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Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Normal mouse B cells and a variety of B lymphoma cells reflective of stages of B cell differentiation ( e . g . , 70Z / 3 , CH31 , WEHI - 231 , CH12 , and J558 ) express PPAR - gamma mRNA and , by Western blot analysis , the 67 - kDa PPAR - gamma protein .
Output:
|
[
"PPAR - gamma"
] |
task1480-5ba7e88b6d81452f8c5c272c2bfe876e
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: p21ras and calcineurin synergize to regulate the nuclear factor of activated T cells .
Output:
|
[
"nuclear factor"
] |
task1480-cf8c25b64e2b4dd6b2a337066551da2d
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: We demonstrated that expression of dnEts markedly suppressed HIV - 1 infection of a T cell line .
Output:
|
[
"HIV - 1"
] |
task1480-559be5602fac43c285bf0491335e6693
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Further , we find that HEB driven by the endogenous E2A promoter can functionally replace E2A in supporting B - cell commitment and differentiation toward completion .
Output:
|
[
"endogenous E2A promoter"
] |
task1480-92cd915f0f4c4707831374981d49479b
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: A modified method for the determination of glucocorticoid receptors in human lymphocytes is suggested .
Output:
|
[
"glucocorticoid receptors"
] |
task1480-1174c44c458c4470bd5736e8e2bb4d24
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The regulation of GM - CSF expression is seen in both normal human mitogen - activated T lymphocytes and T lymphocytes from a line ( S - LB1 ) transformed with human T cell lymphotropic virus 1 ( HTLV - 1 ) .
Output:
|
[
"GM - CSF"
] |
task1480-f6459098c3ae489d872243f58bbd5a6a
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The steroid receptor content does not correlate with histological parameters
Output:
|
[
"steroid receptor"
] |
task1480-215687d3d0a6435992ea19a6f544437c
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Significant mutations were not observed in c - MYC , S14 , or alpha - fetoprotein ( AFP ) genes , but BCL - 6 was highly mutated in a large proportion of memory B cells of normal individuals .
Output:
|
[
"BCL - 6"
] |
task1480-5aaee025a6c145fbb4c5cb28158f6821
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: TRAIL / Apo2L ligand selectively induces apoptosis and overcomes drug resistance in multiple myeloma : therapeutic applications .
Output:
|
[
"TRAIL / Apo2L"
] |
task1480-6287cdf9aecf4e8a9e6e4a0a4834ad0c
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: MHC tetramers , which constitute a labeled MHC - peptide ligand suitable for binding to the Ag - specific receptor on T cells , provide a novel approach for the detection and characterization of such rare cells .
Output:
|
[
"MHC tetramers"
] |
task1480-30eddbb7718a4c58901237253e78bb92
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: A complete inhibition of DNA synthesis by dexamethasone ( Dx ) could be observed when IL 2 - depleted cultures of CTL were either incubated for 6 h with the hormone prior to the addition of IL 2 or treated simultaneously with Dx and a low concentration of IL 2 .
Output:
|
[
"IL 2"
] |
task1480-12b6802c12244f9f8c7e666eb640dfbe
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Live - attenuated human immunodeficiency virus type 1 ( HIV - 1 ) variants have shown great promise as AIDS vaccines , but continued replication can lead to the selection of faster - replicating variants that are pathogenic .
Output:
|
[
"HIV - 1"
] |
task1480-0252820bfa67491c91c75361bf0f3242
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: A detailed histopathologic review of 50 primary breast cancer tumors analyzed for estrogen receptor ( ER ) level was carried out and a variety of morphologic features correlated with ER results to identify any factors that will improve the management and prognosis for breast cancer .
Output:
|
[
"estrogen receptor"
] |
task1480-231973a51e684813836d6b3493e83d69
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Renal interstitial fibrosis is reduced in angiotensin II type 1a receptor - deficient mice .
Output:
|
[
"angiotensin II"
] |
task1480-f6345c74f2a0423699bf2b0d2d4913a8
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Most of these activities have been largely attributed to the inhibitory effect of D609 on phosphatidylcholine - specific phospholipase C .
Output:
|
[
"phospholipase C"
] |
task1480-1c288e6edf9b456895c717ee959a3010
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: In contrast , the synthetic progestins related structurally to 19 - nortestosterone , norethisterone and d - norgestrel , were virtually devoid of binding affinity towards the glucocorticoid receptor nor did they measurably influence the in vitro lymphocyte functions .
Output:
|
[
"glucocorticoid receptor"
] |
task1480-16c26168cb324a30add6cac08172fde9
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The signals regulating bcl - 6 expression are not known .
Output:
|
[
"bcl - 6"
] |
task1480-f71ebd729aec47708e50e36af9b9b05a
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The trans - activator protein Tax of human T - cell leukemia virus type I ( HTLV - I ) plays an important role in the development of adult T - cell leukemia through , at least in part , its ability to stimulate cell growth .
Output:
|
[
"trans - activator"
] |
task1480-acc85d2e6a0242d0ba930d5671efacce
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Persistent activation of the immune system is one of the hallmarks of HIV - 1 infection .
Output:
|
[
"HIV - 1"
] |
task1480-100786a101044129a2a3a6c7c9e1bfcb
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: During myelopoiesis , external differentiating signals regulate the expression of a set of transcription factors .
Output:
|
[
"transcription factors"
] |
task1480-40642479460a475d8a2949579b9a3ef8
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: As with the prototypical NF - kappa B p50 - p65 heterodimer , this novel p65 homodimeric form of NF - kappa B is functionally sequestered in the cytoplasm but rapidly appears in the nuclear compartment following cellular stimulation .
Output:
|
[
"p65 homodimeric form"
] |
task1480-dc439ea8a99c45b89316c41be0e84946
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: These Raf - responsive cell lines will be useful in elucidating the roles of the MAP kinase cascade on hematopoietic cell differentiation and malignant transformation
Output:
|
[
"MAP kinase"
] |
task1480-695da09b4ea045dd8c8378512b09263c
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: A partial glucocorticoid receptor defect may well explain the abnormal cortisol metabolism and glucocorticoid resistance commonly found in patients with anorexia nervosa .
Output:
|
[
"glucocorticoid receptor"
] |
task1480-2f31ccce80ed4e7ea3581b1aab37937f
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: However , the recent description of estrogen receptors in the thymus and in some lymphocyte subpopulations , as well as a deeper understanding of regulating factors in the immune system , open the possibility of a more detailed understanding of the estrogen mechanism of interference .
Output:
|
[
"estrogen receptors"
] |
task1480-3105ad8b3f3e462e9b5a0524fba92df3
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Molecular and cellular mediators of interleukin - 1 - dependent acute inflammatory arthritis .
Output:
|
[
"interleukin - 1"
] |
task1480-7d21204a1f3c4d4c8e28854097e99638
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Inclusion of the sequences between - 4 and + 52 enhanced promoter activity ; this was primarily because of an Sp1 recognition site at + 9 / + 15 .
Output:
|
[
"Sp1 recognition site"
] |
task1480-df745d1a4db34bc9b23bd9b414b397f4
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: To determine the presence and potential role of BCL - 6 mutations in cHD , the 5 ' - noncoding BCL - 6 proportion of single Hodgkin and Reed - Sternberg ( HRS ) cells from 6 cases of cHD and 6 cases of HD - derived cell lines was analyzed .
Output:
|
[
"BCL - 6"
] |
task1480-4b02a69ee0294635a74ee1c7ac1dd77f
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: This signaling pathway may be crucial for the control of B - cell differentiation and antibody response and has implications for the regulation of other POZ / zinc finger transcription factors in other tissues .
Output:
|
[
"transcription factors"
] |
task1480-f1c3e94062a349ee99251f9b2df020e0
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Stat4ko Vgamma4 ( + ) cells ( IL - 4 ( + ) ) neither inhibited nor enhanced disease .
Output:
|
[
"IL - 4"
] |
task1480-b79f43e239b445ee991985bc1ffb8fd0
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: PPARgamma ligands also strongly inhibited SEA - induced Vbeta3 T cell activation in vivo .
Output:
|
[
"PPARgamma ligands"
] |
task1480-8a3580e350344b6eadfd975cba8ab5a7
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Functional and physical interaction of protein - tyrosine kinases Fyn and Csk in the T - cell signaling system .
Output:
|
[
"tyrosine kinases"
] |
task1480-30fb9557da434412a0a673379c94e01e
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: At 37 degrees C the predominant form of the hormone - receptor complex was nuclear .
Output:
|
[
"receptor complex"
] |
task1480-9bd68685441d418c956de063278aa82d
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The Tip protein of Herpesvirus saimiri strain 484C binds to and activates the Lck tyrosine protein kinase .
Output:
|
[
"Tip protein"
] |
task1480-d89e765b0dd04e0d880de8de5a41168b
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: These observations directly connect the ERK MAPK cascade and HLH proteins in a linear pathway .
Output:
|
[
"HLH proteins"
] |
task1480-b343724c25cf4b3a8efb6b5f3a38db93
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Another ETS consensus sequence is located 1060 nt upstream .
Output:
|
[
"ETS consensus sequence"
] |
task1480-347d78ee7c344114a4fe4fa8b9c4f2fe
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Together , these results suggest that activated human T cells , whether lupus - derived or normal - derived , contain biologically active ERalpha proteins .
Output:
|
[
"ERalpha proteins"
] |
task1480-016adfffcbf94b2399b1819cd58bfb3d
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: To investigate the role of costimulation of OX40 in human immunodeficiency virus type 1 ( HIV - 1 ) infection by its natural ligand , gp34 , the OX40 - transfected ACH - 2 cell line , ACH - 2 / OX40 , chronically infected with HIV - 1 , was cocultured with paraformaldehyde ( PFA ) - fixed gp34 - transfected mouse cell line , SV - T2 / gp34 .
Output:
|
[
"HIV - 1"
] |
task1480-192423332e3d49d2a4d5b72b5f80e26f
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: B lymphocyte stimulator ( BLyS ) is a novel member of the TNF family of proteins expressed by myeloid cells as membrane - bound and soluble forms .
Output:
|
[
"B lymphocyte stimulator"
] |
task1480-6bd98718d4be49939911b9f4c633032a
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: We have identified a novel Kruppel - type zinc finger ( ZF ) gene , SKAT - 2 , which is selectively expressed by murine Th2 cells .
Output:
|
[
"SKAT - 2"
] |
task1480-a90167c4519e438f916f8fe12c11ae32
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Moderate - to - severe intraductal epithelial hyperplasias were more often associated with immunoglobulin G localization that were other benign lesions
Output:
|
[
"immunoglobulin G"
] |
task1480-ddd36437b6e1408faca0c1802ac46afd
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: To study B cell - specific changes that occur during the aging process , we investigated expression patterns of Pax - 5a and 5d in mature B cells of young and aged mice .
Output:
|
[
"Pax - 5a"
] |
task1480-48447f8d8f874815a1ad2d68cc36bd89
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: However , enforced expression of ICSBP failed to down - regulate IRF - 1 , ISGF3gamma , and p21 ( WAF1 ) .
Output:
|
[
"IRF - 1"
] |
task1480-8c2a870eb76b4acd887c0a6b43a81420
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: As the role of p50 remains unclear , we focused our present study on NF - kappa B1 ( p50 / p105 ) gene regulation .
Output:
|
[
"p50 / p105"
] |
task1480-5ae954648f8a4622bc5cd112305d714e
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Western blot analysis showed a 52 - kD BSAP band in B - cell lines , but not in non - B - cell or plasma cell lines .
Output:
|
[
"- B"
] |
task1480-e696d5fec1f44f59b1c13354a77302ca
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Here , we focused on the role of the PI3K - regulated serine / threonine kinase Akt - 1 in modulating macrophage survival .
Output:
|
[
"Akt - 1"
] |
task1480-1b0465720a2543a59a8868a449021ed1
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Identification and characterization of SKAT - 2 , a novel Th2 - specific zinc finger gene .
Output:
|
[
"SKAT - 2"
] |
task1480-218a41edfa4c4bf899687c6f38579260
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: There were no notable differences in the ER transcripts between patients and healthy controls .
Output:
|
[
"ER transcripts"
] |
task1480-02718bd2ecc745b48d8ba8d552d482a2
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The kinetics of TNF - alpha mRNA expression was faster , being at its peak level 1 hr after stimulation .
Output:
|
[
"TNF - alpha"
] |
task1480-8cfd8ee884a24534970e7d4f9e01e8d0
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The cytoplasmic domain of 2B4 associates with src homology 2 domain - containing protein or signaling lymphocyte activation molecule - associated protein , whose mutation is the underlying genetic defect in the X - linked lymphoproliferative syndrome .
Output:
|
[
"cytoplasmic domain"
] |
task1480-94fa566d3ca74a8fab52033fe64946d8
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Absence of the glucocorticoid receptor ( usually found in treated patients ) predicts lack of glucocorticoid responsiveness .
Output:
|
[
"glucocorticoid receptor"
] |
task1480-32ac9966893c4f99ae63168bb46f660e
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Glucocorticoid receptors are differentially expressed in the cells and tissues of the immune system .
Output:
|
[
"Glucocorticoid receptors"
] |
task1480-dd1ba518d31d4cbd83bc26ebe517b820
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Lymphocytes from patients with untreated adrenal insufficiency had fewer binding sites ( 3364 + / - 322 ) and a 2 - fold increase in binding affinity ( 5 . 4 + / - 0 . 9 mM ) .
Output:
|
[
"binding sites"
] |
task1480-2dad10ca2bd746c99a5bcaa86f26c4f0
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Since C / EBP beta was also detected in VD3 - untreated HL - 60 cells by immunoblotting , VD3 activated C / EBP beta to bind to the motif , probably through post - translational modification .
Output:
|
[
"C / EBP"
] |
task1480-4508b4cd5cdb4c0aaa28d6d5ed2ab388
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Our results imply complex regulation of expression of the gp34 gene and suggest implication of gp34 in proliferation of HTLV - I infected T cells .
Output:
|
[
"gp34 gene"
] |
task1480-f27c859a3e684a669804d0febd9c6f0e
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Finally , the use of PGs , such as 15d - PGJ ( 2 ) , and synthetic PPAR - gamma agonists to induce apoptosis in B - lineage cells may lead to the development of novel therapies for fatal B lymphomas
Output:
|
[
"PPAR - gamma"
] |
task1480-e5fd74bcd9294256bac7082bd7b56e6f
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The staining was considered to be highly specific because it could be completely blocked by preabsorption with recombinant IFN - gamma .
Output:
|
[
"IFN - gamma"
] |
task1480-a8e7b33c5e2749df95d941c5d679b56c
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: It is thus notable that the pleiotropic effects of type I IFN on CMI remain poorly understood .
Output:
|
[
"type I IFN"
] |
task1480-5516215df7914693805a99ca46e15569
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Binding of human immunodeficiency virus type 1 to CD4 and CXCR4 receptors differentially regulates expression of inflammatory genes and activates the MEK / ERK signaling pathway .
Output:
|
[
"inflammatory genes"
] |
task1480-032d0a7bb2a9494ab57efaef86db984b
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Cortisol was able to minimize the enhancement of NK cytotoxicity obtainable in the presence of immune interferon ( IFN - gamma ) .
Output:
|
[
"IFN - gamma"
] |
task1480-436380a5879b41d5b48622c68713fba4
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: CD80 induced higher levels of IL - 2 promoter - enhancer activity compared to CD86 .
Output:
|
[
"IL - 2"
] |
task1480-6275eb8451de4939ba664c1acae1c5ea
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Evidence is presented that if they are to grow , end buds must condition proximal fatty stroma by recruiting white blood cells as well as inducing stromal cell division and , possibly , estrogen receptors .
Output:
|
[
"estrogen receptors"
] |
task1480-47873d04179e4541981749014fb04851
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: CBFbeta - SMMHC preferentially inhibits the differentiation of myeloid lineage cells , while increasing the number of blastlike cells in culture .
Output:
|
[
"CBFbeta - SMMHC"
] |
task1480-0bac670dccbb438dbdb2d50d5e13465c
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Mononuclear cells infiltrating human mammary carcinomas : immunohistochemical analysis with monoclonal antibodies .
Output:
|
[
"monoclonal antibodies"
] |
task1480-c5c627d76141458f9c941e4a5ed6cd1f
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: This approach has the potential advantage of suppressing the expression of various proinflammatory Th2 cytokines simultaneously rather than suppressing the activity of a single cytokine .
Output:
|
[
"proinflammatory Th2 cytokines"
] |
task1480-318890f0f8d641eab2eed76b929d6d23
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: IFN - gamma - positive cells were present in the upper dermis of the lesions .
Output:
|
[
"IFN - gamma"
] |
task1480-e6124842398a43548479762853b5ca41
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The research described herein evaluates the expression and functional significance of peroxisome proliferator activator receptor - gamma ( PPAR - gamma ) on B - lineage cells .
Output:
|
[
"PPAR - gamma"
] |
task1480-9cead11477ed4f1593b8a8ea84202333
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: All clinical specimens from patients with lymphatic leukemia have some measurable level of glucocorticoid receptors ; therefore , the resistance seen in vivo can not be explained by the lack of receptors .
Output:
|
[
"glucocorticoid receptors"
] |
task1480-1051a5e849594f84ad25501834ffb249
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: These observations together with those from other studies indicate that formation of new glucocorticoid receptors near the S phase may be a general phenomenon in proliferating cells .
Output:
|
[
"glucocorticoid receptors"
] |
task1480-d8f291baf1f64d529ed7e5632c41021d
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Pax5 thus functions both as a transcriptional repressor and activator , depending on its interactions with corepressors of the Groucho protein family or with positive regulators such as the TATA - binding protein .
Output:
|
[
"Groucho protein family"
] |
task1480-78e71b28d74443aba42629e6be5fa5b5
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Kinetics of cytokine and NFAT gene expression in human interleukin - 2 - dependent T lymphoblasts stimulated via T - cell receptor .
Output:
|
[
"interleukin - 2"
] |
task1480-17f6ff9757754299bdb729582bb53c2e
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Kappa B - specific DNA binding proteins : role in the regulation of human interleukin - 2 gene expression .
Output:
|
[
"interleukin - 2"
] |
task1480-8ed13cf75fdc456bb74962196ffbec1e
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl - 1 expression .
Output:
|
[
"Mcl - 1"
] |
task1480-11bb2a406c49453391cbd774067a4535
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: RESULTS : Induction of NF - kappaB DNA binding by the p65 ( RelA ) / p50 heterodimer was observed in response to incubation of Mono Mac 6 cells with SF ( 20 % in culture medium ) from 5 of 8 subjects with RA , 4 of 5 with OA , and none of 3 with undifferentiated seronegative oligoarthritis .
Output:
|
[
"NF - kappaB"
] |
task1480-c266d734c373476e912306a5b35e14ed
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Glucocorticoid receptors in cytosol and nuclear extract of human leukocytes .
Output:
|
[
"Glucocorticoid receptors"
] |
task1480-d27e3027a2a2441ebafb748b79ee83c6
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Gel shift analysis , using extracts of B cells in latency or induced into the lytic cycle , identified Sp1 and Sp3 as the predominant cellular proteins bound to Rp near - 45 .
Output:
|
[
"cellular proteins"
] |
task1480-2d49f46bb6b649a185814f822b8088dc
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Binding of either factor to the octamer element occurred independently .
Output:
|
[
"octamer element"
] |
task1480-8e63b5f6aff2428686588fe0bbc9ea28
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: AIMS : To investigate whether increased activation of NF kappa B is important in IBD and may be down - regulated by anti - inflammatory treatment .
Output:
|
[
"NF kappa B"
] |
task1480-44bff16819944cd0b81c3cad3f5faedf
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Therefore , the inhibition of the IL - 12 p40 gene induction appeared to be regulated at transcriptional regulation level of the gene .
Output:
|
[
"IL - 12"
] |
task1480-dbcdaf47fc574a0facb4d303b52ac749
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Vitamin D receptor ( VDR ) concentration was quantitated in human peripheral blood mononuclear cells ( PBMC ) from patients with absorptive hypercalciuria ( AH ) and patients with high 1 , 25 ( OH ) 2D3 due to acquired or transient disease states and the results compared to those in normal subjects .
Output:
|
[
"Vitamin D receptor"
] |
task1480-978901db127347f98b771b623c32d171
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: This proliferative defect is not reversed by addition of exogenous IL - 2 and is p53 - independent .
Output:
|
[
"IL - 2"
] |
task1480-b66d2eaf53e742f492a9312ccf83331d
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Serum sex steroid and peptide hormone concentrations , and endometrial estrogen and progestin receptor levels during administration of human leukocyte interferon .
Output:
|
[
"human leukocyte interferon"
] |
task1480-d1d570e4fe1a4bcb8f7c41acbfc8b339
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Retinoic acid up - regulates myeloid ICAM - 3 expression and function in a cell - specific fashion - - evidence for retinoid signaling pathways in the mast cell lineage .
Output:
|
[
"ICAM - 3"
] |
task1480-bf4d304bb81a46a58f39bcfaf5020276
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Single dose intranasal administration of retinal autoantigen generates a rapid accumulation and cell activation in draining lymph node and spleen : implications for tolerance therapy .
Output:
|
[
"retinal autoantigen"
] |
task1480-e4d8b926dc1f4b929aefb562c25e1ea7
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Vitamin D receptor quantitation in human blood mononuclear cells in health and disease .
Output:
|
[
"Vitamin D receptor"
] |
task1480-296bc1e4a6c147fc83b13d09a4c56ee2
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Activation of FasL occurs via the NFAT - dependent induction of Egr3 , as demonstrated by the ability of exogenously provided NFATp to restore Egr - dependent FasL promoter activity in DKO lymph node cells .
Output:
|
[
"FasL promoter"
] |
task1480-9c4e145612704ae79f26524fec8ad806
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: In B - lymphoblastoid cell lines derived from two independent class II - deficient bare lymphocyte syndrome patients , we observed a drastic decrease in transcription rates of the class II genes .
Output:
|
[
"class II genes"
] |
task1480-d226cd0a542f445fb61865291d7b9d9f
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: A region of basic amino acids spanning residues 639 - 656 in the human 5 - lipoxygenase sequence resembles a consensus bipartite nuclear localizing sequence .
Output:
|
[
"5 - lipoxygenase"
] |
task1480-86ac8b78cc70454986478102d60f02be
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Inhibition of PMA - induced adhesion molecule expression and cell - cell adhesion was more pronounced when a combination of antioxidants , alpha - lipoate and alpha - tocopherol , were used compared to the use of either of these antioxidant alone .
Output:
|
[
"adhesion molecule"
] |
task1480-0bbe41021393448eb9a7d7099984e643
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Suppression of HIV type 1 replication by a dominant - negative Ets - 1 mutant .
Output:
|
[
"Ets - 1"
] |
task1480-c403b250191e45afa00729eea7ad2300
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The cytoplasmic receptors of leukaemia and lymphoblastoid lines appeared to contain both proteinaceous and phospholipid components .
Output:
|
[
"cytoplasmic receptors"
] |
task1480-3d721b7cf35844c0a33d603d5b415531
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Two sequences in the Tip protein were previously shown to be involved in binding to Lck .
Output:
|
[
"Tip protein"
] |
task1480-c9f46817bd074ccb8a8f8a3d18971e4f
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The high levels of BSAP , especially those found in large - cell lymphomas and in some follicular lymphomas , may be a consequence of deregulated gene expression and suggest a possible involvement of PAX - 5 in certain B - cell malignancies .
Output:
|
[
"PAX - 5"
] |
task1480-74131695e915400c885fd72fcdb49c5a
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Using the specific pharmacological inhibitors of PI 3 - kinase , Wortmannin and LY294002 , we demonstrate that PI 3 - kinase activity is vital for BCR - induced NF - kappaB DNA - binding activity .
Output:
|
[
"NF - kappaB"
] |
task1480-0a4d193bd09c47a2a2f2632fcc529474
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: These later findings indicate that neither homo - nor heterodimer formation is an absolute prerequisite for I kappa B alpha recognition of p65 .
Output:
|
[
"I kappa B"
] |
task1480-7d004af2a7a94d83b8ffc937b6bf4cd2
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Thus , IL - 6 promotes CD4 + Th2 differentiation and inhibits Th1 differentiation by two independent molecular mechanisms .
Output:
|
[
"IL - 6"
] |
task1480-18a937ee032a4a41831277c5a1c175a3
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Recent studies indicate that liganded PPARgamma not only promotes differentiation but also inhibits the activation of macrophages .
Output:
|
[
"liganded PPARgamma"
] |
task1480-dfe507b8c0f745eeb074750f61115e05
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Surprisingly , neither MB nor MDP were able to transduce signals via CD14 and TLR2 or 4 .
Output:
|
[
"TLR2 or 4"
] |
task1480-82f744a2113445e2b3900ce3e1095acc
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Thymocytes and T cells from IkappaBalpha ( DeltaN ) transgenic mice expressed normal levels of IL - 2R subunits .
Output:
|
[
"IL - 2R"
] |
task1480-f40206e840654887811d481000e152b9
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Primary cortisol resistance accompanied by a reduction in glucocorticoid receptors in two members of the same family .
Output:
|
[
"glucocorticoid receptors"
] |
task1480-fc9a84e1f4d64c07b6b9035606f1e66d
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Further studies show that genes governing the expression of class II antigens fall into at least three complementation groups ; two of these were previously unidentified in mutant cell lines generated in vitro .
Output:
|
[
"class II antigens"
] |
task1480-459894cfc530444e80f37c274ce0fb88
|
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