W-CDMA) as its air interface. The description of the network components and protocols used in UMTS are well known to those of ordinary skill in the art and are available to the public from 3GPP, ETSI, and other sources. The UMTS network architecture consists of three domains: Core Network (CN), UMTS Terrestrial Radio Access Network (UTRAN), and User Equipment (UE). The Core Network provides switching and routing for user traffic and provides network management functions. The Core Network architecture is based on the GSM network with GPRS. The UTRAN provides the air interface access to subscribers' UE. Base stations in the UTRAN are referred as Node-Bs, and the control equipment for the Node-Bs is called a Radio Network Controller (RNC). The UMTS User Equipment communicates via the WCDMA air interface to the Node-Bs. The UE may be attached to either the PS domain or CS domain or both. The UE is capable of simultaneously using PS services and CS services. The Asynchronous Transfer Mode (ATM) is used for data transmission in UMTS. The ATM layer multiplexes and demultiplexes and routes ATM cells, and ensures their sequence from end to end. The ATM Adaptation Layers (AAL) are responsible for the creation and reception of payloads through the lower layers of ATM on behalf of different applications. ATM Adaptation Layer type 2 (AAL2) handles circuit-switched connections and packet connection protocol AAL5 is designed for data delivery. One disadvantage of the prior art is the difficulty in evaluating service levels for individual subscribers. Because multiple UEs are communicating with Node Bs and RNCs at the same time, thousands of data and control messages per second can be passed between a Node B and an RNC and between RNCs. These messages follow several different protocol formats depending upon the purpose of the message. As a result, the messages passing on interfaces in the UTRAN do not provide sufficient information to determine which messages are related to the same subscriber. A second disadvantage of the prior art is the lack of a
uspto_backgrounds
Richard W. Hughes is an American gemologist and award winning author, known as an authority on corundum, rubies and sapphires. Career A.G. graduate of Bangkok's AIGS (1980), and a Fellow of the Gemmological Association of Great Britain (F.G.A.) (1982). He was the director of the Asian Institute of Gemological Sciences in Bangkok, Thailand during the 1980s, and also served at the American Gem Trade Association’s gemological laboratories in California and New York from 2005 to 2008. In 1997 he authored Ruby & Sapphire, which is considered by many in the gem and jewelry industry to be the most authoritative treatise on the subject. Hughes has authored or co-authored a number of books on gems as well as numerous articles on gemology over the past 34 years. In recognition of his contributions Hughes has received the American Gem Society's Richard T. Liddicoat Journalism Award in both 2004 and 2005. In 2010 Hughes received The Antonio Bonanno Award for Excellence in Gemology. Hughes has worked both in lab gemology and also in the wholesale, retail and mining sides of the gem business. He currently resides in Thailand with his Thai wife and daughter, where he is engaged in continued gemological research. In 2012 together with the family, he has established a Gemological laboratory in Bangkok called Lotus Gemology. In 2010, Richard was awarded the prestigious Antonio C. Bonanno Award for Excellence in Gemology by the Accredited Gemologists Association. This award recognizes Richard’s efforts in successfully advancing the profile of many gems and the countries that produce them through his travelogues, as well as more scientific writings and the generous sharing of this information through trade journals and his website. The award underscores the responsibility of the international gemological community to encourage and reward ongoing research, education and dissemination of information. Books Terra Spinel: Terra Firma, Yavorskyy, V. and Hughes, R.W. (2010). Yavorskyy Co., 202 pp., Ruby & Sapphire, Hughes, R.W. (1997) Boulder, CO, RWH Publishing, 512pp. Corundum, Hughes, R.W. (1990). Butterworth’s Gem Books, Northants, UK, Butterworth-Heinemann, 314 pp., The Book of Ruby &
wikipedia_en
Emission Line Measurements {#emission-lines} -------------------------- The emission lines of interest were fitted with <span style="font-variant:small-caps;">sherpa</span> [@SHERPA], a general-purpose fitting environment designed for CIAO, the Chandra (X-Ray Observatory) Interactive Analysis of Observations software package [@CIAO]. <span style="font-variant:small-caps;">sherpa</span> can handle multi-component models (Fig. \[sherpa\]) such as emission lines with broad components (e.g., Seyfert 1 galaxies) or doubled-peaked line profiles resulting from galaxy rotation. One of the most important advantages of <span style="font-variant:small-caps;">sherpa</span> is its capability of fitting spectra accounting for the flux density uncertainties. We fitted the intensity, full width at half-maximum (FWHM), and central wavelength of each emission line using Gaussian profiles and a constant for the local continuum. The latter is a good approximation given that we are fitting the starlight-subtracted spectra. Uncertainties for the parameters were calculated at the 1$\sigma$ confidence intervals. This was done by varying a parameter’s value in a grid of values while at the same time the values of the other model parameters were allowed to float to new best-fit values. We measured the intensities of the forbidden lines \[O<span style="font-variant:small-caps;">iii</span>\] $\lambda$5007, \[N<span style="font-variant:small-caps;">ii</span>\] $\lambda$6583, \[S<span style="font-variant:small-caps;">ii</span>\] $\lambda\lambda$6716, 6731, \[O<span style="font-variant:small-caps;">i</span>\] $\lambda$6300, and the Balmer H$\beta$ and H$\alpha$ lines. For five galaxies (NGC 3758, UGC 8058, IRAS 13218+0552, MK 268, and UGC 9412) having spectra with extremely broad lines (Fig. \[Type1AGN\]) no emission line fitting was performed, since from the profile of the lines they could be clearly classified as AGN. Therefore, they were assigned a Sy-1 classification (see Section \[Final\_Class\]). The emission-line intensity
arxiv
#include <cstddef> #include <boost/system/error_code.hpp> #include <boost/asio/detail/socket_types.hpp> #include <boost/asio/detail/push_options.hpp> namespace boost { namespace asio { namespace detail { namespace descriptor_ops { // Descriptor state bits. enum { // The user wants a non-blocking descriptor. user_set_non_blocking = 1, // The descriptor has been set non-blocking. internal_non_blocking = 2, // Helper "state" used to determine whether the descriptor is non-blocking. non_blocking = user_set_non_blocking | internal_non_blocking, // The descriptor may have been dup()-ed. possible_dup = 4 }; typedef unsigned char state_type; template <typename ReturnType> inline ReturnType error_wrapper(ReturnType return_value, boost::system::error_code& ec) { ec = boost::system::error_code(errno, boost::asio::error::get_system_category()); return return_value; } BOOST_ASIO_DECL int open(const char* path, int flags, boost::system::error_code& ec); BOOST_ASIO_DECL int close(int d, state_type& state, boost::system::error_code& ec); BOOST_ASIO_DECL bool set_user_non_blocking(int d, state_type& state, bool value, boost::system::error_code& ec); BOOST_ASIO_DECL bool set_internal_non_blocking(int d, state_type& state, bool value, boost::system::error_code& ec); typedef iovec buf; BOOST_ASIO_DECL std::size_t sync_read(int d, state_type state, buf* bufs, std::size_t count, bool all_empty, boost::system::error_code& ec); BOOST_ASIO_DECL bool non_blocking_read(int d, buf* bufs, std::size_t count,
github
Posted by Xavier Hamon on 25 November 2013 Last coffee season saw a massive outbreak of a devastating fungus that seemed to take everyone by surprise. The coffee leaf rust epidemic stretched from Mexico to Peru, infecting more than half of Central America’s coffee farms and costing $1 billion in crop losses. The worst affected families stripped back their entire farms, prized coffee trees reduced to kindling, and faced a stark choice – is it worth replanting when coffee prices are so low? Oversupply coming in Brazil has caused the New York coffee price to fall through the floor, and is now likely to be below cost of production for many farmers. In this context, it is hardly surprising that many farmers and governments are investing less in coffee, which hints at a key contributing factor to the outbreak in the first place. Ageing coffee plants and chronic under investment in good farm management has left many farms in a vulnerable state. As Esperanza Dionisio, General Manager of Pangoa coffee cooperative in Peru and Twin Board Member, put it to me “it’s like tuberculosis, if you don’t eat properly, you are weakened to the disease. The leaf works in the same way; if the plant is not healthy and didn’t receive organic fertilisers, it is more susceptible to rust.” The increase in extreme weather events in the region has also been associated with weakened coffee trees. You could therefore view this outbreak as just another symptom of climate change. Without investment, future such events are likely to be less and less surprising as changes to our climate look set to cause an upsurge in agricultural pests and diseases. Peter Baker of CABI speaking at Twin and the Fairtrade Foundation’s recent joint coffee rust industry event summed it up nicely: “think of it as an earthquake that reveals we were sitting all the time on a fault line.” So, as well as responding to this crisis, it is vital that we treat the cause and not just the symptom. Twin’s approach to sustainable agriculture aims at strengthening overall resilience to climate change. One example is our Big Lottery Fund project in Nicaragua, which supports five Cafénica coffee cooperatives using climate field schools. Farmers can experiment and share their ideas on farm practices such as plant nutrition, soil erosion and shade management on special plots, as well as learn from experts and benefit from technology transfer. They can apply these learnings to their own farms thanks to a dedicated Smallholder Coffee Adaptation fund,
pile-cc
-d**2*(d - 2)/5 Let u(v) = v**2. Let l(w) = 2*w**2 - 17*w**2 + 6*w + 12 + 6*w. Let s(i) = -l(i) - 18*u(i). Determine h, given that s(h) = 0. -2 Let j(z) be the second derivative of z**4/12 - 17*z**3/3 - 3*z + 44. Factor j(c). c*(c - 34) Let d be (-2)/(-5) + (-17292)/(-770) + -22. Determine a so that 0 - d*a**2 + 0*a + 2/7*a**3 = 0. 0, 3 Factor 1/2*p**5 + 0*p + 0 + p**4 - p**2 - 1/2*p**3. p**2*(p - 1)*(p + 1)*(p + 2)/2 Let x = 1 + 1. Factor -447*r**x + 449*r**2 - 3*r + 3*r - 2*r**3. -2*r**2*(r - 1) Find o, given that -2/7*o**4 + 0 + 8/7*o + 12/7*o**3 - 18/7*o**2 = 0. 0, 1, 4 Let k(q) be the first derivative of q**9/15120 + q**8/4200 - q**6/900 - q**5/600 - 4*q**3/3 + 11. Let u(a) be the third derivative of k(a). Factor u(t). t*(t - 1)*(t + 1)**3/5 Let k(m) be the third derivative of m**7/210 + m**6/16 + 7*m**5/60 - 17*m**4/16 + 5*m**3/3 + 157*m**2. Suppose k(q) = 0. Calculate q. -5, -4, 1/2, 1 Factor -2 + 5097*c + 2 - 4835*c + 2*c**2. 2*c*(c + 131) Let k(
dm_mathematics
-----Original Message----- From: Sager, Elizabeth Sent: Wednesday, October 03, 2001 2:45 PM To: '[email protected]' Cc: Mellencamp, Lisa; Wright, Alice Subject: Amendment to Master Netting Agreement At the request of Robert Eickenroht, attached is a draft of the Second Amendment to the Master Netting Agreement between New Power and the
enron_emails
No. 10-3548 _______________ NATIONAL LABOR RELATIONS BOARD, Petitioner v. REGENCY GRANDE NURSING AND REHABILITATION CENTER, Respondent ______________ On Appeal from the National Labor Relations Board (NLRB-1 : 22-CA-28331 NLRB-1 : 22-CA-28384 NLRB-1 : 22-RC-12889 NLRB-1 : 22-RC-12895) ______________ Submitted Pursuant to Third Circuit LAR 34.1(a) June 21, 2011 BEFORE: BARRY, AMBRO and COWEN , Circuit Judges (Filed: August 9, 2011 ) _______________ OPINION _______________ COWEN, Circuit Judge. This case is before the Court on an application of the National Labor Relations Board (the “Board”) to enforce an order entered on August 23, 2010 against Regency Grande Nursing and Rehabilitation Center (“Regency Grande”). For the reasons that follow, we will enforce the order. I. In 2005, the Board found that Regency Grande had engaged in unfair labor practices at its Dover, New Jersey facility during organizing efforts by Local 300S, a union affiliated with the United Food and Commercial Workers Union, and Local 1199 of the Service Employees International Union (“SEIU”). Specifically, the Board found that Regency Grande had violated Sections 8(a)(1), (2), and (3) of the National Labor Relations Act (the “Act”) by recognizing Local 300S as the exclusive collective- bargaining representative of employees and entering into a collective-bargaining agreement with Local 300S at a time when that union did not represent a majority of those employees. Regency Grande Nursing & Rehab. Ctr., 347 NLRB 1143 (2006). Upon review, this Court found that substantial evidence supported the Board’s findings and enforced the Board’s order. N.L.R.B. v. Regency Grand Nursing & Rehab. Ctr., 265 F. App’x 74 (
freelaw
If Earth Was 50% Larger, We Might Be Stuck Here - sjcsjc https://www.realclearscience.com/blog/2017/07/06/if_earth_was_50_larger_we_might_be_stuck_here.html ====== rthomas6 How close are we to a feasible space elevator? Once we have something that can withstand the forces involved, we can just ride up to space for a fraction of the energy and cost, and start our propulsion from orbit instead of the surface. ~~~ willcipriano As I understand it, very far. The materials science isn't there, we have yet to conceive of a material that would be able to carry it's own weight let alone move a useful load. ~~~ avmich No, the problem isn't in the material, that's relatively easy part, we already have good prototypes in carbon nanotubes. ~~~ willcipriano My source: > "No current material exists with sufficiently high tensile strength and > sufficiently low density out of which we could construct the cable," he told > me. "There's nothing in sight that's strong enough to do it — not even > carbon nanotubes." "The best that theorists can do right now is come up with a material that's about two-thirds the strength needed to make a practical elevator," Henson told me. "And that's a very, very short tiny tube."[0] [0][https://io9.gizmodo.com/why-well-probably-never-build-a- spac...](https://io9.gizmodo.com/why-well-probably-never-build-a-space- elevator-5984371) ------ scaredginger The title should have mentioned the measure was diameter, rather than mass or volume. They give wildly different outcomes. ------ gaukes Anyone think this is an additional factor in the Fermi paradox? i.e planets that are too small can’t support a strong atmosphere and life. Planets that are too big make space travel too uneconomical. ~~~ c22 I've often considered an alien planet with an atmosphere so thick that one couldn't see the night
hackernews
It has been estimated that more than one third of patients with neurological disorders with problems affecting the neuromuscular system. Striking progress has been made in understanding many of these diseases, and in the effective application of the new knowledge to treatment. This progress has been made possible by the intimate interaction of basic and clinical scientific approaches. At the same time, the analysis of human neuromuscular diseases has contributed to the understanding of the basic biology of nerves, muscles, and nerve-muscle interactions. The goal of
nih_exporter
Features of stabbing, cough, exertional and sexual headaches in a Turkish population of headache patients. The aim of this study was to determine the features and prevalence of primary stabbing headache, primary exertional headache, primary headache associated with sexual activity, and primary cough headache in a Turkish population of headache patients. The data for this study were obtained from 245 patients with headache. Of these patients, 55 fulfilled the International Classification of Headache Disorders (second edition) diagnostic criteria for 'other primary headaches
pubmed_abstracts
Statistical analysis -------------------- Nonparametric tests were used throughout the study. The Mann-Whitney U test was used for evaluating the difference between different groups, and Spearman\'s rank correlation coefficient for evaluating correlations. For all tests *P*\< 0.05 was considered significant. Graphpad Prism 4.0 (Graphpad software, La Jolla, CA, USA) was used for statistics. Results ======= Patients -------- Two hundred and thirty-two patients were included. Seventy patients were diagnosed with severe sepsis, 99 patients with sepsis, 43 patients with infection without SIRS, and 20 patients with SIRS without infection. Detailed patient demographic data and diagnoses have been presented elsewhere \[[@B16]\]. Pneumonia and urinary tract infections were common and also overrepresented in the severe sepsis and the sepsis groups. Infected patients without SIRS suffered mostly from upper respiratory infections. The 20 patients with non-infectious SIRS suffered from various diseases such as vasculitis, cardiac failure, gastrointestinal bleeding, pulmonary embolism and pancreatitis. The over-all mortality rate was 3.4%. In the severe sepsis group, the mortality rate was 10%, and out of the 26 patients with septic shock, 19% died. Plasma levels of Gas6 and sAxl ------------------------------ The plasma concentrations of Gas6 and sAxl were determined in the acutely ill patients who were found to suffer from severe sepsis, sepsis, infections without SIRS, or SIRS without infection (Figure [1](#F1){ref-type="fig"}). When compared to the controls, all patient groups had significantly increased plasma concentrations of Gas6, the median Gas6 concentration being 0.58, 0.50, 0.48 and 0.52 nM for the patient groups and 0.25 nM for the controls. The patients with severe sepsis had significantly increased Gas6 concentrations when compared to the sepsis group (Figure [1a](#F1){ref-type="fig"}). The median plasma sAxl concentrations were 1.19, 1.00, 1.14, 1.29 and 0.99 nM, respectively. There were also statistical differences in sAxl between the controls and the patient groups, but they were not close to the significance levels observed for Gas6. There were several individuals with very high sAxl concentrations in the patient groups, but the differences between the groups were less pronounced than what was found for Gas6 (Figure [1b](#F1){ref-type="fig
pubmed_central
return false; }, { height: 280, reloadAfterSubmit: true }, // edit options {width: 600, reloadAfterSubmit: true, top: 100, left: 300, addCaption: 'Add Blog Post' }, // add options {reloadAfterSubmit: true }, // del options {} // search options ); $('.wysiwyg').livequery(function () { $(this).wysiwyg(); }); </script> UPDATE: The problematic line of code is $(dialogId).load('http://localhost:24533/Admin/BlogPostEdit?id=' + rowid, function () { After you do jQuery.load() the jqGrid's programmatic reload binding call trigger("reloadGrid") doesn't work anymore. The only way to reload the data that works after you do jQuery.load() is the reload button in the toolbar. I still don't know how to fix it. UPDATE2 (solution): The problem was in HTML returned from jQuery.ajax() it was a full HTML page with HTML head and body tags. After server side started to return only the form jqGrid reload started to work. A: I think the problem exist because you use $(form).submit(). What you probably want to do is to send data from the form to the server and refresh the data in the grid after the server processed the form submittion. The $(form).submit() will be used in the case that your page consist mostly from the form. In the case you submit the data and the page will be refreshed. What you probably really want to do you can implement with respect of $.ajax with type: 'POST' parameter or with respect of its simplified form $.post. You can set the submit event handler (or click handler if you rename the type of the button) and inside the handler you can send the data to the server per $.ajax manually. In the case you can use success handler to reload the grid. Inside of submit event handler you can get the form data with $(form).serialize() and you should return false to prevent standard submitting of the form. See here an example. You should don't forget to define name attribute to all fields of the form which you want send to the server (see here). I don't know exactly which relationship has the form to the grid data, but one more possible
stackexchange
This invention relates generally to the detection of conductors near inductive coupling loops, and more specifically to the detection of cookware on a cooktop or heating surface and determination of the size and/or the temperature of the cookware located thereon. Cookware detection, size determination, and temperature determination features for induction heating cooking appliances provide added convenience to usera as well as allowing an added level of safety to be incorporated into cooking surface control schemes. For example, in some induction cooktops, power is disabled to heating elements until a presence of an item of cookware is detected on the cooktop, therfore providing automatic power control to heating elements while conserving energy and at least partially reducing a likelihood of injury from contact with unoccupied heating elements. In at least one known pan detection system, an induction coil is used and the presence of an item of cookware on the cooking surface induces frequency changes detected in a detection circuit coupled to the controls for operating heating elements. However, electronic components used in such applications are sensitive to heat degradation because the heat generated in a cooking surface environment changes electronic components values and tolerances over time. In addition, during cooking cycles, the electronic components are exposed to fluctuating heat generated in the cooking elements so electronic component values and characteristics fluctuate during the cooking cycle. As applied to the known detection systems, the heat fluctuation in the cooking environment, and thus the fluctuations in component value, induces fluctuations in a detected frequency in the detection circuit. These fluctuations in frequency require a sophisticated control circuit with a particular bandwidth to accurately detect presence of cookware and to control heating elements accordingly. Accordingly, it would therefore be desirable to provide a circuit for accurately detecting cookware presence and size for an induction based cooking system that is not based upon frequency change as the detection mechanism, thereby eliminating the problems associated with fluctuating component values induced by exposure to heat in the cooking environment. In an exemplary embodiment of the invention, a method of detecting the presence of a conductor, for example a piece of cookware, near an inductive coupling loop includes the steps of introducing an excitation signal to a coupling loop, measuring the amount of signal distortion induced in the coupling loop by the excitation signal, and monitoring the harmonic content of the distorted signal. The inductive coupling loop is located within a cooking surface or cooktop, near a heating element. A signal generating circuit is used to generate an excitation signal that is applied to the coupling loop. The effect of a conductor, such as a piece of cookware, is to distort the excitation signal
uspto_backgrounds
Background After signing with D'Leon Records in June 2014, Reyes released her debut single "Muévelo" and scheduled the release her first album for early 2015. From that date to January 2017, the singer released three more singles, one promotional single and featured on Cash Cash's "How To Love" and Spencer Ludwig's "Diggy". In November 2016, it was announced that Reyes' debut studio album would be titled Louder and that it would be dropped in February 2017. Singles Reyes' debut single "Muévelo" was released on August 22, 2014 and featured guest vocals from Puerto Rican rapper Wisin. Reyes co-wrote the "nightclub-friendly anthem" with Wisin, Toby Gad, Lil' Eddie, Eritza Laues, Marissa Jack, and Slikk. The song peaked at number 25 on the Billboard Hot Latin Songs and at number 18 on the Mexico Airplay chart. In Spain, it peaked at number 13 and was certified platinum. "Conmigo (Rest of Your Life)" was released as the album's second single in early 2016. The song has been described as "a breezy, bilingual pop record with an R&B sensibility" and was written and produced by Romanian producer Andrei Mihai, Nuyorican Lil' Eddie and Reyes. The third single, "Solo Yo", which features American singer Prince Royce, was released on January 28, 2016. With "Solo Yo", Reyes became the first solo lead female act to hit No. 1 on the Billboard Latin Pop Songs chart in five years. The last time a woman crowned the chart was in 2011 when Jennifer Lopez spent five weeks atop the chart with "Ven A Bailar". An English version of the song titled "Nobody But Me" was released on March 3, 2016. On October 21, 2016, Reyes released "Llegaste Tú" featuring Reykon as the album's fourth single. Promotional singles "Louder! (Love Is Loud)" featuring Canadian artist Francesco Yates and trumpeter Spencer Ludwig, was released as a promotional single on September 2, 2016. The "upbeat and energetic Spanglish track" was the theme song for Garnier Fructis Mexico #NoCortes campaign. Track listing Charts Certifications Louder Tour Reyes embarked on
wikipedia_en
It is seen that at least in the concrete case under consideration the second order perturbation correction (A.8) gives excellent approximation of TD transition energies for all states. In some cases use of perturbation theory to evaluate excitation energies may be computationally more efficient than the direct diagonalization of either non-symmetric Hamiltonian real matrix or non-Hermitian Schr$\rm \ddot{o}$dinger-type complex matrix. However, to make reliable conclusion about applicability of perturbation approach, heavy numerical testing is required. [**Derivatives of Gram-Schmidt**]{} [**Parametrization Mapping** ]{} Matrix $${\rm g(Z)}=\left (\begin{array}{c} {\rm I}_p\\ {\rm Z} \end{array}\right ){\rm W(Z)} \eqno{(B.1)}$$ involved in Eq.(\[GS\]) satisfies the orthogonality condition $$\left [{\rm g(Z)}\right ]^{\dagger}{\rm g(Z)}={\rm I}_p \eqno{(B.2)}$$ To simplify the notations, we agree to omit, when possible, explicit indication on dependence of matrices $\rm W$ and $\rm g$ on $\rm Z=X+iY$. Differentiation of Eq.(B.2) gives $$\frac {\partial {\rm W}^{\dagger}}{\partial X_{\nu\mu}} \left [{\rm W}^{\dagger}\right ]^{-1}+{\rm W}^{-1}\frac {\partial {\rm W}}{\partial X_{\nu\mu}}=-{\rm W}^{\dagger}{\rm J}^{\dagger}_{\nu\mu}{\rm g}-{\rm g}^{\dagger}{\rm J}_{\nu\mu}{\rm W}\eqno{(B.3a)}$$ $$\frac {\partial {\rm W}^{\dagger}}{\partial Y_{\nu\mu}} \left [{\rm W}^{\dagger}\right ]^{-1}+{\rm W}^{-1}\frac {\partial {\rm W}}{\partial Y_{\nu\mu}}={\rm i}{\rm W}^{\dagger}{\rm J}^{\dagger}_{\nu\mu}{\rm g}-{\rm i}{\rm g}^{\dagger}{\rm J}_{\nu\mu}{\rm W}\quad \eqno{(B.3b)}$$ where basis matrices ${\rm J}_{\nu\mu}$ and ${\rm i}{\rm J}_{\nu\mu}$ are defined by $$\frac {\partial}{\partial X_{\nu\mu}}\left (\begin{array}{c} {\rm I}_p\\
arxiv
/* These files are distributed with PhotoFlow - http://aferrero2707.github.io/PhotoFlow/ */ #ifndef CACHE_BUFFER_H #define CACHE_BUFFER_H #include <math.h> #include <string> #include <list> #include <vector> #include <iostream> #include <fstream> #include <vips/vips.h> //#include <vips/vips> #include "pftypes.hh" #include "format_info.hh" #include "property.hh" #include "imagepyramid.hh" namespace PF { class CacheBuffer { // Image to be cached VipsImage* image; // Image associate to the disk buffer VipsImage* cached; ImagePyramid pyramid; std::string filename; int fd; guchar* memarray; bool memarray_assigned; // Flag indicating if the cache buffer has already been initialized // Used by the layer manager to write buffers upon image loading/exporting bool initialized; //Flag indicating if the processing is completed bool completed; // Coordinates of the tile being processed int step_x, step_y; void step_cb(int x0, int y0, guchar* buf); public: CacheBuffer(); virtual ~CacheBuffer() { if( cached ) PF_UNREF( cached, "~CacheBuffer() cached image unref" ); } bool is_initialized() { return initialized; } void set_initialized( bool flag ) { initialized = flag; } VipsImage* get_image() { return image; } void set_image( VipsImage* img ) { image = img; } ImagePyramid& get_pyramid() { return pyramid; } void reset( bool reinitialize=false ); bool is_completed() { return completed; } // Save data tile-by-tile void step(); // Save all data to file void write();
github
Speaking of passion, remember what makes your young heart beat. Music, words, writing, photography, powerful movies that highlight the beautiful parts of life. Don't get trapped in the mires of your everyday. Don't let the tragedy of this thing we call life paint a picture that is full of shadows. Let it go. Take off your headset and drown it out with words and life and sunlight and music and great food and lots of laughs. You're going to get off course, maybe not all the time, but sometimes you'll forget to come back to the middle. You won't get it now, but you'll get it after this great man is gone from the earth and you watch his work to understand why he will be so missed. This is how you come back to the middle, young lady. Let love in. Just do it. Let someone love you, and not just from a distance. Don't be afraid to get your heart broken. Put out of your mind that you could never date that kind of guy, or be that sort of girlfriend, or survive that kind of love. You'll box yourself in, you'll blind yourself to the perfect imperfections of the ones who might be the exact mirror you've been looking for. Don't forget to love yourself a little too. Move your body. Dance, do yoga, run, sweat, bend, shift, gyrate, just shake it off. Someday in the future you'll find yourself shaking and sweating and wondering why you never thought you were strong enough to run in a relay or hold a pose or climb a steep hill, and you'll love it. Then you'll lose it and wonder if you'll ever recover from pushing your body too far and you'll realize that you forgot to say no and your body said it for you. It's a hard lesson, it's painful and it will drop you to your knees and keep you up at night, but the beauty of it all is that you can still move. And all it takes is to move little and then you can move big, but you'll never lose as long as you're still moving. Move yourself, Love. Find your sexy. Not your slutty. Not your sleazy. Not your trying too hard. Find your own version of sexy. It's not what you think it is. It's confidence. It's subtle. It's comfortable in your own skin. It's genuine. It's your shoulder peeping out your shirt
pile-cc
-p + 2 Let x(w) = -2*w**3 + 4*w**2 + 4*w - 1. Let k(m) = -7*m**3 + 11*m**2 + 11*m - 3. Give -4*k(d) + 11*x(d). 6*d**3 + 1 Let q(o) = o**3 + o**2 + o + 1. Let u(k) = 8*k**3 + 4*k**2 + 6*k + 5. Calculate 5*q(z) - u(z). -3*z**3 + z**2 - z Let m(a) = 2*a - 8. Let q(z) = 3*z - 2*z + z - 7. Let s be 12/10*(-840)/(-48). Suppose 5*c = p - 25, 4*c - p + s - 2 = 0. What is c*q(r) + 5*m(r)? -2*r + 2 Let y(d) = -2*d + 7. Suppose -3*a = 3*v - 15, -5*v = -4*v - 5*a + 25. Let j(x) = -1 + 3*x - x - 5 + v*x. Give -5*j(p) - 4*y(p). -2*p + 2 Let d(a) = a + 1. Suppose w - 3 = u + 1, -u + 2 = -3*w. Let v be d(u). Let x(i) = 0*i + i - 2*i. Let f(b) = 7*b - 1. What is v*x(c) - f(c)? -c + 1 Let z(s) be the first derivative of 1 + 9 - 4 - 4 - s. Let o(w) = -w + 5. Calculate -2*o(u) - 11*z(u). 2*u + 1 Let s(l) = 5*l**2 + 11*l - 8. Let k(h) = -3*h**2 - 6*h + 4. Determine 11*k(y) + 6*s(y). -3*y**2 -
dm_mathematics
We will be scheduling our next general meeting for mid October. Also, we have finalized the dates for the Annual Retreat and will be sending out packets with all the details next week. DJ and I are working on the agenda so if you have a specific topic you would like covered please let us know. As always, please send me an email or give me a call if you have any concerns or questions about the letter or any other matter.
enron_emails
FACTS In 1986, Congress expanded Medicaid coverage of pregnancy-related medical care to low-income women who did not otherwise qualify for Medicaid. Women during pregnancy and the 60-day postpartum period who are not eligible under any other Medicaid program and whose income is up to 133 percent of the federal poverty level or, at the State's option, up to 185 percent of the federal poverty level, can apply for limited prenatal and postpartum health care services. 42 U.S.C. §§ 1396a(l)(1) & (2); 1396a(a)(10)(A)(i)(IV). New York State has exercised the option to provide for coverage up to 185 percent of the federal poverty level. Medical coverage in this program is different from that offered by conventional Medicaid, in that it is limited to prenatal, delivery, postpartum care, and family-planning services. 42 U.S.C. § 1396a(a)(10). There is no coverage for other kinds of medical care not related to pregnancy or childbirth. However, households which continue to meet the eligibility standards under the Act after the baby's birth may obtain continued health care under Medicaid's Infant Care Program until the infant is one year old. 42 U.S.C. § 1396a(l)(1)(B). For conventional Medicaid coverage, eligible applicants must cooperate with the State Medicaid agency to obtain financial support from third parties who may be legally responsible to support them. Until 1990, applicants could be exempted from this requirement only "[if] the individual is found to have good cause for refusing to cooperate...." 42 U.S.C. § 1396k(a)(1)(B) (1986). However, in 1990, Congress amended § 1396k to add another exemption to the "good-cause" exception. Recognizing that the cooperation requirement created a barrier for some pregnant women who seek prenatal care, Congress decided to exempt women who receive *487 only the limited pregnancy-related medical care coverage, as described in § 1396a(a)(10)(A)(i)(IV). 42 U.S.C. § 1396k(a)(1)(B) (1990).[1] In October 1991, Jodi Perry applied for Medicaid benefits to cover the costs of her pregnancy-related medical care. She was told she was ineligible for comprehensive Medicaid coverage because of her income level, but could receive pregnancy-related benefits for the duration of her pregnancy, including 60 days postpartum
freelaw
------ muzster I remember those novice days with fond memories. I've observed, in the twilight hours or when I'm playing with my kids, that I am attracted to things that make me feel a novice. However, this is not compatible with my day time job, where my paid expertise is often required. _sigh_ It would be interesting to see the graph of the careers stages with happiness overlaid. Source: [http://www.bennorthrop.com/Essays/2016/career-stages- program...](http://www.bennorthrop.com/Essays/2016/career-stages- programmer.png) ------ mti27 "And then one day you find, ten years got behind you. No one told you when to run, you missed the starting gun..." To the author: Hang in there, man! You're just feeling the time crunch, now that you have kids and other responsibilities. Based on your age, it would have been the mid-1990s when your professional career started. Back then, the economy was a lot better and outsourcing hadn't yet taken over at large companies. It's a little more dog-eat-dog economically, but your brain probably still works fine. Just take a breath and keep going. ------ partycoder Well, first of all, new shiny things are not really new at all. The principles behind them have been around for decades. Learning 30 different imperative languages (c, pascal, ada and descendants) might not add as much value as learning an imperative language, a functional language, a logic programming language, a language emphasizing concurrency (go, erlang), etc... meaning, learning paradigms and high level design constructs not syntax. Try to stay in touch with new paradigms, instead of just new applications of them. ------ euske I recently found that every programmer has to discover what it is like to create a new exciting thing and watch it fades into obscurity. i.e. Life is all about reinventing your own wheel. ------ sbt The second advice, investing in durable skills, is key. In addition to what the author mentions, I would point out that more change
hackernews
In recent years, pain research has made revolutionary advances at levels ranging from genes to behavior. However, one basic level of organization that has proved particularly resistant to analysis is the intrinsic circuitry underlying pain transmission and modulation within the first central relay area, the spinal dorsal horn. There is much evidence that changes in intrinsic dorsal horn interneurons contribute to plasticity underlying inflammatory and neuropathic pain, but further understanding has been limited by a dearth of methods for studying this intrinsic circuitry. In recent years a novel technique
nih_exporter
The development of advanced noninvasive techniques to image the human brain has enabled the demonstration of structural plasticity during adulthood in response to motor learning. Understanding the basic mechanisms of structural plasticity in the context of motor learning is essential to improve motor rehabilitation in stroke patients. Here, we review and discuss the emerging evidence for motor-learning-related structural plasticity and the implications for stroke rehabilitation. In the clinical context, a few studies have started to assess the effects of rehabilitation on structural measures to understand recovery poststroke and additionally
pubmed_abstracts
Because large weights may cause anomalies in analysis, the weights were assessed for any outliers (Austin and Stuart [@CR1]). We examined the range of weights and decided to trim weights based on distribution. Trimmed weights exclude those observations that had a weight below 1% or above 99% of the distribution of weights for the treatment and control groups separately. This method dropped 1.8% of observations, or 211 of the 11,530 TAY-ASD who had information on receipt of PSE training services. Trimming weights allowed for better overlap between propensity scores of the treatment and control groups. We then used trimmed weighted logistic regression to model the impact of PSE training on exit with employment, while presenting associations with other covariates as well. There is some discussion as to whether covariates should be included in the outcome model when determining the relationship between the treatment (PSE training services) and outcome (exit with employment). Some suggest that including covariates makes the model doubly robust, allowing for more misspecification and the exclusion of unobserved data while giving the best chance for a properly specified model (Bang and Robins [@CR2]; Hullsiek and Louis [@CR13]). Therefore we included additional covariates in the outcome model. All analyses were conducted in Stata 15, propensity score calculation used the *twang* add on for Stata. Results {#Sec5} ======= Research Aim 1: Prevalence of Receipt of PSE Training Services Among TAY-ASD Compared to TAY with Other Disabilities {#Sec6} -------------------------------------------------------------------------------------------------------------------- Table [1](#Tab1){ref-type="table"} displays the characteristics of TAY. The mean age of TAY-ASD was 19 years at the time of application to services. More TAY-ASD were male (83.1%) and white (85.1%) and fewer Hispanic (6.8%) than TAY with IDD (57.0% male, 65.3% white, 10.4% Hispanic) or all other TAY (57.7% male, 73.0% white, 14.8% Hispanic). Fewer TAY-ASD received SSDI (5.7%) or SSI (29.0%) at application than TAY with IDD (SSDI 7.2%, SSI 40.5%) but more than all other TAY (SSDI 3.5%, SSI 14.4%). TAY-ASD spent less time
pubmed_central
if (sponser.value == "NH") { document.getElementById('nameofperson').style.display = "none"; document.getElementById('nameofpersonvalue').style.display = "none"; document.getElementById('address').style.display = "none"; document.getElementById('th1').style.display = "none"; document.getElementById('th8').style.display = "table-row"; } if (sponser.value == "Y") { document.getElementById('nameofperson').style.display = "none"; document.getElementById('nameofpersonvalue').style.display = "none"; document.getElementById('address').style.display = "none"; } } The function is called from the HTML with an onclick event which looks like this: <input type="radio" name="IPQ_FUND1" id="IPQ_FUND1" value="Y" checked="checked" onclick="addSponsership(this);"/> I now want to call all of these functions using the onload event on the body element. However, I am unsure how to do this. Example: function callAllOtherFunctions() { addSponsership(sponser) addSponsership2(sponser) addSponsership3(sponser) etc... } The problem with this is that I can't find a way to refer to the specific elements whose values need to be checked. Ideally I need to find a solution to this without editing the original functions written by my colleague. I tried to do it individually by creating another function that looked like this: function addSponsershipLoad(inputID){ sponser = document.getElementById(inputID); addSponsership(sponser); } and editing the body tag to look like this: <body onload="addSponserShipLoad('IPQ_FUND1');"> but despite the console not showing any errors, this didn't work. So, I know I'm probably being quite thick and the solution will be simple, but please help if you can. A: You don't have to put everything in variables: addSponsership(document.getElementById('IPQ_FUND1'));
stackexchange
Regenerative amplifiers are generally used to provide relatively strong amplification of laser pulses. Multiple passes through the gain medium are achieved by placing the gain medium in an optical resonator, together with an optical switch that may be formed by an electro-optic modulator and one or more polarizers. The number of round trips in the resonator is controlled with the optical switch and, when this number is large, a high overall amplification factor (i.e., gain) can be achieved. While these regenerative amplifiers provide significant gain, they are often difficult to implement due to their complex cavities. Moreover, switching of the laser pulses within the cavity usually decreases the achievable pulse energies or beam due to nonlinear propagation effects within the switch. Additionally, regenerative amplifiers, under some operating conditions, suffer from chaotic or multi-stable operation. In these operating conditions, the residual gain in the gain medium after energy extraction significantly affects the gain that can be imparted on a subsequent signal pulse. Regenerative amplifiers also generally amplify one pulse at a time. Therefore, the repetition rate of the laser system is less than the reciprocal of the time between the injection and ejection of each amplified pulse. Another concern in high power laser systems regards heat. High average power laser systems typically produce heat and most laser architectures are designed with this in mind because high temperatures within a gain medium can reduce gain and/or cause thermo-mechanical strains that result in stress-induced birefringence. Temperature distributions in a gain medium can also lead to phase distortions which result in poor laser beam quality. At more extreme temperatures, damage to the gain material or optical coatings can occur. High temperatures within a laser system can also lead to mechanical movements that result in optical misalignment. In order to efficiently extract heat from a solid gain medium, the fraction of cooled surface area per heated volume is generally maximized. Two geometries that have been used for high power laser systems include fibers and thin disks. In the case of fibers, two dimensions are minimized and one dimension is maximized so that a large surface area to volume ratio can be obtained for efficient cooling. Additionally, fiber amplifier geometries support very large gain-length products. Fiber amplifiers, however, are not optimal for high-power short pulses because high intensities may result from transmission of laser pulse energy through a very small cross section of an optical fiber. For high pulse powers and small cross-sections, the peak intensity can be extremely high and lead to deleterious nonlinear propagation effects. One solution for thermal management of pulsed laser operation
uspto_backgrounds
Composition of peals is a specialised and highly complicated area of change ringing, as it involves composing a peal according to the rules. The "Conductor" of the peal has to: Control and ring their own bell in the correct sequence Correct other ringers if they go wrong Call the "bobs" and "singles" which are the "composition" – the equivalent of a musical score – that ensures the correct changes are rung in the correct sequence. A peal can fail at any point if there is a mix-up of bells which cannot be put right; this can happen only minutes from the end. Popularity of 10-bell methods According to the best available knowledge in 2017, 6,929 peals of Grandsire Caters (on 10 bells) were rung in the 300 years following 11 January 1711. Grandsire Caters was the leading 10-bell method in each decade from 1711 to 1890, but Stedman Caters has proved more popular recently and on 9 July 2010 its cumulative peal total from 1711 pulled ahead of the running Grandsire total. Long-length peals Another area of peal ringing is that of long-length peals. These involve ringing for far longer than an ordinary peal, up to 17 hours. The difficulties of ringing ordinary peals are magnified in these performances, as are the difficulties of composing them. One challenge to ringers is to ring 'the extent', which on eight bells is 40320 changes. The last time this was rung on tower bells, it took 18 hours. Raising and lowering in peal "Raising in peal" does not refer to ringing a peal, but is the process where a band of ringers increases the swing of tower bells from mouth down to mouth upwards while keeping them ringing in rounds. The opposite process is "lowering in peal", where the swing of the bells is gradually reduced until they are at rest mouth downwards, again keeping the bells ringing in rounds throughout. Quarter peal Quarter peals are also commonly rung, and are popular for service ringing, where a full peal would be time-consuming. These generally meet most of the rules for a peal, but need be only a quarter the length (i.e. at least 1260 or 1250 changes, depending on the number of bells). Records of
wikipedia_en
(ii) $\|u\|_{C^{\frac{(1+\theta)}{2},1+\theta}(Q)}+\| v\|_{C^{\frac{(1+\theta)}{2},1+\theta}(Q^\infty)}+\|h\|_{C^{1+\frac{\theta}{2}}([0,T])}\leq K$, where $0<\theta<1$ is the Hölder exponent in , $$\begin{array}{c} Q=\{(t,x)\in \mathbb{R}^{2},\text{ such that }t\in[0,T] \text{ and }x\in[0,h(t)]\},\\ Q^\infty=\{(t,x)\in \mathbb{R}^{2}, \text{ such that } t\in[0,T] \text{ and }x\in[0,+\infty)\},\end{array}$$ $K$ and $T$ are constants that depend only on $h_{0}$, $\theta$, $\| u_{0}\|_{C^{2}([0,h_{0}])}$ and $\|v_{0}\|_{C^{2}([0,+\infty))}$. The next result provides some bounds on the solutions to system with initial conditions . \[le2.2\] Let $(u,v,h)$ be a solution of for $t\in [0,T]$ for some $T>0$. Then, (i) $0<u(t,x)\leq M_{1}$ for all $t\in (0,T]$ and $x\in [0,h(t))$, where $$M_1:=\max\left\{\frac{\|b_{1}\|_{L^{\infty}([0,\infty))}}{\delta_{1}}, \|u_{0}\|_{L^{\infty}([0,h_{0}])}\right\}.$$ (ii) $0<v(t,x)\leq M_{2}$ for all $t\in (0,T]$ and $x\in [0, +\infty)$, where $$M_2:=\max\left\{\frac{\|b_{2}\|_{L^{\infty}([0,\infty))}}{\delta_{2}}, \|v_{0}\|_{L^{\infty}([0,+\infty))}\right\}.$$ (iii) $0< h'(t)\leq \Lambda$ for all $t\in (
arxiv
<id name="conceptSourceId" type="java.lang.Integer" column="concept_source_id" unsaved-value="0"> <generator class="native"> <param name="sequence">concept_reference_source_concept_source_id_seq</param> </generator> </id> <property name="uuid" type="java.lang.String" column="uuid" length="38" unique="true" /> <property name="name" type="java.lang.String" column="name" length="50" not-null="true" /> <property name="description" type="java.lang.String" column="description" length="1024" not-null="true" /> <property name="hl7Code" type="java.lang.String" column="hl7_code" length="50" /> <property name="uniqueId" type="java.lang.String" column="unique_id" length="250" unique="true" /> <property name="dateCreated" type="java.util.Date" column="date_created" not-null="true" length="19" /> <property name="retired" type="boolean" column="retired" not-null="true"/> <property name="dateRetired" type="java.util.Date" column="date_retired" length="19" /> <property name="retireReason" type="java.lang.String" column="retire_reason" length="255" /> <!-- Associations --> <!-- bi-directional many-to-one association to User --> <many-to-one name="creator" class="org.openmrs.User" not-null="true"> <column name="creator" /> </many-to-one> <many-to-one name="retiredBy" class="org.openmrs.User" column="retired_by" /> <many-to-one name="changedBy" class="org.openmrs.User" column="changed_by"/> <property name="dateChanged" type="java.util.
github
There's a clue to the problem in that slick and showy word "smart". As the cyber-sceptic Evgeny Morozov pointed out this month, in an article at edge.org, Silicon Valley loves nothing more than proposing "smart" solutions to problems such as crime, voter apathy or climate change. Yet the word blurs a crucial distinction: a smart solution may be ingenious, but it doesn't follow that implementing it will necessarily be for the best. We can persuade people to vote, some techno-reformers argue, using clever incentives, such as shopping discounts or video game-style prizes. But should we, if it risks coarsening democracy, eroding the role of argument and deliberation in persuading people to vote? The answer may be "yes", of course. But Morozov's point is that we fail to ask such questions in the first place. When it comes to "working smarter", the same kind of problem arises: what if doing things more "efficiently", in a superficial sense, results in doing them worse? There's evidence to suggest that we need to daydream; perhaps we also need those moments of afternoon lassitude and aimless conversations by the office microwave. Creative work, especially, depends on a kind of inefficiency. Inevitably, the scandal and schadenfreude surrounding Jonah Lehrer's book Imagine has all but drowned out its fundamental insight, but it's a good one: creative breakthroughs depend on being stumped and feeling frustrated. Make the path to them too smooth, and you get lower-quality breakthroughs. The other, more pressing hazard concerns what you'll do with all the time you free up by working smarter: the chances are you – or your boss – will simply fill it with more work. This is the problem with most "smarter, not harder" advice: it's great on the working-more-efficiently part, but it assumes that working less hard will follow automatically. In reality, it won't. So what's the answer? On one level, it's a question of techniques: scheduling specific social activities starting soon after work, say, to ensure your increased efficiency pays off in increased leisure. But on another level, the demand for ever more output is structural, built into our jobs and the economy. Clever techniques alone won't change that. And so the danger is that we just work smarter and harder. And harder, and harder, until
pile-cc
1, -1, p Let q(o) = o**2 - o - 2. Let p be q(2). Let m = -1 + p. Suppose -l = t - 8, -l = t + t - 11. Sort 0, m, l. m, 0, l Let u = 15/13 + -144/91. Sort u, 1/2, -4 in descending order. 1/2, u, -4 Let s = -0.08 + 0.08. Let c = s + -0.2. Sort -2/7, c, 0.1 in descending order. 0.1, c, -2/7 Let g(p) = -p**3. Let m be g(0). Let b(f) = 3*f**3 + f**2 + f. Let s be b(2). Let w be 2/15 - 64/s. Put m, w, -1 in descending order. m, -1, w Suppose 0 = -5*c - 0 + 30. Let h be c/(-39) - 126/26. Sort h, 5, -3. h, -3, 5 Let u(m) = -m**3 + 13*m**2 - m + 16. Let g be u(13). Suppose 2*z = g*z - 5. Sort -4, 4, z in decreasing order. z, 4, -4 Suppose 5*r - 4*r = 4, k - 15 = -3*r. Put -5, 1, 4, k in increasing order. -5, 1, k, 4 Suppose -61 = 8*o + 59. Sort -2, o, 1 in ascending order. o, -2, 1 Let w(j) = j**3 + 6*j**2 - 7*j + 2. Let z be w(-7). Put 0, z, 1, 3 in decreasing order. 3, z, 1, 0 Suppose 0*a - 3*a - 36 = 0. Let q be 1 - (0 + a/(-3)). Sort q, 4, -2 in decreasing order. 4, -2, q Let c = 0.09 - 0.07. Let y = -0.52 + c. Suppose i =
dm_mathematics
Debra Perlingiere Enron North America Corp. Legal Department 1400 Smith Street, EB 3885 Houston, Texas 77002 [email protected] Phone 713-853-7658 Fax 713-646-3490 ----- Forwarded by Debra Perlingiere/HOU/ECT on 03/14/2001 09:46 AM ----- Genia FitzGerald 03/07/2001 10:26 AM
enron_emails
The principles that control in our case are set forth in Unger v. Campau (1956) 142 Cal.App.2d 722 [298 P.2d 891], wherein the defendants sold the plaintiff a dwelling which they had listed as having three separate rental units and *6 which they had told the plaintiff could easily be used for income purposes. In actuality, one of the rental units had been constructed in an illegal manner and without inspection permits, and could not be legally rented. The court upheld the trial court's finding that the manner in which the property had been listed and the defendants' statement that it could easily be rented constituted misrepresentations upon which the plaintiff was justified in relying. As to the question of whether the defendants knew that they were required to obtain permits, the court noted that there was evidence that one of the defendants had worked as a hod carrier, bricklayer and plasterer, and that he had previously obtained a permit in connection with other work performed by him. He had also testified that he knew a permit was necessary for work costing $200 or more. The court thus concluded that the question of knowledge was one of fact and that there was ample evidence to support the trial court's finding of actual knowledge. In the case at bar, the representations made by the Cirias and their agent, Mr. Vagin, were almost identical to those made in the Unger case. Granting there was evidence on both sides of the matter, the conflict in the evidence was for the trier of facts. Hence, it cannot be said as a matter of law that the lower court erred in finding that the Cirias knew of the need for permits. [3] Appellants next contend that the trial court was without power to hold Paul T. Ciria and Virginia Shank liable as constructive trustees of the note and deed of trust in the absence of any showing that these defendants participated in or had knowledge of the fraud of their parents. Appellants further contend that respondents' failure to file a claim in the estate of Rachel Ciria precluded them from offsetting their damages against the interests of Paul T. Ciria and Virginia Shank. Neither of these arguments is meritorious. While the trial court correctly found that Paul T. Ciria and Virginia Shank "did not have any part in any transaction leading up to the sale of said real property to plaintiffs," it does not follow, however, that the court erred in holding these defendants liable as constructive trustees of their interests in the note and deed of trust
freelaw
* Nintendo declares yet another year of losses, doesn't die (yet) * The year of Linux on the Desktop (just kidding) ------ unexpected 1) RIM will be bought. 2) Google will fold ChromeOS and roll up everything into variations of Android. ~~~ math On the other side of the trade ... some RIM related commentary on seeking alpha by one of the people I pay attention to, Rocco Pendola: "don't expect anybody, particularly Amazon, to buy RIM anytime soon.". [http://seekingalpha.com/article/315331-amazon-making- blackbe...](http://seekingalpha.com/article/315331-amazon-making-blackberry- cool-again) ------ math Our latest project will give you lots of financial predictions, many for 2012 (though you can't filter by that explicitly yet): <http://backrecord.com> Early days, but if you're into this sort of thing worth checking out.. ------ booduh \- The year of the startup. \- Massive government policy changes. \- Revolution in conscious dream and mind (self) control. \- Apple TV sucks. \- Facebook gets lucky. And of course... \- My startup is the most viral web app of the year! ------ willvarfar Native Client (NaCL) will power the next wave of social games. Adobe Creative Suite will support an NaCL target and Flash will be superceded whilst Adobe get a new boost of adoption on the tools front ~~~ charliesome I hope NaCl doesn't gain any traction. It really is a step backwards. ------ buymorechuck Facebook continues work on their own fork of Android towards releasing a phone and Facebook mobile app platform. Perhaps an IPO to coincide with it. ------ yurylifshits 10x-100x growth in enrollment into online classes from top universities (like Stanford classes) Non-TED lecture to get 5M views on Youtube ------ teja1990 Android will gain more market and still struggles to make more money than iOS. I'll start my startup and still continue reading HN :D ------ colinm Steak-in-
hackernews
In our 1 M GWAS, 4 of the 10 SNPs most significantly associated with body mass index (BMI) mapped near or within the MAP2K3 gene. Fine mapping of this region revealed that specific regions of this locus were duplicated, and a large number of the database SNPs from this region were false SNPs. Validated SNPs that mapped uniquely to the MAP2K3 locus were genotyped in 3500 full-heritage Pima Indians and replication was assessed in a second sample of 3800
nih_exporter
Effects of selenium deficiency on fatty acid metabolism in rats fed fish oil-enriched diets. The hepatic fatty acid metabolism was investigated in rats stressed by selenium deficiency and enhanced fish oil intake. Changes in the composition of lipids, peroxides, and fatty acids were studied in the liver of rats fed either a Sedeficient (8 microg Se/kg) or a Se-adequate (300 microg Se/kg) diet, both rich in n-3 fatty acid-containing fish oil (100
pubmed_abstracts
As much of the world has gone into complete lockdown, woefully unprepared, many countries have turned to South Korea for answers, given its handling of COVID‐19. Rapid and widespread testing, expansive surveillance assemblage and selected quarantine practices are upheld by many countries and public health professionals as superb, a model to adopt. But this is not South Korea's only lesson. Indeed, the world is on edge, scrambling in the here and now, but trying to figure out what happens to sociality going forward. Five years prior, South Korea found itself mid‐epidemic, facing a different coronavirus. In the aftermath of the 2015 Middle East Respiratory Syndrome Coronavirus (MERS‐CoV) outbreak in South Korea, queer and HIV/AIDS activists gathered to reflect on the government's and society's treatment of infected individuals as vectors of disease rather than as people. Activists demonstrated how this viropolitical stance mirrored the treatment of people living with HIV/AIDS in South Korea: they became more disease than person, threatening South Korean bodies and making South Korea itself impure. One particular activist at the gathering stated that South Korea should *not* aim for purity or absolute cleanliness to keep citizens safe. That's impossible, and results in catastrophic social and psychological effects for those deemed impure and unclean. Rather, the activist claimed, we need to find ways for infected and non‐infected individuals to live together, both socially and spatially. When kinship and social relations are predicated on consanguine purity, the mere presence of a virus can potentially upend an entire social and affective system of belonging. For activists, that epidemic embodied, quite literally, fundamental problems in South Korean kinship, social relations and belonging. The problems of sociality and belonging are now front and centre in the current pandemic, as quarantines, isolation and social distancing have blanketed much of the world. The Herculean global effort of viral containment and cleanliness -- discourses of face masks and social distancing -- though undeniably important, will have lasting effects on how we live with one another. This was the fear of those South Korean activists after the MERS‐CoV outbreak, as what underlined public health discourse and practice were stigmas of impurity. Living together, then, confronts stigmas of impurity, and purity's embeddedness in sociality and belonging. The virus, facilitating for many a reprioritisation of one's life, allows a broader reassessment
pubmed_central
I got events that happen at locations: class Event(models.Model): title = models.CharField(max_length=200) date_published = models.DateTimeField('published date',default=datetime.now, blank=True) date_start = models.DateTimeField('start date') date_end = models.DateTimeField('end date') def __unicode__(self): return self.title description = models.TextField() price = models.IntegerField(null=True, blank=True) tags = TaggableManager() location = models.ForeignKey(Location, blank=False) class Location(models.Model): location_title = models.CharField(max_length=200) location_date_published = models.DateTimeField('published date',default=datetime.now, blank=True) location_latitude = models.CharField(max_length=200) location_longitude = models.CharField(max_length=200) location_address = models.CharField(max_length=200) location_city = models.CharField(max_length=200) location_zipcode = models.CharField(max_length=200) location_state = models.CharField(max_length=200) location_country = models.CharField(max_length=200) location_description = models.TextField() def __unicode__(self): return u'%s' % (self.location_title) I can get the results of all via: class EventSerializer(serializers.HyperlinkedModelSerializer): id = serializers.Field() class Meta: model = Event depth = 2 fields = ('url','id','title','date_start','date_end','description', 'price', 'location') Which outputs: { "url": "http://localhost:8000/api/event/3/", "id": 3, "title": "Testing", "date_start": "2013-03-10T20:19:00Z", "date_end": "2013-03-10T20:19:00Z",
stackexchange
1. Field of the Invention This invention relates in general to treadmills and in particular to an improved shock absorbing treadmill which provides in use reduced landing forces to a runner's foot while simultaneously providing a substantially flat, stable running surface. 2. Description of the Prior Art The art has provided treadmills in response to demand of walkers, joggers and runners and the medical profession for a device which may be used, especially indoors, for exercise where outdoor walking, jogging or running is not enjoyable or practical. A problem with running or jogging as an exercise to strengthen the cardiovascular system relates to the possibility of impact injury to feet, ankles and knees caused by the force of the runner's foot striking an unyielding surface, such as street pavement. Prior treadmill designs have recognized this problem and have attempted to solve it in a number of ways. For example, U.S. Pat. No. 4,614,337 of Schomenberger discloses a treadmill with a flat top surface covered with a resilient surface such as foam rubber, carpeting or the like. Another example is U.S. Pat. No. 4,548,405 to Lee et al which discloses a trampoline like top surface for a treadmill. U.S. Pat. No. 4,350,336 to Hanford provides a treadmill having a frame to which rollers are attached which carry an endless tread belt. The belt moves above a platform disposed beneath the running portion of the belt. The platform is supported by longitudinal platform rails which are supported at one end by a lateral frame member which is secured to the frame. The platform is supported at its other end by shock absorbing members attached to the longitudina1 rails. The shock absorbing member may be moved longitudinally with respect to the frame. The shock absorbing member absorbs shock directly of the platform as a runner exercises on the treadmill belt above. The platform flexes longitudinally as it pivots at one end and is shock absorbingly supported at its other end. Although an admirable improvement in the art of shock absorbing treadmills, the Hanford treadmill does not provide an adequately stable running surface. The platform is shock absorbingly supported, but the endless tread belt is not. The belt rollers are both supported directly by the frame. As a result, the belt runs over the platform with sufficient slack in it to allow the platform beneath it to move downwardly in response to the impact of a runner's foot. The slack in the
uspto_backgrounds
The MBA Programme has one of the world's largest international exchange programmes. Each year approximately 35 per cent of second-year MBAs spend a term abroad at one of over 30 partner schools, including NYU Stern School of Business, IESE Business School, Booth School of Business of The University of Chicago, The Wharton School of the University of Pennsylvania, UCLA Anderson School of Management, the MIT Sloan School of Management, Tuck School of Business at Dartmouth College, Columbia Business School, Kellogg School of Management at Northwestern University, Haas School of Business at UC Berkeley, McDonough School of Business at Georgetown University, Indian School of Business among others. Executive MBA The school offers four Executive (part-time) MBA degrees, which are completed in 16–20 months. At an academic level, the school offers the same degree to both Executive (part-time) and full-time MBA students. The programmes involve very similar core courses to the full-time MBA, international field work and a wide range of elective courses. The course ends with a capstone together with company project or management report. Executive MBA (London). Executive MBA (Dubai). The programme begins with an orientation week in London. Following this, students take 10 core modules, which are taught in a four- or five-day block each month in Dubai. Students then undertake electives, which are primarily offered in London, and an international assignment. Two additional core modules take place in London. EMBA-Global Americas and Europe. A further 140 executives are enrolled in the dual-degree EMBA-Global Programme. It is taught in partnership with Columbia Business School. Graduates are awarded degrees from both universities. The first year involves week-long modules each month alternating between London and New York. In the second year, students select from the full range of electives available at the participating schools. EMBA-Global Asia'''. launched in 2008 jointly with Hong Kong University and Columbia. Teaching takes place at all three business schools. While the first year is modelled on the transatlantic EMBA-Global, the school states that because "EMBA-Global Asia is designed for people who have or will have significant trans-national responsibilities, all courses reflect a greater proportion of global material". Sloan Masters in Leadership and Strategy The Sloan Fellowship was established in 1968 and is a master's degree programme designed for senior executives, accomplished professionals and entrepreneurs with significant experience
wikipedia_en
In the following we want to demonstrate on the examples of two classes of hybrid EoS models under which conditions the interesting phenomenon of twins at high compact star masses of $\sim 2~M_\odot$ may be obtained. The first one is a phenomenological ansatz Zdunik, Haensel [@Zdunik:2012dj], Alford, Han and Prakash [@Alford:2013aca] which we call the ZHAHP scheme. The second one is based on a QCD motivated, microscopic EoS obtained within a nonlocal Polyakov-NJL model, see [@Blaschke:2013rma] and references therein. The ZHAHP scheme ---------------- A first order phase transition in neutron star matter can take place just as in symmetric matter where it is searched for in heavy ion collisions. Adopting the setting of the ZHAHP scheme, we construct hybrid stars with a hybrid EoS composed of a given hadronic EoS, here DD2 [@Typel:1999yq], and a quark matter EoS parametrized by its squared speed of sound $c_{\rm QM}^2$ which pretty well describes [@Zdunik:2012dj] results of a color superconducting NJL model [@Lastowiecki:2011hh] $$\label{eos} P(\varepsilon)= P_{\rm DD2}(\varepsilon)\Theta(\varepsilon_{\rm crit}-\varepsilon) +c_{\rm QM}^2~\varepsilon~\Theta(\varepsilon-\varepsilon_{\rm crit} -\Delta\varepsilon)~.$$ The critical energy density $\varepsilon_{\rm crit}$ and the discontinuity $\Delta\varepsilon$ complete this three-parameter EoS model which is capable of describing compact star sequences with a third family of stars in the mass-radius diagram. For early works on the disconnected, third branch of stable compact stars and the related mass-twin phenomenon, see Refs. [@Gerlach:1968zz; @Kampfer:1981yr; @Schertler:2000xq; @Glendenning:2000gh]. Searching for sequences with twins obeying the $2~M_\odot$ mass constraint [@Demorest:2010bx; @Antoniadis:2013pzd] we obtain a quasi-horizontal hybrid star branch disconnected by an unstable branch from the almost vertical hadron star branch, as a consequence of a strong phase transition. Fig. \[EoS-MR1\] (
arxiv
#define MAVLINK_MSG_ID_LED_CONTROL_CRC 72 #define MAVLINK_MSG_ID_186_CRC 72 #define MAVLINK_MSG_LED_CONTROL_FIELD_CUSTOM_BYTES_LEN 24 #if MAVLINK_COMMAND_24BIT #define MAVLINK_MESSAGE_INFO_LED_CONTROL { \ 186, \ "LED_CONTROL", \ 6, \ { { "target_system", NULL, MAVLINK_TYPE_UINT8_T, 0, 0, offsetof(mavlink_led_control_t, target_system) }, \ { "target_component", NULL, MAVLINK_TYPE_UINT8_T, 0, 1, offsetof(mavlink_led_control_t, target_component) }, \ { "instance", NULL, MAVLINK_TYPE_UINT8_T, 0, 2, offsetof(mavlink_led_control_t, instance) }, \ { "pattern", NULL, MAVLINK_TYPE_UINT8_T, 0, 3, offsetof(mavlink_led_control_t, pattern) }, \ { "custom_len", NULL, MAVLINK_TYPE_UINT8_T, 0, 4, offsetof(mavlink_led_control_t, custom_len) }, \ { "custom_bytes", NULL, MAVLINK_TYPE_UINT8_T, 24, 5, offsetof(mavlink_led_control_t, custom_bytes) }, \ } \ } #else #define MAVLINK_MESSAGE_INFO_LED_CONTROL { \ "LED_CONTROL", \ 6, \ { { "target_system", NULL, MAVLINK_TYPE_UINT8_T, 0, 0, offsetof(mavlink_led_control_t, target_system) }, \ { "target_component", NULL, MAVLINK_TYPE_UINT8_T, 0, 1, offsetof(mavlink_led_control_t, target_component) }, \ { "instance", NULL, MAVLINK_TYPE_UINT8_T, 0, 2,
github
“Bake something special for your neighbor, a loved one, local police or fire station or even a stranger. When you deliver it to this person, take some time to chat with them … Better yet, if you find yourself cooking up a storm, host a dinner, brunch or holiday bake-off at your house.” — Carly Long, international event planning and design firm LLG Events Unearth your inner artist “Instead of buying a present, be creative and make something special and personal from scratch. Have a hand at painting, baking a loaf of bread or making some organic soap.” — Marina Qutab It takes strength to be gentle and kind “Spend a day doing random acts of kindness, whether with a friend, your family, or just by yourself … It can be for a friend, family or strangers. It can be a fun activity to come up with these kind acts, and if you need help, there’s plenty on the internet. Some of our favorites are taping lottery tickets to car windows, giving a bouquet of flowers to a stranger, putting extra change into parking meters, paying for the coffee of the person behind you, et cetera.” — Carly Long Put in some time “Volunteer with your loved one. The opportunities are endless depending on your interests. Look into volunteer opportunities at your local children’s hospital, hospice,… ASPCA, food bank, homeless shelter, et cetera. You can even volunteer to watch your friend or family’s children so the adults can have a fun night out.” — Carly Long Consider where it came from “If you really want to give a physical new gift, consider products that help reduce waste, like a metal straw, cloth napkins, beeswax cloth food wraps, metal water bottle, travel mug or reusable grocery bag. Or give a gift certificate to their favorite store. That way they can get exactly the thing they want or need.” — Aran Galligan, designer of eco-friendly jewelry line Aide-mémoire Jewelry Lose (or re-use) the wrapping paper If you do want to give a physical gift, think twice about how you’re presenting it. A lot of holiday waste comes from wrapping and packaging that’s used only once and thrown away. “Most mass-produced wrapping paper can’t be recycled due to the shiny
pile-cc
7/40 Four letters picked without replacement from {u: 4, k: 7, o: 1, g: 6, m: 2}. What is prob of picking 2 m, 1 k, and 1 g? 14/1615 Three letters picked without replacement from zlzzzllllzzzz. What is prob of picking 3 l? 5/143 Three letters picked without replacement from {w: 1, x: 17, b: 1}. Give prob of picking 1 b and 2 x. 8/57 What is prob of picking 3 m and 1 a when four letters picked without replacement from {m: 3, a: 4, u: 4, t: 3, p: 6}? 4/4845 Calculate prob of picking 2 w when two letters picked without replacement from wawwwwwwawaw. 6/11 Three letters picked without replacement from {y: 6, l: 4}. What is prob of picking 1 l and 2 y? 1/2 What is prob of picking 2 s and 1 p when three letters picked without replacement from {c: 3, o: 3, s: 9, p: 2}? 9/85 Three letters picked without replacement from wawwaaawwawaawaawawa. Give prob of picking 3 a. 11/76 Two letters picked without replacement from {b: 2, d: 1, k: 2}. What is prob of picking 2 k? 1/10 Two letters picked without replacement from {t: 4, z: 2, d: 1, o: 3, h: 4, w: 6}. Give prob of picking 2 o. 3/190 Calculate prob of picking 1 f, 1 g, and 2 y when four letters picked without replacement from {c: 2, y: 2, m: 3, g: 9, f: 1, p: 1}. 1/340 Two letters picked without replacement from sidzdddddsdddeddzd. What is prob of picking 1 i and 1 z? 2/153 What is prob of picking 2 z when two letters picked without replacement from zzzz? 1 What is prob of picking 1 u and 1 g when two letters picked without replacement from {u: 1, v: 1, a: 1, n: 3, k: 8, g: 2}? 1/60 Three letters picked without replacement from
dm_mathematics
Get you picks in. Also please note Larry Bevans will be receiving the picks next week, I will be out of town. Larry's e-mail address is [email protected]. Don't forget if you don't send something to me you are out of the pool. Bob ****************************************************************** This email and any files transmitted with it from the ElPaso Corporation are confidential and intended
enron_emails
Although the Board of Adjustment application contained a description of the property, stated that JV Road, L.P. was “seller[] to” SDN, Ltd., and was signed by Mike Young, the agreement was not an agreement between the parties and was not made for the purpose of memorializing an agreement to sell the real property at issue. It was an application in which Young represented himself as the seller—or potential seller—and in which he authorized Lopez-Phelps to act as his agent, but did not show that a sale had been made or that a contract had been signed. Moreover, the application contained none of the material terms, including the price for which the property would be sold. The application represented Young’s attempt to secure rezoning with the City, which was a prerequisite to a sale between Young and DeNucci. The application was not an agreement to make a sale of real property. DeNucci also relies on a series of email correspondence between the parties that, he alleges, demonstrates in writing that he and Young had agreed to all material terms. Specifically, he refers to a July 7, 2006 email in which he sets out the status of his negotiations with Henges and his thoughts about incorporating the Henges tract. He continues by proposing to proceed with the project without the Henges tract. DeNucci then writes: “There are some issues we would need to make sure we all agree on.” He then sets out a list of five items yet to be agreed upon, including the number of parking spaces available for Chuy’s, the price, the timing, the possibility of a 7 temporary parking lot, and other miscellaneous issues, including an issue with an easement and sewer service. On the same day, in response to this email, Young wrote: We jointly developed the property with Joe’s and have a reciprocal parking agreement that, I believe, will allow us to use it as we see fit. We will need to have Ann look at the joint use agreement (Hatcher will you get this from Sharon and to Ann v?). As for the other stuff...it makes more sense to get henges on the plate... I believe it is good for you to talk to his at
freelaw
strings are the reason I regret not adopting rust back when as a user of a pre-1.0 language I could have joined in efforts to lobby against this insanity. \--- As a sidenote, string_view is so late in coming to the c++ world that it's not even funny. Having a separate std::string with an "implementation-defined" in- memory representation in a world of c strings (char *) is inane beyond belief. (Yes, nulls in strings would still be a problem. But why do your strings have nulls in the first place? That data should probably be a vector of strings or a [vector|array] of uint8_t (even if just typedef'd to unsigned char) and C++ strings should have been mandated utf8, contiguous, and null-terminated. You should be able to compose a zero-copy, read-only, non-owned string from a character array and decompose automatically to it. And don't get me started on the fact that C++ doesn't have sprintf because of the obsession with sticking to the overly verbose and way too complicated streaming operators. Developers end up using c strings with sprintf to format text and then copy it back to a std::string just to work around that stupidity. ~~~ weirdwitch Anything implemented for &str is automatically implemented for String, because String implements Deref<Target=str>. Most useful "String" methods are actually &str methods that you get access to through that deref trait. Dereferencing a String doesn't return a raw pointer, I'm not sure where you got that idea. ~~~ ComputerGuru Yes, anything implemented for &str is automatically implemented for String... except some API are stupidly implemented for &string instead. And you can't pattern match strings properly (think some `for in`) without first explicitly converting to &str. Dereferencing a string does not return a raw pointer, that was exaggeration on my behalf. But a string is a container, so *string returns.... &str? But string.deref() returns str? Don't get me wrong, I'm fully invested in the language [0], [1], [2], but it's got a lot of warts that could have been avoided by
hackernews
This research plan is directed towards improving artificial kidney technology, one of the specific areas of interest to the National Institute of Arthritis, Diabetes and Digestive and Kidney Diseases. By the middle of 1977 more than 36,000 patients were being regularly treated for uremia by hemodialysis at an annual cost of $650,000,000. Generally, this treatment required the use of large complicated machines at treatment centers. Sorbent regeneration of dialysate is one approach to substantially reducing the cost
nih_exporter
The aim of this study was to elucidate perimenopausal bone loss in relation to menstrual conditions and to investigate the long-term effect of menopause on bone loss in aged women. The rate of change in bone mineral density (BMD) was measured twice at an exact interval of 12 months by dual-energy X-ray absorptiometry (DXA) at the lumbar spine in 176 pre- and postmenopausal healthy women 41-65 years of age. Serum follicle-stimulating hormone
pubmed_abstracts
Allelic frequencies were estimated by direct counting. Gene diversity and haplotype diversity were calculated according to Nei \[[@CR16]\]. Comparisons among populations were computed by an analysis of molecular variance (AMOVA) test. Pairwise values of *Φ*~st~, an analogue of *F*~st~ that takes the evolutionary distance between individual haplotypes into account \[[@CR17], [@CR18]\], were calculated to measure genetic distances between minimal 9-locus haplotypes of the Paiwan and the published data from ten other populations \[[@CR19]--[@CR27]\] from the region (*n* = 2112) with the statistical significance determined by a permutation test (10,000 replicates). We used an implementation of AMOVA provided at the YHRD website \[[@CR28]\]. The DYS389I allele length was obtained by subtracting the shorter allele from the longer allele at DYS389I/II. To illustrate the relationship between populations based on pairwise *Φ*~st,~ an MDS plot was created by using the "Population analysis" tools of the YHRD \[[@CR28]\]. A median-joining network \[[@CR29]\] based on 12-locus Y-STR haplotypes (omitting the complex repeats) was calculated using the NETWORK 2.0b software (available online, [www.fluxus-engineering.come/sharenet.htm](http://www.fluxus-engineering.come/sharenet.htm)). Results and discussion {#Sec3} ====================== The Y-STR allele frequencies of the Paiwan population are shown in Table S[1](#MOESM1){ref-type=""}. Forensic indices such as the locus diversity and haplotype diversity values were calculated from the allelic frequency for each locus. Of the 17 markers analyzed, DYS385ab showed the greatest degree of diversity, 0.8354, and DYS438 showed the lowest, 0.1014. A total of 135 haplotypes were identified in the 208 individuals studied, of which 102 were unique (Table S[2](#MOESM2){ref-type=""}). The overall observed haplotype diversity reached 0.9922 ± 0.0010, and the discrimination capacity was 0.6490. The most frequent 17-locus haplotype was H122 that was identified in nine individuals (Table S[2](#MOESM2){ref-type=""}). The diversity values were markedly reduced when compared to the major population in Taiwan \[[@CR30]\]. In addition, three intermediate or duplicated alleles at
pubmed_central
// Constructor public ConsumerClass() { // Initialize all the mappings for all the required types for this consumer class here. // This is a one time overhead, but will definitely speedup the methods within this class // You could move this part further up the hierarchy of inheritance, to avoid repetitions in every other consumer class. // For int InitMap.Add(typeof(int), data => InitWith(data, -1)); DoSomethingAMap.Add(typeof(int), DoSomethingA<int>); DoSomethingBMap.Add(typeof(int), DoSomethingB<int>); // For double InitMap.Add(typeof(double), data => InitWith(data, -9.99d)); DoSomethingAMap.Add(typeof(double), DoSomethingA<double>); DoSomethingBMap.Add(typeof(double), DoSomethingB<double>); // other types, if needed by this consumer } void InitValues(DataClass data) { // This takes care of your if s InitMap[data.ValueType].Invoke(data); } void InitWith<T>(DataClass data, T defaultValue) { // much faster var array = (T[])data.GetValues(); for (var i = 0; i < array.Length; i++) array[i] = defaultValue; } void DoSomethingA(DataClass data) { DoSomethingAMap[data.ValueType].Invoke(data); } void DoSomethingA<T>(DataClass data) { var array = (T[])data.GetValues(); // do something } void DoSomethingB(DataClass data) { DoSomethingBMap[data.ValueType].Invoke(data); } void DoSomethingB<T>(DataClass data) { var array = (T[])data.GetValues(); // do something } } There is some redundant code in the constructor, so there could still be a better way to write this mechanism. But you should get an idea of how you could clean up your ifs
stackexchange
prescription eyeglass lenses are curved in such a way that light is correctly focused onto the retina of a patient's eye, improving vision. Such lenses are formed from glass or plastic lens “blanks” having certain desired properties to provide the correct prescription for the patient. The blanks are usually circular and of substantially larger dimension, for example 70 mm in diameter and 10 mm thick, compared to the relatively smaller finished lenses assembled into eyeglass frames. Therefore, a lens blank must be edged to fit an eyeglass frame selected by the patient. Ophthalmic laboratory technicians cut, grind, edge, and polish blanks according to prescriptions provided by dispensing opticians, optometrists, or ophthalmologists. In addition, the large diameter blank is sized and shaped to fit into the frame selected by the patient. The lens blank may be shaped using an edger, such as the lens edger disclosed in U.S. Pat. No. 6,203,409 to Kennedy et al., the disclosure of which is incorporated herein by reference. The blank is edged so that the periphery of the finished lens fits the frame. As known in the art, edging of a lens blank typically requires the application of a block to a surface thereof. The block is releasably secured to a clamp assembly, so that rotation of the clamp assembly causes corresponding rotation of the lens blank. The periphery of the blank is cut to the desired size using a router tool. The periphery may also be polished using a polishing tool. A bevel is often formed about the periphery of the lens, particularly adjacent the wearer. A combination tool incorporating a router and polishing hub may be used, as disclosed in the '409 patent. The finished lens may then be assembled with the selected eyeglass frames. The frames include two spaced openings in which the finished lenses are mounted. The frame openings frequently have a bevel or a tongue, which interlocks with a complementarily shaped bevel or groove, respectively, formed about the peripheral edge of the lens. The interlock between the complementary bevel and groove helps to secure the lens within the opening of the frames. The router and polishing tools on the edger form the bevel or groove about the lens. The configuration of the bevel or groove that is edged into the peripheral edge of the lens may vary depending on the configuration of the bevel or tongue in the frame openings. Therefore, various router and polishing tools are provided for forming different bevel or groove configurations
uspto_backgrounds
Nicole Aish (maiden name Jefferson, born March 8, 1976) is a long distance runner who is a U.S. National Championship Marathon winner and a bronze medalist at the 2003 Pan American Games in the 5,000 metres. Running career Since she was cut from her high school basketball team, Aish decided to become a runner. She ran cross country and track at Western Colorado Mountaineers with Elva Dryer. Aish set multiple school records on her way to becoming the national champion at the 1998 and 1999 NCAA Division II Women's Outdoor Track and Field Championships in the 3,000 metres. She finished her college career also as the one mile national champion in the 1999 NCAA Division II Women's Indoor Track and Field Championships. She still holds the school record for fastest time in the mile (4:38.76). Aish continued running after college. In 2001 she raced 3,000 metres at the Prefontaine Classic, where she placed 13th. Two years later, she ran a 32:10 in the 10,000 metres, qualifying for the 2004 U.S. Olympic Track Trials. Aish continued racing track and road races around the country. Her first ever half-marathon was in the Monterey Peninsula of California, which she won. Aish then netted prize money for win a large 10k in Colorado. A year later, in 2005, she also won her first-ever marathon, the Twin Cities Marathon. She finished with a time of 2:40.21, which happened to be the slowest winning time, likely due to the heat—the temperature at the starting line was more than 70 degrees F. Although her hamstrings cramped and she walked briefly, Aish won with a comfortable lead. She won $30,000 and the title of U.S. National Marathon Champion. Later in 2006, Aish had hip surgery, which stopped her from running in any more major races. She still competes in shorter distance races, such as the FireKraker 5k for the 4th of July in her hometown in Colorado. She has won nearly $85,000 in her running career so far. Early and personal life Aish is married to Michael Aish, a long distance runner who competed for the 2000 and 2004 New Zealand Olympic Team. They ran together and won respective men's and woman's titles in the Monterey Half Marathon. Aish started a blog about her personal and
wikipedia_en
Acknowledgment ============== The authors are grateful to Dr. Ram Kossowsky supporting the presentation of the work at the NATO ARW. This work was partly supported by the National Foundation “Scientific Research” under Grant 421.  [99]{} R. Simon and P. M. Chaikin, Phys. Rev. B, [**23**]{} (9) (1981) 4463. M. A. M. Gijs, D. Scholten, Th van Rooy and A. M. Gerrits Phys. Rev. B, [**41**]{} (16), (1990) 11627. G.Deutscher, R.W.Simon , J. Appl. Phys., [**69**]{} (7), (1991) 4137. H. Z. Durusoy, D. Lew, L. Lombardo, A. Kapitulnik, T. H. Geball, M. R. Beasley, Physica C 226, N3-4 (1996) 253 G. Lubberts, J. Appl. Phys., [**68**]{} (2), (1990) 688. R. Pinto, P. R. Apte and S. P. Pai, Physica C [**207**]{} (1993) 13 J. Jung, M. A-K Mohamed and J. P. Franck, Supercond. Sci Technol., [**4**]{} (1991) S217. E. Nazarova, M. Kostova, A. Zahariev and I. Iordanov, Cond. Matt. and Mater. Comm., [**2**]{} (1995) 31. J. H. Claassen, Magnetic Susceptibility of Superconductors and Other Spin Systems, ed. by R.A.Hein et al., Plenum Press, NY, 1991 pp 405-422 T. Wada, N. Susuki, A. Maeda, T. Yabe, K. Uchinokura, S. Uchida, S. Tanaka, Phys. Rev. B, [**39**]{} (1989) 9126. Y. Song, J. Golben, S. Chittipedi and R. Gaines, Phys. Rev. B, [**28**]{} (1988) 4605. J. P. Singh, H. J. Leu, R. B. Poeppel, E. Van Voortees, G. T. G
arxiv
[Fact] public async Task TestTwoElementsAsync() { var testCode = @"public delegate void Foo(); public delegate void Bar(); "; var fixedCode = new[] { ("/0/Test0.cs", @"public delegate void Foo(); "), ("Bar.cs", @"public delegate void Bar(); "), }; DiagnosticResult expected = Diagnostic().WithLocation(2, 22); await VerifyCSharpFixAsync(testCode, this.GetSettings(), expected, fixedCode, CancellationToken.None).ConfigureAwait(false); } [Fact] public async Task TestTwoGenericElementsAsync() { var testCode = @"public delegate void Foo(); public delegate void Bar<T1, T2, T3>(T1 x, T2 y, T3 z); "; var fixedCode = new[] { ("/0/Test0.cs", @"public delegate void Foo(); "), ("Bar.cs", @"public delegate void Bar<T1, T2, T3>(T1 x, T2 y, T3 z); "), }; DiagnosticResult expected = Diagnostic().WithLocation(2, 22); await VerifyCSharpFixAsync(testCode, this.GetSettings(), expected, fixedCode, CancellationToken.None).ConfigureAwait(false); } [Fact] public async Task TestTwoElementsWithRuleDisabledAsync() { this.SettingsConfiguration = SA1402SettingsConfiguration.ConfigureAsNonTopLevelType; var testCode = @"public delegate void Foo(); public delegate void Bar(); "; await VerifyCSharpDiagnosticAsync(testCode, this.GetSettings(), DiagnosticResult.EmptyDiagnosticResults, CancellationToken.None).ConfigureAwait(false); } [Fact] public async Task TestTwoElementsWithDefaultRuleConfigurationAsync() { this.SettingsConfiguration = SA1402SettingsConfiguration.KeepDefaultConfiguration; var testCode = @"public delegate void Foo(); public delegate void Bar(); "; await VerifyCSharpDiagnosticAsync(testCode, this.GetSettings(),
github
1 5 3 1 1 .600 Andrew Morrissey H.G. Hadden 1895 1895 1 4 3 1 0 .750 Andrew Morrissey Frank E. Hering 1896 1898 3 19 12 6 1 .632 Andrew Morrissey James McWeeney 1899 1899 1 10 6 3 1 .600 Andrew Morrissey Pat O'Dea 1900 1901 2 20 14 4 2 .700 Andrew Morrissey James F. Faragher 1902 1903 2 18 14 2 2 .778 Andrew Morrissey Red Salmon 1904 1904 1 8 5 3 0 .625 Andrew Morrissey Henry J. McGlew 1905 1905 1 9 5 4 0 .556 Andrew Morrissey Thomas A. Barry 1906 1907 2 14 12 1 1 .857 Andrew Morrissey Victor M. Place 1908 1908 1 9 8 1 0 .889 John W Cavanaugh Shorty Longman 1909 1910 2 14 11 1 2 .786 John W Cavanaugh Jack Marks 1911 1912 2 15 13 0 2 .867 John W Cavanaugh Jesse C. Harper 1913 1917 5 40 34 5 1 .850 John W Cavanaugh Knute Rockne 1918 1930 13 122 105 12
pile-cc
4 What is the tens digit of 4393? 9 What is the units digit of 25656? 6 What is the units digit of 117500? 0 What is the ten thousands digit of 10667? 1 What is the tens digit of 98269? 6 What is the tens digit of 1539? 3 What is the thousands digit of 80716? 0 What is the tens digit of 22078? 7 What is the thousands digit of 2236? 2 What is the ten thousands digit of 82222? 8 What is the tens digit of 21413? 1 What is the units digit of 9541? 1 What is the ten thousands digit of 41556? 4 What is the thousands digit of 14603? 4 What is the tens digit of 3239? 3 What is the thousands digit of 20007? 0 What is the tens digit of 48587? 8 What is the units digit of 747? 7 What is the tens digit of 40537? 3 What is the hundreds digit of 27079? 0 What is the thousands digit of 19870? 9 What is the units digit of 4200? 0 What is the hundreds digit of 16778? 7 What is the tens digit of 921? 2 What is the hundreds digit of 171478? 4 What is the units digit of 945? 5 What is the tens digit of 2573? 7 What is the units digit of 1250? 0 What is the thousands digit of 4031? 4 What is the units digit of 5391? 1 What is the units digit of 20982? 2 What is the tens digit of 1911? 1 What is the units digit of 9259? 9 What is the hundreds digit of 6607? 6 What is the hundreds digit of 27114? 1 What is the units digit of 51696? 6 What is the ten thousands digit of 40361? 4 What is the units digit of 3600? 0 What is the tens digit of 3451? 5 What is the hundreds digit of 1658? 6 What is the units digit of 2073? 3 What is the thousands digit of 5089? 5 What
dm_mathematics
Body Shop Members: On Saturday, June 10th, portions of the Body Shop will be closed for approximately 90 days to build the pillar supports for the Enron Center Sky Bridge. This construction will necessitate the closure/relocation of Studio B, the free weight area and massage therapy services. Many of the Yoga, Tai Chi, and Abs Lab classes previously held in Studio B will be moved to Studio A. Because of space constraints
enron_emails
In particular, he opined that the subject property experienced 60-mph winds because Miami-Opa Locka Airport, which is located more than three miles from the subject property, recorded wind “gusts” of 60 miles per hour of unknown duration on June 29, 2013. Significantly, the claimed date of loss was two weeks later on or about July 17, 2013. Moreover, Mr. Brizuela admitted “Predicting wind at other locations, wind speed from a particular direction at a particular time, with an acceptable degree of accuracy is currently highly inaccurate.” Analysis This Court reviews a trial court’s ruling on a motion for summary judgment de novo. Volusia Cty. v. Aberdeen at Ormond Beach, L.P., 760 So. 2d 126, 130 (Fla. 2000). “Summary judgment is proper if there is no genuine issue of material fact and if the moving party is entitled to a judgment as a matter of law.” Id. “Summary judgment is designed to test the sufficiency of the evidence to determine if there is sufficient evidence at issue to justify a trial or formal hearing on the issues raised in the pleadings.” The Fla. Bar v. Greene, 926 So. 2d 1195, 1200 (Fla. 2006). Because summary judgment tests the sufficiency of the evidence 2Although he expressly states the roof was replaced (“the roof was replaced before we inspected”), he also states “[w]e would recommend the replacement of the roofing system if the homeowner has not done it yet.” 5 to justify a trial, it “is proper only if, taking the evidence and inferences in the light most favorable to the non-moving party, and assuming the jury would resolve all such factual disputes and inferences favorably to the non-moving party, the non- moving party still could not prevail at trial as a matter of law.” Moradiellos v. Gerelco Traffic Controls, Inc., 176 So. 3d 329, 334–35 (Fla. 3d DCA 2015). A court considering summary judgment must avoid two extremes. On the one hand, “a motion for summary judgment is not a trial by affidavit or deposition. Summary judgment is not intended to weigh and resolve genuine issues of material
freelaw
The people who were used to Js couldn't just write everything they would Js as this article describes, but what they couldn't write seemed to be stuff that would break a lot of compile time checks. It was a little battle to get one guy to stop using <any> everywhere, but 9/10 times that he came to me with a broken script, it was something that satisfying the compiler without <any> would have found the issue. And the Java side now looks so much cleaner because we have a compiler that can check that we're sending it the right types, so there isn't as much work trying to cast everything from Object to different representations it could have in Js. I define interfaces that the Java side implements with 'declare' and get that type checking and autocomplete for exploring the API for free, which is another huge win. I've noticed a lot of JVM-Js integration (Kotlin has Js interop iirc) and I think Typescript is really great there. Flow looked interesting, but it felt like its approach is more targeted towards existing code bases trying to migrate to it, and we didn't have that constraint ------ Eridrus I think this is a less relevant issue now that tsc can include plain .js files in builds. I think the spirit of being very close to JavaScript and being easily convertible from one to the other is more important than being a strict superset. ------ k__ Polymorphism of JavaScript functions is a bit of a pain point in TypeScript, I think. I often got some query methods, that deliver different types of objects, which share a parent class. Like GameObject, Player, Enemy. const player = getGameObject('playerId') Now player will be typed like the return type of getGameObject. If I now try to set an attribute, specific to `Player`, it will fail: player.mousePosition = [1, 2] // won't work, because GameObject doesn't have a mousePosition Also, setting the type of player to Player, will fail too: const player : Player = getGameObject('playerId') // getGameObject could return an Enemy
hackernews
Project summary/abstract This proposal is to synthesize and commercialize Fmoc protected glycoamino acids (GAAs) in large scale. Glycoproteins have been reported to exhibit a pivotal role in processes as diverse as fertilization, neuronal development, hormone activities, immune surveillance, and inflammatory responses. GAAs are the brick to build all glycopeptides and glycoproteins. The synthesis of GAAs requires sophisticated protection/deprotection and activation strategies that is time consuming. Glycoscientists have faced
nih_exporter
A few studies have shown more central auditory processing deficits in children with attention-deficit/hyperactivity disorder (ADHD) than in nondisabled children. Because these studies failed to screen participants with ADHD for learning disabilities (LD), it is not clear whether these deficits are correlates of ADHD or LD or both. In the present study, the central auditory processing ability of children with ADHD, ADHD with LD, and no disabilities was examined. Results indicated lower central auditory processing ability, and significant correlations between
pubmed_abstracts
QUESTIONS {#S2} ========= 1. **What are the histopathologic characteristics of nodular hidradenoma?** 2. **How does nodular hidradenoma present clinically?** 3. **What are competing differential diagnoses of nodular hidradenoma?** 4. **What is the management of nodular hidradenoma?** DISCUSSION {#S3} ========== In 1990, Abenoza and Ackerman introduced the poroid hidradenoma (PH) as the fourth subtype of poroma. They described it as a rare, benign adnexal tumor with morphologic characteristics of both a poroma, with poroid and cuticular cells, and a hidradenoma, with both solid and cystic components confined solely within the dermis.[@B1] Recently, it has been proposed to reclassify PH as a subtype of nodular hidradenoma by subdividing nodular hidradenoma into those with eccrine differentiation (PH) and those with apocrine differentiation (clear cell hidradenoma \[CCH\]).[@B2] The pathology of nodular hidradenoma generally shows unencapsulated, eosinophilic, polygonal or fusiform cells often with sclerotic stroma, cystic spaces, and some cellular differentiation.[@B3] In our patient, the pathology was atypical, with the typical features of both poroid and clear cell hidradenoma, in addition to cellular atypia and increased mitotic figures. The clinical presentation of PH and CCH is similar. It characteristically presents as a solitary, smooth, well circumscribed, reddish to blue papule or nodule of up to a few cm in diameter.[@B4] However, sizes up to 30 cm × 20 cm have been reported in literature. Patients may be asymptomatic or may present with growth, pain, or bleeding.[@B5] They generally occur on the head and neck, with very rare cases on the trunk and extremities. There is a slight female predilection and age of onset is generally more than 40, though reports range from 3 to 93.[@B6] Our patient was a 26-year-old woman, who presented with a growing 2-cm nodule of normal skin color on the medial aspect of the third left toe. To our knowledge, this is the first case of benign nodular hidradenoma ever to be reported in this location. Because of the nond
pubmed_central
I'm having a hard time figuring out how to put this all together. I have a puzzle solving app on the mac. You enter the puzzle, press a button, and while it's trying to find the number of solutions, min moves and such I would like to keep the UI updated. Then once it's finished calculating, re-enable the button and change the title. Below is some sample code from the button selector, and the solving function: ( Please keep in mind I copy/paste from Xcode so there might be some missing {} or some other typos.. but it should give you an idea what I'm trying to do. Basicly, user presses a button, that button is ENABLED=NO, Function called to calculate puzzle. While it's calculating, keep the UI Labels updated with moves/solution data. Then once it's finished calculating the puzzle, Button is ENABLED=YES; Called when button is pressed: - (void) solvePuzzle:(id)sender{ solveButton.enabled = NO; solveButton.title = @"Working . . . ."; // I've tried using this as a Background thread, but I can't get the code to waitTilDone before continuing and changing the button state. [self performSelectorInBackground:@selector(createTreeFromNode:) withObject:rootNode]; // I've tried to use GCD but similar issue and can't get UI updated. //dispatch_queue_t queue = dispatch_queue_create("com.gamesbychris.createTree", 0); //dispatch_sync(queue, ^{[self createTreeFromNode:rootNode];}); } // Need to wait here until createTreeFromNode is finished. solveButton.enabled=YES; if (numSolutions == 0) { solveButton.title = @"Not Solvable"; } else { solveButton.title = @"Solve Puzzle"; } } Needs to run in background so UI can be updated: -(void)createTreeFromNode:(TreeNode *)node { // Tried using GCD dispatch_queue_t main_queue = dispatch_get_main_queue(); ...Create Tree Node and find Children Code...
stackexchange
The invention relates generally to coke oven batteries. Of particular interest to the invention is an arrangement for changing the heat supply to the ovens of a coke oven battery from a condition of extreme heating, that is, a condition in which large quantities of heat are supplied to the ovens, to a condition of lesser or no heating, that is, a condition in which smaller quantities of heat are supplied to the ovens or in which no heat is supplied to the ovens, as well as for changing the heat supply in the opposite sense. An arrangement for changing the heat supply to the ovens of a coke oven battery is known and includes a control linkage which extends around the battery. This control linkage is operative for changing the flow of air and hot waste gases, as well as for regulating the supply of combustion air, via air inlet valves and waste gas throttle valves which may be in the form of butterfly valves. The arraangement includes a further control linkage which operates a three-way valve provided for the decarbonizing air. The reason that it is desirable to be able to change the heat supply to the ovens of a coke oven battery is based on the finding that savings of up to 10 percent in heating costs may be realized when, instead of providing a constant heat supply for the ovens as has been the conventional practice, the heat supply is adjusted to the state of coking of the charge by so-called programmed heating. Such adjustment of the heat supply consists in that coking of the coal is carried out using a large heat supply at the beginning of the coking operation with the heat supply being reduced towards the end of the coking operation. The regulation of the heat supply may be effected by means of a control program which operates via fuel gas and air valves, as well as waste gas valves and throttling flaps, provided for each heating wall of the coke oven battery. This control program requires relatively large expenditures for the measuring and regulating mechanisms which are necessary. With respect to the savings in heating costs, it is especially significant that an effective heating program need not provide particularly fine control over the heat supply during the entire duration of the coking period. The reason resides in that the thermal response of an oven system is generally quite sluggish. In fact, it has been found to be adequate when phases of extreme heating alternate with phases of no heat supply whatsoever. Here, the periods for which the heat supply is interrupted become longer as the coking operation progresses. Although the known
uspto_backgrounds
David Voas David Voas (born 1955) is a quantitative social scientist. He is currently Professor of Social Science and Head of the Department of Social Science at the UCL Institute of Education. He was previously Professor of Population Studies at the University of Essex and Simon Professor of Population Studies at the University of Manchester. Voas is on the executive committee of the European Values Study and is co-director of British Religion in Numbers, an online centre for British data on religion. He serves on the council of the International Society for the Sociology of Religion and on the editorial boards of the British Journal of Sociology and the Journal for the Scientific Study of Religion. His research concerns religious change and value change in modern societies, the intergenerational transmission of religion and values, and attitudes of and towards ethno-religious minorities. Early life David Voas was born in the United States. His father is Robert B. Voas, a psychologist who had a key role in selecting and training the first group of NASA astronauts and in recent decades has been a leader in policy research on alcohol and highway safety. David Voas left the US at the age of 15 to attend Atlantic College, an international school in South Wales. He subsequently received bachelor's and master's degrees from London School of Economics and a PhD from Cambridge. Career Voas worked in the private sector for a number of years and also spent extended periods outside the UK, particularly in France, the United States, and Bulgaria. Academic career He returned to academic life in 1998, first as a researcher at the University of Liverpool and subsequently as a lecturer at the University of Sheffield. He was awarded a Simon Research Fellowship at the University of Manchester in 2003 and remained there for eight years, first in the Cathie Marsh Centre for Census and Survey Research and later in the Institute for Social Change. In 2007, he was promoted to professor and given a chair in the Institute for Social Change, later merged into the Cathie Marsh Institute for Social Research. Voas was Professor of Population Studies in the Institute for Social and Economic Research at the University of Essex from November 2011 to January 2016. He took up his present position at UCL in February 2016. References Category:Living people Category:British sociologists Category:Alumni of the London School of Economics Category:Alumni of the University of Cambridge Category:Academics of the University of Manchester Category:1955
wikipedia_en
We now find that, in order to improve the rigidity statement of Theorem 2.1, the optimal parameters $p, q,$ are $$p = - \frac{1}{2} , \quad q = 1 .$$ For this choice of parameters, the equation (3.4) gives $$\begin{aligned} & & (\varphi, \varphi)^2 ( \overline{\nabla} \, \overline{\varphi_p}, \, \overline{\nabla} \, \overline{\varphi_p} ) \\ & & \\ & = & ( \nabla \varphi, \nabla \varphi) + \frac{1}{2} (\varphi, \varphi)^{-1} ( D \varphi, {\rm grad} (\varphi, \varphi) \cdot \varphi ) - \frac{3}{8} (\varphi, \varphi)^{-1} \vert {\rm grad} (\varphi, \varphi) \vert^2 .\end{aligned}$$ Applying the Schrödinger-Lichnerowicz formula $$\triangle(\varphi, \varphi) = -2 ( \nabla \varphi, \nabla \varphi ) +2 ( D^2 \varphi, \varphi ) - \frac{1}{2} S_g (\varphi, \varphi) ,$$ where $\triangle = - {\rm div} \circ {\rm grad}$, one proves the following lemma. For the choice (3.7) of parameters, we have $$\begin{aligned} & & \frac{1}{2} {\rm div} \{ (\varphi, \varphi)^r {\rm grad} (\varphi, \varphi) \} \\ & & \\ & = & (\varphi, \varphi)^r \Big\{ (\varphi, \varphi)^2 ( \overline{\nabla} \, \overline{\varphi_p}, \, \overline{\nabla} \, \overline{\varphi_p} ) + \frac{1}{4} S_g (\varphi, \varphi) - ( D^2 \varphi, \varphi ) - \frac{1}{2} (\varphi, \varphi)^{-1} ( D \varphi, {\rm grad} (\varphi, \varphi)
arxiv
# OPTIONS **--help** Print usage statement **--config**="" Specifies the location of the Docker client configuration files. The default is '~/.docker'. **-D**, **--debug**=*true*|*false* Enable debug mode. Default is false. **-H**, **--host**=[*unix:///var/run/docker.sock*]: tcp://[host]:[port][path] to bind or unix://[/path/to/socket] to use. The socket(s) to bind to in daemon mode specified using one or more tcp://host:port/path, unix:///path/to/socket, fd://* or fd://socketfd. If the tcp port is not specified, then it will default to either `2375` when `--tls` is off, or `2376` when `--tls` is on, or `--tlsverify` is specified. **-l**, **--log-level**="*debug*|*info*|*warn*|*error*|*fatal*" Set the logging level. Default is `info`. **--tls**=*true*|*false* Use TLS; implied by --tlsverify. Default is false. **--tlscacert**=*~/.docker/ca.pem* Trust certs signed only by this CA. **--tlscert**=*~/.docker/cert.pem* Path to TLS certificate file. **--tlskey**=*~/.docker/key.pem* Path to TLS key file. **--tlsverify**=*true*|*false* Use TLS and verify the remote (daemon: verify client, client: verify daemon). Default is false. **-v**, **--version**=*true*|*false* Print version information and quit. Default is false. # COMMANDS Use "docker help" or "docker --help" to get an overview of available commands. # EXAMPLES For specific client examples please see the man page for the specific Docker command. For example: man docker-run # HISTORY
github
A chemical reaction happens when cannabis is heated. During this reaction, the amount of THC in a product can actually increase based on the strength of the plant. THC and total THC are both listed on the packaging of every product. Look at the total THC to know the maximum amount of THC you may ingest when you use cannabis. This higher THC percentage will give you the best idea of how cannabis will affect you. Ways to Use Cannabis What are cannabis oils? Cannabis oils are extractions of THC and/or CBD from the cannabis plant that are in carrier oils like olive, grapeseed or coconut oils. Cannabis oils will be available for sale in licensed cannabis stores. Cannabis oils can be used by placing droplets under the tongue or by infusing into edibles. Unlike dried cannabis, the THC and CBD contents of cannabis oils are listed in mg/ml instead of a percentage. You’ll see ranges of less than 1 mg/ml up to 30 mg/ml. Like dried cannabis, it’s always best to start with a lower level of THC and an equal or higher level of CBD. If you’re using cannabis oils, check to make sure you’re not allergic to the ingredients, as they may contain peanuts, soy or other allergens. What are edibles? Cannabis edibles are products infused with THC, the intoxicating compound from the cannabis plant. Edibles could also be infused with CBD. THC and CBD can be added into edible products like brownies, muffins, candies, juice, etc. Edibles will not be available for retail sale on October 17, 2018, but legal users can make their own. Consuming edibles is safer for your lungs than smoking or vaping cannabis, but it can take much longer (up to 2 hours) before you feel the effects, which increases the risk of overdose. If you’re making edibles, estimate the amount of THC in milligrams and portion out serving sizes of less than 3 mg to 5 mg, especially if you’re new to cannabis. Start with one serving and wait at least 90 minutes before you consume more, so that your body can metabolize the edible and you feel the effects. Buying Cannabis Where can I buy legal cannabis? In Manitoba, you can only buy legal cannabis from a cannabis retailer
pile-cc
5 What is 9 - (-8 + (6 - (-18 + 5)) - -6)? -8 What is 13 + -23 - (-8 + -4 - 4)? 6 What is the value of 12 - 7 - (0 + -9 - 12)? 26 What is 4 + ((-4 - -1) + (-1 - -6) - 5)? 1 Calculate 5 + (-7 - (2 - -7 - 10)) + -27. -28 What is -27 - (14 + -13 - 19)? -9 -10 - (3 + (-19 + 6 - 6) + 12) -6 What is -8 + (10 - (4 + -5)) - (-3 + -2)? 8 Evaluate -19 - -11 - (-2 - 1). -5 Calculate -3 + -6 + 7 + (-8 - (5 - 4)). -11 Evaluate 8 + (-26 - -22) + -2 + 1. 3 Calculate -19 + (13 - 22 - -15). -13 What is the value of (6 - (24 + -7 + -7)) + (-4 - 1)? -9 40 - (16 - (12 + -16)) 20 What is the value of 0 + 3 - ((7 - 6 - 6) + 1)? 7 What is the value of 4832 + -4834 + (-1 - -1 - 15)? -17 15 - (8 - 3 - (5 + -1)) 14 What is -12 + 6 + -3 - -14? 5 Evaluate 12 + (-30 - (-13 + 3)). -8 Evaluate 4 - (0 - (5 + (-6 - 1) - -1)). 3 -1 + 18 + -2 - 4 11 What is the value of 2 - ((10 - 22) + 28)? -14 Calculate 10 + (4 - (3 + -6 + 8 + -2)). 11 Evaluate -3 + (-1 - (6 + -6)) + -6. -10 Evaluate 7 - (4 - (-6 + -1)). -4 What is -138 + 151 + -9 + -8? -4 What is 10 + -4 + (15 - 9 -
dm_mathematics
-----Original Message----- From: [email protected] [mailto:[email protected]] Sent: Friday, January 18, 2002 10:00 AM To: Tori Kuykendall Subject: RE: Hey Tori, First of all Congrats on the new job. Thanks for telling Susan and thinking about me. So tell me a little about what the opportunity is all about
enron_emails
JOHN GRESCHNER, Plaintiff-Appellant, v. No. 03-1193 (D.C. No. 00-RB-167 (BNB)) UNITED STATES OF AMERICA, (D. Colo.) Defendant-Appellee. ORDER AND JUDGMENT * Before LUCERO , McKAY , and TYMKOVICH , Circuit Judges. After examining the briefs and appellate record, this panel has determined unanimously that oral argument would not materially assist the determination of this appeal. See Fed. R. App. P. 34(a)(2); 10th Cir. R. 34.1(G). The case is therefore ordered submitted without oral argument. * This order and judgment is not binding precedent, except under the doctrines of law of the case, res judicata, and collateral estoppel. The court generally disfavors the citation of orders and judgments; nevertheless, an order and judgment may be cited under the terms and conditions of 10th Cir. R. 36.3. John Greschner, proceeding pro se, appeals from the district court’s judgment in favor of defendant, after trial to the court, on claims of negligence brought pursuant to the Federal Tort Claims Act. He also requests appellate counsel. We have jurisdiction over this appeal under 28 U.S.C. § 1291. Appellant challenges the court’s findings of fact, which we review for clear error, Anderson v. City of Bessemer City , 470 U.S. 564, 573 (1985), brings various legal arguments, which we review de novo, Elder v. Holloway , 510 U.S. 510, 516 (1994), and objects to the court’s evidentiary rulings, which we review for abuse of discretion, Faulkner v. Super Valu Stores, Inc. , 3 F.3d 1419, 1433 (10th Cir. 1993). We construe appellant’s pro se pleadings liberally, as required by Haines v. Kerner , 404 U.S. 519, 520 (1972). After our review of the record on appeal and the parties’ briefs in light of these standards and applicable law,
freelaw
Thanks. ~~~ j_lagof I agree, it is the same thing as buying a piece of land and waiting for the area to become more popular and sell later... The issue comes from the fact that buying domains are very cheap and easy, but that's other problem. *btw, I am not saying that I approve people with 1000s of domains just waiting for someone interested, but the business idea is the same. ~~~ dkarl Intentionally provocative question: So you think domain squatting is ethical if it's done occasionally and unsystematically, but not if it's done in an efficient and industrious manner? ~~~ ohashi If we use the real definition, it doesn't matter, if you break trademark law, you break trademark law. ~~~ dkarl Your definition doesn't match how I usually see the term used, so I don't understand how it's the real one. Sure, it's written into law that way, but legal jargon doesn't supersede actual widespread usage except in a legal context. When people say "domain squatting" or "cybersquatting," they mean speculatively buying and holding a domain with no intention of using it, hoping to sell it later when it becomes valuable to someone else. (And no, putting up a generic advertising search page does not qualify as "using" it for the purposes of this definition.) ~~~ ohashi Then what is 'using'? Please define it and think about the implications for domain name registrations at all levels. ------ pg I discourage it. People will always look for you (and worse still, send you mail) at the dot com. And there are lots of decent dot com names still available. ~~~ decadentcactus Wouldn't that also depend on the target audience of the site? If a site was targeted at the same people that use HN for example, I doubt they'd have a problem with the site using a .net ~~~ davidw What if they only sort of peripherally remember the name? It's about finding it, rather than using it. ~~~ zepolen Most people (even geeks) use google to find a site they don't remember the exact url for, and google
hackernews
The cytochromes P-450 are central to the metabolism of xenobiotics and drugs and to the activation and detoxification of carcinogens. Whether a potentially carcinogenic molecule is metabolized to an active carcinogen or to an excretable form may depend on the activity and substrate specificity of the forms of the P-450s which predominate in the target tissue. As a result of this, susceptibility to cancer induction may well depend on the regulation of expression of the genes for specific
nih_exporter
A unique BRCA1 mutation identified in Mongolia. This is a case report of genetic assessment conducted on a family residing in the third world where two sisters have presented with early onset ovarian cancer. Protein truncation testing and DNA sequencing identified a unique mutation on exon 11 (3452delA) of the BRCA1 gene. Buccal swab testing of three siblings and three offspring showed that half of the family members carried the same mutation. Currently, genetic testing in third-world countries is conducted within
pubmed_abstracts
![**Figure 3.** Antiapoptotic effects of argon and xenon. (**A and B**) Wild-type human osteosarcoma U2OS cells were left untreated or treated with 1 µM staurosporine (STS), 50 µM Z-VAD-fmk (Z-VAD), or both in control atmospheric conditions (N~2~) or in the presence of gas mixtures, in which N~2~ was specifically replaced with Ar or Xe, for 8 h. Thereafter, cells were processed for the cytofluorometric assessment of apoptosis-related upon DiOC~6~(3)/propidium iodide (PI) co-staining. Representative dot plots are depicted in (**A**), while quantitative data are in (**B**). In (**B**), black and white column illustrate the percentage of dead (PI^+^) or dying (PI^-^DiOC~6~\[3\]^low^) cells, respectively (means ± SD). \**P* \< 0.05 (Student *t* test), as compared with untreated cells maintained in control atmospheric conditions. \#*P* \< 0.05 (Student *t*-test), as compared with cells treated with STS in control atmospheric conditions; ns, non significant (Student *t* test), as compared with cells treated with STS and Z-VAD in equal atmospheric conditions.](cc-12-2636-g3){#F3} To further substantiate the capacity of Ar and Xe to interfere with the intrinsic pathway of apoptosis, we measured the capacity of these noble gases to limit the cytosolic redistribution of cytochrome *c* and the subsequent activation of caspase-3 as triggered by STS. To this aim, we employed a 2-color fluorescence staining protocol that allows for the combined assessment of cytochrome *c* subcellular localization (changing from a punctuate, filamentous mitochondrial pattern to a diffuse, uniform distribution in the course of apoptosis) and caspase-3 proteolytic activation (generating a neo-epitope which can be recognized by means of specific monoclonal antibodies). Ar and Xe were indeed able to reduce the frequency of cells that, in response to STS, exhibited the mitochondrial release of cytochrome *c* and the activation of caspase-3 ([Fig. 4](#F4){ref-type="fig"}). ![**Figure 4.** Argon- and xenon-mediated inhibition of mitochondrial membrane permeabilization and caspase activation. (**A--C**) Wild-type human osteosarcoma U2OS cells
pubmed_central
eqn = r*\!\( \*SubscriptBox[\(∂\), \(t\)]\(T[t, r, z]\)\) - r*k*\!\( \*SubscriptBox[\(∂\), \(z, z\)]\(T[t, r, z]\)\) - k*\!\( \*SubscriptBox[\(∂\), \(r\)]\(T[t, r, z]\)\) - k*r*\!\( \*SubscriptBox[\(∂\), \(r, r\)]\(T[t, r, z]\)\); Subscript[Γ, D] = {DirichletCondition[T[t, r, z] == Ti, z == Ltot], DirichletCondition[T[t, r, z] == Ti, r == R]}; BCr = NDSolveValue[{eqn == 0, Subscript[Γ, D], \!\( \*SubscriptBox[\(∂\), \(r\)]\(T[t, 0, z]\)\) == 0, \!\( \*SubscriptBox[\(∂\), \(z\)]\(T[t, r, 0]\)\) == -100, T[0, r, z] == Ti}, T, {t, 0, tf}, {r, 0, R}, {z, 0, Ltot}]; A: With v[x, t] the dependent variable, and x the spatial independent variable ranging from x1 to x2, the requested boundary conditions are, v[x1, t] == 0 (D[v[x, t], x] /. x -> x2) == 0 In answer to the OP's comment below, these and any other boundary and initial conditions are included in the first argument of NDSolveValue, as illustrated by several of the Basic Examples in the documentation. Edit As noted in my comment below, the question's recently added code can be made to work with the change, r0 = .1; BCr = NDSolveValue[{eqn == 0, Subscript[Γ, D], (D[T[t, r, z], z] /. z -> 0) == 0, (D[T[t, r, z], r]
stackexchange
2. The Prior Art In Germany, crude salt obtained from potash deposits contains up to 75% sodium chloride and various secondary components such as magnesium and calcium in the form of chlorides, sulfates and bromides. The quality standard of the potassium chloride produced therefrom has a content of valuable substances of about 60% to 62% K.sub.2 O, which conforms to a purity of 95% to 98% potassium chloride in the finished product. In the extraction processes, traces of heavy metals (chromium, nickel, iron, molybdenum and vanadium) may get into the salt as well, conditioned by the materials of the plant equipment. Since the impurities are present in different orders of magnitude, the problem of product refinement is manifold. An enhancement of the product primarily means increasing the overall purity, which has to be equated to a selective reduction of certain impurities. Furthermore, for the use of the potassium chloride in practical life, the grain size or grain distribution plays an important role. If no "narrow grain cut" is desired exclusively, the "dust-free" product is desirable. Minimizing or eliminating the finest grains, which are responsible for the formation of dust, is one of the most important objectives. In the discussion of processes already known for the production of potassium chloride products with higher purity, the fractionated crystallization of crude salt solutions is not addressed because a purity of more than 98% cannot be obtained with these known processes. U.S. Pat. No. 4,385,902, which corresponds to German PS 2,852,925, proposes a process for the purification of potassium chloride crystals with a potassium chloride content of more than 97.5%, by extraction with a potassium chloride-saturated solution under isothermal conditions of 20.degree. C. to 70.degree. C. In this process, the sodium chloride content of the solution has to be under 35 g/L, preferably under 15 g/L. The treatment lasts 0.5 to 18 hours, whereby the rate of extraction process highly declines as the amounts of sodium chloride extracted increase. Seventy percent of the original sodium chloride content is extracted in the first four hours; the next 20% require a time expenditure of 12 hours. The rate of the process is highly dependent upon the size and structure of the grains and can be influenced only little by raising the temperature. In addition to reducing the sodium chloride content as the main impurity, a reduction of the magnesium, calcium and brom
uspto_backgrounds
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wikipedia_en
The authors gratefully acknowledge discussions with and help in obtaining data from Ron Ekers, Rick Smegal, Peter Hall, Bob Sault, Matthew Bailes, Willem van Stratten, Frank Briggs, Mike Kesteven, Warwick Wilson, Dick Ferris [99]{} J. F. Bell et al. [*Base band data for testing interference mitigation algorithms*]{}, ATNF technical document. http://www.atnf.csiro.au/SKA/ J. S. Bendat, and A. G. Piersol, [*Random Data: Analysis and Measurement Procedures*]{}, Wiley-Interscience, New York, 1971. ISBN 0-471-06470-X R. J. Cohen, “The threat to radio astronomy from radio pollution”, [*Space Policy*]{}, [**5**]{}, pp. 91-93, 1989. W. L. Combrinck, M. E. West, and M. J. Gaylard, “Coexisting with GLONASS: Observing the 1612 MHz Hydroxyl Line”, [*PASP*]{}, [**10 6**]{}, pp. 807-812, 1994. R. D. Ekers and J. F. Bell, “Radio Frequency Interference ” to appear in [*The Universe at Low Radio Frequencies*]{}, IAU Symposium 1 99, Pune, Dec. 1999. “The Elizabeth and Frederick White Conference on Radio Frequency Interference Mitigation Strategies”, http://www.atnf.csiro.au/SKA/intmit/atnf/conf/, 2000. J. Galt, “Interference with Astronomical Observations of OH Masers from the Soviet Union’s GLONASS Satellites”, in [*Light Pollution, Radio Interference, and Space Debris*]{}, ASP Conference Series, Vol. 17, IAU Colloquium 112, 1991, D.L. Crawford, Ed., p13, 1991. J. Herman and H. J. Habing, “Time variations and Shell Si zes of OH Masers in Late-Type Atars”, [*AASS*]{}, [**59**]{}, p. 523, 1985. , Coordinat ion Scientific Information Center, Moscow, Russia. Available in PDF form from www.nz.dlr
arxiv