Datasets:

zifeng-ai
/

TrialPanorama-database

study_id stringlengths 3 11	study_source stringclasses 2 values	adverse_event_name stringlengths 1 100	adverse_event_description stringlengths 61 374 ⌀	is_serious bool 2 classes	meddra_id stringlengths 4 8	meddra_id_type stringclasses 3 values
NCT00000125	ClinicalTrials.gov	Ocular Serious Adverse Events (OHTS I, June 2002)	Organ System: Eye disorders Notes: Specific ocular serious adverse events are unknown because they were only collected with regard to organ system. Frequency: 12 affected / 819 at risk	true	None	null
NCT00000125	ClinicalTrials.gov	Ocular Adverse Event (Not Serious)	Organ System: Eye disorders Notes: Adverse Events that were not serious. Frequency: 481 affected / 819 at risk	false	None	null
NCT00000125	ClinicalTrials.gov	Ocular Serious Adverse Events (OHTS I, June 2002)	Organ System: Eye disorders Notes: Specific ocular serious adverse events are unknown because they were only collected with regard to organ system. Frequency: 13 affected / 817 at risk	true	None	null
NCT00000125	ClinicalTrials.gov	Ocular Adverse Event (Not Serious)	Organ System: Eye disorders Notes: Adverse Events that were not serious. Frequency: 570 affected / 817 at risk	false	None	null
NCT00000134	ClinicalTrials.gov	Neutropenia	Organ System: Blood and lymphatic system disorders Frequency: 32 affected / 88 at risk	true	10029354	PT
NCT00000134	ClinicalTrials.gov	Thrombocytopenia	Organ System: Blood and lymphatic system disorders Frequency: 14 affected / 88 at risk	true	10043554	PT
NCT00000134	ClinicalTrials.gov	Hospitalizations	Organ System: Infections and infestations Frequency: 7 affected / 88 at risk	false	None	null
NCT00000134	ClinicalTrials.gov	Neutropenia	Organ System: Blood and lymphatic system disorders Frequency: 41 affected / 93 at risk	true	10029354	PT
NCT00000134	ClinicalTrials.gov	Thrombocytopenia	Organ System: Blood and lymphatic system disorders Frequency: 8 affected / 93 at risk	true	10043554	PT
NCT00000134	ClinicalTrials.gov	Hospitalizations	Organ System: Infections and infestations Frequency: 7 affected / 93 at risk	false	None	null
NCT00000134	ClinicalTrials.gov	Neutropenia	Organ System: Blood and lymphatic system disorders Frequency: 51 affected / 93 at risk	true	10029354	PT
NCT00000134	ClinicalTrials.gov	Thrombocytopenia	Organ System: Blood and lymphatic system disorders Frequency: 15 affected / 93 at risk	true	10043554	PT
NCT00000134	ClinicalTrials.gov	Hospitalizations	Organ System: Infections and infestations Frequency: 10 affected / 93 at risk	false	None	null
NCT00000136	ClinicalTrials.gov	Opportunistic infection	Organ System: Immune system disorders Frequency: 60 affected / 107 at risk	true	10030901	PT
NCT00000136	ClinicalTrials.gov	Opportunistic infection	Organ System: Immune system disorders Frequency: 73 affected / 127 at risk	true	10030901	PT
NCT00000142	ClinicalTrials.gov	Proteinuria 2+	Organ System: Blood and lymphatic system disorders Frequency: 3 affected / 26 at risk	true	None	null
NCT00000142	ClinicalTrials.gov	Proteinuria 2+	Organ System: Blood and lymphatic system disorders Frequency: 13 affected / 26 at risk	true	None	null
NCT00000142	ClinicalTrials.gov	Serum creatinine level >= 133 umol/L (1.5 mg/dL)	Organ System: Blood and lymphatic system disorders Frequency: 2 affected / 26 at risk	false	None	null
NCT00000142	ClinicalTrials.gov	Proteinuria 2+	Organ System: Blood and lymphatic system disorders Frequency: 8 affected / 12 at risk	true	None	null
NCT00000142	ClinicalTrials.gov	Serum creatinine level >= 133 umol/L (1.5 mg/dL)	Organ System: Blood and lymphatic system disorders Frequency: 2 affected / 12 at risk	false	None	null
NCT00000378	ClinicalTrials.gov	Orthostatic hypotension	Organ System: Cardiac disorders Frequency: 2 affected / 58 at risk	false	10031127	PT
NCT00000378	ClinicalTrials.gov	Orthostatic hypotension	Organ System: Cardiac disorders Frequency: 4 affected / 52 at risk	false	10031127	PT
NCT00000392	ClinicalTrials.gov	Death	Organ System: Immune system disorders Frequency: 8 affected / 106 at risk	true	10011906	PT
NCT00000392	ClinicalTrials.gov	Depression or Irritability	Organ System: Psychiatric disorders Frequency: 7 affected / 106 at risk	false	None	null
NCT00000392	ClinicalTrials.gov	Rash	Organ System: Skin and subcutaneous tissue disorders Frequency: 34 affected / 106 at risk	false	10037844	PT
NCT00000392	ClinicalTrials.gov	Nasal congestion	Organ System: Respiratory, thoracic and mediastinal disorders Frequency: 12 affected / 106 at risk	false	10028735	PT
NCT00000392	ClinicalTrials.gov	Proteinuria	Organ System: Renal and urinary disorders Frequency: 18 affected / 106 at risk	false	10037032	PT
NCT00000392	ClinicalTrials.gov	Eosinophilia	Organ System: Blood and lymphatic system disorders Frequency: 4 affected / 106 at risk	false	10014950	PT
NCT00000392	ClinicalTrials.gov	Death	Organ System: Immune system disorders Frequency: 3 affected / 109 at risk	true	10011906	PT
NCT00000392	ClinicalTrials.gov	Depression or Irritability	Organ System: Psychiatric disorders Frequency: 1 affected / 109 at risk	false	None	null
NCT00000392	ClinicalTrials.gov	Rash	Organ System: Skin and subcutaneous tissue disorders Frequency: 42 affected / 109 at risk	false	10037844	PT
NCT00000392	ClinicalTrials.gov	Nasal congestion	Organ System: Respiratory, thoracic and mediastinal disorders Frequency: 5 affected / 109 at risk	false	10028735	PT
NCT00000392	ClinicalTrials.gov	Proteinuria	Organ System: Renal and urinary disorders Frequency: 9 affected / 109 at risk	false	10037032	PT
NCT00000479	ClinicalTrials.gov	Haemorrhagic stroke	Organ System: Blood and lymphatic system disorders Frequency: 27 affected / 9968 at risk	true	10019016	PT
NCT00000479	ClinicalTrials.gov	Haematuria	Organ System: Blood and lymphatic system disorders Frequency: 1534 affected / 9968 at risk	false	10018867	PT
NCT00000479	ClinicalTrials.gov	easy bruising	Organ System: Blood and lymphatic system disorders Frequency: 5297 affected / 9968 at risk	false	None	null
NCT00000479	ClinicalTrials.gov	Epistaxis	Organ System: Blood and lymphatic system disorders Frequency: 1854 affected / 9968 at risk	false	10015090	PT
NCT00000479	ClinicalTrials.gov	report of GI upset	Organ System: Gastrointestinal disorders Frequency: 5969 affected / 9968 at risk	false	None	null
NCT00000479	ClinicalTrials.gov	Haemorrhagic stroke	Organ System: Blood and lymphatic system disorders Frequency: 20 affected / 9971 at risk	true	10019016	PT
NCT00000479	ClinicalTrials.gov	Haematuria	Organ System: Blood and lymphatic system disorders Frequency: 1467 affected / 9971 at risk	false	10018867	PT
NCT00000479	ClinicalTrials.gov	easy bruising	Organ System: Blood and lymphatic system disorders Frequency: 4247 affected / 9971 at risk	false	None	null
NCT00000479	ClinicalTrials.gov	Epistaxis	Organ System: Blood and lymphatic system disorders Frequency: 1703 affected / 9971 at risk	false	10015090	PT
NCT00000479	ClinicalTrials.gov	report of GI upset	Organ System: Gastrointestinal disorders Frequency: 5915 affected / 9971 at risk	false	None	null
NCT00000479	ClinicalTrials.gov	Haemorrhagic stroke	Organ System: Blood and lymphatic system disorders Frequency: 24 affected / 9966 at risk	true	10019016	PT
NCT00000479	ClinicalTrials.gov	Haematuria	Organ System: Blood and lymphatic system disorders Frequency: 1505 affected / 9966 at risk	false	10018867	PT
NCT00000479	ClinicalTrials.gov	easy bruising	Organ System: Blood and lymphatic system disorders Frequency: 5263 affected / 9966 at risk	false	None	null
NCT00000479	ClinicalTrials.gov	Epistaxis	Organ System: Blood and lymphatic system disorders Frequency: 1947 affected / 9966 at risk	false	10015090	PT
NCT00000479	ClinicalTrials.gov	report of GI upset	Organ System: Gastrointestinal disorders Frequency: 5887 affected / 9966 at risk	false	None	null
NCT00000479	ClinicalTrials.gov	Haemorrhagic stroke	Organ System: Blood and lymphatic system disorders Frequency: 21 affected / 9971 at risk	true	10019016	PT
NCT00000479	ClinicalTrials.gov	Haematuria	Organ System: Blood and lymphatic system disorders Frequency: 1411 affected / 9971 at risk	false	10018867	PT
NCT00000479	ClinicalTrials.gov	easy bruising	Organ System: Blood and lymphatic system disorders Frequency: 4247 affected / 9971 at risk	false	None	null
NCT00000479	ClinicalTrials.gov	Epistaxis	Organ System: Blood and lymphatic system disorders Frequency: 1618 affected / 9971 at risk	false	10015090	PT
NCT00000479	ClinicalTrials.gov	report of GI upset	Organ System: Gastrointestinal disorders Frequency: 6000 affected / 9971 at risk	false	None	null
NCT00000575	ClinicalTrials.gov	Phsychiatric (behavior)	Organ System: Psychiatric disorders Frequency: 1 affected / 311 at risk	false	None	null
NCT00000575	ClinicalTrials.gov	Asthma exacerbation	Organ System: Respiratory, thoracic and mediastinal disorders Frequency: 1 affected / 312 at risk	true	None	null
NCT00000575	ClinicalTrials.gov	Dizziness	Organ System: Nervous system disorders Frequency: 1 affected / 312 at risk	false	10013573	PT
NCT00000575	ClinicalTrials.gov	Musculoskeletal (low bone mineral density, back pain)	Organ System: Musculoskeletal and connective tissue disorders Frequency: 1 affected / 312 at risk	false	None	null
NCT00000575	ClinicalTrials.gov	Phsychiatric (behavior)	Organ System: Psychiatric disorders Frequency: 1 affected / 312 at risk	false	None	null
NCT00000575	ClinicalTrials.gov	Respiratory (cough, wheeze, chest tightness, croup)	Organ System: Respiratory, thoracic and mediastinal disorders Frequency: 5 affected / 312 at risk	false	None	null
NCT00000575	ClinicalTrials.gov	Asthma exacerbation	Organ System: Respiratory, thoracic and mediastinal disorders Frequency: 1 affected / 418 at risk	true	None	null
NCT00000575	ClinicalTrials.gov	Psychiatric (hallucinations)	Organ System: Psychiatric disorders Frequency: 2 affected / 418 at risk	true	None	null
NCT00000575	ClinicalTrials.gov	Nephrolithiasis	Organ System: Renal and urinary disorders Frequency: 1 affected / 418 at risk	true	10029148	PT
NCT00000575	ClinicalTrials.gov	Musculoskeletal (low bone mineral density, back pain)	Organ System: Musculoskeletal and connective tissue disorders Frequency: 1 affected / 418 at risk	false	None	null
NCT00000575	ClinicalTrials.gov	Respiratory (cough, wheeze, chest tightness, croup)	Organ System: Respiratory, thoracic and mediastinal disorders Frequency: 1 affected / 418 at risk	false	None	null
NCT00000620	ClinicalTrials.gov	Cardiac failure congestive	Organ System: Cardiac disorders Frequency: 34 affected / 5128 at risk	true	10007559	PT
NCT00000620	ClinicalTrials.gov	Bradycardia, tachycardia, atrial fibrillation	Organ System: Cardiac disorders Frequency: 13 affected / 5128 at risk	true	None	null
NCT00000620	ClinicalTrials.gov	Angina/chest pain	Organ System: Cardiac disorders Frequency: 4 affected / 5128 at risk	true	None	null
NCT00000620	ClinicalTrials.gov	Myocardial infarction	Organ System: Cardiac disorders Frequency: 4 affected / 5128 at risk	true	10028596	PT
NCT00000620	ClinicalTrials.gov	Dizziness, hypotension, syncope	Organ System: Vascular disorders Frequency: 19 affected / 5128 at risk	true	None	null
NCT00000620	ClinicalTrials.gov	Oedema	Organ System: Vascular disorders Frequency: 3 affected / 5128 at risk	true	10030095	PT
NCT00000620	ClinicalTrials.gov	Cerebrovacular accident	Organ System: Vascular disorders Frequency: 1 affected / 5128 at risk	true	None	null
NCT00000620	ClinicalTrials.gov	Cholecystitis	Organ System: Gastrointestinal disorders Frequency: 5 affected / 5128 at risk	true	10008612	PT
NCT00000620	ClinicalTrials.gov	Hepatitis/liver failure	Organ System: Gastrointestinal disorders Frequency: 2 affected / 5128 at risk	true	None	null
NCT00000620	ClinicalTrials.gov	Elevated creatinine, hyponatremia	Organ System: Gastrointestinal disorders Frequency: 2 affected / 5128 at risk	true	None	null
NCT00000620	ClinicalTrials.gov	Gastrointestinal haemorrhage	Organ System: Gastrointestinal disorders Frequency: 1 affected / 5128 at risk	true	10017955	PT
NCT00000620	ClinicalTrials.gov	Pancreatitis	Organ System: Endocrine disorders Frequency: 5 affected / 5128 at risk	true	10033645	PT
NCT00000620	ClinicalTrials.gov	Ketoacidosis	Organ System: Endocrine disorders Frequency: 1 affected / 5128 at risk	true	10023379	PT
NCT00000620	ClinicalTrials.gov	Acute or chronic renal failure	Organ System: Renal and urinary disorders Frequency: 8 affected / 5128 at risk	true	None	null
NCT00000620	ClinicalTrials.gov	Angioedema	Organ System: Immune system disorders Frequency: 9 affected / 5128 at risk	true	10002424	PT
NCT00000620	ClinicalTrials.gov	Thrombocytopenia	Organ System: Immune system disorders Frequency: 2 affected / 5128 at risk	true	10043554	PT
NCT00000620	ClinicalTrials.gov	Blood disorder	Organ System: Immune system disorders Frequency: 1 affected / 5128 at risk	true	10061590	PT
NCT00000620	ClinicalTrials.gov	Felodipine toxicity	Organ System: Immune system disorders Frequency: 1 affected / 5128 at risk	true	None	null
NCT00000620	ClinicalTrials.gov	Myositis	Organ System: Musculoskeletal and connective tissue disorders Frequency: 2 affected / 5128 at risk	true	10028653	PT
NCT00000620	ClinicalTrials.gov	Rhabdomyolisis	Organ System: Musculoskeletal and connective tissue disorders Frequency: 1 affected / 5128 at risk	true	None	null
NCT00000620	ClinicalTrials.gov	Fractures	Organ System: Musculoskeletal and connective tissue disorders Frequency: 1 affected / 5128 at risk	true	None	null
NCT00000620	ClinicalTrials.gov	Macular oedema	Organ System: Eye disorders Frequency: 1 affected / 5128 at risk	true	10025415	PT
NCT00000620	ClinicalTrials.gov	Vision blurred	Organ System: Eye disorders Frequency: 1 affected / 5128 at risk	true	10047513	PT
NCT00000620	ClinicalTrials.gov	Dyspnoea	Organ System: Respiratory, thoracic and mediastinal disorders Frequency: 1 affected / 5128 at risk	true	10013968	PT
NCT00000620	ClinicalTrials.gov	Motor vehicle accident (fatal)	Organ System: Injury, poisoning and procedural complications Frequency: 3 affected / 5128 at risk	true	None	null
NCT00000620	ClinicalTrials.gov	Hyperkalaemia	Organ System: General disorders Frequency: 6 affected / 5128 at risk	true	10020646	PT
NCT00000620	ClinicalTrials.gov	Severe fluid retention	Organ System: General disorders Frequency: 3 affected / 5128 at risk	true	None	null
NCT00000620	ClinicalTrials.gov	Dehydration	Organ System: General disorders Frequency: 1 affected / 5128 at risk	true	10012174	PT
NCT00000620	ClinicalTrials.gov	Hyperosmolar nonketotic coma	Organ System: General disorders Frequency: 1 affected / 5128 at risk	true	None	null
NCT00000620	ClinicalTrials.gov	Toxic metabolic enecphalopathy	Organ System: General disorders Frequency: 1 affected / 5128 at risk	true	None	null
NCT00000620	ClinicalTrials.gov	Cardiac failure congestive	Organ System: Cardiac disorders Frequency: 12 affected / 5123 at risk	true	10007559	PT
NCT00000620	ClinicalTrials.gov	Bradycardia, tachycardia, atrial fibrillation	Organ System: Cardiac disorders Frequency: 4 affected / 5123 at risk	true	None	null
NCT00000620	ClinicalTrials.gov	Angina/chest pain	Organ System: Cardiac disorders Frequency: 5 affected / 5123 at risk	true	None	null
NCT00000620	ClinicalTrials.gov	Myocardial infarction	Organ System: Cardiac disorders Frequency: 5 affected / 5123 at risk	true	10028596	PT
NCT00000620	ClinicalTrials.gov	Dizziness, hypotension, syncope	Organ System: Vascular disorders Frequency: 17 affected / 5123 at risk	true	None	null
NCT00000620	ClinicalTrials.gov	Oedema	Organ System: Vascular disorders Frequency: 1 affected / 5123 at risk	true	10030095	PT

End of preview. Expand in Data Studio

Quick start

The easiest way to download the dataset to your local is to use huggingface-cli. The specific command you can use is

huggingface-cli download zifeng-ai/TrialPanorama-database --local-dir LOCAL_DIR --repo-type dataset

where LOCAL_DIR should be replaced with the target directory you want to save your dataset to.

Update history

Aug.4 2025: updated tables with the full set of studies

Dataset website: https://ryanwangzf.github.io/projects/trialpanorama

TrialPanorama

TrialPanorama is a large-scale, structured database and benchmark designed to support AI-driven tasks in clinical trial workflows—including systematic review and trial design. This repo hosts the database of clinical trials. To conduct benchmarking experiments on trial design and systematic review asks, check this dataset instead: https://huggingface.co/datasets/zifeng-ai/TrialPanorama-benchmark

Dataset Overview

Aggregates over 1M clinical trial records from ClinicalTrials and PubMed
Captures standardized elements such as trial setups, interventions, conditions, biomarkers, outcomes, and links to biomedical ontologies (e.g. DrugBank, MedDRA).
Structured into multiple conceptual clusters and tables (e.g. trial-level attributes, protocol design, results, links)

Benchmark Suite

The dataset supports a suite of 8 benchmark tasks across two domains:

Systematic Review:
- Study search
- Study screening
- Evidence summarization
Trial Design:
- Arm design
- Eligibility criteria
- Endpoint selection
- Sample size estimation
- Trial completion assessment

Data Schema (Major Tables)

studies — core metadata (e.g. study_id, intervention type, sponsor type, start year, trial phase, recruitment status)
protocols, interventions, conditions, biomarkers, outcomes, results — each standardized to a unified schema

Use Cases

Developing and evaluating LLMs and ML models for clinical trial-related tasks
Benchmarking AI capabilities in trial search, screening, design, and summarization
Conducting meta-analyses and exploring evidence synthesis across disease areas
Enabling interoperability with biomedical ontologies to support richer clinical trial reasoning

Getting Started

Citation

If you use TrialPanorama, we appreciate your citation:

@article{wang2025trialpanorama,
  title={TrialPanorama: Database and Benchmark for Systematic Review and Design of Clinical Trials},
  author={Wang, Zifeng and Jin, Qiao and Lin, Jiacheng and Gao, Junyi and Pradeepkumar, Jathurshan and Jiang, Pengcheng and Danek, Benjamin and Lu, Zhiyong and Sun, Jimeng},
  journal={arXiv preprint arXiv:2505.16097},
  year={2025}
}

Downloads last month: 1,040

Size of the auto-converted Parquet files (First 5GB per split):

2.28 GB

Number of rows (First 5GB per split):

26,719,937

Estimated number of rows:

26,719,517