Ayush2609/auto_content · Datasets at Hugging Face

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α, increased interleukin-6 (IL-6), and did not affect IL-1
The coexistence of these risk factors may overshadow the
and captopril on lipid parameters in patients with type II diabetes
ISSN 1064-1963 print/1525-6006 online
untreated hypertensive patients and tested two different
0.89 � 0.12
The patients who did not smoke nor had caffeinated
cholesterol level: a meta-analysis of population-based prospective
angiotensin II receptor antagonists. Blood Press Suppl 2001;
Systolic and diastolic BP were significantly decreased
For personal use only.
HDL, TG, and TC levels. We do not know whether this is
Clinical and Experimental Hypertension
concentrations
that pose a risk for cardiovascular disease are important for
of an alpha-adrenergic blocker and an inhibitor of the angiotensin
Abbreviations: HDL – high density lipoprotein; LDL – low density
The study was conducted in Departments of Internal
Angiology 2009; 60(2):217–220.
6/16
losartan on insulin sensitivity, lipid profile, and endothelin in
drugs.
sympathoadrenal system. N Engl J Med 1996; 8(334):374–381.
© 2013 Informa Healthcare USA, Inc.
patients with type 2 diabetes or nephropathy (20).
LDL-Lowering Effect of Amlodipine
lipid profile (2,3). Data from our study also confirm the
.421
These findings are in accordance with previous reports
main limitation of our study is the small sample size and
GROUP
.702
AU2700 auto analyzer using reagents from Olympus
Patients of the two groups were matched for age and
unknown. The issue needs to be examined with further
12 weeks of antihypertensive therapy with amlodipine on
serum TC, TG, HDL, LDL (Figure 1), urea, creatinine, uric acid, aspartate aminotransferase, alanine aminotransferase, and hemoglobin levels, white blood cell
Clin Exp Hypertens Downloaded from informahealthcare.com by Nyu Medical Center on 10/16/14
7227 � 1249 .533
449
classes of antihypertensive drugs at the same time. The
.633
Amlodipine, a member of the calcium antagonists of the
It is clear from the present study that different antihypertensives have different effects on serum lipids in newly diagnosed hypertension. Valsartan may have deleterious effects
Differential effects of amlodipine and atorvastatin treatment and
219.3 � 58.5
.631
J Clin Hypertens 2006; 8(8):571–581.
atorvastatin treatment alone. The authors expressed that
[15] Jeppesen J, Hein H, Suadicani P, Gyntelberg F. Relation of high
lipopolysaccharide
Sait Demirkol,3 Fatih Bulucu,2 Kenan Saglam2
Hemoglobin (g/dL)
158.45 � 10.7
is associated with reduced insulin sensitivity and hyperinsulinemia, which in turn may cause dyslipidemia
Zekeriya Arslan,1 Seyit Ahmet Ay,2 Murat Karaman,2 Mustafa Cakar,2 Turgay Celik,3
WBC (�10/ L)
and after treatment were 93.0 � 8.7 and 75.6 �
(8,9). The last mentioned drugs were neutral for lipid
223.6 � 33.5
Age (y)
concentration of low-density lipoprotein cholesterol in plasma,
Angiotensin-2 receptor antagonists, which block
into valsartan group and 21 patients into the amlodipine
were recommended to make lifestyle modifications consisting of regular exercise, weight control, and salt restriction. All participants gave written informed consent. The
a holistic approach. From this perspective, the possible
Clin Exp Hypertens Downloaded from informahealthcare.com by Nyu Medical Center on 10/16/14
[8] Fernández PC, Luque OM, Martell CN, et al. Treatment of
lipoprotein.
Table 3. The serum lipid parameters of the valsartan group at
II receptor blockade on insulin sensitivity and sympathetic
Statistical Analysis
content and writing of this article.
laboratory
Z. Arslan et al.
127.3 � 29.2
.732
© 2013 Informa Healthcare USA, Inc.
antihypertensive drug therapy should also be considered
1999;
is also used to treat coronary artery disease, angina pectoris
Antihypertensive drugs are known to have different
12th week
in the metabolic effects of the angiotensin receptor blockers.
the valsartan group has been reported to decrease TC
Hypertens 1993; 6(11):303–308.
performed on 43 patients with newly diagnosed essential hypertension (group A, n = 21 and group B, n = 22).
with a significant reduction of LDL compared to valsartan. In the treatment of hypertension, prior knowledge of the plasma
[4] Keane W, Eknoyan G. Proteinuria, albuminuria, risk, assessment,
diseases (2), and high triglyceride (TG) and low-density
HDL cholesterol (mg/dL)
essential arterial hypertension with hypercholesterolemia. Effects
[21] Burnier M, Maillard M. The comparative pharmacology of
150.6 � 75.4
47.7 � 12.1
For personal use only.
important in the antihypertensive drug choice. Further
with evidence of any target organ damage from high
.328
LDL 12th week (mg/dL)

α, increased interleukin-6 (IL-6), and did not affect IL-1

The coexistence of these risk factors may overshadow the

and captopril on lipid parameters in patients with type II diabetes

ISSN 1064-1963 print/1525-6006 online

untreated hypertensive patients and tested two different

0.89 � 0.12

The patients who did not smoke nor had caffeinated

cholesterol level: a meta-analysis of population-based prospective

angiotensin II receptor antagonists. Blood Press Suppl 2001;

Systolic and diastolic BP were significantly decreased

For personal use only.

HDL, TG, and TC levels. We do not know whether this is

Clinical and Experimental Hypertension

concentrations

that pose a risk for cardiovascular disease are important for

of an alpha-adrenergic blocker and an inhibitor of the angiotensin

Abbreviations: HDL – high density lipoprotein; LDL – low density

The study was conducted in Departments of Internal

Angiology 2009; 60(2):217–220.

6/16

losartan on insulin sensitivity, lipid profile, and endothelin in

drugs.

sympathoadrenal system. N Engl J Med 1996; 8(334):374–381.

patients with type 2 diabetes or nephropathy (20).

LDL-Lowering Effect of Amlodipine

lipid profile (2,3). Data from our study also confirm the

.421

These findings are in accordance with previous reports

main limitation of our study is the small sample size and

GROUP

.702

AU2700 auto analyzer using reagents from Olympus

Patients of the two groups were matched for age and

unknown. The issue needs to be examined with further

12 weeks of antihypertensive therapy with amlodipine on

serum TC, TG, HDL, LDL (Figure 1), urea, creatinine, uric acid, aspartate aminotransferase, alanine aminotransferase, and hemoglobin levels, white blood cell

Clin Exp Hypertens Downloaded from informahealthcare.com by Nyu Medical Center on 10/16/14

7227 � 1249 .533

449

classes of antihypertensive drugs at the same time. The

.633

Amlodipine, a member of the calcium antagonists of the

It is clear from the present study that different antihypertensives have different effects on serum lipids in newly diagnosed hypertension. Valsartan may have deleterious effects

Differential effects of amlodipine and atorvastatin treatment and

219.3 � 58.5

.631

J Clin Hypertens 2006; 8(8):571–581.

atorvastatin treatment alone. The authors expressed that

[15] Jeppesen J, Hein H, Suadicani P, Gyntelberg F. Relation of high

lipopolysaccharide

Sait Demirkol,3 Fatih Bulucu,2 Kenan Saglam2

Hemoglobin (g/dL)

158.45 � 10.7

is associated with reduced insulin sensitivity and hyperinsulinemia, which in turn may cause dyslipidemia

Zekeriya Arslan,1 Seyit Ahmet Ay,2 Murat Karaman,2 Mustafa Cakar,2 Turgay Celik,3

WBC (�10/ L)

and after treatment were 93.0 � 8.7 and 75.6 �

(8,9). The last mentioned drugs were neutral for lipid

223.6 � 33.5

Age (y)

concentration of low-density lipoprotein cholesterol in plasma,

Angiotensin-2 receptor antagonists, which block

into valsartan group and 21 patients into the amlodipine

were recommended to make lifestyle modifications consisting of regular exercise, weight control, and salt restriction. All participants gave written informed consent. The

a holistic approach. From this perspective, the possible

Clin Exp Hypertens Downloaded from informahealthcare.com by Nyu Medical Center on 10/16/14

[8] Fernández PC, Luque OM, Martell CN, et al. Treatment of

lipoprotein.

Table 3. The serum lipid parameters of the valsartan group at

II receptor blockade on insulin sensitivity and sympathetic

Statistical Analysis

content and writing of this article.

laboratory

Z. Arslan et al.

127.3 � 29.2

.732

antihypertensive drug therapy should also be considered

1999;

is also used to treat coronary artery disease, angina pectoris

Antihypertensive drugs are known to have different

12th week

in the metabolic effects of the angiotensin receptor blockers.

the valsartan group has been reported to decrease TC

Hypertens 1993; 6(11):303–308.

performed on 43 patients with newly diagnosed essential hypertension (group A, n = 21 and group B, n = 22).

with a significant reduction of LDL compared to valsartan. In the treatment of hypertension, prior knowledge of the plasma

[4] Keane W, Eknoyan G. Proteinuria, albuminuria, risk, assessment,

diseases (2), and high triglyceride (TG) and low-density

HDL cholesterol (mg/dL)

essential arterial hypertension with hypercholesterolemia. Effects

[21] Burnier M, Maillard M. The comparative pharmacology of

150.6 � 75.4

47.7 � 12.1

For personal use only.

important in the antihypertensive drug choice. Further

with evidence of any target organ damage from high

.328

LDL 12th week (mg/dL)