Datasets:
BrentLab
/
yeast_genome_resources

Dataset card Data Studio Files
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10 values
locus_tag
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649
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gene
YAL069W
YAL069W
unknown_1
sgd/S288C_reference_genome_R64-3-1_20210421
Dubious open reading frame B unlikely to encode a functional protein C based on available experimental and comparative sequence data
538
792
+
gene
YAL068W-A
YAL068W-A
unknown_2
sgd/S288C_reference_genome_R64-3-1_20210421
Dubious open reading frame B unlikely to encode a functional protein C based on available experimental and comparative sequence data B identified by gene-trapping C microarray-based expression analysis C and genome-wide homology searching
1,807
2,169
-
gene
YAL068C
PAU8
PAU8,seripauperin_PAU8
sgd/S288C_reference_genome_R64-3-1_20210421
Protein of unknown function B member of the seripauperin multigene family encoded mainly in subtelomeric regions
2,480
2,707
+
gene
YAL067W-A
YAL067W-A
unknown_4
sgd/S288C_reference_genome_R64-3-1_20210421
Putative protein of unknown function B identified by gene-trapping C microarray-based expression analysis C and genome-wide homology searching
7,235
9,016
-
gene
YAL067C
SEO1
SEO1,putative_permease_SEO1
sgd/S288C_reference_genome_R64-3-1_20210421
Putative permease B member of the allantoate transporter subfamily of the major facilitator superfamily B mutation confers resistance to ethionine sulfoxide
10,091
10,399
+
gene
YAL066W
YAL066W
unknown_6
sgd/S288C_reference_genome_R64-3-1_20210421
Dubious open reading frame B unlikely to encode a functional protein C based on available experimental and comparative sequence data
11,565
11,951
-
gene
YAL065C
YAL065C
unknown_7
sgd/S288C_reference_genome_R64-3-1_20210421
Putative protein of unknown function B shows sequence similarity to FLO1 and other flocculins
12,046
12,426
+
gene
YAL064W-B
YAL064W-B
unknown_8
sgd/S288C_reference_genome_R64-3-1_20210421
Fungal-specific protein of unknown function
13,363
13,743
-
gene
YAL064C-A
TDA8
TDA8,YAL065C-A
sgd/S288C_reference_genome_R64-3-1_20210421
Putative protein of unknown function B null mutant is sensitive to expression of the top1-T722A allele B not an essential gene
21,566
21,850
+
gene
YAL064W
YAL064W
unknown_10
sgd/S288C_reference_genome_R64-3-1_20210421
Protein of unknown function B may interact with ribosomes C based on co-purification experiments
22,395
22,685
-
gene
YAL063C-A
YAL063C-A
unknown_11
sgd/S288C_reference_genome_R64-3-1_20210421
Putative protein of unknown function B identified by expression profiling and mass spectrometry
24,000
27,968
-
gene
YAL063C
FLO9
FLO9,flocculin_FLO9
sgd/S288C_reference_genome_R64-3-1_20210421
Lectin-like protein with similarity to Flo1p B thought to be expressed and involved in flocculation
31,567
32,940
+
gene
YAL062W
GDH3
GDH3,FUN51,glutamate_dehydrogenase__NADP_+___GDH3
sgd/S288C_reference_genome_R64-3-1_20210421
NADP + -dependent glutamate dehydrogenase B synthesizes glutamate from ammonia and alpha-ketoglutarate B rate of alpha-ketoglutarate utilization differs from Gdh1p B expression regulated by nitrogen and carbon sources B GDH3 has a paralog C GDH1 C that arose from the whole genome duplication
33,448
34,701
+
gene
YAL061W
BDH2
BDH2,putative_dehydrogenase_BDH2
sgd/S288C_reference_genome_R64-3-1_20210421
Putative medium-chain alcohol dehydrogenase with similarity to BDH1 B transcription induced by constitutively active PDR1 and PDR3
35,155
36,303
+
gene
YAL060W
BDH1
BDH1,_R_CR_-butanediol_dehydrogenase,BDH
sgd/S288C_reference_genome_R64-3-1_20210421
NAD-dependent R CR -butanediol dehydrogenase B catalyzes oxidation of R CR -2 C3-butanediol to R -acetoin C oxidation of meso-butanediol to S -acetoin C and reduction of acetoin B enhances use of C3-butanediol as an aerobic carbon source
36,496
36,918
-
gene
YAL059C-A
YAL059C-A
unknown_16
sgd/S288C_reference_genome_R64-3-1_20210421
Dubious open reading frame B unlikely to encode a functional protein C based on available experimental and comparative sequence data B partially overlaps verified gene ECM1/YAL059W
36,509
37,147
+
gene
YAL059W
ECM1
ECM1
sgd/S288C_reference_genome_R64-3-1_20210421
Pre-ribosomal factor involved in S ribosomal protein subunit export B associates with the pre-60S particle B shuttles between the nucleus and cytoplasm
37,464
38,972
+
gene
YAL058W
CNE1
CNE1,FUN48,calnexin
sgd/S288C_reference_genome_R64-3-1_20210421
Calnexin B integral membrane ER chaperone involved in folding and quality control of glycoproteins B chaperone activity is inhibited by Mpd1p C with which Cne1p interacts B % identical to mammalian calnexin B Ca+ binding not yet shown in yeast
38,696
39,046
-
gene
YAL056C-A
YAL056C-A
YAL058C-A
sgd/S288C_reference_genome_R64-3-1_20210421
Dubious open reading frame B unlikely to encode a functional protein C based on available experimental and comparative sequence data
39,259
41,901
+
gene
YAL056W
GPB2
GPB2,KRH1
sgd/S288C_reference_genome_R64-3-1_20210421
Multistep regulator of cAMP-PKA signaling B inhibits PKA downstream of Gpa2p and Cyr1p C thereby increasing cAMP dependency B inhibits Ras activity through direct interactions with Ira1p/2p B regulated by G-alpha protein Gpa2p B GPB2 has a paralog C GPB1 C that arose from the whole genome duplication
42,177
42,719
+
gene
YAL055W
PEX22
PEX22,YAF5,ubiquitin-protein_transferase_activating_protein_PEX22
sgd/S288C_reference_genome_R64-3-1_20210421
Putative peroxisomal membrane protein B required for import of peroxisomal proteins B functionally complements a Pichia pastoris pex22 mutation
42,881
45,022
-
gene
YAL054C
ACS1
ACS1,FUN44,acetate--CoA_ligase_
sgd/S288C_reference_genome_R64-3-1_20210421
Acetyl-coA synthetase isoform B along with Acs2p C acetyl-coA synthetase isoform is the nuclear source of acetyl-coA for histone acetylation B expressed during growth on nonfermentable carbon sources and under aerobic conditions
45,899
48,250
+
gene
YAL053W
FLC2
FLC2,flavin_adenine_dinucleotide_transporter_FLC2
sgd/S288C_reference_genome_R64-3-1_20210421
Putative calcium channel involved in calcium release under hypotonic stress B required for uptake of FAD into endoplasmic reticulum B involved in cell wall maintenance B FLC2 has a paralog C YOR365C C that arose from the whole genome duplication
48,564
51,707
+
gene
YAL051W
OAF1
OAF1,YAF1,oleate-activated_transcription_factor_OAF1
sgd/S288C_reference_genome_R64-3-1_20210421
Oleate-activated transcription factor B subunit of a heterodimeric complex with Pip2p C which binds to oleate-response elements ORE in the promoter of genes involved in beta-oxidation of fatty acids C peroxisome organization and biogenesis C activating transcription in the presence of oleate B regulates chromatin silencing at telomeres B involved in diauxic shift B OAF1 has a paralog C PIP2 C that arose from the whole genome duplication
51,855
52,595
-
gene
YAL049C
AIM2
AIM2,protein_AIM2
sgd/S288C_reference_genome_R64-3-1_20210421
Cytoplasmic protein involved in mitochondrial function or organization B null mutant displays reduced frequency of mitochondrial genome loss B potential Hsp82p interactor
52,801
54,789
-
gene
YAL048C
GEM1
GEM1,ERMES_complex_Ca_+_-binding_regulatory_GTPase_GEM1,GON1
sgd/S288C_reference_genome_R64-3-1_20210421
Outer mitochondrial membrane GTPase C subunit of the ERMES complex B potential regulatory subunit of the ERMES complex that links the ER to mitochondria and may promote inter-organellar calcium and phospholipid exchange as well as coordinating mitochondrial DNA replication and growth B cells lacking Gem1p contain collapsed C globular C or grape-like mitochondria B ortholog of metazoan Miro GTPases
54,584
54,913
+
gene
YAL047W-A
YAL047W-A
unknown_27
sgd/S288C_reference_genome_R64-3-1_20210421
Dubious open reading frame B unlikely to encode a functional protein C based on available experimental and comparative sequence data B partially overlaps ORF GEM1/YAL048C
54,989
56,857
-
gene
YAL047C
SPC72
SPC72,LDB4,gamma-tubulin_complex_subunit_SPC72
sgd/S288C_reference_genome_R64-3-1_20210421
Gamma-tubulin small complex gamma-TuSC receptor B recruits the gamma-TuSC complex to the cytoplasmic side of the SPB C connecting nuclear microtubules to the SPB B involved in astral microtubule formation C stabilization C and with Stu2p C anchoring astral MTs at the cytoplasmic face of the SPB C and regulating plus-end MT dynamics B regulated by Cdc5 kinase
57,029
57,385
-
gene
YAL046C
BOL3
BOL3,AIM1
sgd/S288C_reference_genome_R64-3-1_20210421
Protein involved in Fe-S cluster transfer to mitochondrial clients B protects [4Fe-4S] clusters from damage due to oxidative stress by acting along with Nfu1p at a late step in the transfer of [4Fe-4S] clusters from the ISA complex to mitochondrial client proteins like lipoate synthase and succinate dehydrogenase B sequence similarity to human BOLA family member C BOLA3 C mutations of which are associated with Multiple Mitochondria Dysfunctions Syndrome MMDS2
57,488
57,796
-
gene
YAL045C
YAL045C
unknown_30
sgd/S288C_reference_genome_R64-3-1_20210421
Dubious open reading frame B unlikely to encode a functional protein C based on available experimental and comparative sequence data B almost completely overlaps YAL044W-A
57,518
57,850
+
gene
YAL044W-A
BOL1
BOL1
sgd/S288C_reference_genome_R64-3-1_20210421
Mitochondrial matrix protein involved in Fe-S cluster biogenesis B facilitates [4Fe-2S] cluster inception into mitochondrial proteins such as lipoate synthase and succinate dehydrogenase B interacts and may function with Grx5p at an early step in Fe-S cluster biosynthesis B forms dimeric complexes with Grx5p and Nfu1p that alter the stability of shared Fe/S clusters B sequence similarity to human BOLA family member C BOLA1 and S. pombe uvi31 C a putative DNA repair protein
57,950
58,462
-
gene
YAL044C
GCV3
GCV3,glycine_decarboxylase_subunit_H
sgd/S288C_reference_genome_R64-3-1_20210421
H subunit of the mitochondrial glycine decarboxylase complex B glycine decarboxylase is required for the catabolism of glycine to C10-methylene-THF B also required for all protein lipoylation B expression is regulated by levels of C10-methylene-THF
58,695
61,052
-
gene
YAL043C
PTA1
PTA1,FUN39,RNA-processing_protein_PTA1
sgd/S288C_reference_genome_R64-3-1_20210421
Subunit of holo-CPF B holo-CPF is a multiprotein complex and functional homolog of mammalian CPSF C required for the cleavage and polyadenylation of mRNA and snoRNA ' ends B involved in pre-tRNA processing B binds to the phosphorylated CTD of RNAPII
61,231
61,608
-
gene
YAL042C-A
YAL042C-A
YAL043C-A
sgd/S288C_reference_genome_R64-3-1_20210421
Dubious open reading frame B unlikely to encode a functional protein C based on available experimental and comparative sequence data B partially overlaps verified ORF ERV46/YAL042W B YAL042C-A is a non-essential gene
61,316
62,563
+
gene
YAL042W
ERV46
ERV46,FUN9
sgd/S288C_reference_genome_R64-3-1_20210421
Protein localized to COPII-coated vesicles B forms a complex with Erv41p B involved in the membrane fusion stage of transport
62,840
65,404
+
gene
YAL041W
CDC24
CDC24,CLS4,Rho_family_guanine_nucleotide_exchange_factor_CDC24
sgd/S288C_reference_genome_R64-3-1_20210421
Guanine nucleotide exchange factor GEF for Cdc42p B required for polarity establishment and maintenance C and mutants have morphological defects in bud formation and shmooing B relocalizes from nucleus to cytoplasm upon DNA replication stress B thermosensitivity of the cdc24-4 mutant in the presence of sorbitol is functionally complemented by human CDC42
65,778
67,520
-
gene
YAL040C
CLN3
CLN3,DAF1,FUN10,WHI1,cyclin_CLN3
sgd/S288C_reference_genome_R64-3-1_20210421
G1 cyclin involved in cell cycle progression B activates Cdc28p kinase to promote G1 to S phase transition B plays a role in regulating transcription of other G1 cyclins C CLN1 and CLN2 B regulated by phosphorylation and proteolysis B acetyl-CoA induces CLN3 transcription in response to nutrient repletion to promote cell-cycle entry B cell cycle arrest phenotype of the cln1 cln2 cln3 triple null mutant is complemented by any of human cyclins CCNA2 C CCNB1 C CCNC C CCND1 C or CCNE1
68,716
69,525
-
gene
YAL039C
CYC3
CYC3,CCHL,holocytochrome_c_synthase_CYC3
sgd/S288C_reference_genome_R64-3-1_20210421
Cytochrome c heme lyase holocytochrome c synthase B attaches heme to apo-cytochrome c Cyc1p or Cyc7p in mitochondrial intermembrane space B human homolog HCCS implicated in microphthalmia with linear skin defects MLS C and can complement yeast null mutant
71,786
73,288
+
gene
YAL038W
CDC19
CDC19,PYK1,pyruvate_kinase_CDC19
sgd/S288C_reference_genome_R64-3-1_20210421
Pyruvate kinase B functions as a homotetramer in glycolysis to convert phosphoenolpyruvate to pyruvate C the input for aerobic TCA cycle or anaerobic glucose fermentation respiration B regulated via allosteric activation by fructose bisphosphate B CDC19 has a paralog C PYK2 C that arose from the whole genome duplication
72,326
73,300
-
gene
YAL037C-B
YAL037C-B
unknown_40
sgd/S288C_reference_genome_R64-3-1_20210421
Dubious open reading frame B unlikely to encode a functional protein C based on available experimental and comparative sequence data B identified by gene-trapping C microarray-based expression analysis C and genome-wide homology searching
73,426
73,518
-
gene
YAL037C-A
YAL037C-A
unknown_41
sgd/S288C_reference_genome_R64-3-1_20210421
Putative protein of unknown function
74,020
74,823
+
gene
YAL037W
YAL037W
unknown_42
sgd/S288C_reference_genome_R64-3-1_20210421
Putative protein of unknown function B YAL037W has a paralog C YOR342C C that arose from the whole genome duplication
75,043
76,152
-
gene
YAL036C
RBG1
RBG1,FUN11,GTP-binding_protein_RBG1
sgd/S288C_reference_genome_R64-3-1_20210421
Member of the DRG family of GTP-binding proteins B associates with translating ribosomes B interacts with Tma46p C Ygr250cp C Gir2p and Yap1p via two-hybrid
76,427
79,435
+
gene
YAL035W
FUN12
FUN12,eIF5B,translation_initiation_factor_eIF5B,yIF2
sgd/S288C_reference_genome_R64-3-1_20210421
Translation initiation factor eIF5B B GTPase that promotes Met-tRNAiMet binding to ribosomes and ribosomal subunit joining B promotes GTP-dependent maturation of S rRNA by Nob1p B protein abundance increases in response to DNA replication stress B homolog of bacterial IF2
79,489
79,842
-
gene
YAL034C-B
YAL034C-B
YAL035C-A
sgd/S288C_reference_genome_R64-3-1_20210421
Dubious open reading frame B unlikely to encode a functional protein C based on available experimental and comparative sequence data
79,718
80,587
+
gene
YAL034W-A
MTW1
MTW1,DSN3,MIND_complex_subunit_MTW1,NSL2
sgd/S288C_reference_genome_R64-3-1_20210421
Essential component of the MIND kinetochore complex B joins kinetochore subunits contacting DNA to those contacting microtubules B critical to kinetochore assembly B complex consists of Mtw1p Including Nnf1p-Nsl1p-Dsn1p MIND
80,710
81,951
-
gene
YAL034C
FUN19
FUN19
sgd/S288C_reference_genome_R64-3-1_20210421
Non-essential protein of unknown function B expression induced in response to heat stress B FUN19 has a paralog C YOR338W C that arose from the whole genome duplication
82,706
83,227
+
gene
YAL033W
POP5
POP5,FUN53,RNA-binding_protein_POP5
sgd/S288C_reference_genome_R64-3-1_20210421
Subunit of both RNase MRP and nuclear RNase P B RNase MRP cleaves pre-rRNA C while nuclear RNase P cleaves tRNA precursors to generate mature ' ends and facilitates turnover of nuclear RNAs
83,335
84,474
-
gene
YAL032C
PRP45
PRP45,FUN20,mRNA_splicing_protein_PRP45
sgd/S288C_reference_genome_R64-3-1_20210421
Protein required for pre-mRNA splicing B associates with the spliceosome and interacts with splicing factors Prp22p and Prp46p B orthologous to human transcriptional coactivator SKIP and can activate transcription of a reporter gene
84,669
84,977
+
gene
YAL031W-A
YAL031W-A
unknown_50
sgd/S288C_reference_genome_R64-3-1_20210421
Dubious open reading frame B unlikely to encode a functional protein C based on available experimental and comparative sequence data B partially overlaps ORF GIP4/YAL031C
84,749
87,031
-
gene
YAL031C
GIP4
GIP4,FUN21,protein_phosphatase_regulator_GIP4
sgd/S288C_reference_genome_R64-3-1_20210421
Cytoplasmic protein that regulates protein phosphatase Glc7p B protein overexpression relocalizes Glc7p from the nucleus and prevents chromosome segregation B potential Cdc28p substrate
87,286
87,752
+
gene
YAL030W
SNC1
SNC1,SNAP_receptor_SNC1
sgd/S288C_reference_genome_R64-3-1_20210421
Vesicle membrane receptor protein v-SNARE B involved in the fusion between Golgi-derived secretory vesicles with the plasma membrane B proposed to be involved in endocytosis B member of the synaptobrevin/VAMP family of R-type v-SNARE proteins B SNC1 has a paralog C SNC2 C that arose from the whole genome duplication
87,855
92,270
-
gene
YAL029C
MYO4
MYO4,FUN22,SHE1,myosin_
sgd/S288C_reference_genome_R64-3-1_20210421
Type V myosin motor involved in actin-based transport of cargos B required for mRNA transport C including ASH1 mRNA C and facilitating the growth and movement of ER tubules into the growing bud along with She3p B MYO4 has a paralog C MYO2 C that arose from the whole genome duplication
92,900
94,486
+
gene
YAL028W
FRT2
FRT2,HPH2
sgd/S288C_reference_genome_R64-3-1_20210421
Tail-anchored ER membrane protein of unknown function B interacts with homolog Frt1p B promotes growth in conditions of high Na+ C alkaline pH C or cell wall stress C possibly via a role in posttranslational translocation B potential Cdc28p substrate B FRT2 has a paralog C FRT1 C that arose from the whole genome duplication
94,687
95,472
+
gene
YAL027W
SAW1
SAW1,DNA-binding_protein_SAW1
sgd/S288C_reference_genome_R64-3-1_20210421
5'- and '-flap DNA binding protein B recruits Rad1p-Rad10p to single-strand annealing intermediates with ' non-homologous tails for removal during double-strand break repair B complexes with Rad1p-Rad10p and stimulates its endonuclease activity B green fluorescent protein GFP -fusion protein localizes to the nucleus
95,386
95,823
-
gene
YAL026C-A
YAL026C-A
unknown_56
sgd/S288C_reference_genome_R64-3-1_20210421
Dubious open reading frame B unlikely to encode a functional protein C based on available experimental and comparative sequence data B partially overlaps the uncharacterized ORF YAL027W and the verified gene DRS2
95,630
99,697
-
gene
YAL026C
DRS2
DRS2,FUN38,SWA3,aminophospholipid-translocating_P4-type_ATPase_DRS2
sgd/S288C_reference_genome_R64-3-1_20210421
Trans-golgi network aminophospholipid translocase flippase B maintains membrane lipid asymmetry in post-Golgi secretory vesicles B contributes to clathrin-coated vesicle formation C endocytosis C protein trafficking between the Golgi and endosomal system and the cellular response to mating pheromone B autoinhibited by its C-terminal tail B localizes to the trans-Golgi network B mutations in human homolog ATP8B1 result in liver disease
99,305
99,868
+
ncRNA_gene
YNCA0001W
HRA1
HRA1
sgd/S288C_reference_genome_R64-3-1_20210421
Non-protein-coding RNA B substrate of RNase P C possibly involved in rRNA processing C specifically maturation of S precursor into the mature S rRNA
100,225
101,145
-
gene
YAL025C
MAK16
MAK16,ribosome_biosynthesis_protein_MAK16
sgd/S288C_reference_genome_R64-3-1_20210421
Essential nuclear protein B constituent of S pre-ribosomal particles B required for maturation of S and .8S rRNAs B required for maintenance of M1 satellite double-stranded RNA of the L-A virus
101,565
105,872
-
gene
YAL024C
LTE1
LTE1,MSI2,mitotic_regulator_LTE1
sgd/S288C_reference_genome_R64-3-1_20210421
Protein similar to GDP/GTP exchange factors B without detectable GEF activity B required for asymmetric localization of Bfa1p at daughter-directed spindle pole bodies and for mitotic exit at low temperatures
106,272
108,551
-
gene
YAL023C
PMT2
PMT2,FUN25,dolichyl-phosphate-mannose-protein_mannosyltransferase_PMT2
sgd/S288C_reference_genome_R64-3-1_20210421
Protein O-mannosyltransferase of the ER membrane B transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues B involved in ER quality control B functions as a heterodimer with Pmt2p but can also pair with Pmt5p B antifungal drug target B PMT2 has a paralog C PMT3 C that arose from the whole genome duplication
108,877
110,430
-
gene
YAL022C
FUN26
FUN26,nucleoside_transmembrane_transporter_FUN26
sgd/S288C_reference_genome_R64-3-1_20210421
High affinity C broad selectivity C nucleoside/nucleobase transporter B vacuolar membrane localized transporter which may regulate the balance of nicotinamide riboside NmR levels between the cytosol and vacuole C contributing to salvage of NmR for use in cytosolic NAD+ synthesis B equilibrative nucleoside transporter ENT family member
110,846
113,359
-
gene
YAL021C
CCR4
CCR4,CCR4-NOT_core_exoribonuclease_subunit_CCR4,FUN27,NUT21
sgd/S288C_reference_genome_R64-3-1_20210421
Component of the CCR4-NOT transcriptional complex B CCR4-NOT is involved in regulation of gene expression B component of the major cytoplasmic deadenylase C which is involved in mRNA poly A tail shortening
113,614
114,615
-
gene
YAL020C
ATS1
ATS1,FUN28,KTI13
sgd/S288C_reference_genome_R64-3-1_20210421
Protein required for modification of wobble nucleosides in tRNA B acts with Elongator complex C Kti11p C and Kti12p B has a potential role in regulatory interactions between microtubules and the cell cycle B forms a stable heterodimer with Kti11p
114,250
114,819
+
gene
YAL019W-A
YAL019W-A
unknown_65
sgd/S288C_reference_genome_R64-3-1_20210421
Dubious open reading frame B unlikely to encode a functional protein C based on available experimental and comparative sequence data B partially overlaps ORF ATS1/YAL020C
114,919
118,314
+
gene
YAL019W
FUN30
FUN30,DNA-dependent_ATPase_FUN30
sgd/S288C_reference_genome_R64-3-1_20210421
Snf2p family member with ATP-dependent chromatin remodeling activity B has a role in silencing at the mating type locus C telomeres and centromeres B enriched at centromeres and is required for correct chromatin structure around centromeres C as well as at the boundary element of the silent HMR B recruited to DNA double-strand breaks DSBs where it promotes ' strand resection of DSBs B potential Cdc28p substrate
118,564
119,541
-
gene
YAL018C
LDS1
LDS1
sgd/S288C_reference_genome_R64-3-1_20210421
Protein Involved in spore wall assembly B localizes to lipid droplets found on or outside of the prospore membrane B shares similarity with Lds2p and Rrt8p C and a strain mutant for all genes exhibits reduced dityrosine fluorescence relative to the single mutants
120,225
124,295
+
gene
YAL017W
PSK1
PSK1,FUN31,serine/threonine_protein_kinase_PSK1
sgd/S288C_reference_genome_R64-3-1_20210421
PAS domain-containing serine/threonine protein kinase B coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status B PSK1 has a paralog C PSK2 C that arose from the whole genome duplication
124,307
124,492
-
gene
YAL016C-B
YAL016C-B
unknown_69
sgd/S288C_reference_genome_R64-3-1_20210421
Dubious open reading frame B unlikely to encode a functional protein C based on available experimental and comparative sequence data
124,755
125,069
-
gene
YAL016C-A
YAL016C-A
unknown_70
sgd/S288C_reference_genome_R64-3-1_20210421
Dubious open reading frame B unlikely to encode a functional protein C based on available experimental and comparative sequence data B partially overlaps ORF TPD3/YAL016W
124,879
126,786
+
gene
YAL016W
TPD3
TPD3,FUN32,protein_phosphatase_A_structural_subunit_TPD3
sgd/S288C_reference_genome_R64-3-1_20210421
Regulatory subunit A of the heterotrimeric PP2A complex B the heterotrimeric protein phosphatase A PP2A complex also contains regulatory subunit Cdc55p and either catalytic subunit Pph21p or Pph22p B required for cell morphogenesis and transcription by RNA polymerase III
126,903
128,102
-
gene
YAL015C
NTG1
NTG1,FUN33,SCR1,bifunctional_N-glycosylase/AP_lyase_NTG1,ogg2
sgd/S288C_reference_genome_R64-3-1_20210421
DNA N-glycosylase and apurinic/apyrimidinic AP lyase B involved in base excision repair B acts in both nucleus and mitochondrion B creates a double-strand break at mtDNA origins that stimulates replication in response to oxidative stress B required for maintaining mitochondrial genome integrity B NTG1 has a paralog C NTG2 C that arose from the whole genome duplication
128,252
129,019
-
gene
YAL014C
SYN8
SYN8,SLT2,UIP2,syntaxin
sgd/S288C_reference_genome_R64-3-1_20210421
Endosomal SNARE related to mammalian syntaxin
129,270
130,487
+
gene
YAL013W
DEP1
DEP1,FUN54,Rpd3L_histone_deacetylase_complex_subunit_DEP1
sgd/S288C_reference_genome_R64-3-1_20210421
Component of the Rpd3L histone deacetylase complex B required for diauxic shift-induced histone H2B deposition onto rDNA genes B transcriptional modulator involved in regulation of structural phospholipid biosynthesis genes and metabolically unrelated genes C as well as maintenance of telomeres C mating efficiency C and sporulation
130,799
131,983
+
gene
YAL012W
CYS3
CYS3,CYI1,FUN35,STR1,cystathionine_gamma-lyase_CYS3
sgd/S288C_reference_genome_R64-3-1_20210421
Cystathionine gamma-lyase B catalyzes one of the two reactions involved in the transsulfuration pathway that yields cysteine from homocysteine with the intermediary formation of cystathionine B protein abundance increases in response to DNA replication stress
132,199
134,076
+
gene
YAL011W
SWC3
SWC3,SWC1
sgd/S288C_reference_genome_R64-3-1_20210421
Protein of unknown function B component of the SWR1 complex C which exchanges histone variant H2AZ Htz1p for chromatin-bound histone H2A B required for formation of nuclear-associated array of smooth endoplasmic reticulum known as karmellae
192,337
192,417
-
gene
YAR035C-A
YAR035C-A
unknown_112
sgd/S288C_reference_genome_R64-3-1_20210421
Putative protein of unknown function B emerging ORF that arose de novo from non-genic locus B identified by gene-trapping C microarray-based expression analysis C and genome-wide homology searching B localizes to mitochondria
134,184
135,665
-
gene
YAL010C
MDM10
MDM10,FUN37
sgd/S288C_reference_genome_R64-3-1_20210421
Subunit of both the ERMES and the SAM complex B component of ERMES complex which acts as a molecular tether between the mitochondria and the ER C necessary for efficient phospholipid exchange between organelles and for mitophagy B SAM/TOB complex component that functions in the assembly of outer membrane beta-barrel proteins B involved in mitochondrial inheritance and morphology B ERMES complex is often co-localized with peroxisomes and concentrated areas of pyruvate dehydrogenase
135,854
136,633
+
gene
YAL009W
SPO7
SPO7,Nem1-Spo7_phosphatase_regulatory_subunit_SPO7
sgd/S288C_reference_genome_R64-3-1_20210421
Putative regulatory subunit of Nem1p-Spo7p phosphatase holoenzyme B regulates nuclear growth by controlling phospholipid biosynthesis C required for normal nuclear envelope morphology C premeiotic replication C and sporulation
136,914
137,510
+
gene
YAL008W
FUN14
FUN14,MCP3
sgd/S288C_reference_genome_R64-3-1_20210421
Integral mitochondrial outer membrane MOM protein B dosage suppressor of an MDM10 null that reduces ERMES-related phenotypes C such as alterations in mitochondrial morphology C protein complex assembly C and lipid profile B dosage suppressor of MDM12 C MDM34 C and MMM1 null mutant growth defects B novel mechanism of MOM import involving Tom70p C the TOM complex C and the TIM23 complex C requiring mitochondrial membrane potential and processing by the IMP complex for correct biogenesis
137,698
138,345
-
gene
YAL007C
ERP2
ERP2
sgd/S288C_reference_genome_R64-3-1_20210421
Member of the p24 family involved in ER to Golgi transport B similar to Emp24p and Erv25p B role in misfolded protein quality control B forms a heterotrimeric complex with Erp1p C Emp24p C and Erv25p B localized to COPII-coated vesicles B ERP2 has a paralog C ERP4 C that arose from the whole genome duplication
139,152
139,254
+
tRNA_gene
YNCA0002W
TRN1
TRN1,tP_UGG_A
sgd/S288C_reference_genome_R64-3-1_20210421
Proline tRNA tRNA-Pro C predicted by tRNAscan-SE analysis B target of K. lactis zymocin B can mutate to suppress +1 frameshift mutations in proline codons
139,503
141,431
-
gene
YAL005C
SSA1
SSA1,Hsp70_family_ATPase_SSA1,YG100
sgd/S288C_reference_genome_R64-3-1_20210421
ATPase involved in protein folding and NLS-directed nuclear transport B member of HSP70 family B required for ubiquitin-dependent degradation of short-lived proteins B forms chaperone complex with Ydj1p B localized to nucleus C cytoplasm C cell wall B % identical to paralog Ssa2p with different functional specificity in propagation of yeast [URE3] prions C vacuolar-mediated degradations of gluconeogenesis enzymes B general targeting factor of Hsp104p to prion fibrils
140,760
141,407
+
gene
YAL004W
YAL004W
unknown_83
sgd/S288C_reference_genome_R64-3-1_20210421
Dubious open reading frame B unlikely to encode a functional protein C based on available experimental and comparative sequence data B completely overlaps verified gene SSA1/YAL005C
142,174
143,160
+
gene
YAL003W
EFB1
EFB1,EF-1beta,TEF5,eEF1Balpha,translation_elongation_factor__subunit_beta
sgd/S288C_reference_genome_R64-3-1_20210421
Translation elongation factor beta B stimulates nucleotide exchange to regenerate EF-1 alpha-GTP for the next elongation cycle B part of the EF-1 complex C which facilitates binding of aminoacyl-tRNA to the ribosomal A site B human homolog EEF1B2 can complement yeast efb1 mutants
142,367
142,468
+
snoRNA_gene
YNCA0003W
SNR18
SNR18,snR18
sgd/S288C_reference_genome_R64-3-1_20210421
C/D box small nucleolar RNA snoRNA B commonly referred to as U18 B guides '-O-methylation of large subunit LSU rRNA at positions A649 and C650
143,707
147,531
+
gene
YAL002W
VPS8
VPS8,CORVET_complex_membrane-binding_subunit_VPS8,FUN15,VPL8,VPT8
sgd/S288C_reference_genome_R64-3-1_20210421
Membrane-binding component of the CORVET complex B involved in endosomal vesicle tethering and fusion in the endosome to vacuole protein targeting pathway B interacts with Vps21p B contains RING finger motif
147,594
151,166
-
gene
YAL001C
TFC3
TFC3,FUN24,TSV115,tau_,transcription_factor_TFIIIC_subunit_TFC3
sgd/S288C_reference_genome_R64-3-1_20210421
Subunit of RNA polymerase III transcription initiation factor complex B part of TauB domain of TFIIIC that binds DNA at BoxB promoter sites of tRNA and similar genes B cooperates with Tfc6p in DNA binding B largest of six subunits of RNA polymerase III transcription initiation factor complex TFIIIC B colocalizes with condensin at pol III genes and several ETC “extra TFIIIC ” sites B may have a role in recruiting or stabilizing Scc2/4 and condensin on chromosomes
152,257
153,876
+
gene
YAR002W
NUP60
NUP60,FG-nucleoporin_NUP60
sgd/S288C_reference_genome_R64-3-1_20210421
FG-nucleoporin component of central core of the nuclear pore complex B contributes directly to nucleocytoplasmic transport and maintenance of the nuclear pore complex NPC permeability barrier and is involved in gene tethering at the nuclear periphery B relocalizes to the cytosol in response to hypoxia B both NUP1 and NUP60 are homologous to human NUP153
154,065
154,724
-
gene
YAR002C-A
ERP1
ERP1
sgd/S288C_reference_genome_R64-3-1_20210421
Member of the p24 family involved in ER to Golgi transport B role in misfolded protein quality control B forms heterotrimeric complex with Erp2p C Emp24p C and Erv25p B localized to COPII-coated vesicles B ERP1 has a paralog C ERP6 C that arose from the whole genome duplication
155,005
156,285
+
gene
YAR003W
SWD1
SWD1,COMPASS_subunit_protein_SWD1,CPS50,FUN16,SAF49
sgd/S288C_reference_genome_R64-3-1_20210421
Subunit of the COMPASS Set1C complex B COMPASS methylates histone H3 on lysine and is required in transcriptional silencing near telomeres B WD40 beta propeller superfamily member with similarity to mammalian Rbbp7
156,754
158,619
-
gene
YAR007C
RFA1
RFA1,BUF2,FUN3,RPA1,RPA70,replication_factor_A_subunit_protein_RFA1
sgd/S288C_reference_genome_R64-3-1_20210421
Subunit of heterotrimeric Replication Protein A RPA B RPA is a highly conserved single-stranded DNA binding protein involved in DNA replication C repair C and recombination B RPA protects against inappropriate telomere recombination C and upon telomere uncapping C prevents cell proliferation by a checkpoint-independent pathway B role in DNA catenation/decatenation pathway of chromosome disentangling B relocalizes to the cytosol in response to hypoxia
192,619
196,185
+
gene
YAR042W
SWH1
SWH1,OSH1,YAR044W,oxysterol-binding_protein_related_protein_SWH1
sgd/S288C_reference_genome_R64-3-1_20210421
Protein similar to mammalian oxysterol-binding protein B contains ankyrin repeats and FFAT motif B interacts with ER anchor Scs2p at the nucleus-vacuole junction B regulated by sterol binding B SWH1 has a paralog C OSH2 C that arose from the whole genome duplication
158,966
159,793
+
gene
YAR008W
SEN34
SEN34,FUN4,tRNA_splicing_endonuclease_subunit_SEN34
sgd/S288C_reference_genome_R64-3-1_20210421
Subunit of the tRNA splicing endonuclease B tRNA splicing endonuclease Sen complex is composed of Sen2p C Sen15p C Sen34p C and Sen54p B Sen complex also cleaves the CBP1 mRNA at the mitochondrial surface B Sen34p contains the active site for tRNA ' splice site cleavage and has similarity to Sen2p and to Archaeal tRNA splicing endonuclease
160,597
164,187
-
transposable_element_gene
YAR009C
YAR009C
YARCTyB1-1,truncated_gag-pol_fusion_protein
sgd/S288C_reference_genome_R64-3-1_20210421
Retrotransposon TYA Gag and TYB Pol genes B Gag processing produces capsid proteins C Pol is cleaved to produce protease C reverse transcriptase and integrase activities B in YARCTy1-1 TYB is mutant and probably non-functional B protein product forms cytoplasmic foci upon DNA replication stress
164,544
165,866
-
transposable_element_gene
YAR010C
YAR010C
YARCTyA1-1,gag_protein
sgd/S288C_reference_genome_R64-3-1_20210421
Retrotransposon TYA Gag gene co-transcribed with TYB Pol B Gag processing produces capsid proteins B in YARCTy1-1 TYB is mutant and probably non-functional
166,267
166,339
+
tRNA_gene
YNCA0004W
TGA1
TGA1,tA_UGC_A
sgd/S288C_reference_genome_R64-3-1_20210421
Alanine tRNA tRNA-Ala C predicted by tRNAscan-SE analysis B one of nuclear tRNA genes containing the tDNA-anticodon TGC mature tRNA may be UGC or may contain modified bases C decodes GCA and probably GCG codons into alanine C one of nuclear tRNAs for alanine
166,742
168,871
-
gene
YAR014C
BUD14
BUD14,protein_phosphatase_regulator_BUD14
sgd/S288C_reference_genome_R64-3-1_20210421
Protein involved in bud-site selection B Bud14p-Glc7p complex is a cortical regulator of dynein B forms a complex with Kel1p and Kel2p that regulates Bnr1p formin to affect actin cable assembly C cytokinesis C and polarized growth B diploid mutants display a random budding pattern instead of the wild-type bipolar pattern B relative distribution to the nucleus increases upon DNA replication stress
169,375
170,295
+
gene
YAR015W
ADE1
ADE1,phosphoribosylaminoimidazolesuccinocarboxamide_synthase
sgd/S288C_reference_genome_R64-3-1_20210421
N-succinyl-5-aminoimidazole-4-carboxamide ribotide synthetase B required for 'de novo' purine nucleotide biosynthesis B red pigment accumulates in mutant cells deprived of adenine B protein abundance increases in response to DNA replication stress
170,396
171,703
-
gene
YAR018C
KIN3
KIN3,FUN52,NPK1,serine/threonine_protein_kinase_KIN3
sgd/S288C_reference_genome_R64-3-1_20210421
Nonessential serine/threonine protein kinase B possible role in DNA damage response B influences tolerance to high levels of ethanol