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Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: In summary , whilst intensive investigations are in progress to target the many HIF - 1 effectors , the results herein indicate that blocking hypoxia - inducible pathways and enhancing NK - mediated antitumor immunity by targeting HIF - 1 itself may be advantageous , especially when combined with cancer immunotherapy .
Output:
|
[
"HIF - 1"
] |
task1480-8d51113242ca495994fbd55a434fc31a
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: These cells were examined for ER mRNA by reverse transcription nested polymerase chain reaction .
Output:
|
[
"ER mRNA"
] |
task1480-e6ac3fbf61be4617beb19ad802636915
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The present study first shows that OX40 - gp34 interaction stimulates HIV - 1 expression and suggests that OX40 triggering by gp34 may play an important role in enhancing HIV - 1 production in both acutely and latently infected CD4 ( + ) T cells in vivo .
Output:
|
[
"HIV - 1"
] |
task1480-29746a636bab428dbde1b148f7115eb8
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Glucocorticoid receptor content of T lymphocytes : evidence for heterogeneity .
Output:
|
[
"Glucocorticoid receptor"
] |
task1480-d40084c3f41548dc933332214632b1e5
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: To directly examine the effect of 1 , 25 - ( OH ) 2D3 on T cell activation in the absence of other complicating interactions , we utilized a panel of cloned Ia - restricted T cell hybridomas that secrete IL 2 on activation by cloned Ia - bearing stimulator cells ( TA3 ) or when stimulated by mitogen .
Output:
|
[
"IL 2"
] |
task1480-ea7d3bb7a32247459aedc8eff30564f4
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: We have also detected a DNA - protein interaction that may be involved in the cell - type specificity of immunoglobulin expression , and we have determined that a sequence upstream of the octamer participates in an interaction with a nuclear protein ( s ) .
Output:
|
[
"nuclear protein"
] |
task1480-896abf9a12be4eebbf6f0eacd9f17fc2
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: As reactive oxygen species ( ROS ) are implicated in the signaling of lipopolysaccharide ( LPS ) , we examined whether CS has a suppressive effect on inflammatory cytokine generation from human monocyte s in vitro .
Output:
|
[
"inflammatory cytokine"
] |
task1480-0ac5df72f2fa48b98a0b4d819dbb693d
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The mechanism responsible for the delayed nuclear accumulation of phosphorylated STAT3 was examined in detail , focusing on the role of B cell - derived lymphokines .
Output:
|
[
"phosphorylated STAT3"
] |
task1480-b73c70b489344f329c518f1bbc7bb8c1
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Suppression of lung inflammation in rats by prevention of NF - kappaB activation in the liver .
Output:
|
[
"NF - kappaB"
] |
task1480-21e6a269b4094a40b4864f9ab5aa5076
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: OBJECTIVE : T lymphocytes can be activated by soluble factors such as cytokines or through direct cell - cell interactions .
Output:
|
[
"soluble factors"
] |
task1480-e1fb79a5ad144c51851da3defae4e6af
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The glucocorticoid receptor activity in normal infant thymocytes was found to be 2 , 146 + / - 726 ( s . d . ) sites per cell with dissociation constant of 1 . 4 + / - 0 . 6 X 10 ( - 8 ) M .
Output:
|
[
"glucocorticoid receptor"
] |
task1480-1e3b17c149f44c8292f9a6d1e58488da
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The ex vivo expression of I kappa B alpha was higher in PBMCs of controls than of trauma patients .
Output:
|
[
"I kappa B"
] |
task1480-7c1c2cffec8d47dea0cdc330aec6ea79
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Residues Tyr357 and Tyr462 are contained within the loop regions of adjacent helix - loop - helix - like repeats within BAP / TFII - I .
Output:
|
[
"loop regions"
] |
task1480-0a5f780563fd45e28748cdc483dbd803
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: However , in spleen cells in vitro costimulation via the TCR is necessary for optimal IL - 2 gene induction .
Output:
|
[
"IL - 2"
] |
task1480-4fcad465ed8a4996aa5f50b47d2648b2
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The resistance to cytolethal effects can not be ascribed to a failure of cells to take up and bind steroid or to significant differences in the molecular species of cytoplasmic receptors present .
Output:
|
[
"cytoplasmic receptors"
] |
task1480-69ebd0c5cbbf4fa0b0c88bddd3fcae1b
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Elevation of intracellular cAMP in T cells , induced by agents such as IL - 1alpha or PGs , inhibits T cell activation .
Output:
|
[
"IL - 1alpha"
] |
task1480-35e69bfc4df9444aa06ef211531bc74c
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Interferon - alpha drives T cell - mediated immunopathology in the intestine .
Output:
|
[
"Interferon - alpha"
] |
task1480-e769fa2c26b94743b46d6f0095f4154a
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: BAP / TFII - I , a protein implicated in transcriptional regulation , is associated with Btk in B cells and is transiently phosphorylated on tyrosine following B cell receptor engagement .
Output:
|
[
"B cell receptor"
] |
task1480-ab6f02f1af0e47e78dcddbe7f38e634b
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: In contrast , Ad5 E1A peptide injection resulted in physical deletion of preexisting Ad5 E1A - specific CTLs within 24 h after injection .
Output:
|
[
"Ad5 E1A"
] |
task1480-fd53bb8adb0b406aa6fc032d851cac4e
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: An attempt to correlate receptor levels with clinical responsiveness demonstrated that glucocorticoid receptor determination might be of value in patients with lymphoid malignancies but probably not in patients with other leukemias .
Output:
|
[
"glucocorticoid receptor"
] |
task1480-a66fdc39f3cd4f7b92faffc00c6470bb
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Mutant frequencies were measured in the spleen lymphocyte hprt gene , and lacI mutant frequencies were determined in the liver and spleen lymphocytes .
Output:
|
[
"hprt gene"
] |
task1480-e029cd42f7dd4c65add406cf206e45be
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Gadd45gamma is also dispensable for IL - 2 - induced T - cell proliferation .
Output:
|
[
"IL - 2"
] |
task1480-5a5cdc2be5cd48678d39f952528f7f6e
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: However , little is known about the effect of high glucose on MCP - 1 expression and its signal transduction pathway in human peritoneal mesothelial cells .
Output:
|
[
"MCP - 1"
] |
task1480-13f0363e0e4c4dcead828f2789ddeaf7
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: NF - kappaB activation was also inhibited by CS .
Output:
|
[
"NF - kappaB"
] |
task1480-be2e0f833241491b9676505d6d285ef1
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Monocytes are extremely important cells for regulating the cytokine network and tumor necrosis factor alpha ( TNFalpha ) and interleukin - ( IL ) 10 , which are mainly synthesized by monocytes , are representative cytokines that play a central role in the cytokine network .
Output:
|
[
"tumor necrosis factor"
] |
task1480-064a6f5c9e494393982e91f2a853e8f8
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Stat6ko Vgamma4 ( + ) cells ( IFN - gamma ( + ) ) significantly enhanced myocarditis .
Output:
|
[
"IFN - gamma"
] |
task1480-0bcd04b3db314ea490cddd0156f6e89a
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: [ Tumor histology and steroid receptors in breast carcinoma ]
Output:
|
[
"steroid receptors"
] |
task1480-de23a5e917ab41c9815b1a8f4231c48b
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Troglitazone , a PPARgamma ligand , inhibits osteopontin gene expression in human monocytes / macrophage THP - 1 cells .
Output:
|
[
"PPARgamma ligand"
] |
task1480-25d7770dc76e48158a2e81c315681808
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: These findings present major differences in the early cell activation process between LPS and muramyl peptides , and strongly argue for the implication of co - receptors other than TLR2 and TLR4 in mediating the signaling events induced by defined subunits of bacterial peptidoglycans .
Output:
|
[
"co - receptors"
] |
task1480-53a6683b9d0f404d971ccb6afac1cc22
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: This A / R - induced NF kappa B signaling response appears to be mediated , at least in part , by intracellular redox imbalance .
Output:
|
[
"NF kappa B"
] |
task1480-855418ccb4cf4d3c8015215b427edac9
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: In order to elucidate the relationship between cell water content and number of glucocorticoid receptors , eleven normal and malignant lymphoid or myelomonocytic cell types originating from mouse , rat and man were investigated .
Output:
|
[
"glucocorticoid receptors"
] |
task1480-6ae0019b465b456191a063317713e869
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The association of trans - acting T cell factors ( TCFs ) or lymphoid enhancer factor 1 ( LEF - 1 ) with their coactivator beta - catenin mediates transient transcriptional responses to extracellular Wnt signals .
Output:
|
[
"LEF - 1"
] |
task1480-80bd038389a14092a0c2d5aa7b7f54e5
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: This study expands the understanding of the role of SDF - 1 and TPO in normal human megakaryopoiesis and indicates the molecular basis of the observed differences in cellular responses .
Output:
|
[
"SDF - 1"
] |
task1480-1cbd835c0483489dad68df2f46de2d71
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Treatment of these cells with anti - IgM Abs leads to the recruitment of the kinase from cytoplasmic and nuclear compartments to the site of the cross - linked receptor at the plasma membrane .
Output:
|
[
"anti - IgM"
] |
task1480-b0e8c9cd42f047df84e822b6b100c2b8
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: TCF / LEF proteins have recently been found to constitute a downstream component of the Wingless / Wnt signal transduction pathway .
Output:
|
[
"TCF / LEF"
] |
task1480-0161082107c44c08bedf668ba2c4ebcc
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Prior transfection studies have shown that when these p65 and p50 subunits are expressed independently as stable homodimers , p65 stimulates kappa B - directed transcription , whereas p50 functions as a kappa B - specific repressor .
Output:
|
[
"stable homodimers"
] |
task1480-84d75eec23464a2eb558c6bc5e610e6e
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: B cell antigen receptor ligation resulted in enhanced tyrosine phosphorylation of STAT5 in BTK - deficient chicken B cells reconstituted with wild type human BTK but not in BTK - deficient chicken B cells reconstituted with kinase - inactive mutant BTK .
Output:
|
[
"antigen receptor"
] |
task1480-246225d0a75a49ca8bf38690edf2a62b
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: CONCLUSIONS : In both IBDs , but particularly Crohn ' s disease , increased activation of NF kappa B may be involved in the regulation of the inflammatory response .
Output:
|
[
"NF kappa B"
] |
task1480-847241b3abbd47199074f1a8583245f8
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Long - range transcriptional regulation of cytokine gene expression .
Output:
|
[
"cytokine gene"
] |
task1480-aa0133bf00b44c5ab82d72d6760b9991
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Leukemic lymphoblasts contain larger numbers of receptor sites .
Output:
|
[
"receptor sites"
] |
task1480-2a1ad1be91a44b8db9fbea5e16fccaa2
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: BACKGROUND : Eosinophils are now known to produce a variety of proinflammatory cytokines , although the molecular factors that regulate their production are poorly understood .
Output:
|
[
"proinflammatory cytokines"
] |
task1480-49662f48f1484ffd8f7c10833fbb30e7
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: This model of acute monarticular arthritis is particularly suitable for further investigations into cell - mediated immunity in arthritis and the role of IL - 1 .
Output:
|
[
"IL - 1"
] |
task1480-7086763f14e941ad8fbe79433e65788e
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The emerging theme is one of cell - type - specific regulation , affecting not only the functional activation of transcription factors but also their access to appropriate regions of DNA .
Output:
|
[
"transcription factors"
] |
task1480-407590ee3c7d4a14b24832679c665b2f
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The B cell factor was purified to homogeneity using affinity chromatography and consists of three peptides of 62 , 61 , and 58 . 5 + / - 1 . 5 kd .
Output:
|
[
"B cell factor"
] |
task1480-e191808afbfa4af09ff3aa2472928e3c
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Activated PBMCs also expressed lower levels of RXRalpha protein , and a DNA binding assay showed that the activation - induced loss of RXRalpha mRNA and protein expression correlated with the loss of DNA binding activity of this protein .
Output:
|
[
"RXRalpha mRNA"
] |
task1480-a43d0596d3fb476eb2204c5c143f5298
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: BACKGROUND : Antigen - receptor interactions on lymphocytes result in local clustering of actin , receptors and signaling molecules into an asymmetric membrane structure termed a cap .
Output:
|
[
"signaling molecules"
] |
task1480-7cea5334c8c64e2da62f8ef8b2f0d904
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Appropriate sized transcripts were detected in both cultured and fresh peripheral lymphocytes for CYP11A , CYP17 , HSD11L ( 11beta - hydroxysteroid dehydrogenase I ) , HSD17B1 ( 17beta - hydroxysteroid dehydrogenase type I ) and SRD5A1 ( 5alpha - reductase I ) .
Output:
|
[
"5alpha - reductase"
] |
task1480-59976b7b9eba4286acad15c58df18fe2
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: More than 90 % of patients with severe congenital neutropenia ( SCN ) respond to granulocyte colony - stimulating factor ( G - CSF ) therapy .
Output:
|
[
"G - CSF"
] |
task1480-2c9f27dc9a684e12b4eeec81386fed9d
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: We have previously reported that the activation of resting human immature peripheral blood T ( PBT ) lymphocytes is associated with the loss of retinoid X receptor alpha ( RXRalpha ) expression .
Output:
|
[
"retinoid X receptor"
] |
task1480-94aebf3d80394c3bb82024452f59c65d
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The decrease in the levels of RXRalpha mRNA was found to be regulated at the post - transcriptional level and involved new protein synthesis .
Output:
|
[
"RXRalpha mRNA"
] |
task1480-fa8747a438e046c1a7c0e3a54c0cc354
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The synergistic induction of tyrosine phosphorylation by H2O2 plus vanadate included physiologically relevant proteins such as PLC gamma 1 .
Output:
|
[
"PLC gamma 1"
] |
task1480-57ed9d13c7f4430b916459e0299b3ef4
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: This effect was completely reversed by preincubation with a tyrosine phosphatase inhibitor ( Na3VO4 ) , which suggests that TGF - beta1 activated a phosphatase .
Output:
|
[
"TGF - beta1"
] |
task1480-739899191b9e4f2c9b9a3ec8c45cb142
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: When these cell lines are fused , class II genes are reexpressed , indicating that immunodeficiencies in bare lymphocyte syndrome patients are the result of two distinct mutations .
Output:
|
[
"class II genes"
] |
task1480-1c8b0a1675a7459ab7c8af6beb0b5b8f
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The hypothesis of a general abnormality of the IFN - gamma transduction pathway was dismissed .
Output:
|
[
"IFN - gamma"
] |
task1480-5a6feacee6cd4d348dd97eefc12ecaed
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Although serine phosphorylation has been shown to induce ubiquitination and subsequent proteasome - mediated degradation of I kappa B - alpha , little is known about the mechanisms that lead to release of active NF - kappa B in T cells as a consequence of tyrosine phosphorylation of I kappa B - alpha [ Imbert , V . , Rupec , R . A . , Livolsi , A . , Pahl , H . L . , Traenckner , B . M . , Mueller - Dieckmann , C . , Farahifar , D . , Rossi , B . , Auberger , P . , Baeuerle , P . & Peyron , J . F . ( 1996 ) Cell 86 , 787 - - 798 ] .
Output:
|
[
"I kappa B"
] |
task1480-6bda56db0d48491c861909f7fbbd47d9
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Number of glucocorticoid receptors in lymphocytes and their sensitivity to hormone action .
Output:
|
[
"glucocorticoid receptors"
] |
task1480-d40f21fe364a4533a7502995beaeb366
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Significant proliferative responses to IRBP were elicited by 48 hours indicating that systemic priming of naive T cells to retinal antigen had occurred .
Output:
|
[
"retinal antigen"
] |
task1480-e8127ad659b84bd2a2bc5f525ca4196b
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The production of synthetic peptides containing other CTL peptide epitopes may be useful for priming CTLs in vitro and in vivo
Output:
|
[
"peptide epitopes"
] |
task1480-76e782c23680408186bd87aa2f523769
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Our results implicate an internal bipartite nuclear localizing sequence as a regulatory domain that modulates 5 - lipoxygenase redistribution and catalysis in granulocytic cells .
Output:
|
[
"5 - lipoxygenase"
] |
task1480-29b494aee05f4a9c9798620bedce716a
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: There were also significant correlations between the maximum increase in polymorphonuclear leukocytes and glucocorticoid receptor content in polymorphonuclear leukocytes ( r = 0 . 7239 , p less than 0 . 0007 ) , and between the maximum decrease in lymphocytes and glucocorticoid receptor content in lymphocytes ( r = 0 . 7703 , p less than 0 . 0002 ) .
Output:
|
[
"glucocorticoid receptor"
] |
task1480-f77ad7b5f63d41d1828d6e385cc0e0b5
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The SART3 antigen was detected in all of the breast cancer cell lines tested , 30 of 40 ( 75 % ) breast cancer tissue samples , and 0 of 3 non - tumourous breast tissue samples .
Output:
|
[
"SART3 antigen"
] |
task1480-e600d94e30c348e582aa8cbc7ba8bbed
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: METHODS : Flow cytometry , cell proliferation assays , and microscopy were used to track antigen following a single , intranasal dose of Alexa - 488 labelled retinal antigen .
Output:
|
[
"retinal antigen"
] |
task1480-061719377d2c4beebce208e9ee3e89a8
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Stimulation of primary human T - lymphocytes via CD2 and CD28 adhesion molecules induces a long - lasting proliferation ( > 3 weeks ) .
Output:
|
[
"adhesion molecules"
] |
task1480-669b34a6d1f8436885c531bd6e96f188
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The results indicate that mononuclear leukocytes could be useful for studying the physiological significance of these mineralocorticoid receptors and their regulation in humans .
Output:
|
[
"mineralocorticoid receptors"
] |
task1480-36b53dc0445a4aa89166b89aade2d714
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Current models propose that the functions of Ikaros should be disrupted by a small isoform that retains the dimerization domain and lacks the DNA - binding domain .
Output:
|
[
"dimerization domain"
] |
task1480-9e3263f33c894580a928f92147973c2b
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Positive and negative regulation of granulopoiesis by endogenous RARalpha .
Output:
|
[
"endogenous RARalpha"
] |
task1480-a4c32615231f42cd89b6ac8a4d5e5877
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: In subjects who are HDM - SPT + but IgE - , GATA - 3 expression levels remained relatively stable during culture with HDM .
Output:
|
[
"GATA - 3"
] |
task1480-a5f8c945a80e46fd8cf46b27fb924750
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Treatment of lymphocytes with cytochalasin D , which blocks actin polymerization , inhibited cap formation and produced defects in signaling and IL - 2 transcriptional induction in response to antigen - receptor signaling that were nearly identical to those seen in vav - / - cells .
Output:
|
[
"IL - 2"
] |
task1480-d0ac7ae4fa4b4adba0d58eb1a16d496f
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The Bright DNA binding domain defined a new family , which includes SWI1 , a component of the SWI . SNF complex shown to have high mobility group - like DNA binding characteristics .
Output:
|
[
"DNA binding domain"
] |
task1480-eed6fafb5de34ea59c49d5ed406011c6
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: In contrast , both T - cell - derived HD cases and cell lines were devoid of BCL - 6 mutations .
Output:
|
[
"BCL - 6"
] |
task1480-0f1f1c820bfb412ead08649b26f5bb74
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: A novel NF - kappa B complex containing p65 homodimers : implications for transcriptional control at the level of subunit dimerization .
Output:
|
[
"p65 homodimers"
] |
task1480-8022a51c46944579a77971c07c149512
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Functional correction of FA - C cells with FANCC suppresses the expression of interferon gamma - inducible genes .
Output:
|
[
"interferon gamma"
] |
task1480-88e795108ccb429ebe8b9a774d89d045
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Dendritic cells ( DCs ) are professional antigen - presenting cells which both initiate adaptive immune responses and control tolerance to self - antigens .
Output:
|
[
"self - antigens"
] |
task1480-43f172f48f7144d9ac5b96306ad5c315
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Expression of BCL - 6 protein , which is restricted to GC B cells throughout physiologic B - cell maturation , was detected in 100 % AIDS - unrelated PCNSL and in 56 . 2 % AIDS - related cases .
Output:
|
[
"BCL - 6"
] |
task1480-a045169ba3e444129f4f5c5ec327839a
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Simultaneous measurements of glucocorticoid receptor content by whole - cell assay revealed that glucocorticoid receptor content in polymorphonuclear leukocytes linearly correlated with that in the corresponding lymphocytes ( r = 0 . 9482 , p less than 0 . 0001 ) .
Output:
|
[
"glucocorticoid receptor"
] |
task1480-2bd71309802d4c2d97d3521d35987e5e
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The transcription factors Egr2 and Egr3 are potent activators of FasL expression .
Output:
|
[
"transcription factors"
] |
task1480-531f11cb5a4c41bbb9d006b805a383d6
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Investigation of mast cell responsiveness toward retinoic acid ( RA ) revealed selective promotion of ICAM - 3 expression in the human mast cell line HMC - 1 .
Output:
|
[
"ICAM - 3"
] |
task1480-94b0680ac1c742819344abb443babf03
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Similar glucocorticoid receptors can be detected in lymphoid cells from patients with acute lymphoblastic leukemia ( ALL ) .
Output:
|
[
"glucocorticoid receptors"
] |
task1480-72302c85b4864959b093c4fcb098ec95
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The covalently labeled glucocorticoid receptors were identified by polyacrylamide gel electrophoresis ( in the presence of 0 . 1 % sodium dodecyl sulfate ) .
Output:
|
[
"glucocorticoid receptors"
] |
task1480-7871755b0a824a099b03a3fe5c38cd32
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: One of the challenges in defining the molecular events regulated by Nef has been obtaining good expression of Nef protein in T cells .
Output:
|
[
"Nef protein"
] |
task1480-72ad5b78a7124cb9b660713b761b7121
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: TCF - 1 deficiency resulted in the altered usage of additional Ly - 49 receptors .
Output:
|
[
"TCF - 1"
] |
task1480-c9ea9c45e9b7417682c33e84b0016e7c
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Moreover , TH2 cells induced by culturing with autologous BMC directly inhibit EBV - CTL generation , and TH2 associated PKA , CCR3 , and STAT - 6 phosphorylation are enhanced by BMC .
Output:
|
[
"STAT - 6"
] |
task1480-a04e9a560ca3482498bd70c87244634d
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The carboxy terminus of LMP1 is also a reliable marker for individual EBV strain identification and thus offers new possibilities in tracing the molecular events leading to posttransplant lymphoproliferative disorders ( PTLDs ) .
Output:
|
[
"carboxy terminus"
] |
task1480-4b11e67225b244938ff465c140ac4fdc
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Although STAT3 also was activated by TPO , STAT3 activation remained unaltered by TGF - beta1 .
Output:
|
[
"TGF - beta1"
] |
task1480-6b57a97b71ca4cadb2fc1facc1b2c90d
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: In contrast , ablation of either Lck - binding domain abolished the ability of Tip to stimulate NF - AT - dependent transcription .
Output:
|
[
"NF - AT"
] |
task1480-b46a076f6fea4b6abe6deac7e91c0163
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: MATERIALS AND METHODS : The cells were stimulated by 100 ng / mL TPO and / or 100 ng / mL TGF - beta1 and analyzed for proliferation ( 3H thymidine incorporation ) , viability ( trypan blue exclusion ) , and protein expression and phosphorylation ( Western blot ) .
Output:
|
[
"TGF - beta1"
] |
task1480-c6b3ea3ac031478fad6037b0b4a796ba
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: To address these inconsistencies , GR protein was assessed in immune cells and tissues using cytosolic radioligand binding .
Output:
|
[
"GR protein"
] |
task1480-e6e8b4f45b47431c995f85a63b684680
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Moreover , IFN - beta could strikingly enhance the ability of CD34DCs or MoDCs to kill TRAIL - sensitive tumor cells , but LPS did not have such an effect .
Output:
|
[
"IFN - beta"
] |
task1480-36f3b64b9d07468ba3d00f605da8d06d
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: IL - 2 did not further augment phosphorylation of CREB following CD2 cross - linking .
Output:
|
[
"IL - 2"
] |
task1480-8baa6283a8654ebcb4a82ae21bbf180e
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Each of the polypeptides was renatured after SDS - PAGE and shown to bind to the octamer sequence .
Output:
|
[
"octamer sequence"
] |
task1480-233710cc7013436aa7954d185579fd93
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: gp34 is a type II transmembrane molecule belonging to the tumor necrosis factor family and is constitutively expressed on HTLV - I - producing cells but not normal resting T cells .
Output:
|
[
"tumor necrosis factor"
] |
task1480-1a0554c281fe4052a6f197ed355fea7f
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: In this study , we examined whether PPARgamma ligand regulates osteopontin gene expression in THP - 1 cells , a cell line derived from human monocytic leukemia cells which can differentiate to macrophage upon stimulation with phorbol ester PMA .
Output:
|
[
"PPARgamma ligand"
] |
task1480-c778f2a120b740b0a478a4d1aefc89c5
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Ultraviolet - B - induced DNA damage is repaired by the nucleotide excision repair mechanism very efficiently .
Output:
|
[
"- B"
] |
task1480-3a68988b3da24787a19fba73609e9e53
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The in vitro effect of G - CSF and corticosteroids on granulopoiesis was evaluated in clonogenic assays of marrow mononuclear cells , by proliferation studies of the murine myeloid cell line 32D expressing the patient ' s mutated G - CSFR , and by measuring STAT5 activation in nuclear extracts from stimulated cells .
Output:
|
[
"G - CSF"
] |
task1480-e50f4d5578df43d69d82f00412973ad2
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Human eosinophils constitutively express nuclear factor of activated T cells p and c .
Output:
|
[
"nuclear factor"
] |
task1480-650d166bbdd0452b8efca1863a1bafe4
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: It has been previously reported that IL - 2 release in activated Jurkat T requires caspase - like activity ( Posmantur et al . ( 1998 ) Exp . Cell . Res . 244 , 302 - 309 ) .
Output:
|
[
"IL - 2"
] |
task1480-c8933149f8584e64a00be131ceb3b106
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Some of the T cells had the Ia antigen and were thus probably activated .
Output:
|
[
"Ia antigen"
] |
task1480-b61d4def4c334af691a3f59ec9ac576f
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Bone resorption is regulated by the immune system , where T - cell expression of RANKL ( receptor activator of nuclear factor ( NF ) - kappaB ligand ) , a member of the tumour - necrosis factor family that is essential for osteoclastogenesis , may contribute to pathological conditions , such as autoimmune arthritis .
Output:
|
[
"nuclear factor"
] |
task1480-7dfb58f5dd8f4719881562fe0a165c89
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The glucocorticoid receptor ( GR ) quantitation by a whole - cell assay and / or cytosol technique and the in vitro sensitivity to steroids have been assessed in peripheral blood cells from normal donors and patients with chronic lymphatic leukemia ( CLL ) , acute lymphoblastic leukemia ( ALL ) , lymphosarcoma cell leukemia ( LSCL ) , acute nonlymphatic leukemia ( ANLL ) , and chronic myeloid leukemia ( CML ) .
Output:
|
[
"glucocorticoid receptor"
] |
task1480-7f246921f50a4a38af2ae5a1652e99e9
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Glucocorticoid receptor and in vitro sensitivity to steroid hormones in human lymphoproliferative diseases and myeloid leukemia .
Output:
|
[
"Glucocorticoid receptor"
] |
task1480-a0068f8f425249a691637439d082db77
|
End of preview. Expand
in Data Studio
Dataset Card for Natural Instructions (https://github.com/allenai/natural-instructions) Task: task1480_gene_extraction_jnlpba_dataset
Additional Information
Citation Information
The following paper introduces the corpus in detail. If you use the corpus in published work, please cite it:
@misc{wang2022supernaturalinstructionsgeneralizationdeclarativeinstructions,
title={Super-NaturalInstructions: Generalization via Declarative Instructions on 1600+ NLP Tasks},
author={Yizhong Wang and Swaroop Mishra and Pegah Alipoormolabashi and Yeganeh Kordi and Amirreza Mirzaei and Anjana Arunkumar and Arjun Ashok and Arut Selvan Dhanasekaran and Atharva Naik and David Stap and Eshaan Pathak and Giannis Karamanolakis and Haizhi Gary Lai and Ishan Purohit and Ishani Mondal and Jacob Anderson and Kirby Kuznia and Krima Doshi and Maitreya Patel and Kuntal Kumar Pal and Mehrad Moradshahi and Mihir Parmar and Mirali Purohit and Neeraj Varshney and Phani Rohitha Kaza and Pulkit Verma and Ravsehaj Singh Puri and Rushang Karia and Shailaja Keyur Sampat and Savan Doshi and Siddhartha Mishra and Sujan Reddy and Sumanta Patro and Tanay Dixit and Xudong Shen and Chitta Baral and Yejin Choi and Noah A. Smith and Hannaneh Hajishirzi and Daniel Khashabi},
year={2022},
eprint={2204.07705},
archivePrefix={arXiv},
primaryClass={cs.CL},
url={https://arxiv.org/abs/2204.07705},
}
More details can also be found in the following paper:
@misc{brüelgabrielsson2024compressserveservingthousands,
title={Compress then Serve: Serving Thousands of LoRA Adapters with Little Overhead},
author={Rickard Brüel-Gabrielsson and Jiacheng Zhu and Onkar Bhardwaj and Leshem Choshen and Kristjan Greenewald and Mikhail Yurochkin and Justin Solomon},
year={2024},
eprint={2407.00066},
archivePrefix={arXiv},
primaryClass={cs.DC},
url={https://arxiv.org/abs/2407.00066},
}
Contact Information
For any comments or questions, please email Rickard Brüel Gabrielsson
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