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Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: In summary , whilst intensive investigations are in progress to target the many HIF - 1 effectors , the results herein indicate that blocking hypoxia - inducible pathways and enhancing NK - mediated antitumor immunity by targeting HIF - 1 itself may be advantageous , especially when combined with cancer immunotherapy .
Output:
|
[
"HIF - 1"
] |
task1480-8d51113242ca495994fbd55a434fc31a
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: These cells were examined for ER mRNA by reverse transcription nested polymerase chain reaction .
Output:
|
[
"ER mRNA"
] |
task1480-e6ac3fbf61be4617beb19ad802636915
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The present study first shows that OX40 - gp34 interaction stimulates HIV - 1 expression and suggests that OX40 triggering by gp34 may play an important role in enhancing HIV - 1 production in both acutely and latently infected CD4 ( + ) T cells in vivo .
Output:
|
[
"HIV - 1"
] |
task1480-29746a636bab428dbde1b148f7115eb8
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Glucocorticoid receptor content of T lymphocytes : evidence for heterogeneity .
Output:
|
[
"Glucocorticoid receptor"
] |
task1480-d40084c3f41548dc933332214632b1e5
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: To directly examine the effect of 1 , 25 - ( OH ) 2D3 on T cell activation in the absence of other complicating interactions , we utilized a panel of cloned Ia - restricted T cell hybridomas that secrete IL 2 on activation by cloned Ia - bearing stimulator cells ( TA3 ) or when stimulated by mitogen .
Output:
|
[
"IL 2"
] |
task1480-ea7d3bb7a32247459aedc8eff30564f4
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: We have also detected a DNA - protein interaction that may be involved in the cell - type specificity of immunoglobulin expression , and we have determined that a sequence upstream of the octamer participates in an interaction with a nuclear protein ( s ) .
Output:
|
[
"nuclear protein"
] |
task1480-896abf9a12be4eebbf6f0eacd9f17fc2
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: As reactive oxygen species ( ROS ) are implicated in the signaling of lipopolysaccharide ( LPS ) , we examined whether CS has a suppressive effect on inflammatory cytokine generation from human monocyte s in vitro .
Output:
|
[
"inflammatory cytokine"
] |
task1480-0ac5df72f2fa48b98a0b4d819dbb693d
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The mechanism responsible for the delayed nuclear accumulation of phosphorylated STAT3 was examined in detail , focusing on the role of B cell - derived lymphokines .
Output:
|
[
"phosphorylated STAT3"
] |
task1480-b73c70b489344f329c518f1bbc7bb8c1
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Suppression of lung inflammation in rats by prevention of NF - kappaB activation in the liver .
Output:
|
[
"NF - kappaB"
] |
task1480-21e6a269b4094a40b4864f9ab5aa5076
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: OBJECTIVE : T lymphocytes can be activated by soluble factors such as cytokines or through direct cell - cell interactions .
Output:
|
[
"soluble factors"
] |
task1480-e1fb79a5ad144c51851da3defae4e6af
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The glucocorticoid receptor activity in normal infant thymocytes was found to be 2 , 146 + / - 726 ( s . d . ) sites per cell with dissociation constant of 1 . 4 + / - 0 . 6 X 10 ( - 8 ) M .
Output:
|
[
"glucocorticoid receptor"
] |
task1480-1e3b17c149f44c8292f9a6d1e58488da
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The ex vivo expression of I kappa B alpha was higher in PBMCs of controls than of trauma patients .
Output:
|
[
"I kappa B"
] |
task1480-7c1c2cffec8d47dea0cdc330aec6ea79
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Residues Tyr357 and Tyr462 are contained within the loop regions of adjacent helix - loop - helix - like repeats within BAP / TFII - I .
Output:
|
[
"loop regions"
] |
task1480-0a5f780563fd45e28748cdc483dbd803
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: However , in spleen cells in vitro costimulation via the TCR is necessary for optimal IL - 2 gene induction .
Output:
|
[
"IL - 2"
] |
task1480-4fcad465ed8a4996aa5f50b47d2648b2
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The resistance to cytolethal effects can not be ascribed to a failure of cells to take up and bind steroid or to significant differences in the molecular species of cytoplasmic receptors present .
Output:
|
[
"cytoplasmic receptors"
] |
task1480-69ebd0c5cbbf4fa0b0c88bddd3fcae1b
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Elevation of intracellular cAMP in T cells , induced by agents such as IL - 1alpha or PGs , inhibits T cell activation .
Output:
|
[
"IL - 1alpha"
] |
task1480-35e69bfc4df9444aa06ef211531bc74c
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Interferon - alpha drives T cell - mediated immunopathology in the intestine .
Output:
|
[
"Interferon - alpha"
] |
task1480-e769fa2c26b94743b46d6f0095f4154a
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: BAP / TFII - I , a protein implicated in transcriptional regulation , is associated with Btk in B cells and is transiently phosphorylated on tyrosine following B cell receptor engagement .
Output:
|
[
"B cell receptor"
] |
task1480-ab6f02f1af0e47e78dcddbe7f38e634b
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: In contrast , Ad5 E1A peptide injection resulted in physical deletion of preexisting Ad5 E1A - specific CTLs within 24 h after injection .
Output:
|
[
"Ad5 E1A"
] |
task1480-fd53bb8adb0b406aa6fc032d851cac4e
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: An attempt to correlate receptor levels with clinical responsiveness demonstrated that glucocorticoid receptor determination might be of value in patients with lymphoid malignancies but probably not in patients with other leukemias .
Output:
|
[
"glucocorticoid receptor"
] |
task1480-a66fdc39f3cd4f7b92faffc00c6470bb
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Mutant frequencies were measured in the spleen lymphocyte hprt gene , and lacI mutant frequencies were determined in the liver and spleen lymphocytes .
Output:
|
[
"hprt gene"
] |
task1480-e029cd42f7dd4c65add406cf206e45be
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Gadd45gamma is also dispensable for IL - 2 - induced T - cell proliferation .
Output:
|
[
"IL - 2"
] |
task1480-5a5cdc2be5cd48678d39f952528f7f6e
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: However , little is known about the effect of high glucose on MCP - 1 expression and its signal transduction pathway in human peritoneal mesothelial cells .
Output:
|
[
"MCP - 1"
] |
task1480-13f0363e0e4c4dcead828f2789ddeaf7
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: NF - kappaB activation was also inhibited by CS .
Output:
|
[
"NF - kappaB"
] |
task1480-be2e0f833241491b9676505d6d285ef1
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Monocytes are extremely important cells for regulating the cytokine network and tumor necrosis factor alpha ( TNFalpha ) and interleukin - ( IL ) 10 , which are mainly synthesized by monocytes , are representative cytokines that play a central role in the cytokine network .
Output:
|
[
"tumor necrosis factor"
] |
task1480-064a6f5c9e494393982e91f2a853e8f8
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Stat6ko Vgamma4 ( + ) cells ( IFN - gamma ( + ) ) significantly enhanced myocarditis .
Output:
|
[
"IFN - gamma"
] |
task1480-0bcd04b3db314ea490cddd0156f6e89a
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: [ Tumor histology and steroid receptors in breast carcinoma ]
Output:
|
[
"steroid receptors"
] |
task1480-de23a5e917ab41c9815b1a8f4231c48b
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Troglitazone , a PPARgamma ligand , inhibits osteopontin gene expression in human monocytes / macrophage THP - 1 cells .
Output:
|
[
"PPARgamma ligand"
] |
task1480-25d7770dc76e48158a2e81c315681808
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: These findings present major differences in the early cell activation process between LPS and muramyl peptides , and strongly argue for the implication of co - receptors other than TLR2 and TLR4 in mediating the signaling events induced by defined subunits of bacterial peptidoglycans .
Output:
|
[
"co - receptors"
] |
task1480-53a6683b9d0f404d971ccb6afac1cc22
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: This A / R - induced NF kappa B signaling response appears to be mediated , at least in part , by intracellular redox imbalance .
Output:
|
[
"NF kappa B"
] |
task1480-855418ccb4cf4d3c8015215b427edac9
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: In order to elucidate the relationship between cell water content and number of glucocorticoid receptors , eleven normal and malignant lymphoid or myelomonocytic cell types originating from mouse , rat and man were investigated .
Output:
|
[
"glucocorticoid receptors"
] |
task1480-6ae0019b465b456191a063317713e869
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The association of trans - acting T cell factors ( TCFs ) or lymphoid enhancer factor 1 ( LEF - 1 ) with their coactivator beta - catenin mediates transient transcriptional responses to extracellular Wnt signals .
Output:
|
[
"LEF - 1"
] |
task1480-80bd038389a14092a0c2d5aa7b7f54e5
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: This study expands the understanding of the role of SDF - 1 and TPO in normal human megakaryopoiesis and indicates the molecular basis of the observed differences in cellular responses .
Output:
|
[
"SDF - 1"
] |
task1480-1cbd835c0483489dad68df2f46de2d71
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Treatment of these cells with anti - IgM Abs leads to the recruitment of the kinase from cytoplasmic and nuclear compartments to the site of the cross - linked receptor at the plasma membrane .
Output:
|
[
"anti - IgM"
] |
task1480-b0e8c9cd42f047df84e822b6b100c2b8
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: TCF / LEF proteins have recently been found to constitute a downstream component of the Wingless / Wnt signal transduction pathway .
Output:
|
[
"TCF / LEF"
] |
task1480-0161082107c44c08bedf668ba2c4ebcc
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Prior transfection studies have shown that when these p65 and p50 subunits are expressed independently as stable homodimers , p65 stimulates kappa B - directed transcription , whereas p50 functions as a kappa B - specific repressor .
Output:
|
[
"stable homodimers"
] |
task1480-84d75eec23464a2eb558c6bc5e610e6e
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: B cell antigen receptor ligation resulted in enhanced tyrosine phosphorylation of STAT5 in BTK - deficient chicken B cells reconstituted with wild type human BTK but not in BTK - deficient chicken B cells reconstituted with kinase - inactive mutant BTK .
Output:
|
[
"antigen receptor"
] |
task1480-246225d0a75a49ca8bf38690edf2a62b
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: CONCLUSIONS : In both IBDs , but particularly Crohn ' s disease , increased activation of NF kappa B may be involved in the regulation of the inflammatory response .
Output:
|
[
"NF kappa B"
] |
task1480-847241b3abbd47199074f1a8583245f8
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Long - range transcriptional regulation of cytokine gene expression .
Output:
|
[
"cytokine gene"
] |
task1480-aa0133bf00b44c5ab82d72d6760b9991
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Leukemic lymphoblasts contain larger numbers of receptor sites .
Output:
|
[
"receptor sites"
] |
task1480-2a1ad1be91a44b8db9fbea5e16fccaa2
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: BACKGROUND : Eosinophils are now known to produce a variety of proinflammatory cytokines , although the molecular factors that regulate their production are poorly understood .
Output:
|
[
"proinflammatory cytokines"
] |
task1480-49662f48f1484ffd8f7c10833fbb30e7
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: This model of acute monarticular arthritis is particularly suitable for further investigations into cell - mediated immunity in arthritis and the role of IL - 1 .
Output:
|
[
"IL - 1"
] |
task1480-7086763f14e941ad8fbe79433e65788e
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The emerging theme is one of cell - type - specific regulation , affecting not only the functional activation of transcription factors but also their access to appropriate regions of DNA .
Output:
|
[
"transcription factors"
] |
task1480-407590ee3c7d4a14b24832679c665b2f
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The B cell factor was purified to homogeneity using affinity chromatography and consists of three peptides of 62 , 61 , and 58 . 5 + / - 1 . 5 kd .
Output:
|
[
"B cell factor"
] |
task1480-e191808afbfa4af09ff3aa2472928e3c
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Activated PBMCs also expressed lower levels of RXRalpha protein , and a DNA binding assay showed that the activation - induced loss of RXRalpha mRNA and protein expression correlated with the loss of DNA binding activity of this protein .
Output:
|
[
"RXRalpha mRNA"
] |
task1480-a43d0596d3fb476eb2204c5c143f5298
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: BACKGROUND : Antigen - receptor interactions on lymphocytes result in local clustering of actin , receptors and signaling molecules into an asymmetric membrane structure termed a cap .
Output:
|
[
"signaling molecules"
] |
task1480-7cea5334c8c64e2da62f8ef8b2f0d904
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Appropriate sized transcripts were detected in both cultured and fresh peripheral lymphocytes for CYP11A , CYP17 , HSD11L ( 11beta - hydroxysteroid dehydrogenase I ) , HSD17B1 ( 17beta - hydroxysteroid dehydrogenase type I ) and SRD5A1 ( 5alpha - reductase I ) .
Output:
|
[
"5alpha - reductase"
] |
task1480-59976b7b9eba4286acad15c58df18fe2
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: More than 90 % of patients with severe congenital neutropenia ( SCN ) respond to granulocyte colony - stimulating factor ( G - CSF ) therapy .
Output:
|
[
"G - CSF"
] |
task1480-2c9f27dc9a684e12b4eeec81386fed9d
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: We have previously reported that the activation of resting human immature peripheral blood T ( PBT ) lymphocytes is associated with the loss of retinoid X receptor alpha ( RXRalpha ) expression .
Output:
|
[
"retinoid X receptor"
] |
task1480-94aebf3d80394c3bb82024452f59c65d
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The decrease in the levels of RXRalpha mRNA was found to be regulated at the post - transcriptional level and involved new protein synthesis .
Output:
|
[
"RXRalpha mRNA"
] |
task1480-fa8747a438e046c1a7c0e3a54c0cc354
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The synergistic induction of tyrosine phosphorylation by H2O2 plus vanadate included physiologically relevant proteins such as PLC gamma 1 .
Output:
|
[
"PLC gamma 1"
] |
task1480-57ed9d13c7f4430b916459e0299b3ef4
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: This effect was completely reversed by preincubation with a tyrosine phosphatase inhibitor ( Na3VO4 ) , which suggests that TGF - beta1 activated a phosphatase .
Output:
|
[
"TGF - beta1"
] |
task1480-739899191b9e4f2c9b9a3ec8c45cb142
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: When these cell lines are fused , class II genes are reexpressed , indicating that immunodeficiencies in bare lymphocyte syndrome patients are the result of two distinct mutations .
Output:
|
[
"class II genes"
] |
task1480-1c8b0a1675a7459ab7c8af6beb0b5b8f
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The hypothesis of a general abnormality of the IFN - gamma transduction pathway was dismissed .
Output:
|
[
"IFN - gamma"
] |
task1480-5a6feacee6cd4d348dd97eefc12ecaed
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Although serine phosphorylation has been shown to induce ubiquitination and subsequent proteasome - mediated degradation of I kappa B - alpha , little is known about the mechanisms that lead to release of active NF - kappa B in T cells as a consequence of tyrosine phosphorylation of I kappa B - alpha [ Imbert , V . , Rupec , R . A . , Livolsi , A . , Pahl , H . L . , Traenckner , B . M . , Mueller - Dieckmann , C . , Farahifar , D . , Rossi , B . , Auberger , P . , Baeuerle , P . & Peyron , J . F . ( 1996 ) Cell 86 , 787 - - 798 ] .
Output:
|
[
"I kappa B"
] |
task1480-6bda56db0d48491c861909f7fbbd47d9
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Number of glucocorticoid receptors in lymphocytes and their sensitivity to hormone action .
Output:
|
[
"glucocorticoid receptors"
] |
task1480-d40f21fe364a4533a7502995beaeb366
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Significant proliferative responses to IRBP were elicited by 48 hours indicating that systemic priming of naive T cells to retinal antigen had occurred .
Output:
|
[
"retinal antigen"
] |
task1480-e8127ad659b84bd2a2bc5f525ca4196b
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The production of synthetic peptides containing other CTL peptide epitopes may be useful for priming CTLs in vitro and in vivo
Output:
|
[
"peptide epitopes"
] |
task1480-76e782c23680408186bd87aa2f523769
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Our results implicate an internal bipartite nuclear localizing sequence as a regulatory domain that modulates 5 - lipoxygenase redistribution and catalysis in granulocytic cells .
Output:
|
[
"5 - lipoxygenase"
] |
task1480-29b494aee05f4a9c9798620bedce716a
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: There were also significant correlations between the maximum increase in polymorphonuclear leukocytes and glucocorticoid receptor content in polymorphonuclear leukocytes ( r = 0 . 7239 , p less than 0 . 0007 ) , and between the maximum decrease in lymphocytes and glucocorticoid receptor content in lymphocytes ( r = 0 . 7703 , p less than 0 . 0002 ) .
Output:
|
[
"glucocorticoid receptor"
] |
task1480-f77ad7b5f63d41d1828d6e385cc0e0b5
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The SART3 antigen was detected in all of the breast cancer cell lines tested , 30 of 40 ( 75 % ) breast cancer tissue samples , and 0 of 3 non - tumourous breast tissue samples .
Output:
|
[
"SART3 antigen"
] |
task1480-e600d94e30c348e582aa8cbc7ba8bbed
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: METHODS : Flow cytometry , cell proliferation assays , and microscopy were used to track antigen following a single , intranasal dose of Alexa - 488 labelled retinal antigen .
Output:
|
[
"retinal antigen"
] |
task1480-061719377d2c4beebce208e9ee3e89a8
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Stimulation of primary human T - lymphocytes via CD2 and CD28 adhesion molecules induces a long - lasting proliferation ( > 3 weeks ) .
Output:
|
[
"adhesion molecules"
] |
task1480-669b34a6d1f8436885c531bd6e96f188
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The results indicate that mononuclear leukocytes could be useful for studying the physiological significance of these mineralocorticoid receptors and their regulation in humans .
Output:
|
[
"mineralocorticoid receptors"
] |
task1480-36b53dc0445a4aa89166b89aade2d714
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Current models propose that the functions of Ikaros should be disrupted by a small isoform that retains the dimerization domain and lacks the DNA - binding domain .
Output:
|
[
"dimerization domain"
] |
task1480-9e3263f33c894580a928f92147973c2b
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Positive and negative regulation of granulopoiesis by endogenous RARalpha .
Output:
|
[
"endogenous RARalpha"
] |
task1480-a4c32615231f42cd89b6ac8a4d5e5877
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: In subjects who are HDM - SPT + but IgE - , GATA - 3 expression levels remained relatively stable during culture with HDM .
Output:
|
[
"GATA - 3"
] |
task1480-a5f8c945a80e46fd8cf46b27fb924750
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Treatment of lymphocytes with cytochalasin D , which blocks actin polymerization , inhibited cap formation and produced defects in signaling and IL - 2 transcriptional induction in response to antigen - receptor signaling that were nearly identical to those seen in vav - / - cells .
Output:
|
[
"IL - 2"
] |
task1480-d0ac7ae4fa4b4adba0d58eb1a16d496f
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The Bright DNA binding domain defined a new family , which includes SWI1 , a component of the SWI . SNF complex shown to have high mobility group - like DNA binding characteristics .
Output:
|
[
"DNA binding domain"
] |
task1480-eed6fafb5de34ea59c49d5ed406011c6
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: In contrast , both T - cell - derived HD cases and cell lines were devoid of BCL - 6 mutations .
Output:
|
[
"BCL - 6"
] |
task1480-0f1f1c820bfb412ead08649b26f5bb74
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: A novel NF - kappa B complex containing p65 homodimers : implications for transcriptional control at the level of subunit dimerization .
Output:
|
[
"p65 homodimers"
] |
task1480-8022a51c46944579a77971c07c149512
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Functional correction of FA - C cells with FANCC suppresses the expression of interferon gamma - inducible genes .
Output:
|
[
"interferon gamma"
] |
task1480-88e795108ccb429ebe8b9a774d89d045
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Dendritic cells ( DCs ) are professional antigen - presenting cells which both initiate adaptive immune responses and control tolerance to self - antigens .
Output:
|
[
"self - antigens"
] |
task1480-43f172f48f7144d9ac5b96306ad5c315
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Expression of BCL - 6 protein , which is restricted to GC B cells throughout physiologic B - cell maturation , was detected in 100 % AIDS - unrelated PCNSL and in 56 . 2 % AIDS - related cases .
Output:
|
[
"BCL - 6"
] |
task1480-a045169ba3e444129f4f5c5ec327839a
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Simultaneous measurements of glucocorticoid receptor content by whole - cell assay revealed that glucocorticoid receptor content in polymorphonuclear leukocytes linearly correlated with that in the corresponding lymphocytes ( r = 0 . 9482 , p less than 0 . 0001 ) .
Output:
|
[
"glucocorticoid receptor"
] |
task1480-2bd71309802d4c2d97d3521d35987e5e
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The transcription factors Egr2 and Egr3 are potent activators of FasL expression .
Output:
|
[
"transcription factors"
] |
task1480-531f11cb5a4c41bbb9d006b805a383d6
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Investigation of mast cell responsiveness toward retinoic acid ( RA ) revealed selective promotion of ICAM - 3 expression in the human mast cell line HMC - 1 .
Output:
|
[
"ICAM - 3"
] |
task1480-94b0680ac1c742819344abb443babf03
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Similar glucocorticoid receptors can be detected in lymphoid cells from patients with acute lymphoblastic leukemia ( ALL ) .
Output:
|
[
"glucocorticoid receptors"
] |
task1480-72302c85b4864959b093c4fcb098ec95
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The covalently labeled glucocorticoid receptors were identified by polyacrylamide gel electrophoresis ( in the presence of 0 . 1 % sodium dodecyl sulfate ) .
Output:
|
[
"glucocorticoid receptors"
] |
task1480-7871755b0a824a099b03a3fe5c38cd32
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: One of the challenges in defining the molecular events regulated by Nef has been obtaining good expression of Nef protein in T cells .
Output:
|
[
"Nef protein"
] |
task1480-72ad5b78a7124cb9b660713b761b7121
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: TCF - 1 deficiency resulted in the altered usage of additional Ly - 49 receptors .
Output:
|
[
"TCF - 1"
] |
task1480-c9ea9c45e9b7417682c33e84b0016e7c
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Moreover , TH2 cells induced by culturing with autologous BMC directly inhibit EBV - CTL generation , and TH2 associated PKA , CCR3 , and STAT - 6 phosphorylation are enhanced by BMC .
Output:
|
[
"STAT - 6"
] |
task1480-a04e9a560ca3482498bd70c87244634d
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The carboxy terminus of LMP1 is also a reliable marker for individual EBV strain identification and thus offers new possibilities in tracing the molecular events leading to posttransplant lymphoproliferative disorders ( PTLDs ) .
Output:
|
[
"carboxy terminus"
] |
task1480-4b11e67225b244938ff465c140ac4fdc
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Although STAT3 also was activated by TPO , STAT3 activation remained unaltered by TGF - beta1 .
Output:
|
[
"TGF - beta1"
] |
task1480-6b57a97b71ca4cadb2fc1facc1b2c90d
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: In contrast , ablation of either Lck - binding domain abolished the ability of Tip to stimulate NF - AT - dependent transcription .
Output:
|
[
"NF - AT"
] |
task1480-b46a076f6fea4b6abe6deac7e91c0163
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: MATERIALS AND METHODS : The cells were stimulated by 100 ng / mL TPO and / or 100 ng / mL TGF - beta1 and analyzed for proliferation ( 3H thymidine incorporation ) , viability ( trypan blue exclusion ) , and protein expression and phosphorylation ( Western blot ) .
Output:
|
[
"TGF - beta1"
] |
task1480-c6b3ea3ac031478fad6037b0b4a796ba
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: To address these inconsistencies , GR protein was assessed in immune cells and tissues using cytosolic radioligand binding .
Output:
|
[
"GR protein"
] |
task1480-e6e8b4f45b47431c995f85a63b684680
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Moreover , IFN - beta could strikingly enhance the ability of CD34DCs or MoDCs to kill TRAIL - sensitive tumor cells , but LPS did not have such an effect .
Output:
|
[
"IFN - beta"
] |
task1480-36f3b64b9d07468ba3d00f605da8d06d
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: IL - 2 did not further augment phosphorylation of CREB following CD2 cross - linking .
Output:
|
[
"IL - 2"
] |
task1480-8baa6283a8654ebcb4a82ae21bbf180e
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Each of the polypeptides was renatured after SDS - PAGE and shown to bind to the octamer sequence .
Output:
|
[
"octamer sequence"
] |
task1480-233710cc7013436aa7954d185579fd93
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: gp34 is a type II transmembrane molecule belonging to the tumor necrosis factor family and is constitutively expressed on HTLV - I - producing cells but not normal resting T cells .
Output:
|
[
"tumor necrosis factor"
] |
task1480-1a0554c281fe4052a6f197ed355fea7f
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: In this study , we examined whether PPARgamma ligand regulates osteopontin gene expression in THP - 1 cells , a cell line derived from human monocytic leukemia cells which can differentiate to macrophage upon stimulation with phorbol ester PMA .
Output:
|
[
"PPARgamma ligand"
] |
task1480-c778f2a120b740b0a478a4d1aefc89c5
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Ultraviolet - B - induced DNA damage is repaired by the nucleotide excision repair mechanism very efficiently .
Output:
|
[
"- B"
] |
task1480-3a68988b3da24787a19fba73609e9e53
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The in vitro effect of G - CSF and corticosteroids on granulopoiesis was evaluated in clonogenic assays of marrow mononuclear cells , by proliferation studies of the murine myeloid cell line 32D expressing the patient ' s mutated G - CSFR , and by measuring STAT5 activation in nuclear extracts from stimulated cells .
Output:
|
[
"G - CSF"
] |
task1480-e50f4d5578df43d69d82f00412973ad2
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Human eosinophils constitutively express nuclear factor of activated T cells p and c .
Output:
|
[
"nuclear factor"
] |
task1480-650d166bbdd0452b8efca1863a1bafe4
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: It has been previously reported that IL - 2 release in activated Jurkat T requires caspase - like activity ( Posmantur et al . ( 1998 ) Exp . Cell . Res . 244 , 302 - 309 ) .
Output:
|
[
"IL - 2"
] |
task1480-c8933149f8584e64a00be131ceb3b106
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Some of the T cells had the Ia antigen and were thus probably activated .
Output:
|
[
"Ia antigen"
] |
task1480-b61d4def4c334af691a3f59ec9ac576f
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Bone resorption is regulated by the immune system , where T - cell expression of RANKL ( receptor activator of nuclear factor ( NF ) - kappaB ligand ) , a member of the tumour - necrosis factor family that is essential for osteoclastogenesis , may contribute to pathological conditions , such as autoimmune arthritis .
Output:
|
[
"nuclear factor"
] |
task1480-7dfb58f5dd8f4719881562fe0a165c89
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: The glucocorticoid receptor ( GR ) quantitation by a whole - cell assay and / or cytosol technique and the in vitro sensitivity to steroids have been assessed in peripheral blood cells from normal donors and patients with chronic lymphatic leukemia ( CLL ) , acute lymphoblastic leukemia ( ALL ) , lymphosarcoma cell leukemia ( LSCL ) , acute nonlymphatic leukemia ( ANLL ) , and chronic myeloid leukemia ( CML ) .
Output:
|
[
"glucocorticoid receptor"
] |
task1480-7f246921f50a4a38af2ae5a1652e99e9
|
Definition: In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
Positive Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: TCF - 1
Positive Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: NF - kappaB
Negative Example 1 -
Input: Sox - 4 is important for very early B - cell differentiation , while TCF - 1 / LEF - 1 play a crucial role in early thymocyte development
Output: development
Negative Example 2 -
Input: The NF - kappaB / Rel family represents one signal transduction pathway induced during such activation .
Output: signal
Now complete the following example -
Input: Glucocorticoid receptor and in vitro sensitivity to steroid hormones in human lymphoproliferative diseases and myeloid leukemia .
Output:
|
[
"Glucocorticoid receptor"
] |
task1480-a0068f8f425249a691637439d082db77
|
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