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https://nardus.mpn.gov.rs/handle/123456789/20754
123456789-20754.pdf
yes
no
https://fedorakg.kg.ac.rs/fedora/get/o:1520/bdef:Content/download
no
Uticaj antioksidantne suplementacije ekstraktom biljke Filipendula ulmaria na manifestacije sistemske toksičnosti nanočestica kalcijumfosfata kod pacova
[ "Selaković, Dragica" ]
[ "Rosić, Gvozden", "Vasović, Miroslav", "Bubalo, Marija" ]
Šćepanović, Radomir
2022-10-17T17:26:13
[ "2022-10-17T17:26:13" ]
2022-05-27
[ "http://eteze.kg.ac.rs/application/showtheses?thesesId=8565", "https://fedorakg.kg.ac.rs/fedora/get/o:1520/bdef:Content/download", "https://nardus.mpn.gov.rs/handle/123456789/20754" ]
[ "SAŽETAK: Uvod. Kalcijumfosfati, prirodno prisutni u ljudskom organizmu široko su prihvaćeni kao materijali izbora za regeneraciju mineralizovanih tkiva. Sve veća primena kalcijumfosfata nanoveličine, sa poznatim uticajem na oksidativni status, apoptozu, oštećenja DNK i morfofunkcionalnne promene različitih organa, nametnula je potrebu za rasvetljenem mehanizama njihove toksičnosti, kao i primene prirodnih antioksidanata, među kojima je i ekstrakt biljke Filipendula ulmaria, kao mogućim načinom prevencije iste. Materijal i metode. Istraživanje je obuhvatilo 42 mužjaka Wistar-albino pacova podeljenih u sedam jednakih grupa, tretiranih per os nano-kalcijumfosfatima (hidroksiapatit – 17.8 mg/kg tm, trikalcijum fosfat hidrat – 11 mg/kg tm i amorfni kalcijum fosfat – 9,65 mg/kg tm) samostalno, ili sa ekstraktom biljke Filipendula ulmaria (100 mg/kg tm) dnevno tokom 30 dana. Nakon žrtvovanja, određivane su vrednosti biohemijskih i hormonskih indikatora funkcije jetre, bubrega i testisa u serumu, vrednosti markera oksidativnog statusa i apoptoze, kao i histološke promene tkiva navedenih organa. Rezultati. Rezultati ove studije su pokazali da hronična sistemska primena nanokalcijumfosfata utiče na vrednosti biohemijskih parametara i serumske koncentracije polnih hormona. Istovremeno, uočeno je povećanje pro-apoptotske i pro-oksidativne aktivnosti, praćeno histološkim promenama u tkivima jetre, bubrega i testisa. Takođe, rezultati studije su potvrdili protektivni efekat antioksidantne suplementacije ekstraktom biljke Filipendula ulmaria, koji se manifestovao smanjenjem ispoljavanja sistemske toksičnosti izazvane nano-kalcijumfosfatima. Zaključak. Rezultati ove studije ukazuju na potrebu da se u budućim istraživanjima potencijalne medicinske primene materijala za nadoknadu koštanog tkiva, simultano uključi i sistematska procena toksičnosti. Takođe, potvrđeno je da primena antioksidantne suplementacije može biti korisna u prevenciji sistemske toksičnosti izazvane različitim formama nano-kalcijumfosfata." ]
[ "ABSTRACT: Introduction. Calcium phosphates that naturally appear in human body are broadly accepted as the first choice materials for regeneration of mineralized tissues. A growing employement of nano-sized calcium phosphates, with confirmed impact on oxidative status, apoptosis, DNA damage, and morphofunctional alterations in various organs, implied the necessity for enlightning mechanisms of their toxicity, as well as the usage of natural antioxidants, including the Filipendula ulmaria extract, as a potential prevention. Materials and methods. Forty two male Wistar-albino rats, divided into seven equal groups, per os treated with nano-sized calcium phosphates (hydroxyapatite - 17.8 mg/kg b.w., tricalcium phosphate hydrate – 11 mg/kg b.w. and amorphous calcium phosphate – 9.65 mg/kg b.w.) alone, or with the Filipendula ulmaria extract (100 mg / kg b.w.) daily for 30 days. After sacrificing, the values of biochemical and hormonal indicators for liver, kidney, and testes were determined in sera samples, as well as the oxidative stress and apoptotic markers, and histological alterations in those organs. Results. The results of this study showed that chronic systemic administration of nano-sized calcium phosphates influenced the biochemical parameters and serum hormone levels. At the same time, it has been observed that increased pro-apoptotic and pro-oxidant activity were accompanied with histological alterations in liver, kidney, and testicle tissues. Also, the results of this study confirmed the protective role of antioxidant supplementation with Filipendula ulmaria extract that was manifested by attenuation of nano-sized calciumphosphates-induced toxicities, Conclusion. The results of this study imply the necessity that simulataneous evaluation of systemic toxicities shoul be included in the future investigations of materials for potential medical replacement of bone tissue. Also, it has been confirmed that antioxidant supplementation may be beneficial in the prevention of systemic toxicities induced by various forms of nano-sized calcium phosphates." ]
application/pdf
sr
Универзитет у Крагујевцу, Факултет медицинских наука
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Крагујевцу
[ "nano-kalcijumfosfati", "Filipendula ulmaria", "sistemska toksičnost", "polni hormoni", "oksidativni stres", "apoptoza", "jetra", "bubreg", "testis" ]
[ "nano-sized calcium phosphates", "Filipendula ulmaria", "systemic toxicity", "sex hormones", "oxidative stress", "apoptosis", "liver", "kidney", "testis" ]
[ "Uticaj antioksidantne suplementacije ekstraktom biljke Filipendula ulmaria na manifestacije sistemske toksičnosti nanočestica kalcijumfosfata kod pacova" ]
[ "" ]
doctoralThesis
[ "BY-NC-ND" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/146449/Izvestaj_Radomir_Scepanovic_Medicina.pdf", "http://nardus.mpn.gov.rs/bitstream/id/146448/Doctoral_thesis_12630.pdf", "https://fedorakg.kg.ac.rs/fedora/get/o:1520/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_20754" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/21549
123456789-21549.pdf
yes
no
https://fedorabg.bg.ac.rs/fedora/get/o:30682/bdef:Content/download
no
Cross-talk of insulin, leptin and glucocorticoid signaling in the rat hypothalamus and skeletal muscle during metabolic disturbances induced by dietary fructose and stress
Interakcije signalnih puteva insulina, leptina i glukokortikoida u hipotalamusu i skeletnom mišiću pacova tokom metaboličkih poremećaja izazvanih ishranom obogaćenom fruktozom i stresom
[ "Kovačević, Sanja" ]
[ "Vujović, Predrag", "Đorđević, Ana", "Savić-Pavićević, Dušanka", "Kojić, Snežana" ]
Shirif, Abdulbaset
2023-09-06T10:58:37
[ "2023-09-06T10:58:37" ]
2023-05-30
[ "https://uvidok.rcub.bg.ac.rs/bitstream/handle/123456789/5158/Referat.pdf", "https://eteze.bg.ac.rs/application/showtheses?thesesId=9231", "https://fedorabg.bg.ac.rs/fedora/get/o:30682/bdef:Content/download", "https://plus.cobiss.net/cobiss/sr/sr/bib/121662729", "https://nardus.mpn.gov.rs/handle/123456789/21549" ]
[ "Modern way of living includes unpredictable stressful daily events and consumption of caloric fructose-rich food. Increased incidence of insulin resistance and metabolic syndrome raise the necessity to investigate how these two factors present in our everyday lives influence metabolic health. The aim of this doctoral dissertation is to test the hypothesis that fructose diet combined with chronic unpredictable stress induces more pronounced metabolic derangements in the skeletal muscle and hypothalamus of male Wistar rats than each of the factors applied separately. With that in mind, we analyzed hypothalamic insulin and leptin signaling and their effects on appetite regulation, skeletal muscle insulin signaling, and lipid metabolism, muscle glucocorticoid signaling and inflammation after challenging conditions of excessive fructose consumption (9 weeks) and/or exposure to chronic unpredictable stress (4 weeks). Results showed that fructose diet combined with chronic stress altered expression of hypothalamic neuropeptides causing increased appetite and energy intake, increased activity of AMPK energy sensor and impaired insulin signaling. In the skeletal muscle, combination of fructose and stress caused muscle lipid overload and disturbed lipid metabolism by increasing lipolysis and β-oxidation. Decreased muscle glucocorticoid signaling enabled rise of uncontrolled lipid-induced inflammation creating a setting for muscle insulin signaling impairment detected after combination of the treatments. Results of this doctoral dissertation have clearly showed that combination of fructose diet and chronic stress exposure had more detrimental effects on the hypothalamus and skeletal muscle of male rats than each of the treatments applied separately." ]
[ "Moderan način života se sastoji od svakodnevnih nepredvidivih stresnih događaja i konzumiranja kalorične hrane bogate fruktozom. Povećana učestalost insulinske rezistencije i metaboličkog sindroma nameće potrebu da se istraži kako ova dva faktora prisutna u našem svakodnevnom životu utiču na metaboličko zdravlje. Cilj ove doktorske disertacije je da se ispita hipoteza da ishrana bogata fruktozom u kombinaciji sa hroničnim nepredvidivim stresom izaziva izraženije metaboličke poremećaje u skeletnim mišićima i hipotalamusu mužjaka pacova nego svaki od primenjenih tretmana ponaosob. Imajući to na umu, analizirali smo signalizaciju insulina i leptina u hipotalamusu i njihove efekte na regulaciju apetita, signalizaciju insulina u skeletnim mišićima, metabolizam lipida, signalizaciju glukokortikoida i inflamaciju nakon prekomernog unosa fruktoze (9 nedelja) i/ili izloženosti hroničnom nepredvidivom stresu (4 nedelje). Rezultati su pokazali da ishrana bogata fruktozom u kombinaciji sa hroničnim stresom menja ekspresiju neuropeptida hipotalamusa, izazivajući povećan apetit i unos energije, povećanu aktivnost energetskog senzora AMPK i narušava insulinsku signalizaciju. U skeletnim mišićima, kombinacija fruktoze i stresa izazvala je povećanje unosa lipida i nivoa lipolize i β-oksidacije. Inhibirana glukokortikoidna signalizacija omogućava povećanje nekontrolisane inflamacije izazvane lipidima, doprinoseći poremećaju mišićne insulinske signalizacije nakon kombinacije tretmana. Rezultati ove doktorske disertacije jasno su pokazali da je kombinacija ishrane bogate fruktozom i hronične izloženosti stresu izazvala štenije efekte na hipotalamus i skeletne mišiće mužjaka pacova nego svaki od tretmana primenjen pojedinačno." ]
application/pdf
sr
Универзитет у Београду, Биолошки факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-sa/4.0/" ]
Универзитет у Београду
[ "Chronic stress", "fructose", "skeletal muscle", "hypothalamus", "glucocorticoid hormones", "leptin", "lipid metabolism", "insulin resistance", "inflammation" ]
[ "Hronični stres", "fruktoza", "skeletni mišići", "hipotalamus", "glukokortikoidni hormoni", "lipidni metabolizam", "insulinska rezistencija, inflamacija" ]
[ "Cross-talk of insulin, leptin and glucocorticoid signaling in the rat hypothalamus and skeletal muscle during metabolic disturbances induced by dietary fructose and stress" ]
[ "Interakcije signalnih puteva insulina, leptina i glukokortikoida u hipotalamusu i skeletnom mišiću pacova tokom metaboličkih poremećaja izazvanih ishranom obogaćenom fruktozom i stresom" ]
doctoralThesis
[ "BY-NC-SA" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/151566/Disertacija_13692.pdf", "http://nardus.mpn.gov.rs/bitstream/id/152460/Referat.pdf", "https://fedorabg.bg.ac.rs/fedora/get/o:30682/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_21549" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/21572
123456789-21572.pdf
yes
no
https://fedorabg.bg.ac.rs/fedora/get/o:30599/bdef:Content/download
no
Mentalno zdravlje neformalnih negovatelja tokom epidemije Kovid-19 u Srbiji:: modelovanje strukturalnim jednačinama
Mental health of informal caregivers during the Covid-19 epidemic in Serbia: a path analysis
[ "Milić, Nataša" ]
[ "Stanisavljević, Dejana", "Matejić, Bojana", "Mašić, Srđan" ]
Rajović, Tatjana
2023-09-06T11:01:07
[ "2023-09-06T11:01:07" ]
2023-04-11
[ "https://uvidok.rcub.bg.ac.rs/bitstream/handle/123456789/5116/Referat.pdf", "https://eteze.bg.ac.rs/application/showtheses?thesesId=9205", "https://fedorabg.bg.ac.rs/fedora/get/o:30599/bdef:Content/download", "https://plus.cobiss.net/cobiss/sr/sr/bib/121763337", "https://nardus.mpn.gov.rs/handle/123456789/21572" ]
[ "VOD: Cilj ove studije bio je ispitivanje kompleksnih odnosa između višestrukih determinanti procesa nege, opterećenja i depresije negovatelja tokom epidemije Kovid-19 u Srbiji. METODE: Istraživanje po tipu studije preseka sprovedeno je na nacionalno reprezentativnom uzorku (n=798) tokom epidemije Kovid-19 u Srbiji, od marta do septembra 2020. godine. Upitnik dizajniran za ovu studiju sastojao se od devet delova i uključivao je socio-demografske karakteristike neformalnih negovatelja, karakteristike negovanih osoba i nege, pitanja vezana za pružanje nege u novonastalim okolnostima tokom Kovid-19 epidemije i sledeće standardizovane instrumente: kratka forma upitnika za procenu kvaliteta života povezanog sa zdravljem SF-12, Krupova skala zamora, skala za ispitivanje bazičnih i instrumentalnih aktivnosti svakodnevnog života, Zarit Intervju za procenu opterećenja neformalnih negovatelja i Bekova skala depresivnosti. Modelovanje strukturalnim jednačinama korišćeno je za istovremenu procenu direktnih i indirektnih odnosa svih determinanti. REZULTATI: Više od dve trećine (71,9%) neformalnih negovatelja bilo je pod opterećenjem, a više od jedne četvrtine (27,1%) osećalo se depresivno. Samoprocenjeno fizičko zdravlje, potreba za psihosocijalnom podrškom i opterećenje negovatelja bili su glavni direktni prediktori depresije. Višestruke determinante nege imale su indirektne efekte na nastanak depresije, sa opterećenjem negovatelja kao posredničkim faktorom. ZAKLJUČCI: Subjektivno opterećenje predstavljalo je značajan faktor rizika za nastanak depresije kod neformalnih negovatelja tokom epidemije Kovid-19. Pružanje psihosocijalne podrške je prepoznato kao važna prilika za smanjenje rizika od depresije kod neformalnih negovatelja." ]
[ "BACKGROUND: The objective of this study was to assess the complex relationship between the multiple determinants of the caregiving process, the caregiver burden, and depression during the COVID-19 epidemic in Serbia. METHODS: A cross-sectional study was conducted on a nationally representative sample (n=798) during the COVID-19 epidemic in Serbia from March to September 2020. A nine- section questionnaire designed for this study included the characteristics of caregivers, characteristics of care and care recipients, COVID-19 related questions, and the following standardized instruments: 12-Item Short-Form Health Survey, Fatigue Severity Scale, Activities of Daily Living Scale and Instrumental Activities of Daily Living Scale, Zarit Caregiver Burden Scale, and Beck Depression Inventory. Path analysis was used for the simultaneous assessment of the direct and indirect relationships of all determinants. RESULTS: More than two thirds (71.9%) of informal caregivers experienced a burden, and more than one quarter (27.1%) had depression symptomatology. Self-rated physical health, need for psychosocial support, and caregiver burden were the main direct predictors of depression. Multiple determinants of the caregiving process had indirect effects on depressive symptomatology via the caregiver burden as a mediating factor. CONCLUSIONS: The subjective burden presented a significant risk factor for depressive symptoms in caregivers during the COVID-19 epidemic in Serbia. The provision of psychosocial support was identified as an important opportunity to reduce depressive risk in informal caregivers." ]
application/pdf
sr
Универзитет у Београду, Медицински факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Београду
[ "neformalni negovatelj", "Kovid-19", "opterećenje", "depresija", "psihosocijalna podrška", "mentalno zdravlje" ]
[ "informal caregiver", "the COVID-19", "burden", "depression", "psychosocial support", "mental health" ]
[ "Mentalno zdravlje neformalnih negovatelja tokom epidemije Kovid-19 u Srbiji:: modelovanje strukturalnim jednačinama" ]
[ "Mental health of informal caregivers during the Covid-19 epidemic in Serbia: a path analysis" ]
doctoralThesis
[ "BY-NC-ND" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/151634/Disertacija_13666.pdf", "http://nardus.mpn.gov.rs/bitstream/id/152465/Referat.pdf", "https://fedorabg.bg.ac.rs/fedora/get/o:30599/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_21572" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/21578
123456789-21578.pdf
yes
no
https://fedorabg.bg.ac.rs/fedora/get/o:30572/bdef:Content/download
no
Uticaj različitih kulinarskih metoda na parametre oralnog procesiranja hrane
Influence of different cooking methods on food oral processing parameters
[ "Đekić, Ilija" ]
[ "Tomašević, Igor", "Tomić, Nikola S.", "Tomović, Vladimir M.", "Pešić, Mirjana B." ]
Ilić, Jovan
2023-09-06T11:02:01
[ "2023-09-06T11:02:01" ]
2023-03-09
[ "https://uvidok.rcub.bg.ac.rs/bitstream/handle/123456789/5079/Referat.pdf", "https://eteze.bg.ac.rs/application/showtheses?thesesId=9199", "https://fedorabg.bg.ac.rs/fedora/get/o:30572/bdef:Content/download", "https://plus.cobiss.net/cobiss/sr/sr/bib/121582089", "https://nardus.mpn.gov.rs/handle/123456789/21578" ]
[ "Kuvanje u ključaloj vodi, na pari, grilovanje i sous-vide su bili primenjeni za pripremu uzoraka mesa domaće i divlje svinje, celera, krompira, tikvica i plavog patlidžana. Ciljevi istraživanja su bili utvrđivanje njihovog uticaja na mehaničke, pojavne, senzorne i karakteristike oralnog procesiranja. Dodatno je konstruisan i model kuće kvaliteta. U slučaju intenzivnijih tretmana kuvanja mesa došlo je do povećanja parametara instrumentalne teksture tvrdoće i žvakljivosti. Ovo je takođe prouzrokovalo smanjenje crvene boje i povećanje napora mastikacije. Bolusi tvrđeg mesa imali su više malih čestica i veći sadržaj salive. Tvrđe meso je bilo percipirano kao suvo i fibrozno. U slučaju povrća, intenzivniji tretmani su proizveli suprotan trend – došlo je do omekšavanja i trebalo je manje napora za mastikaciju. Promene bolusa kod povrća su pokazale sličan trend kao i kod mesa, gledajući njihovu veličinu i broj. Inkorporacija salive je ukazala na kompleksnost oralne destrukcije. Primenjeni model kvaliteta je rezultovao ocenama indeksa lakoće žvakanja. Prema ovome meso je bilo najzahtevnije za mastikaciju, posebno meso kuvano u vodi. Povrće je imalo veće ocene, posebno kuvano u vodi i na pari." ]
[ "Influence of different cooking methods on food oral processing parameters ABSTRACT Boiling, Steaming, grilling, and sous-vide cooking were used to prepare samples of pork and wild boar meat, celeriac, potato, zucchini, and eggplant. This research aimed to explore cooking influence on mechanical, oral processing, sensory properties, and appearance. Additionally, a house of quality model was constructed. In the case of more intensive meat cooking, instrumental harness and chewiness values increased. That also caused a decrease in the red color and increased the mastication effort. The boluses from harder meat had more small particles and incorporated more saliva. Hard meat was seen as dry and fibrous. In the case of the vegetables, more intensive treatments caused an opposite trend – the softening occurred, and less mastication effort was needed. Changes in the vegetables’ boluses showed a similar trend as meat, looking at their number and size. Saliva incorporation indicated the complexity of the in-oral destruction. A quality model that was applied resulted in ease of mastication index values. According to it, meat was the most demanding for mastication, especially when boiled. The vegetables had higher scores, especially when boiled and steamed." ]
application/pdf
sr
Универзитет у Београду, Пољопривредни факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Београду
[ "kuvanje u ključaloj vodi", "kuvanje na pari", "grilovanje", "sous-vide", "meso", "povrće", "mastikacija", "bolus", "dinamički senzorni profil", "modelovanje kvaliteta" ]
[ "boiling", "steaming, grilling", "sous-vide", "meat", "vegetables", "mastication", "bolus", "dynamic sensory profile", "quality modelling" ]
[ "Uticaj različitih kulinarskih metoda na parametre oralnog procesiranja hrane" ]
[ "Influence of different cooking methods on food oral processing parameters" ]
doctoralThesis
[ "BY-NC-ND" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/151652/Disertacija_13660.pdf", "http://nardus.mpn.gov.rs/bitstream/id/152472/Referat.pdf", "https://fedorabg.bg.ac.rs/fedora/get/o:30572/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_21578" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/9389
123456789-9389.pdf
yes
no
https://fedorakg.kg.ac.rs/fedora/get/o:956/bdef:Content/download
no
Slika - žanr srpske realističke proze
Image – a Genre of Serbian Realistic Prose
[ "Ivanić, Dušan" ]
[ "Vukićević, Dragana", "Milosavljević Milić, Snežana M.", "Bošković, Dragan" ]
Živković, Ana S.
2018-04-23T10:45:39
[ "2018-04-23T10:45:39", "2020-07-03T15:23:55" ]
2018-03-09
[ "http://eteze.kg.ac.rs/application/showtheses?thesesId=5724", "https://nardus.mpn.gov.rs/handle/123456789/9389", "https://fedorakg.kg.ac.rs/fedora/get/o:956/bdef:Content/download" ]
[ "U radu Slika – žanr srpske realističke proze sagledavaju se tematski i strukturalni aspekti žanra slike u književnosti srpskog realizma. Primenom istorijske, strukturalističke, marksističke i poststrukturalističke metodologije ispituju se načini uvođenja društvenih, ideoloških i istorijskih oblika mišljenja u strukture književnih dela, koja su objavljivana u periodu od 1860. godine do kraja 19. veka (Jakov Ignjatović, Milorad Popović Šapčanin, Đura Jakšić, Milan Đ. Milićević, Janko Veselinović, Ilija Vukićević, Svetolik Ranković, Simo Matavulj, Stevan Sremac, Radoje Domanović). Kako do danas nije napisana obuhvatna studija, kojom bi bio određen pojam žanra slike, literarno, socijalno i političko poreklo, te evolucija i komparativistički aspekti ovog žanrovskog modela otvaraju mogućnosti za tumačenje ne samo razvoja realističkog žanrovskog sistema već srpske literature u celini. Osim ograničenja nacionalnim, žanrovskim i hronološkim kriterijumom, predmet istraživanja određen je i tematskim aspektom odabranih tekstova, što uslovljava razvrstavanje žanra slike na zasebne podvrste (slike iz seoskog života, slike iz rata, slike iz istorije, slike iz učiteljskog života, slike iz lova, slike iz gradskog života i dr.). U radu Slika – žanr srpske realističke proze osobito će biti ispitani morfološki, narativni i retorički aspekti žanra slike: vrednost formalnih rešenja, žanrovska prožimanja, pripovedne strategije, sličnost strukturne organizacije sa delima likovne umetnosti, različitost u odnosu na srodne pripovedne oblike, uloga čitalačke publike, pomeranje ka virtuelizaciji naracije, učešće parodijskih sredstava. Ideološkom kritičkom orijentacijom obuhvatiće se: ukrštaj dokumentarnog i fikcionalnog, književni i neknjiževni kontekst, upliv ideoloških činilaca. Ključna strukturalna obeležja obuhvataju postupak „okvira‖, tehniku „skaza‖, hronotop puta, jedan događaj i jednog junaka, portret, opise eksterijera i enterijera, vizuelne jedinice u naraciji. Analitičkim i sintetičkim pristupom, stiče se uverenje da slika estetskim sredstvima zamagljuje obezličenje sveta i pokušava da reafirmiše subjektivizovani i psihologizovani svet, odnosno energiju opažanja i percepciju kao samostalne ljudske delatnosti. Realistički žanr slike očituje stilističku proizvodnju kao strategiju estetizovanja, dok tematska podela unutar opisanog žanrovskog polja raskriva potisnutu podvojenost istorijskog sveta. Uvidom u modalitete strukturisanja jezika u žanru kao što je slika, u načine izrastanja formi smisla koje se projavljuju u okvirima slike, raspoznajemo i integralno značenje jezika, njegovu stvaralačku angažovanost koliko u postizanju estetskog kvaliteta kao takvog, toliko i u opstajanju svesti humaniteta o sebi." ]
[ "The work Image – a Genre of Serbian Realistic Prose, examines thematic and structural aspects of the genre image in the literature of the Serbian realism. It also examines the ways of introducing social, ideological and historical forms of thinking into the structure of literary works, published in the period from 1860 to the end of 19th century, by the application of historical, structuralistic, marxistic, and post-structuralistic methodologies – in regard to authors such as Jakov Ignjatović, Milorad Popović Šapčanin, Đura Jakšić, Janko Veselinović, Ilija Vukićević, Svetolik Ranković, Simo Matavulj, Stevan Sremac, Radoje Domanović. Until present it was not yet written a comprehensive study that would define the notion of genre images, its literary, social and political origins, as well as evolutionary and comparative aspects of this genre pattern, opening up the possibilities for interpreting not only the development of realistic genre system but also the Serbian literature as a whole. Beyond the limitations by national, genre and chronological criteria, this study subject is defined by thematic aspects of selected works conditioning determining the division of the genre images into separate sub-species (images of rural life, war, teacher’s life, from history, hunt, city life, etc.). This studyof the work Image – a Genre of Serbian Realistic Prose will particularly examine the morphological, narrative and rhetorical aspects of the genre: the value of formal solutions, genre permeation, narrative strategies, similarity of the structural organization with fine arts works, the difference in relation to related narrative forms, the role of the reading audience, the shift towards the visualization of the narration, and participation of the parody means. The ideological critique orientation will encompass: crossing documentary and fictional, literary and non-literary context, and influence of ideological factors. Key structural features include the frame procedure, the depiction technique, the chrono-tope path, one event and one hero, portrait, exterior and interior descriptions, and visual units in the narration. Applying the analytical and synthetic approach we can witness one concept that picture by its aesthetic means blurs defilement of the world and attempts to reaffirm the subjective and psychologized world, that is, the energy of perception and perception as an independent human activities. The realistic genre image reveals a stylistic production as a strategy of anesthetisation, while the thematic division within the described genre field opens the suppressed dualism of the historical world. Inspecting the modalities of the language structure in the genre image, the ways of the maturing the forms of sense that are being propagated within the image frames, we can recognize the integral meaning of the language, its creative engagement in achieving aestheticquality as such, and the same in the survival of the consciousness of humanity about oneself." ]
application/pdf
sr
Универзитет у Крагујевцу, Филолошко-уметнички факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc/4.0/" ]
Универзитет у Крагујевцу
[ "žanr slike", "srpski realizam", "istorijska poetika", "mimezis", "forma", "struktura", "evolucija", "jezik", "skaz", "naracija", "deskripcija", "estetizacija" ]
[ "genre image", "Serbian realism", "historical methodology", "mimesis", "form", "structure", "evolution", "language", "depiction technique", "narration", "description", "esthetization" ]
[ "Slika - žanr srpske realističke proze" ]
[ "Image – a Genre of Serbian Realistic Prose" ]
doctoralThesis
[ "BY-NC" ]
Иванић, Душан; Милосављевић Милић, Снежана М.; Вукићевић, Драгана; Бошковић, Драган; Живковић, Aна С.; Слика - жанр српске реалистичке прозе; Слика - жанр српске реалистичке прозе;
[ "http://nardus.mpn.gov.rs/bitstream/id/50910/Disertacija.pdf", "http://nardus.mpn.gov.rs/bitstream/id/50911/Izvestaj_o_uradjenoj_doktorskoj_disertaciji_kandidata_Ane_Zivkovic.pdf", "https://nardus.mpn.gov.rs/bitstream/id/50911/Izvestaj_o_uradjenoj_doktorskoj_disertaciji_kandidata_Ane_Zivkovic.pdf", "https://nardus.mpn.gov.rs/bitstream/id/50910/Disertacija.pdf", "https://fedorakg.kg.ac.rs/fedora/get/o:956/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_9389" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
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https://nardus.mpn.gov.rs/handle/123456789/3843
123456789-3843.pdf
yes
no
https://fedorakg.kg.ac.rs/fedora/get/o:499/bdef:Content/download
no
Utopijsko-mitološko-istorijski diskurs Borislava Pekića i Džulijana Barnsa
Utopian, Mythological and Historical Discourse of Borislav Pekić and Julian Barnes
[ "Bošković, Dragan" ]
[ "Nastić, Radmila", "Đorić, Biljana", "Bubanja, Nikola" ]
Teodorović, Jasmina
2016-01-05T13:17:42
[ "2016-01-05T13:17:42", "2020-07-03T15:23:19" ]
2015-10-01
[ "http://eteze.kg.ac.rs/application/showtheses?thesesId=2067", "https://nardus.mpn.gov.rs/handle/123456789/3843", "https://fedorakg.kg.ac.rs/fedora/get/o:499/bdef:Content/download" ]
[ "disertaciji Utopijsko-mitološko-istorijski diskurs Borislava Pekića i Džulijana Barnsa iz stvaralaštva oba pisca, za predmet naše analize izdvajamo Argonautiku, Atlantidu i Novi Jerusalim Borislava Pekića, odnosno Istoriju sveta u 10 ½ poglavlja, Nije to ništa strašno i Puls Džulijana Barnsa. U uvodnom delu rada razrađuju se pojmovi utopije, mita i istorije u okviru teorijskih pozicija relevantnih, kako za kontekst u koji su postavljena dela Borislava Pekića i Džulijana Barnsa, tako i za razmatranje pripovedne aktivnosti u širem smislu. Jedna od centralnih hipoteza koje ovaj rad nastoji da razradi jeste pitanje priče kao mitosa, njenog telosa, kao i modusa narativne konfiguracije priče kao pripovedne aktivnosti koja predstavlja konstitutivni element, kako narativnog ideniteta, tako i onog čovekovog koji se kroz figure utopijsko-mitološko-istorijskog diskursa konstituiše kao biće jezika. Takođe se razmatra i ključno pitanje temporaliteta i konstituisanje priče kroz rekonfiguraciju dela u njegovom čitanju i doživljaju od strane recipijenta. U drugom poglavlju „Antropologija priče: Pekić-Barns“ primenjuje se analitičko-sintetički pristup u analizi navedenih dela. Dela Borislava Pekića postavljaju se u širi kontekst njegove ontološke filosofije kosmogonije i energijalizma. Pekićevo delo smo analizirali primenom obrnutog postupka demitomorfizacije i koristili se tzv. paralelnom literaturom koju je Pekić ispisivao kao onu koja prati izgradnju priče u njegovom romanesknom stvaralaštvu. Navedena dela Džulijana Barnsa takođe razmatramo u širem kontekstu konstituisanja narativnog identiteta priče za razliku od dosadašnjih studija koje su njegovo stvaralaštvo uglavnom razmatrale u kontekstu savremenih postmodernističkih teorija. Takođe, jedan od ciljeva ovog dela rada sastoji se u tome da se ukaže na idejno-tematsku vezu književnog stvaralaštva ova dva pisca, te i da se njihovo delo postavi u šire okvire pripovedne aktivnosti koja izlazi iz okvira nacionalne književnosti. Na osnovu sprovedene analize, dolazimo do zaključka da narativna konfiguracija njihovih priča predstavlja ironijsko-parodijsku, te i mitomorfnu masku koja tendencioznom mistifikacijom diskursa zapravo nastoji da dekonstruiše pojmovnu metafiziku utopije, mita i istorije. Analitičko-sintetičkim pristupom takođe smo nastojali da dokažemo u kojoj meri se njihova dela konstituišu kao pripovedno kretanje čija retorička ironija označava onu formu ironije u kojoj stav i ton govornika ili pisca ukazuju upravo na suprotno od onoga što priča zavodljivim diskursom iskazuje. Pekićeva i Barnsova priča odriče mogućnost izravne referencijalnosti tako što upućuje na referent koji ne može biti pripovedno profilisan. U tom smislu, njihovo stvaralaštvo nastoji da uputi i na tzv. nevidljivu (nedogađajnu, nearhiviranu) istoriju ljudskog duha. Iz navedenog proizilazi i jedna od osnovnih namera ovoga rada, a to je da se i metodološki gledano, Pekićevo i Barnsovo delo uspostavi kao izazov mišljenja koje se ne svodi isključivo na njihovu analizu u svojim literarnim svojstvima." ]
[ "" ]
application/pdf
sr
Универзитет у Крагујевцу, Филолошко-уметнички факултет
[ "info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/178018/RS//" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Крагујевцу
[ "utopija", "mit", "istorija", "Pekić", "Borislav", "1930-1992" ]
[ "Barnes", "Julian", "1946-" ]
[ "Utopijsko-mitološko-istorijski diskurs Borislava Pekića i Džulijana Barnsa", "Utopian, Mythological and Historical Discourse of Borislav Pekić and Julian Barnes" ]
[ "" ]
doctoralThesis
[ "BY-NC-ND" ]
Бошковић, Драган; Бубања, Никола; Настић, Радмила; Ђорић, Биљана; Теодоровић, Јасмина; Утопијско-митолошко-историјски дискурс Борислава Пекића и Джулијана Барнса; Утопијско-митолошко-историјски дискурс Борислава Пекића и Джулијана Барнса;
[ "http://nardus.mpn.gov.rs/bitstream/id/50752/jasmina_teodorovic_06072015.pdf", "https://nardus.mpn.gov.rs/bitstream/id/50752/jasmina_teodorovic_06072015.pdf", "http://nardus.mpn.gov.rs/bitstream/id/50751/Disertacija.pdf", "https://nardus.mpn.gov.rs/bitstream/id/50751/Disertacija.pdf", "https://fedorakg.kg.ac.rs/fedora/get/o:499/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_3843" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/3828
123456789-3828.pdf
yes
no
https://fedorakg.kg.ac.rs/fedora/get/o:364/bdef:Content/download
no
Funkcija adverbijalnih partikula u engleskim fraznim glagolima i njihovi srpski prevodni ekvivalenti
The function of adverbial particles in English phrasal verbs and their Serbian translation equivalents
[ "Novakov, Predrag" ]
[ "Kovačević, Miloš", "Mišić Ilić, Biljana M." ]
Glođović, Anica
2016-01-05T13:17:38
[ "2016-01-05T13:17:38", "2020-07-03T15:24:34" ]
2014-05-07
[ "https://nardus.mpn.gov.rs/handle/123456789/3828", "http://eteze.kg.ac.rs/application/showtheses?thesesId=999", "https://fedorakg.kg.ac.rs/fedora/get/o:364/bdef:Content/download" ]
[ "Ova disertacija bavi se proučavanjem funkcija adverbijalnih partikula down, off, up i out u engleskim fraznim glagolima i njihovim statusom u sistemima glagolskog vida odnosno glagolske semantike, a zatim i analizom njihovih srpskih prevodnih ekvivalenata. Na osnovu predmeta istraživanja ova disertacija može se svrstati u širu oblast kontrastivne lingvistike, a uže posmatrano u oblast deskriptivnog jednosmernog kontrastiranja engleskog i srpskog jezika. Ciljevi ovog istraživanja su višestruki i najpre se tiču se ispitivanja uticaja datih partikula, a zatim i morfosintaksičkih svojstava srpskih prevodnih ekvivalenata (prefiksacije) na kategorije glagolskog vida i tipa glagolske situacije sa namerom da se definiše njihova potencijalna vidska funkcija ili funkcija modifikovanja tipa glagolske situacije. Kao jezički uzorak za ispitivanje poslužila su dela savremene britanske književnosti i njihovi prevodi na srpski jezik te istraživanje odražava trenutno stanje na ovom polju. U radu su primenjene deskriptivne i kontrastivne metode za utvrđivanje morfosintaskičkih i semantičkih osobina fraznih glagola u engleskom jeziku i njihovih prevodnih ekvivalenata u srpskom jeziku. Isto tako, prikupljeni podaci analizirani su kvantitativno (primenom osnovne metode statističke obrade podataka) i kvalitativno (detaljnom analizom na osnovu sintaksičkih testova za utvrđivanje glagolskog vida i tipa glagolske situacije)." ]
[ "This dissertation focuses on the function of the adverbial particles down, off, up и out in English phrasal verbs and their status in the systems of verbal aspect and Aktionsart. It also encompasses the analysis of their Serbian translation equivalents in the same research frame. The subject of this study places it in the field of contrastive linguistics, i.e. descriptive one-way contrasting of English and Serbian. The aims of this thesis essentially include the analyses of the effects that these English particles and morphosyntactic features of the Serbian translation equivalents (prevailing prefixes) have on verbal aspect and Aktionsart; therefore, the goal of this study aims at defining English particles' and Serbian prefixes' potential aspectual function or Aktionsart modifying function in order to determine the similarities and differences between them. The empirical research was conducted on the corpus provided from the modern British novels and their translations into Serbian so that it can reflect the contemporary state in this field. This dissertation also applies descriptive and contrastive methods for yielding results on morphosyntactic and semantic features of English phrasal verbs and their Serbian translation equivalents. The collected data were subjected to both quantitative (basic statistical techniques) and qualitative analysis (a meticulous examination based on syntactic tests for determining the classes of verbal aspect and Aktionsart)." ]
application/pdf
sr
Универзитет у Крагујевцу, Филолошко-уметнички факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Крагујевцу
[ "kontrastivna lingvistika", "adverbijalna partikula", "frazni glagol u engleskom jeziku", "glagolski vid" ]
[ "" ]
[ "Funkcija adverbijalnih partikula u engleskim fraznim glagolima i njihovi srpski prevodni ekvivalenti", "The function of adverbial particles in English phrasal verbs and their Serbian translation equivalents" ]
[ "" ]
doctoralThesis
[ "BY-NC-ND" ]
Новаков, Предраг; Мишић Илић, Биљана М.; Ковачевић, Милош; Глођовић, Aница; Функција адвербијалних партикула у енглеским фразним глаголима и њихови српски преводни еквиваленти; Функција адвербијалних партикула у енглеским фразним глаголима и њихови српски преводни еквиваленти;
[ "https://nardus.mpn.gov.rs/bitstream/id/51057/Disertacija.pdf", "http://nardus.mpn.gov.rs/bitstream/id/51057/Disertacija.pdf", "https://fedorakg.kg.ac.rs/fedora/get/o:364/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_3828" ]
[ "" ]
[ "" ]
[ "" ]
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[ "" ]
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https://nardus.mpn.gov.rs/handle/123456789/10513
123456789-10513.pdf
yes
no
https://fedorakg.kg.ac.rs/fedora/get/o:1012/bdef:Content/download
no
Humani i posthumani identitet junaka u romanima Huana Gojtisola
[ "Sekulić, Mirjana" ]
[ "Stojanović, Jasna", "Karanović, Vladimir", "Bošković, Dragan" ]
Veljović, Jelica A.
2018-12-26T15:03:24
[ "2018-12-26T15:03:24", "2020-07-03T15:24:07" ]
2018-06-22
[ "https://nardus.mpn.gov.rs/handle/123456789/10513", "http://eteze.kg.ac.rs/application/showtheses?thesesId=6067", "https://fedorakg.kg.ac.rs/fedora/get/o:1012/bdef:Content/download" ]
[ "Doktorska disertacija Humani i posthumani identitet junaka u romanima Huana Gojtisola se bavi analizom predstava identiteta junaka u odabranim romanima savremenog španskog pisca Huana Gojtisola. U opseg analize ulazi pet Gojtisolovih romana, u kojima se kao protagonista pojavljuje isti književni junak: Znaci identiteta, Grof don Hulijan, Huan bez Zemlje, koji skupa čine „Trilogiju Alvara Mendiole”, Prizori nakon bitke i Prognan sa svih strana. Analiza ima za cilj da označi različite figuracije i predstave identiteta savremenog subjekta, koje je Gojtisolo formirao kroz svog junaka u periodu od 1966. godine, kada je objavljen prvi analizirani roman, do 2008. godine, kada je objavljen poslednji analizirani roman. Disertacija se sastoji iz devet poglavlja, od kojih su prvih pet poglavlja uvodnog i teorijsko-metodološkog karaktera, budući da se u njima predstavljaju početne hipoteze i opisuju osnovni metodološki pristup, teorijski i pojmovni okvir i osnovni koncepti iz različitih oblasti društveno-humanističkih nauka koji će biti korišćeni u analizi identiteta Gojtisolovog junaka. U naredna tri poglavlja se analitički predstavlja konstituisanje identiteta junaka u izabranim romanima, pojedinačno i komparativno, u skladu sa sličnostima u autorovom pristupanju identitetskoj izgradnji junaka. Poglavlja hronološki prate objavljivanje romana, budući da se teži dijahronijskom predstavljanju razvoja junakovog identiteta, kao i različitih poimanja identiteta od strane autora. Analiza romana se na početku fokusira na predstave o identitetu junaka Alvara Mendiole u romanima „Trilogije Alvara Mendiole”, koji će se tumačiti kroz ideje o konstiuisanju i dekonstrukciji identiteta, vodeći se konceptima drugosti, egzila, razlike, nomadizma, deteritorijalizacije i dekonstrukcije. Nakon toga se analizira identitet istog junaka, transfigurisanog u Monstruma iz Santjea u romanima Prizori nakon bitke i Prognan sa svih strana, fokusiranjem na postmodernistički pristup autora, a identitet će biti tumačen kroz paralele sa tekstom romana i autorovom kritikom zapadnoevropskih civilizacijskih vrednosti kao i kroz koncepte palimpsesta i diseminacije. U poslednjem poglavlju analize se tumačenje identiteta junaka vrši kroz posthumanističku teorijsku perspektivu, sa posebnim fokusom na roman Prognan sa svih strana. Ova poslednja figuracija i percepcija junaka će se pokazati kao potencijalna veza autora sa posthumanističkim teorijskim okvirom i idejama o subjektu u aktuelnom biotehnološki i digitalno unapređenom društvu. U zaključnom delu teze se pokazuje da je analiza identiteta u Gojtisolovim romanima jedno od ključnih polazišta za razumevanje autorove poetike i njegovog estetskog i etičkog usmerenja. Prateći analizu poslednjeg poglavlja, dolazi se do zaključka da se izabranim Gojtisolovim romanima može predstaviti čitava panorama predstava o identitetu, tj. identitetima savremenog subjekta, kao i razvoj njihovih različitih poimanja od druge polovine 20. veka do početka 21. veka." ]
[ "The dissertation Human and posthuman identity of the protagonist in the novels of Juan Goytisolo is focused on the interpretation and analysis of the representations of the protagonist’s identity in the selected novels of Spanish contemporary writer Juan Goytisolo. Five Goytisolo’s novels, with the same protagonist, have been included in the framework of the dissertation: Marks of identity, Count Julian, Juan the Landless, which that altogether form “Álvaro Mendiola Trilogy”, Landscapes after the battle and Exiled from almost everywhere. The analysis aims to illuminate different identity figurations and representations of the contemporary subject, who Goytisolo has been creating through his protagonist in the period from 1966, when the first analysed novel was published, to 2008, when the last analysed novel was published. The dissertation comprises nine chapters, out of which the first five are introductory, theoretical and methodological, due to the fact that they reflect and describe initial hypotheses, main methodological approach, theoretical and conceptual framework, as well as the basic notions from different fields in social sciences and humanities, which would be used in the analysis of Goytisolo’s protagonist identity. The next three chapters analytically present the constitution of the protagonist’s identity in the selected Goytisolo’s novels, both individually and comparatively, in accordance with the similarities in the author’s approach to the protagonist’s identity configuration. The chapters chronologically follow the publications of the novels, since it is an aim to diachronically depict the development of the protagonist’s identity, as well as the author’s different conceptualizations of the same. Therefore, the analysis is primarily focused on the notions and ideas about the identity of the protagonist Álvaro Mendiola in the novels of “Álvaro Mendiola Trilogy”. The character’s identity is explained through the ideas of constitution and deconstruction of identity, employing the concepts such as otherness, exile, difference, nomadism, deterritorialization and destruction. Afterwards, the identity representations of the same protagonist, transfigured into the Monster of le Sentier in the novels Landscapes after the battle and Exiled from almost everywhere are analyzed. The analysis of these identity figurations of the protagonist in the novels focuses on the author’s postmodernist approach, while identity is examined through parallels with the formal aspects of the novel and with the author’s critic of the Western European civilization values, as well as through the concepts of palimpsest and dissemination. In the last chapter of the analytical part of the dissertation, the protagonist’s identity is examined from posthumanist theoretical perspective, with the special emphasis on the novel Exiled from almost everywhere. This last figuration and perception of the protagonist will indicate the potential relations between the author’s literary poetics and the posthumanist theoretical framework and ideas about the subject in the contemporary biotechnologically and digitally improved humanity. In the concluding chapter of the dissertation, it is shown that the analysis of identity in Goytisolo’s novels may be seen as one of the key points for understanding the author’s poetics, and his aesthetical and ethical bias. Comprehending the analysis of the last chapter, it can be concluded that it is possible to discern the whole panorama of the contemporary identity representations within the selected frame of Goytisolo’s novels, as well as the development of their different understandings from the second half of the 20th century until the beginning of the 21st century." ]
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Универзитет у Крагујевцу, Филолошко-уметнички факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Крагујевцу
[ "posleratni španski roman", "savremeni španski roman", "identitet", "postmodernizam", "posthumanizam" ]
[ "Spanish Civil War novel", "Spanish contemporary novel", "identity", "postmodernism", "posthumanism" ]
[ "Humani i posthumani identitet junaka u romanima Huana Gojtisola" ]
[ "" ]
doctoralThesis
[ "BY-NC-ND" ]
[ "https://nardus.mpn.gov.rs/bitstream/id/50952/Disertacija.pdf", "https://nardus.mpn.gov.rs/bitstream/id/50953/Jelica_Veljovic_FILUM.pdf", "http://nardus.mpn.gov.rs/bitstream/id/50952/Disertacija.pdf", "http://nardus.mpn.gov.rs/bitstream/id/50953/Jelica_Veljovic_FILUM.pdf", "https://fedorakg.kg.ac.rs/fedora/get/o:1012/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_10513" ]
[ "" ]
[ "" ]
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[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/11816
123456789-11816.pdf
yes
no
https://fedorakg.kg.ac.rs/fedora/get/o:1179/bdef:Content/download
no
Cirkulišuće mikropartikule i biomarkeri oksidacionog stresa kod pacijenata obolelih od reumatoidnog artritisa
Circulating microparticles and biomarkers of oxidative stress in patients with rheumatoid arthritis
[ "Antović, Aleksandra" ]
[ "Veselinović, Mirjana", "Jakovljević, Vladimir", "Anđelković, Nebojša", "Petronijević, Milan" ]
Vranić, Aleksandra
2020-01-27T14:06:14
[ "2020-01-27T14:06:14", "2020-07-03T15:20:33" ]
2019-11-28
[ "https://nardus.mpn.gov.rs/handle/123456789/11816", "http://eteze.kg.ac.rs/application/showtheses?thesesId=7058", "https://fedorakg.kg.ac.rs/fedora/get/o:1179/bdef:Content/download" ]
[ "Uvod: Reumatoidni artritis (RA) je hronična, inflamatorna, autoimuna bolest koja uzrokuje sinovitis i destruktivni artritis, progresivno oštećenje hrskavice i zglobova, deformitete praćene van-zglobnim, sistemskim manifestacijama bolesti, snažan sistemski inflamatorni odgovor sa ubrzanim razvojem ateroskleroze, kao i invaliditet, skraćeni životni vek i povećan mortalitet. Cilj: Ispitati uticaj RA na koncentraciju mikropartikula, aktiviranje hemostaze, pojavu prokoagulabilnog stanja, fibrinsku mrežu i morfologiju vlakana fibrinskog ugruška, parametre oksidacionog stresa i antioksidacionog sistema zaštite, kao i uticaj reumatoidnog artritisa na biohemijske, hematološke i hemostatske parametre i sve analize uporediti sa zdravim ispitanicima. Materijal i metode: Kod 42 pacijenta sa RA i 48 zdravih kontrola, ispitivana je koncentracija mikropartikula protočnom citometrijom pri čemu su praćene mikropartikule koje potiču od trombocita, leukocita, monocita, endotelne mikropartikule, mikropartikule koje eksprimiraju P-selektin i E-selektin i tkivni faktor. Hemostaza i pojava prokoagulabilnog stanja praćena je globalnim metodama, endogenim trombin potencijalom i ukupnim hemostatski potencijalom. Elektronskom mikroskopijom ispitan je uticaj RA na fibrinsku mrežu i morfologiju vlakana fibrinskog ugruška. Redoks status je određivan spektrofotometrijski. Kompletne biohemijske, hematološke i hemostatske analize su urađene u Centralnoj laboratoriji Kliničkog centra Kragujevac. Rezultati: Ukupna koncentracija mikropartikula kao i koncentracija mikropartikula koje potiču od trombocita, monocita, leukocita i P-selektina bile su povišene kod pacijenata sa RA u odnosu na zdrave ispitanike. Globalne metode hemostaze ukazuju da je koagulacija snažno pogođena dugotrajnom inflamacijom kod pacijenata sa RA, i menopauzom kod zdravih žena. Elektronskom mikroskopijom pokazano je da pacijenti sa reumatoidnim artritisom kao i zdrave kontrole u menopauzi imaju gušću strukturu fibrinskog ugruška sa manjim porama, koji je manje osetljiv na fibrinolizu. Prooksidacioni i antioksidacioni parametri praćeni u studiji ukazuju na postojanje oksidacionog stresa i smanjenje aktivnosti antioksidacionog sistema zaštite kod pacijenata sa RA. I RA i menopauza dovode do značajnog smanjenja mineralne gustine kostiju. Svi nespecifični parametri inflamacije bili su povišeni kod pacijenata sa RA. Zaključak: Mikropartikule koje potiču od trombocita mogu biti potencijalni biomarker za trombocitnu reaktivnost u RA koja predstavlja prediktor za nastanak tromboze i povećanje kardiovaskularnog rizika. Parametri globalnih hemostatskih metoda mogu biti korisni u dijagnostikovanju i praćenju hiperkoagulacionog stanja kod pacijenata sa RA. Kod pacijenata sa reumatoidnim artritisom postoji potreba za suplementacijom antioksidansima." ]
[ "Introduction: Rheumatoid Arthritis (RA) is a chronic, inflammatory, autoimmune disease that causes synovitis and destructive arthritis, progressive cartilage and joints damage, deformities followed by outside of the articular manifestations, systemic disease manifestations, a strong systemic inflammatory response with rapid development of atherosclerosis, disabilities, shortened life expectancy and increased mortality. Aim: We aimed this study, therefore, to explore the effect of RA on the microparticles expression in peripheral blood, to assess hemostatic disturbances and the occurrence of procoagulable state, to identify fibrin clot properties and the morphology of fibrin clot fibers, to determine parameters of oxidative stress and the antioxidantative system as well as the impact of rheumatoid arthritis on biochemical, hematological and hemostatic parameters and to compare all the analyzes with healthy subjects. Material and methods: In 42 patients with RA and 48 healthy controls, the following parameters were examined using appropriate methods. The concentration of microparticles was determined by flow cytometry, whereby microparticles derived from platelets, leukocytes, monocytes, endothelial microparticles, microparticles expressing P-selectin, Eselectin and a tissue factor were determined. Parameters of hemostasis and the occurrence of a procoagulable condition were followed by global hemostatic methods, endogenous thrombin potential and overall hemostasis potential. Тhe effect of RA on the fibrin network and the morphology of fibrin clot fibers was analyzed by electron microscopy. Redox status was determined spectrophotometrically. Biochemical, haematological and hemostatic analyzes were done in the Central Laboratory of the Clinical Center Kragujevac. Results: The total concentration of microparticles, the concentration of platelet-, мonocyte-, leukocyte- and P-selectin-derived microparticles, were elevated in patients with RA compared to healthy subjects. Global hemostatic methods indicate that coagulation is strongly affected by long-term inflammation in patients with RA, and menopause in healthy women. Electron microscopy shown that patients with RA as well as healthy control had denser fibrin structures with smaller pores which are less prone to fibrinolysis. The prooxidative and antioxidantive parameters followed in the study indicate the existence of oxidative stress and decreased activity of the antioxidative system in patients with RA. Both RA and menopause lead to a significant decrease in bone mineral density. All non-specific inflammatory parameters were elevated in patients with RA. Conclusions: Platelet-derived microparticles could be a potential biomarker for platelet reactivity in RA, which is a predictor of thrombosis and increased cardiovascular risk. Global hemostatic methods can be useful in hypercoagulation diagnosing and monitoring in patients with RA. Futhermore, in patients with rheumatoid arthritis there is a need for supplements containing antioxidants." ]
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Универзитет у Крагујевцу, Факултет медицинских наука
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Крагујевцу
[ "reumatoidni artritis", "mikropartikule", "globalne metode hemostaze", "elektronska mikroskopija", "oksidacioni stres" ]
[ "rheumatoid arthritis", "microparticles", "global hemostatic methods", "electron microscopy", "oxidative stress" ]
[ "Cirkulišuće mikropartikule i biomarkeri oksidacionog stresa kod pacijenata obolelih od reumatoidnog artritisa" ]
[ "Circulating microparticles and biomarkers of oxidative stress in patients with rheumatoid arthritis" ]
doctoralThesis
[ "BY-NC-ND" ]
[ "https://nardus.mpn.gov.rs/bitstream/id/50253/Disertacija.pdf", "https://nardus.mpn.gov.rs/bitstream/id/50254/Aleksandra_Vranic_Medicina.pdf", "http://nardus.mpn.gov.rs/bitstream/id/50253/Disertacija.pdf", "http://nardus.mpn.gov.rs/bitstream/id/50254/Aleksandra_Vranic_Medicina.pdf", "https://fedorakg.kg.ac.rs/fedora/get/o:1179/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_11816" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
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[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/9439
123456789-9439.pdf
yes
no
https://fedorakg.kg.ac.rs/fedora/get/o:963/bdef:Content/download
no
Značaj koncentracija kolagena tip iv, transferina i vezujućeg proteina masnih kiselina jetre u urinu za rano otkrivanje dijabetesne nefropatije
Significance of collagen type IV, transferrin and liver fatty acid binding protein in urine for early detection of diabetic nephropathy
[ "Mijušković, Mirjana" ]
[ "Petrović, Dejan", "Živančević-Simonović, Snežana", "Đukić, Aleksandar", "Vojvodić, Danilo" ]
Terzić, Brankica
2018-05-19T12:38:35
[ "2018-05-19T12:38:35", "2020-07-03T15:20:00" ]
2018-02-23
[ "https://nardus.mpn.gov.rs/handle/123456789/9439", "http://eteze.kg.ac.rs/application/showtheses?thesesId=5750", "https://fedorakg.kg.ac.rs/fedora/get/o:963/bdef:Content/download" ]
[ "" ]
[ "Diabetic nephropathy is one of the leading cause of chronic kidney disease and end-stage renal disease. It occurs in 20-40% patients with diabetes mellitus, and microalbuminuria is still considered as the first sign of diabetic nephropathy. Low sensitivity and specificity of microalbuminuria leads to more sensitive biomarkers that may be used to detect diabetic nephropathy at an earlier stage with higher accuracy. This study was carried out to determine whether urinary biomarkers such as collagen type IV, transferrin and L-FABP can serve as an indicator of diabetic nephropathy. The study included 80 diabetic adult patients who were classified into two groups: group 1 - normoalbuminuric patients (albumin excretion up to 30 mg/d), group 2 – microalbuminuric patients (albumin excretion from 30-300 mg/d) and 10 healthy controls. In our group, 44 (55%) patients were male and 36 (45%) female, mean age 59.85± 8.87 years. Prevalence of microalbuminuria was 41.25% (33 patients) and 58.75% were normoalbuminuric (47 patients). During the trial, urinary biomarker concentrations were found to be significantly higher in patients with microalbuminuria compared with patients who were normoalbuminuric. There was no statistically significant difference in the level of urinary biomarkers compared to glycoregulation, body weight index, and duration of diabetes. The results of this study have shown that collagen type IV, transferrin and L-FABP in 24 hours and the first morning urine are sensitive and specific tests for early diagnosis of diabetic nephropathy. Among them, the greatest sensitivity and specificity was shown by urinary transferrin. Although there was a correlation between urinary transferrin concentration and diabetic retinopathy." ]
application/pdf
sr
Универзитет у Крагујевцу, Факултет медицинских наука
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Крагујевцу
[ "dijabetes melitus", "mikroalbuminurija", "biomarker", "kolagen tip IV", "transferin", "L-FABP" ]
[ "Diabetes mellitus", "microalbuminuria", "biomarker", "collagen type IV", "transferrin. L-FABP" ]
[ "Značaj koncentracija kolagena tip iv, transferina i vezujućeg proteina masnih kiselina jetre u urinu za rano otkrivanje dijabetesne nefropatije" ]
[ "Significance of collagen type IV, transferrin and liver fatty acid binding protein in urine for early detection of diabetic nephropathy" ]
doctoralThesis
[ "BY-NC-ND" ]
Мијушковић, Мирјана; Војводић, Данило; Ђукић, Aлександар; Живанчевић-Симоновић, Снежана; Петровић, Дејан; Терзић, Бранкица; Значај концентрација колагена тип ив, трансферина и везујућег протеина масних киселина јетре у урину за рано откривање дијабетесне нефропатије; Значај концентрација колагена тип ив, трансферина и везујућег протеина масних киселина јетре у урину за рано откривање дијабетесне нефропатије;
[ "https://nardus.mpn.gov.rs/bitstream/id/50073/Disertacija.pdf", "https://nardus.mpn.gov.rs/bitstream/id/50074/Izvestaj_Brankica_Terzic_Medicina.pdf", "http://nardus.mpn.gov.rs/bitstream/id/50073/Disertacija.pdf", "http://nardus.mpn.gov.rs/bitstream/id/50074/Izvestaj_Brankica_Terzic_Medicina.pdf", "https://fedorakg.kg.ac.rs/fedora/get/o:963/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_9439" ]
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https://nardus.mpn.gov.rs/handle/123456789/3811
123456789-3811.pdf
yes
no
https://fedorakg.kg.ac.rs/fedora/get/o:359/bdef:Content/download
no
Redukcija dimenzionalnosti podataka u klasifikacionim problemima veštačke inteligencije
[ "Veljović, Alempije" ]
[ "Micić, Živadin", "Milanović, Dragan", "Radenković, Božidar", "Milošević, Danijela" ]
Novaković, Jasmina Đ.
2016-01-05T13:16:21
[ "2016-01-05T13:16:21", "2020-07-03T15:22:01" ]
2013
[ "https://nardus.mpn.gov.rs/handle/123456789/3811", "http://eteze.kg.ac.rs/application/showtheses?thesesId=969", "https://fedorakg.kg.ac.rs/fedora/get/o:359/bdef:Content/download" ]
[ "Središnji problem mašinskog učenja je identifikovanje reprezentativnog seta podataka na osnovu koga će se konstruisati klasifikacioni model za svaki pojedinačni zadatak. U ovoj doktorskoj disertaciji istražujemo problem redukcije dimenzionalnosti podataka u klasifikacionim problemima veštačke inteligencije korišćenjem različitih metoda za selekciju i ekstrakciju atributa. Metode selekcije atributa obuhvataju: metode filtriranja, metode prethodnog učenja i ugrađene metode. Osnovna hipoteza je da je moguće znatno poboljšati performanse sistema za induktivno učenje pravila u problemima klasifikacije, primenom različitih metoda i tehnika redukcije dimenzionalnosti podataka. Evaluacija svakog atributa u setu podataka vrši se na osnovu predloženog generičkog modela za selekciju i vrednovanje svakog pojedinačnog atributa. U radu, biće predložen veliki broj algoritama koji se koriste u redukciji dimenzionalnosti podataka i biće izvršena njihova evaluacija na veštačkim i prirodnim skupovima podataka. Za potrebe klasifikacije koristi se veliki broj algoritama: k-najbliži susedi, Bajesovi klasifikatori, stabla odlučivanja, veštačke neuronske mreže i potporni vektori. Eksperimentalni rezultati pokazuju da se ovim metodama mogu brzo identifikovati nevažni, redundantni atributi, kao i šum u podacima ako on postoji; kao i oni atributi koji su značajni za izučavanu pojavu. U radu se istražuje uticaj redukcije dimenzionalnosti podataka na izgradnju modela, što je naročito značajno kada imamo veliki broj atributa i veliki broj instanci, što je čest slučaj posebno u bioinformatici, analizi dokumenata, slika i glasa. U radu, biće razmatran uticaj metoda za selekciju i ekstrakciju atributa na rad svakog pojedinačnog algoritma za klasifikaciju, bez obzira da li on već ima ugrađene metode za predselekciju atributa. Ako algoritam već ima ugrađenu predselekciju atributa, biće istražena dobit od nezavisne predselekcije atributa." ]
[ "The central problem of machine learning is to identify a representative set of data to construct a classification model for each individual task. In this doctoral dissertation, we investigate the problem of dimensionality reduction of data in the classification problems of artificial intelligence using different methods for selecting and extracting attributes. Methods of selection attributes include: filter, wrappers and embedded methods. The basic hypothesis is that it is possible to significantly improve the performance of the system for inductive learning of rules for classification problems, using different methods and techniques for data dimensionality reduction. The evaluation of each attribute in the data set is based on the proposed generic model for the selection and evaluation of each attribute. This paper will be proposed a number of algorithms that are used in reducing the dimensionality of the data and their evaluation will be performed on artificial and natural data sets. For the purposes of classification is used a large number of algorithms: k-nearest neighbors, Bayesian classifiers, decision trees, artificial neural networks and support vector machine. The experimental results show that these methods can quickly identify irrelevant or redundant attributes, as well as noise in the data, if it exists; also those attributes that are important for the studied problem. This paper will examines the impact of dimensionality reduction of data to build the model, which is especially important when we have a large number of attributes and a large number of instances, which is often the case, especially in bioinformatics, analysis of documents, images and voice. In this paper, the impact of methods for selection and extraction of the attributes will be considered for each algorithm for classification, regardless of whether they already have a built-in method for preselection of attributes. If the algorithm already has a built-in method for preselection of attributes, will be investigated the influence of an independent selection of attributes." ]
application/pdf
sr
Универзитет у Крагујевцу, Факултет техничких наука, Чачак
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc/4.0/" ]
Универзитет у Крагујевцу
[ "Veštačka inteligencija", "ekstrakcija atributa", "klasifikacija", "metode filtriranja", "metode prethodnog učenja" ]
[ "004.8" ]
[ "Redukcija dimenzionalnosti podataka u klasifikacionim problemima veštačke inteligencije" ]
[ "" ]
doctoralThesis
[ "BY-NC" ]
Вељовић, Aлемпије; Милошевић, Данијела; Раденковић, Божидар; Милановић, Драган; Мицић, Живадин; Новаковић, Јасмина Ђ.; Редукција димензионалности података у класификационим проблемима вештачке интелигенције; Редукција димензионалности података у класификационим проблемима вештачке интелигенције;
[ "https://nardus.mpn.gov.rs/bitstream/id/50586/Disertacija.pdf", "http://nardus.mpn.gov.rs/bitstream/id/50586/Disertacija.pdf", "https://fedorakg.kg.ac.rs/fedora/get/o:359/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_3811" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
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https://nardus.mpn.gov.rs/handle/123456789/3835
123456789-3835.pdf
yes
no
https://fedorakg.kg.ac.rs/fedora/get/o:456/bdef:Content/download
no
Leksičko-semantička analiza somatizama u frazeologiji savremenog španskog i srpskog jezika: kontrastivni pristup
Análisis léxico-semántico de los fraseologismos somáticos en español y serbio contemporáneo: estudio contrastivo
[ "Pejović, Anđelka" ]
[ "Jovanović, Ana", "Filipović, Jelena", "Ramić, Nikola", "Mršević-Radović, Dragana" ]
Trivić, Aneta
2016-01-05T13:17:40
[ "2016-01-05T13:17:40", "2020-07-03T15:23:04" ]
2015-04-30
[ "https://nardus.mpn.gov.rs/handle/123456789/3835", "http://eteze.kg.ac.rs/application/showtheses?thesesId=1788", "https://fedorakg.kg.ac.rs/fedora/get/o:456/bdef:Content/download" ]
[ "Ovaj rad pripada polju kontrastivnih frazeoloških proučavanja i za svoj opšti cilj ima poređenje frazeoloških sistema španskog i srpskog jezika. Konkretnije vrši se leksička i semantička i, uže, konceptualna analiza somatskih frazeologizama s komponentama glava/cabeza, oko/ojo, ruka/brazo i šaka/mano. Cilj je da se na temelju prikupljene građe sprovede njihova semantička sistematizacija, analiziraju sličnosti i razlike, i ukaže na vrstu međujezičkog odnosa i stepen prevodne ekvivalencije. Korpus na kojem se vrši paraleleni opis sačinjen je od nešto više od 870 somatskih frazeologizama, ekscerpiranih iz opštih i frazeoloških jednojezičnih rečnika. Deskripcija frazeologizama obuhvata i pragmatičke vrednosti, te je njihova upotreba ilustrovana kroz kontekstualizovane primere koji su preuzeti iz odgovarajućih korpusa. U cilju utvrđivanja frazeoloških specifičnosti, podudarnosti i nepodudarnosti, odnosno odgovora na pitanje kako govornici srpskog i španskog jezika u svojoj slici sveta konceptualizuju sadržaje koje njima iskazuju, uspostavljaju se konceptualni tematski blokovi. Budući da je tema interdisciplinarnog karaktera, polazi se od teorijsko-metodološkog okvira na kojem se zasniva istraživanje i iznose se najznačajnije teorijske postavke leksikologije i semantike, kontrastivne analize i kognitivne lingvistike, s posebnim osvrtom na frazeologiju i kontrastivnu frazeologiju. Predstavljaju se frazeološke jedinice, njihove osnovne karakteristike i mogućnosti klasifikacije u okvirima španske i srpske lingvistike. U istraživanju su primenjene metode kontrastivne i konceptualne analize, a prevodna ekvivalencija od suštinskog je značaja za rešavanje problema uporedivosti. Rezultati kontrastivne analize nedvosmisleno ukazuju da lekseme glava/cabeza, oko/ojo, ruka/brazo, šaka/mano zauzimaju važno mesto u leksičkim sistemima srpskog i španskog jezika, da imaju razvijenu simboliku i polisemiju, kao i učestalu upotrebu i frazemotvornu produktivnost. Stoga su validan pokazatelj međujezičkih odnosa njihovih frazeoloških sistema. Upoređivani somatski frazeologizmi pokazuju da metafore nastale na bazi ljudskog tela i iskustva generišu širok spektar razuđenih značenja koja su struktuirana u semantičke skupove. Kod sva tri somatizma utvrđena su tri konceptualno-značenjska bloka (radnje koje čovek vrši, apstraktne pojave koje ga okružuju i karakteristike koje mu se pripisuju), koja se dalje razrađuju prema istom kriterijumu. Potvrđena je univerzalno prisutna antropocentričnost i antropometričnost u somatskoj frazeologiji, kao i bazična semantička, formalna i funkcionalna međujezička korespondencija između frazeoloških sistema ova dva jezika. U manjoj meri uočene su sporadične nepodudarnosti u konceptualizacijama, koje prouzrokuju odsustvo svake značenjske ekvivalencije. Takvi nekomparabilni delovi uslovljeni su kulturološkim specifičnostima i nose idiosinkratičnu informaciju, karakterističnu za određenu govornu zajednicu." ]
[ "" ]
application/pdf
sr
Универзитет у Крагујевцу, Филолошко-уметнички факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Крагујевцу
[ "frazeologija", "leksikologija", "semantika", "kontrastivna lingvistika", "prevodna ekvivalencija", "kognitivna lingvistika", "konceptualna analiza", "somatizam", "španski jezik", "srpski jezik." ]
[ "fraseología", "lexicología", "semántica", "lingüística contrastiva", "equivalencia traductológica", "lingüística cognitiva", "análisis conceptual", "somatismo", "lengua española", "lengua serbia." ]
[ "Leksičko-semantička analiza somatizama u frazeologiji savremenog španskog i srpskog jezika: kontrastivni pristup", "Análisis léxico-semántico de los fraseologismos somáticos en español y serbio contemporáneo: estudio contrastivo" ]
[ "" ]
doctoralThesis
[ "BY-NC-ND" ]
Пејовић, Aнђелка; Јовановић, Aна; Мршевић-Радовић, Драгана; Филиповић, Јелена; Рамић, Никола; Тривић, Aнета; Лексичко-семантичка анализа соматизама у фразеологији савременог шпанског и српског језика: контрастивни приступ; Лексичко-семантичка анализа соматизама у фразеологији савременог шпанског и српског језика: контрастивни приступ;
[ "http://nardus.mpn.gov.rs/bitstream/id/50691/Disertacija.pdf", "https://nardus.mpn.gov.rs/bitstream/id/50691/Disertacija.pdf", "https://nardus.mpn.gov.rs/bitstream/id/50692/aneta_trivic_24.02.2015.pdf", "http://nardus.mpn.gov.rs/bitstream/id/50692/aneta_trivic_24.02.2015.pdf", "https://fedorakg.kg.ac.rs/fedora/get/o:456/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_3835" ]
[ "" ]
[ "" ]
[ "Este trabajo pertenece al campo de los estudios fraseológicos contrastivos y como objetivo general tiene la comparación de los sistemas fraseológicos español y serbio. Más concretamente, se realiza el análisis léxico y semántico, y más específicamente uno conceptual, de los fraselogismos somáticos que contienen componentes глава /cabeza, око/ojo, рука/brazoyшака/mano. A base del material recogido intentamos realizar su sistematización semántica, analizar las similitudes y diferencias, e indicar el tipo de la relación interlingüística y el grado de la equivalencia traductológica. El corpus utilizado en el estudio paralelo se basa en un poco más de 870 fraseologismos somáticos, y procede de los diccionarios monolingües generales y fraseológicos. La descripción de los fraseologismos incluye la información pragmática y su uso está ilustrado con los ejemplos textualizados obtenidos de los corpus correspondientes. Con el fin de determinar las especificidades fraseológicas, las coincidencias y discrepancias, y responder de cómo los hablantes del serbio y español en su representación del mundo conceptualizan los contenidos expresados mediante estos fraseologismos, se establecen los bloques temáticos. Dado el carácter sumamente interdisciplinar del tema, se establece el marco teórico y metodológico en el cual se basa la investigación, y se sintetizan los fundamentos teóricos de lexicología y semántica, análisis contrastivo y lingüística cognitiva, con énfasis especial en fraseología y fraseología contrastiva. Se representan las unidades fraseológicas, sus características esenciales y posibilidades para su clasificación dentro de las lingüísticas española y serbia. Los métodos aplicados en la investigación son el análisis contrastivo y conceptual, y la equivalencia traductológica ha sido esencial en la resolución de los problemas de comparabilidad. Los resultados del análisis contrastivo indiscutiblemente demuestran que los lexemas глава /cabeza, око/ojo, рука/brazo y шака/mano ocupan un lugar importante dentro de los sistemas léxicos de las lenguas española y serbia, que tienen la simbología y polisemia muy desarrolladas, igual que la frecuencia de uso y la productividad fraseológica. Debido a eso, sirven como el indicador válido de las relaciones interlingüísticas de sus sistemas fraseológicos. Los fraseologismos somáticos comparados muestran que las metáforas basadas en el cuerpo y la experiencia humana generan una amplia gama de significados diferentes, estructurados en los conjuntos semánticos. En el caso de los tres somatismos se establecen tres bloques semántico-conceptuales (acciones realizadas por el hombre, fenómenos abstractos y las descripciones del hombre y su contorno), que se clasifican luego según el mismo criterio. Se confirman el carácter universal antropocéntrico y antropométrico de la fraseología somática, igual que la correspondencia básica, semántica, formal y funcional, de los sistemas fraseológicos de estas dos lenguas. Se observan casos esporádicos de las discrepancias conceptuales que producen la ausencia de la equivalencia traductológica. Tales fenómenos incomparables son ocasionados por las peculiaridades culturales y llevan una información idiosincrásica, típica para una comunidad de habla." ]
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https://nardus.mpn.gov.rs/handle/123456789/6857
123456789-6857.pdf
yes
no
https://fedorakg.kg.ac.rs/fedora/get/o:697/bdef:Content/download
no
Razvoj i eksploatacija bezbednosnog modula i njegov uticaj na kvalitet e-obrazovanja
Development and implementation of security module and its influence on quality of e-education
[ "Milošević, Danijela" ]
[ "Krneta, Radojka", "Simić, Dejan", "Urošević, Vlade" ]
Milošević, Marjan
2016-10-22T10:06:25
[ "2016-10-22T10:06:25", "2020-07-03T15:21:52" ]
2016-09-22
[ "https://nardus.mpn.gov.rs/handle/123456789/6857", "http://eteze.kg.ac.rs/application/showtheses?thesesId=4066", "https://fedorakg.kg.ac.rs/fedora/get/o:697/bdef:Content/download" ]
[ "Elektronsko obrazovanje postalo je sastavni deo modernog društva znanja. S obzirom na to da se najvećim delom oslanja na informacione tehnologije, postavlja se pitanje kakav uticaj ima bezbednost informacija na kvalitet e- obrazovanja i kako se može unaprediti bezbednost korisnika u okruženjima za e- učenje. U doktoratu je prikazan razvoj bezbednosnog modula. Ovaj modul kreiran je sa zadatkom da deluje kao integrisani deo okruženja za e-učenje: da prati korisnikove aktivnosti, primenjuje mere zaštite i diseminira elemente bezbednosne politike. Dati su opis implementacije, kao i toka i rezultata istraživanja uticaja modula na konstrukte koji su povezani sa kvalitetom e- obrazovanja: poverenje u sistem za e-učenje i prihvaćenost tehnologija. Sam proces razvoja zasnovan je na standardima iz oblasti bezbednosti informacija (ISO) i e-obrazovanja (IEEE, IMS), a kao ulazni parametri uzeti su i kriterijumi za obezbeđenje kvaliteta. Celokupan razvoj, kao i implementacija i evaluacija modula sprovedeni su kroz PDCA ciklus. Tokom projektovanja modula razvijen je i holistički model bezbednosti u e-učenju, nadgrađena je standardna arhitektura za e-učenje i adaptiran model učenika. Fokus modula je na korisniku, pa je stoga IMS model učenika (IMS LIP) dopunjen strukturom koja ima za zadatakda evidentira bezbednosne parametre učenikovog ponašanja. Ovaj dopunjeni model sastavni je deo nadgrađene LTSA arhitekture, nazvane seLTSA, koja za zadatak ima da pruži okvire za unapređenje bezbednosti procesa e-obrazovanja. Ključni deo nadgradnje je upravo modul, eLearnion, koji orkestrira bezbednošću. U svrhu evaluacije modula i provere hipoteza, modifikovani su postojeći modeli poverenja i prihvatanja tehnologija. Modul je realizovan kao dodatak Moodle-a, okruženja za učenje otvorenog koda, primenom metode brzog razvoja prototipa (rapid prototyping). Zbog zahteva pojedinih funkcija za dubljom integracijom u samo okruženje, bilo je neophodno izvršiti i određene izmene jezgra Moodle-a. Modul je implementiran i testiran u sklopu e-kursa na koji su upisani učenici (studenti). Kurs je trajao tri meseca, nakon čega su učenici anketirani. Pokazano je da je primenom standarda iz oblasti bezbednosti informacija moguće kreirati modul koji svojim aktivnostima doprinosi ispunjenju kriterijuma za obezbeđenje kvaliteta. Potvrđeno je da je bezbednost jedan od najuticajnijih faktora poverenja korisnika u sistem za e-učenje. Delimično je potvrđeno da su bezbednosni elementi, formulisani kroz bezbednosni modul, značajni za prihvatanje tehnologija." ]
[ "Electronic education has become an integral part of modern knowledge society. Having in mind that it mostly depends on information technology, a question is yielded on how the information security influences e-education quality and in what way the user security may be improved in learning environments. The development of security module is shown in thesis. Module is created in order to act as integral part of the e-learning environment: to monitor user's activities, apply security measures and disseminate elements of information security policy. Description of implementation is given as well as flow and results of research of module's influence on construct coupled with quality such as trust in learning environment and technology acceptance. The development process is based on standards in area of information security (ISO) and learning technologies (IEEE, IMS) and the e-learning quality criteria are taken as input. During the module design, a holistic model of security in e-learning was developed. Additionally, the standard e-learning architecture was upgraded and the standard learner model was adapted. Module is focused on user, therefore the IMS learner model (IMS LIP) is supplemented with structure with task of keeping security parameters of learner's behavior. This supplemented model is building block of upgraded LTSA architecture, called seLTSA, with goal of providing framework for security improvement of e-education processes. Key part of this upgrade is the very module, called eLearnion, which orchestrate with security. In favor of module evaluation and hypothesis check, the existing trust and technology acceptance models are modified. Module is made as plugin for Moodle, open source learning environment, using the rapid prototype method. Because some function required deeper integration in the very environment, certain modification of Moodle code was needed. Modul is implemented and tested inside an e-course with students enrolled. Course lasted three months and learners were surveyed afterward. It is shown that it is possible to create module whose activities contribute to fulfillment of quality assurance criteria by using information security standard. It is confirmed that security is very important factor of user trust in e-learning system. It is partly confirmed that security elements, formulated through security module, are significant for technology acceptance." ]
application/pdf
sr
Универзитет у Крагујевцу, Факултет техничких наука, Чачак
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc/4.0/" ]
Универзитет у Крагујевцу
[ "e-obrazovanje", "bezbednost informacija", "LTSA", "Moodle", "bezbednosni modul" ]
[ "e-learning", "e-education", "information security", "LTSA", "Moodle", "security module" ]
[ "Razvoj i eksploatacija bezbednosnog modula i njegov uticaj na kvalitet e-obrazovanja", "Development and implementation of security module and its influence on quality of e-education" ]
[ "" ]
doctoralThesis
[ "BY-NC" ]
Милошевић, Данијела; Крнета, Радојка; Урошевић, Владе; Симић, Дејан; Милошевић, Марјан; Развој и експлоатација безбедносног модула и његов утицај на квалитет е-образовања; Развој и експлоатација безбедносног модула и његов утицај на квалитет е-образовања;
[ "https://nardus.mpn.gov.rs/bitstream/id/50532/Disertacija5078.pdf", "https://nardus.mpn.gov.rs/bitstream/id/50533/Izvestaj_Marjan_Milosevic_FTN.pdf", "http://nardus.mpn.gov.rs/bitstream/id/50532/Disertacija5078.pdf", "http://nardus.mpn.gov.rs/bitstream/id/50533/Izvestaj_Marjan_Milosevic_FTN.pdf", "https://fedorakg.kg.ac.rs/fedora/get/o:697/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_6857" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
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[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/9388
123456789-9388.pdf
yes
no
https://fedorakg.kg.ac.rs/fedora/get/o:955/bdef:Content/download
no
Unapređenje učenja jezika struke putem hibridne nastave i sistema za upravljanje učenjem
The improvement of esp learning through blended learning and learning management systems
[ "Blagojević, Savka" ]
[ "Đorđević, Jasmina", "Mišković-Luković, Mirjana", "Marković, Dejan" ]
Stojković-Trajković, Miljana
2018-04-23T10:45:39
[ "2018-04-23T10:45:39", "2020-07-03T15:23:54" ]
2018-03-17
[ "https://nardus.mpn.gov.rs/handle/123456789/9388", "http://eteze.kg.ac.rs/application/showtheses?thesesId=5716", "https://fedorakg.kg.ac.rs/fedora/get/o:955/bdef:Content/download" ]
[ "Disertacija Unapređenje učenja jezika struke putem hibridne nastave i sistema za upravljanje učenjem bavi se analizom unapređenja učenja jezika struke primenom hibridne nastave i sistema za upravljanje učenjem na primeru primene platforme Edmodo. Tematski okvir ove disertacije kao i sprovedeno istraživanje može se svrstati u aktuelne teme metodike učenja stranog jezika i net lingvistike. Disertacija je imala za cilj da utvrdi koliko se ovladavanje specifičnim vokabularom poslovnog jezika može poboljšati primenom sistema za upravljanje učenjem (Learning Management Systems) na primeru platforme Edmodo (Edmodo), kao i da li je to poboljšanje uslovljeno hibridnom tj. mešovitom nastavom. Istraživanje je fokusirano na četiri aspekta: (1) utvrditi stepen do kojeg su studenti ovladali specifičnim vokabularom primenom hibridnog pristupa u odnosu na tradicionalni pristup; (2) utvrditi da li i koliko se jezičko postignuće jezika struke poboljšalo primenom hibridnog pristupa u odnosu na korišćenje tradicionalnog pristupa kod učenja jezika struke; (3) ispitati stavove studenata o primeni informaciono-komunikacione tehnologije u učenju engleskog kao jezika struke; (4) utvrditi stavove o primeni hibridne nastave i platforme Edmodo u nastavi engleskog kao jezika struke nakon sprovedenog eksperimenta. U empirijsko istraživanje uključeni su studenti koji pohađaju nastavu Poslovnog engleskog jezika sa odseka Finansije i menadžment na Visokoj poslovnoj školi strukovnih studija iz Leskovca, starosti 21 ±2, koji su učili strani jezik od trećeg razreda osnovne škole i koji su se nalaze na B2 nivou poznavanja jezika prema Zajedničkom evropskom referentnom okviru za žive jezike. Istraživanjem je obuhvaćeno 80 ispitanika (44 osobe ženskog i 36 osobe muškog pola) . Za određivanje nivoa usvajanja nastavnog sadržaja u ovom istraživanju u obzir su uzeta dva vida jezičkog postignuća: ocena na finalnom merenju (1) kao i srednja vrednost ukupnog zbira poena na svakom pojedinačnom delu testa (2). U prvom delu istraživanja, analizirali smo koliko studenti eksperimentalne grupe poznaju širinu i dubinu vokabulara pre i posle primene hibridne nastave koristeći u tu svrhu testove višestrukog izbora, skalu poznavanja vokabulara i zadatka prepoznavanja vokabulara, i dobijene rezultate uporedili sa rezultatima kontrolne grupe. Rezultati su analizirani kvantitativno (putem T testa, Anove dvofaktorske analize, Efekta veličine i h2 testa) i kvalitativno. Rezultati istraživanja ukazali su da je eksperimentalna grupa znatno više napredovala u odnosu na kontrolnu grupu, što je dovelo do zaključka da se učenje jezika struke može poboljšati primenom hibridnog pristupa, i to primenom platforme Edmodo. U drugom delu istraživanja analizirali smo stavove studenata o primeni IKT u nastavi EJS putem anketnog upitnika kao i stavove i percepciju studenata eksperimentalne grupe o primeni hibridnog pristupa i platforme Edmodo u učenju. Dobijeni podaci upućuju da ispitanici obeju grupa imaju izrazito pozitivan stav prema primeni IKT u nastavi EJS, kao i to da ispitanici eksperimentalne grupe smatraju da se putem hibridnog pristupa povećava njihova efikasnost u učenju, autonomnost, kritičko razmišljanje, kao i motivacija za učenjem. Istraživanje je takođe ukazalo na prednosti koje hibridna nastava ima u odnosu na tradicionalnu u učenju EJS. Opšti zaključak jeste da se ovladavanje specifičnim vokabularom i jezičko postignuće jezika struke značajno povećava primenom hibridne nastave, kao i primenom platforme Edmodo u nastavi engleskog kao jezika struke. Značaj sprovedenog istraživanja ogleda se u predstavljanju jednog savremenog okvira za organizaciju i unapređenje nastave jezika struke na visokoškolskim institucijama u Republici Srbiji." ]
[ "The dissertation THE IMPROVEMENT OF ESP LEARNING THROUGH BLENDED LEARNING AND LEARNING MANAGEMENT SYSTEMS analyses the improvement of ESP learning by using the blended learning method and the Edmodo platform as a learning management system. The theme of this thesis and the conducted research can be classified into current topics of English Teaching Methodology and technology assisted language learning. The dissertation is intended to determine whether language achievement and mastering ESP vocabulary could be improved via Learning Management Systems and whether this is supported by using the blended learning method. The research is focused on four objectives (1) to determine the level to which the students master their ESP vocabulary by using the blended learning approach in comparison to the traditional one; (2) to determine whether and how language achievement in ESP can be improved by using the blended approach compared to traditional; (3) to examine the students’ attitudes towards the usage of ICT in ESP learning (4) to examine the students’ attitudes towards the usage of the blended learning approach and the Edmodo platform in ESP learning after completing the experiment. The empirical study included students who attended Business English classes at the Department of Finance and Management at the Higher Business School of Professional Studies in Leskovac, age 21 ± 2, who had studied English as a foreign language since the third grade of their primary school (B2 level of language proficiency according to the Common European Framework of Reference for Languages (CEFR)). The study included 80 participants (44 females and 36 males). To determine the level of the teaching material acquired by the students during the experiment, two aspects of language achievement were taken into consideration: the score at the final exam (1); the mean value of the total sum of points from each individual part of the test (2). In the first part of the study, based on examining the breadth and depth of vocabulary knowledge, we analysed the knowledge of the experimental group before and after the blended learning method application, through multiple-choice tests, a vocabulary knowledge scale and a vocabulary recognition task, and then we compared the obtained results with the ones of the control group. The results were analysed quantitatively (by paired samples test, two-factor ANOVA analysis, and the size effect and the chi-square test and qualitatively. The study showed that the results of the experimental group were significantly better in comparison to that of the control group, which led to the conclusion that ESP learning can be improved by both the application of the blended learning approach, and the application of the Edmodo platform. In the second part of the study we analysed the attitudes of the participants in both groups towards the use of ICT in ESP learning as well as the attitudes and perceptions of the participants in the experimental group towards the implementation of the blended learning approach and the Edmodo learning platform for ESP learning. The obtained results indicated that the participants in both groups have a very positive attitude towards the use of ICT in ESP learning. Also, the results of the experimental group showed that its participants find a blended approach useful in learning ESP contents, promoting their critical thinking and increasing their motivation. The research also pointed to the advantages of the blended learning courses over courses taught in a traditional way. The general conclusion is that mastering ESP vocabulary and language achievement are significantly improved when the blended learning method and the Edmodo platform are applied in ESP learning. The significance of this research can be seen as an attempt to present a modern framework for organizing and promoting ESP courses at higher education institutions in the Republic of Serbia." ]
application/pdf
sr
Универзитет у Крагујевцу, Филолошко-уметнички факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Крагујевцу
[ "engleski jezik struke", "hibridna nastava", "sistemi za upravljanje učenjem", "jezičko postignuće", "vokabular" ]
[ "English for Specific Purposes", "ESP vocabulary", "the blended learning approach", "the Edmodo platform", "learning management systems", "language achievement" ]
[ "Unapređenje učenja jezika struke putem hibridne nastave i sistema za upravljanje učenjem" ]
[ "The improvement of esp learning through blended learning and learning management systems" ]
doctoralThesis
[ "BY-NC-ND" ]
Благојевић, Савка; Марковић, Дејан; Мишковић-Луковић, Мирјана; Ђорђевић, Јасмина; Стојковић-Трајковић, Миљана; Унапређење учења језика струке путем хибридне наставе и система за управљање учењем; Унапређење учења језика струке путем хибридне наставе и система за управљање учењем;
[ "https://nardus.mpn.gov.rs/bitstream/id/50903/Disertacija.pdf", "https://nardus.mpn.gov.rs/bitstream/id/50904/Izvestaj_Miljana_Stojkovic_Trajkovic_FILUM.pdf", "http://nardus.mpn.gov.rs/bitstream/id/50903/Disertacija.pdf", "http://nardus.mpn.gov.rs/bitstream/id/50904/Izvestaj_Miljana_Stojkovic_Trajkovic_FILUM.pdf", "https://fedorakg.kg.ac.rs/fedora/get/o:955/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_9388" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
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[ "" ]
[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/8643
123456789-8643.pdf
yes
no
https://fedorani.ni.ac.rs/fedora/get/o:1402/bdef:Content/download
no
Analitički model za procenu dinamičke potrošnje aritmetičkih kola implementiranih na FPGA
[ "Jevtić, Milun" ]
[ "Litovski, Vančo", "Dokić, Branko", "Damnjanović, Milunka", "Petković, Predrag" ]
Jovanović, Bojan
2017-10-03T07:39:55
[ "2017-10-03T07:39:55", "2020-07-03T16:02:28" ]
2013-02-21
[ "http://eteze.ni.ac.rs/application/showtheses?thesesId=5289", "https://nardus.mpn.gov.rs/handle/123456789/8643", "https://fedorani.ni.ac.rs/fedora/get/o:1402/bdef:Content/download", "http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70052&RID=533471126" ]
[ "" ]
[ "During the past years the progress of silicon process technology marched on relentlessly. According to Moore’s law, silicon process technology continues improvement at an astonishing pace. Every 2 years the number of transistors that can be integrated on a single IC approximately doubles. The continued scaling of the CMOS technology has led us into the deep submicron regimes where design is not limited by the functionality on a chip but is constrained with its power consumption. Numerous portable battery-powered electronic devices with outstanding performances are the prove of previous statement. Starting from 180nm technologies, static power consumption due to leaky “off” transistors is now a non negligible source of power dissipation, even in running mode. Thus, the total power consumption (i.e. dynamic plus static power) has to be optimized instead of simply reducing dynamic power. The first part of this work is oriented toward the problems of power consumption (both static and dynamic) minimization techniques. The largest impact on power reduction can be achieved at the system level where architecture and algorithms are to be defined. Influencing power consumption without sacrificing system performances is becoming harder and harder at the lower levels of system design flow. Selecting the most power efficient algorithm out of many available requires a fast and accurate way to estimate the power consumption of any implementation. In this way, time-consuming low-level implementations of each possible design architecture will be avoided. Therefore, the second part of this thesis deals with high-level dynamic power estimation models of DSP-oriented (Digital Signal Processing) designs. This dissertation is the continuation of the work on power estimation models described in [Jev09] and presents the methodology for high-level logic power estimation which is based on the component’s structure and the analytical computation of the switching activity produced inside the component. Power estimation models are parametrized in terms of input signal statistics (mean, variance, autocorrelation) and operands’ word-lengths. The improvement of the existing model for ripple carry array multiplier switching activity (dynamic power) estimation is firstly presented. Unlike previous DBT (Dual-Bit Type) model, the TBT (Triple-Bit Type) model presented here takes into account nonlinearities in bit-level switching activities occurring at the multiplier output. It is experimentally confirmed that the model proposed in this thesis gives far better power estimations (four to five times) than the previous one. After that, the methodology for high-level logic power estimation of binary divider is presented. To the best of author’s knowledge no previous work focuses on high-level divider power estimation. In order to evaluate proposed models, DSP designs are implemented on Virtex II Pro FPGA device on XUP (Xilinx University Program) board and dynamic on-board power consumption is measured. Apart on-board dynamic power, as a reference for our models evaluation, XPower Analyzer tool within the Xilinx ISE software package is used. The mean relative errors of our high-level power estimation models are less than 10% which is very encouraging result, given a fact that the models have high-level nature. In addition to high accuracy, proposed methodology for dynamic power estimation is very fast. The power estimates are obtained in order of milliseconds." ]
application/pdf
sr
Универзитет у Нишу, Електронски факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Нишу
[ "Električna energija", "dinamička potrošnja", "aritmetička kola", "FPGA" ]
[ "" ]
[ "Analitički model za procenu dinamičke potrošnje aritmetičkih kola implementiranih na FPGA" ]
[ "" ]
doctoralThesis
[ "BY-NC-ND" ]
Јевтић, Милун; Литовски, Ванчо; Докић, Бранко; Дамњановић, Милунка; Петковић, Предраг; Јовановић, Бојан; Aналитички модел за процену динамичке потрошње аритметичких кола имплементираних на ФПГA; Aналитички модел за процену динамичке потрошње аритметичких кола имплементираних на ФПГA;
[ "http://nardus.mpn.gov.rs/bitstream/id/153538/Disertacija.pdf", "https://fedorani.ni.ac.rs/fedora/get/o:1402/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_8643" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/10507
123456789-10507.pdf
yes
no
https://fedorakg.kg.ac.rs/fedora/get/o:1007/bdef:Content/download
no
Digitalni dijalog kao reinženjering u sistemu hibridnog učenja
[ "Veljović, Alempije" ]
[ "Milošević, Danijela", "Papić, Miloš", "Radulović, Biljana" ]
Ranđelović, Momčilo B.
2018-12-26T15:03:12
[ "2018-12-26T15:03:12", "2020-07-03T15:21:59" ]
2018-09-25
[ "http://eteze.kg.ac.rs/application/showtheses?thesesId=6060", "https://nardus.mpn.gov.rs/handle/123456789/10507", "https://fedorakg.kg.ac.rs/fedora/get/o:1007/bdef:Content/download" ]
[ "REZIME Generacije učenika 21. veka odrastaju uz digitalne tehnologije. Digitalne uređaje kao što su mobilni telefoni, tablet i laptop računari oni koriste svakodnevno, u međusobnoj komunikcaciji, za zabavu, za prikupljanje raznih informacija, ali i za učenje. Protok informacija je daleko brži, a nastavnik i udžbenik odavno nisu jedini izvori školskog gradiva. U takvoj atmosferi su kreativnost na času i pažnja učenika prepušteni isključivo ličnoj inicijativi, kreativnosti i entuzijazmu nastavnika. Od produkata savremenih informacionih tehnologija se očekuje da u tom smislu unaprede neposrednu nastavu i prilagode je zahtevu vremena. Digitalni dijalog, kao relativno nov koncept podrške tradicionalnoj nastavi predstavlja jedno od mogućih rešenja. On upravo predstavlja koncept tehnološke podrške za ostvarivanje asimetričnog partnerstva, koje počiva na odgovarajućoj komunikaciji između učenika i nastavnika. Međutim, brojni eksperimenti i pojedinačna iskustva primene digitalnog dijaloga u nastavi, od uvođenja digitalnih klikera do interneta inteligentnih uređaja, govore da se njegovi puni efekti mogu očekivati tek nakon sprovedenog reinženjeringa procesa postojećeg sistema. Redizajniranje neposredne nastave implicira stvaranje novog sitema za učenje – hibridni sistem baziran na digitalnom dijalogu. Ovaj rad predstavlja jedno od istraživanja dometa digitalnog dijaloga u nastavi. Najpre su ispitivane mogućnosti za realizaciju digitalnog dijaloga u praksi: pedagoški, tehnički i bezbedonosni zahtevi. Na osnovu tih rezultata izrađen je konceptualni okvir za analizu i projektovanje procesa i postavljena osnova za razvoj novog, efikasnijeg sistema kroz reinženjering postojećeg sistema hibridnog učenja. U istraživanju su analiza i modelovanje obavljeni korišćenjem standarda IDEF0. Evaluacija rezultata je obavljena sprovođenjem eksperimentalnog istraživanja, merenjem efekata primene digitalnog dijaloga na dva odeljenja 3. razreda srednje elektrotehničke škole u Nišu, kroz tromesečni klasifikacioni period. Rezultati istraživanja su potvrdili početne hipoteze. Pokazalo se da savremene informacione tehnologije omogućavaju da se primenom BYOD koncepta formira informacioni sistem za digitalni dijalog u učionici. Takođe je dokazano da se primenom digitalnog dijaloga u nastavi ostvaruje znatno viši stepen intrakcije obrazovnih subjekata uz mogućnost da se istovremeno digitalno dokumentuje čitav nastavni proces u realnom vremenu." ]
[ "ABSTRACT Generations of 21st century students grow up with digital technologies. They use digital devices such as mobile phones, tablets and laptops everyday, in communication, for entertainment, for gathering various information, but also for learning. The flow of information is much faster, and the teacher and textbook for a long time are not the only sources of school material. In such an atmosphere, creativity is on the time and attention of students, left exclusively to personal initiative, creativity and enthusiasm of teachers. The products of modern information technologies are expected to improve immediate teaching in this respect and adapt them to the demand of time. Digital dialogue, as a relatively new concept of support for traditional teaching, is one of the possible solutions. It is precisely the concept of technological support for achieving an asymmetrical partnership, based on appropriate communication between students and teachers. However, numerous experiments and individual experiences of applying digital dialogue in teaching, from the introduction of digital clickers to the internet of things, say that its full effects can only be expected after a reengineering process of the existing system has been carried out. Redesigning immediate teaching implies the creation of a new learning environment - a hybrid system based on digital dialogue. This paper represents one of the research of the range of digital dialogue in teaching. First, the possibilities for realization of digital dialogue in practice, pedagogical, technical and security requirements were examined. On the basis of these results, a conceptual framework for the analysis and design of the process was developed and the basis for the development of a new, more efficient system was developed through the reengineering of the existing hybrid learning system. In the research, the analysis and modeling were performed using the IDEF0 standard. Evaluation of the results was carried out by conducting experimental research, measuring the effects of the application of digital dialogue in two departments of the third grade of the secondary electrical school in Nis through the three-month classification period. The results of the study were confirmed by the initial hypothesis. Modern information technology has proven to enable the use of the BYOD concept to form an information system for digital dialogue in the classroom. It has also been proven that by using digital dialogue in teaching, a significantly higher level of intra-educational subject is realized, while simultaneously digital documentation of the whole teaching process in real time." ]
application/pdf
sr
Универзитет у Крагујевцу, Факултет техничких наука, Чачак
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Крагујевцу
[ "digitalni dijalog", "reinženjering", "hibridno učenje", "interaktivna nastava" ]
[ "digital dialogue", "reengineering", "hybrid learning", "interactive teaching" ]
[ "Digitalni dijalog kao reinženjering u sistemu hibridnog učenja" ]
[ "" ]
doctoralThesis
[ "BY-NC-ND" ]
[ "https://nardus.mpn.gov.rs/bitstream/id/50574/Disertacija.pdf", "https://nardus.mpn.gov.rs/bitstream/id/50575/Momcilo_Randjelovic_FTN.pdf", "http://nardus.mpn.gov.rs/bitstream/id/50574/Disertacija.pdf", "http://nardus.mpn.gov.rs/bitstream/id/50575/Momcilo_Randjelovic_FTN.pdf", "https://fedorakg.kg.ac.rs/fedora/get/o:1007/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_10507" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/4785
123456789-4785.pdf
yes
no
http://nardus.mpn.gov.rs/bitstream/id/153534/Disertacija.pdf
no
Analiza parametara za procenu seizmičkog odgovora višespratnih armiranobetonskih okvira
Analysis of parameters for seismic response assessment of multy-storey reinforced concrete frames
[ "Lađinović, Đorđe" ]
[ "Folić, Radomir", "Brčić, Stanko", "Kovačević, Dušan", "Brujić, Zoran", "Lađinović, Đorđe" ]
Radujković, Aleksandra
2020-07-03T14:14:06
[ "2020-07-03T14:14:06" ]
2015-12-04
[ "https://nardus.mpn.gov.rs/handle/123456789/4785", "http://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija144767609938959.pdf?controlNumber=(BISIS)95695&fileName=144767609938959.pdf&id=4636&source=NaRDuS&language=sr", "http://www.cris.uns.ac.rs/record.jsf?recordId=95695&source=NaRDuS&language=sr", "http://www.cris.uns.ac.rs/DownloadFileServlet/IzvestajKomisije144308073220956.pdf?controlNumber=(BISIS)95695&fileName=144308073220956.pdf&id=4344&source=NaRDuS&language=sr" ]
[ "U radu su analizirani uticaji parametara: klase dukktilnosti, projektnog seizmičkog dejstva i spratnosti na seizmički odgovor AB okvira projektovanih prema evropskim normama EN 1992 - 1 i EN 1998 - 1.Odgovor konstrukcije, dobijen primenom nelinearnih statičkih i dinamičkim metoda, je razmatran na globalnom, spratnom i lokalnom nivou. Procena stanja je sprovedena pre svega direktnim poređenjem zahteva rotacije tetiva stubova i greda okvira sa kapacitetom za dva granična stanja prema EN 1998 - 3. Pored toga, upoređeni su zahtevi sa kapacitetom u pogledu duktilnosti krivina kritičnih poprečnih preseka i zahtevi odnosa međuspratnog pomeranja i spratne visine sa tipičnim vrednostima za očekivani nivo oštećenja konstrukcije." ]
[ "The paper analyzed influence of parameters: ductility class, design seismic actions and the number of story on seismic response of RC frames designed according to EN 1992-1 and EN 1998-1. Seismic response, obtained using nonlinear static and dinamic methods, at global, storey and local levels was discussed. Assessment was carried out primarly by direct comparison chord rotation RC frames columns and beams demands with a capacity of two limit states according to EN 1998-3. In addition, curvature ductility critical regions demands and capacitiy and inter storey drift demands and tipical values for expected level of structural damage, were compared." ]
sr (latin script)
Универзитет у Новом Саду, Факултет техничких наука
[ "info:eu-repo/grantAgreement/MESTD/Technological Development (TD or TR)/36043/RS//" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc/4.0/" ]
Универзитет у Новом Саду
[ "AB konstrukcije", "seizmičko inženjerstvo", "seizmički zahtev" ]
[ "RC structures", "seismic engineering", "seismic demands" ]
[ "Analiza parametara za procenu seizmičkog odgovora višespratnih armiranobetonskih okvira", "Analysis of parameters for seismic response assessment of multy-storey reinforced concrete frames" ]
[ "" ]
doctoralThesis
[ "BY-NC" ]
Лађиновић Ђорђе; Фолић Радомир; Брчић Станко; Ковачевић Душан; Брујић Зоран; Лађиновић Ђорђе; Радујковић Aлександра; Aнализа параметара за процену сеизмичког одговора вишеспратних армиранобетонских оквира; Aнализа параметара за процену сеизмичког одговора вишеспратних армиранобетонских оквира;
[ "https://nardus.mpn.gov.rs/bitstream/id/43658/IzvestajKomisije366.pdf", "http://nardus.mpn.gov.rs/bitstream/id/43658/IzvestajKomisije366.pdf", "http://nardus.mpn.gov.rs/bitstream/id/153534/Disertacija.pdf", "http://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija144767609938959.pdf?controlNumber=(BISIS)95695&fileName=144767609938959.pdf&id=4636&source=NaRDuS&language=sr" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_4785" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/3689
123456789-3689.pdf
yes
no
https://fedorakg.kg.ac.rs/fedora/get/o:214/bdef:Content/download
yes
Prognostički faktori značajni za uspeh hirurškog lečenja tempanoskleroze
[ "Đerić, Dragoslava" ]
[ "Stanković, Milan", "Živić, Ljubica", "Baletić, Nenad", "Erdevički, Ljiljana" ]
Milojević, Milanko
2016-01-05T13:09:49
[ "2016-01-05T13:09:49", "2020-07-03T15:19:19" ]
2013
[ "https://nardus.mpn.gov.rs/handle/123456789/3689", "http://eteze.kg.ac.rs/application/showtheses?thesesId=302", "https://fedorakg.kg.ac.rs/fedora/get/o:214/bdef:Content/download" ]
[ "" ]
[ "" ]
application/pdf
sr
Универзитет у Крагујевцу, Факултет медицинских наука
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc/4.0/" ]
Универзитет у Крагујевцу
[ "Tempanoskleroza" ]
[ "" ]
[ "Prognostički faktori značajni za uspeh hirurškog lečenja tempanoskleroze" ]
[ "" ]
doctoralThesis
[ "BY-NC" ]
Ђерић, Драгослава; Ердевички, Љиљана; Станковић, Милан; Балетић, Ненад; Живић, Љубица; Милојевић, Миланко; Прогностички фактори значајни за успех хируршког лечења темпаносклерозе; Прогностички фактори значајни за успех хируршког лечења темпаносклерозе;
[ "http://nardus.mpn.gov.rs/bitstream/id/153535/Disertacija.pdf", "https://fedorakg.kg.ac.rs/fedora/get/o:214/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_3689" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/8644
123456789-8644.pdf
yes
no
https://fedorani.ni.ac.rs/fedora/get/o:1403/bdef:Content/download
no
Design of scalar compandor for medium bit rate using spline approximations
[ "Perić, Zoran" ]
[ "Stefanović, Mihajlo", "Đurović, Željko", "Stanković, Miomir", "Jovanović, Aleksandra" ]
Velimirović, Lazar Z.
2017-10-03T07:39:55
[ "2017-10-03T07:39:55", "2020-07-03T16:02:29" ]
2013-04-26
[ "http://eteze.ni.ac.rs/application/showtheses?thesesId=5290", "https://nardus.mpn.gov.rs/handle/123456789/8644", "https://fedorani.ni.ac.rs/fedora/get/o:1403/bdef:Content/download", "http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70052&RID=533490838" ]
[ "" ]
[ "In this doctoral thesis, firstly the general characteristics of the signal and scalar quantizers, as well as the procedure of signal discretization, are described, and then the model of scalar compandor is shown. By linearization and approximation of the optimal compressor function, the simplification of the compandor model is done toward its simpler realization. The validity of compandor design based on linearized compressor function and approximative spline functions of the first and second order is confirmed in this thesis. Using spline functions, the optimal compressor function can be well approximated. Therefore, in this PhD thesis, special attention is paid to scalar compandor design by using first and second order spline functions. A detailed analysis of the proposed compandor models for the input signals modelled by Laplacian and Gaussian probability density function is done. Also, it is shown that by the proposed quantizer model, signal quality that is very close to signal quality of the optimal companding quantizer, is achieved. The analysis of the proposed compandor model allows designers to gain complete insight on the compandor technique significance, the support region, the number of segments, the number of quantization levels and the types of the input signals on the compandor performances, and also to design the optimal compandor model for the desired parameters." ]
application/pdf
sr
Универзитет у Нишу, Електронски факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Нишу
[ "skalarni kompandor", "kompresorska funkcija", "linearizacija", "skalarna kvantizacija", "optimizacija amplitudskog opsega kompandora", "splajn aproksimacije", "prošireno Hafmanovo kodovanje" ]
[ "" ]
[ "Design of scalar compandor for medium bit rate using spline approximations" ]
[ "" ]
doctoralThesis
[ "BY-NC-ND" ]
Перић, Зоран; Стефановић, Михајло; Ђуровић, Жељко; Станковић, Миомир; Јовановић, Aлександра; Велимировић, Лазар З.;
[ "http://nardus.mpn.gov.rs/bitstream/id/153536/Disertacija.pdf", "https://fedorani.ni.ac.rs/fedora/get/o:1403/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_8644" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/8646
123456789-8646.pdf
yes
no
https://fedorani.ni.ac.rs/fedora/get/o:1405/bdef:Content/download
no
Sistem za testiranje uređaja za merenje kvaliteta električne energije baziran na primeni virtuelne instrumentacije
[ "Denić, Dragan" ]
[ "" ]
Simić, Milan M.
2017-10-03T07:39:56
[ "2017-10-03T07:39:56", "2020-07-03T16:02:31" ]
2013-12-26
[ "https://nardus.mpn.gov.rs/handle/123456789/8646", "http://eteze.ni.ac.rs/application/showtheses?thesesId=5295", "https://fedorani.ni.ac.rs/fedora/get/o:1405/bdef:Content/download", "http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70052&RID=533493654" ]
[ "" ]
[ "" ]
application/pdf
sr
Универзитет у Нишу, Електронски факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Нишу
[ "Električna energija - Merenje kvaliteta" ]
[ "" ]
[ "Sistem za testiranje uređaja za merenje kvaliteta električne energije baziran na primeni virtuelne instrumentacije" ]
[ "" ]
doctoralThesis
[ "BY-NC-ND" ]
Денић, Драган; Симић, Милан М.; Систем за тестирање уређаја за мерење квалитета електричне енергије базиран на примени виртуелне инструментације; Систем за тестирање уређаја за мерење квалитета електричне енергије базиран на примени виртуелне инструментације;
[ "http://nardus.mpn.gov.rs/bitstream/id/153537/Disertacija.pdf", "https://fedorani.ni.ac.rs/fedora/get/o:1405/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_8646" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/21719
123456789-21719.pdf
yes
yes
no
Uticaj atributa restoraterske usluge na ocene zadovoljstva gostiju na sajtu Tripadvisor
[ "Knežević, Miroslav" ]
[ "Brdar, Ivana", "Milićević, Snežana" ]
Živadinović, Bojan
2023-10-03T12:01:23
[ "2023-10-03T12:01:23" ]
2023-09-14
[ "https://singipedia.singidunum.ac.rs/izdanje/44400-uticaj-atributa-restoraterske-usluge-na-ocene-zadovoljstva-gostiju-na-sajtu-tripadvisor", "https://nardus.mpn.gov.rs/handle/123456789/21719" ]
[ "" ]
[ "" ]
Универзитет Сингидунум, Студије при универзитету
[ "" ]
[ "openAccess" ]
[ "" ]
Универзитет Сингидунум
[ "" ]
[ "" ]
[ "Uticaj atributa restoraterske usluge na ocene zadovoljstva gostiju na sajtu Tripadvisor" ]
[ "" ]
doctoralThesis
[ "ARR" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/153528/bitstream_153528.pdf", "http://nardus.mpn.gov.rs/bitstream/id/153527/bitstream_153527.pdf" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_21719" ]
sr
[ "Menadžment i biznis" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/3839
123456789-3839.pdf
yes
no
https://fedorakg.kg.ac.rs/fedora/get/o:500/bdef:Content/download
no
Dekonstrukcija identiteta postmodernog subjekta u Njujorškoj trilogiji Pola Ostera i Antropološkoj trilogiji Borislava Pekića
Identity Deconstruction of the Postmodern Subject in Paul Auster’s The New York Trilogy and Borislav Pekić’s Anthropological Trilogy
[ "Bošković, Dragan" ]
[ "Nastić, Radmila", "Đorić, Biljana", "Bubanja, Nikola" ]
Lojanica, Marija
2016-01-05T13:17:41
[ "2016-01-05T13:17:41", "2020-07-03T15:23:12" ]
2015-10-08
[ "http://eteze.kg.ac.rs/application/showtheses?thesesId=2068", "https://nardus.mpn.gov.rs/handle/123456789/3839", "https://fedorakg.kg.ac.rs/fedora/get/o:500/bdef:Content/download" ]
[ "U disertaciji Dekonstrukcija identiteta postmodernog subjekta u Njujorškoj trilogiji Pola Ostera i Antropološkoj trilogiji Borislava Pekića, primenom analitičko-sintetičke, komparativne i dekonstruktivističke metode, razmatrali smo formalne i idejno-tematske postavke pomenutih trilogija, koje nauka o književnosti do sada nije dovodila u direktnu, bilo teoretsko-idejnu, bilo formalno-žanrovsku vezu, a njihov odnos, u književno-teorijskom diskursu, nije sistematično i naučno-utemeljeno ispitivan. U uvodnom delu radu, ponudili smo razmatranje pojmova subjektivitet i identitet, te razvojnog luka ontološke misli od kartezijanskog do takozvanog strukturalističkog preokreta. Ovakva analiza rezultirala je sledećim zaključkom: koncept identiteta humanog subjekta inicijalno je uspostavljen kao apsolutno racionalizovana, autonomna i samoodrživa kategorija, čije utemeljenje počiva u strukturama koje su joj imanentne. Međutim, ontološke teorije istovremeno postuliraju i nužnost postojanja eksternih autoriteta koji omogućavaju konstitusanje i održanje sopstva. U tom smislu, neosnovano bi bilo tvrditi da su novovekovne, prosvetiteljske i klasično-idealističke koncepcije sopstva ukazivale na potpunu autonomnost subjekta. No, iako su mnogi od stavova koje su postulirali teoretičari od Dekarta do strukturalista prevaziđeni, pa čak i fundamentalno osporeni, nepobitna je činjenica da savremene teorije subjektiviteteta ne samo nastavljaju niz započet kartezijanskim prevratom, već i ulaze u direktan dijalog sa hipotezama svojih prethodnika, a u izvesnoj meri, njima su inspirisane ili anticipirane." ]
[ "" ]
application/pdf
sr
Универзитет у Крагујевцу, Филолошко-уметнички факултет
[ "info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/178018/RS//" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc/4.0/" ]
Универзитет у Крагујевцу
[ "Auster", "Paul", "1948- subjektivitet", "identitet", "postmodernizam", "postkulturalizam" ]
[ "Pekić", "Borislav", "1930-1992" ]
[ "Dekonstrukcija identiteta postmodernog subjekta u Njujorškoj trilogiji Pola Ostera i Antropološkoj trilogiji Borislava Pekića", "Identity Deconstruction of the Postmodern Subject in Paul Auster’s The New York Trilogy and Borislav Pekić’s Anthropological Trilogy" ]
[ "" ]
doctoralThesis
[ "BY-NC" ]
Бошковић, Драган; Настић, Радмила; Ђорић, Биљана; Бубања, Никола; Лојаница, Марија; Деконструкција идентитета постмодерног субјекта у Њујоршкој трилогији Пола Остера и Aнтрополошкој трилогији Борислава Пекића; Деконструкција идентитета постмодерног субјекта у Њујоршкој трилогији Пола Остера и Aнтрополошкој трилогији Борислава Пекића;
[ "http://nardus.mpn.gov.rs/bitstream/id/50724/marija_lojanica_24072015.pdf", "http://nardus.mpn.gov.rs/bitstream/id/50723/Disertacija.pdf", "https://nardus.mpn.gov.rs/bitstream/id/50724/marija_lojanica_24072015.pdf", "https://nardus.mpn.gov.rs/bitstream/id/50723/Disertacija.pdf", "https://fedorakg.kg.ac.rs/fedora/get/o:500/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_3839" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/8992
123456789-8992.pdf
yes
no
https://fedorakg.kg.ac.rs/fedora/get/o:858/bdef:Content/download
no
Nacija, subjekt, tekst (književnost egzila i postjugoslovenski kulturni prostor)
Nation, Subject and Text (the Literature of Exile and the Post-Yugoslav Literary and Cultural Landscape)
[ "Rosić Ilić, Tatjana" ]
[ "Bošković, Dragan", "Brajović, Tihomir", "Đurić, Dubravka", "Melić, Katarina" ]
Đoković, Nikola
2017-12-19T09:02:57
[ "2017-12-19T09:02:57", "2020-07-03T15:23:49" ]
2017-09-25
[ "http://eteze.kg.ac.rs/application/showtheses?thesesId=5434", "https://nardus.mpn.gov.rs/handle/123456789/8992", "https://fedorakg.kg.ac.rs/fedora/get/o:858/bdef:Content/download" ]
[ "Овај рад бави се релацијама и односима дискурзивних/текстуалних типологија који улазе у процес конституисања нација – насталих насилним распадом некада јединственог југословенског историјског (политичког и културног) простора – и субјект-позиција унутрашњег/спољашњег егзила, који се опиру овом тоталитарном конституисању (или му, са друге стране, подлежу). Као парадигматични примери анализе типологије/топологије изгнанстава из још увек доминантног великог наратива Нације, користе се романи Владимира Арсенијевића (U potpalublju), Дубравке Угрешић (Muzej bezuvjetne predaje), Давида Албахарија (Sneţni ĉovek) и Александра Хемона (Nowhere man), који преплићу лично, аутобиографско сведочење, са начинима фикционализације и наративизације позиције аутора/ауторке као присилног и/или добровољног егзиланта/егзиланткиње. Унутрашња позиција егзила у роману U potpalublju, преиспитује се кроз однос наратора са унутрашњом микро-заједницом пријатеља која је у сталном осипању услед мобилизације за српске националистичке ратове, насилног слања на фронт и чак добровољних опредељења појединих пријатеља да учествују у освајачком рату Србије против првих суседа. Из позиције сведока-саучесника преиспитује се лични степен трпељивости према страдању, као што се и скрутинизује етичка одговорност као и не-могућност одупирања у тачки потпуне унутрашње изолације. Позиција псеудо-религијског ескапизма се у једном тренутку спаја са доминантном позитивном сублимацијом и естетизацијом рата и масовних злочина. Тако се заједница унутрашњег егзила, између осталог, осипа зато што не може да артикулише сопствени консензуални, морални, анти-ратни императив непристајања на приклањање пропаганди доминантне националистичке заједнице. У Muzeju bezuvjetne predaje стратегија грађе романа као музеолошког експоната доводи субјект-позицију „колекционарке― у стање стално грозничавог прикупљања меморабилија и доказа личног породичног као и заједничког конфедеративног живота социјалистичке заједнице. Приватна колекција породичне архиве (ауто-биографске садржине) претвара се у архивску студију ретуширања и оживљавања детаља из онога што је упамћено и, са друге стране, заборављено или потпуно первертирано. Носталгично-меланхолична позиција сабирачице кичастог „шкарта― одбачених предмета, трансформише читаву архиву у амалгам реконструисаног памћења. Мнемотехнолошки залог памћења тако постаје поље борбе за одређену врсту етичко-естетичког императива против конфискације памћења диригованим заборавом (уз снажно полемисање са позицијом културализације и естетизације маскулино-шовинистичког насиља). Sneţni ĉovek Давида Албахарија проблематизује перспективу тотално изолованог али строго логоцентризованог дискурса „субалетна― у привидно тренутном а заправо трајном егзилу. Симболички испражњени субјект прати се кроз врло дисоцирану, репетитивну структуру романа, који у духу постструктурализма разграђује сопствено логоцентрично „средиште― и изнова га успоставља. Ова осцилација наративног „клатна―, поларизација присуства и одсуства – одсутног присуства – одвија се кроз умножавање и диференцијацију деридијанских „немих― трагова текста-сведочанства услед симултаног декомпоновања државног суверенитета (бивше државе) и субјект-позиције која се распада „изнутра―. Ова постмодернистичка клопка текста као структуре „левка―, који се пише услед негирања процеса писања и упркос њему, док фикционализовани субјект варљиво покушава да санира последице личног самоисписивања у трауматичном ексцесу опсесивних реитерација – заправо води деридијанској несводивој разлици између текста и гласа, текста и „говора ћутања― као места сублимиране трауме. Распадање „суверенитета― говорне инстанце немо говори, на метафоричан и метонимијски начин, логиком прећуткивања и потискивања, о насиљу суверено-етничког самоизрицања и „само-опредељења―, односно коинцидира са фантомализованом перспективом потпуног идентитетског стапања бивше-државног и садашњег субјектовог постојања које је такође под знаком питања услед изостанка ове неименоване надинстанце. Националистичко, као и са друге стране, неоколонијално наслеђе, функционише овде све време као прећутани интерлокутор. Nowhere man представља позицију субјекта егзила укрштену са детаљима из личне биографије самог Александра Хемона који су „позајмљени― насловном протагонисти, Јозефу Пронеку. Делимично на типичан постмодернистички начин кроз ефекат двојништа, делимично пак кроз проблематизовање пост- трауматског афективног умножавања позиција сведочења трауме, кроз мултиперспективну наративну позицију и дезилузионистичко разбијање имагинарног „зида― према читаоцу – изграђује се психогеографска, укрштена афективна мапа трауматичног сведочења места изгнанстава. Од читаоца се изнова захтева позиција емпатичке узнемирености, као и претресања и инспекције историјских чињеница прогона и етничких чишћења, упркос трауматици тог увида, а у корист императива са-знања и сведочења. Трауматска „трансверзала―, која прати пут Јозефа Пронека (у стилу „романа о одрастању―) од предратног Сарајева (пре српске опсаде) преко Украјине и Кијева до С.А.Д. Чикага (као „коначне―, данашње егзилантске дестинације самог Александра Хемона), осцилује на начин петље и враћања/реитерације местима зазора и терора. Билингвална позиција ауторства Александра Хемона, додатно проблематизује и саму нужност сведочења постратне трауме на „матерњем― језику, као што превођење и оно што оно укључује/искључује постаје једна од повлашћених тема услед идентитетског посвајања егзиланта у хомогеним заједницама које свој статус потврђују и потпуном насилном, кривотвореном еквиваленцијом између етније,нације, језика и писма. На крају, доводи се у питање и однос према доминантним патрилинеарним, патријахално-националистичким формама „фикционализације― заједништва путем „измишљене традиције― на коју се националистичка заједница увек изнова позива. Литерарна фикционализација стога представља један облик могућег другачијег имагинирања заједништва који се опире доминантним националистичким сврставајућим имагинирањима." ]
[ "This thesis centers on inter-relations of discursive/ textual typologies which constitute national states established after the violent tearing apart of a formerly united Yugoslav historical (political and cultural) landscape as well as the newly established subjectpositions of the inner/internal exile resisting the totalitarian process of re-constitution (or on the other hand conforming to it). The relevant examples of the analysis of the typology/ topology of the detachment from still prevailing and dominant Grand National narrative, are four selected novels: In the Hold by Vladimir Arsenijevic, The Museum of Unconditional Surrender by Dubravka Ugresic, Snow man by David Albahari and Nowhere Man by Aleksandar Hemon. In these novels, specific forms of personal, biographical testimonies are intertwined with different modes of fictionalization and narrativization of the authors‘ positions as those of compulsory and/or voluntary exiles. The position of inner exile in In the Hold questions the narrator‘s relations towards an inner micro-community of friends which is ever dispersing and decreasing because most of them were mobilized for Serbian nationalist war (some of them by force, others willingly taking part in Serbian aggression against its near neighbours). The position of a witness-accomplice allows an examination of a personal level of tolerance for suffering as well as scrutinizing one‘s ethical responsibility and also the impossibility of resistance in the situation of an utmost isolation. The prevailing mode of pseudo-religious escapism at one moment merges with the dominant positive sublimation and the aestheticization of violence and war crimes. Therefore, the community of inner exiles dissipates, because it cannot articulate its consensual, ethical, anti-war imperative of disconsent. In The Museum od Unconditional Surrender, the strategy of novel structured as a museological exhibit (artefact) transforms the narrator into a figure of a female collector. The condition is that of permanent feverish collecting of memorabilia and pieces of evidence of family and communal life in a former socialist confederative background which was violently interrupted. The private collection of a family archive (with its autobiographical contents) becomes an archive study of retouching and reviving the common (communal) collective memory. The nostalgic-melancholic collection of kitsch 'rejects', that is, rejected items, transforms the whole archive into an amalgam of memories re-constructed. Mnemotechnical photographic strategy of memory re-collection thus becomes the battlefield for a certain ethical and aesthetical impetus directed against the confiscation of memory imposed by an orchestrated oblivion. Using the technique of essayistic comments and footnotes, Ugresic also provides a strong polemical discourse, arguing with the position od culturalization and aesthetization of masculino-chauvinistic, nationalistic violence. Snow Man by David Albahari problematizes the perspective of a completely isolated (but rigidly logocentric) discourse of the 'subaltern'. The oblivious subject of exile reveals his position in a dissociated, repetitive manner of the novel structure which, in a poststructuralistic mode, undermines its own logocentric 'core'. The opposition between the presence and absence – the absent presence – is achieved by means of multiplication and differentiation of Derridian silent traces. The discourse structure serves in itself as a testimony of a symbiotic de-composing which simultaneously incorporates the issues of sovereign state and a subject-position implied within this narrative of sovereignty. This postmodern textual-trap in the 'funnel' mode writes itself precisely because of and in spite of its state of denial while the fictionalized subject is deceptively trying to cope with the consequences of introspective 'selfwriting'. It leads to a Derridean irreducable difference between the text and the speech act, that is the text and the speaking through remaining silent. The disintegration of the speech act 'sovereignity' voices itself in a manner of silent oblivion, by the logic of the supressed and inarticulated violence of the ethnic sovereignty haunting the scene of exile. Nationalistic perspective merged with neocolonial heritage functions as a supressed split interlocutor. Nowhere Man introduces the position of an exile subject intertwined with personal details from the biography of the author, Aleksandar Hemon, which are 'borrowed' to the main protagonist, Jozef Pronek. The effect of doubling identity functions as a symptom of a post-traumatic stress disorder which leads further to affective spectral multiplication of a testifying position of the historical trauma. The multiperspective narrative position triggers dis-illusionistic crossing an imaginary boundary toward the reader who is in some cases implied in the text as another witness. Thus, a supposedly engaged reader can trace the constructed psychogeographic, overlapping affective mapping of traumatic testimonies, embracing the position of emphatic unsettlement, dealing with the memory of the places marked by exile and persecution which are a part of Josef Pronek‘s life path. Resembling the tradition of bildungsroman, the memory loop starts unraveling from the focal persective of the narrator‘s memories of pre-war Sarajevo (before the Serbian siege), Ukraine and Kiev, to the US (Chicago being the 'final' exile destination of Aleksandar Hemon himself). Hemon‘s bilingual position additionally problematizes the very necessity of testifying the war trauma in his 'mother tongue'. On the other hand, the process of translation and what it includes/excludes becomes one of the essential themes due to exile‘s identity appropriation by (or assimilation within) homogenous communities. The total appropriation of the exile‘s complex, bilingual language situation within the given social symbolic order is achieved through violent, falsified equivalence between the ethnicity, language and writing – which constitute(s) the nation-belonging. Eventually, this thesis questions the inter-relation between the dominant patrilineal and patriarchal-nationalistic forms of fictionalization of being-together forming the comm-unity. It happens by means of invented tradition which the nationalist community always already reiterates/ evokes. Therefore, literary fictionalization represents different writing strategies of imagining community which opposes to dominant nationalistic consensual imagining." ]
application/pdf
sr
Универзитет у Крагујевцу, Филолошко-уметнички факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Крагујевцу
[ "tekst", "nacija", "nacionalizam", "tipovi diskursa", "tipologija subjekt-pozicija svedočenja egzila (u egzilu)", "odnos jezik:govor", "prevod", "postjugoslovenski kulturni prostor" ]
[ "text", "nation", "nationalism", "types of discourse", "the tipology of subjectpositions of testifying the exile (in exile)", "language-speech relation", "translation", "post- Yugoslav cultural landscape" ]
[ "Nacija, subjekt, tekst (književnost egzila i postjugoslovenski kulturni prostor)" ]
[ "Nation, Subject and Text (the Literature of Exile and the Post-Yugoslav Literary and Cultural Landscape)" ]
doctoralThesis
[ "BY-NC-ND" ]
Росић Илић, Татјана; Бошковић, Драган; Брајовић, Тихомир; Ђурић, Дубравка; Мелић, Катарина; Ђоковић, Никола; Нација, субјект, текст (књижевност егзила и постјугословенски културни простор); Нација, субјект, текст (књижевност егзила и постјугословенски културни простор);
[ "http://nardus.mpn.gov.rs/bitstream/id/50875/Disertacija.pdf", "http://nardus.mpn.gov.rs/bitstream/id/50876/izvestaj_nikola_djokovic.pdf", "https://nardus.mpn.gov.rs/bitstream/id/50876/izvestaj_nikola_djokovic.pdf", "https://nardus.mpn.gov.rs/bitstream/id/50875/Disertacija.pdf", "https://fedorakg.kg.ac.rs/fedora/get/o:858/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_8992" ]
[ "" ]
[ "" ]
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https://nardus.mpn.gov.rs/handle/123456789/8466
123456789-8466.pdf
yes
no
https://fedorani.ni.ac.rs/fedora/get/o:1387/bdef:Content/download
no
Razvoj i primena OLAP tehnologije za poslovno odlučivanje
[ "Milovanović, Slavoljub" ]
[ "Stoimenov, Leonid", "Radović, Ognjen" ]
Stanković, Jovica M.
2017-07-28T14:36:41
[ "2017-07-28T14:36:41", "2020-07-03T16:01:06" ]
2017-06-05
[ "https://nardus.mpn.gov.rs/handle/123456789/8466", "http://eteze.ni.ac.rs/application/showtheses?thesesId=5157", "https://fedorani.ni.ac.rs/fedora/get/o:1387/bdef:Content/download", "http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70052&RID=533899414" ]
[ "" ]
[ "The dynamic buisiness environment in which modern enterprises operate iz very complex, conditioned by tough competition and many challenges. Continuous operation in such conditions is based on the appropriate decisions. Managers need right information at the right time and the right place, presented in a way that is best suited to make right and timely decisions and, thereafter, taking appropriate action. ..." ]
application/pdf
sr
Универзитет у Нишу, Економски факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Нишу
[ "poslovna inteligencija", "OLAP tehnologije", "podrška poslovnom odlučivanju", "informacione tehnologije", "informacioni sistemi" ]
[ "Buisiness intelligence", "OLAP technologies", "Buisiness Decision Support", "Information technologies", "Information systems" ]
[ "Razvoj i primena OLAP tehnologije za poslovno odlučivanje" ]
[ "" ]
doctoralThesis
[ "BY-NC-ND" ]
Миловановић, Славољуб; Стоименов, Леонид; Радовић, Огњен; Станковић, Јовица М.; Развој и примена ОЛAП технологије за пословно одлучивање; Развој и примена ОЛAП технологије за пословно одлучивање;
[ "https://nardus.mpn.gov.rs/bitstream/id/52035/Izv_UNI_Jovica_M_Stankovic_2017-5.pdf", "http://nardus.mpn.gov.rs/bitstream/id/52034/Disertacija.pdf", "http://nardus.mpn.gov.rs/bitstream/id/52035/Izv_UNI_Jovica_M_Stankovic_2017-5.pdf", "https://nardus.mpn.gov.rs/bitstream/id/52034/Disertacija.pdf", "https://fedorani.ni.ac.rs/fedora/get/o:1387/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_8466" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
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https://nardus.mpn.gov.rs/handle/123456789/18894
123456789-18894.pdf
yes
no
https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija163411749548196.pdf?controlNumber=(BISIS)118279&fileName=163411749548196.pdf&id=18589&source=NaRDuS&language=sr
no
Primena beskontaktnih metoda za 3D digitalizaciju skulpture i ugradnja zaštite od zloupotrebe u 3D virtuelni model
Application of Non-Contact Methods for 3D Digitization of Sculpture and Watermark Embedding for Protecting a 3D Virtual Model from Abuse
[ "Obradović, Ratko", "Popkonstantinović, Branislav" ]
[ "Ivetić, Dragan", "Budak, Igor", "Stojaković, Vesna", "Obradović, Ratko", "Popkonstantinović, Branislav" ]
Vasiljević, Ivana
2022-01-17T12:52:15
[ "2022-01-17T12:52:15" ]
2021-12-27
[ "https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija163411749548196.pdf?controlNumber=(BISIS)118279&fileName=163411749548196.pdf&id=18589&source=NaRDuS&language=sr", "https://www.cris.uns.ac.rs/record.jsf?recordId=118279&source=NaRDuS&language=sr", "https://www.cris.uns.ac.rs/DownloadFileServlet/IzvestajKomisije163411750885376.pdf?controlNumber=(BISIS)118279&fileName=163411750885376.pdf&id=18590&source=NaRDuS&language=sr", "https://nardus.mpn.gov.rs/handle/123456789/18894" ]
[ "Ovo istraživanje ima za cilj kreiranje pristupa za zaštitu virtuelnih 3D modela od zloupotrebe dostupnih širokom auditorijumu na internetu. Pristup predložen u istraživanju je primenjen na skulpturi, izabranom objektu od istorijskog značaja. Zasniva se na 3D digitalizaciji skulpture koja je izmenjena dodavanjem lokalnih detalja od gline, a koje je predložio vajar i na deljenju na internetu 3D virtuelnog modela dobijenog digitalizacijom skulpture sa ugrađenim zaštitnim elementom. Detalji od gline ugrađeni u skulpturu su asimetrični i diskretni da budu neprimetni prosečnom posmatraču. Originalna skulptura je takođe 3D digitalizovana i generisan je njen 3D model. Dobijeni 3D modeli su upoređeni i izmereno je odstupanje geometrije kako bi se utvrdilo u kojoj meri je ugrađeni zaštitni element neprimetan za prosečnog posmatrača, ali i da se taj element može detektovati i po potrebi ukloniti sa 3D modela sa ugrađenom zaštitom." ]
[ "This research aims to suggest an approach for protecting virtual 3D models from abuse while making them available on the Internet. The proposed approach was applied to a sculpture, an object of cultural heritage. It is based on the digitization of the sculpture altered by adding local clay details proposed by the sculptor and on sharing on the Internet a 3D model obtained by digitizing the sculpture with a built-in error. The clay details embedded in the sculpture are asymmetrical and discreet to be unnoticeable to an average observer. The original sculpture was also digitized and its 3D model created. The obtained 3D models were compared and the geometry deviation was measured to determine that the embedded error was invisible to an average observer and that the built-in error can be extracted." ]
sr (latin script)
Универзитет у Новом Саду, Факултет техничких наука
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Новом Саду
[ "digitalizacija", "autorska prava", "3D virtuelni model", "skulptura", "kulturno nasleđe", "watermark", "fotogrametrija", "3D digitalizacija", "vizuelna percepcija" ]
[ "digitization", "copyright", "3D virtual model", "sculpture", "cultural heritage", "watermark", "photogrammetry", "3D digitization", "visual perception" ]
[ "Primena beskontaktnih metoda za 3D digitalizaciju skulpture i ugradnja zaštite od zloupotrebe u 3D virtuelni model" ]
[ "Application of Non-Contact Methods for 3D Digitization of Sculpture and Watermark Embedding for Protecting a 3D Virtual Model from Abuse" ]
doctoralThesis
[ "BY-NC-ND" ]
Попконстантиновић, Бранислав; Обрадовић, Ратко; Стојаковић, Весна; Попконстантиновић, Бранислав; Обрадовић, Ратко; Иветић, Драган; Будак, Игор; Васиљевић, Ивана; Примена бесконтактних метода за 3Д дигитализацију скулптуре и уградња заштите од злоупотребе у 3Д виртуелни модел; Примена бесконтактних метода за 3Д дигитализацију скулптуре и уградња заштите од злоупотребе у 3Д виртуелни модел;
[ "http://nardus.mpn.gov.rs/bitstream/id/141885/Disertacija_12036.pdf", "http://nardus.mpn.gov.rs/bitstream/id/141886/Izvestaj_komisije_12036.pdf", "https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija163411749548196.pdf?controlNumber=(BISIS)118279&fileName=163411749548196.pdf&id=18589&source=NaRDuS&language=sr" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_18894" ]
[ "" ]
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https://nardus.mpn.gov.rs/handle/123456789/21543
123456789-21543.pdf
yes
no
https://fedorabg.bg.ac.rs/fedora/get/o:30640/bdef:Content/download
no
Ontogenija i filogenetski odnosi vrsta roda Niphargus Schiödte, 1947 (Crustacea: Amphipoda: Niphargidae) sa područja Srbije
Ontogeny and phylogenetic relationships of the species of the genus Niphargus Schiödte, 1947 (Crustacea: Amphipoda: Niphargus) from the territory of Srbija
[ "Tomić, Vladimir" ]
[ "Miličić, Dragana", "Dudić, Boris", "Đikanović, Vesna", "Ilić, Bojan" ]
Petković, Matija
2023-09-06T10:58:11
[ "2023-09-06T10:58:11" ]
2023-06-10
[ "https://uvidok.rcub.bg.ac.rs/bitstream/handle/123456789/5246/Referat.pdf", "https://eteze.bg.ac.rs/application/showtheses?thesesId=9216", "https://fedorabg.bg.ac.rs/fedora/get/o:30640/bdef:Content/download", "https://plus.cobiss.net/cobiss/sr/sr/bib/116296457", "https://nardus.mpn.gov.rs/handle/123456789/21543" ]
[ "Pored brojnih pokušaja i informacija dobijenih analizom morfoloških karakteristika i metodama molekularne taksonomije jedan od najbrojnijih rodova slatkovodnih rakova na svetu, rod Niphargus, i dalje ima problematičnu i nerazrešenu taksonomiju. Predložene grupe dobijene na osnovu morfoloških analiza koje se danas koriste u sistematici nisu u skladu sa rezultatima molekularno filogenetskih istraživanja. Nove vrste se često otkrivaju, mahom ih odlikuje stenoendemičnost, a detektovan je i veći broj kriptičkih vrsta. Svega par vrsta nije vezano isključivo za subterestičnu slatkovodnu sredinu. Odsustvo cirkadijalnog ritma, male godišnje temperaturne oscilacije sredine koju naseljavaju i nepravilni priliv hranljivih materija je uslovio drugačije životne strategije, uključujući i razviće, u odnosu na epigejske srodnike. Sve pripadnike roda karakteriše adaptacija na hipogejsku sredinu u vidu odsustva organa vida, izduženih ekstremiteta, većeg broja taktilnih dlačica, itd. Posebnu poteškoću u određivanju taksonomije ove grupe predstavlja to što se kod nekih vrsta određene morfološke strukture, koje se mogu koristiti ili se koriste kao taksonomski karakteri, menjaju tokom ontogenije, čineći tako da juvenilni primerci jedne vrste liče na odrasle jedinke druge vrste. U cilju rasvetljavanja filogenetskih odnosa i taksonomskog statusa u okviru roda Niphargus, korišćen je integrativno taksonomski pristup i kombinacija molekularnih markera. Vršeno je i praćenje alometrijskih promena u toku ontogenije ključnih morfoloških karaktera različitih preadultnih uzrasnih kategorija. Detektovani su glavni morfološki karakteri vrsta koje su do sada registrovane na teritoriji Srbije (151 morfometrijskih i 186 merističkih). Analiza karaktera je izvršena na sakupljenim uzorcima, kao na osnovu literaturnih podataka koji su do sada objavljeni za vrste koje naseljavaju područje Srbije. Od 22 navedene vrste koje žive u Srbiji, vrsta Niphargus euserbicus je odabrana kao organizam za dalju ontogenetsku studiju. Vrsta pripada morfološkoj grupi Niphargus remyi- ravanicanus, čija ontogenija do sada nije izučavana. Odabrani su određeni morfološki karakteri koji su se pratili tokom ontogenije. Utvrđeno je koji su od stabilnih karaktera na nivou vrste podložni alometrijskom rastu. Vremensko javljanje trnova i bodlji na gnatopodama, pereopodama, epimeralnim pločama i telzonu u postembrionalnom razviću je predstavljeno sekvencom koja se može koristiti za upoređivanje među vrstama. Dobijeni podaci idu u prilog hipotezi da heterohronija igra značajnu, ako ne i ključnu ulogu, u evoluciji ovog roda. Prilikom uzorkovanja i analiza u toku ove studije, detektovana je i nova vrsta za nauku, Niphargus mirocensis u speleološkom objektu Rakin ponor, planina Miroč, zapadna Srbija. Novootkrivena vrsta je ujedno i prva vrsta roda Niphargus na području Srbije koja je dokumentovana metodama molekularne genetike. Dobijeni molekularno-filogenetski rezulati sugerišu da vrsta pripada kladi jezerske ekomorfe rasprostranjene u Italiji i centralnoj oblasti Dinarida. Vrsta ima markantnu morfologiju sa velikim i robusnim telom, dužim ekstremitetima, glomaznim i predatorskim gnatopodama, što je tipično za jezerski ekomorfe. Novo otkriće predstavlja geografsko proširenje opsega pomenute klade, čije su vrste uglavnom poznate kao stenoendemične." ]
[ "Even after countless experiments and information obtained by morphology and molecular biology, one of the most numerous genera of freshwater crustaceans in the world, Niphargus, still has a problematic and unresolved taxonomy. The proposed morphological groups, which are used today, are inconsistent with the molecular phylogeny. New species are frequently discovered and are mostly characterized by stenoendemicity, and a larger number of cryptic species have been detected. Only a few species are not related exclusively to the subterrestrial freshwater environment. The absence of circadian rhythm, smaller environmental annual temperature oscillations, and irregular inflows of nutrients have conditioned different life strategies, including their development, with regard to their epigeic relatives. The members of order are characterized by adaptation to the underground environment in the form of the absence of organs of sight, elongated extremities, a larger number of tactile hairs, etc. In some species, certain morphological structures, which can be used or are used as taxonomic characters, are changing during ontogeny, which makes juvenile specimens of these species resemble adult individuals of some other species. In order to resolve the phylogenetic relationships and taxonomical status of genus Niphargus, the combination of molecular methods and morphological analysis was used. Allometric changes during the ontogeny of key morphological characters were also observed in specimens of pre-adult age categories. Key morphological characters of the genus were detected (151 morphometric and 186 meristic). Character analysis was performed on collected samples and from literature data, for species inhabiting the territory of Serbia. During sampling a species new to science was described, Niphargus mirocensis. Of the 22 listed species, Niphargus euserbicus was chosen to be a study animal for ontogenic analysis. The species belongs to the artificial morphological group Niphargus remyi-ravanicanus, whose ontogenetic development has not been studied so far. Characters to follow during ontogenetic development were selected. They have been tested to be stable at the species level, susceptible to allometric growth and being polymorphic. The temporal occurrence of thorns and spines in postembryonic development is presented by a sequence that can be used for comparison between species. The obtained data further support the hypothesis that heterochrony plays a significant, if not a key role in the evolution of the genus. The newly discovered species Niphargus mirocensis, is the first species on the territory of Serbia that is molecularly discriminated. The obtained phylogenetic results suggest that it belongs to the clade of the lake ecomorph, also distributed in Italy and the central Dinaric region. The species has a recognizable morphology with a large and robust body, the longer body extremities, bulky and predatory gnathopods, that is typical for a lake ecomorph. The new discovery represents a geographical expansion of the range of the mentioned clade, whose species are mostly known as stenoendemic." ]
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Универзитет у Београду, Биолошки факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Београду
[ "ontogenija, filogenija, Niphargus, Srbija" ]
[ "ontogeny, phylogeny, Niphargus, Serbia" ]
[ "Ontogenija i filogenetski odnosi vrsta roda Niphargus Schiödte, 1947 (Crustacea: Amphipoda: Niphargidae) sa područja Srbije" ]
[ "Ontogeny and phylogenetic relationships of the species of the genus Niphargus Schiödte, 1947 (Crustacea: Amphipoda: Niphargus) from the territory of Srbija" ]
doctoralThesis
[ "BY-NC-ND" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/151549/Disertacija_13677.pdf", "http://nardus.mpn.gov.rs/bitstream/id/152440/Referat.pdf", "https://fedorabg.bg.ac.rs/fedora/get/o:30640/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_21543" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
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https://nardus.mpn.gov.rs/handle/123456789/10954
123456789-10954.pdf
yes
no
https://fedorakg.kg.ac.rs/fedora/get/o:1048/bdef:Content/download
no
Politički diskurs dendizma u Vajldovim komedijama društva
The Political Discourse of Dandyism in Wilde’s Society Comedies
[ "Nastić, Radmila" ]
[ "Rosić Ilić, Tatjana", "Bubanja, Nikola", "Đorić Francuski, Biljana" ]
Radovanović, Aleksandar
2019-03-25T12:54:55
[ "2019-03-25T12:54:55", "2020-07-03T15:24:14" ]
2018-11-24
[ "https://nardus.mpn.gov.rs/handle/123456789/10954", "http://eteze.kg.ac.rs/application/showtheses?thesesId=6453", "https://fedorakg.kg.ac.rs/fedora/get/o:1048/bdef:Content/download" ]
[ "Krajem XX veka, u periodu bujanja postmodernih teorija književnosti i kulture, Oskar Vajld je revitalizovan kao kanonski anglo-irski autor i rekonceptualizovan kao viktorijanska društvena ikona kroz koju se prelamaju tabuizirana seksualnost, fragmentirani nacionalni identitet i revolucionarna politička stremljenja. Prethodno marginalizovan kao šarmantni zabavljač imperijalne elite i književni diletant, Vajld je naprasno, kroz vizuru novih teorija, izrastao u mislioca čija poetika anticipira moderno, kao i postmoderno viđenje sveta i umetnosti. Ova disertacija sagledava Vajldove komedije društva kao refleksiju kulturne transformacije i političkih previranja s kraja XIX veka. Osmišljen u skladu sa konvencijama komercijalnog teatra, Vajldov komediografski izraz podrazumevao je kompromis sa dominantnim tržišnim ukusom, ali i kreativni postupak koji ima svoju subverzivnu notu. U populističkoj formi svojih komedija, Vajld je iznalazio prostor za disonantni glas koji sa izvesnom dozom suptilnosti poziva viktorijansku javnost na preispitivanje društvenih normi o aktuelnim pitanjima roda, klase, imperije i seksualnosti. Iako se u Vajldovim zapletima mogu locirati nebrojeni moderni i klasični izvori, njegova scenska delatnost pomalja se kao inventivna u realizaciji, dinamična u političkoj relevantnosti i vitalna u istorijskoj istrajnosti. Vajldova estetizovana komunikacija laganjem pokazuje se kao srodna irskoj oralnoj tradiciji, ali i filozofiji dendizma koju dramatičar vaskrsava na pozornici. Dendi je Vajldov eksponent romantičarske hirovitosti u eri viktorijanske pragmatičnosti. On je modni diktator, kulturni provokator i umetnik življenja, a odeća je njegova poezija, izraz revolta i suštinskog konformizma. 7 Dendijeva kreacija je solipsistička, ali ne odvija se u izolaciji, već kroz posmatrače. Bez svoje publike, dendi ne postoji. Postavljen na scenu, dendi kao estetsko i naizgled pasivno biće oživljava u svojstvu glasnogovornika vajldovske filozofije koja kroz ironiju i paradoks podriva društveno podobna stanovišta i formira zid jezičke ambivalentnosti koji i danas priziva nove vidove dekodiranja. Sučeljenost tradicionalnosti i inovativnosti, derivativnosti i originalnosti, konvencionalnosti i subverzije u Vajldovom dramskom postupku nagoveštava da se u samoj formi njegovih komedija može razabrati upravo ona tenzija koja sačinjava srž njegove književnosti i centralnu dihotomiju njegovog životnog i umetničkog performansa. Reč je o dendijevskoj rascepljenosti između inheretne buntovnosti i konformističke pritvornosti, na osnovu čega se Vajldove komedije prepoznaju kao medijum koji valjano odražava kompleksnost njegove poetike i obujmljuje sve kontradiktorne aspekte njegove filozofije. Ova disertacija razmatra Vajldov dramski tekst kroz pristup koji je pre društveno nego literarno orijentisan, pre materijalan nego egzistencijalan. Teza je fokusirana ne na sam tekst koliko na socijalnu interaktivnost teksta u političkim, istorijskim i kulturološkim diskursima Britanske imperije na izmaku viktorijanske epohe. Vajldove komedije otuda su sagledane kao dramska književnost i pozorišni performans, ali i kao kulturni artefakt i scensko ogledalo poznoviktorijanskog sveta u tranziciji. U svom istraživanju, teza se oslanja na masivan kritički korpus o Vajldu, ali i teži da se nadoveže na njega, predoči sopstvenu argumentaciju i izvrši blago pomeranje diskusije ka manje ispitanim obodima. Podrobnije upoznavanje sa politikom Vajldove komedije i njene publike proširiće i humanizovati naš fiksirani pogled na viktorijance i pružiti mu dodatnu istorijsku dimenziju. U tom procesu, disertacija će predočiti načine na koje Vajldova poetika reflektuje kulturne osobenosti fin de siècle Britanije, ali i podstiče zapitanost nad ljudskim stanjem u maniru koji je podjednako prijemčiv za našu digitalnu epohu." ]
[ "Towards the end of the twentieth century, Oscar Wilde was revitalized as a canonical Anglo-Irish author and re-conceptualized as a Victorian social icon who embodied tabooed sexuality, fragmented national identity and revolutionary political aspirations. Previously marginalized as a charming entertainer of the imperial elite and a literary dilettante, Wilde sprang into academic recognition as a thinker whose poetics anticipated the modern, as well as postmodern conception of the world and art. This dissertation examines Wilde’s society comedies as a reflection of cultural transformation and political turmoil at the close of the nineteenth century. Conceived in accord with the conventions of commercial theatre, Wilde’s dramatic expression was marked by a compromise with the dominant taste of the market, but it also entailed a creative strategy which had its subversive note. In the populist form of his comedy, Wilde found space for a subtle dissonant voice which invited the Victorian audiences to review social norms on the topical issues of gender, class, empire and sexuality. Although Wilde’s plots reveal countless modern and classical sources, his plays loom as inventive in execution, dynamic in political relevance and vital in historical durability. Wilde’s aestheticized communication through lying proves to be akin to the Irish oral tradition as well as the philosophy of dandyism which the playwright revived on the stage. The dandy is Wilde’s exponent of romantic whimsicality in the era of Victorian pragmatism. He is a fashion dictator, cultural provocateur and a supreme artist of life. Clothing is his poetry, a sartorial expression of his apparent revolt and essential conformity. The dandy’s creation is solipsistic, but it does not enfold in isolation. Without his audience, the dandy does not exist. Once he is placed on the stage, the dandy, as an aesthetic and seemingly passive creature, comes to life as the spokesman of Wildean philosophy which uses irony 9 and paradox to undermine socially acceptable views and to build a wall of linguistic ambivalence which still invokes new forms of decoding. Wilde’s dramatic method thrives on the oppositions between traditionalism and innovation, derivativeness and originality, conventionality and subversion, thus suggesting that the very form of his comedy exemplifies the tension which stands as the existential core of his literature and the central dichotomy of his performance of life. That tension is the dandy’s schism between inherent rebellion and conformist pretence, which is why Wilde’s comedies can be recognized as a medium that properly reflects the complexity of his poetics and embraces all the contradictory aspects of his philosophy. The approach to Wilde’s dramatic text is socially rather than literarily inclined, material rather than existential. The dissertation is focused not on the text itself but on the social interactivity of the text within the political, historical and cultural discourses of the British Empire at the apex of its power. Wilde’s comedy is therefore observed as dramatic literature and theatrical performance, but also as a cultural artefact and a stage mirror of the late Victorian world in transition. The research relies on the massive body of critical work on Wilde, but it also aims to complement it, present its own argument and make a slight shift of the discussion towards the less examined edges. A keener awareness of the politics of Wilde’s comedy and its audience serves to expand and humanize our fixed view of the Victorians and provide it with an additional historical dimension. In this process, the dissertation will demonstrate the ways in which Wilde’s poetics not only reflects the cultural traits of the fin de siècle Britain, but also evokes a sense of wonder about the human condition in a fashion which is just as provocative in our digital era." ]
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Универзитет у Крагујевцу, Филолошко-уметнички факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Крагујевцу
[ "Oskar Vajld", "poznoviktorijanska kultura", "dendizam", "dekadencija", "viktorijansko pozorište" ]
[ "Oscar Wilde", "late Victorian culture", "dandyism", "decadence", "Victorian theatre" ]
[ "Politički diskurs dendizma u Vajldovim komedijama društva" ]
[ "The Political Discourse of Dandyism in Wilde’s Society Comedies" ]
doctoralThesis
[ "BY-NC-ND" ]
[ "https://nardus.mpn.gov.rs/bitstream/id/50977/Disertacija.pdf", "https://nardus.mpn.gov.rs/bitstream/id/50978/Aleksandar_Radovanovic_FILUM.pdf", "http://nardus.mpn.gov.rs/bitstream/id/50977/Disertacija.pdf", "http://nardus.mpn.gov.rs/bitstream/id/50978/Aleksandar_Radovanovic_FILUM.pdf", "https://fedorakg.kg.ac.rs/fedora/get/o:1048/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_10954" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
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[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/7475
123456789-7475.pdf
yes
no
https://fedorani.ni.ac.rs/fedora/get/o:1251/bdef:Content/download
no
Novi pristup u proceni pravca dolazećeg EM signala zasnovan na primeni veštačkih neuronskih mreža
[ "Milovanović, Branislav" ]
[ "Dončov, Nebojša", "Marković, Vera", "Jokanović, Branka", "Maleš-Ilić, Nataša" ]
Stoilković, Marija M.
2017-02-08T10:31:40
[ "2017-02-08T10:31:40", "2020-07-03T16:02:11" ]
2015-06-26
[ "https://nardus.mpn.gov.rs/handle/123456789/7475", "http://eteze.ni.ac.rs/application/showtheses?thesesId=4547", "https://fedorani.ni.ac.rs/fedora/get/o:1251/bdef:Content/download", "http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70052&RID=533868182" ]
[ "" ]
[ "Direction of Arrival (DOA) estimation of electromagnetic (EM) signals strongly depends on characteristics of received signals, configuration and physical layout of a receiving antenna array and environmental conditions. DOA algorithms have crucial role in adaptive antenna systems where used to provide better reception of desired signals and to suppress interference. Consequently, they have significant impact on system capacity. So far, numerous DOA algorithms have been developed assuming different configurations of antenna arrays and characteristics of EM signals. The main problem that appears when these algorithms are applied in practice is that a compromise between accuracy of the results and speed of calculation must be made. For that reason, a method for DOA estimation based on Artificial Neural Networks (ANNs) is applied in this dissertation. The main contribution of this work is development of neural models for the efficient and accurate DOA estimation of EM signals both in azimuth and elevation. Assuming rectangular antenna array geometry at the receiver, neural models for 2D DOA estimation of uncorrelated and coherent signals are developed. It is shown that applying a hierarchical neural model can greatly affect the accuracy of DOA estimates when compared to standard superresolution algorithms. To develop neural models, the observed space is divided into sectors in azimuth and elevation. The neural networks in the first stage of the model are trained to detect presence of electromagnetic sources, while the networks in the second stage are trained to provide precise DOA estimates. The appropriately trained hierarchical model, composed of smaller neural networks, can be used for accurate DOA estimation in azimuth and elevation. As follows, time to train separate networks is drastically reduced as different training sets are used for the networks in the detection and estimation stage. The proposed models are very efficient, able to provide DOA estimates in a matter of seconds and very suitable for real time application. Performances of the models are experimentally verified. Besides, the results are compared with the results of the standard algorithm for DOA estimation. Advantages of the proposed models are accuracy of DOA estimates and speed of calculation. In addition, neural models can be trained to account for some other characteristics of EM signals (number of signals, signal to noise ratio, correlation between signals), physical characteristics of the receiving array and environmental conditions. Influence of signal to noise ratio (SNR) on the performance of neural models, aimed for DOA estimation of signals in azimuth plane, is also investigated. It is shown that SNR strongly affects the accuracy of DOA estimates, and as such should be involved as an additional parameter in the process of training of a neural network. Further, detection of correlated signals is investigated assuming circular antenna array geometry. In this case, neural models are developed for different number of signals and correlation between them. In this dissertation, application of artificial neural networks in DOA estimation of radar MIMO (Multiple Input Multiple Output) – OFDM (Orthogonal Frequency Division Multiplexing) signals is presented. A neural model is optimized and its performance is compared to conventional algorithm regarding accuracy and time consumption." ]
application/pdf
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Универзитет у Нишу, Електронски факултет
[ "info:eu-repo/grantAgreement/MESTD/Technological Development (TD or TR)/32052/RS//" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc/4.0/" ]
Универзитет у Нишу
[ "antenski nizovi", "MUSIC algoritam", "procena pravca EM signala", "prostorna kovarijansna matrica", "prostorna obrada signala", "veštačke neuronske mreže" ]
[ "antenna arrays", "artificial neural networks", "DOA estimation", "MUSIC algorithm", "spatial covariance matrix", "spatial signal processing" ]
[ "Novi pristup u proceni pravca dolazećeg EM signala zasnovan na primeni veštačkih neuronskih mreža" ]
[ "" ]
doctoralThesis
[ "BY-NC" ]
Миловановић, Бранислав; Дончов, Небојша; Марковић, Вера; Јокановић, Бранка; Малеш-Илић, Наташа; Стоилковић, Марија М.; Нови приступ у процени правца долазећег ЕМ сигнала заснован на примени вештачких неуронских мрежа; Нови приступ у процени правца долазећег ЕМ сигнала заснован на примени вештачких неуронских мрежа;
[ "https://nardus.mpn.gov.rs/bitstream/id/52175/Disertacija7496.pdf", "http://nardus.mpn.gov.rs/bitstream/id/52175/Disertacija7496.pdf", "https://fedorani.ni.ac.rs/fedora/get/o:1251/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_7475" ]
[ "" ]
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https://nardus.mpn.gov.rs/handle/123456789/21562
123456789-21562.pdf
yes
no
https://fedorabg.bg.ac.rs/fedora/get/o:30525/bdef:Content/download
no
Уопштења Шатенових норми графова и комбинаторне примене
Extended Schatten norms of graphs and combinatorial applications
[ "Božin, Vladimir" ]
[ "Mateljević, Miodrag", "Jocić, Danko", "Stanić, Zoran", "Erić, Aleksandra" ]
Lazarević, Ivan
2023-09-06T11:00:27
[ "2023-09-06T11:00:27" ]
2022-07-12
[ "https://uvidok.rcub.bg.ac.rs/bitstream/handle/123456789/4784/Referat.pdf", "https://eteze.bg.ac.rs/application/showtheses?thesesId=9188", "https://fedorabg.bg.ac.rs/fedora/get/o:30525/bdef:Content/download", "https://plus.cobiss.net/cobiss/sr/sr/bib/121605129", "https://nardus.mpn.gov.rs/handle/123456789/21562" ]
[ "У овој докторској дисертацији добијени су неки резултети у области теорије графова и њених примена." ]
[ "In this doctoral thesis we obtained some results in graph theory and its applica- tions. In the rst chapter, we give the review of basic notions and theorems of combinatorial theory of graphs, spectral theory of graphs, random graphs and distribution of their eigenvalues. The most detailed consideration is given to adjacency matrix and properties of its spectrum. In particular, in this dissertation we study Energy of graphs and generalizations of it. Energy of graph is the sum of absolute values of eigenvalues of a graph. Schatten norms of graphs represent p-th degree norm of singular values of graph, and the special cases of this norm for p = 1 corresponds to the Energy of graph. In chapter three of this dissertation we are given the most original scientic contribution. We prove the conjecture of Nikiforov about Schatten norms of graphs when p > 2. First we prove that conjecture is true for some special classes of graph (for trees and strongly regular graph with maximal energy). After that, we prove the conjecture in the general case. Auxiliary theorem obtained in the proof of this conjecture is also an original result which gives a sharp upper bound of sum of quadratic of the largest k singular values of graph. A corollary of this theorem which gives an upper bound for sum of squares of the biggest two singular values of graph can be useful in further research. In the subsection 3.3 we give an original theorem about asymptotic properties of spectrum and thus energy of complement graph for a large values of n. In the subsection 3.4 we calculate a mean of p-th degree of singular values and upper bound of geometric mean of almost all graphs. The last chapter shows relation between combinatorial theory of graphs with universal universal algebra and mathematical logic. The central part of this chapter is original and shorter proof of an important theorem which solves a dichotomy conjecture for CSP problem on undirected graphs." ]
application/pdf
sr
Универзитет у Београду, Математички факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Београду
[ "" ]
[ "" ]
[ "Уопштења Шатенових норми графова и комбинаторне примене" ]
[ "Extended Schatten norms of graphs and combinatorial applications" ]
doctoralThesis
[ "BY-NC-ND" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/151604/Disertacija_13649.pdf", "http://nardus.mpn.gov.rs/bitstream/id/152493/Referat.pdf", "https://fedorabg.bg.ac.rs/fedora/get/o:30525/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_21562" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/18882
123456789-18882.pdf
yes
no
https://fedorabg.bg.ac.rs/fedora/get/o:24854/bdef:Content/download
no
Istraživanje faktora koji određuju pružanje preventivnih usluga u primarnoj zdravstvenoj zaštiti
Investigation of factors determining the provision of preventive services in primary health care
[ "Janković, Janko V." ]
[ "Maksimović, Nataša", "Bjegović Mikanović, Vesna", "Kisić-Tepavčević, Darija", "Ukropina, Snežana" ]
Mitričević, Slavka
2022-01-17T12:20:32
[ "2022-01-17T12:20:32" ]
2021-10-07
[ "http://eteze.bg.ac.rs/application/showtheses?thesesId=8466", "https://fedorabg.bg.ac.rs/fedora/get/o:24854/bdef:Content/download", "http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=53152265", "https://nardus.mpn.gov.rs/handle/123456789/18882" ]
[ "Korišćenje preventivnih zdravstvenih usluga prepoznato je kao dugoročno zdravstveno ulaganje zbog svog potencijala da pomogne pojedincima da brinu o svom zdravlju. Ova studija imala je za cilj da istraži dostupnost i pružanje preventivnih zdravstvenih usluga u primarnoj zdravstvenoj zaštiti (PZZ) u oblastima rada opšte medicine, pedijatrije i ginekologije, kao i da analizira uticaj sociodemografskih i zdravstvenih faktora na pružanje preventivnih zdravstvenih usluga. Metod: Ova studija preseka koristila je podatake Republičkog fonda za zdravstveno osiguranje i Republičkog zavoda za statistiku Srbije za 2015. i 2018. godinu. U analizu je uključeno 149 opština sa nezavisnim jedinicama PZZ. Za ispitivanje povezanosti između pružanja preventivnih usluga i sociodemografskih i zdravstvenih karakteristika stanovništva korišćene su bivarijantne i multivarijantne regresione analize. Rezultati: U modelu višestruke regresije za domen pedijatrije, veći broj pruženih preventivnih zdravstvenih usluga na 1.000 dece, imale su opštine gde su deca imala višu stopu završetka osnovne škole (p=0.024) u 2015 i (p=0.023) 2018. god. Veći izdaci za zdravstvenu zaštitu (p=0.017) u 2015. god, veće očekivano trajanje života na rođenju (p=0.041) u 2015. god. i deca iz urbanih sredina u 2018. god. (p=0.020) takođe su promenljive koje su bile pozitivno povezane sa brojem pruženih preventivnih zdravstvenih usluga kod izabranog lekara. Što se tiče oblasti opšte medicine, višestruka regresiona analiza pokazala je da odraslo stanovništvo (19+) sa većim izdvajanjima za zdravstvenu zaštitu po glavi stanovnika (p=0.006) u 2015. god. i većom stopom završetka osnovne škole (p=0.004) u 2018. god., kao i većom prosečnom zaradom (USD) (p=0.018) u 2018. god. u većoj meri koristi preventivne usluge na 1.000 odraslih. Što je bila veća smrtnost od hroničnih nezaraznih bolesti (p=0.003) u 2015.god. i (p=0.012) u 2018. god. to je više preventivnih usluga pružio izabrani lekar opšte medicine. U ginekološkoj oblasti jedina promenljiva koja je bila značajno povezana sa brojem preventivnih zdravstvenih usluga na 1.000 žena u višestrukoj linearnoj regresiji bila je stopa plodnosti (p=0.003) u 2015. god. Ženska populacija (15+) sa većom stopom završetka osnovne škole (p=0.011) i koja živi u urbanim sredinama (p=0.046) u 2018. god. više je koristila preventivne usluge kod izabranog ginekologa u PZZ. Promenljive koje su pokazale pozitivnu korelaciju (r) sa upotrebom preventivnih usluga i značajnu razliku (p<0.001) između dva ispitivana perioda (2015-2018. god.) su: demografske - urbana populacija (r=0.995), udeo populacije 65+ godina (r=0.993); socioekonomske - stopa nezaposlenosti (r=0.951), proseča zarada zaposlenih (r= 0.826), rashodi za zdravstvenu zaštitu (r=0.812) i zdravstvene karakteristike populacije - ukupni mortalitet od HNB (r=0.899) i mortalitet od kardiovaskularnih bolesti (r=0.894). Od indikatora dostupnosti izabranih lekara i performansi usluga u PZZ, pozitivnu korelaciju (r) sa brojem ostvarenih preventivnih usluga (2015-2018. god.) pokazali su, u opštoj medicini: broj lekara (p<0.001; r=0.949), broj lekara na 10.000 ciljne populacije (p<0.001); r=0.789) i ukupan broj poseta po izabranom lekaru (p<0.009; r=595), dok su u pedijatriji: broj lekara (p<0.044; r=0.944) i u ginekologiji: broj lekara na 10.000 ciljne populacije (p<0.028; r=0.698). Zaključak: Ova studija identifikovala je faktore koji utiču na pružanje preventivnih zdravstvenih usluga u PZZ. Najvažniji prediktori korišćenja preventivnih zdravstvenih usluga su stopa završetka osnovne škole, procenat urbane populacije, prosečna zarada zaposlenih (USD), ukupna stopa smrtnosti od HNB i broj izabranih lekara u PZZ." ]
[ "The use of preventive health services has been recognized as a long-term health investment because of its potential to help individuals take care of their health. This study aimed to investigate the availability and provision of preventive health services in primary health care (PHC) in the fields of general medicine, pediatrics and gynecology, as well as to analyze the impact of sociodemographic and health factors on the provision of preventive health services. Method: This cross-sectional study used data from the Republic Health Insurance Fund and the Republic Bureau of Statistics of Serbia for 2015 and 2018. The analysis included 149 municipalities with independent PHC units. Bivariate and multivariate regression analyzes were used to examine the relationship between the provision of preventive services and the sociodemographic and health characteristics of the population. Results: In the multiple regression model for the domain of pediatrics, a larger number of provided preventive health services per 1,000 children were in municipalities where children had a higher primary school completion rate (p = 0.024) in 2015 and (p = 0.023) 2018. Higher health care expenditures (p = 0.017) in 2015, higher life expectancy at birth (p = 0.041) in 2015. and children from urban areas in 2018. (p = 0.020) are also variables that were positively related to the number of preventive health services provided by the chosen physician. Regarding the field of general medicine, multiple regression analysis showed that the adult population (19+) with higher spending for health care per capita (p = 0.006) in 2015. and a higher primary school completion rate (p = 0.004) in 2018. And higher average earnings (USD) (p = 0.018) in 2018. it used more preventive services per 1,000 adults. The higher the mortality from chronic non-communicable diseases (p = 0.003) in 2015. and (p = 0.012) in 2018. that is, more preventive services were provided by a chosen general practitioner. In the gynecological field, the only variable that was significantly related to the number of preventive health services per 1,000 women in multiple linear regression was the fertility rate (p = 0.003) in 2015. Female population (15+) with a higher completion rate of primary school (p = 0.011) and living in urban areas (p = 0.046) in 2018. used preventive services a chosen gynecologist in PHC. Variables that showed a positive correlation (r) with the use of preventive services and a significant difference (p <0.001) between the two examined periods (2015-2018) are: demographic - urban population (r = 0.995), share of population 65+ years (r = 0.993); socio-economic - unemployment rate (r = 0.951), average salary of employees (r = 0.826), health care expenditures (r = 0.812) and health characteristics of the population - total mortality from the CND (r = 0.899) and mortality from cardiovascular diseases (r = 0.894). Regarding indicators of availability of selected doctors and performance of services in PHC, a positive correlation (r) with the number of realized preventive services (2015-2018) was noted, in general medicine: number of doctors (p <0.001; r = 0.949), number of doctors per 10,000 target population (p <0.001); r = 0.789) and the total number of visits per selected physician (p <0.009; r = 595), while in pediatrics: number of physicians (p <0.044; r = 0.944) and in gynecology: number of physicians per 10,000 target populations (p <0.028 ; r = 0.698). Conclusion: This study identified factors influencing the provision of preventive health services in PHC. The most important predictors of the use of preventive health services are the primary school completion rate, the percentage of the urban population, the average salary of employees (USD), the total mortality rate from the CND and the number of selected doctors in PHC." ]
application/pdf
sr
Универзитет у Београду, Медицински факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Београду
[ "faktori", "preventivne zdravstvene usluge", "primarna zdravstvena zaštita", "pružanje usluga" ]
[ "factors", "preventive health services", "primary health care", "provision of services" ]
[ "Istraživanje faktora koji određuju pružanje preventivnih usluga u primarnoj zdravstvenoj zaštiti" ]
[ "Investigation of factors determining the provision of preventive services in primary health care" ]
doctoralThesis
[ "BY-NC-ND" ]
Јанковић, Јанко В.; Максимовић, Наташа; Бјеговић Микановић, Весна; Кисић-Тепавчевић, Дарија; Укропина, Снежана; Митричевић, Славка; Истраживање фактора који одређују пружање превентивних услуга у примарној здравственој заштити; Истраживање фактора који одређују пружање превентивних услуга у примарној здравственој заштити;
[ "http://nardus.mpn.gov.rs/bitstream/id/141849/Disertacija_12011.pdf", "http://nardus.mpn.gov.rs/bitstream/id/141850/Izvestaj_Komisije_12011.pdf", "https://fedorabg.bg.ac.rs/fedora/get/o:24854/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_18882" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/18909
123456789-18909.pdf
yes
no
https://fedorabg.bg.ac.rs/fedora/get/o:24875/bdef:Content/download
no
Razvoj i in vitro/in silico karakterizacija lipidnih formulacija sa simvastatinom kao model supstancom
Formulation and in vitro/in silico characterization of lipid-based drug delivery systems with simvastatin as model substance
[ "Vasiljević, Dragana" ]
[ "Cvijić, Sandra", "Ibrić, Svetlana", "Radojević, Vesna" ]
Ćetković, Zora
2022-01-21T15:33:12
[ "2022-01-21T15:33:12" ]
2021-09-27
[ "http://eteze.bg.ac.rs/application/showtheses?thesesId=8476", "https://fedorabg.bg.ac.rs/fedora/get/o:24875/bdef:Content/download", "http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=49206793", "https://nardus.mpn.gov.rs/handle/123456789/18909" ]
[ "nisku rastvorljivost u vodi/gastrointestinalnim (GI) tečnostima, koja je ograničavajući faktor za apsorpciju, a samim tim i biološku raspoloživost lekovite supstance. Jedan od pristupa za prevazilaženje ovog problema je izrada lipidnih formulacija, u koje spadaju i samomikroemulgujući sistemi (SMEDDS). Simvastatin je lekovita supstanca iz grupe statina, koja se koristi za snižavanje koncentracije holesterola u krvi, poseduje i vaskuloprotektivna svojstva, a najnovija istraživanja pokazuju i da ispoljava određenu efikasnost u lečenju tumora dojke, kolona i prostate. Zbog niske biološke raspoloživosti simvastatina nakon peroralne primene tableta sa trenutnim oslobađanjem, jedinog farmaceutskog oblika sa simvastatinom na tržištu, sve je veća potreba za razvojem savremenih nosača koji bi omogućili veću biološku raspoloživost ove lekovite supstance. Stoga, sveobuhvatni cilj ove doktorske disertacije je bio razvoj novih lipidnih formulacija sa aspekta potencijalne primene kao nosača nove generacije za peroralnu primenu simvastatina i njihova fizičkohemijska i biofarmaceutska karakterizacija. U prvoj fazi istraživanja formulisani su tečni SMEDDS, kao potencijalni nosači za peroralnu primenu simvastatina, koji omogućavaju povećanje rastvorljivosti i brzine rastvaranja ove lekovite supstance. Od ukupno 54 različite kombinacije ulja (oleoil makrogol-6 gliceridi, propilenglikol monokaprilat, propilenglikol monolaurat), surfaktanta (kaprilokaproil makrogol-8 gliceridi) i kosurfaktanta (polisorbat 80 ili makrogol 15 hidroksistearat), odabrani su uzorci koji su odgovarali kriterijumima za SMEDDS u pogledu brzine samoemulgovanja (< 1 min), robusnosti prema razblaživanju (transparencija ˃ 99%), veličine kapi (< 100 nm) i raspodele veličine kapi (PDI < 0,2), kao i prihvatljive stabilnosti tokom šestomesečnog skladištenja na sobnoj temperaturi (22 ± 2 °C). Simvastatin se iz odabranih tečnih SMEDDS oslobađao brzo, čime je potvrđeno da se formulisanjem tečnih SMEDDS značajno povećava brzina rastvaranja simvastatina. U drugoj fazi istraživanja, primenom kompjuterskog programa GastroPlus™, uspešno je razvijen simvastatin-specifični fiziološki zasnovan farmakokinetički (PBPK) model, koji na odgovarajući način opisuje apsorpciju, konverziju u simvastatin-kiselinu, raspodelu i eliminaciju simvastatina. Analizom literaturnih podataka, eksperimentalnih podataka i in silico predviđenih vrednosti parametara koji opisuju biofarmaceutska svojstva simvastatina i fiziološke karakteristike organizma, odabran je set ulaznih parametara koji su korišćeni za in silico modelovanje. Izgrađeni PBPK model je validiran poređenjem predviđenih sa in vivo vrednostima farmakokinetičkih parametara za simvastatin i simvastatin-kiselinu nakon peroralne primene 20 mg simvastatina u obliku tableta sa trenutnim oslobađanjem. Rezutati in vitro ispitivanja tečnih SMEDDS, punjenih u tvrde kapsule su pokazali da ove formulacije omogućavaju povećanje brzine rastvaranja simvastatina. Međutim, in silico modelovanjem je pokazano da se na ovaj način ne povećava biološka raspoloživosti simvastatina, u poređenju sa tabletama simvastatina sa trenutnim oslobađanjem. Analizom rezultata simulacija je utvrđeno da su distalni delovi GI trakta optimalno mesto za apsorpciju simvastatina, te se razvojem formulacija sa modifikovanim (ciljnim) oslobađanjem simvastatina može postići smanjenje uticaja presistemskog metabolizma i povećanje biološke raspoloživosti ove lekovite supstance. U trećoj fazi istraživanja formulisane su lipidne formulacije sa modifikovanim oslobađanjem simvastatina, punjenjem odabranih tečnih SMEDDS u acidorezistentne kapsule, kao i mešanjem odabranih tečnih SMEDDS sa kopolimerima metakrilne kiseline, koji pokazuju pH zavisnu rastvorljivost. Korišćeni su polimeri Eudragit® L100, Eudragit® S100, kao i njihova kombinacija, u odnosu 1:1, a odnos SMEDDS:polimer je bio 2:1. Rezultati in vitro ispitivanja brzine rastvaranja simvastatina pod uslovima izmene medijuma su pokazali da je punjenje tečnih SMEDDS u acidorezistentne kapsule omogućilo oslobađanje simvastatina nakon 90 min, u medijumu pH 6,4. Poređenjem rezultata in vitro ispitivanja brzine rastvaranja simvastatina iz formulacija, dobijenih mešanjem tečnih SMEDDS sa Eudragit® polimerima punjenih u tvrde kapsule, zaključeno je da postoji jasna zavisnost između brzine rastvaranja/oslobađanja simvastatina i vrste Eudragit® polimera..." ]
[ "ABSTRACT More than 50% of the marketed drugs and approximately 90% of new drug entities are poorly soluble in water/gastrointestinal (GI) fluids, which is a limiting factor for their absorption and bioavailability. One of the approaches to overcome this issue is based on the design of lipid-based drug delivery systems, including self-microemulsifying drug delivery systems (SMEDDS). Simvastatin belongs to statins, the class of drugs used to lower cholesterol levels in the blood; it also has vasculoprotective properties, and recent research shows that simvastatin exhibits certain activity in the treatment of breast, colon and prostate cancer. Due to low bioavailability of this drug following oral administration of immediate-release tablets, the only dosage form of simvastatin available on the market, there is a growing need for the development of modern carriers that would improve its oral bioavailability. Therefore, the overall aim of this doctoral dissertation was to develop novel lipid-based drug delivery systems as carriers for oral administration of simvastatin, along with their physicochemical and biopharmaceutical characterization. In the first phase of the study, liquid SMEDDS were formulated, as potential carriers for oral administration of simvastatin, which improved the drug solubility and dissolution rate. Out of 54 different combinations of oils (oleoyl macrogol-6 glycerides, propylene glycol monocaprylate, propylene glycol monolaurate), surfactant (caprylocaproyl macrogol-8 glycerides) and cosurfactant (polysorbate 80 or macrogol 15 hydroxystearate), only formulations with acceptable selfemulsification rate (< 1 min), robustness to dilution (transparency ˃ 99%), droplet size (< 100 nm) and polydispersity index (PDI < 0.2), which proved to be stable during six-month storage at room temperature (22 ± 2 °C) were selected. Simvastatin was rapidly released from the selected liquid SMEDDS, confirming that liquid SMEDDS significantly improved the dissolution rate of simvastatin. In the second phase of the study, using the GastroPlus™ software, a drug-specific physiologically-based pharmacokinetic (PBPK) model was successfully developed, which appropriately describes the absorption, conversion to simvastatin-acid, distribution and elimination of simvastatin. After analyzing literature and experimental data, together with in silico predicted values to describe simvastatin biopharmaceutical properties and physiological characteristics of the human body, a set of input parameters used for in silico modeling was selected. The constructed PBPK model was validated by comparing the estimated values with the in vivo data on pharmacokinetic parameters for simvastatin and simvastatin-acid following oral administration of 20 mg simvastatin immediate-release tablets. In vitro drug dissolution profiles from liquid SMEDDS, filled into hard gelatin capsules, showed that these formulations improved the dissolution rate of simvastatin. However, in silico results demonstrated that this strategy would not lead to the enhancement of drug oral bioavailability compared to immediate-release tablets. In addition, simulation results showed that distal parts of the GI tract are the optimal place for simvastatin absorption, and that formulation of modified (targeted)-release oral dosage forms of simvastatin could reduce the effects of presystemic metabolism and improve oral bioavailability of this drug. In the third phase of the study, modified-release lipid-based drug delivery systems were formulated by filling the selected liquid SMEDDS into acid-resistant capsules, as well as by mixing the selected liquid SMEDDS with pH-dependent methacrylic acid copolymers. Eudragit® L100 and Eudragit® S100 polymers, as well as their combination (in the ratio 1:1) were used, whereas the ratio SMEDDS:polymer was 2:1. In vitro dissolution results under medium-change conditions showed that liquid SMEDDS filled into acid-resistant capsules enabled complete drug release after 90 min in medium pH 6.4. Comparison of the in vitro dissolution test results for formulations obtained by mixing liquid SMEDDS with Eudragit® polymers filled into hard gelatin capsules, pointed out that there was a clear relationship between simvastatin release rate and the type of Eudragit® polymer. Simvastatin was completely released from all formulations with Eudragit® L100 after 180 min in medium pH 6.9. The presence of Eudragit® S100 in the formulations enabled complete simvastatin release after 300 min in medium pH 7.4. .." ]
application/pdf
sr
Универзитет у Београду, Фармацеутски факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Београду
[ "samomikroemulgujući sistemi (SMEDDS)", "simvastatin", "kopolimeri metakrilne kiseline", "lipidne formulacije sa modifikovanim oslobađanjem", "rastvorljivost", "pH zavisna brzina rastvaranja", "fiziološki zasnovano farmakokinetičko (PBPK) modelovanje" ]
[ "self-microemulsifying drug delivery systems (SMEDDS)", "simvastatin", "polymethacrylate polymers", "modified-release lipid-based formulations", "solubility", "pH-controlled drug release", "physiologically-based pharmacokinetic (PBPK) modeling" ]
[ "Razvoj i in vitro/in silico karakterizacija lipidnih formulacija sa simvastatinom kao model supstancom" ]
[ "Formulation and in vitro/in silico characterization of lipid-based drug delivery systems with simvastatin as model substance" ]
doctoralThesis
[ "BY-NC-ND" ]
Васиљевић, Драгана; Ибрић, Светлана; Цвијић, Сандра; Радојевић, Весна; Ћетковић, Зора; Развој и ин витро/ин силицо карактеризација липидних формулација са симвастатином као модел супстанцом; Развој и ин витро/ин силицо карактеризација липидних формулација са симвастатином као модел супстанцом;
[ "http://nardus.mpn.gov.rs/bitstream/id/142006/Disertacija_12049.pdf", "http://nardus.mpn.gov.rs/bitstream/id/142007/Izvestaj_Komisije_12049.pdf", "https://fedorabg.bg.ac.rs/fedora/get/o:24875/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_18909" ]
[ "" ]
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https://nardus.mpn.gov.rs/handle/123456789/18910
123456789-18910.pdf
yes
no
https://fedorabg.bg.ac.rs/fedora/get/o:24878/bdef:Content/download
no
Hemometrijski podržana karakterizacija hromatografskih sistema modifikovanih beta-ciklodekstrinom sa model supstancama
Chemometrically assisted characterization of betha-cyclodextrin modified chromatographic systems with selected model substances
[ "Protić, Ana" ]
[ "Otašević, Biljana", "Zečević, Mira", "Golubović, Jelena" ]
Đajić, Nevena
2022-01-21T15:33:14
[ "2022-01-21T15:33:14" ]
2021-09-24
[ "http://eteze.bg.ac.rs/application/showtheses?thesesId=8477", "https://fedorabg.bg.ac.rs/fedora/get/o:24878/bdef:Content/download", "http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=49073417", "https://nardus.mpn.gov.rs/handle/123456789/18910" ]
[ "Ciklodekstrini (eng. Cyclodextrins – CDs) su poznati po svojoj sposobnosti da grade inkluzione komplekse sa različitim molekulima. Ova osobina je odgovorna za njihovu primenu kao aditiva mobilne faze u razvoju ekološki prihvatljivih metoda reverzno-fazne tečne hromatografije pod visokim pritiskom (eng. Reversed-Phase High-Performance Liquid Chromatography – RP-HPLC). Sprovedena je karakterizacija inkluzionih kompleksa koji se formiraju između β-CD-a i odabrane model smeše, koju čine risperidon, olanzapin i njihove srodne supstance. Stehiometrija kompleksa 1:1 je potvrđena masenom spektrometrijom sa elektrosprej jonizacijom. Molekulskom doking studijom predviđene su termodinamički najstabilnije strukture inkluzionih kompleksa, koje su potvrđene nuklearnom magnetno-rezonantnom spektroskopijom. Uspostavljen je kvantitativni odnos strukture i retencije (eng. Quantitative Structure-Retention Relationship – QSRR) uključivanjem deskriptora koji opisuju inkluzione komplekse, molekulskih deskriptora i eksperimentalnih parametara. QSRR model razvijen uz pomoć veštačkih neuronskih mreža (eng. Artificial Neural Network – ANN) je primenjen u razvoju ekološki prihvatljivih RP-HPLC metoda. i izračunavanju konstanti stabilnosti i termodinamičkih parametara kompleksiranja. Otkriveno je da HPLC metoda nije univerzalno primenljiva u izračunavanju navedenih parametara. U sistemu gde β-CD nije prisutan u mobilnoj fazi, uočeno je razdvajanje pika srodne supstance B od pika inkluzionog kompleksa, a detekcija je sprovedena detektorom naelektrisanja u aerosolu. Kod supstanci gde nije došlo do navedenog razdvajanja, predložen je novi metodološki pristup izračunavanju konstanti stabilnosti. Razvijen je i QSRR-ANN model sa opsežnim setom molekulskih deskriptora, koji je omogućio identifikaciju strukturnih karakteristika od značaja za formiranje inkluzionih kompleksa i retenciono ponašanje model supstanci. Utvrđeno je da retenciono ponašanje u velikoj meri zavisi od molekulskih dimenzija i oblika, lipofilnosti i udaljenosti od geometrijskog centra grupa koje ostvaruju interakcije sa β-CD-om." ]
[ "" ]
application/pdf
sr
Универзитет у Београду, Фармацеутски факултет
[ "info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172033/RS//" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Београду
[ "Ciklodekstrin", "Inkluzioni kompleks", "RP-HPLC", "Konstanta stabilnosti", "QSRR", "ANN", "Ekološki prihvatljiva metoda", "Molekulski deskriptor", "Molekulska doking studija", "Deskriptori inkluzionih kompleksa" ]
[ "Cyclodextrin", "Inclusion complex", "RP-HPLC", "Stability constant", "QSRR", "ANN", "Ecologically acceptable method", "Molecular descriptor", "Molecular docking study", "Descriptors describing inclusion complexes" ]
[ "Hemometrijski podržana karakterizacija hromatografskih sistema modifikovanih beta-ciklodekstrinom sa model supstancama" ]
[ "Chemometrically assisted characterization of betha-cyclodextrin modified chromatographic systems with selected model substances" ]
doctoralThesis
[ "BY-NC-ND" ]
Протић, Aна; Голубовић, Јелена; Зечевић, Мира; Оташевић, Биљана; Ђајић, Невена; Хемометријски подржана карактеризација хроматографских система модификованих бета-циклодекстрином са модел супстанцама; Хемометријски подржана карактеризација хроматографских система модификованих бета-циклодекстрином са модел супстанцама;
[ "http://nardus.mpn.gov.rs/bitstream/id/142010/Disertacija_12050.pdf", "http://nardus.mpn.gov.rs/bitstream/id/142009/Referat.pdf", "https://fedorabg.bg.ac.rs/fedora/get/o:24878/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_18910" ]
[ "" ]
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https://nardus.mpn.gov.rs/handle/123456789/19041
123456789-19041.pdf
yes
no
https://fedorabg.bg.ac.rs/fedora/get/o:25602/bdef:Content/download
no
Fiziološko prilagođavanje larvi gubara, Lymantria dispar L., i žutotrbe, Euproctis chrysorrhoea L., (Lepidoptera) na delovanje fluorantena
Physiological adjustment of larvae of gypsy moth, Lymantria dispar L., and brown-tail moth, Euproctis chrysorrhoea L., (Lepidoptera) to the effects of fluoranthene
[ "Mrdaković, Marija" ]
[ "Đurašević, Siniša", "Perić Mataruga, Vesna", "Mrdaković, Marija", "Đurašević, Siniša" ]
Filipović, Aleksandra
2022-05-25T07:03:22
[ "2022-05-25T07:03:22" ]
2021-12-06
[ "https://eteze.bg.ac.rs/application/showtheses?thesesId=8564", "https://fedorabg.bg.ac.rs/fedora/get/o:25602/bdef:Content/download", "https://plus.cobiss.net/cobiss/sr/sr/bib/56082441", "https://nardus.mpn.gov.rs/handle/123456789/19041" ]
[ "Fluoranten je jedan od najrasprostranjenijih policikličnih aromatičnih ugljovodonika, prisutan u lišću različitih biljaka kojima se hrane larve polifagnih vrsta insekata Lymantria dispar i Euproctis chrysorrhoea. Cilj ove doktorske disertacije je sticanje uvida u obrasce fizioloških odgovora larvi L. dispar i E. chrysorrhoea (Lepidoptera: Erebidae) na prisustvo sredinski relevantnih koncentracija fluorantena u hrani i rasvetljavanje mehanizama odbrane od njegovog štetnog delovanja, što doprinosi sagledavanju načina njihovog prilagođavanja stresnim uslovima u okruženju. Ispitivan je hronični uticaj dve koncentracije fluorantena (6,7 i 67 ng/g suve mase hrane) na larve L. dispar i E. chrysorrhoea, poreklom iz prirodnih populacija. Antioksidativni i detoksifikacioni enzimi srednjeg creva larvi su pokazali promene aktivnosti pod uticajem fluorantena, sa izraženijim odgovorima u tkivu srednjeg creva, kao i razlike u obrascima odgovora između vrsta. Uočeno je smanjenje ekspresije Hsp70 u celom srednjem crevu, a različiti odgovori Hsp70 u mozgu larvi. Kod obe vrste je došlo i do značajnih promena aktivnosti digestivnih enzima i njihovih izoformi u srednjem crevu larvi izlaganih fluorantenu. Detektovana je inhibicija aktivnosti određenih digestivnih enzima i njihovih izoformi kod larvi L. dispar, dok je kod larvi E. chrysorrhoea zabeleženo povećanje aktivnosti većeg broja enzima ove grupe, kao i ekspresija izoformi pojedinih enzima kod larvi izlaganih fluorantenu. Kanonijskom diskriminacionom analizom su potvrđene razlike između vrsta kada su u pitanju odgovori antioksidativnih i digestivnih enzima na prisustvo fluorantena u ishrani. Alokacija energetskih resursa ka mehanizmima odbrane, u prisustvu fluorantena, odrazila se na osobine životne istorije larvi obe vrste." ]
[ "Fluoranthene is one of the most abundant polycyclic aromatic hydrocarbons, present in the leaves of various plants used for food by larvae of polyphagous insect species Lymantria dispar and Euproctis chrysorrhoea. The aim of dissertation was to gain insight into the patterns of physiological responses of L. dispar and E. chrysorrhoea larvae (Lepidoptera: Erebidae) to the presence of environmentally relevant concentrations of fluoranthene in food and to elucidate the mechanisms of defense against its harmful effects, which contributes to perceive the way they adjust to stressful environmental conditions. Chronic effects of fluoranthene (6.7 and 67 ng/g dry food weight) on L. dispar and E. chrysorrhoea larvae, originating from natural populations, were examined. Antioxidative and detoxification enzymes of midgut showed changes of activity under the influence of fluoranthene, with more pronounced responses in midgut tissue, and between-species differences in patterns of responses. Decreased expression of Hsp70 in the midgut, and different responses of Hsp70 in the brain of larvae were noticed. Significant changes of the activity of digestive enzymes and their isoforms in the midgut of larvae of both species exposed to fluoranthene were noticed. Exposure to fluorantene inhibited the activity of certain digestive enzymes and their isoforms of L. dispar larvae, and increased the activity of a number of enzymes and expression of isoforms of certain enzymes of E. chrysorrhoea larvae. Canonical discriminant analysis confirmed between-species differences in responses of antioxidative and digestive enzymes to the presence of fluoranthene in the diet. The allocation of energy resources to defense mechanisms affected the life history traits of treated larvae of both species." ]
application/pdf
sr
Универзитет у Београду, Биолошки факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Београду
[ "Lymantria dispar L.", "Euproctis chrysorrhoea L.", "fluoranten", "antioksidativni enzimi", "detoksifikacioni enzimi", "Hsp70", "digestivni enzimi", "osobine životne istorije" ]
[ "Lymantria dispar L.", "Euproctis chrysorrhoea L.", "fluorantene", "antioxidative enzymes", "detoxification enzymes", "Hsp70", "digestive enzymes", "life history traits" ]
[ "Fiziološko prilagođavanje larvi gubara, Lymantria dispar L., i žutotrbe, Euproctis chrysorrhoea L., (Lepidoptera) na delovanje fluorantena" ]
[ "Physiological adjustment of larvae of gypsy moth, Lymantria dispar L., and brown-tail moth, Euproctis chrysorrhoea L., (Lepidoptera) to the effects of fluoranthene" ]
doctoralThesis
[ "BY-NC-ND" ]
Мрдаковић, Марија; Перић Матаруга, Весна; Ђурашевић, Синиша; Ђурашевић, Синиша; Мрдаковић, Марија; Филиповић, Aлександра;
[ "http://nardus.mpn.gov.rs/bitstream/id/142798/Izvestaj_Komisije_12203.pdf", "http://nardus.mpn.gov.rs/bitstream/id/142797/Disertacija_12203.pdf", "https://fedorabg.bg.ac.rs/fedora/get/o:25602/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_19041" ]
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https://nardus.mpn.gov.rs/handle/123456789/19066
123456789-19066.pdf
yes
no
http://nardus.mpn.gov.rs/bitstream/id/142872/Disertacija_12237.pdf
no
Procena ekostatusa rečnih sistema na primeru dunavskog basena primenom modela veštačkih neuronskih mreža
Prediction and assessment of Danube river basin ecostatus by applying Model of ArtificialNeural Networks
[ "Vojinović-Miloradov, Mirjana", "Radulović, Snežana" ]
[ "Mihajlović, Ivana", "Kovačević, Srđan", "Cvijanović, Dušanka", "Vukmirović, Srđan", "Savić, Dragan", "Radulović, Snežana", "Vojinović-Miloradov, Mirjana" ]
Krtolica, Ivana
2022-05-25T18:23:20
[ "2022-05-25T18:23:20" ]
2021-11-23
[ "https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija163032381942723.pdf?controlNumber=(BISIS)118126&fileName=163032381942723.pdf&id=18248&source=NaRDuS&language=sr", "https://www.cris.uns.ac.rs/record.jsf?recordId=118126&source=NaRDuS&language=sr", "https://www.cris.uns.ac.rs/DownloadFileServlet/IzvestajKomisije163032390904746.pdf?controlNumber=(BISIS)118126&fileName=163032390904746.pdf&id=18249&source=NaRDuS&language=sr", "https://nardus.mpn.gov.rs/handle/123456789/19066" ]
[ "Osnovni cilj doktorske disertacije je kreiranje modela za predikciju ekolopkog statusa rečnih basena na osnovu prisustva makrofita i ključnih, reprezentativnih hemijskih parametara na primeru Dunava primenom veštačkih neuronskih mreža i eko-prijateljski orijentisanih metodologija. S obzirom na to da biološki i fizičko - hemijski parametri koji se prema Okvirnoj Direktivi o vodama koriste za procenu ekološkog statusa vodnih ekosistema ne pokazuju međusobnu linearnu zavisnost modeli veštačkih neuronskih mreža suoptimalan alat za procenu ekostatusa akvatičnih sistema. Osnovni motiv istraživanja je obrada podataka prikupljena tokom poslednjeg istraživanja Dunava (engl.Joint Danube Survey 3) u cilju procene ekološkog statusa Dunava u celini. Rezultati modelovanja potvrdili su da je kreiran model veštaćkih neuronskih mreža odgovarajući alat za procenu i predikciju ekološkog statusa rečnih ekosistema kada se kao ulazni parametri koriste vrednosti zastupljenosti makrofita, a kao izlazni podaci klase ekološkog statusa izračunate na osnovu izmerenih koncentracija rastvorenog kiseonika, nitratnih i ortofosfatnih anjona. U cilju određivanja signifikantnih vrsta makrofita korišćenih u modelovanju primenjena je analiza osetljivosti. Pristup interkorelacije makrofita, kao ulaznih varijabli, i selektovanih reprezentativnih hemijskih parametara primenom modela veštačkih neuronskih mreža po prvi put je apliciran u istraživačkim aktivnostima doktorske disertacije." ]
[ "The aim of doctoral dissertation Prediction and assessment of Danube river basin ecostatus by applying model of Artificial Neural Networks is creating model of artificial neural network for predicting eco status of river basins using macrophytes and key, representative chemical parameters have no linear correlation Artificial Neural Networks were shown as adequate tool for modelling river eco status. Main motive for investigation is data processing of dataset collected during Joint Danube Survey 3 expedition in aim to predict the whole Danube River basin eco status. Modelling results claimed that created model of Artificial Neural Networks is appropriate tool for prediction river eco status when inputs variables are macrophytes and outputs are classes of ecological state calculated according to measured concentrations of dissolved oxygen, nitrate and orthophosphate anions. This kind of artificial intelligence modelling for prediction and assessment of Danube River basin eco status. Modelling results claimed that model of Artificial Neural Networks is appropriate tool for prediction river eco status when inputs variables are macrophytes and outputs are classes of ecological state calculated according to measured concentrations of dissolved oxygen, nitrate and orthophosphate anions. This kind of artificial intelligence modelling for prediction and assessment of Danube river basin ecostatus for the first time was applied in PhD thesis." ]
sr (latin script)
Универзитет у Новом Саду, Факултет техничких наука
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc/4.0/" ]
Универзитет у Новом Саду
[ "Ekološki status akvatičnih rečnih sistema", "dunavski basen", "rastvoreni kiseonik", "nitratni anjoni", "ortofosfatni anjoni", "veštačke neuronske mreže", "Kapa indeks", "analizaosetljivosti", "Mann – Whitney test" ]
[ "Aquatic river system ecostatus", "Danube basin", "dissolved oxygen", "nitrate anions", "ortophosphateanions", "Artificial Neural Networks", "Kappa index", "Sensitivity analysis", "Mann – Whitney test" ]
[ "Procena ekostatusa rečnih sistema na primeru dunavskog basena primenom modela veštačkih neuronskih mreža" ]
[ "Prediction and assessment of Danube river basin ecostatus by applying Model of ArtificialNeural Networks" ]
doctoralThesis
[ "BY-NC" ]
Радуловић, Снежана; Војиновић-Милорадов, Мирјана; Михајловић, Ивана; Ковачевић, Срђан; Цвијановић, Душанка; Вукмировић, Срђан; Савић, Драган; Радуловић, Снежана; Војиновић-Милорадов, Мирјана; Кртолица, Ивана; Процена екостатуса речних система на примеру дунавског басена применом модела вештачких неуронских мрежа; Процена екостатуса речних система на примеру дунавског басена применом модела вештачких неуронских мрежа;
[ "http://nardus.mpn.gov.rs/bitstream/id/142872/Disertacija_12237.pdf", "http://nardus.mpn.gov.rs/bitstream/id/142873/Izvestaj_komisije_12237.pdf", "https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija163032381942723.pdf?controlNumber=(BISIS)118126&fileName=163032381942723.pdf&id=18248&source=NaRDuS&language=sr" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_19066" ]
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https://nardus.mpn.gov.rs/handle/123456789/18966
123456789-18966.pdf
yes
no
no
"КЛАН" - сценарио за играну криминалистичку ТВ серију, формат ongoing serial програма
[ "Кољевић, Срђан" ]
[ "Милосављевић, Ђорђе", "Milin, Boško", "Стојковић, Мирко", "Рапајић, Светозар" ]
Михајловић, Даријан
2022-02-25T14:09:01
[ "2022-02-25T14:09:01" ]
2021-12-28
[ "http://eteze.arts.bg.ac.rs/handle/123456789/516", "https://nardus.mpn.gov.rs/handle/123456789/18966" ]
[ "" ]
[ "U svetu televizijskog programa, u današnje vreme, teško je zamisliti šta bi se novo moglo rećina planu serijalnog programa. U ovom radu ćemo putem analize raznih serijskih, kao i serijalnih programa, kako kod nas,tako i u svetu, istražiti dramsku strukturu serija, sličnosti u strukturi sa filmom i pozorištem,kao i osnovne razlike kako u diegetskom svetu, tako i u načinu pripovedanja. Dok se ovaj rad stvara, srpski serijski program doživljava najveću ekspanziju u svojoj istoriji. Serije su postale glavni dramski program i ako je sudeći po angažmanu glumaca, osvojile su u potpunosti ludički prostor Balkana. Postoji određeni broj serija koje su transkulturalne adaptacije Urgentni centar(2014-) je razvijen iz serije E.R (1994-2009), zatim Andrija i Anđelka (2015-) iz serije Un gars, una file (1999-2003), Los Serrano (2003-2008) su Sinđelići(2013-) , kao i ostatak serijskog programa koji je originalan, daje nam široku mogućnost istraživanja različitih žanrovskih obrazaca, kao i analizu regionalnih projekata, koji su pripremani po uzoru na neke skandinavske produkcije, srpska Besa (2018-) i švedsko- danski Most (2011-2108), kao i preuzimanjem franšize i njenim adaptiranjem za zemlje u regionu, već pomenuti Sinđelići i hrvatska adaptacija Horvatovi (2015-). Publika stvara različite fandom (fan domination) grupe, te nas to vodi do toga da se pozabavimo i samom publikom i njenim doprinosom razvoju same strukture. Na kraju, kao uvod u završeni scenario prvih pet epizoda, predstavićemo produkcionu bibliju, kao sažetak gotovog projekta, spremnog za ekranizaciju.", "Nowadays in the world of television programming it is difficult to conceive what new could be said with respect to serial TV programme. Since the beginnings of television, the serial drama program was constantly present to a greater or lesser extent, but it was differently valued. This paper analyses various serial programs, produced both domestically in Serbia and abroad with an aim to examine the dramatic structure of series, similarities in structure with film and theatre, as well as basic differences both in diegetic worlds and in narratives of television, theatre and film. As this paper is drafted, the Serbian serial program is experiencing the greatest expansion in history. The series have became the programming cornerstone of every Serbian TV station and if observed against the backdrop of actors’ engagement, have completely conquered the ludic space of the Balkans. A certain number of these series are transcultural adaptations. Urgentni centar (2014-) was developed from E.R. (1994-2009), Un gars, una fille (1999-2003) was adapted into Andrija i Anđelka (2015-), while Los Serrano (2003-2008) are Sinđelići (2013-). Combined with the original serial programme, we are given an opportunity to research genre patterns from foreign markets when adapted to a new audience, alongside an analysis of regional projects, which are prepared based on the model of some Scandinavian productions, such is the case of the Serbian Besa (2018-) and Swedish-Danish The Bridge (Bron, Broen 2011-2018). The paper also considers franchises, which are spread and adapted regionally such as the above mentioned Serbian TV series Sindjelici and the Croatian derivate Horvatovi (2015-). The audience creates various fandom (fan domination) groups. For this reason, the paper also looks into the audience and its contribution to the development of the story structure itself. Finally, as an introduction to a completed script of the first five episodes, we will present the production bible, as a summary of the completed project." ]
Универзитет уметности у Београду, Факултет драмских уметности
[ "" ]
[ "openAccess" ]
[ "" ]
Универзитет уметности у Београду
[ "" ]
[ "serijalni program", "serial program", "nestala lica", "regionalna serija", "istorija tv programa", "serije i filmovi", "serije i pozorište.", "Serbian series", "missing persons", "regional series", "history of TV programs", "series and films", "series and theatre" ]
[ "\"КЛАН\" - сценарио за играну криминалистичку ТВ серију, формат ongoing serial програма" ]
[ "" ]
other
[ "" ]
Koljević, Srđan; Milosavljević, Đorđe; Rapajić, Svetozar; Milin, mr Boško; Stojković, dr um. Mirko; Mihajlović, Darijan; "KLAN" - scenario za igranu kriminalističku TV seriju, format ongoing serial programa;
[ "http://nardus.mpn.gov.rs/bitstream/id/142423/bitstream_142423.pdf", "http://nardus.mpn.gov.rs/bitstream/id/142424/bitstream_142424.pdf" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_18966" ]
sc
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https://nardus.mpn.gov.rs/handle/123456789/18965
123456789-18965.pdf
yes
no
no
Режија представе "Калигула" по комаду Албера Камија (Истраживање феномена апсурда у креирању редитељског поступка у савременом позоришту)
[ "Рапајић, Светозар" ]
[ "Вујић, Ивана", "Стефановић, Бранислава", "Павловић, Милош", "Милин, Бошко" ]
Тришић, Снежана
2022-02-25T14:09:00
[ "2022-02-25T14:09:00" ]
2021-10-21
[ "https://we.tl/t-O5DhoZGQCh", "http://eteze.arts.bg.ac.rs/handle/123456789/511", "https://nardus.mpn.gov.rs/handle/123456789/18965" ]
[ "" ]
[ "Predmet mog istraživačko-umetničkog rada i ove disertacije: „Istraživanje fenomena apsurda u kreiranju rediteljkog postupka u savremenom pozorištu” – utemeljen je na režiji predstave Kaligula, po drami Albera Kamija u Narodnom pozorištu u Beogradu, koja je premijerno izvedena 05.02.2020. godine. Ta predstava je glavni predmet istraživanja i analize, kao i osnovno polazište i cilj ove disertacije. Autentičan metodološki pristup i zaključke probala sam da sprovedem i proverim i kroz analizu relevantnih svetskih predstava u savremenom pozorištu u prvom, uvodnom, delu rada. Kroz analizu sadržinskih i formalnih sličnosti i razlika među dramama koje se smatraju ključnim delima teatra apsurda, kao i kroz analizu filozofskog pojma – apsurd, probala sam da pronađem i definišem osnovne principe, elemente, sredstva i metodologiju rediteljskog postupka u ovoj oblasti i primenim ih u režiji predstave Kaligula. Cilj ovog rada je da apsurd kao filozofsku i apstraktnu kategoriju približim publici kroz konkretna i specifična rediteljska sredstva, kao i da pronađem njegove komunikacijske kodove za publiku. Namera mi je da u analizi i postavci apsurda na sceni, principom suptilne aktuelizacije, dekonstrukcije, citatnosti kroz audio-vizuelnu inscenaciju i rediteljski postupak, istražim i scenski izrazim fenomen apsurda u kontekstu savremenog društva, čoveka i pozorišta. U prvom delu rada poseban fokus stavila sam na rediteljski postupak u savremenom pozorištu, gde kroz razlličite relevantne primere savremenog pozorišta izvodim, raščlanjujem i preispitujem elemente svog metodološkog pristupa kojim ću se kasnije detaljno baviti na primeru predstave Kaligula u trećem i četvrtom delu rada. U prvom delu bavila sam se značajem, mogućnostima i osnovnim elementima rediteljskog postupka u pozorišnoj režiji, kao i definisanjem pojma „savremeno“ pozorište i „rediteljski postupak“. Faze realizacije rediteljskog postupka predstavljaju uvod u sledeći deo rada u kome se podrobnije bavim fenomenom – apsurda. U drugom delu rada kroz analizu života i dela pisca Albera Kamija, njegovog opusa, kao i filozofskog i dramskog pravca kojima pripada, istražujem i fenomen apsurda. U ovom delu rada osvrćem se na četiri pravca važna za analizu apsurda: egzistencijalizam, filozofska drama, filozofija apsurda, drama i pozorište aspurda. Kroz njih izvodim ključne elemente za razumevanje, prepoznavanje i realizaciju apsurda na sceni jer kroz ovaj umetničko-istraživački proces i predstavu želim da uspostavim apsurd kao jedan od najznačajnijih fenomena savremenog doba, moderne umetnosti i pozorišta. U trećem delu razmatram metodologiju i faze rada, ali i uspostavljam postupak uz pomoć kojeg prelazim sa dramskog teksta i istorijskog konteksta na stvaralački deo predstave Kaligula. Kroz tumačenje naslova, bavim se analizom i kreacijom naslovne uloge komada, a zatim to dovodim u vezu sa tumačenjem i postavkom cele predstave u savremenom kontekstu. U ovom delu sagledavam lik Kaligule iz različitih perspektiva i izdvajam najznačajniju građu za celokupno kreiranje glavne uloge, kao i cele predstave. U četvrtom delu razmatram apsurd kroz nastanak, razvoj i postavku jednog odabranog rediteljskog postupka. U ovom delu bavim se analizom osnovnih elemenata drame kroz definisanje i tumačenje osnovnih kategorija pozorišne režije: teme, ideje, sukoba. U ovom delu uglavnom se fokusiram na stvaralački deo rediteljskog rada i procesa, pa samim tim on predstavlja centralni i najvažniji deo ovog rada. Probala sam da izvedem i prikažem jedan mogući metodološki pristup kreiranja rediteljskog, a u ovom slučaju i rediteljskoscenografskog postupka. U petom delu kroz zaključna razmatranja navodim osnovne faze praktičnog rada. Tu izdvajam određene elemente koji su mi koristili u radu i komunikaciji sa sardanicima i glumcima u svim fazama. Uz to prilažem autentičnu prepisku, materijal koji dokumentuje trag zajedničkog stvaranja i procesa, kao primer i put ka razjašnjenju, razradi i osmišljavanju glavne scene u komadu. U ovom delu izvodim zaključke koji su nastali u odnosu na proces i rezultat rada, kao i njegov prijem kod publike i kritike, a sve to u cilju preispitivanja prepoznatljivosti, čitljivosti, dometa i dejstva rediteljskog postupka i apsurda, koji su razmatrani ovom u radu i uspostavljeni u predstavi. Istražujući genezu nastanka i razvoj apsurda u filozofskoj i dramskoj literaturi, kao i njegov veliki značaj i uticaj na određene savremene rediteljske poetike i pravce, savremenu dramu i pozorište, umetnički deo mog doktorskog rada bazirala sam na režiji predstave Kaligula, po istoimenoj drami Albera Kamija. Ova disertacija nastala je zahvaljujući iskustvu, istraživanju i umetničko-praktičnom procesu koji sam prošla sa autorskim timom, glumcima i saradnicima, kao i ozbiljnoj produkciji i podršci Narodnog pozorišta u Beogradu. Zajednički rad, znatiželja, podrška, posvećenost i kreativnost veoma su uticali na istraživačko-umetničke domete celokupnog rada i ove doktorske disertacije.", "The subject of my artistic research and this dissertation: “Exploring the phenomenon of absurdity in creating a directing procedure in contemporary theater” – is based on the directing of the play Caligula, based on the play by Albert Camus at the National Theater in Belgrade, which premiered on 5th February 2020. This play is the main subject of my research and analysis, as well as the basic starting point and the aim of this dissertation. In the first, introductory part of this thesis, I tried to implement and verify the authentic methodological approach and conclusions through the analysis of relevant world plays in contemporary theater. Through the analysis of content and formal similarities and differences between plays considered to be key works of the theater of the absurd, as well as through the analysis of the philosophical concept – the absurd, I tried to find and define basic principles, elements, means and methodology of directing in this field, and to apply them while directing Caligula. The aim of this work is to bring the absurd as philosophical and abstract category closer to the audience through concrete and specific directing tools, as well as to find its communication codes for the audience. My intention is to, by analyzing and setting of the absurd on the stage, through the principle of subtle actualization, deconstruction, citation through audio-visual staging and directing, explore and present the phenomenon of the absurd in the context of modern society, man and theater. In the first part of the paper, I put a special focus on the directing procedure in contemporary theater, where through various relevant examples I derive, analyze, and review elements of my methodological approach, which I later develop in detail on the example of Caligula in the third and fourth part. The focus of the first part is on the meaning, possibilities, and basic elements of the directing procedure in theater, as well as on defining the term ‘contemporary’ theater and ‘directing procedure’. The stages of realization of the directing procedure represent an introduction to the next part of the work in which I treat in more detail the main phenomenon – the absurd. In the second part of the paper, through the analysis of the life and work of the writer Albert Camus, his opus, as well as the philosophical and theater movement to which he belongs, I also explore the phenomenon of the absurd. In this part I look at four movements important for the analysis of the absurd: existentialism, philosophical drama, philosophy of the absurd, drama and the theater of the absurd. Through them I derive key elements for understanding, recognizing and realizing the absurd on the stage, because through this artistic research process and deduction I want to establish the absurd as one of the most important phenomena of the modern times, modern art and theater. In the third part I discuss the methodology and phases of the work, but I also establish the procedure which allow the move from dramatic text and the historical context to the creative part of the play Caligula. Through the interpretation of the title, I deal with the analysis and creation of the leading role in the play and then I connect that with the interpretation and setting of the whole play in a contemporary context. In this part I look at the character of Caligula from different perspectives and single out the most important material for the overall creation of the protagonist role as well as the entire play. In the fourth part I discuss the absurd through the origin, development and setting of a selected directing procedure. In this part I provide the analysis of the basic elements of drama through the definition and interpretation of the basic categories of theater directing: themes, ideas, conflicts. In this part I mainly focus on the creative part of the director’s work and process so it represents the central and most important part of this work. I tried to derive and present one possible methodological approach to creating a directing procedure and, in this case, a directing scenography procedure. In the fifth part through concluding remarks I list the basic phases of practical work. Here I single out certain elements that I found useful throughout my working process and communication with co-workers and actors during all phases. In addition, I enclose authentic correspondence, the material that documents traces of joint creation and process, as an example and a way towards the clarification, elaborating and devising of the main scene in the play. In this part I draw conclusions concerning the process and the result of the work, as well as its reception by the audience and the critics in order to review the recognition, readability, scope and effect of the directing procedure and absurdity established in the play. Exploring the genesis and development of the absurd in philosophical and dramatic literature as well as its great significance and influence on certain contemporary directing poetics and movements, contemporary drama and theater, I based the artistic part of my doctoral work on the play Caligula, based on the play of the same name by Albert Camus. This dissertation was created thanks to the experience, research and artistic and practical process that I went through with the author’s team, actors and collaborators, as well as the serious production and support of the National Theater in Belgrade. Joint effort, curiosity, support, dedication and creativity have greatly influenced the research and artistic achievements of the entire working process and this doctoral dissertation." ]
Универзитет уметности у Београду, Факултет драмских уметности
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[ "openAccess" ]
[ "" ]
Универзитет уметности у Београду
[ "" ]
[ "pozorišna režija", "theater directing", "directing procedure", "absurd", "existentialism", "theater of the absurd", "Albert Camus", "Caligula", "contemporary theater", "rediteljski postupak", "apsurd", "egzistencijalizam", "pozorište apsurda", "Alber Kami", "Kaligula", "savremeno pozorište" ]
[ "Режија представе \"Калигула\" по комаду Албера Камија (Истраживање феномена апсурда у креирању редитељског поступка у савременом позоришту)" ]
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other
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Rapajić, Svetozar; Vujić, Ivana; Stefanović, Branislava; Pavlović, Miloš; Milin, Boško; Trišić, Snežana; Režija predstave "Kaligula" po komadu Albera Kamija (Istraživanje fenomena apsurda u kreiranju rediteljskog postupka u savremenom pozorištu);
[ "http://nardus.mpn.gov.rs/bitstream/id/142421/bitstream_142421.pdf", "http://nardus.mpn.gov.rs/bitstream/id/142420/bitstream_142420.pdf" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_18965" ]
sc
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https://nardus.mpn.gov.rs/handle/123456789/20632
123456789-20632.pdf
yes
no
https://fedorabg.bg.ac.rs/fedora/get/o:26334/bdef:Content/download
no
Production of hydrollytic enzymes by fermentation on agricultural by-products using Bacillus sp.
Proizvodnja hidrolitičkih enzima fermentacijom na poljoprivrednom otpadu pomoću različitih vrsta iz roda Bacillus
[ "Knežević-Jugović, Zorica" ]
[ "Mojović, Ljiljana", "Antov, Mirjana", "Luković, Nevena", "Šekuljica, Nataša" ]
Salim, Abdalla Ali
2022-09-06T14:03:11
[ "2022-09-06T14:03:11" ]
2021-05-26
[ "https://uvidok.rcub.bg.ac.rs/bitstream/handle/123456789/3854/Referat.pdf", "https://eteze.bg.ac.rs/application/showtheses?thesesId=8746", "https://fedorabg.bg.ac.rs/fedora/get/o:26334/bdef:Content/download", "https://plus.cobiss.net/cobiss/sr/sr/bib/70924297", "https://nardus.mpn.gov.rs/handle/123456789/20632" ]
[ "During the production and processing of food, large quantities of waste are generated which need to be properly stored and, at best, found new use and utilized. An extremely large problem worldwide is certainly the large amount of agroindustrial waste that is generated on a daily and especially annual basis. If agroindustrial waste is directly stored in the environment, it causes a greenhouse effect and is a large-scale environmental problem. However, agroindustrial waste has recently been regarded as an extremely valuable raw material that can be converted into an added-value raw material by applying different biotechnological approaches. Accordingly, this doctoral dissertation deals with the global problem of utilization and quality improvement of various agro-industrial wastes through the application of biotechnology. Modification and improvement of quality is achieved by growing the production microorganism on a solid surface, that is, agroindustrial waste. This is a rather new method which involves the use of cheap materials but they usually contain large amount of protein, sugar and mineral as well as bioactive compounds such as polyphenols, carotenoids and dietary fibers. Accordingly, the first part of this doctoral dissertation is the selection of the microorganism producer. During the selection, a rich collection of various commercial and natural bacterial strains was utilized, which is available at the Department of Biochemical Engineering and Biotechnology, Faculty of Technology and Metallurgy. Various strains have been tested for the ability to produce α-amylase, cellulase, pectinase and protease using selective medium on agar plates. In this way, one of the Bacillus strains was found to be particularly prominent in the production of targeted enzymes. Due to the fact that this strain is a natural isolate, identification by sequencing 16SrRNA encoding gene and subsequent analysis of the obtained sequence using the BLAST (Basic Logical Alignment Search Tool) was performed. Further, the obtained and isolated strain (Bacillus sp. TMF-1) was used in the solid-state fermentation process with the main objective to examine the possibility of the selected microorganism to produce desired enzymes under the different substrate:water ratios by using different types of agroindustrial waste materials such as wheat bran, soybean meal, olive oil cake, sunflower meal for growth. Following the cultivation of microorganism producer and production of targeted enzymes, it has been found that agro-industrial waste can be transferred to an even better growing medium if a certain treatment of the raw material is carried out. Accordingly, the aforementioned agroindustrial wastes have been chemically treated by the use of acids and bases, the use of ultrasound as well as microwave technology and used for enzymes production by Bacillus sp. TMF-1." ]
[ "U toku proizvodnje i obrade hrane stvaraju se velike količine otpada koje je neophodno skladištiti na pravi način i u najboljem slučaju ponovo iskoristiti. Izuzetno veliki problem širom sveta je svakako stvaranje velikih količina agro-industrijskog otpada na dnevnom a naročito godišnjem nivou. Ukoliko se agro-industrijski otpad direktno skladišti u okolnu životnu sredinu nastaje efekat staklene bašte i to je ekološki problem velikih razmera. Međutim, agro-industrijski otpad je skoro klasifikovan kao izuzetno vredna sirovina koja se može prevesti u sirovinu sa dodatnom vrednošću primenom različitih biotehnoloških pristupa. Shodno tome, ova doktorska disertacija se bavi globalnim problemom iskorišćenja i unapređenja kvaliteta različitog agroindustrijskog otpada primenom biotehnologije. Modifikacija i unapređenje kvaliteta je postignuta gajenjem proizvodnog mikroorganizma na čvrstoj podlozi, tj. agro-industrijskom otpadu. Ovo je prilično nova metoda koja podrazumeva upotrebu jeftinih materijala koji sadrže velike količine proteina, šećera i minerala kao i bioaktivnih jedinjenja kao što su polifenoli, karotenoidi i dijetetska vlakna. Prvi deo ove doktorske disertacije je selekcija mikroorganizma producenta. Tokom ove selekcije upotrebljena je bogata kolekcija različitih prirodnih i komercijalnih sojeva bakterija dostupnih na Katedri za Biohemijsko inženjerstvo i biotehnologiju, Tehnološko-metalurškog fakulteta. Različiti sojevi su ispitani na sposobnost proizvodnje α-amilaza, celulaza, pektinaza i proteaza korišćenjem selektivnog medijuma na agar pločama. Na ovaj način utvrđeno je da jedan od Bacillus sojeva ima izuzetan potencijal za proizvodnju ciljanih enzima. Shodno činjenici da je ovaj soj prirodnog porekla, izvršena je identifikacija sekvencionisanjem gena za kodiranje 16SrRNA i naknadnom analizom dobijene sekvence korišćenjem osnovnog alata za pretraživanje logičkog poravnanja (na engl.’’ Basic Logical Alignment Search Tool’’, BLAST). Zatim, dobijeni i izolovani soj (Bacillus sp. TMF-1) je korišćen za fermentaciju na čvrstoj podlozi sa osnovnim ciljem da se ispita mogućnost odabranog mikroorganizma da proizvede željene enzime pri različitom odnosu supstrat:voda korišćenjem za rast različitog agro-industrijskog otpadnog materijala kao što su: pšenične mekinje, sojina sačma, pogača nakon ceđenja maslinovog ulja, suncokretova sačma. Praćenjem gajenja mikroorganizma producenta i proizvodnje ciljanih enzima, utvrđeno je da se agroindustrijski otpad može prevesti u još bolji medijum za rast ukoliko se sirovine podvrgnu određenim pretretmanima. Prema tome, pomenuti agro-industrijski otpadi su pretretirani hemijski korišćenjem kiselina i baza ali i primenom tehnologije ultrazvuka i mikrotalasa i korišćeni za proizvodnju enzima Bacillus sp. TMF-1-om." ]
application/pdf
sr
Универзитет у Београду, Технолошко-металуршки факултет
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[ "openAccess" ]
[ "" ]
Универзитет у Београду
[ "hydrolytic enzymes production", "soli-state ferementation", "agroindustrial waste", "antinutritional factors", "biological activity" ]
[ "proizvodnja hidrolitičkih enzima", "fermentacija na čvrstoj podlozi", "agroindustrijski otpad", "antinutritivni faktori", "biološka aktivnost" ]
[ "Production of hydrollytic enzymes by fermentation on agricultural by-products using Bacillus sp." ]
[ "Proizvodnja hidrolitičkih enzima fermentacijom na poljoprivrednom otpadu pomoću različitih vrsta iz roda Bacillus" ]
doctoralThesis
[ "" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/145484/Izvestaj_Komisije_12451.pdf", "http://nardus.mpn.gov.rs/bitstream/id/145483/Disertacija_12451.pdf", "https://fedorabg.bg.ac.rs/fedora/get/o:26334/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_20632" ]
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https://nardus.mpn.gov.rs/handle/123456789/20614
123456789-20614.pdf
yes
no
http://nardus.mpn.gov.rs/bitstream/id/157649/Disertacija.pdf
no
Запис’ Цветног трга – визуелни идентитет; примена аналогног поступка као посебне вредности у графичком дизајну постиндустријског доба
[ "Блажина, Зоран А." ]
[ "Bočina, Ranko N.", "Вељовић, Ивана, Д.", "Лађушић, Марко Р.", "Ђуровић, Божидар" ]
Никодиновић, Драгица Љ.
2022-09-06T10:31:39
[ "2022-09-06T10:31:39" ]
2022-06-10
[ "http://eteze.arts.bg.ac.rs/handle/123456789/550", "https://nardus.mpn.gov.rs/handle/123456789/20614" ]
[ "" ]
[ "Докторски уметнички пројекат ”Запис” Цветног трга – визуелни идентитет; примена аналогног поступка као посебне вредности у графичком дизајну постиндустријског доба, представља новопројектовани визуелни идентитет градског трга израђен и примењен у комбинацији аналогних и дигиталних техника рада, презентован кроз књигу графичких стандарда, пратеће радове и плакате приказане на изложби. Циљ овог рада је да покаже због чега и на које начине аналогни поступак представља додатну вредност у дигиталном добу где софтвер заузима значајно место у креирању и реализацији пројеката графичког дизајна. Теоријско полазиште се ослања на текстове водећих теоретичара нових медија, у којима образлажу свој став, због чега се ми као друштво нисмо одрекли аналогног поступка у стваралаштву. Ово поглавље има циљ да прикаже истраживања, обухвати материјале и укаже на чињенице и запажања о постиндустријском периоду. Бави се предностима и манама аналогног и дигиталног поступка рада у графичком дизајну, обећањима које нам даје развој технологије, софтвера и нових медија, наводећи савремене проблеме стварања оригинала и приказујући студије који се односе на питања идентитета у дигиталном добу. Посебна пажња је посвећена истраживању историје локације Цветни трг од средине деветнаестог века до данас, анализирајући његове фазе развоја као урбаног топонима заједно са социолошким аспектима који су обликовали ово место као минијатурну градску агору. У практичном делу рада, инспирисан историјом и симболима Цветног трга, створен је асоцијативан лого вишеструког значења, служећи се предностима оба принципа рада. Лого представља основу за стварање визуелног идентитета Цветног трга, који је приказан у оквиру књиге графичких стандарда и кроз пратеће радове на изложби докторског уметничког пројекта. Полазећи од чињенице да су графичке комуникације једно од најмоћнијих средстава савремене комуникације, постојала је неопходност да примена идентитета добије и проширену функцију. Поред обавезних сегмената које књига графичких стандарда треба да садржи, визуелни идентитет је презентован и на примерима у јавном простору, кроз пратеће промотивне материјале и предлоге за промовисање догађаја од општег значаја." ]
Универзитет уметности у Београду, Факултет примењених уметности
[ "" ]
[ "openAccess" ]
[ "" ]
Универзитет уметности у Београду
[ "" ]
[ "Визуелни идентитет", "трг", "храст", "аналогно", "дигитално", "додатна вредност", "цветни трг", "јавни простор", "симболи", "заштитни знак", "постиндустријско доба" ]
[ "Запис’ Цветног трга – визуелни идентитет; примена аналогног поступка као посебне вредности у графичком дизајну постиндустријског доба" ]
[ "" ]
other
[ "" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/157650/Izvestaj.pdf", "http://nardus.mpn.gov.rs/bitstream/id/157649/Disertacija.pdf" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_20614" ]
sc
[ "" ]
[ "" ]
[ "" ]
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https://nardus.mpn.gov.rs/handle/123456789/20606
123456789-20606.pdf
yes
no
http://nardus.mpn.gov.rs/bitstream/id/157636/Disertacija.pdf
no
Воз браће Лимијер, употреба виртуелних технологија у изради дигиталне сценографије - интерактивна инсталација
[ "Драговић, Јасна, С." ]
[ "Bočina, Ranko N.", "Ћирић, Растко, М.", "Сопић, Јелена, М.", "Стојковић, Мирко" ]
Радошевић, Михаило Д.
2022-09-06T10:31:32
[ "2022-09-06T10:31:32" ]
2022-04-21
[ "http://eteze.arts.bg.ac.rs/handle/123456789/536", "https://nardus.mpn.gov.rs/handle/123456789/20606" ]
[ "" ]
[ "Тема докторског уметничког пројекта Воз браће Лимијер, Употреба виртуелних технологија у изради дигиталне сценографије – интерактивна инсталација је разматрање утицаја савремених технологија на филмску индустрију, a пре свега на сценографију и заснива се на креирању дигиталне сценографије и њеној виртуелној конзумацији од стране публике. Полазна тачка овог рада је осврт на развој филмског медија кроз историју, почетне филмске експерименте, формирање филмског језика као и појављивање савремених технологија које утичу на сам начин израде филма, а чији се корени налазе у техникама које су развиле авангарде двадесетих година прошлог века. Иако се процес стварања филма развијао и унапређивао кроз деценије, конзумација филмског дела је остала релативно иста. Убрзан развој технологије на пољу виртуелне реалности и њена широка доступност данас, омогућава да се од гледаоца створи активни учесник у филмском делу са квалитативно потпуно новим доживљајем. Дефинисањем основних појмова виртуелне реалности, правила и параметара одређује се планска процедура који обезбеђује успешност финалног продукта, њен развојни пут, од идеје до реализације, а потом и њену експерименталну и практичну примену у индустрији забаве, а шире и за потребе других области где ће ВР технологије наћи своју улогу. Како би се испитала теза до које мере ВР шири спектар корисничког искуства конзумента успостављен је модел као тематска интерактивна инсталација омажа браћи Лимијер. Овај модел треба да послужи за процену домета трансформације гледаоца у активног учесника и његовог квалитета доживљаја, као и да покаже да је ВР неодвојиви део објективне реалности. У фокусу рада је дигитални облик ВР сценографије као интегришући фактор филмског производа и њена интеракција са корисником и његовим проширеним искуством чиме се отвара полигон за нова теоријска разматрања, експерименте у пракси и едукацију на том плану." ]
Универзитет уметности у Београду, Факултет примењених уметности
[ "" ]
[ "openAccess" ]
[ "" ]
Универзитет уметности у Београду
[ "" ]
[ "филм", "сценографија", "виртуелна реалност", "браћа Лимијер", "савремене технологије", "софтвер", "дигитални медији", "процес израде", "интернет", "тродимензионални простори", "имерсивност", "Аутодеск 3Дс Макс", "Пиксолоџик ЗиБраш", "Адобе Сабстнс 3Д", "Ефир Орнатрикс", "Врлд Машин", "Марвелус Дизајнер", "Анрил Енџин", "Ризом УВ" ]
[ "Воз браће Лимијер, употреба виртуелних технологија у изради дигиталне сценографије - интерактивна инсталација" ]
[ "" ]
other
[ "" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/157637/Izvestaj.pdf", "http://nardus.mpn.gov.rs/bitstream/id/157636/Disertacija.pdf" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_20606" ]
sc
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https://nardus.mpn.gov.rs/handle/123456789/20602
123456789-20602.pdf
yes
no
http://nardus.mpn.gov.rs/bitstream/id/157629/Disertacija.pdf
no
КРЕВЕТ ЗА ТРОЈЕ Интерактивна позоришна представа по мотивима истоимене драме Милорада Павића
[ "Вујић Коминац, Ивана" ]
[ "Правдић, Иван", "Берберовић, Миланка", "Рапајић, Светозар", "Јованић, Александра" ]
Томић, Ивана
2022-09-06T10:31:11
[ "2022-09-06T10:31:11" ]
2022-02-28
[ "http://eteze.arts.bg.ac.rs/handle/123456789/542", "https://nardus.mpn.gov.rs/handle/123456789/20602" ]
[ "" ]
[ "Докторски уметнички пројекат „Кревет за троје“, реализован у форми позоришне представе, бави се критиком патријархалног система, положаја жене, питањем брака и породице данас. Инспирисан истоименом драмом Милорада Павића, аутор се у овом раду осврће и на Павићеву књижевност, хипертекст и ергодичку књижевност. Појам хипертекста повезује се са хипердрамом и интерактивним позориштем. Представа „Кревет за троје“ реализована је у духу интерактивности и позива се на праксе интерактивног позоришта у 20. и 21.веку. Тема пројекта обрађена је теоретски са више аспеката – психолошког, филозофског, социолошког, религијско-митолошког и астролошког. У психолошком приступу осврће се на Јунгову теорију о анимусу и аними; У области филозофије- на хуманистичку филозофију Ериха Фрома и Ничеове идеје; Социолошка грађа обухвата ауторе од Симон де Бовоар, до Розалинд Мајерс; Религијски аспект анализира и пореди све велике монотеистичке религије и њихов однос према жени, са акцентом на хришћанству, док се астролошки аспект бави утицајем алтернативних наука и езотерије. Практични део истраживања подељен је на четири фазе – развојну, припремну, фазу постављања представе и постпродукцију, а кроз ове фазе је описан целокупан процес настајања позоришне представе.", "The artistic project \"Bed for Three\", realized in the form of a theater play, deals with the critique of the patriarchal system, the position of women, the issue of marriage and family today. Inspired by the play of the same name by Milorad Pavić, the author in this paper also refers to Pavić's literature, hypertext and ergodic literature. The idea of hypertext is associated with hyperdrama and interactive theater. The play \"Bed for Three\" was realized in the spirit of interactivity and refers to the practices of interactive theater in the 20th and 21st century. The topic of the project is treated theoretically from several aspects - psychological, philosophical, sociological, religious-mythological and astrological. In the psychological approach, it refers at Jung's theory of animus and anime; In the field of philosophy - the humanistic philosophy of Erich Fromm and Nietzsche's idea; Sociological material includes authors from Simon de Beauvoir to Rosalind Myers; The religious aspect analyzes and compares all the great monotheistic religions, with an emphasis on Christianity, while the astrological aspect deals with the influence of alternative sciences and esoterics. The practical part of the research is divided into four phases - developmental, preparatory, production and post-production, and through these phases is described the entire process of creating a theatrical play." ]
Универзитет уметности у Београду, Интердисциплинарне студије Универзитета уметности
[ "" ]
[ "openAccess" ]
[ "" ]
Универзитет уметности у Београду
[ "" ]
[ "Милорад Павић", "Milorad Pavić", "Bed for three", "Adam", "Eva", "Lilith hypertext", "hyperdrama", "interactive theater", "animus and anima", "male-female principle", "feminism", "Кревет за троје", "Адам", "Ева", "Лилит хипертекст", "хипердрама", "интерактивно позориште", "анимус и анима", "мушко-женски принцип", "феминизам" ]
[ "КРЕВЕТ ЗА ТРОЈЕ Интерактивна позоришна представа по мотивима истоимене драме Милорада Павића" ]
[ "" ]
other
[ "" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/157629/Disertacija.pdf", "http://nardus.mpn.gov.rs/bitstream/id/157630/Izvestaj.pdf" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_20602" ]
sc
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[ "" ]
[ "" ]
[ "" ]
[ "" ]
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[ "" ]
[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/20610
123456789-20610.pdf
yes
no
http://nardus.mpn.gov.rs/bitstream/id/157643/Disertacija.pdf
no
Осврт: Метаморфоза индивидуалног и колективног сећања - изложба слика
[ "Лађушић, Марко Р." ]
[ "Грубанов, Иван Ј.", "Здравковић, Драган Б.", "Кнежевић, Радомир", "Оташевић, Бојан" ]
Мицић Марјановић, Анђела Љ.
2022-09-06T10:31:35
[ "2022-09-06T10:31:35" ]
2022-04-12
[ "http://eteze.arts.bg.ac.rs/handle/123456789/544", "https://nardus.mpn.gov.rs/handle/123456789/20610" ]
[ "" ]
[ ",,Не постоји боље место од успомена.” – Иво Андрић Проучавајући време, његову промену и кретање, нарочито прошлост као битну компоненту за друштво и појединца, желела сам да уметника и његово стваралаштво укључим као битног чиниоца. Уметник као неизбежни учесник, кроз своја дела, репрезентује нам промене, бележи и чува чињенице прошлости. Такође, истражујући сећања, неизбежно је поменути колективно и индивидуално памћење, наметнута и лажна сећања. Памћење склапа различите садржаје прошлости у смислену целину, селективно чувајући једне а заборављајући друге информације. На тај начин градимо свој лични идентитет и поглед на свет. Прошлост је неминовно осуђена на промене под утицајем друштва, политике, личних ставова, али и неизбежно под сталним утицајем заборава. Предмет уметничког докторског пројекта је истраживање процеса транспоновања постојећих историјских фрагмента и њихова модификација у одређену ликовну целину, цртеж или слику. Сам пројекат представља вид метаморфозе одређеног историјског чина, обрађен кроз ретроспективну анализу. Сећање као тема, неизоставно намеће емоционални доживљај фотографије јер је она коришћена као трансфер успомена. Битан сегмент у овом истраживању, преиспитивању, јесте улога емоционалног памћења. Осим бављења визуелним карактеристикама, анализа радова заснива се и на њиховом разматрању у односу на друштвено-политички, историјски, социјални концепт. Кроз ликовне елементе, аутор податке до којих је дошао обрађује више пута кроз различите ликовне технике, осврћући се на исту сцену више пута градећи њену метаморфозу, желећи да истражи формате свести и подсвести, сећања и заборава и на који начин уметник кроз своје дело може допринети томе. Истраживање је рађено како на сопственом примеру тако и на примеру данас активних уметника. Кроз изложбу слика представићу принцип на који начин је кроз рад функционисало моје сећање, и у ком смеру се оно мењало." ]
Универзитет уметности у Београду, Факултет примењених уметности
[ "" ]
[ "openAccess" ]
[ "" ]
Универзитет уметности у Београду
[ "" ]
[ "Култура сећања", "индивидуално сећање", "колективно сећање", "историјско памћење", "успомене", "реконструисане успомене", "лажна меморија", "фотографија", "метаморфоза." ]
[ "Осврт: Метаморфоза индивидуалног и колективног сећања - изложба слика" ]
[ "" ]
other
[ "" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/157643/Disertacija.pdf" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_20610" ]
sc
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/20607
123456789-20607.pdf
yes
no
http://nardus.mpn.gov.rs/bitstream/id/157638/Disertacija.pdf
no
Непотрепштине-Реконтекстуализација у уметности текстила
[ "Нинчић, Оливера, С." ]
[ "Вељовић, Ивана, Д.", "Огњановић, Мирко, В.", "Чпајак, Горан, Ж.", "Антонијевић, Радош" ]
Цветковић, Златко, М.
2022-09-06T10:31:33
[ "2022-09-06T10:31:33" ]
2022-03-08
[ "http://eteze.arts.bg.ac.rs/handle/123456789/537", "https://nardus.mpn.gov.rs/handle/123456789/20607" ]
[ "" ]
[ "Докторски уметнички пројекат „Непотрепштине – Реконтекстуализација у уметности текстила” се бави укључивањем обичних предмета, у власништву аутора, као грађе за савремену уметничку продукцију у медију текстила. Истраживање представља дефинисање и детекцију специфичне групе ствари из личног окружења, које једном речју називам непотрепштине, као потентног уметничког материјала за развијање нових наратива на бази личног искуства. Процес трансформације свакодневних артефаката из сфере приватног спроводи се реконтекстуализацијом у уметничку, контекстну, креацију која је у домену јавног. Непотрепштине су ситнице - ствари из нашег дома које немају утилитарност и чувамо их из различитих разлога, најчешће сентименталних. То су опредмећени мемоари, иницијатори и окидачи генерисања наших сећања, симболи личног искуства и персоналности. Као такви, у контексту уметности, постају део колективног памћења и идентитета. Сентимент којим одишу ове џиџабиџе нам омогућава да оваква грађа добро кореспондира са емоционалним и концептуалним дискурсом. Историјско-теоријски оквир за пројекат је успостављен елаборацијом значаја контекста, посебно реконтекстуализације, у локалном и глобалном систему уметности. Анализирани су и значајни модалитети контекстуализације: апропријација, деестетизација и понављање. Апострофирана су три главна облика овог процеса која су значајна за уметност текстила, реконтекстуализација текстилних карактеристика, техника-технологија и материјала. Кроз релевантну литературу и личну опсервацију се успоставља однос уметности и предмета, као и предмета и непотрепштина. Завршна поглавља посвећена су анализи реализованих радова у оквиру пројекта и дефинисању закључака." ]
Универзитет уметности у Београду, Факултет примењених уметности
[ "" ]
[ "openAccess" ]
[ "" ]
Универзитет уметности у Београду
[ "" ]
[ "непотрепштине", "предмети", "сентимент", "реконтекстуализација", "контекст", "уметност" ]
[ "Непотрепштине-Реконтекстуализација у уметности текстила" ]
[ "" ]
other
[ "" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/157639/Izvestaj.pdf", "http://nardus.mpn.gov.rs/bitstream/id/157638/Disertacija.pdf" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_20607" ]
sc
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[ "" ]
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https://nardus.mpn.gov.rs/handle/123456789/20611
123456789-20611.pdf
yes
no
http://nardus.mpn.gov.rs/bitstream/id/157644/Disertacija.pdf
no
Форме обликовног система као уточишта драгоценог сећања - скулпторално-мултимедијска целина
[ "Чпајак, Горан Ж." ]
[ "Протић, Јулијана М.", "Кајтез, Слободан Б.", "Денић, Десимир Ж.", "Млађовић, Миодраг" ]
Нићифоровић, Марина И.
2022-09-06T10:31:36
[ "2022-09-06T10:31:36" ]
2022-05-19
[ "http://eteze.arts.bg.ac.rs/handle/123456789/545", "https://nardus.mpn.gov.rs/handle/123456789/20611" ]
[ "" ]
[ "Враћајући се корак уназад започели смо рад кроз ново оживљавање сећања и уједно започели ново уметничко поглавље које се концентрише према пет кључних аспеката: личном, сећајућем, уметничком, истраживачком, документацијском. Водећи се изворима из периода о којем говоримо, компаративним увидима и претходним истраживањима, у тексту се кроз неколико различитих фаза, историјских и практичних, испитује однос уметника према поетици хабитуса као и према вајарској поетици. Рад указује на сећајуће принципе као уметничке праксе и с тим у вези доноси визуелни закључак - скулпторски ансамбл. Уједно се у раду и закључује да, ако се у скулпторском раду доследно прати свака етапа креативног сећања, од оних првих бледих слика простора детињства које прате тупе тактилне сензације, до врелине осећања која се јављају када нас сећања одвуку да поново стварно газимо по стазама одрастања, скулптор ће с великом поузданошћу и у савременом окружењу наћи и материјал и технику и просторну композицију које ће код посматрача побудити сензацију која ће симболички одговарати оној коју је на уму имао скулптор када је својим радовима настојао да испровоцира реакцију публике. Рад се састоји из четири поглавља и прилога који илуструје развој пројекта. У првом (предмет, хипотезе, методе) се општи значај добре скулпторске форме приказује кроз питање зашто су лична сећања у рукама скулптора пресудна за креативност. Истовремено, текст преиспитује значај и улогу историографије личних сећања кроз стандардно документовање извора (стварних и виртуелних), њихове анализе и обликовног тумачења. Друго поглавље је теоријама уметности на које је истраживање ослоњено, а обухвата и излагање сопственог поетичког модела на примерима који су били пресудни за уобличавање нашег уметничког пројекта а односе се на просторе које памтимо, објекате који су одредили наша сећања као и на процесе који су утицали на наше ликовно сазревање и усвајање језика симболичког изражавања. У трећем поглављу је таматски и хронолошки изложена, према постављеним хипотезама, главнина свих наших истраживања пријављене теме. У том поглављу сабирамо закључке нашег истраживања. Излажемо их у три дела. Најпре у односу на теоријски аспект истраживачких претпоставки, потом кроз напор да јасније издвојимо оно што смо наговестили као сопствену поетику и сажимамо допринос који истраживање даје у односу на главну тезу уметничког рада, то јест на оно што је синергија добре форме и дубоког сећања. На крају следе прилози који илуструју развој уметничког пројекта где су изложени кључни моменти развоја од идеје до скулпторске реализације." ]
Универзитет уметности у Београду, Факултет примењених уметности
[ "" ]
[ "openAccess" ]
[ "" ]
Универзитет уметности у Београду
[ "" ]
[ "скулптура", "сећање", "поетика", "визуелно", "баштина", "простор", "култура памћења", "историографија", "реконструкција" ]
[ "Форме обликовног система као уточишта драгоценог сећања - скулпторално-мултимедијска целина" ]
[ "" ]
other
[ "" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/157644/Disertacija.pdf", "http://nardus.mpn.gov.rs/bitstream/id/157645/Izvestaj.pdf" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_20611" ]
sc
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https://nardus.mpn.gov.rs/handle/123456789/20612
123456789-20612.pdf
yes
no
no
Полихромија у камену – Изложба скулптура
[ "Чпајак, Горан Ж." ]
[ "Протић, Јулијана М.", "Лазовић, Мирослав С.", "Денић, Десимир Ж.", "Млађовић, Миодраг" ]
Каравелић, Татјана В.
2022-09-06T10:31:37
[ "2022-09-06T10:31:37" ]
2022-05-11
[ "http://eteze.arts.bg.ac.rs/handle/123456789/546", "https://nardus.mpn.gov.rs/handle/123456789/20612" ]
[ "" ]
[ "Докторски уметнички пројекат, под називом ,,Полихромија у камену, изложба скулптура“ представља теоријски рад и практичнa скулпторска решења приказаних на две концепцептуално различите изложбене поставке. У овом пројекту, анализиране су опсервације из области теорије и историје уметности и геологије. Симбиозом уметничких и научних дисциплина остварен је скулпторски дискурс који је у складу са основним поставкама рада. Полихромија у преводу грчке речи значи вишебојност, у том смислу, истражени су различити утицаји али развијање исте кроз историју уметности. Преиспитивањем односа боје и форме као и међусобно деловање у скулптури, установљено је да полихромијски садржаји у тродимензионалној форми визуелно доприносе динамичности израза. У скулпторским праксама приметан је један приступ инкорпорирања полихромије али и практичне обраде камена, док се у овом пројекту концепт реализује у обрнутим смеру зарад повратка супротним вредностима. Формулација полихромних скулптура у камену представља организован склоп стена различитих генеза. Стога, у овом докторско-уметничком пројекту, полихромија у скулптури настаје интегрисањем различитих, природних материјала. Рад се темељи на истраживању форме у камену и има за циљ успостављање одређене естетске вредности као и доношење потенцијалних резултата на пољу уметности. Полихромија у скулптури, као полазиште али и резултат овог докторско-уметничког рада, остварена је у контексту реверзибилног тумачења основних модела зарад остваривања специфичног скулпторског израза." ]
Универзитет уметности у Београду, Факултет примењених уметности
[ "" ]
[ "openAccess" ]
[ "" ]
Универзитет уметности у Београду
[ "" ]
[ "полихромија", "боја", "форма", "скулптура", "камен", "минерали", "стене", "геолошки процеси", "реверзибилност." ]
[ "Полихромија у камену – Изложба скулптура" ]
[ "" ]
other
[ "" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/157646/Izvestaj.pdf" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_20612" ]
sc
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[ "" ]
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https://nardus.mpn.gov.rs/handle/123456789/20608
123456789-20608.pdf
yes
no
no
Стилско обликовање у условима строгих функционално-техничких захтева на примеру дизајна такмичарског соларног аутомобила у категорији ‘Крузер’
[ "Нешић, Душан Б." ]
[ "Bočina, Ranko N.", "Блажина, Зоран А.", "Протић, Јулијана М.", "Лончаревић, Катарина П." ]
Луковић, Марко М.
2022-09-06T10:31:33
[ "2022-09-06T10:31:33" ]
2022-03-31
[ "http://eteze.arts.bg.ac.rs/handle/123456789/540", "https://nardus.mpn.gov.rs/handle/123456789/20608" ]
[ "" ]
[ "Ovaj doktorski umetnički projekat posvećen je mom kreiranju optimalnog stilskog oblika za eksterijer i elemente enterijera takmičarskog solarnog automobila u kategoriji Cruiser koji je nastao u realizaciji projekta Emilia 4 u Bolonji (Italija), uz uvažavanje strogih funkcionalnotehničkih zahteva iz pravilnika takmičenja (trke) solarnih automobila World Solar Challenge 2015 (Australija). Projekat je realizovao multidisciplinarni tim udruženja Onda Solare povezan sa Univerzitetom u Bolonji. Ja sam kao dizajner uključen u rad tog tima u svojstvu stipendiste doktorskih studija (2015/2016) na Univerzitetu u Bolonji, a na osnovu svojih prethodnih rezultata u realizaciji projekata dizajniranja različitih tipova vozila. Prikazani su svi elementi, faze i tehnike mog rada na kreiranju dizajna solarnog automobila u kategoriji Cruiser, uz korišćenje kompjuterskih 3D CAD-CAM softvera i eksperimentalno proveravanje svih aerodinamičnih performansi kroz CFD (Computer Fluid Dinamics) analize. Moje finalno dizajnersko rešenje prihvaćeno je i korišćeno u konačnoj izradi solarnog automobila Emilia 4, koje je pobedničkim učešćem na takmičenju solarnih automobila American Solar Challenge u kategoriji Cruiser (SAD, 2018) potvrdilo svoje kvalitete. Posle iskustva u radu na projektu Emilia 4 i na osnovu mog celokupnog dvadesetogodišnjeg iskustva u dizajniranju različitih tipova vozila, uz uvažavanje aktuelnih tedencija u savremenoj automobilskoj industriji — na kraju definišem koncept dizajna električnog automobila za opštu upotrebu u drumskom saobraćaju (koji bi se napajao energijom iz elektromreže), uz implementaciju solarnih panela kao sredstva dodatnog izvora električne energije. Preciznije, moja ideja je bila da osmislim dizajn električnog automobila koji bi vizuelno pripadao kategoriji kupe-limuzina (fast-back) za četiri putnika, uz dodatnu inspiraciju oblikom muscle-car automobila. Tako osmišljen dizajn predstavljao bi model futurističkog automobila sa izrazitim aerodinamičnim i sportskim karakteristikama." ]
Универзитет уметности у Београду, Факултет примењених уметности
[ "" ]
[ "openAccess" ]
[ "" ]
Универзитет уметности у Београду
[ "" ]
[ "solarni automobil Cruiser", "Emilia 4", "aerodinamika", "dizajn-proces", "3D CAD-CAM", "CFD analize", "konceptulani dizajn", "električni automobil,fast-back", "muscle-car" ]
[ "Стилско обликовање у условима строгих функционално-техничких захтева на примеру дизајна такмичарског соларног аутомобила у категорији ‘Крузер’" ]
[ "" ]
other
[ "" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/157640/Izvestaj.pdf" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_20608" ]
sc
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
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[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/20631
123456789-20631.pdf
yes
no
https://fedorabg.bg.ac.rs/fedora/get/o:26332/bdef:Content/download
no
Винил и имино деривати пиридина: синтеза, физичко-хемијска карактеризација, биолошка активност и теоријске студије електронске структуре
Vinyl and imino derivatives of pyridine: synthesis, physico-chemical characterization, biological activity, and theoretical studies of electronic structure
[ "Prlainović, Nevena" ]
[ "Cvijetić, Ilija", "Marinković, Aleksandar D.", "Mijin, Dušan", "Bjelogrlić, Snežana" ]
Milošević, Milena D.
2022-09-06T14:03:10
[ "2022-09-06T14:03:10" ]
2021-09-29
[ "https://uvidok.rcub.bg.ac.rs/bitstream/handle/123456789/4427/Referat.pdf", "https://eteze.bg.ac.rs/application/showtheses?thesesId=8745", "https://fedorabg.bg.ac.rs/fedora/get/o:26332/bdef:Content/download", "https://plus.cobiss.net/cobiss/sr/sr/bib/70909449", "https://nardus.mpn.gov.rs/handle/123456789/20631" ]
[ "Предмет истраживања ове докторске дисертације је синтеза, структурна карактеризација винил и имино деривата пиридина и испитивање њихове потенцијалне биолошке активности. Синтетисане су три серије једињења: 1. симетрични 1-метил-2,6-(bis)[2-(супституисани фенил)етенил]пиридинијум-јодиди (bis(винил)пиридинијум-јодиди – БВПЈ) 2. симетрични N,N'-(пиридин-2,6-диил)bis[1-(супституисани фенил)]метанимини (bis(имино)пиридини – БИП) 3. асиметрични дихидразони тиокарбохидразида (дТКХ)..." ]
[ "The main topic of this doctoral dissertation is the synthesis, structural characterization, and examination of potential biological activities of vinyl and imino derivatives of pyridine. Three series of compounds were synthesized: 1. Symmetric 1-methyl-2,6-(bis)[2-(substituted phenyl)ethenyl]pyridinium iodide (bis(vinyl) pyridinium-iodide – БВПЈ) 2. Symmetric N,N'-(pyridine-2,6-diyl)bis[1-(substituted phenyl)]methanimines (bis(imino)pyridines – БИП) 3. asymmetric thiocarbohydrazide dihydrazones (дТКХ)..." ]
application/pdf
sr
Универзитет у Београду, Технолошко-металуршки факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Београду
[ "Винил деривати пиридина", "Имино деривати пиридина", "DFT студије", "LSER анализа", "Антиоксидативна активност", "Антимикробна активност", "Антиканцер активност", "Антикорозивни потенцијал." ]
[ "Vinyl derivatives of pyridine", "Imino derivatives of pyridine", "DFT studies", "LSER analysis", "Antioxidant activity", "Antimicrobial activity", "Anticancer activity", "Anticorrosion potential" ]
[ "Винил и имино деривати пиридина: синтеза, физичко-хемијска карактеризација, биолошка активност и теоријске студије електронске структуре" ]
[ "Vinyl and imino derivatives of pyridine: synthesis, physico-chemical characterization, biological activity, and theoretical studies of electronic structure" ]
doctoralThesis
[ "BY-NC-ND" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/145480/Disertacija_12450.pdf", "http://nardus.mpn.gov.rs/bitstream/id/145481/Izvestaj_Komisije_12450.pdf", "https://fedorabg.bg.ac.rs/fedora/get/o:26332/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_20631" ]
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[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/20628
123456789-20628.pdf
yes
no
https://fedorabg.bg.ac.rs/fedora/get/o:26313/bdef:Content/download
no
Zagađenje površinskog sedimenta Bokokotorskog zaliva teškim metalima i radionuklidima i procena ruzika usled njihove biodostupnosti
Pollution and risk assessment of the surface sediment of the Boka Kotorska Bay with heavy metals and radionuclides due to their bioavailability
[ "Onjia, Antonije" ]
[ "Perić-Grujić, Aleksandra", "Janićijević, Aco", "Pezo, Lato", "Vasić, Milica" ]
Radomirović, Milena
2022-09-06T14:03:05
[ "2022-09-06T14:03:05" ]
2021-11-09
[ "https://eteze.bg.ac.rs/application/showtheses?thesesId=8733", "https://fedorabg.bg.ac.rs/fedora/get/o:26313/bdef:Content/download", "https://plus.cobiss.net/cobiss/sr/sr/bib/70958857", "https://nardus.mpn.gov.rs/handle/123456789/20628" ]
[ "Površinski morski sediment uzorkovan u decembru 2019. godine na dvanaest lokacija u Bokokotorskom zalivu, analiziran je primenom različitih instrumentalnih metoda u cilju postizanja hemijske, teksturalne i radiološke karakterizacije sedimenta. Određen je sadržaj deset oksida i dvadeset šest elemenata (Al2O3, CaO, Fe2O3, K2O, MgO, MnO, Na2O, P2O5, SiO2, TiO2, i As, Ba, Br, Cl, Co, Cr, Cs, Cu, Ga, La, Mo, Nb, Ni, Pb, Rb, S, Sb, Se, Sn, Sr, Th, U, V, Y, Zn, Zr), dodatnih teških metala (Cd, Hg), radionuklida (40K, 226Ra, 232Th, 238U, 137Cs) i njihova prostorna raspodela u zalivu. Pre instrumentalnih analiza, određene su fizičko-hemijske katakteristike sedimenta, poput granulometrijskog sastava, sadržaja organske materije i karbonata. U okviru doktorske disertacije, jedan deo istraživanja odnosio se na procenu ekološkog i radiološkog rizika za period 2019. godine. Za procenu ekološkog statusa sedimenta primenjeni su individualni indeksi, poput faktora obogaćenja (EF), geoakumulacionog indeksa (Igeo), faktora kontaminacije (Cf), zatim i kompleksni indeks, kao što je indeks opterećenja zagađenjem (PLI); koji su se zasnivali na vrednostima potencijalno toksičnih elemenata (Al, Fe, Mn, Cr, Zn, Ni, Cu, Pb, As, Co, U). Primenom individualnih indeksa zagađenja (EF, Cf, Igeo), okriveno je umereno i umereno-do-jako zagađenje u Tivatskom zalivu za većinu teških metala (Ni, Cr, Zn, Cu, As i Pb), što je ukazalo na očigledan uticaj antropogenih aktivnosti koji je doprineo kontaminaciji sedimenta. Primenom PLI, utvrđen je ukupan obim opterećenja teških metala za svaku lokaciju, čime je ukazano na visok nivo zagađenja na lokaciji Bijela brodogradilište. Metode multivarijacione statističke analize istakle su sličnosti odnosno razlike u distribuciji pojedinih ispitivanih elemenata u skladu sa njihovm poreklom. Da bi se obezbedila radiološka procena rizika morskih sedimenata u 2019. godini, najpre je izvršena analiza sadržaja prirodnih radionuklida (40K, 226Ra, 232Th, 238U) i tehnogenog cezijuma (137Cs). Primenjeno je nekoliko dobro utvrđenih parametara (doza zračenja i indeksa), i to spoljašnjih hazard indeksa: ekvivalent aktivnosti radijuma (Raeq), ukupna apsorbovana doza (D), eksterni hazard indeks (Hex), rizik od nastanka kancera tokom života (ELCR); i unutrašnjih hazard indeksa: interni hazard indeks (Hin), godišnja efektivna doza (AEDE), godišnji ekvivalent gonadne doze (AGDE), i indeks iskorišćenja aktivnosti (AUI). Rezultati dobijenih indeksa ukazuju na to da je rizik usled gama zračenja u ispitivanom području u okviru prihvatljivog nivoa. Mape prostorne raspodele radionuklida upućivale su na izraženiju primordijalnu radioaktivnost u unutrašnjem delu zaliva. Korelaciona i klasterska analiza otkrile su snažnu povezanost između primordijalnih radionuklida i većine makroelemenata i napravile jasnu razliku između 226Ra, 232Th, 238U i 137Cs. Drugi deo ovog istraživanja predstavljao je sveobuhvatnu procenu statusa kvaliteta sedimenta, odnosno procenu potencijalne kontaminacije sedimenta. Evaluacija sedimenta izvršena je uporednom analizom vrednosti razmatranih pokazatelja ekološkog rizika i indeksa zagađenja, praćenih na četrdeset lokacija u Bokokotorskom zalivu u različitim sezonama u periodu od 2005. do 2019. godine. U cilju procene potencijalnog ekološkog rizika, ekotoksičnosti sedimenta, identifikacije nivoa toksičnosti i ukupnog opterećenja kontaminacije razmatranih teških metala (As, Cd, Cr, Cu, Hg, Mn, Ni, Pb, Zn, Fe), primenjeni su indeksi poput indeksa opterećenja zagađenjem (PLI), indeksa potencijalnog ekološkog rizika (RI), prosečnog ERM kvocijenta (MERMQ), indeksa toksičnog rizika (TRI) i indeksa jačine kontaminacije (CSI). Nekoliko žarišta u zalivu vizuelno su predstavljena prostornom distribucijom ovih indeksa zagađenja, ukazujući da je sediment u Tivatskom zalivu bio najzagađeniji u okviru ispitivanog područja. Utvrđen je prosečni doprinos pojedinih metala u ukupnom riziku, predstavljen sledećim redosledom: Cd > Hg > As > Pb > Ni > Cu > Cr > Zn. S obzirom na najveći doprinos ukupnom riziku, prisustvo Cd predstavlja prioritet usled toksičnosti koji izaziva veliku zabrinutost u okviru ekosistema zaliva. Na osnovu rezultata, postoji opadajući trend vrednosti sadržaja Hg zabeležen u periodu od 2005. do 2019. godine. Na osnovu rezultata dobijenih indeksima zagađenja ukazano je na Tivatski zaliv kao najzagađeniji deo ispitivanog područja, kako za 2019. godinu, tako i za istraživani period od 2005. do 2019., što je potvrđeno i metodama multivarijacione analize. Multivarijacione statističke metode podržale su primenu smanjenog broja kompleksnih indeksa, s obzirom da je većina njih upućivala na relativno slične zaključke u proceni rizika." ]
[ "Marine surface sediment sampled in December 2019 at twelve locations in the Boka Kotorska Bay was analyzed using different instrumental methods to achieve chemical, textural and radiological characterization of sediment. The content was determined for ten oxides and twenty-six elements (Al2O3, CaO, Fe2O3, K2O, MgO, MnO, Na2O, P2O5, SiO2, TiO2, As, Ba, Br, Cl, Co, Cr, Cs, Cu, Ga, La, Mo, Nb, Ni, Pb, Rb, S, Sb, Se, Sn, Sr, Th, U, V, Y, Zn, Zr), heavy metals (Cd, Hg), radionuclides (40K, 226Ra, 232Th, 238U, 137Cs) was determined, as well as their spatial distribution in the Bay. Before instrumental analysis, physico-chemical characteristics of the sediment were determined, such as granulometric composition, organic matter content and carbonate content. Within the doctoral dissertation, one part of the research referred to the assessment of environmental and radiological risk for the period 2019. Individual indices, such as enrichment factor (EF), geoaccumulation index (Igeo), contamination factor (Cf); and complex index, such as pollution load index (PLI), were applied to assess the ecological status of the sediment, which were based on the values of potentially toxic elements (Al, Fe, Mn, Cr, Zn, Ni, Cu, Pb, As, Co, U). Moderate and moderate-to-strong pollution has been identified in the Tivat Bay for most heavy metals (Ni, Cr, Zn, Cu, As and Pb) using the individual pollution indices EF, Cf and Igeo, which indicated the obvious impact of anthropogenic activities that contributed to sediment contamination. Combining the number of analyzed heavy metals, PLI determined the total heavy metal load for each site, indicating a high level of pollution at the site Bijela shipyard. The multivariate statistical analysis highlighted the similarities and differences in the distribution of individual examined elements in the Bay by their origin. To provide a radiological risk assessment of marine sediments in 2019, the sediment has been first analyzed for the content of natural, primordial radionuclides (40K, 226Ra, 232Th, 238U) and technogenic cesium (137Cs). Several well-established parameters (radiation doses and indices) were applied, such as, external hazard indices: radium equivalent activities (Raeq), absorbed dose rate (D), external hazard index (Hex), excess lifetime cancer risk (ELCR); and internal hazard indices: internal hazard index (Hin), annual effective dose rate (AEDE), annual gonadal dose equivalent (AGDE), activity utilization index (AUI). The results of the obtained indices suggest that the risk due to gamma radiation in the investigated area is within an acceptable level. Spatial distribution maps of radionuclides indicated that primordial radioactivity was more concentrated in the inner part of the Bay. Correlation and cluster analysis revealed a strong association between primordial radionuclides and most macroelements and a clear difference between 226Ra, 232Th, 238U and 137Cs. The second part of this research was a comprehensive assessment of the sediment quality status, that is, an assessment of potential sediment contamination. The sediment evaluation was performed by a comparative analysis of the values of the considered environmental risk indicators and pollution indices, monitored at forty locations in the Boka Kotorska Bay in different seasons in the period from 2005 to 2019. To assess the potential environmental risk, sediment ecotoxicity, identification of toxicity levels and total contamination load of the considered heavy metals (As, Cd, Cr, Cu, Hg, Mn, Ni, Pb, Zn, Fe), indices such as Pollution Load Index (PLI), Potential Ecological Risk Index (RI), Mean ERM Quotient (MERMQ), Toxic Risk Index (TRI), and Pollution Contamination Index (CSI) were applied. Several hotspots in the Bay were visually represented by the spatial distribution of these pollution indices, indicating that the sediment in Tivat Bay was the most polluted within the study area. The average contribution of individual metals in the total risk was determined, presented in the following order: Cd > Hg > As > Pb > Ni > Cu > Cr > Zn. Considering the highest contribution to the overall risk, the presence of Cd is a priority due to the toxicity that causes great concern within the ecosystem of the Bay. Based on the results, there is a declining trend of Hg content observed in the period from 2005 to 2019. Based on the results obtained by pollution indices, the bay of Tivat was the most polluted part of the investigated area, both in 2019 and in the period from 2005 to 2019, which was confirmed by the methods of multivariate analysis. Multivariate statistical methods supported the application of a reduced number of complex indices, as most of them pointed to relatively similar conclusions in the risk assessment." ]
application/pdf
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Универзитет у Београду, Технолошко-металуршки факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Београду
[ "Kvalitet morskog sedimenta", "Indeksi zagađenja", "Parametri radiološkog rizika", "Teški metali", "Radioaktivnost", "Multivarijaciona statistička analiza", "Bokokotorski zaliv" ]
[ "Marine sediment quality", "Pollution indices", "Radiological hazard parameters", "Heavy metals", "Radioactivity", "Multivariate statistical analysis", "Boka Kotorska Bay" ]
[ "Zagađenje površinskog sedimenta Bokokotorskog zaliva teškim metalima i radionuklidima i procena ruzika usled njihove biodostupnosti" ]
[ "Pollution and risk assessment of the surface sediment of the Boka Kotorska Bay with heavy metals and radionuclides due to their bioavailability" ]
doctoralThesis
[ "BY-NC-ND" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/145472/Disertacija_12439.pdf", "http://nardus.mpn.gov.rs/bitstream/id/146552/Izvestaj_Radomirovic.pdf", "https://fedorabg.bg.ac.rs/fedora/get/o:26313/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_20628" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
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[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/19102
123456789-19102.pdf
yes
no
https://fedorabg.bg.ac.rs/fedora/get/o:25764/bdef:Content/download
no
Ispitivanje očuvanosti kardiopulmonalne sprege i njene prediktivne uloge u odgovoru na resinhronizacionu terapiju kod bolesnika sa srčanim slabošću
Examination of cardio-respiratory coupling preservation and its predictive role in response to resynchronization therapy in patients with heart failure
[ "Pavlović, Siniša", "Platiša, Mirjana" ]
[ "Milašinović, Goran", "Pekmezović, Tatjana", "Đurić, Dragan" ]
Radovanović, Nikola
2022-05-31T09:23:00
[ "2022-05-31T09:23:00" ]
2022-03-09
[ "https://eteze.bg.ac.rs/application/showtheses?thesesId=8606", "https://fedorabg.bg.ac.rs/fedora/get/o:25764/bdef:Content/download", "https://plus.cobiss.net/cobiss/sr/sr/bib/67269129", "https://nardus.mpn.gov.rs/handle/123456789/19102" ]
[ "njihove promene izazvane resinhronizacionom terapijom kod bolesnika sa srčanom slabošću (SS) i redukovanom ejekcionom frakcijom leve komore (EFLK). Metode: U istraživanje su uključeni bolesnici sa dilatativnom kardiomiopatijom i indikacijom za resinhronizacionu terapiju srčane slabosti (CRT) i/ili ugradnju implantabilnog kardioverter defibrilatora. Ispitanici su tokom istraživanja bili deljeni u podgrupe u odnosu na karakteristike srčanog ritma, a poređenje je vršeno sa grupom zdravih kontrola. Srčani i respiratorni signali su simultano beleženi tokom 20 minuta, i ispitivani različitim linerarnim i nelinearnim metodama analize vremenskih serija. Kod ispitanika kojima je ugrađen CRT, snimanje signala je ponovljeno nakon godinu dana i analiza promene parametara autonomne funkcije je odvojeno rađena u grupi CRT „rispondera“ i „nerispondera“. Rezultati: U istraživanje je uključeno 156 ispitanika. Kod bolesnika sa SS redukovana je respiratorna sinusna aritmija, kao i bidirekciona interakcija srčanog i respiratornog signala. Bolesnici iz HF-VES grupe su imali najregularniji srčani ritam i najveću sinhronizaciju rada srca i disanja. Identifikovali smo odnos kratkodometnog, α1(RR), i dugodometnog, α2(RR), skalirajućeg eksponenta vremenskog niza RR intervala kao parametar na osnovu kojeg je moguće grupisanje bolesnika sa SS nezavisno od do sada korišćenih karakterisitka bolesnika. Parametar koji je preoperativno odvojio buduće CRT „rispondere“ od „nerispondera“ bio je α2(RR). Tokom praćenja, kompleksnost srčanog i respiratornog ritma je rasla kod CRT „rispondera“, kao i α1(RR) koji je na kontrolnom snimanju imao značajno više vrednosti u odnosu na „nerispondere“. Na kontroli se beleži porast respiratornih skalirajućih eksponenata kod svih bolesnika, sa izuzetkom α1(Resp) kod CRT „nerispondera“. Tokom praćenja, kardiopulmonalna sinhronizacija je bila očuvana kod CRT „rispondera“. Zaključak: kardio-respiratorne interakcije su narušene kod bolesnika sa SS i redukovanom EFLK, i zavise od prisustva komorskih odnosno pretkomorskih aritmija. Uspeh resinhronizacione terapije je značajno povezan sa njihovom stabilnošću" ]
[ "Aim: Examine cardio-respiratory interactions, cardiac and respiratory rhythm, and their changes caused by cardiac resynchronization therapy (CRT) in patients with heart failure (HF) and reduced left ventricular ejection fraction (LVEF). Methods: We included patients with dilated cardiomyopathy and an indication for CRT and/or implantable cardioverter defibrillator implantation. During the study, patients were divided into subgroups according to heart rhythm characteristics, and compared with a group of healthy controls. Cardiac and respiratory signals were simultaneously recorded during 20 minutes, and examined by different linear and nonlinear methods of time series analysis. In subjects with implanted CRT, signal recording was repeated after one year, and the analysis of changes in autonomic function parameters was performed separately in the group of CRT responders and non-responders. Results: We included 156 patients. In HF patients, respiratory sinus arrhythmia and bidirectional causal interactions between the respiratory and cardiac signals were reduced. Patients from the HF-VES group had the most regular heart rhythm and the greatest synchronization of cardiac and respiratory function. We identified the ratio of short-term, α1(RR), and long-term, α2(RR), scaling exponent of RR interval series as a parameter capable to differentiate HF patients regardless of previously used patient characteristics. The parameter that preoperatively separated future CRT \"responders\" from \"non-responders\" was α2(RR). During follow-up, the complexity of cardiac and respiratory rhythm increased in CRT responders, as well as α1(RR), which had significantly higher values at the control recording compared to non-responders. Control measurements showed an increase in respiratory scaling exponents in all patients, with the exception of α1(Resp) in CRT non-responders. During follow-up, cardiopulmonary synchronization was preserved in CRT responders. Conclusion: Cardio-respiratory coupling is altered in HF patients with reduced LVEF and depends on the presence of atrial and ventricular arrhythmias. CRT success is related to cardio-respiratory coupling stability." ]
application/pdf
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Универзитет у Београду, Медицински факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Београду
[ "srčani ritam", "respiratorni ritam", "kardio-respiratorna interakcija", "srčana slabost", "autonomni nervni sistem", "resinhronizaciona terapija", "„risponderi“", "„nerisponderi“", "entropija", "skalirajući eksponenti" ]
[ "heart rhythm", "respiratory rhythm", "cardio-respiratory coupling", "heart failure", "autonomic nervous system", "resynchronization therapy", "responders", "non-responders", "entropy", "scaling exponents" ]
[ "Ispitivanje očuvanosti kardiopulmonalne sprege i njene prediktivne uloge u odgovoru na resinhronizacionu terapiju kod bolesnika sa srčanim slabošću" ]
[ "Examination of cardio-respiratory coupling preservation and its predictive role in response to resynchronization therapy in patients with heart failure" ]
doctoralThesis
[ "BY-NC-ND" ]
Павловић, Синиша; Ђурић, Драган; Платиша, Мирјана; Пекмезовић, Татјана; Милашиновић, Горан; Радовановић, Никола; Испитивање очуваности кардиопулмоналне спреге и њене предиктивне улоге у одговору на ресинхронизациону терапију код болесника са срчаним слабошћу; Испитивање очуваности кардиопулмоналне спреге и њене предиктивне улоге у одговору на ресинхронизациону терапију код болесника са срчаним слабошћу;
[ "http://nardus.mpn.gov.rs/bitstream/id/143347/Disertacija_12297.pdf", "http://nardus.mpn.gov.rs/bitstream/id/143348/Referat_Radovanovic.pdf", "https://fedorabg.bg.ac.rs/fedora/get/o:25764/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_19102" ]
[ "" ]
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https://nardus.mpn.gov.rs/handle/123456789/20711
123456789-20711.pdf
yes
no
https://fedorakg.kg.ac.rs/fedora/get/o:1502/bdef:Content/download
no
Efikasnot rastvora jona srebra na promene oksido - nitrozativnih parametara u terapiji bolesnika sa hroničnim oblikom parodontopatije
Effect of colloidal solution silver ions on the values of oxidative and nitrosative status parameters in the treatment of chronic periodontitis
[ "Lazić, Zoran" ]
[ "Živković, Vladimir", "Lukić, Aleksandra", "Daković, Dragana" ]
Kovačević, Vladan
2022-10-05T20:53:38
[ "2022-10-05T20:53:38" ]
2021-10-06
[ "http://eteze.kg.ac.rs/application/showtheses?thesesId=8551", "https://fedorakg.kg.ac.rs/fedora/get/o:1502/bdef:Content/download", "https://nardus.mpn.gov.rs/handle/123456789/20711" ]
[ "Cilj ovog istraživanja bio je ispitivanje uticaja vodenog rastvora jona srebra (JS) kao lokalnog adjuvantnog antiseptika u okviru kauzalne terapije parodontopatije u poređenju sa rastvorom hlorheksidina (CHX). U istraživanju je praćen uticaj vodenog rastvora jona srebra na vrednosti parametara oksidativnog i nitrozativnog statusa u salivi i gingivalnoj crevikularnoj tečnosti (GCF), kao što su: koncentracija supstanci koje reaguju sa tiobarbiturnom kiselinom (TBARS), koncentracija nitrita i nitrata (NO2+NO3), stvaranje superoksidnog anjona (O2 .- ), određivanje ukupnog antioksidativnog kapaciteta (TAS), aktivnost ukupne superoksid dizmutaze (tSOD), katalaze (SAT), glutation peroksidaze (GPx) i sadržaj ukupnog glutationa (tGSH). U prospektivnoj kohortnoj studiji uzelo je učešće 90 ispitanika (50 bolesnika i 40 kontrolnih subjekata), oba pola, dobi od 25-65 godina, podeljenih u četiri grupe. Prvu grupu (BJS, n=25) činili su ispitanici oboleli od generalizovane hronične parodontopatije, koji su bili tretirani u okviru kauzalne terapije višeseansnom metodom kiretaže parodontalnih džepova i poliranjem površine korena zuba, uz ispiranje parodontalnih džepova vodenim rastvorom jona srebra koncentracije 5mg/ml (JS). Ova grupa je bila praćena pre (BJS pre) i posle (BJS posle) terapije ovim antiseptikom. Druga grupa ispitanika (BCHX, n=25) je pored obrade parodontalnih džepova bila tretirana 0,2% rastvorom hlorheksidina (CHX) i takođe praćena pre (BCHX pre) i posle (BCHX posle) terapije. Kontrolnu grupu činili su sistemski zdravi ispitanici, podeljeni u dve grupe. Jedna grupa je dobijala rastvor jona srebra (ZJS, n=20), a druga rastvor hlorheksidina (ZCHX, n=20) za ispiranje usne duplje. Parametri koji su praćeni odnosili su se na ispitivanje gingive i parodoncijuma (plak ideks, gingivalni indeks, nivo pripojnog epitela, dubina parodontalnog džepa), kao i stepen oksidativnih, odnosno nitrozativnih aktivnosti u salivi i GCF pre i nakon parodontalne terapije. Rezultati sprovedene studije su pokazali da je vodeni rastvor srebrnih jona jednako efikasan kao hlorheksidin, a obzirom na njegovu bolju podnošljivost intezivna primena srebrnih jona kod bolesnika sa hroničnom generalizovanom parodontopatijom pokazuje veliki napredak u terapiji." ]
[ "The aim of this study was to investigate the effect of an colloidal silver ions solution as a local adjuvant antiseptic in the treatment of chronic periodontitis compared with a chlorhexidine solution. The study monitored the effect of an colloidal silver ions solution on the values of oxidative and nitrosative status parameters in saliva and gingival crevicular fluid (GCF), such as: concentration of substances that reacts with thiobarbituric acid (TBARS), concentration of nitrite and nitrate (NO2 +NO3) , superoxide anion formation (O2 .- ), determination of total antioxidant capacity (TAS), total superoxide dismutase (tSOD) activity, catalase (CAT), glutathione peroxidase (GPx) and total glutathione (tGSH) content. The prospective cohort study was encompasseed 90 subjects (50 patients and 40 control subjects), of both sexes, aged 25-65 years, divided into four groups. The first group (BJS, n = 25) consisted of subjects with generalized chronic periodontitis, who were treated with a 5mg/ml of colloidal silver ions solution after scaling and root planing of periodontal pockets. This group was monitored before and after the therapy with this antiseptic. The second group of subjects (BCHX, n = 25) were treated with 0.2% chlorhexidine solution and also monitored before and after the therapy. The control group consisted of systemically healthy subjects, divided into two groups. One group received a colloidal silver ions solution (ZJS, n = 20), and the other a solution of chlorhexidine (ZCHX, n = 20) due to oral cavity rinsing. The monitored parameters related to the examination of the gingiva and periodontium (plaque index, gingival index, the clinical attachment level, the periodontal pocket depth), as well as the degree of oxidative and nitrosative activities in the saliva and GCF before and after periodontal therapy. The results of the study showed that a colloidal silver ions solution was at least equally effective as a chlorhexidine solution. Intensive use of silver ions solution in chronic generalized periodontitis patients showed great progress in causal therapy, because of its better tolerability Key words: periodontitis; oxidative stress; nitrosative status; scaling and root planing; antiseptics" ]
application/pdf
sr
Универзитет у Крагујевцу, Факултет медицинских наука
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-sa/4.0/" ]
Универзитет у Крагујевцу
[ "parodontopatija", "oksidativni stres", "nitrozativni status", "lokalna terapija", "antiseptička sredstva" ]
[ "periodontitis", "oxidative stress", "nitrosative status", "scaling and root planing", "antiseptics" ]
[ "Efikasnot rastvora jona srebra na promene oksido - nitrozativnih parametara u terapiji bolesnika sa hroničnim oblikom parodontopatije" ]
[ "Effect of colloidal solution silver ions on the values of oxidative and nitrosative status parameters in the treatment of chronic periodontitis" ]
doctoralThesis
[ "BY-NC-SA" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/146171/Vladan_Kovacevic_Medicinski.pdf", "http://nardus.mpn.gov.rs/bitstream/id/146172/Doctoral_thesis_12610.pdf", "https://fedorakg.kg.ac.rs/fedora/get/o:1502/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_20711" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
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[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/21411
123456789-21411.pdf
yes
no
https://fedorabg.bg.ac.rs/fedora/get/o:29196/bdef:Content/download
no
Hemometrijski pristup ispitivanju uticaja hemijskih svojstava elektrofilterskog pepela, zeolita i bentonita na svojstva ekološko prihvatljivih građevinskih materijala
Hemometric approach to testing the influence of chemical properties of electrofilter ash, zeolite and bentonite on the properties of ecologically acceptable construction materials
[ "Živojinović, Dragana Z." ]
[ "Terzić, Anja", "Jančić-Heinemann, Radmila", "Perić-Grujić, Aleksandra", "Brčeski, Ilija" ]
Mijatović, Nevenka
2023-05-18T12:55:10
[ "2023-05-18T12:55:10" ]
2022-02-10
[ "https://eteze.bg.ac.rs/application/showtheses?thesesId=9066", "https://fedorabg.bg.ac.rs/fedora/get/o:29196/bdef:Content/download", "https://plus.cobiss.net/cobiss/sr/sr/bib/115395593", "https://nardus.mpn.gov.rs/handle/123456789/21411" ]
[ "Intenzivna industrijalizacija i urbanizacija dovela je do sve veće potrebe za rešenjima koja će doprineti očuvanju životne sredine. Isto se dešava i u oblasti građevinske industrije, gde se čvrst neorganski otpad sve više koristi kao mineralna sirovina u cementoj industriji. U tom smislu nameću se novi izazovi za prilagođavanje hemijskih metoda za analizu sastava višekomponentnih materijala..." ]
[ "Intensive industrialization and urbanization impose increasing needsfor solutions that will contribute to the preservation of the environment. This is also the case in the construction industry, where deposited solid inorganic waste is increasingly used as a mineral raw material in the cement industry. In this sense, new global tendencies are imposed to improve the performance of chemical analysis methods for the analysis of multi-component materials..." ]
application/pdf
sr
Универзитет у Београду, Технолошко-металуршки факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Београду
[ "ICP-OES", "EDXRF", "Mineralni dodaci", "Hemometrija", "Izluživanje" ]
[ "ICP-OES", "EDXRF", "Mineral additives", "Hemometric", "Leaching" ]
[ "Hemometrijski pristup ispitivanju uticaja hemijskih svojstava elektrofilterskog pepela, zeolita i bentonita na svojstva ekološko prihvatljivih građevinskih materijala" ]
[ "Hemometric approach to testing the influence of chemical properties of electrofilter ash, zeolite and bentonite on the properties of ecologically acceptable construction materials" ]
doctoralThesis
[ "BY-NC-ND" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/150874/Disertacija_13506.pdf", "http://nardus.mpn.gov.rs/bitstream/id/152736/Referat.pdf", "https://fedorabg.bg.ac.rs/fedora/get/o:29196/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_21411" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
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[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/21415
123456789-21415.pdf
yes
no
https://fedorabg.bg.ac.rs/fedora/get/o:29285/bdef:Content/download
no
Separacija/stabilizacija odabranih teških metala iz vode i zemljišta primenom otpadnih ljuštura školjki
Separation/stabilization of selected heavy metals from water and soil using waste seashells
[ "Perić-Grujić, Aleksandra" ]
[ "Smičiklas, Ivana", "Ristić, Mirjana", "Jović, Mihajlo" ]
Egerić, Marija
2023-05-18T12:55:16
[ "2023-05-18T12:55:16" ]
2022-02-04
[ "https://eteze.bg.ac.rs/application/showtheses?thesesId=9078", "https://fedorabg.bg.ac.rs/fedora/get/o:29285/bdef:Content/download", "https://plus.cobiss.net/cobiss/sr/sr/bib/115376393", "https://nardus.mpn.gov.rs/handle/123456789/21415" ]
[ "Ubrzani industrijski razvoj doveo je do globalnih problema iscrpljivanja prirodnih resursa, zagađenja životne sredine, generisanja i akumulacije otpada. Ljušture školjki, poreklom iz prehrambene industrije, koje se u milionima tona generišu svake godine, deponuju se u priobalnim područjima gde negativno utiču na celokupnu životnu sredinu. Kao sekundarni izvor kalcijum karbonata, ovaj materijal predstavlja potencijalnu zamenu za prirodni krečnjak, čija je dostupnost ograničena. Otpadne ljušture školjki imaju široku primenu u oblastima kao što su: tretman vode i zemljišta različitog stepena zagađenja, ishrana domaćih životinja, proizvodnja gume, boja, farmaceutskih proizvoda..." ]
[ "Global industrial development has led to the fast depletion of natural resources, environmental pollution, and waste generation and accumulation. The seafood industry generates millions of tons of mollusc shells, which are deposited in coastal areas with negative effects on the entire environment. As a secondary source of calcium carbonate, seashells are a potential substitute for limestone, which availability in nature is limited. Waste seashells are already being applied in different areas, such as wastewater and soil treatment, animal feed production, pharmaceuticals, paint, and rubber production..." ]
application/pdf
sr
Универзитет у Београду, Технолошко-металуршки факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Београду
[ "otpadne ljušture školjki", "teški metali", "kalcijum-karbonat", "sorpcija", "neuronske mreţe", "eksperimentalni dizajn", "remedijacija zemljišta", "biodostupnos" ]
[ "seashell waste", "heavy metals", "calcium-carbonate", "sorption", "wastewater treatment", "neural networks", "experimental design", "soil remediation", "bioavailability" ]
[ "Separacija/stabilizacija odabranih teških metala iz vode i zemljišta primenom otpadnih ljuštura školjki" ]
[ "Separation/stabilization of selected heavy metals from water and soil using waste seashells" ]
doctoralThesis
[ "BY-NC-ND" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/150886/Disertacija_13518.pdf", "http://nardus.mpn.gov.rs/bitstream/id/152738/Referat.pdf", "https://fedorabg.bg.ac.rs/fedora/get/o:29285/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_21415" ]
[ "" ]
[ "" ]
[ "" ]
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[ "" ]
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[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/21491
123456789-21491.pdf
yes
no
http://nardus.mpn.gov.rs/bitstream/id/151243/Disertacija_13609.pdf
no
Uticaj placentalnog hormona rasta i insulinu sličnog faktora rasta 1 na glomerule bubrega miševa rođenih sa intrauterusnom restrikcijom rasta
Effect of Placenta Growth Hormone and Insulin-like Growth Factor 1 on kidney glomeruli of mice born with intrauterine growth restrictions
[ "Stojanović, Vesna" ]
[ "Konstantinidis, Georgios", "Kolarović, Jovanka", "Velisavljev-Filipović, Gordana", "Spasojević, Slobodan", "Andrić, Silvana" ]
Сташук, Наташа
2023-06-14T12:25:53
[ "2023-06-14T12:25:53" ]
2023-05-17
[ "https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija167507919096154.pdf?controlNumber=(BISIS)128229&fileName=167507919096154.pdf&id=21397&source=NaRDuS&language=sr", "https://www.cris.uns.ac.rs/record.jsf?recordId=128229&source=NaRDuS&language=sr", "https://www.cris.uns.ac.rs/DownloadFileServlet/IzvestajKomisije167507919990836.pdf?controlNumber=(BISIS)128229&fileName=167507919990836.pdf&id=21398&source=NaRDuS&language=sr", "https://nardus.mpn.gov.rs/handle/123456789/21491" ]
[ "Neonatusi koji su in utero izloženi aberantnim fetalnim, maternalnim ili placentalnim faktorima koji koče pravilan rast i razvoj fetusa pripadaju visokorizičnoj grupi novorođenčadi sa intrauterusnom restrikcijom rasta (IUGR). Prema konceptu razvojnog programiranja hroničnih bolesti, dugoročne konsekvence IUGR se protežu do odraslog doba. Patofiziološki mehanizmi ovog procesa su višestruki i delimično razjašnjeni, ali se zna da smanjeni broj nefrona na rođenju kod IUGR potomaka izaziva kompenzatornu hipertrofiju glomerula i pokreće patološke mehanizme koji mogu usloviti razvoj hipertenzije i hroničnu bubrežnu insuficijenciju. Cilj studije je da se na eksperimentalnom modelu intrauterusne restrikcije rasta kod miševa ispita da li IUGR utiče na smanjenje broja glomerula miševa, da li davanje placentalnog hormona rasta (PGH) i insulinu sličnog faktora rasta 1 (IGF1) u različitim dozama utiče na povećanje broja i veličine glomerula i da li je bubrežna funkcija miševa sa IUGR, koji su nakon rođenja dobili PGH i IGF1, u adultnoj dobi kada su žrtvovani, bolja u odnosu na one koji nisu dobili PGH i IGF1. Metode: Korišćen je eksperimentalni model IUGR u kome su gravidne ženke dobijale deksametazon u dozi od 100μg/kg/dan supkutano od 15-21. dana gestacije, tj. do dana porođaja. Po metodi slučajnog izbora mladunci su razvrstani u jednu od šest grupa, po deset miševa u svakoj i ostavljeni na prirodnoj ishrani. Žrtvovani su nakon mesec dana. Iz srca se uzelo 0,5ml krvi za analizu koncentracije cistatina C i kreatinina, a potom je kod svake žrtvovane jedinke odstranjen po jedan bubreg. Histološkom obradom su dobijene pločice koje su analizirane uz pomoć digitalnog mikroskopa, skenirane i prevedene u digitalnu formu. Upotrebom softverskih sistema izračunata je numerička gustina i volumen glomerula svake grupe pojedinačno, u sve tri zone kore bubrega. Rezultati: Miševi kod kojih je eksperimentom izazvan IUGR su imali manji broj glomerula u odnosu na kontrolnu grupu (27.700 vs 36.111). U grupi miševa koji su dobili veću dozu IGF1 (10μg) je bio povećan i broj i volumen glomerula, a koncentracija kreatinina najniža u odnosu na osve ostale grupe, sa statistički značajnom razlikom (r<0,033) u odnosu na kontrolnu grupu bez intervencije. Davanje manje doze IGF1 (1μg), kao i davanje manje (2μg) i veće (10μg) doze PGH nije izazvalo povećanje broja i volumena glomerula. Davanje 10μg PGH je dovelo do smanjenog broja glomerula u površinskoj i intermedijarnoj zoni sa statistički značajnom razlikom (r<0,05) u odnosu na grupu koja je dobila 10μg IGF1 i kontrolnu grupu bez intervencije, kao i do smanjenja volumena glomerula sa statistički značajnom razlikom (r<0,05) u odnosu na grupu koja je dobila 10μg IGF1. Analiza cistatina C je slična u svim ispitivanim grupama. Zaključak: Veća doza IGF1 (10μg) povećava numeričku gustinu i volumensku frakciju glomerula, ali su potrebne dugoročne studije i na životinjskim modelima i na humanoj populaciji da utvrde da li će u starosti glomeruloskleroza i posledična hronična bubrežna insuficijencija pre nastupiti kod IUGR potomaka koji nakon rođenja nisu dobili IGF1 u odnosu na one koji su dobili IGF1, tj. da li aplikovanje IGF1 nakon rođenja IUGR potomci ima protektivno dejstvo i može duže da očuva funkciju njihovih bubrega. U dostupnoj literaturi nema podataka o istraživanjima dejstva PGH na glomerule IUGR potomstva, te su potrebna dalja ispitivanja da bi se dobili relevantni podaci o patofiziološkom dejstvu PGH." ]
[ "Objectives:Neonates that were in utero subject to aberrant fetal, maternal or placental factors that retard normal growth and development of the fetus are considered a high-risk group of newborns with intrauterine growth restriction (IUGR). According to the concept of developmental programing of chronic illness, long term consequences of IUGR are present up until adulthood. Pathophysiological mechanisms of this process are manifold and only partially understood, but it is accepted that lowered nephron number at birth in IUGR offspring causes compensatory hypertrophy of glomeruli and initiates pathological mechanisms that can cause the development of hypertension and chronic kidney failure. The aim of the study is to investigate, using an experimental model of intrauterine growth restriction in mice, whether IUGR affects the decrease in the number of glomeruli in mice, whether the administration of placental growth hormone (PGH) and insulin-like growth factor 1 (IGF1) in different doses affects the increase in number and size glomeruli and whether the kidney function of mice with IUGR, which received PGH and IGF1 after birth, in adulthood when they were sacrificed, is better compared to those that did not receive PGH and IGF1. Methods: An experimental model of IUGR was used in which pregnant females received dexamethasone at a dose of 100μg/kg/day subcutaneously from 15-21. days of gestation, i.e. until the day of delivery. According to the method of random selection, the cubs were divided into one of six groups, ten mice in each, and left on natural food. They were sacrificed after a month. 0.5 ml of blood was taken from the heart for analysis of cystatin C and creatinine concentration, and then one kidney was removed from each sacrificed individual. Plates were obtained through histological processing, which were analyzed with the help of a digital microscope, scanned and translated into digital form. Using software systems, the numerical density and volume of the glomeruli of each group was calculated individually, in all three zones of the kidney cortex. Results: Mice with experimentally induced IUGR had a lower number of glomeruli compared to the control group (27,700 vs 36,111). In the group of mice that received a higher dose of IGF1 (10μg), the number and volume of glomeruli increased, and the creatinine concentration was the lowest compared to all other groups, with a statistically significant difference (p<0.033) compared to the control group without intervention. Administration of a lower dose of IGF1 (1 μg), as well as administration of a lower (2 μg) and higher (10 μg) dose of PGH did not cause an increase in the number and volume of glomeruli. The administration of 10 μg of PGH led to a decreased number of glomeruli in the superficial and intermediate zone with a statistically significant difference (p<0.05) compared to the group that received 10 μg of IGF1 and the control group without intervention, as well as to a decrease in the volume of glomeruli with a statistically significant difference (p<0.05) compared to the group that received 10 μg of IGF1. Cystatin C analysis didn’t reveal any differences between studied groups. Conclusion: A higher dose of IGF1 (10 μg) increases the numerical density and volume fraction of glomeruli, but long-term studies in both animal models and human populations are needed to determine whether glomerulosclerosis and subsequent chronic renal failure in old age will occur earlier in IUGR offspring that did not receive after birth IGF1, compared to those who received IGF1, ie. whether applying IGF1 after birth to IUGR offspring has a protective effect and can preserve the function of their kidneys longer. In the available literature, there is no data on research on the effect of PGH on the glomeruli of IUGR offspring, and further studies are needed to obtain relevant data on the pathophysiological effect of PGH." ]
sr (latin script)
Универзитет у Новом Саду, Медицински факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Новом Саду
[ "nefroni", "glomeruli bubrega", "intrauterina restrikcija rasta", "hipertenzija", "hronična bubrežna insuficijencija", "insulinu sličan faktor rasta 1", "hormon rasta", "placentalni hormoni", "kreatinin", "cistatin C", "životinjski modeli", "miševi" ]
[ "Nephrons", "Kidney Glomerulus", "Fetal Growth Retardation", "Hypertension", "Renal Insufficiency, Chronic", "Insulin-Like Growth Factor I", "Growth Hormone", "Placental Hormones", "Creatinine", "Cystatin C", "Models, Animal", "Mice" ]
[ "Uticaj placentalnog hormona rasta i insulinu sličnog faktora rasta 1 na glomerule bubrega miševa rođenih sa intrauterusnom restrikcijom rasta" ]
[ "Effect of Placenta Growth Hormone and Insulin-like Growth Factor 1 on kidney glomeruli of mice born with intrauterine growth restrictions" ]
doctoralThesis
[ "BY-NC-ND" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/151243/Disertacija_13609.pdf", "http://nardus.mpn.gov.rs/bitstream/id/151244/Izvestaj_komisije_13609.pdf", "https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija167507919096154.pdf?controlNumber=(BISIS)128229&fileName=167507919096154.pdf&id=21397&source=NaRDuS&language=sr" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_21491" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
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[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/21428
123456789-21428.pdf
yes
no
https://fedorabg.bg.ac.rs/fedora/get/o:29313/bdef:Content/download
no
Istraživanje antimikrobne aktivnosti i hromatografskog ponašanja sastojaka endofitnih gljiva primenom hemometrijskih metoda
Investigation of antimicrobial activity and chromatographic behavior of endophytic fungi constituents using chemometric methods
[ "Otašević, Biljana" ]
[ "Štrukelj, Borut", "Zečević, Mira", "Protić, Ana", "Filipić, Brankica" ]
Ignjatović, Janko
2023-05-18T12:56:12
[ "2023-05-18T12:56:12" ]
2022-09-29
[ "https://eteze.bg.ac.rs/application/showtheses?thesesId=9083", "https://fedorabg.bg.ac.rs/fedora/get/o:29313/bdef:Content/download", "https://plus.cobiss.net/cobiss/sr/sr/bib/77500937", "https://nardus.mpn.gov.rs/handle/123456789/21428" ]
[ "Rezistencija bakterija na delovanje antibiotika predstavlja globalni problem. Na polju razvoja novih lekova iz prirodnih izvora, nedavno je prepoznat potencijal endofitnih gljiva zahvaljujući sposobnosti da proizvedu sekundarne metabolite različitih bioloških aktivnosti. Biosinteza ovih jedinjenja je pod velikim uticajem brojnih faktora koji se vezuju za izbor biljke domaćina, klimatske uslove, ishranu i prisustvo drugih mikroorganizama u okruženju. Velika baza podataka vezanih za aktivnost endofitnih gljiva prema patogenim bakterijama pretaživana je primenom metode analize glavnih komponenti sa ciljem pronalaženja obrazaca u podacima koji bi ukazali na manji broj pravih kandidata za novih razvoj lekova. Na ovaj način, osvetljen je antimikrobni karakter gljive Phomopsis species. In vitro testovima je potvrđeno da dihlormetanski ekstrakt gljive izolovane iz četina bora inhibira rast bakterija Escherichia coli i Staphylococcus aureus. Hromatografsko razdvajanje pojedinačnih jedinjenja ekstrakta optimizovano je primenom dizajna eksperimenata, a zatim je izvršeno izolovanje i karakterizacija njihove hemijske strukture korišćenjem masene spektrometrije i NMR spektroskopije. In silico metodama su definisani prediktori bioraspoloživosti i toksikološke aktivnosti jedinjenja (Z)-(Z)-2-acetoksiprop-1-en-1-il-3-(3-((E)-3,4-dihidroksipent-1-en-1- il)oksiran-2-il)akrilat i (Z)-(Z)-2-acetoksiprop-1-en-1-il-(3-((E)-4-hidroksi-3-oksopent-1-en-1- il)oksiran-2-il)akrilat. Za razliku od dosadašnih istraživanja koja su se ograničavala in vitro testovima antimikrobne aktivnosti endofitnih gljiva i razrešavanjem hemijske strukture izolovanih biomolekula, ova disertacija predstavlja proširenje prethodnih istraživanja primenom in silico metoda. Studija molekulskog dokinga omogućila je razumevanje mehanizama interakcije biomolekula sa receptorima koji pripadaju patogenim bakterijama uobičajeno multirezistentnim na antibiotike. Primenom veštačkih neuronskih mreža nagrađeni su pouzdani modeli koji ukazuju na vezu između hemijske strukture, parametara interakcije i afiniteta vezivanja za receptore na osnovu kojih je moguć razvoj novih hemijski srodnih antibiotika." ]
[ "Bacterial resistance towards antibiotics represents a global phenomenon. Potential of endophytic fungi as producers of secondary metabolites with wide spectra of different bioactivities in the field of drug discovery from natural resources has recently been introduced. The production of these compounds is under great impact of variety of factors related to the choice of plant host, climate conditions, nutrition and presence of other microorganisms in the same surrounding. Big data set comprising of indices of endophytic fungi antibacterial activity towards patogen bacteria was evaluated using principal component analysis with the aim to find patterns in data and to point out to a limited number of proper candidates for future pharmaceutical research. This resulted in highlightening of the antimicrobial character of Phomopsis species. In vitro tests proved that dichloromethane extract of endophytic fungi isolated from conifer needles inhibits the growth of Escherichia coli and Staphylococcus aureus. Chromatographic separation of individual components of extract was optimized using design of experiments followed by the isolation and chemical structure characterization using mass spectrometry and NMR spectroscopy. In silico methods were used to define the predictors of bioavaliability and toxicological activity of compounds (Z)-(Z)-2-acetoxyprop-1-en-1-yl-3- (3-((E)-3,4-dihydroxypent-1-en-1-yl)oxiran-2-yl)acrylate and (Z)-(Z)-2-acetoxyprop-1-en-1- yl-3-(3-((E)-4-hydroxy-3-oxopent-1-en-1-yl)oxiran-2-yl)acrylate. Unlike up to date research outcomes limited to in vitro evaluation of antimicrobial activity of endophytic fungi and chemical structure elucidation of isolated biomolecules, this disertation represents an extension to previous investigations using in silico methods. The molecular docking study enabled the comprehensive understanding of the mechanisms underlying the interaction of biomolecules with receptors belonging to usually multidrug resistant bacterial pathogens. The artificial neural networks were used to build reliable models relating chemical structure, parameters of interaction and the binding affinity to receptors, thus providing the essence for future development of new chemically related antibiotics." ]
application/pdf
sr
Универзитет у Београду, Фармацеутски факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Београду
[ "Antibakterijska aktivnost", "Endofitne gljive", "Hemometrijske metode u farmaceutskom istraživanju", "in silico razvoj lekova" ]
[ "Antibacterial activity", "Endophytic fungi", "Chemometric methods in pharmaceutical research", "in silico drug discovery" ]
[ "Istraživanje antimikrobne aktivnosti i hromatografskog ponašanja sastojaka endofitnih gljiva primenom hemometrijskih metoda" ]
[ "Investigation of antimicrobial activity and chromatographic behavior of endophytic fungi constituents using chemometric methods" ]
doctoralThesis
[ "BY-NC-ND" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/150925/Disertacija_13523.pdf", "http://nardus.mpn.gov.rs/bitstream/id/152751/Referat.pdf", "https://fedorabg.bg.ac.rs/fedora/get/o:29313/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_21428" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/11144
123456789-11144.pdf
yes
no
https://fedorakg.kg.ac.rs/fedora/get/o:1100/bdef:Content/download
no
Savremena književnost ruskih Nemaca: problem tradicije
Modern Literature of the Russian Germans: the problem of tradition
[ "Bošković, Dragan" ]
[ "Nikolić, Časlav", "Arsenijević Mitrić, Jelena", "Antanasijević, Irina" ]
Šuklin, Aleksandar
2019-05-30T12:15:42
[ "2019-05-30T12:15:42", "2020-07-03T15:24:25" ]
2018-11-26
[ "http://eteze.kg.ac.rs/application/showtheses?thesesId=6673", "https://nardus.mpn.gov.rs/handle/123456789/11144", "https://fedorakg.kg.ac.rs/fedora/get/o:1100/bdef:Content/download" ]
[ "Doktorska teza \"Savremena književnost ruskih Nemaca: problem tradicije\" posvećena je problemu pojma \"tradicije\" u savremenoj književnosti ruskih Nemaca na materijalima dela Olega Klinga (priča \"Stvarni pejzaž\"), Aleksandara Rajzera (priča \"Staro Jevanđelje od Jovana\"), Huga Vormsbehera (priča \"Naše dvorište\"). Svrha detaljne analize ovih radova je potvrđivanje postojeće nacionalne književne tradicije u književnosti ruskih Nemaca. U prvom delu doktorske teze prikazuje se istorija izučavanja pojma \"tradicije\" u književnoj kritici. Analiza ovog pojma pokazuje da nema jasnu i nedvosmislenu interpretaciju u nauci u ovom trenutku. Mnogi naučnici su koristili ovaj koncept tokom XX veka, i nastavljaju da ga koriste početkom XXI veka. Međutim, tumačenje termina svaki put dobija drugačiji karakter i uglavnom se ne poklapa sa stavovima drugih naučnika. To jest, mnogi naučnici posmatraju koncept \"tradicije\" samo kroz kategoriju uzastopnih veza, i tvrde da može da postoji u književnosti samo u prisustvu direktnog kontakta između pisaca (tzv. mentorstvo) ili između pisca i dela njegovih prethodnika. Dakle, otuda i veliki broj radova posvećenih uticaju jednog pisca6 na dela drugog. Često književni kritičari pokušavaju da dokažu da među piscima postoji direktan ili indirektan kontakt. Takođe, u mnogim studijama samo je formalno navedeno postojanje uticaja tradicije na autora određene nacionalne književnosti. U tom slučaju, koncept \"tradicije\" se smatra kao nešto što se podrazumeva, i nije tretiran od strane istraživača, usled čega se gubi svaki smisao takvog istraživanja. Autor teze je predložio precizan pojam: \"nacionalna književna tradicija\", koji se zasniva na kategoriji kulturnog sećanja naroda. Mi ne možemo uvek govoriti (ili dokazati) o postojećem uticaju jednih autora na druge. Na primeru književnosti ruskih Nemaca u radu pokazano je kako istorija književnosti može u potpunosti da se prekine i ponovo oživi. Na taj način se potpuno gubi veza između pisaca. Ali, književna tradicija ponovo i ponovo oživljava. Za proučavanje ovog fenomena u radu koristi se upravo pojam \"nacionalna književna tradicija\". U drugom delu teze detaljno se analiziraju umetnička dela Olega Klinga, Aleksandara Rajzera i Huga Vormsbehera. Autor teze identifikuje i analizira specifične za nacionalnu književnu tradiciju ruskih Nemaca sliku domovine, sliku rodne kuće, sliku majke, motiv religije, motiv maternjeg nemačkog jezika. U trećem delu teze ispituje se književni lik Sibira u delima pisaca - ruskih Nemaca, i sprovodi se detaljna analiza sa stanovišta7 nacionalne književne tradicije. Na osnovu sprovedene analize u tezi zaključuje se da književnost ruskih Nemaca ima svoju nacionalnu književnu tradiciju i da se s punim pravom može svrstati u petu nemačku književnost u svetu." ]
[ "Doctoral thesis \"Modern Literature of the Russian Germans: the problem of tradition\" is dedicated to problematizing the concept of \"tradition\" in the contemporary literature of the Russian Germans on the works of Oleg Kling (story \"Nonfictional landscape\"), Alexander Reiser (story \" The Old Gospel of John \"), Hugo Vormsbehera (the story \"Our yard\"). The purpose of a detailed analysis of these works is to confirm the existing its own national literary tradition in the literature of the Russian Germans. In the first part of the doctoral thesis, the history of the study of the concept of \"tradition\" in literary criticism is examined in detail. Analysis of this concept shows that it does not have a clear and unambiguous interpretation in science at the moment. Many scientists used this concept throughout the XX century and continue to use it at the beginning of the 21st century. However each time the interpretation of this term acquires a different character and largely does not coincide with the opinion of other scientists. In particular many scholars consider the concept of \"tradition\" only through the category of successive links and declare that it can exist9 in literature only if there is direct contact between writers (so-called mentoring) or between a writer and the work of his predecessors. Hence many works devoted to the influence of one writer on the work of another. Every time literary scholars try to prove that there has been fulltime or correspondence contact between writers. Also in many works only formally declared the existence of the influence of tradition on the author of a certain national literature. In this case the concept of \"tradition\" is regarded as a matter of course and is not generally interpreted by the researcher, as a result of which any meaning of such research is lost. The author of the thesis proposed an expanded concept of \"national literary tradition\", based on the categories of cultural memory of the people. We can not always say (or prove) the existing influence of some authors on others. On the example of the literature of the Russian Germans, the work shows how the history of literature can repeatedly be completely interrupted and reborn again. At the same time, contact between writers is completely lost. But the literary tradition re-emerges again and again. For the investigation of this phenomenon, the term \"national literary tradition\" is used in the work. In the second part of the thesis works by Oleg Kling, Alexander Raiser, Hugo Wormsbacher are analyzed in detail. The author of the dissertation has identified and analyzed the image of the homeland, the image of the native home, the image of the mother, the motif of religion, the motive of the native German language which is typical for the Russian literary tradition of Russian Germans. The third part of the thesis examines the literary image of Siberia in the works of writers - Russian Germans and conducts a detailed analysis from the point of view of the national literary tradition. On the basis of the analysis carried out in the dissertation is concluded that the literature of Russian Germans has its own national literary tradition and with full rights is the fifth German literature in the world." ]
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Универзитет у Крагујевцу, Филолошко-уметнички факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Крагујевцу
[ "književna tradicija", "nacionalni identitet", "ruski Nemci", "slika domovine", "slika rodne kuće", "slika majke", "motiv religije", "motiv nemačkog jezika" ]
[ "literary tradition", "national identity", "Russian Germans", "the image of the motherland", "the image of the home", "the image of the mother", "the motif of religion", "the motif of the German language" ]
[ "Savremena književnost ruskih Nemaca: problem tradicije" ]
[ "Modern Literature of the Russian Germans: the problem of tradition" ]
doctoralThesis
[ "BY-NC-ND" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/51023/Disertacija.pdf", "http://nardus.mpn.gov.rs/bitstream/id/51024/Aleksandr_Suklin_FULUM.pdf", "https://nardus.mpn.gov.rs/bitstream/id/51024/Aleksandr_Suklin_FULUM.pdf", "https://nardus.mpn.gov.rs/bitstream/id/51023/Disertacija.pdf", "https://fedorakg.kg.ac.rs/fedora/get/o:1100/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_11144" ]
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https://nardus.mpn.gov.rs/handle/123456789/6897
123456789-6897.pdf
yes
yes
https://fedorakg.kg.ac.rs/fedora/get/o:701/bdef:Content/download
no
Upotreba manipulativa u razvoju matematičkog mišljenja
[ "Popović, Branislav" ]
[ "Vulović, Nenad", "Mihajlović, Aleksandra", "Ikodinović, Nebojša" ]
Damjanović, Radojko
2016-10-29T13:33:19
[ "2016-10-29T13:33:19", "2020-07-03T15:25:05" ]
2016-09-23
[ "http://eteze.kg.ac.rs/application/showtheses?thesesId=4070", "https://nardus.mpn.gov.rs/handle/123456789/6897", "https://fedorakg.kg.ac.rs/fedora/get/o:701/bdef:Content/download" ]
[ "Manipulativi u nastavi matematike predstavljaju svojevrstan agens procesa razvoja matematičkog mišljenja. O ovome svedoče mnogobrojna teorijska i empirijska istraživanja koja su realizaovana u svetu, ali o tome se kod nas (u Srbiji) malo zna ili malo upotrebljava. Disertacija koristi sve najznačajnije, relevantne teorijske i empirijske nalaze iz oblasti upotrebe manipulativa u procesu nastave i učenja i sistematizuje ih, tako da uz empirijsko istraživanje stavova i mišljenja nastavnika o manipulativima, na uzorku u Srbiji daje jedinstvenu celinu. Dragocenost ove disertacije jeste u tome što predstavlja originalan prikaz okolnosti obrazovanja u svetu, filozofske i psihološke postavke pojma mišljenja, kao i alternativnih pristupa (lateralno razmišljanje). Nakon širokog pregleda i uvoda o pojmu mišljenja i konačno matematičkog mišljenja, disertacija se bavi manipulativima kao korisnim alatima nastave i učenja matematike i razvoja matematičkog mišljenja. Stvaranjem dualnih matematičkih reprezentacija, prevođenjem konkretnih okolnosti matematičke strukture u vizuelne reprezentacije, stvara se mentalna slika kojom se operiše na mentalnom planu i tako konkretno prelazi u formalno i apstraktno. Umešnost nastavnika da vodi ove procese u kojima se upotrebljavaju manipulativi, razlike i sličnosti između realnih ili fizičkih i virtuelnih manipulativa jeste jedna od podtema koje se izlažu u ovoj disertaciji. Prilozi za temu upotrebe manipulativa u funkciji razvoja matematičkog mišljenja imaju svrhu u približavanju objašnjenja nekog pojma ili fenomena koji se koristi tokom izlaganja u glavnom delu disertacije i od posebnog je značaja. Mnogi pojmovi su prava retkost/novost u polju metodike nastave matematike kod nas, tako da je u tom smislu ova disertacija od posebne važnosti. Obiman spisak referenci na koje se disertacija poziva, analiziran je i strukturisan i daje se kao prilog ovog rada." ]
[ "Within the process of teaching mathematics manipulatives represent a kind of an agent in the process of developing mathematical thinking. A lot of theoretical and empirical research conducted around the world testifies to this fact, and yet here (in Serbia) this is little known or employed too little. This dissertation uses all the most significant and relevant theoretical and empirical findings from the area of using manipulatives in the process of teaching and learning and systematizes them, providing a unified whole together with the empirical research of the teachers’ attitudes and opinions on manipulatives sampled in Serbia. The value of this dissertation lies in the fact that it gives an original overview of the educational conditions throughout the world, philosophical and psychological bases for the notion of thinking, as well as some alternative approaches (such as lateral thinking). After a broad overview and introduction about the notion of thinking and eventually mathematical thinking, this dissertation deals with manipulatives as useful tools for teaching and learning mathematics and for the development of mathematical thinking. By creating dual mathe-matical representations, translating concrete conditions of a mathematical structure into visual representation, a mental image is formed which is then used on the mental level and in such way concrete is transformed into formal and abstract. The versatility of the teacher to lead these processes in which manipulatives are used as well as differences and similarities between real or physical and virtual manipulatives belong to one of the subthemes developed in this dissertation. These contributions to the theme of using manipulatives in the function of developing mathematical thinking have the purpose to facilitate a closer interpretation of notions or phenomena used within the main part of the dissertation and is of special significance. Some of the notions are true rarities/novelties in the field of methods of teaching mathematics in our country and that is why this dissertation holds special importance. Voluminous list of references cited in this dissertation is analyzed and structured, and given as an addendum to this thesis." ]
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sr
Универзитет у Крагујевцу, Факултет педагошких наука, Јагодина
[ "" ]
[ "openAccess" ]
[ "" ]
Универзитет у Крагујевцу
[ "manipulativi", "mišljenje", "matematičko mišljenje", "razvoj mišljenja", "razvoj matematičkog mišljenja", "fizički manipulativi", "virtuelni manipulativi" ]
[ "manipulatives", "thinking", "mathematical thinking", "the development of thinking", "the development of mathematical thinking", "physical manipulatives", "virtual manipulatives" ]
[ "Upotreba manipulativa u razvoju matematičkog mišljenja" ]
[ "" ]
doctoralThesis
[ "ARR" ]
Поповић, Бранислав; Вуловић, Ненад; Икодиновић, Небојша; Михајловић, Aлександра; Дамјановић, Радојко; Употреба манипулатива у развоју математичког мишљења; Употреба манипулатива у развоју математичког мишљења;
[ "https://nardus.mpn.gov.rs/bitstream/id/51078/Disertacija5082.pdf", "https://nardus.mpn.gov.rs/bitstream/id/51079/Izvestaj_Radojko_Damjanovic_Pedagoski.pdf", "http://nardus.mpn.gov.rs/bitstream/id/51078/Disertacija5082.pdf", "http://nardus.mpn.gov.rs/bitstream/id/51079/Izvestaj_Radojko_Damjanovic_Pedagoski.pdf", "https://fedorakg.kg.ac.rs/fedora/get/o:701/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_6897" ]
[ "" ]
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https://nardus.mpn.gov.rs/handle/123456789/18886
123456789-18886.pdf
yes
no
https://fedorabg.bg.ac.rs/fedora/get/o:24853/bdef:Content/download
no
Ispitivanje kvalitativnih i kvantitativnih karakteristika lipoproteina visoke gustine i njihove povezanosti sa markerima dislipidemije i metaboličkog sindroma:
The assessment of qualitative and quantitative characteristics of high-density lipoproteins and their associations with markers of dyslipidemia metabolic syndrome
[ "Jelić-Ivanović, Zorana" ]
[ "Dimitrijević Srećković, Vesna", "Zeljković, Aleksandra" ]
Janać, Jelena
2022-01-17T12:21:02
[ "2022-01-17T12:21:02" ]
2021-09-28
[ "http://eteze.bg.ac.rs/application/showtheses?thesesId=8465", "https://fedorabg.bg.ac.rs/fedora/get/o:24853/bdef:Content/download", "http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=49296649", "https://nardus.mpn.gov.rs/handle/123456789/18886" ]
[ "Metabolizam, struktura i funkcionalnost lipoproteina visoke gustine (high-density lipoproteins-HDL) su blisko povezani. Procenom kvalitatitvnih karakteristika HDL čestica se može dobiti detaljniji uvid u njihovu ateroprotektivnu aktivnost. U ovom istraživanju su ispitane karakteristike HDL čestica kod metaboličkog sindroma (MS) i pridruženih stanja koja predstavljaju faktore rizika za razvoj kardiovaskularnih bolesti (KVB). Uvid u remodelovanje HDL čestica je omogućen određivanjem relativne zastupljenosti pojedinačnih HDL subfrakcija, aktivnosti markera remodelovanja: lecitin-holesterol-acil transferaze (lecithin–cholesterol acyltransferase-LCAT) i holesterol-estar transfernog proteina (cholesteryl ester transfer protein-CETP), kao i koncentracije CETP. Antioksidativna funkcija HDL čestica je procenjena određivanjem paraoksonazne aktivnosti paraoksonaze 1 (PON1) i koncentracije PON1 i paraoksonaze 3 (PON3). Stepen oksidativne modifikacije antiaterogenih lipoproteinskih čestica je ispitan određivanjem koncentracije oksidovanog HDL (OxHDL). Dodatno su određene koncentracije serumskog amiloida A (SAA), leptina i adiponektina. Radi potvrde prisustva nealkoholne masne bolesti jetre (non-alcoholic fatty liver disease-NAFLD) je izračunat indeks masne jetre (fatty liver index-FLI). Dodatno. karakteristike HDL čestica su ispitane kod različitih metaboličkih fenotipova gojaznih i ispitanika sa prekomernom telesnom masom. Kod ispitanika sa MS su utvrđeni: dominacija manjih HDL subfrakcija, povišena aktivnost LCAT i koncentracija CETP. U grupi ispitanika sa MS su takođe uočeni povišena koncentracija OxHDL i vrednosti odnosa OxHDL/HDL-holesterol. Analizom karakteristika HDL čestica u odnosu na prisustvo pojedinačnih komponenti MS je utvrđeno remodelovanje u korist povećane zastupljenosti malih HDL subfrakcija u kategorijama ispitanika sa sniženom koncentracijom HDLholesterola, hipertrigliceridemijom i povećanim obimom struka. Snižena koncentracija PON3 je uočena kod ispitanika sa sniženom koncentracijom HDL-holesterola i povećanim obimom struka. Povišene vrednosti odnosa OxHDL/HDL-holesterol su utvrđene u kategorijama ispitanika sa sniženom koncentracijom HDL-holesterola, hipertrigliceridemijom i povišenom glukozom našte. Aktivnost LCAT je bila značajan prediktor povišenih vrednosti FLI. Odnos OxHDL/HDL-holesterol je bio značajan prediktor metabolički nezdravog fenotipa u kategorijama gojaznih i ispitanika sa prekomernom telesnom masom. Korelacionom analizom u celoj grupi ispitanika je utvrđeno da je odnos leptin/adiponektin je bio u pozitivnoj korelaciji sa relativnom zastupljenošću malih HDL čestica i negativno sa koncentracijom PON3. Aktivnost LCAT je pozitivno korelirala sa koncentracijom triglicerida, relativnom zastupljenošću malih HDL čestica i odnosom leptin/adiponektin. U ovom istraživanju su utvrđene izmenjene kvalitativne karakteristike HDL čestica kod MS i pridruženih stanja. Dominacija manjih HDL subfrakcija i povišen stepen oksidativne modifikacije HDL čestica su pokazatelji izmenjenih kvalitativnih odlika HDL čestica u uslovima višestrukih metaboličkih fakora rizika za KVB koji su prisutni kod MS. Dokazana je pozitivna veza između aktivnosti LCAT, kao markera remodelovanja HDL čestica, sa faktorima rizika za KVB: prisustvom MS i visokim vrednostima FLI, kao surogat markerom NAFLD. Izmenjene strukturne karakteristike HDL čestica, izražene kroz povišen stepen oksidativne modifikacije, mogu biti dodatni pokazatelj narušenog metaboličkog zdravlja gojaznih i ispitanika sa prekomernom telesnom masom. Sve ovo pokazuje da promenjene kvalitativne osobine antiaterogenih lipoproteina kod MS i srodnih stanja mogu biti dodatni element dislipidemije i faktor rizika za razvoj kardiometaboličkih komplikacija." ]
[ "High-density lipoproteins (HDL) metabolism, structure, and functionality are interrelated. Evaluation of HDL qualitative characteristics could give a more detailed insight into its atheroprotective activity. In this study, we evaluated HDL characteristics in subjects with metabolic syndrome (MS) and related conditions associated with higher risk for cardiovascular diseases (CVD). HDL particles remodeling was evaluated by estimating the relative proportion of each HDL subfraction, the activity of remodeling markers: lecithin–cholesterol acyltransferase (LCAT) and cholesteryl ester transfer protein (CETP), and CETP concentration. HDL antioxidative function was assessed through the determination of paraoxonase activity of paraoxonase 1 (PON1), as well as PON1 and paraoxonase 3 (PON3) concentrations. Oxidative modification of HDL particles was estimated as oxidatively modified HDL (OxHDL) concentration. Additionally, the concentrations of serum amyloid A (SAA), leptin and adiponectin were measured. Fatty liver index (FLI) was used as a surrogate marker for the presence of non-alcoholic fatty liver disease (NAFLD). In addition, HDL characteristics were evaluated in different metabolic phenotypes in the categories of overweight and obese subjects. Domination of smaller HDL subfractions, elevated LCAT activity, and CETP concentration, as well as increased OxHDL concentration and OxHDL/HDL-cholesterol ratio, were observed in subjects with MS. The analysis of HDL characteristics in the presence of individual MS components revealed remodeling in favor of smaller HDL subfractions in subjects with low HDL-cholesterol, hypertriglyceridemia, and elevated waist circumference. We found lower PON3 concentration in subjects with low HDL-cholesterol and elevated waist circumference. Increased OxHDL/HDLcholesterol ratio was found in subjects with low HDL-cholesterol, hypertriglyceridemia, and elevated fasting glucose. LCAT activity was positively associated with FLI. OxHDL/HDL-cholesterol ratio was a significant predictor of the metabolically unhealthy phenotype in overweight and obese subjects. In the entire group of subjects, leptin/adiponectin ratio correlated positively with the relative proportion of small HDL particles, and negatively with PON3 concentration. LCAT activity correlated positively with triglyceride concentration, relative proportion of small HDL particles, and leptin/adiponectin ratio. In this study, altered qualitative HDL characteristics in subjects with MS and related conditions were observed. Domination of smaller HDL subfractions and increased degree of HDL oxidative modification in subjects with MS indicate impaired HDL qualitative characteristics in the presence of multiple metabolic CVD risk factors associated with the presence of MS. LCAT activity was positively associated with the CVD risk factors: the presence of MS and elevated FLI values i.e. the presence of NAFLD. Altered HDL structural features, observed as an increased degree of HDL oxidative modification, can be an additional indicator of the metabolically unhealthy phenotype of overweight and obese subjects. Altered qualitative characteristics of antiatherogenic lipoproteins may represent additional components of dyslipidemia and cardiometabolic diseases risk factor in MS and related conditions." ]
application/pdf
sr
Универзитет у Београду, Фармацеутски факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by/4.0/" ]
Универзитет у Београду
[ "lipoproteini visoke gustine", "metabolički sindrom", "indeks masne jetre", "metabolički nezdrav fenotip", "lipoproteinske subfrakcije", "lecitin-holesterol-acil transferaza", "holesterol-estar transferni protein", "paraoksonaza 1", "paraoksonaza 3" ]
[ "high-density lipoproteins", "metabolic syndrome", "fatty liver index", "metabolically unhealthy phenotype", "lipoprotein subfractions", "lecithin–cholesterol acyltransferase", "cholesteryl ester transfer protein", "paraoxonase 1", "paraoxonase 3" ]
[ "Ispitivanje kvalitativnih i kvantitativnih karakteristika lipoproteina visoke gustine i njihove povezanosti sa markerima dislipidemije i metaboličkog sindroma:" ]
[ "The assessment of qualitative and quantitative characteristics of high-density lipoproteins and their associations with markers of dyslipidemia metabolic syndrome" ]
doctoralThesis
[ "BY" ]
Јелић-Ивановић, Зорана; Зељковић, Aлександра; Димитријевић Срећковић, Весна; Јанаћ, Јелена; Испитивање квалитативних и квантитативних карактеристика липопротеина високе густине и њихове повезаности са маркерима дислипидемије и метаболичког синдрома:; Испитивање квалитативних и квантитативних карактеристика липопротеина високе густине и њихове повезаности са маркерима дислипидемије и метаболичког синдрома:;
[ "http://nardus.mpn.gov.rs/bitstream/id/141862/Izvestaj_Komisije_12010.pdf", "http://nardus.mpn.gov.rs/bitstream/id/141861/Disertacija_12010.pdf", "https://fedorabg.bg.ac.rs/fedora/get/o:24853/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_18886" ]
[ "" ]
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https://nardus.mpn.gov.rs/handle/123456789/21484
123456789-21484.pdf
yes
no
https://fedorabg.bg.ac.rs/fedora/get/o:29735/bdef:Content/download
no
Imino derivatives of carbonothioic dihydrayides and cinnamic acids amides : structure-activity relationship studies
Имино деривати дихидразида тиоугљене и амида циметних киселина : корелације структуре и активности
[ "Marinković, Aleksandar D." ]
[ "Bjelogrlić, Snežana", "Prlainović, Nevena", "Mijin, Dušan", "Aranđelović, Irena" ]
Assaleh, Mohamed H.
2023-06-14T11:34:10
[ "2023-06-14T11:34:10" ]
2022-07-15
[ "https://eteze.bg.ac.rs/application/showtheses?thesesId=9137", "https://fedorabg.bg.ac.rs/fedora/get/o:29735/bdef:Content/download", "https://plus.cobiss.net/cobiss/sr/sr/bib/115398409", "https://nardus.mpn.gov.rs/handle/123456789/21484" ]
[ "Two series of compounds were synthesized in this PhD thesis: Salicylaldehyde (sal) and 2- Acetylpyridine (2ap) mono- and bis-(thiocarbohydrazones), m-TCH and b-TCH, respectively (first series), and cinnamic acids amides (second series), in overall twenty eigth compounds. All synthesized compounds are characterized using both experimental and theoretical methods. Experimental techniques include FT-IR, NMR and UV-Vis spectroscopy, as well as elemental analysis used for structural and purity characterization. The use of UV-Vis and NMR spectroscopy, and theoretical (“quantum chemical”) calculations was applied to get a deeper insight into experimental data related to the ratio of Z/E isomer and thion/thio tautomerism versus related antioxidant activity induced by water addition to dimethyl sulfoxide (DMSO) TCHs solution. Water- induced breakage of intra-molecular hydrogen bond in mono- and bis(salicylaldehyde)TCH, i.e. [(2- hydroxyphenyl)methylene]carbonothioichydrazide, m-TCHsal, and 2,2'-bis[(2- hydroxyphenyl)methylene]carbonothioic dihydrazide, b-TCHsal, lead to E to Z isomerization. Good accordance of experimental data, from 1H and 13C NMR and 2D NOESY spectra, and theoretical ones, obtained using GIAO/B3LYP-6-311G++(d,p), with respect to geometrical E:Z isomer ratio, e.g. 81:19 for m-TCHsal was obtained. Destabilization of the ground state lowers bond dissociation enthalpy (BDE) for 11 kcal/mol, and as consequence leads to more extensive electron spin delocalization in Z-isomers. Additionally, 2-acetylpyridine based TCH, i.e. E-[1-(2-pyridinyl)ethylidene]-carbonothioic dihydrazide, m-TCH2ap, and 2,2'-bis[1-(2-pyridinyl)ethylidene]carbonothioic dihydrazide, b- TCH2ap, are susceptible to thione/thiol tautomerism as a phenomenon which contributes to lower BDE and effectiveness of the hydrogen transfer to DPPH∙ is facilitated in that manner. Analogously, experimental and theoretical results confirmed the shift of m-TCH2ap and b-TCH2ap to thiol form by water addition. These data were observed from the calculation of ZPE-corrected energy, enthalpy, BDEs, and the extent of radical spin delocalization of the isomers of studied compounds. Results indicate that increased participation of the thiol group in thiol/thion equilibria highly contributes to increased radical scavenging activity of compounds m-TCH2ap and b-TCH2ap. The spin density delocalization in thiol form of m-TCH2ap and b-TCH2ap occupy almost entire structure. Opposite is true for thione radicals. This fact is observed by a significant increase of antioxidant activity of all compounds, e.g. 0.67 for b-TCH2ap in DMSO and 0.13 in DMSO:H2O = 4:1 (IC50 in mM). A second part includes the synthesis of twenty four cinnamic acid amides (cinnamamides) with TCHs pharmacophore, synthesized by coupling of acid chlorides: cinnamic, 3-chlorocinnamic, 4- chlorocinnamic and 4-methoxycinnamic acid with m-TCH containing: pyridine-2-yl, salicyl, 8- hydroxyquinoline-2-yl and 2-acetyl moiety. Synthesized compounds have been investigated for their biological properties in terms of anticancer and antimycobacterial activity. Analogous synthesis was applied with 3-hydroxycinnamic acid using the same set of m-TCH and HATU coupling agent. Finally, amides based on Caffeic and Ferulic acids with m-TCH containing pyridine-2-yl and salicyl moieties were synthesized in the same manner, and used for study of their antioxidative potential. Within assessment of compounds’ ability to induce death of malignant cells, five human cell lines were treated over 24 h: colorectal adenocarcinoma (LoVo), ovarian adenocarcinoma (SkOV-3), lung adenocarcinoma (A549), breast adenocarcinoma (MCF-7) and pancreatic adenocarcinoma (AsPC-1). Obtained results showed that A549 cells were the most sensitive to tested treatments, whereas compounds 3-ClCimTCHsal and 4-ClCimTCH8OH2qu revealed superior activity and were set as the focus of a further anticancer investigation. Although 4-ClCimTCH8OH2qu acted as a more powerful inducer of apoptotic death than 3-ClCimTCHsal, both compounds in A549 cells stimulated cell cycle arrest at the G0/G1 phase, as well as activation of the intrinsic caspase cascade. A notable difference ii in mechanisms of their pro-apoptotic activity refers to the ability of 4-ClCimTCH8OH2qu to strongly arouse generation of superoxide anion in mitochondria, which was not seen in A549 cells subjected to 3-ClCimTCHsal. Evaluation of their antimigratory properties demonstrated that compound 3- ClCimTCHsal significantly inhibited mobility of A549 cells, which was not recorded in samples treated with 4-ClCimTCH8OH2qu. Finally, powerful cytotoxicity of 4-ClCimTCH8OH2qu on HaCat (human keratinocytes) and HepG-2 (hepatocellular adenocarcinoma) cells that were employed as models for skin and liver toxicity, uncovered that this compound has disadvantageous toxicity profile. On the contrary, 3-ClCimTCHsal had only a moderate impact on the vitality of HaCaT cells, and therefore proved as suitable for future investigations of its anticancer properties. The capacity of compounds to interfere with proliferation and survival of Mycobacterium tuberculosis (Mtb), which is a pathogen responsible for the development of tuberculosis (TB), was assessed on three strains from clinical isolates, each comprising a specific resistance genotype: Mtb-InhRif-S with no specific mutations associated with resistance to isoniazid (INH) and/or rifampicin (RIF), Mtb-Inh-R harboring specific mutation for resistance to RIF, and Mtb-Rif-R holding specific mutation associated with resistance to INH. After 6 days of incubation with investigated drugs, with INH and RIF as positive controls, CimTCH8OH2qu was the only one that successfully reduced Mtb viability for more than 90 % in all three treated strains. Moreover, compound CimTCH8OH2qu did not induce the death of HepG- 2 cells, which indicates its favorable hepatotoxicity profile compared to current therapeutic options for the treatment of TB. A third part of the present study included an antimicrobial study of three series of cinnamic acid amides: cinnamic, 4-chlorocinnamic and 4-methoxy cinnamic acid and m-TCH containing: pyridine- 2-yl, salicyl, 8-hydroxyquinoline-2-yl, and 2-acetyl moiety. The antimicrobial study against Enterococcus cloacae ATCC13047, Staphylococcus aureus NCTC 6571, Klebsiella pneumoniae ATCC 13883, Acinetobacter baumannii ATCC 19606, Pseudomonas aeruginosa NCTC 10662, and Escherichia coli ATCC 1175 was performed. Some of the cinnamic amides showed good in vitro activity against all strains tested, i.e. amides based on cinnamic, 4-chlorocinnamic and 4-methoxy cinnamic acid and m-TCH2ap, i.e. CimTCH2ap, 4-MeOCimTCH2ap и 4-ClCimTCH2ap. Moreover, all compounds showed acceptable to high activities with respect to A. baumannii, a widely spread opportunistic pathogen in hospitals. The most active derivative was 4-MeOCimTCH2fp, with MIC50 value of 10.4 (μmol). Additionally, in order to establish relation of structure and antibacterial activity against A. baumanii an alignment-independent 3D QSAR model was developed for the identification of pharmacophoric hotspots. In order to rationalize antimicrobial mechanism, the iron chelation capability of synthesized compounds was determined using UV-Vis spectrophotometric method. Due to the presence of strong donor sites the synthesized compounds showed strong iron chelating ability by creating complexes with the stability constant in the range from 107 to 109. Determined stability constants indicate that interaction of iron and synthesized compounds is an important step in the reaction pathway of antimicrobial activity against A. baumanii." ]
[ "У овој докторској дисертацији синтетисане су две серије једињења: салицилалдехид и 2-ацетилпиридин моно- и дитиокарбохидразони, TCH (прва серија), и амиди циметних киселина (друга серија), укупно двадесетосам једињења. У првом делу дисертације, применом експерименталних и теоријских метода су окарактерисана сва синтетисана једињења. Експерименталне технике су укључиле: FT- IR, NMR и UV-Vis спектроскопију, као и елементалну анализу. Употреба UV-Vis и NMR спектроскопије и теоријских прорачуна примењена је да би се добио бољи увид у експерименталне податке који се односе на однос Z/E изомера и повећану антиоксидативну активност након додатка воде у раствор диметил-сулфоксида (ДМСО) TCHs. Вода раскида интрамолекуларне водоничне везе у [(2-хидроксифенил)- метилен]карботиохидразид, m-TCHsal и 2,2'-bis[(2-хидроксифенил)метилен]карботио- дихидразид, b-TCHsal, који доводе до E и Z изомеризације. Резултати из 1H и 13C NMR и 2D NOESY спектара и теоријских израчунавања, добијених коришћењем GIAO/B3LYP- 6-311G++(d,p) базиз сета, указују на 81:19 однос E:Z изомера за m-TCHsal. Такође, израчунато је да услед дестабилизације основног стања, енталпија дисоцијације везе (енгл. Bond Dissociation Energy, BDE) је мања за 11 kcal/mol, а делокализација спина електрона у Z -изомерима је значајнија. Поред тога, Е-[1-(2-пиридинил)етилиден]карботиохидразид, m-TCH2ap, и 2,2'-bis[1- (2-пиридинил)етилиден]карботио-дихидразид, b-TCH2ap, су подложни тион/тиол таутомеризацији што доприноси смањењу BDE и тиме олакшава пренос атома водоника у DPPH∙ тесту. Експериментални и теоријски резултати потврдили су да тион/тиол равнотежа, код m-TCH2ap и b-TCH2ap, додавањем воде помера равнотежу ка тиолном облику. Ови подаци су добијени из израчунавања ZPE-кориговане енергије, енталпије, BDE и степена делокализације спина радикала одговарајућих таутомера. Резултати показују да повећан удео тиолне групе у великој мери доприноси повећању активности једињења m-TCH2ap и b-TCH2ap. Густина спина радикала у тиолном облику једињења m-TCH2ap и b-TCH2ap делокализована је скоро преко целе структуре, што није случај код тион облика. Ова чињеница објашњава значајно повећање антиоксидативне активности, нпр. IC50 за b-TCH2ap је 0,67 у ДМСО и 0,13 у ДМСО:H2O = 4:1 (у mM). Други део дисертације је укључивао синтезу дванаест амида циметне киселине укључујући TCH фармакофоре, синтетисаних купловањем хлорида киселина: циметне, 3-хлорциметне и 4-хлорциметне киселине, као и m-TCH који садрже: пиридин-2-ил, салицил, 8-хидроксихинолин-2-ил и 2-ацетил групе. Синтетисаним једињењима је испитиван спектар биолошких активности укључујући антиканцерску и антимикобактеријску активност. Аналогна синтеза је примењена са 3- хидроксициметном киселином коришћењем истог сета m-TCH и HATU средства за купловање. На исти начин су синтетисани амиди кафеинске и ферулинске киселине са m-TCH који садрже пиридин-2-ил и салицил делове који су коришћени за одређивање антиоксидативнoг потенцијала. У оквиру процене способности једињења да индукују смрт малигних ћелија, пет хуманих ћелијских линија је третирано током 24 сата: колоректални аденокарцином (LoVo), аденокарцином јајника (SkOV-3), аденокарцином плућа (А549), аденокарцином дојке (MCF-7) и аденокарцином панкреаса (AsPC-1). Добијени резултати су показали да су ћелије А549 биле најосетљивије на тестирана једињења док су једињења 3-ClCimTCHsal и 4-ClCimTCH8OH2qu показала супериорну iv активност и изабрана су за даља истраживања антиканцерске активности. Иако је 4- ClCimTCH8OH2qu деловао као снажнији индуктор апоптозне смрти од 3-ClCimTCHsal, оба једињења у А549 ћелијама су стимулисала заустављање ћелијског циклуса у G0/G1 фази, као и активацију интринзичне каспазне каскаде. Значајна разлика у механизмима њихове про-апоптозне активности односи се на способност 4-ClCimTCH8OH2qu да снажно побуди стварање супероксидног анјона у митохондријама, што није детектовано у ћелијама А549 подвргнутим 3-ClCimTCHsal. Процена њихових антимиграционих својстава показала је да једињење 3-ClCimTCHsal значајно инхибира покретљивост А549 ћелија, што није забележено у узорцима третираним са 4-ClCimTCH8OH2qu. Висок проценат ћелијске смрти које је изазвало једињење 4-ClCimTCH8OH2qu у ћелијама HaCaT (хумани кератиноцити) и HepG-2 (хумани хепатоцити), коришћених као модели за процену могућих нежељених дејстава, указало је да ово једињење има неповољан токсиколошки профил. Напротив, 3-ClCimTCHsal је имао само умерен утицај на виталност HaCaT ћелија и стога се показао погодним за будућа истраживања његових антиканцерских својстава. Капацитет једињења да омета пролиферацију Mycobacterium tuberculosis (Mtb), патогена одговорног за развој туберкулозе (ТБ), процењен је на три соја из клиничких изолата, од којих сваки садржи специфичан генотип отпорности на лекове који се користе у првој линији анти-ТБ терапије: Mtb-InhRif-S без специфичних мутација повезаних са резистенцијом на изониазид (INH) и/или рифампицин (RIF), Mtb-Inh-R који има специфичну мутацију за отпорност на INH, и Mtb-Rif-R који има специфичну мутацију повезану са отпорношћу на RIF. После шест дана инкубације са испитиваним лековима и INH и RIF као позитивним контролама, CimTCH8OH2qu је био једини који је успешно смањио раст и размножавање Mtb за више од 90% у сва три третирана соја. Штавише, једињење CimTCH8OH2qu није изазвало смрт HepG-2 ћелија, што указује на његов повољан профил хепатотоксичности за разлику од тренутно доступних терапијских опција за лечење ТБ. Трећи део ове студије обухватао је испитивање антибактеријске активности четири серије амида: циметне, 4-хлороциметне и 4-метокси циметне киселине које у амидном делу садрже: пиридин-2-ил, салицил, 8-хидрокси хинолин-2-ил и 2-ацетил групу. Антибактеријска студија изведена је на Enterococcus cloacae ATCC13047, Staphylococcus aureus NCTC 6571, Klebsiella pneumoniae ATCC 13883, Acinetobacter baumannii ATCC 19606, Pseudomonas aeruginosa NCTC 10662, and Escherichia coli ATCC 1175, применом методе разблаживања. Поједини амиди циметне киселине су показали добру in vitro активност према свим испитиваним сојевима, односно амиди циметне, 4-хлорциметне и 4-метоксициметне киселине са 2-ацетилпиридинил групом, тј. CimTCH2ap, 4- MeOCimTCH2ap и 4-ClCimTCH2ap. Штавише, сва једињења су показала значајну активност у односу на A. baumannii, широко распрострањени опортунистички интрахоспитални патоген. Најактивнији дериват био је 4-MeOCimTCH2fp, чија је минимална инхибиторна концентрација способна да инхибира раст и размножавање за 50 % (МИК50) износила 10,4 μmol. Поред тога, да би се успоставила веза између структуре и антибактеријске активности против A. baumannii, развијен је 3D QSAR модел (an alignment-independent 3D QSAR model) за идентификацију битних фармакофорa. У циљу рационализације антимикробног механизма, способност хелације (координације) гвожђа синтетисаних једињења је одређена UV-Vis спектрофотометријском методом. Због присуства јаких донорских места, синтетисана једињења су показала високу способност хелације гвожђа стварањем комплекса са константом стабилности у опсегу од 107 до 109. Вредности константи стабилности указује да је интеракција гвожђа са овим једињењима важан корак у метаболитичком v путу што је потврђено тиме што је антибактеријска активност према A. Baumannii у корелацији са променом вредности константе стабилности." ]
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Универзитет у Београду, Технолошко-металуршки факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Београду
[ "Thiocarbohydrazide", "Cinnamic acid amides", "E/Z isomerism", "Tautomerism", "Antioxidant Activity", "Antibacterial activity", "Mycobacterium tuberculosis", "Anticancer", "Hepatotoxicity", "Acinetobacter baumannii", "3D QSAR" ]
[ "Тиокарбохидразиди", "Амиди циметне киселине", "E/Z изомеризација", "Таутомеризациjа", "Антиоксидатвна активност", "Антибактеријска активност", "Mycobacterium tuberculosis", "Антиканцер", "Хепатоксичност", "Acinetobacter baumannii", "3D QSAR" ]
[ "Imino derivatives of carbonothioic dihydrayides and cinnamic acids amides : structure-activity relationship studies" ]
[ "Имино деривати дихидразида тиоугљене и амида циметних киселина : корелације структуре и активности" ]
doctoralThesis
[ "BY-NC-ND" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/151222/Disertacija_13584.pdf", "http://nardus.mpn.gov.rs/bitstream/id/152790/Referat.pdf", "https://fedorabg.bg.ac.rs/fedora/get/o:29735/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_21484" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
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[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/21676
123456789-21676.pdf
yes
no
https://fedorakg.kg.ac.rs/fedora/get/o:1622/bdef:Content/download
no
Polimorfizmi gena za galektin-3 kod bolesnika u terminalnoj fazi renalne insuficijencije
Galectin-3 gene polymorphisms in patients with end-stage renal failure
[ "Ljujić, Biljana" ]
[ "Lazarević, Tatjana", "Đukić, Aleksandar", "Maksimović, Nela", "Miletić-Kovačević, Marina" ]
Kovačević, Zoran
2023-09-06T12:19:17
[ "2023-09-06T12:19:17" ]
2022
[ "http://eteze.kg.ac.rs/application/showtheses?thesesId=8663", "https://fedorakg.kg.ac.rs/fedora/get/o:1622/bdef:Content/download", "https://nardus.mpn.gov.rs/handle/123456789/21676" ]
[ "Svrha istraživanja Galektin 3 (engl. Galectin 3, Gal-3) igra značajnu ulogu u razvoju hronične renalne insuficijencije, posebno u terminalnoj fazi renalne insuficijencije (TFRI). Cilj studije je bio da se ispita povezanost između Gal-3 i biohemijskih parametara i primarne bolesti kod pacijenata sa TFRI, istraživanjem polimorfizama LGALS3rs4644, rs4652 i rs11125. U studiju je uključeno ukupno 108 pacijenata sa TFRI-om i 38 zdravih kontrola. Genotipizacija gena Gal-3 koji je kodiran genom LGALS3 (engl. Lectin, Galactoside-Binding, Soluble, 3), rs4644, rs4652 i rs11125 je izvršena metodom reakcije lančane polimerizacije-restrikcionog fragmenta-polimorfizmom dužine (PCR–RFLP). Rezultati Multivarijantnom logističkom regresionom analizom, pokazano je da su genotipovi LGALS3 rs4644 CC i rs4652 AA značajno povezani sa većim rizikom za snižene vrednosti hemoglobina, viši nivo paratiroidnog hormona (paratireoidni hormon, PTH) kao i pojavu dijabetes melitusa i arterijske hipertenzije. CAA haplotip je bio značajno češći kod pacijenata sa dijabetesom, niskim nivoom hemoglobina i normalnim nivoom PTH. Takođe je primećeno da je ACT haplotip bio češći kod pacijenata sa smanjenom jačinom glomerulske filtracije (JGF), niskim PTH i normalnim nivoom hemoglobina Otkrili smo da polimorfizam gena LGALS3rs4644 i rs4652 može biti uključen u patogenezu i pojavu komplikacija kod pacijenata sa TFRI i stoga se može smatrati novim genetskim faktorom rizika u ovoj populaciji." ]
[ "Galectin 3 plays a significant role in the development of chronic renal failure, particularly end-stage renal disease (ESRD). The aim of our study was to investigate the association between Gal-3 and biochemical parameters and primary disease in ESRD patients, by exploring the polymorphisms LGALS3 rs4644, rs4652, and rs11125. A total of 108 ESRD patients and 38 healthy controls were enrolled in the study. Genotyping of LGALS3 gene rs4644, rs4652, and rs11125 polymorphisms was performed by polymerase chain reaction– restriction fragment length polymorphism (PCR-RFLP). By multivariate logistic regression analysis, we found that LGALS3 rs4644 CC and rs4652 AA genotypes were significantly associated with a higher risk for lower hemoglobin, higher level of parathyroid hormone, and also occurrence of diabetes mellitus and arterial hypertension. The CAA haplotype was significantly more common in patients with diabetes, low hemoglobin level, and normal PTH level. It has been observed as well that the ACT haplotype was more common in patients with low glomerular filtration, low PTH, and normal hemoglobin level. We found that the LGALS3 rs4644 and rs4652 gene polymorphism may be involved in the pathogenesis and appearance of complications in ESRD patients and thus could be considered a new genetic risk factor in this population." ]
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Универзитет у Крагујевцу, Факултет медицинских наука
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Крагујевцу
[ "galektin 3", "polimorfizmi", "terminalna faza renalne insuficijencije", "dijabetes melitus", "arterijska hipertenzija" ]
[ "galectin 3", "polymorphisms", "end-stage renal disease", "diabetes mellitus", "arterial hypertension" ]
[ "Polimorfizmi gena za galektin-3 kod bolesnika u terminalnoj fazi renalne insuficijencije" ]
[ "Galectin-3 gene polymorphisms in patients with end-stage renal failure" ]
doctoralThesis
[ "BY-NC-ND" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/151858/Disertacija.pdf", "https://fedorakg.kg.ac.rs/fedora/get/o:1622/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_21676" ]
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https://nardus.mpn.gov.rs/handle/123456789/21650
123456789-21650.pdf
yes
no
https://fedorakg.kg.ac.rs/fedora/get/o:1580/bdef:Content/download
no
Uloga ćelijske senescencije indukovane onkogenima u malignoj transformaciji i progresiji tumora dojke
The role of oncogene-induced senescence in malignant transformation and breast tumor progression
[ "Mitrović, Slobodanka" ]
[ "Stanković, Vesna", "Mijović, Milica", "Spasić, Marko" ]
Jovanović, Dalibor
2023-09-06T12:18:42
[ "2023-09-06T12:18:42" ]
2022
[ "http://eteze.kg.ac.rs/application/showtheses?thesesId=8621", "https://fedorakg.kg.ac.rs/fedora/get/o:1580/bdef:Content/download", "https://nardus.mpn.gov.rs/handle/123456789/21650" ]
[ "Uprkos značaju pojedinih prognostičkih faktora, njihova tačnost u proceni ishoda i određivanju strategija lečenja obolelih od karcinoma dojke je ograničena. Stoga bi definisanje novih molekularnih biomarkera moglo pružiti pouzdaniji pristup u predviđanju prognoze ove bolesti. Cilj ove studije je ispitivanje ekspresije markera p16, p53, p21, pRb i GLB1 u benignim i malignim promenama dojke, kao i njihovog učešća u malignoj transformaciji. Istraživanje je obuhvatilo analizu tkivnog materijala benignih i malignih promena pacijentkinja operisanih u UKC Kragujevac. Na H&E obojenim preparatima definisani su svi makro i mikromorfološki prognostički faktori (histološki tip i gradus tumora, veličina, nodalni status, dezmoplazija, nekroza, mononuklearna reakcija i td.) Imunohistohemijski, primenom antitela (p16,p53,p21,pRb,GLB1), određivana je tkivna ekspresija markera semikvantitativnim očitavanjem pozitivne reakcije. Definisanjem cut off vrednosti, karcinomi su svrstavani u pozitivnu i negativnu grupu za svaki analizirani marker. Ekspresija svih markera raste sa progresijom citoloških promena u epitelu. Njihova ekspresija je u pozitivnoj korelaciji sa različitim promenama u dojci, sa proliferativnim indeksom i HER2+ tumorima. Ekspresija p16, pRb, p21, GLB1 je najveća u HER2+ karcinomima dojke, dok je ekspresija p53 najveća u TNBC. Značajna korelacija je utvrđena između ekspresije p16 i p53, p21 i pRb, p21 i GLB1, kao i između pRb i GLB1 u invazivnom karcinomu. Analizirani markeri igraju važnu ulogu u proliferaciji, malignoj transformaciji, kao i u progresiji karcinoma dojke, što ih preproručuje za dalja istraživanja i moguće korišćenje u dijagnostičke, prognostičke i prediktivne svrhe." ]
[ "Despite the importance of certain prognostic factors, their accuracy in assessing outcomes and determining treatment strategies for breast cancer patients is limited. Therefore, the definition of new molecular biomarkers could provide a more reliable approach for prediction of the prognosis of this disease. The aim of this study was to examine the expression of markers p16, p53, p21, pRb and GLB1 in benign and malignant breast changes, as well as their participation in malignant transformation. The research included the analysis of tissue material of benign and malignant changes in patients operated at the University Clinical Center Kragujevac. All macro and micromorphological prognostic factors (histological type and grade of tumor, size, nodal status, desmoplasia, necrosis, mononuclear reaction, etc.) were defined on H&E stained preparations. Immunohistochemically, using antibodies (p16, p53, p21, pRb, GLB1) tissue expression of markers were determined by a semiquantitative reading of a positive reaction. By defining cut-off values, cancers were classified into positive and negative groups for each analyzed marker. The expression of all markers increased with the progression of cytological changes in the epithelium. Their expression positively correlated with various changes in the breast, with the proliferative index and HER2+ tumors. The expression of p16, pRb, p21, GLB1 is the highest in HER2+ breast cancers, while the expression of p53 is the highest in TNBC. A significant correlation was found between the expression of p16 and p53, p21 and pRb, p21 and GLB1, as well as between pRb and GLB1 in invasive cancer. The analyzed markers play an important role in proliferation, malignant transformation, as well as in the progression of breast cancer, which recommends them for further research and possible use for diagnostic, prognostic and predictive purposes." ]
application/pdf
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Универзитет у Крагујевцу, Факултет медицинских наука
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nd/4.0/" ]
Универзитет у Крагујевцу
[ "karcinom dojke", "ćelijska senescencija", "inhibitor ciklin zavisnih kinaza p16", "p53 tumor supresorski protein", "inhibitor ciklin zavisnih kinaza p21", "protein retinoblastoma" ]
[ "breast cancer", "cellular senescence", "cyclin-dependent kinase inhibitor p16", "tumor suppressor protein p53", "cyclin-dependent kinase inhibitor p21", "retinoblastoma protein." ]
[ "Uloga ćelijske senescencije indukovane onkogenima u malignoj transformaciji i progresiji tumora dojke" ]
[ "The role of oncogene-induced senescence in malignant transformation and breast tumor progression" ]
doctoralThesis
[ "BY-ND" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/151884/Disertacija.pdf", "https://fedorakg.kg.ac.rs/fedora/get/o:1580/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_21650" ]
[ "" ]
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https://nardus.mpn.gov.rs/handle/123456789/21682
123456789-21682.pdf
yes
no
https://fedorakg.kg.ac.rs/fedora/get/o:1628/bdef:Content/download
no
Ispitivanje uticaja standardizovanog ekstrakta aronije na morfološke karakteristike jajnika, hormonski i oksidacioni status kod pacova sa sindromom policističnih jajnika
Evaluation of the effect of standardized aronia extract on ovarian morphological characteristics, hormonal and oxidative status in rats with polycystic ovary syndrome
[ "Joksimović Jović, Jovana" ]
[ "Tomović, Marina", "Dimitrijević, Aleksandra", "Raičević, Saša" ]
Rudić, Jovan
2023-09-06T12:19:23
[ "2023-09-06T12:19:23" ]
2023
[ "http://eteze.kg.ac.rs/application/showtheses?thesesId=8669", "https://fedorakg.kg.ac.rs/fedora/get/o:1628/bdef:Content/download", "https://nardus.mpn.gov.rs/handle/123456789/21682" ]
[ "Sindrom policističnih jajnika (engl. Polycystic Ovary Syndrome - PCOS) predstavlja najčešći endokrinološki i metabolički poremećaj žena reproduktivne dobi i vodeći uzrok anovulatornog infertiliteta. Iako je poslednjih godina dosta razjašnjeno o patogenezi, dijagnozi, kliničkim manifestacijama i terapiji PCOS, još uvek postoje mnoge nedoumice i posledične neizvesnosti u izboru terapijskog pristupa u kliničkoj praksi. Metformin (MET) je jedna od prvih terapijskih opcija za tretman PCOS. Neželjeni efekti metformina se vezuju za gastrointestinalne tegobe, koje su nekada razlog prestanka upotrebe. Nedavne studije sugerišu da komplementarni i alternativni tretmani, uključujući biljne lekove, mogu ublažiti simptome PCOS. Aronia Melanocarpa L., koja se obično naziva crna aronija, pripada porodici Rosaceae. Antioksidativna aktivnost crne aronije je prepoznata u mnogim studijama. Ovi podaci su nas doveli do ideje da istražimo potencijalne prednosti primene standardizovanog ekstrakta aronije (SEA) u dehidroepiandrosteronom-indukovanom modelu PCOS kod pacova. Takođe, imali smo za cilj da istražimo sinergističke efekte SEA i MET terapije u ublažavanju reproduktivnih i metaboličkih abnormalnosti kod PCOS. Naši nalazi su potvrdili da je SAE sam ili u kombinaciji sa MET bio u stanju da ublaži reproduktivne i metaboličke poremećaje u modelu PCOS pacova izazvanog DHEA. Efekat samostalno primenjenog SAE nije značajno uticao na efekte MET kod PCOS. Potvrđen je sinergistički efekat ova dva agensa u većini procenjenih karakteristika PCOS. Ovi rezultati mogu poslužiti kao osnova za dalja klinička ispitivanja u vezi sa primenom SAE kod žena sa PCOS kako bi se procenio poseban doprinos ovog ekstrakta reproduktivnim i metaboličkim profilima u ovoj populaciji pacijenata, posebno kod onih sa gojaznim fenotipom PCOS." ]
[ "Polycystic Ovary Syndrome (PCOS) is the most common endocrinological and metabolic disorder in reproductive age women, and it is the leading cause of anovulatory infertility. Although the pathogenesis, diagnosis, clinical manifestations and therapy of PCOS have been clarified in recent years, there are still many doubts and consequent uncertainties in the choice of therapeutic approach in clinical practice. Metformin (MET) is one of the first therapeutic options for the treatment of PCOS. Adverse effects of MET are related to gastrointestinal complaints, which are sometimes the reason for cessasion of use. Recent studies suggest that complementary and alternative treatments, including herbal medicines, can alleviate PCOS symptoms. Aronia Melanocarpa L., commonly called black chokeberry, belongs to the Rosaceae family. The antioxidant activity of black chokeberry has been recognized in many studies. These data led us to the idea to investigate the potential benefits of using a standardized Aronia extract (SEA) in a dehydroepiandrosterone-induced PCOS model in rats. Also, we aimed to investigate the synergistic effects of SEA and MET therapy in alleviating reproductive and metabolic abnormalities in PCOS. Our findings confirmed that SAE alone or in combination with MET was able to alleviate reproductive and metabolic disorders in a DHEA-induced PCOS rat model. The effect of selfadministered SAE did not significantly influence the effects of MET in PCOS. A synergistic effect of these two agents has been confirmed in most of the PCOS features assessed. These results may serve as a basis for further clinical trials regarding the use of SAE in women with PCOS to evaluate the specific contribution of this extract to reproductive and metabolic profiles in this patient population, especially those with an obese PCOS phenotype." ]
application/pdf
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Универзитет у Крагујевцу, Факултет медицинских наука
[ "" ]
[ "openAccess" ]
[ "" ]
Универзитет у Крагујевцу
[ "Aronia Melanocarpa", "animalni model", "antioksidansi", "hidroepiandrosteron", "estrus", "metformin", "oksidativni stres", "sindrom policističnih jajnika", "pacovi", "testosteron" ]
[ "Aronia melanocarpa", "animal model", "antioxidants", "dehydroepiandrosterone", "estrus", "metformin", "oxidative stress", "polycystic ovary syndrome", "rats", "testosterone" ]
[ "Ispitivanje uticaja standardizovanog ekstrakta aronije na morfološke karakteristike jajnika, hormonski i oksidacioni status kod pacova sa sindromom policističnih jajnika" ]
[ "Evaluation of the effect of standardized aronia extract on ovarian morphological characteristics, hormonal and oxidative status in rats with polycystic ovary syndrome" ]
doctoralThesis
[ "" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/151852/Disertacija.pdf", "https://fedorakg.kg.ac.rs/fedora/get/o:1628/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_21682" ]
[ "" ]
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[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/21679
123456789-21679.pdf
yes
no
https://fedorakg.kg.ac.rs/fedora/get/o:1625/bdef:Content/download
no
Instrumenti za merenje znanja i stavova profesionalnih vozača o supstancama koje mogu da utiču na psihomotorne sposobnosti i analiza faktora povezanih sa rezultatima merenja
Instruments for measuring knowledge and attitudes of professional drivers about substances that can affect psychomotor abilities and analysis of the factors related to the measurement results
[ "Folić, Marko" ]
[ "Janković, Slobodan", "Vezmar Kovačević, Sandra", "Milosavljević, Miloš" ]
Antonić, Roland
2023-09-06T12:19:20
[ "2023-09-06T12:19:20" ]
2023
[ "http://eteze.kg.ac.rs/application/showtheses?thesesId=8666", "https://fedorakg.kg.ac.rs/fedora/get/o:1625/bdef:Content/download", "https://nardus.mpn.gov.rs/handle/123456789/21679" ]
[ "UVOD: Često propisivani i korišćeni lekovi, pored relevantnih terapijskih efekata, mogu imati i negativan uticaj na psihomotorne i kognitivne funkcije, odnosno značajno uticati na sposobnost vožnje. Ovakav uticaj mogu ispoljiti i alkohol i druge psihoaktivne supstance, što može dovesti u pitanje i bezbednost saobraćaja. MATERIJAL I METODE: Istraživanje je realizovano po tipu multicentrične retrospektivno-prospektivne studije preseka (Republika Srbija i Bosna i Hercegovina) na uzorku 221 profesionalnog vozača, oba pola, starosti od 20 do 65 godina, u periodu od 2017. do 2022. godine. U ispitivanju su upotrebljena dva upitnika, osmišljena od strane članova istraživačkog tima, putem kojih su ispitani znanje i stavovi o uticaju lekova i ostalih karakterističnih susptanci na vožnju, ali i potencijalni faktori koji utiču na znanje i stavove ispitanika. Za oba upitnika je urađena validacija, utvrđena pouzdanost i interna konzistentnost, a potom i faktorska analiza. REZULTATI: Rezultati ove studije su pokazali nezadovoljavajući stepen znanja i neadekvatnost stavova profesionalnih vozača o uticaju različitih supstanci na psihomotorne sposobnosti, kao i to da brojni faktori mogu uticati na pomenute aspekte, što može biti od posebnog značaja u kreiranju strategije primene preventivnih i pravovremenih korektivnih mera na polju unapređenja bezbednosnih aspekata u saobraćaju. Upitnici upotrebljeni u studiji pokazuju dobru pouzdanost i internu konzistentnost i predstavljaju pouzdane i validne instrumente za procenu istraživačkog pitanja. ZAKLjUČAK: Adekvatna implementacija rezultata ove studije može biti od velikog značaja na polju poboljšanja različitih aspekata bezbednosti u saobraćaju." ]
[ "INTRODUCTION: Frequently prescribed and used medicines, beside to relevant therapeutic effects, can have a negative impact on psychomotor and cognitive functions, and significantly affect driving ability. Alcohol and other psychoactive substances can also have this effects, which may jeopardize traffic safety. MATERIAL AND METHODS: The research was conducted as a multicenter retrospectiveprospective cross-sectional study (Republic of Serbia and Bosnia and Herzegovina) on a sample of 221 professional drivers, both sexes, aged 20 to 65, in the period from 2017 to 2022. Two questionnaires were used in the study, designed by research team members, which examined the knowledge and attitudes about the impact of medicines and other characteristic substances on driving and factors with potential influence on knowledge and attitudes of the respondents. Validation was performed for both questionnaires, reliability and internal consistency were determined, and then factorial analysis. RESULTS: The results of this study showed an unsatisfactory level of knowledge and inadequacy of attitudes of professional drivers on the impact of various substances on driving ability, and that many factors can affect these aspects, which may be of particular importance in creating a strategy for the application of preventive and corrective measures in the field of improving traffic safety. The questionnaires used in the study show good reliability and internal consistency and represent a reliable and valid tool for assessing the research question. CONCLUSION: Adequate implementation of the results of this study can be of great importance in the field of improving various aspects of traffic safety." ]
application/pdf
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Универзитет у Крагујевцу, Факултет медицинских наука
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Крагујевцу
[ "profesionalni vozači", "lekovi", "znanje", "stavovi", "upitnici", "faktori rizika" ]
[ "professional drivers", "medicines", "knowledge", "attitudes", "questionnaires", "risk factors" ]
[ "Instrumenti za merenje znanja i stavova profesionalnih vozača o supstancama koje mogu da utiču na psihomotorne sposobnosti i analiza faktora povezanih sa rezultatima merenja" ]
[ "Instruments for measuring knowledge and attitudes of professional drivers about substances that can affect psychomotor abilities and analysis of the factors related to the measurement results" ]
doctoralThesis
[ "BY-NC-ND" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/151855/Disertacija.pdf", "https://fedorakg.kg.ac.rs/fedora/get/o:1625/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_21679" ]
[ "" ]
[ "" ]
[ "" ]
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[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/17749
123456789-17749.pdf
yes
no
https://fedorakg.kg.ac.rs/fedora/get/o:1286/bdef:Content/download
no
Uticaj tretmana senzorne integracije kod adolescenata i odraslih osoba sa poremećajima autističnog spektra
The Effects of Sensory Integration Treatment in Adolescents and Adults with Autism Spectrum Disorder
[ "Pejović-Milovančević, Milica" ]
[ "Obradović, Slobodan", "Stojanović, Jasmina", "Vuković, Olivera" ]
Novaković, Neda
2020-12-30T12:24:42
[ "2020-12-30T12:24:42" ]
2020-10-07
[ "http://eteze.kg.ac.rs/application/showtheses?thesesId=7756", "https://fedorakg.kg.ac.rs/fedora/get/o:1286/bdef:Content/download", "https://nardus.mpn.gov.rs/handle/123456789/17749" ]
[ "" ]
[ "" ]
application/pdf
sr
Универзитет у Крагујевцу, Факултет медицинских наука
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc/4.0/" ]
Универзитет у Крагујевцу
[ "poremećaj iz spektra autizma", "senzorna integracija", "tretman senzorne integracije", "Snoezelen soba", "izraženost simptoma", "repetitivno/stereotipno ponašanje", "poremećaj socijalne responzivnosti" ]
[ "autism spectrum disorder", "sensory integration", "sensory integration treatment", "Snoezelen room", "severity of symptoms", "repetitive/stereotyped behaviour", "social responsiveness disorder" ]
[ "Uticaj tretmana senzorne integracije kod adolescenata i odraslih osoba sa poremećajima autističnog spektra" ]
[ "The Effects of Sensory Integration Treatment in Adolescents and Adults with Autism Spectrum Disorder" ]
doctoralThesis
[ "BY-NC" ]
Пејовић-Милованчевић, Милица; Обрадовић, Слободан; Стојановић, Јасмина; Вуковић, Оливера; Новаковић, Неда; Утицај третмана сензорне интеграције код адолесцената и одраслих особа са поремећајима аутистичног спектра; Утицај третмана сензорне интеграције код адолесцената и одраслих особа са поремећајима аутистичног спектра;
[ "https://nardus.mpn.gov.rs/bitstream/id/67643/Disertacija.pdf", "https://nardus.mpn.gov.rs/bitstream/id/67644/Neda_Novakovic_Medicina.pdf", "https://fedorakg.kg.ac.rs/fedora/get/o:1286/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_17749" ]
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Uvod: Poremećaji iz spektra autizma (PSA) karakterišu teškoće u socijalnim interakcijama, socijalnoj komunikaciji i repetitivno/stereotipno ponašanje uz izbegavanje promena. Najnoviji klasifikacioni sistem Američke Psihijatrijske Asocijacije (APA) DSM – 5 uključuje senzorne probleme kao dijagnostički kriterijum. Tretmani bazirani na senzornoj integraciji podrazumevaju aktivno učešće korisnika tretmana u multisenzornom okruženju - „Snoezelen“ sobi dizajniranoj da obezbedi višestruke mogućnosti za senzornu stimulaciju. Cilj: Utvrđivanje efekata tretmana na stereotipno/repetitivno ponašanje, socijalnu responzivnost i nivo senzorne integracije kao i na stepen izraženosti simptoma kod adolescenata i odraslih osoba sa PSA. Materijal i metod: Istraživanje je sprovedeno u periodu od 3 meseca u Beogradu, kod 40 ispitanika sa PSA, podeljenih u dve grupe, ekperimentalnu koja je imala 36 tretmana i kontrolnu bez tretmana. Studija se sprovodila u dve faze. Pre sesija: merene su funkcionalne oblasti skalama od strane defektologa i roditelja kod obe grupe ispitanika. Posle sesija: merenje je ponovljeno. Rezultati: Uticaj tretmana senzorne integracije u Snoezelen sobi kod PSA se pokazao u pogledu smanjenja stepena izraženosti simptoma i održanja i/ili smanjenja prisutnosti repetitivnog i stereotipnog ponašanja i poremećaja socijalne responzivnosti. Nije uspostavljena veza između disfunkcije senzorne integracije i izraženosti simptoma PSA. Zaključak: Ishodi istraživanja sugerišu da tretman senzorne integracije u Snoezelen sobi utiče na prevenciju pogoršanja uz poboljšanje osnovnih karakteristika PSA.
[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/18659
123456789-18659.pdf
yes
no
https://fedorakg.kg.ac.rs/fedora/get/o:1397/bdef:Content/download
no
Ispitivanje prognostičke vrednosti ekspresije metaloproteinaza matriksa 2 i 9 kod bolesnika sa planocelularnim karcinomom grkljana
Investigation of the prognostic value of matrix 2 and 9 metalloproteinase expression in patients with laryngeal squamous cell carcinoma
[ "Perić, Aleksandar" ]
[ "Stojanović, Jasmina", "Sotirović, Jelena", "Vukomanović Đurđević, Biserka" ]
Rašić, Dejan
2021-10-28T09:34:35
[ "2021-10-28T09:34:35" ]
2021-06-18
[ "http://eteze.kg.ac.rs/application/showtheses?thesesId=8325", "https://fedorakg.kg.ac.rs/fedora/get/o:1397/bdef:Content/download", "https://nardus.mpn.gov.rs/handle/123456789/18659" ]
[ "Maligni tumori larinksa čine 1-2% svih malignih tumora u humanoj populaciji. Planocelularni karcinom larinksa je češći u muškoj, nego u ženskoj populaciji, javljajući se obično između pete i sedme decenije života. Najznačajniji etiološki faktori za karcinom larinksa su pušenje duvana, konzumacija alkoholnih pića, gastroezofagealni refluks, infekcije HPV virusom, aerozagađenje, ishrana siromašna voćem i povrćem. Prognoza laringealnog karcinoma zavisi od regionalne zahvaćenosti malignom bolešću, odnosno stadijuma bolesti, koji se određuje na osnovu TNM (Tumour Node Metastasis) klasifikacije. Vreme preživljavanja se značajno smanjuje razvojem i širenjem bolesti (lokoregionalne ili udaljene metastaze). Poslednjih godina, istraživanja na molekularnom nivou otkrila su mnoge mehanizme onkogeneze. Ekspresija specifičnih tumor markera je povezana sa razvojem bolesti i biološkim ponašanjem karcinoma larinksa. Identifikacija prognostičke vrednosti nekih tumor markera bila bi od velike pomoći u odabiru terapijskog modaliteta, koji je od krucijalnog značaja za prognozu bolesti. Matriks metaloproteinaze (MMP) su familija od 23 endopeptidaze, strukturno vrlo slične proteolitičkim enzimima koji imaju sposobnost razgradnje komponenti ekstracelularnog matriksa. Stoga, MMP igraju važnu ulogu u progresiji i metastaziranju kancera. Povišene nivoe MMP se mogu detektovati u tumorskom tkivu i serumu pacijenata sa uznapredovalim karcinomom. MMP se mogu podeliti u šest subgrupa. MMP-2 i MMP-9 imaju sposobnost da unište kolagen tip IV, koji čini važnu komponentu bazalne membrane. Ovo je ključni momenat, koji je neophodan za tumorski rast i metastaziranje. Neki publikovani radovi su pokazali da MMP-2 i MMP-9 mogu igrati važnu ulogu u progresiji planocelularnog karcinoma regije glave i vrata. Identifikacija pacijenata sa visokim rizikom za razvoj maligniteta, prisustvo naknadnog lokoregionalnog recidiva, kao i postojanje regionalnih metastaza veoma su važni za prognozu bolesti, kao i za izbor najboljeg načina lečenja. Cilj ovog istraživanja je bio da proceni klinički značaj MMP-2 i MMP-9 ekspresije u tkivnim uzorcima planocelularnog karcinoma larinksa, poredeći glotični i subglotični subregion. U istraživanje je bilo uključeno ukupno 140 bolesnika, od toga 70 sa patohistološki verifikovanim planocelularnim karcinomom larinksa i 70 sa hroničnim laringitisom. Ispitanici sa karcinomom larinksa su razvrstani po grupama u odnosu na: lokalizaciju tumora u larinksu (supraglotična, glotična); TNM stadijuma bolesti (T1/T2, T3/T4, N0 odnosno N+, M0 odnosno M+); stadijum bolesti (I, II, III i IV); stepen diferentovanosti ćelija tumora (dobro, umereno, slabo); načina ćelijskog rasta (vegetantni, infiltrativni, mešoviti); razvoj lokoregionalnog recidiva (sa ili bez recidiva bolesti); prisustva perineuralne invazije (sa ili bez perineuralne invazije); prisustva limfovaskularne invazije (sa ili bez limfovaskularne invazije); petogodišnje preživljavanje (sa ili bez petogodišnjeg preživljavanja). Pacijenti sa karcinomom larinksa su dijagnostikovani, lečeni i praćeni u periodu od minimum 5 godina, između 2010. i 2017. u Klinici za otorinolaringologiju. Kontrolnu grupu su činili pacijenti kod kojih je, u istom periodu, dijagnostikovan i lečen hronični laringitis. Patohistološka verifikacija tumora larinksa i imunohistohemijske analize vršene su u Institutu za patologiju, od strane istih, iskusnih patologa. Kriterijum za uključivanje u studiju su bili patohistološki verifikovani planocelularni karcinomi larinksa i patohistološki verifikovane hronične promene u laringealnoj sluznici. Kriterijumi za isključenje iz studije su bila druga maligna oboljenja, prethodno sprovedena zračna ili polihemioterapija ili već ranije izvršeno hirurško uklanjanje tumora. Zatim, sistemske bolesti sa zahvatanjem larinksa, benigni pseudotumori larinksa. Prosečna starost pacijenata je bila 59,41 (±7,1), sa rasponom od 40 do 79 godina. Bilo je 60 (85,7%) muškaraca i 10 (14,3%) žena. Karcinom glotične regije bio je zastupljen kod 45 (64,3%) pacijenata, prosečne starosti 59,7 (±6,8) godina, a supraglotičnog regiona kod 25 (35,7%) pacijenta, prosečne starosti 58,8% (±7,7). Većina pacijenata sa glotičnim karcinomom bili su u T1/T2 stadijumu bolesti, dok je većina pacijenta sa supraglotičnim karcinomom bila u T3/T4 stadijumu. Nije otkrivena značajna razlika u petogodišnjem preživljavanju između pacijenata sa glotičnim i supraglotičnim karcinomom. Rezultati su pokazali značajnu višu MMP-2 i MMP-9 ekspresiju i u epitelu i u stromi tkivnih uzoraka karcinoma larinksa oba subregiona u poređenju sa pacijentima koji su imali hronični laringitis. Rad je pokazao da nivo ekspresije epitelijalne MMP-2 nije u korelaciji sa T, N ili kliničkim stadijumom bolesti i petogodišnjim preživljavanjem. Kod supraglotičnih karcinoma, MMP-2 je bila u korelaciji sa prisustvom perineuralne i limfovaskularne invazije. Uočena je i povezanost između epitelijalne MMP-2 ekspresije i pojave lokalnog recidiva karcinoma supraglotične lokalizacije. Takođe, nađena je negativna korelacija između histološkog stadijuma supraglotičnog karcinoma i nivoa ekspresije MMP-2. Što se tiče tumorskog rasta, otkrivena je statistička značajnost. MMP-2 ćelijska ekspresija je u direktoj korelaciji sa vegetativnim tumorskim rastom glotičnih karcinoma. Istraživanje nije otkrilo povezanost između epitelijalne MMP-9 ekspresije i nekih kliničkopatoloških karakteristika (T stadijum, N stadijum, klinički ili histološki stadijum) niti korelaciju sa DFI i petogodišnjim preživljavanjem. Epitelijalna MMP-9 ekspresija je u značajnoj korelaciji sa prisustvom limfovaskularne invazije i sa vegetantnim načinom rasta glotičnih tumora. Kod pacijenata sa karcinomom supraglotične lokalizacije, nisu nađeni slične relacije. Nije detektovana statistički značajna korelacija između ekspresije MMP-9 u epitelijalnim ćelijama i perineuralnom invazijom kod karcinoma larinksa. Ovo istraživanje je pokazalo visoku ekspresiju MMP-2 i MMP-9 i u epitelu i stromi pacijenata sa planocelularnim karcinomom u poređenju sa pacijentima sa hroničnim laringitisom. Naši rezultati ukazuju da bi MMP-2 ekspresija mogla poslužiti kao potencijalni parametar za otkrivanje pacijenata sa supraglotičnim karcinomom larinksa, koji su u visokom riziku za razvoj perineuralne i limfovaskularne invazije, odnosno razvoj lokalnog recidiva bolesti. MMP-9 ekspresija bi mogla biti prediktor vegetantnog načina tumorskog rasta i prisustva limfovaskularne invazije u karcinomu glotične sublokalizacije." ]
[ "Laryngeal malignant tumours consist about 1-2% of all malignant tumours in human population. Laryngeal squamous cell carcinoma (LSCC) is more common in male than in female population, occuring usually between the fifth and seventh decade of life. The most important etiological factors for LSCC are tobacco smoking, consumption of alcoholic drinks, gastroesophageal reflux, human papilloma virus (HPV) infections, air pollution, a diet low in fruits and vegetables. Prognosis of LSCC depends on the regional involvement of malignant disease, actual stage of disease, which can be determined by Tumour Node Metastasis (TNM) classification. Survival is significantly reduced due to the cancer development and spread of disease (local or regional recurrence and of distant metastasis occurrence). In recent years, molecular investigations have discovered many mechanisms of oncogenesis in malignant tumours. Expression of the specific tumour markers is associated with disease development and biological behavior of laryngeal carcinoma. Prognostic value identification of some tumour markers would be of great help in selecting treatment modalities, which is of crucial significance for prognosis of disease. Matrix metalloproteinases (MMPs) are family of 23 endopeptidases, structurally very similar proteolytic enzymes which have ability to degrade extracellular matrix components. Thus, MMPs play important role in tumour progression and metastasis. Elevated levels of MMPs can be detected in tumour tissue and serum of patients with advanced cancer. MMPs can be divided into 6 subgroups. MMP-2 and MMP-9 have ability to destroy the type IV collagen, which is a very important component of basement membrane. This is a key moment, which is necessary for tumour growth and distant metastasis. Some published papers showed that MMP-2 and MMP-9 may play important roles in progression of head and neck squamous cell carcinoma. Identification of patients with high risk for tumour development, the presence of subsequent locoregional tumour recurrence, as well as the existence of regional metastases are very important for prognosis of disease, as well as for the choose the best treatment modality. The purpose of the investigation was to evaluate the clinical significance of MMP-2 and MMP-9 expression in tissue samples of patients with LSCC, comparing glottic and supraglottic region of larynx. This study included a total of 140 patients, 70 with histologically verified LSCC and 70 with chronic laryngitis. Patients with malignant tumour were divided into groups with respect to: localization in larynx (supraglottic, glottic); TNM stage of disease (Т1/Т2, Т3/Т4, N0, N+, M0, M+); disease stage (I, II, II, IV); degree of tumour differentiation (good, moderate, poor); type of tumour growth (infiltrative, exophytic, mixed); development of loco-regional recurrence (with or without disease recurrence); the presence of perineural invasion (with or without of perineural invasion); lymphovascular invasion (with or without lymphovascular invasion) and 5-year survival (with or without 5-year survival). The patients diagnosed, treated and followed-up for a period of minimum 5 years between 2010 and 2017 for LSCC in Department of Otorhinolaryngology. The control group consisted of patients diagnosed and treated for chronic laryngitis in the same period. Pathological and immunohistochemical analyses of tissue specimens were performed at the Institute for Pathology by the same experienced pathologist. Criteria for inclusion in the study were histologically verified LSCC and histologically verified chronic inflammatory changes in laryngeal mucosa. Criteria for exclusion from the study were other malignant diseases, previous radiotherapy or chemotherapy, previously performed surgical treatment of laryngeal tumour. Then, systemic diseases affecting the larynx, laryngeal benign pseudotumours. The mean patients’ age was 59.41 (±7.1) years, range from 40–79 years. There were 60 (85.7%) male and 10 (14.3%) female patients. There were 45 (64.3%) patients with glottic SCC, mean age 59.7 (±6.8) years and 25 (35.7%) with supraglottic SCC, the mean age of 58.8 (±7.7). The majority of patients with glottic SCC were in T1/T2 stage, whereas the majority of supraglottic SCC patients were in T3/T4 stage. There is no significant difference regarding the 5-year survival between glottic and supraglottic SCC. Results revealed significantly higher MMP-2 and MMP-9 expression in both epithelium and stromal tissue specimens of patients with glottic and supraglottic SCC in comparison to patients with chronic laryngitis. Study showed that epithelial MMP-2 expression is not in correlation with T, N or clinical stage and 5-year survival. In supraglottic SCC, the MMP-2 epithelial expression was in correlation with the presence of perineural and lymphovascular invasion. It was noticed a correlation between the epithelial MMP-2 expression and local recurrences of the primary supraglottic cancer. Also, a negative significant correlation was recorded between the MMP-2 epithelial expression and histological stage in supraglottic SCC. According to the tumor growth pattern, it was demonstrated a statistical significance. The MMP-2 tumor cell expression was in correlation with the presence of exophytic type of tumour growth in glottic SCC. The present study revealed no correlation between the epithelial MMP-9 expression and some clinicopathological characteristics (T stage, N stage, clinical or histological stage) nor the correlation with diseasefree interval and 5-year survival. Epithelial MMP-9 expression significantly correlates with the presence of lymphovascular invasion and with the presence of exophytic type of the tumor growth in glottic SCC. In patients with supraglottic localization of SCC, there were no similar relationships. It was found no statistical relationship between the expression of MMP-9 in epithelial cells and perineural invasion in the laryngeal SCC. This study demonstrated higher expression of MMP-2 and MMP-9 in both epithelium and stroma of patients with LSCC in comparison to patients with chronic laryngitis. The results suggest that MMP-2 expression can serve as a potential parameter for detection of patients with supraglottic SCC who are at high risk for perineural and lymphovascular invasion and developing disease recurrence. MMP-9 expression can be a strong predictor for the presence of exophytic type of tumour growth, as well as for the presence of lymphovascular invasion in glottic SCC." ]
application/pdf
sr
Универзитет у Крагујевцу, Факултет медицинских наука
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Крагујевцу
[ "Larinks", "Planocelularni karcinom", "Imunohistohemija", "Matriks metaloproteinaze", "Biomarkeri" ]
[ "Larynx", "Squamous cell carcinoma", "Immunohistochemistry", "Matrix metalloproteinases", "Biomarkers" ]
[ "Ispitivanje prognostičke vrednosti ekspresije metaloproteinaza matriksa 2 i 9 kod bolesnika sa planocelularnim karcinomom grkljana" ]
[ "Investigation of the prognostic value of matrix 2 and 9 metalloproteinase expression in patients with laryngeal squamous cell carcinoma" ]
doctoralThesis
[ "BY-NC-ND" ]
Перић, Aлександар; Сотировић, Јелена; Стојановић, Јасмина; Вукомановић Ђурђевић, Бисерка; Рашић, Дејан; Испитивање прогностичке вредности експресије металопротеиназа матрикса 2 и 9 код болесника са планоцелуларним карциномом гркљана; Испитивање прогностичке вредности експресије металопротеиназа матрикса 2 и 9 код болесника са планоцелуларним карциномом гркљана;
[ "https://nardus.mpn.gov.rs/bitstream/id/77112/Doctoral_thesis_11574.pdf", "https://nardus.mpn.gov.rs/bitstream/id/77329/bitstream_77329.pdf", "https://fedorakg.kg.ac.rs/fedora/get/o:1397/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_18659" ]
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https://nardus.mpn.gov.rs/handle/123456789/17747
123456789-17747.pdf
yes
no
https://fedorakg.kg.ac.rs/fedora/get/o:1280/bdef:Content/download
no
Sociomedicinski aspekti depresivnosti kod starih u kontekstu savremenih demografskih i društveno-ekonomoskih odnosa
Sociomedical aspects of depression in the elderly in the contex of contemporary demographic and socio-economic relations
[ "Radević, Svetlana" ]
[ "Radovanović, Snežana", "Rančić, Nemanja", "Janjić, Vladimir" ]
Gajović, Gordana
2020-12-30T12:24:40
[ "2020-12-30T12:24:40" ]
2020-09-24
[ "http://eteze.kg.ac.rs/application/showtheses?thesesId=7717", "https://fedorakg.kg.ac.rs/fedora/get/o:1280/bdef:Content/download", "https://nardus.mpn.gov.rs/handle/123456789/17747" ]
[ "" ]
[ "" ]
application/pdf
sr
Универзитет у Крагујевцу, Факултет медицинских наука
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by/4.0/" ]
Универзитет у Крагујевцу
[ "depresija", "starenje stanovništva", "zdravstveni status" ]
[ "depression", "population aging", "health status" ]
[ "Sociomedicinski aspekti depresivnosti kod starih u kontekstu savremenih demografskih i društveno-ekonomoskih odnosa" ]
[ "Sociomedical aspects of depression in the elderly in the contex of contemporary demographic and socio-economic relations" ]
doctoralThesis
[ "BY" ]
Радевић, Светлана; Радовановић, Снежана; Ранчић, Немања; Јањић, Владимир; Гајовић, Гордана; Социомедицински аспекти депресивности код старих у контексту савремених демографских и друштвено-економоских односа; Социомедицински аспекти депресивности код старих у контексту савремених демографских и друштвено-економоских односа;
[ "https://nardus.mpn.gov.rs/bitstream/id/67638/Gordana_Gajovic_Medicina.pdf", "https://nardus.mpn.gov.rs/bitstream/id/67637/Disertacija.pdf", "https://fedorakg.kg.ac.rs/fedora/get/o:1280/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_17747" ]
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Uvod: Depresija je najčešći mentalni poremećaj kod osoba starije životne dobi sa ozbiljnim posledicama za pojedince, porodice i društvo u celini. Depresivni poremećaji u ovoj populaciji značajno narušavaju kvalitet života, fizičke, kognitivne i socijalne funkcije obolele osobe, povećavaju morbiditet i onesposobljenost, uzrokuju značajne socijalne i ekonomske posledice, pri čemu su u većoj meri pogođene osobe ženskog pola i nižeg socioekonomskog statusa. Depresija je takođe nezavisni prediktor mortaliteta i predstavlja vodeći uzrok samoubistava kod starih osoba. Cilj: Studija se bavi ispitivanjem učestalosti simptoma depresivnosti u populaciji stanovništva Srbije starosti 65 i više godina kao i ispitivanje povezanosti demografskih, socio-ekonomskih faktora i karakteristika zdravstvenog stanja sa prisustvom depresivnih simptoma. Materijal i metod: Istraživanje je urađeno po tipu studije preseka, masovnim anketiranjem slučajnog, reprezentativnog stratifikovanog dvoetapnog uzorka stanovništva Srbije 2013. godine, koje je realizovalo Ministarstva zdravlja Republike Srbije. Ciljnu populaciju je činilo ukupno 3540 ispitanika starosti 65 i više godina. Rezultati: Rezultati istraživanja ukazuju da postoji visoka prevalencija depresije kod starih. Na osnovu vrednosti PHQ-8 skora, ukupno 10% stanovništva Srbije starosti 65 i više godina je imalo depresivnu epizodu, dok je njih 17,5% imalo blage depresivne simptome. Posmatrano u odnosu na kategorije depresije, najveći broj starog stanovništva je imalo umerenu depresiju (5,8%), zatim sledi umereno teška depresija (2,6%), dok je najmanji procenat ispitanika imao tešku depresivnu epizodu (1,6%). Prevalencija depresije kontinuirano se povećava starošću, pa je prevalencija najveća u starosnoj grupi 85 i više godina (23,0%), kod osoba ženskog pola (12,7%), među osobama koje nikada nisu bile u braku ili vanbračnoj zajednici (18,6%), u vangradskim naseljima (12,5%), među osobama sa najnižim obrazovanjem (13,4%) i među najsiromašnijima (14,1%). Sve ispitivane demografske i socio-ekonomske varijable su se pokazale kao značajni prediktori prisustva depresije kod starijeg stanovništva. Veću verovatnoću da imaju depresiju imaju osobe ženskog pola (OR=1,67), osobe starosti 85 i više godina (OR=1,73), osobe koje nisu u braku (OR=2,023), sa najnižim nivoom obrazovanja (OR=2,41), nesposobne za rad (OR=4,2) i koje prema indeksu blagostanja pripadaju siromašnom sloju stanovništva (OR=1,61).
[ "" ]
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https://nardus.mpn.gov.rs/handle/123456789/8171
123456789-8171.pdf
no
no
http://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija145916315941126.pdf?controlNumber=(BISIS)100347&fileName=145916315941126.pdf&id=5167&source=NaRDuS&language=sr
no
Syntactic strategies behind free relatives
Sintaksa,dopunskenominalneklauze,paralelnospajanje
[ "Marković, Maja" ]
[ "Halupka-Rešetar, Sabina", "Mišić-Ilić, Biljana" ]
Милићевић, Наташа
2017-05-31T12:23:33
[ "2017-05-31T12:23:33", "2020-07-03T14:23:34" ]
2016-09-12
[ "http://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija145916315941126.pdf?controlNumber=(BISIS)100347&fileName=145916315941126.pdf&id=5167&source=NaRDuS&language=sr", "https://nardus.mpn.gov.rs/handle/123456789/8171", "http://www.cris.uns.ac.rs/record.jsf?recordId=100347&source=NaRDuS&language=sr", "http://www.cris.uns.ac.rs/DownloadFileServlet/IzvestajKomisije146373789448329.pdf?controlNumber=(BISIS)100347&fileName=146373789448329.pdf&id=5768&source=NaRDuS&language=sr" ]
[ "Tema ove teze je sintaksa dopunskih nominalnih klauza i neodređenih generalizirajućih zavisnih rečenica u engleskom i srpskom jeziku. Ovaj rad nudi zajedničku analizu niza fenomena koji su karakteristični za dopunske relativne klauze u engleskom i srpskom, u duhu pristupa zajedničkih struktura ili višestruke dominacije. Ovaj pristup pretpostavlja postojanje posebne vrste sintaksickog spajanja konstituenata, koje se naziva i kalemljenjem, a ovaj rad dokazuje njegovu validnost i emprijisku zasnovanost. Glavna teza ovog rada je da kalemljenje omogućava jednostavnije objašnjenje niza fenomena vezanih za karakterstike dopunskih nominalnih klauza u oba jezika. Što se tiče podataka iz srpskog jezika, ova teza pokazuje da je pogrešna uobičajena konstatacija o slobodnijoj distribuciji dopunskih nominalnih klauza u jezicima sa fonološki nerealizovanim subjektom, i nudi analizu činjenica koje su u tom pogledu relevantne. Ova teza takođe nudi analizu neodređenih generalizirajućih zavisnih klauza u srpskom jeziku tako što definiše tip konstrukicje koji se može smatrati ovom vrstom klauze, kao i meru u kojoj ona deli svojstva sa ovim tipom klauza u engleskom jeziku. Ovaj rad obrazlaže zašto je pomeranje predikata adekvatnija analiza ovih konstrukcija od analize poznate kao pitanje plus brisanje. Konačno, ovaj rad nudi zanimljivo zapažanje u vezi sa prirodom klauza koje imaju funkciju predikata u prostim rečenicama sa glagolom biti." ]
[ "The topic of this thesis is the syntax of free relative clauses and specificational pseudoclefts, with the focus on English and Serbian. It offers a unifying analysis for the range of phenomena related to the syntax of free relative clauses in English and Serbian, within a structure sharing, or multi-dominance approach. This approach assumes the existence of a particular type of displacement in syntax, which is referred to as grafting, and argues for its validity on theoretical and empirical ground. It is argued in this thesis that grafting enables a more parsimonious account of a range of phenomena related to the properties of free relatives in both languages. As far as the Serbian data is concerned, it has been shown that the common observation about a less constrained 8 distribution of FRs in langugages with null subjects is wrong, and the analysis of the relevant data is provided. This thesis also provides an account of specificational pseudoclefts in Serbian – determining what counts as this type of construction and to what degree it matches the properties of English specificiational pseudoclefts. It has been argued that their derivation involves predicate raising and not the question-plus-deletion analysis. Finally, this work provides an important insight into the nature of clausal predicates inside copular constructions in English and Serbian the key properties that connect them." ]
en
Универзитет у Новом Саду, Филозофски факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Новом Саду
[ "Sintaksa", "dopunskenominalneklauze", "paralelnospajanje" ]
[ "Syntax", "Freerelativeclauses", "grafts" ]
[ "Syntactic strategies behind free relatives" ]
[ "Sintaksa,dopunskenominalneklauze,paralelnospajanje" ]
doctoralThesis
[ "BY-NC-ND" ]
Марковић, Маја; Халупка-Решетар, Сабина; Мишић-Илић, Биљана; Milićević, Nataša;
[ "https://nardus.mpn.gov.rs/bitstream/id/46061/Disertacija9386.pdf", "https://nardus.mpn.gov.rs/bitstream/id/46062/IzvestajKomisije9386.pdf", "http://nardus.mpn.gov.rs/bitstream/id/46061/Disertacija9386.pdf", "http://nardus.mpn.gov.rs/bitstream/id/46062/IzvestajKomisije9386.pdf", "http://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija145916315941126.pdf?controlNumber=(BISIS)100347&fileName=145916315941126.pdf&id=5167&source=NaRDuS&language=sr" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_8171" ]
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https://nardus.mpn.gov.rs/handle/123456789/1674
123456789-1674.pdf
yes
no
http://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija144222143534469.pdf?controlNumber=(BISIS)94890&fileName=144222143534469.pdf&id=4304&source=NaRDuS&language=sr
no
Модели управљања квалитетом ресторатерских услуга
Modeli upravljanja kvalitetom restoraterskih usluga
[ "Blešić, Ivana" ]
[ "Popov-Raljić, Jovanka", "Blešić, Ivana", "Hadžić, Olga", "Janićević, Sava", "Stefanović, Vidoje" ]
Ivkov, Milan
2015-12-29T11:16:27
[ "2015-12-29T11:16:27", "2020-07-03T13:42:28" ]
2015-07-23
[ "http://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija144222143534469.pdf?controlNumber=(BISIS)94890&fileName=144222143534469.pdf&id=4304&source=NaRDuS&language=sr", "https://nardus.mpn.gov.rs/handle/123456789/1674", "http://www.cris.uns.ac.rs/record.jsf?recordId=94890&source=NaRDuS&language=sr", "http://www.cris.uns.ac.rs/DownloadFileServlet/IzvestajKomisije143160285175398.pdf?controlNumber=(BISIS)94890&fileName=143160285175398.pdf&id=3697&source=NaRDuS&language=sr" ]
[ "Свакако да је квалитет један од пресудних диференцирајућих фактора, те се зато све већа пажња придаје његовом управљању. Квалитет представља кључни елемент вредности услуге на основу које се предузећа позиционирају на тржишту, обезбеђују веће тржишно учешће, веће приходе и доприносе задовољству особља и потрошача. Суштина оријентације ка квалитету ресторатерског производа или услуге, има смисла једино ако се уваже сви аспекти квалитета, односно уколико се активности базирају на систему управљања тоталним квалитетом. Највећа одговорност за управљање квалитетом свакако је на руководству угоститељског објекта. У раду су приказани најчешће коришћени модели за истраживање задовољства потрошача и квалитета услуге, а на појединим се базира и спроведено истраживање, те су они шире објашњени. Такође, приказана су истраживања која су за основ имала моделе SERVQUAL или DINESERV. Предмет изучавања докторске дисертације јесте квалитет услуга у ресторатерству, управљање квалитетом ресторатерског производа и задовољство потрошача, односно корисника ресторатерских услуга. Реч је о вези квалитета услуге и задовољства потрошача која настаје на основу активности руководства ресторана. Зато је предметом овог истраживања обухваћено испитивање свих учесника (менаџери, особље и гости ресторана) који утичу на квалитет, односно перцепцију квалитета услуге. Циљ овог рада је да се утврди постојање и интензитет јазова који се јављају у пословању угоститељских објеката. Идентификација пет јазова и увид у елементе на основу којих се јазови појављују, основ је квалитетне анализе пословања и усмеравања активности ка унапређењу квалитета услуге у ресторатерству.", "Svakako da je kvalitet jedan od presudnih diferencirajućih faktora, te se zato sve veća pažnja pridaje njegovom upravljanju. Kvalitet predstavlja ključni element vrednosti usluge na osnovu koje se preduzeća pozicioniraju na tržištu, obezbeđuju veće tržišno učešće, veće prihode i doprinose zadovoljstvu osoblja i potrošača. Suština orijentacije ka kvalitetu restoraterskog proizvoda ili usluge, ima smisla jedino ako se uvaže svi aspekti kvaliteta, odnosno ukoliko se aktivnosti baziraju na sistemu upravljanja totalnim kvalitetom. Najveća odgovornost za upravljanje kvalitetom svakako je na rukovodstvu ugostiteljskog objekta. U radu su prikazani najčešće korišćeni modeli za istraživanje zadovoljstva potrošača i kvaliteta usluge, a na pojedinim se bazira i sprovedeno istraživanje, te su oni šire objašnjeni. Takođe, prikazana su istraživanja koja su za osnov imala modele SERVQUAL ili DINESERV. Predmet izučavanja doktorske disertacije jeste kvalitet usluga u restoraterstvu, upravljanje kvalitetom restoraterskog proizvoda i zadovoljstvo potrošača, odnosno korisnika restoraterskih usluga. Reč je o vezi kvaliteta usluge i zadovoljstva potrošača koja nastaje na osnovu aktivnosti rukovodstva restorana. Zato je predmetom ovog istraživanja obuhvaćeno ispitivanje svih učesnika (menadžeri, osoblje i gosti restorana) koji utiču na kvalitet, odnosno percepciju kvaliteta usluge. Cilj ovog rada je da se utvrdi postojanje i intenzitet jazova koji se javljaju u poslovanju ugostiteljskih objekata. Identifikacija pet jazova i uvid u elemente na osnovu kojih se jazovi pojavljuju, osnov je kvalitetne analize poslovanja i usmeravanja aktivnosti ka unapređenju kvaliteta usluge u restoraterstvu." ]
[ "Quality is one of the key differentiating factors, and therefore, more attention is given to its management. It is a key element of the service value that company uses to position itself in the market, providing greater market share, higher revenues and contribute to the satisfaction of staff and customers. The orientation towards quality of restaurant product or service makes sense only if are taken into consideration all aspects of quality, and if the activities are based on a system of total quality management. The greatest responsibility for quality control is certainly on the management team of a restaurant. This paper presents the most commonly used models for the study of consumer satisfaction and service quality. Some models are the base of conducted research, and they are explained in more detail. Also, the thesis presents studies based on SERVQUAL or DINESERV model. Subject of this dissertation is service quality in restaurant industry, quality management and customer satisfaction. It is about the relationship of service quality and customer satisfaction that arises from management activities. For that reason, this study included the examination of all participants (managers, staff and restaurant guests) that affect the quality and perception of service quality. The aim of this study was to determine the existence and intensity of the gaps that occur in the restaurant business. Identification of five gaps and insight into the elements that initiate the gap appearance, is the basis of a thorough analysis of business activities towards improvement of the quality of services in restaurant industry." ]
sr (cyrillic script)
Универзитет у Новом Саду, Природно-математички факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by/4.0/" ]
Универзитет у Новом Саду
[ "Менаџмент", "Menadžment", "квалитет услуге", "ресторатерство", "очекивање и задовољство потрошача", "kvalitet usluge", "restoraterstvo", "očekivanje i zadovoljstvo potrošača" ]
[ "Мanagement", "service quality", "restaurant industry", "customers‟ expectations and satisfaction" ]
[ "Модели управљања квалитетом ресторатерских услуга", "Modeli upravljanja kvalitetom restoraterskih usluga", "Models for quality management in the restaurant industry." ]
[ "" ]
doctoralThesis
[ "BY" ]
Блешић Ивана; Блешић Ивана; Стефановић Видоје; Попов-Раљић Јованка; Хаджић Олга; Јанићевић Сава; Ивков Милан; Modeli upravljanja kvalitetom restoraterskih usluga; Модели управљања квалитетом ресторатерских услуга; Модели управљања квалитетом ресторатерских услуга;
[ "https://nardus.mpn.gov.rs/bitstream/id/37949/IzvestajKomisije.pdf", "http://nardus.mpn.gov.rs/bitstream/id/37949/IzvestajKomisije.pdf", "http://nardus.mpn.gov.rs/bitstream/id/37948/Disertacija.pdf", "https://nardus.mpn.gov.rs/bitstream/id/37948/Disertacija.pdf", "http://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija144222143534469.pdf?controlNumber=(BISIS)94890&fileName=144222143534469.pdf&id=4304&source=NaRDuS&language=sr" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_1674" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
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https://nardus.mpn.gov.rs/handle/123456789/1673
123456789-1673.pdf
yes
no
http://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija144307787321372.pdf?controlNumber=(BISIS)94954&fileName=144307787321372.pdf&id=4345&source=NaRDuS&language=sr
no
Predviđanje trodimenzionalne strukture i karakterizacija aktivnog mesta odabranih beta-galatkozidaza
Prediction of trodimensional structure and characterisation of active sites of selected beta-galaktosidases
[ "Petri, Edward" ]
[ "Milanović, Spasenija", "Kojić, Danijela", "Ćelić, Anđelka", "Petri, Edward" ]
Vukić, Vladimir
2015-12-29T11:16:26
[ "2015-12-29T11:16:26", "2020-07-03T13:42:27" ]
2015-08-25
[ "http://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija144307787321372.pdf?controlNumber=(BISIS)94954&fileName=144307787321372.pdf&id=4345&source=NaRDuS&language=sr", "https://nardus.mpn.gov.rs/handle/123456789/1673", "http://www.cris.uns.ac.rs/record.jsf?recordId=94954&source=NaRDuS&language=sr", "http://www.cris.uns.ac.rs/DownloadFileServlet/IzvestajKomisije143272692151417.pdf?controlNumber=(BISIS)94954&fileName=143272692151417.pdf&id=3762&source=NaRDuS&language=sr" ]
[ "Proteini imaju osnovnu ulogu u životnim procesima, usled čega je isptivanje raznovrsnosti njihove strukture jedna od ključnih potreba modernih bioloških istraživanja. Cilj ove doktorske disertacije je predviđanje trodimenzionalne strukture beta-galaktozidaza odabranih bakterijskih sojeva (Streptococcus thermophillus, Lactobacillus acidophilus, i Bifidobacterium animalis ssp. lactis) kao i karakterizacija njihovih aktivnih mesta i određivanje aktivnih rezdua. Takođe, cilj disertacije obuhvata i ispitivanje beta-galaktozidaze Bacteroides thetaiotaomicron-a, kao i ispitivanje aktivnosti beta-galaktozidaze Kluyveromyces lactis-a. Na osnovu sličnosti analizirane sekvence se mogu podeliti u dva klastera. Članovi klastera 1 pripadaju GH-2 subfamiliji, dok članovi klastera 2 pripadaju GH-42 subfamiliji. Na osnovu klaster analize i poravnanja sekvenci predložene su katalitički aktivne rezidue beta-galaktozidaza ispitivanih sojeva: GLU458/GLU546 kod S. thermophillus-a, GLU148/GLU307 kod L. Acidophilus-a i GLU164/GLU324 kod B. animalis ssp. lactis-a. Konstruisani su homologi modeli beta-galaktozidaza S. thermophilus, L. acidophilus, B. animalis ssp. lactis. Iz rezultata simulacije molekularnog dokinga svih beta-galaktozidaza uočljivo je da se supstrat veže za aktivno mesto koje se nalazi u regionu visoke elektronegativnosti. Simulacije dokinga su potvrdile aktivna mesta predložena poravnanjem sekvenci i otkrile rezidue koje učestvuju u vezivanju laktoze i galaktoze kao supstrata. Obzirom da je objavljena samo jedna kristalna struktura beta-galaktozidaze sa laktozom u aktivnom mestu, analiza molekularnog dokinga laktoze kao supstrata je sprovedena i sa beta-alaktozidazama koje imaju određenu trodimenzionalnu strukturu. Na osnovu slučnosti sekvenci može se zaključiti da je nukleofilna rezidua beta-galaktozidaze B. thetaiotaomicron-a GLU259. Analizom konzervativnih regiona, kao i doking simulacije, može se zaključiti da ulogu proton donora ima rezidua GLU182. Hemijski sastav mleka za ispitivanje aktivnosti beta-galaktozidaze Kluyveromyces lactis-a je u skladu sa pravilnikom o kvalitetu proizvoda od mleka i starter kultura koji izdaje Ministarstvo poljoprivrede i zaštite životne sredine Republike Srbije. Celokupna laktoza se razgradila u permeatu na temperaturi od 40°C i pri koncentraciji enzima od 0,1% nakon 60 minuta od trenutka dodatka enzima. Maksimalna brzina postiže se toku prvih 10 minuta. Iz dobijenih rezultata može se zaključiti da beta-galaktozidaza K. lactis-a ima visoku efikasnost prilikom razgradnje laktoze što je čini pogodnom za komercijalnu upotrebu u industriji mleka. U ovoj disertaciji predstavljen je protokol za modelovanje komercijalno važnih beta-galaktozidaza i analiziranje njihovih interakcija sa laktozom kao supstratom. Dobijeni rezultati treba da pruže okvir za molekularna istraživanja vezivanja i razgradnje laktoze, kao i za buduće dizajniranje komercijalno interesantnih beta-galaktzidaza." ]
[ "Proteins have an essential role in all life processes. Therefore, investigation of their structure diversity is one of the key focuses of modern biological researches. The aim of this PhD thesis is prediction of three-dimensional structure of beta-galactosidases of selected bacterial strains (Streptococcus thermophillus, Lactobacillus acidophilus and Bifidobacterium animalis ssp. lactis), as well as characterization of their active sites and active residues. Furthermore, this thesis include investigation Bacteroides thetaiotaomicron and Kluyveromyces lactis beta-galactosidases. Based on sequence similarity analyzed sequences can be clustered in two clusters. Members of cluster 1 belong to GH-2 subfamily, while members of cluster 2 belong to GH-42 subfamily. Cluster analysis and sequence alignment revealed potential active residues: GLU458/GLU546 - S. thermophillus, GLU148/GLU307 - L. Acidophilus and GLU164/GLU324 - B. animalis ssp. lactis. Homologous models of beta-galactosidases from S. thermophilus, L. acidophilus, B. animalis ssp. lactis are constructed as a result of this PhD thesis. Molecular docking simulations of all beta-galactosidases revealed that substrate binds in region with high electronegativity. Furthermore, docking simulations confirmed active sites suggested by sequence alignment. As only one crystal structure with lactose in its active site has been published, docking simulations with lactose as a ligand were also performed with experimentally determined beta-galactosidases structures. Also, lactose and alactose binding residues are predicted. Based on sequence similarity GLU259 can be recognized as nucleophile of B. thetaiotaomicron beta-galactosidase. By analysis of conserved regions and docking simulation, GLU182 is predicted as a proton donor residue. Chemical composition of milk used for Kluyveromyces lactis beta-galactosidase research had appropriate quality according to directions of Ministry of agriculture and environmental protection of Republic of Serbia. Total lactose content was degraded in permeate after 60 min using enzyme concentration of 0,1% at 40°C. Maximal degradation was reached in the first 10 min. Based on the results, it can be concluded that Kluyveromyces lactis beta-galactosidase has high efficiency for lactose degradation, which makes it commercially interesting for milk industry. Protocol for modeling of commercially important beta-galactosidases and their interactions with lactose is developed as a result of this PhD thesis. Obtained results should provide the frame for molecular investigation of lactose binding and degradation, as well as for designing of commercially suitable beta-galactozidases." ]
sr (latin script)
Универзитет у Новом Саду, Природно-математички факултет
[ "info:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/46009/RS//" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc/4.0/" ]
Универзитет у Новом Саду
[ "Beta-galaktozidaza", "predviđanje strukture", "molekularni doking", "probiotici", "tehnologija mleka" ]
[ "" ]
[ "Predviđanje trodimenzionalne strukture i karakterizacija aktivnog mesta odabranih beta-galatkozidaza", "Prediction of trodimensional structure and characterisation of active sites of selected beta-galaktosidases" ]
[ "" ]
doctoralThesis
[ "BY-NC" ]
Петри Едwард; Петри Едwард; Ћелић Aнђелка; Милановић Спасенија; Којић Данијела; Вукић Владимир; Предвиђање тродимензионалне структуре и карактеризација активног места одабраних бета-галаткозидаза; Предвиђање тродимензионалне структуре и карактеризација активног места одабраних бета-галаткозидаза;
[ "https://nardus.mpn.gov.rs/bitstream/id/37941/Disertacija.pdf", "https://nardus.mpn.gov.rs/bitstream/id/37942/IzvestajKomisije.pdf", "http://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija144307787321372.pdf?controlNumber=(BISIS)94954&fileName=144307787321372.pdf&id=4345&source=NaRDuS&language=sr" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_1673" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
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https://nardus.mpn.gov.rs/handle/123456789/1680
123456789-1680.pdf
yes
no
http://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija144612576421397.pdf?controlNumber=(BISIS)95018&fileName=144612576421397.pdf&id=4508&source=NaRDuS&language=sr
no
Музеји у функцији културног туризма Војводине
Muzeji u funkciji kulturnog turizma Vojvodine
[ "Pivac, Tatjana" ]
[ "Hadžić, Olga", "Pivac, Tatjana", "Besermenji, Snežana", "Jovičić, Dobrica" ]
Medić, Sandra
2015-12-29T11:16:36
[ "2015-12-29T11:16:36", "2020-07-03T13:42:38" ]
2015-09-29
[ "https://nardus.mpn.gov.rs/handle/123456789/1680", "http://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija144612576421397.pdf?controlNumber=(BISIS)95018&fileName=144612576421397.pdf&id=4508&source=NaRDuS&language=sr", "http://www.cris.uns.ac.rs/record.jsf?recordId=95018&source=NaRDuS&language=sr", "http://www.cris.uns.ac.rs/DownloadFileServlet/IzvestajKomisije143351192938653.pdf?controlNumber=(BISIS)95018&fileName=143351192938653.pdf&id=3802&source=NaRDuS&language=sr" ]
[ "Истраживање спроведено у музејима на подручју Војводине имало је за циљ да утврди положај који музеји имају у туристичкој понуди, однос интерних стејкхолдера према туризму, као и мотивисаност посетилаца за посету музејима и њихово задовољство понудом. Резултати су показали да интеррни стејкхолдери имају позитиван став према туризму и туристима, те да се музејско пословање променило у односу на претходне године у смислу већег освртања на туризам и потребе туриста. Такође, показано је да су одређене социо-демографске карактеристике и осећања испитаника, појединачни мотивацијски фактори и фактори задовољства значајни предиктори општег задовољства испитаника посетом. На основу теренског истраживања и добијених емпиријских резултата дати су предлози за унапређење музејске понуде, односно, за интензивније укључивање музеја у понуду културног туризма на подручју Војводине", "Istraživanje sprovedeno u muzejima na području Vojvodine imalo je za cilj da utvrdi položaj koji muzeji imaju u turističkoj ponudi, odnos internih stejkholdera prema turizmu, kao i motivisanost posetilaca za posetu muzejima i njihovo zadovoljstvo ponudom. Rezultati su pokazali da interrni stejkholderi imaju pozitivan stav prema turizmu i turistima, te da se muzejsko poslovanje promenilo u odnosu na prethodne godine u smislu većeg osvrtanja na turizam i potrebe turista. Takođe, pokazano je da su određene socio-demografske karakteristike i osećanja ispitanika, pojedinačni motivacijski faktori i faktori zadovoljstva značajni prediktori opšteg zadovoljstva ispitanika posetom. Na osnovu terenskog istraživanja i dobijenih empirijskih rezultata dati su predlozi za unapređenje muzejske ponude, odnosno, za intenzivnije uključivanje muzeja u ponudu kulturnog turizma na području Vojvodine" ]
[ "The aim of the study conducted in Vojvodina's museums was to identify the role of museums in a tourism offer, internal stakeholders' perception towards tourism, visitors' motivation and satisfaction. The results showed internal stakeholders' positive perception towards tourism and tourists and that the museum practice, based on consideration given to tourism and tourists' needs, is changed over time. Also, it is shown that certain socio-demographic characteristics of respondents, their feeelings about the experience at the museum, certain motivational and satisfaction factors are significant predictors of overall satisfaction of museum visitors. According to field research and the empirical results the suggestions are made in order to improve museum and include them more effectively in cultural tourism offer in Vojvodina." ]
sr (cyrillic script)
Универзитет у Новом Саду, Природно-математички факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Новом Саду
[ "Културни туризам", "Kulturni turizam", "музеји", "мотивација посетилаца", "задовољство посетилаца", "Војводина", "muzeji", "motivacija posetilaca", "zadovoljstvo posetilaca", "Vojvodina" ]
[ "cultural tourism", "museums", "motivation", "satisfaction", "Vojvodina" ]
[ "Музеји у функцији културног туризма Војводине", "Muzeji u funkciji kulturnog turizma Vojvodine", "Museums’ Role in Cultural Tourism of Vojvodina" ]
[ "" ]
doctoralThesis
[ "BY-NC-ND" ]
Пивац Татјана; Хаджић Олга; Бесермењи Снежана; Пивац Татјана; Јовичић Добрица; Медић Сандра; Музеји у функцији културног туризма Војводине; Музеји у функцији културног туризма Војводине; Muzeji u funkciji kulturnog turizma Vojvodine;
[ "http://nardus.mpn.gov.rs/bitstream/id/37990/Disertacija.pdf", "http://nardus.mpn.gov.rs/bitstream/id/37991/IzvestajKomisije.pdf", "https://nardus.mpn.gov.rs/bitstream/id/37990/Disertacija.pdf", "https://nardus.mpn.gov.rs/bitstream/id/37991/IzvestajKomisije.pdf", "http://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija144612576421397.pdf?controlNumber=(BISIS)95018&fileName=144612576421397.pdf&id=4508&source=NaRDuS&language=sr" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_1680" ]
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https://nardus.mpn.gov.rs/handle/123456789/1679
123456789-1679.pdf
no
no
http://nardus.mpn.gov.rs/bitstream/id/37983/Disertacija.pdf
no
Extendable and Adaptable Framework for Input Language Independent Static Analysis
Proširiv i prilagodljiv okvir za statičku analizu nezavisnu od ulaznog jezika
[ "Budimac, Zoran" ]
[ "Kurbalija, Vladimir", "Budimac, Zoran", "Ivanović, Mirjana", "Heričko, Marjan" ]
Rakić, Gordana
2015-12-29T11:16:30
[ "2015-12-29T11:16:30", "2020-07-03T13:42:36" ]
2015-09-16
[ "http://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija14436923075638.pdf?controlNumber=(BISIS)95005&fileName=14436923075638.pdf&id=4382&source=NaRDuS&language=sr", "https://nardus.mpn.gov.rs/handle/123456789/1679", "http://www.cris.uns.ac.rs/record.jsf?recordId=95005&source=NaRDuS&language=sr", "http://www.cris.uns.ac.rs/DownloadFileServlet/IzvestajKomisije143332963104455.pdf?controlNumber=(BISIS)95005&fileName=143332963104455.pdf&id=3788&source=NaRDuS&language=sr" ]
[ "U modernim pristupima razvoju softvera veliki značaj pridaje se kontroli kvaliteta softvera u ranim fazama razvoja. Zbog toga, statička analiza postaje sve značajnija. Takođe, softverski proizvodi postaju sve kompleksniji i heterogeni. Ove karakteristike se ogledaju u raznovrsnosti jezika i tehnologija koje se koriste u procesu razvoja softvera. Zbog toga, konzistentnost u statičkoj analizi dobija veći značaj nego što je to bio slučaj ranije. U ovoj disertaciji opisan je SSQSA skup statičkih analizatora za kontrolu kvaliteta (eng. Set of Software Quality Static Analyzers). Namena SSQSA okvira je konzistentna statička analiza. Cilj se postiže uvođenjem nove međureprezentacije izvornog koda nazvane eCST (obogaćeno konkretno sintaksno stablo, eng. enriched Concrete Syntax Tree). Fokus disertacije je primarno na eCST reprezenataciji koda, reprezentacijama izvedenjim iz eCST i procesu njihovog generisanja, sa opisom oruđa angažovanim u ovim procesima. Osnovna i najbitnija karakteristika eCST reprezenatacije je nezavisnost od jezika u kom je izvorni kod pisan, što SSQSA okviru daje proširivost na dva nivoa: kroz podršku za nove jezike i kroz podršku za nove analize. Ovo dovodi do efikasnog uvođenja funkcionalnosti na oba navedena nivoa, kao i do konzistentnosti uvedenih funkcionalnosti. Kao dokaz ispravnosti koncepta, podrška za više od 10 ulaznih jezika je uvedena. Takođe, implementirane su karakteristične tehnike statičke analize (izračunavanje softverskih metrika, otkrivanje duplikata u kodu, itd.) i integrisane u SSQSA okvir. Na opisani način, postavljanjem SSQSA okvira, obezbeđena je infrastruktura za dalji razvoj kompletne platforme za kontrolu kvaliteta softvera." ]
[ "In modern approach to software development, a great importance is given to monitoring of software quality in early development phases. Therefore, static analysis becomes more important. Furthermore, software projects are becoming more complex and heterogeneous. These characteristics are reflected in a diversity of functionalities and variety of computer languages and the technologies used for their development. Because of that consistency in static analysis becomes more important than it was earlier. In this dissertation SSQSA: Set of Software Quality Static Analyzers is described. The aim of the SSQSA framework is consistent static analysis. This goal is reached by introducing new intermediate source code representation called eCST: enriched Concrete Syntax Tree. The dissertation mostly focuses on eCST, intermediate representations derived from it, and their generation with description of the tools involved in it. The main characteristic of eCST is language independence which gives to SSQSA framework two-level extensibility: supporting a new language and supporting a new analysis. This leads to eciency of adding both level supports and consistency of added functionalities. To prove the concept, support for more than 10 characteristic languages was introduced. Furthermore, characteristic static analysis techniques (software metrics calculation, code-clone detection, etc.) were implemented and integrated in the framework. Established SSQSA framework provides the infrastructure for the further development of the complete platform for software quality control." ]
en
Универзитет у Новом Саду, Природно-математички факултет
[ "info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/174023/RS//" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc/4.0/" ]
Универзитет у Новом Саду
[ "kvalitet softvera", "statička analiza", "međureprezentacija" ]
[ "software quality", "static analysis", "intermediate representation" ]
[ "Extendable and Adaptable Framework for Input Language Independent Static Analysis", "Proširiv i prilagodljiv okvir za statičku analizu nezavisnu od ulaznog jezika" ]
[ "" ]
doctoralThesis
[ "BY-NC" ]
Будимац Зоран; Курбалија Владимир; Будимац Зоран; Херичко Марјан; Ивановић Мирјана; Ракић Гордана; Проширив и прилагодљив оквир за статичку анализу независну од улазног језика; Проширив и прилагодљив оквир за статичку анализу независну од улазног језика;
[ "http://nardus.mpn.gov.rs/bitstream/id/37984/IzvestajKomisije.pdf", "https://nardus.mpn.gov.rs/bitstream/id/37983/Disertacija.pdf", "https://nardus.mpn.gov.rs/bitstream/id/37984/IzvestajKomisije.pdf", "http://nardus.mpn.gov.rs/bitstream/id/37983/Disertacija.pdf", "http://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija14436923075638.pdf?controlNumber=(BISIS)95005&fileName=14436923075638.pdf&id=4382&source=NaRDuS&language=sr" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_1679" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/11374
123456789-11374.pdf
yes
no
https://nardus.mpn.gov.rs/bitstream/id/33271/Disertacija.pdf
no
Model višekriterijumske analize stručnih kompetencija studenta zasnovanih na informacionim tehnologijama
Multicriteria analysis model forprofessional competences of student basedon information technology
[ "Stojanov, Željko" ]
[ "Radosav, Dragica", "Mandić, Danimir", "Brtka, Vladimir", "Dobrilović, Dalibor", "Stojanov, Željko" ]
Jauševac, Goran
2019-09-27T10:51:35
[ "2019-09-27T10:51:35", "2020-07-03T13:16:35" ]
2018-09-28
[ "https://nardus.mpn.gov.rs/handle/123456789/11374", "https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija153147215778498.pdf?controlNumber=(BISIS)107568&fileName=153147215778498.pdf&id=11703&source=NaRDuS&language=sr", "https://www.cris.uns.ac.rs/record.jsf?recordId=107568&source=NaRDuS&language=sr", "https://www.cris.uns.ac.rs/DownloadFileServlet/IzvestajKomisije15311388760214.pdf?controlNumber=(BISIS)107568&fileName=15311388760214.pdf&id=11651&source=NaRDuS&language=sr" ]
[ "Disertacije se bavi problematikom identifikovanja stručnih kompetencija zasnovnaih na informacionim tehnologijama i načinom implementacije istih u postojeće nastavne planove i programe. U okviru disertacije je dizajniran model višekriterijumeske analize stručnih kompetencija studenta zasnovnih na informacionim tehnologijama. Model se sastoji iz tri modula: Modul za identifikacju stručnih kompetencija, Modul za rangiranje stručnih komepetencija i Modul za preporuku stručnih komepetencija. Identifikacija stručnih kompetencija vrši se iz različitih izvora kako bi dobili što potpuniju sliku šta je to potrebno od stručnih kompetencija zasnovnih na informacionimtehnologijama u profesionalnoj praksi. Uokviru modula za rangiranje uz pomoćvišekriterijumaske - višeekspertne analize vrši se rangiranje identifikovanih stručnihkompetencija. Modul za preporuke stručnih kompetencija uz pomoć komparativneanalize rangiranih stručnih kompetencija definiše preporuke za izmjene nastavnihplanova i programa prema potrebama profesionalne prakse. Model jeimplementiran na studijskom programuTelekomunikacije i poštanski saobraćaj naSaobraćajnom fakultetu u Doboju,Univerzitet u Istočnom Sarajevu, Bosna iHercegovina. Model definisan na ovakavnačin pomaže u poboljšanju kvaliteta kao i približavanju prakse Nastavnim planovima iprogramima." ]
[ "The dissertation deals with the problem of identifying professional competences based on information technologies, and with they implementation in existing curricula. A multicriteria analysis model for ranking professional competences of student based on information technology is formed. The Model consists of three modules: Module for identification of professional competences based on information technologies, Module for ranking professional competences and Module for the recommendation of professional cometences. Identification of professional competencies is done from different sources in order to get more complete picture which professional competences are needed in professional practice. Identified professional competencies are ranked within the ranking module by using multi-criteriamulti- expert analysis. The module for the recommendations of professional competences by using comparative analysis method proposes recommendations for changes in curricula based on the needs of professional practice. The model was implemented at the study program Telecommunications and Postal Traffic at the Faculty of Traffic Engineering in Doboj, University of East Sarajevo, Bosnia and Hercegovina. The model helps in improving quality as well as bringing professional practice closer to teaching plans and programs." ]
sr (latin script)
Универзитет у Новом Саду, Технички факултет Михајло Пупин, Зрењанин
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Новом Саду
[ "Upravljenje znajem", "Struče kompetencije", "Ishodi učenja", "Višekriterijumska analiza" ]
[ "Knowledge Management", "Professionalcompetencies", "Learning outcomes", "Multicriteriadecision analysis" ]
[ "Model višekriterijumske analize stručnih kompetencija studenta zasnovanih na informacionim tehnologijama" ]
[ "Multicriteria analysis model forprofessional competences of student basedon information technology" ]
doctoralThesis
[ "BY-NC-ND" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/33272/IzvestajKomisije.pdf", "http://nardus.mpn.gov.rs/bitstream/id/33271/Disertacija.pdf", "https://nardus.mpn.gov.rs/bitstream/id/33272/IzvestajKomisije.pdf", "https://nardus.mpn.gov.rs/bitstream/id/33271/Disertacija.pdf", "https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija153147215778498.pdf?controlNumber=(BISIS)107568&fileName=153147215778498.pdf&id=11703&source=NaRDuS&language=sr" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_11374" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
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https://nardus.mpn.gov.rs/handle/123456789/8703
123456789-8703.pdf
yes
no
http://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija146424584474816.pdf?controlNumber=(BISIS)101069&fileName=146424584474816.pdf&id=5815&source=NaRDuS&language=sr
no
Допринос интегрисаног модела управљања моторним возилима на крају животног циклуса развоју Републике Србије
Doprinos integrisanog modela upravljanja motornim vozilima na kraju životnog ciklusa razvoju Republike Srbije
[ "Sajfert, Zvonko" ]
[ "Đorđević, Dejan", "Arsovski, Slavko", "Nikolić, Milan", "Vujić, Goran", "Sajfert, Zvonko" ]
Павловић, Александар
2017-10-30T14:38:03
[ "2017-10-30T14:38:03", "2020-07-03T13:16:22" ]
2016-09-29
[ "https://nardus.mpn.gov.rs/handle/123456789/8703", "http://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija146424584474816.pdf?controlNumber=(BISIS)101069&fileName=146424584474816.pdf&id=5815&source=NaRDuS&language=sr", "http://www.cris.uns.ac.rs/record.jsf?recordId=101069&source=NaRDuS&language=sr", "http://www.cris.uns.ac.rs/DownloadFileServlet/IzvestajKomisije146424585694259.pdf?controlNumber=(BISIS)101069&fileName=146424585694259.pdf&id=5816&source=NaRDuS&language=sr" ]
[ "Полазећи од анализе рециклаже ELV у Србији и свету, анализиран је аспект одрживости и дефинисан модел одрживе рециклаже ELV. Применом fuzzy вишекритеријумског приступа, статистичких метода, Delphy методе и симулационих метода утврђени су кључни фактори успеха одрживости рециклаже ELV. Применом fuzzy приступа и симулационих динамичких модела за област рециклаже ELV, утврђен је утицај фактора одрживости рециклаже ELV на: (1) ниво рециклаже, (2) процес рециклаже у Србији и (3) одрживи развој Србије.", "Polazeći od analize reciklaže ELV u Srbiji i svetu, analiziran je aspekt održivosti i definisan model održive reciklaže ELV. Primenom fuzzy višekriterijumskog pristupa, statističkih metoda, Delphy metode i simulacionih metoda utvrđeni su ključni faktori uspeha održivosti reciklaže ELV. Primenom fuzzy pristupa i simulacionih dinamičkih modela za oblast reciklaže ELV, utvrđen je uticaj faktora održivosti reciklaže ELV na: (1) nivo reciklaže, (2) proces reciklaže u Srbiji i (3) održivi razvoj Srbije." ]
[ "Starting from the analysis of the ELV recycling in Serbia and the world, the aspect of sustainability and sustainable model defined ELV recycling is analyzed. Application of fuzzy multi-criteria approach, statistical methods, Delphy methods and simulation methods identified are key success factors in the sustainability of ELV recycling. By application of fuzzy approach and dynamic simulation models for the ELV recycling, influence of ELV recycling sustainability factors is determined on: (1) the level of recycling, (2) the recycling process in Serbia, and (3) the sustainable development of Serbia." ]
sr (cyrillic script)
Универзитет у Новом Саду, Технички факултет Михајло Пупин, Зрењанин
[ "info:eu-repo/grantAgreement/MESTD/Technological Development (TD or TR)/35033/RS//" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Новом Саду
[ "рециклажа", "reciklaža", "održivi razvoj", "motorna vozila na kraju životnog ciklusa (ELV)", "одрживи развој", "моторна возила на крају животног циклуса (ELV)" ]
[ "recycling", "sustainable development", "motor vehicles and end of life (ELV)" ]
[ "Допринос интегрисаног модела управљања моторним возилима на крају животног циклуса развоју Републике Србије" ]
[ "Doprinos integrisanog modela upravljanja motornim vozilima na kraju životnog ciklusa razvoju Republike Srbije" ]
doctoralThesis
[ "BY-NC-ND" ]
Сајферт, Звонко; Николић, Милан; Вујић, Горан; Сајферт, Звонко; Aрсовски, Славко; Ђорђевић, Дејан; Pavlović, Aleksandar; Doprinos integrisanog modela upravljanja motornim vozilima na kraju životnog ciklusa razvoju Republike Srbije;
[ "https://nardus.mpn.gov.rs/bitstream/id/33214/Disertacija13401.pdf", "https://nardus.mpn.gov.rs/bitstream/id/33215/IzvestajKomisije13401.pdf", "http://nardus.mpn.gov.rs/bitstream/id/33214/Disertacija13401.pdf", "http://nardus.mpn.gov.rs/bitstream/id/33215/IzvestajKomisije13401.pdf", "http://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija146424584474816.pdf?controlNumber=(BISIS)101069&fileName=146424584474816.pdf&id=5815&source=NaRDuS&language=sr" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_8703" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
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[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/8463
123456789-8463.pdf
yes
no
https://fedorani.ni.ac.rs/fedora/get/o:1384/bdef:Content/download
no
Franšizing kao strategija internacionalizacije malih i srednjih preduzeća
[ "Stefanović, Suzana" ]
[ "Milovanović, Goran", "Paunović, Blagoje" ]
Stanković, Milica S.
2017-07-28T14:36:39
[ "2017-07-28T14:36:39", "2020-07-03T16:01:01" ]
2017-06-15
[ "https://nardus.mpn.gov.rs/handle/123456789/8463", "http://eteze.ni.ac.rs/application/showtheses?thesesId=5138", "https://fedorani.ni.ac.rs/fedora/get/o:1384/bdef:Content/download", "http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70052&RID=533898646" ]
[ "" ]
[ "The internationalization is an important strategy for small and medium enterprises (SMEs) that want to expand their business in foreign markets. Franchising, as a strategy of internationalization of SMEs, is still insufficiently researched topic, especially in the Republic of Serbia. Therefore, the main aim of the research is ТНОntТПТМatТon oП tСО sТtuatТon anН opportunТtТОs Пor SMEs’ internationalization and the implementation of franchising as one of the internationalization strategies. After defining the theoretical framework, the empirical research was conducted, with the aim of contributing to the understanding and encouragement of franchising as the strategy of internationalization of SMEs in the Republic of Serbia. The empirical verification of defined hypothesis was performed by statistical analysis of primary data collected through on-line questionnaires. The implementation period of the field research was from May to July 2016. The research was focused on franchise SMEs in the Republic of Serbia. The realization of sample was 32 franchise SMEs. Hypothesis testing was conducted using a set of statistical methods. The research results indicate that franchise SMEs in the Republic of Serbia implement franchising less frequent than other internationalization strategies. In addition, the results show that internal and external factors, and factors from the domain of modern ICT and the Internet can have an impact on the implementation of franchising as a strategy of internationalization. In the final, the results indicate the existence of differences in the size and character of the impact of certain internal and external factors between the franchise SMEs which implement franchising and franchise SMEs which implement other strategies of internationalization. After analyzing the obtained results, the relevant recommendations are given in terms of raising awareness of SME owners about the benefits of franchising as a strategy of internationalization and promoting the franchising as a business concept. The practical implications of the research are related to the recommendations for greater institutional support for existing franchise SMEs and SMEs that are planning to develop its franchise system in the future." ]
application/pdf
sr
Универзитет у Нишу, Економски факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Нишу
[ "Franšizing", "mala i srednja preduzeća", "strategije internacionalizacije" ]
[ "franchising", "small and medium enterprises", "strategies of internationalization" ]
[ "Franšizing kao strategija internacionalizacije malih i srednjih preduzeća" ]
[ "" ]
doctoralThesis
[ "BY-NC-ND" ]
Стефановић, Сузана; Миловановић, Горан; Пауновић, Благоје; Станковић, Милица С.; Франшизинг као стратегија интернационализације малих и средњих предузећа; Франшизинг као стратегија интернационализације малих и средњих предузећа;
[ "https://nardus.mpn.gov.rs/bitstream/id/52014/Disertacija.pdf", "http://nardus.mpn.gov.rs/bitstream/id/52015/Stankovic_Milica_S.pdf", "https://nardus.mpn.gov.rs/bitstream/id/52015/Stankovic_Milica_S.pdf", "http://nardus.mpn.gov.rs/bitstream/id/52014/Disertacija.pdf", "https://fedorani.ni.ac.rs/fedora/get/o:1384/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_8463" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/6661
123456789-6661.pdf
yes
no
http://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija146642122029412.pdf?controlNumber=(BISIS)101272&fileName=146642122029412.pdf&id=6076&source=NaRDuS&language=sr
no
Uticaj soli žučnih kiselina na prodor i metabolizam simvastatina u probiotskim bakterijama
The influence of bile salts on simvastatin transport and metabolism in probiotic bacteria
[ "Mikov, Momir", "Suvajdžić, Ljiljana" ]
[ "Stankov, Karmen", "Stilinović, Nebojša", "Vukmirović, Saša", "Dobrić, Silva", "Vasović, Velibor" ]
Đanić, Maja
2016-10-08T15:47:48
[ "2016-10-08T15:47:48", "2020-07-03T13:27:29" ]
2016-09-15
[ "http://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija146642122029412.pdf?controlNumber=(BISIS)101272&fileName=146642122029412.pdf&id=6076&source=NaRDuS&language=sr", "https://nardus.mpn.gov.rs/handle/123456789/6661", "http://www.cris.uns.ac.rs/record.jsf?recordId=101272&source=NaRDuS&language=sr", "http://www.cris.uns.ac.rs/DownloadFileServlet/IzvestajKomisije14664212310669.pdf?controlNumber=(BISIS)101272&fileName=14664212310669.pdf&id=6077&source=NaRDuS&language=sr" ]
[ "Interindividualne razlike u sastavu i aktivnosti crevne mikroflore mogu uticati na metabolizam lekova kao i na njihov konačan terapijski odgovor. Simvastatin je lek iz grupe statina i karakteriše ga izuzetno mala rastvorljivost u vodi, mala bioraspoloživost (<5%) i velike interindividualne razlike u terapijskom odgovoru čiji uzroci nisu u potpunosti objašnjeni. Poslednjih godina velika pažnja se posvećuje ispitivanjima žučnih kiselina u razvoju novih farmaceutskih formulacija zbog svoje uloge u solubilizaciji i modifikaciji prodora lekova kroz biološke membrane. Zbog svega navedenog, u fokusu našeg istraživanja su bile potencijalne interakcije između simvastatina, probiotskih bakterija i žučnih kiselina o kojima se vrlo malo zna, a od izuzetne su važnosti, zbog mogućeg uticaja na farmakokinetske i farmakodinamske osobine simvastatina, pa samim tim i na konačan terapijski odgovor kod pacijenta.Cilj istraživanja je bio da se ispita prodor i metabolizam simvastatina u probiotskim bakterijama kao i uticaj različitih žučnih kiselina na transport ovog leka u bakterijske ćelije. Takođe, cilj je bio da se ispita uticaj soli žučnih kiselina na distribucioni koeficijent simvastatina, kao i interakcije žučnih kiselina sa simvastatinom na nivou transportnih proteina probiotskih bakterija kako bi se objasnila priroda očekivanih interakcija.Identifikacija i kvantifikacija uzoraka vršena je metodom tečne hromatografije sa masenom spektrometrijom (LC-MS/MS). Korišćenjem programskih paketa VolSurf+ i Molinspiration, za identifikovane metabolite su izračunati molekulski deskriptori koji opisuju fizičko-hemijske i farmakokinetske osobine molekula. Određivanje distribucionog koeficijenta vršeno je Shake-flask metodom. Interakcije žučnih kiselina sa simvastatinom na nivou transportnih proteina probiotskih bakterija ispitane su doking studijama pomoću SwissDock programa. Prilikom dvadesetčetvoročasovne inkubacije sa probiotskim bakterijama uočen je statistički značajan pad koncentracije simvastatina u ekstracelularnom sadržaju. Ukupan sadržaj simvastatina, kao zbir ekstracelulamog i intracelularnog sadržaja, je tokom čitavog ispitivanog perioda bio statistički značajno niži u odnosu na kontrolnu grupu bez probiotika navodeći na zaključak da se deo simvastatina tokom vremena metabolisao pod dejstvom enzima ispitivanih bakterija. Detektovano je i identifikovano 8 metaboličkih produkata simvastatina. Na osnovu izračunatih vrednosti molekulskih deskriptora, očekuje se da će metabolit M-452, koji predstavlja hidroksilovani produkt simvastatinske kiseline, pokazati najbolje rezultate u pogledu fizičko-hemijskih osobina i bioraspoloživosti u biološkom sistemu. Žučne kiseline nisu dovele do statistički značajne modifikacije transporta simvastatina u/iz probiotskih bakterija. Ipak, u nekim vremenskim tačkama primećena je nešto veća koncentracija leka u ekstracelulamom prostoru u grupama sa žučnim kiselinama. Ove razlike se mogu delimično objasniti rezultatima određivanja distribucionog koeficijenta koji su pokazali da ispitivane žučne kiseline dovode do statistički značajnog smanjenja distribucionog koeficijenta simvastatina usled povećanja rastvorljivosti u vodenoj fazi. Rezultatima doking studija procenjeno je da ispitivane žučne kiseline imaju veći afinitet prema čak 80% multidrug transportera ispitivanih bakterija u odnosu na simvastatin što govori o mogućnosti ostvarivanja interakcija žučnih kiselina sa ovim lekom na nivou transportnih proteina probiotskih bakterija. Na osnovu dobijenih rezultata možemo zaključiti da probiotske bakterije imaju ogroman uticaj na sudbinu simvastatina u biološkom sistemu. Uzimajući u obzir činjenicu da probiotske bakterije ulaze u sastav normalne crevne flore i da svaki organizam poseduje specifičan bakterijski sastav, trebalo bi posvetiti više pažnje ispitivanju njegovog uticaja na farmakokinetiku lekova. Neophodna su dalja in vivo ispitivanja kako bi se utvrdila potencijalna farmakološka aktivnost identifikovanih metabolita simvastatina nastalih pod dejstvom enzimske aktivnosti probiotskih bakterija. Povećanje rastvorljivosti simvastatina pomoću žučnih kiselina otvara mogućnost za dalja istraživanja u cilju razvoja novih farmaceutskih formulacija sa poboljšanom bioraspoloživosti i farmakokinetskim osobinama." ]
[ "Interindividual differences in the composition and activity of the gut microflora may affect the metabolism of drugs as well as their final therapeutic response. Simvastatin is drug from the group of statins and has extremely low water solubility, low bioavailability (<5%) and high interindividual differences in therapeutic response whose causes are not fully understood. In recent years, great attention has been paid to studies of bile acids in the development of new pharmaceutical formulations because of their role in the drug solubilization and modification of drug transport through biological membranes. Accordingly, interactions between simvastatin, probiotic bacteria and bile acids were the focus of our research due to great importance and potential influence on the pharmacokinetic and pharmacodynamic properties of simvastatin, and therefore the final therapeutic response in the patients. The aim of the study was to investigate the simvastatin transport and metabolism in probiotic bacteria as well as the effect of various bile acids on drug transport into the bacterial cell. Additonally, the aim was to investigate the influence of bile salts on the distribution coefficient of simvastatin, and the interactions of bile acids with simvastatin at the level of probiotic transport proteins in order to elucidate the nature of expected interactions. Identification and quantification of samples were performed with liquid chromatography-tandem mass spectrometry (LC-MS/MS). Molecular descriptors that describe the physico-chemical and pharmacokinetic properties of identified metabolites were calculated using the software packages VolSurf+ and Molinspiration. Determination of the distribution coefficient was performed using Shake-flask method. Interaction of bile acids with simvastatin at the level of bacterial transport proteins were studied using docking studies with SwissDock program. During the twenty-four hours of incubation with probiotic bacteria, simvastatin concentrations in the extracellular contet showed a statistically significant decrease. The total amount of simvastatin, as the sum of the extracellular and intracellular amount, during the whole study period, was significantly lower in comparison with control group without probiotics, suggesting that the part of simvastatin was metabolized by the enzymatic activity of studied bacteria. Accordingly, eight metabolic products of simvastatin were detected and identified. Based on the calculated values of molecular descriptors, it is expected that the metabolite M-452, which is the hydroxylated product of simvastatin acid, will show the best results in terms of physico-chemical properties and bioavailability in biological system. Bile acids did not show a significant influence on simvastatin transport into probiotic bacteria. However, in some time points, slightly higher drug concentrations in the extracellular medium in groups with bile acids were observed. These differences can be partly explained by the results of the determination of the distribution coefficients which showed that investigated bile acids lead to a statistically significant decrease in simvastatin distribution coefficient due to increased solubility in the aqueous phase. The results of docking studies estimated that studied bile acids have stronger affinities for the 80% of bacterial multidrug transporters compared to simvastatin indicating the possibility of achieving the interactions of bile acids with simvastatin at the level of transport proteins of probiotic bacteria. Based on the obtained results it could be concluded that probiotic bacteria have great influence on the fate of simvastatin in a biological system. Taking into account the fact that probiotic bacteria are the normal part of gut microflora and that each individual has specific bacterial fingerprint, more attention should be paid on studying its influence on drug pharmakocinetics. Further in vivo studies are required in order to determine potential pharmacological activity of identified simvastatin metabolites. Increased water solubility of simvastatin with bile acids may open the possibility for further investigations with the aim of development of new pharmaceutical formulation with improved bioavailability and pharmacokinetic properties." ]
sr (latin script)
Универзитет у Новом Саду, Медицински факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Новом Саду
[ "žučne kiseline i soli", "simvastatin", "probiotici", "farmakokinetika", "membranski transportni proteini", "tečna hromatografija", "crevna mikroflora" ]
[ "Bile Acids and Salts", "Liquid", "Gastrointestinal Microbiome", "Simvastatin", "Probiotics", "Pharmacokinetics", "Membrane Transport Proteins", "Chromatography" ]
[ "Uticaj soli žučnih kiselina na prodor i metabolizam simvastatina u probiotskim bakterijama", "The influence of bile salts on simvastatin transport and metabolism in probiotic bacteria" ]
[ "" ]
doctoralThesis
[ "BY-NC-ND" ]
Миков, Момир; Сувајджић, Љиљана; Стилиновић, Небојша; Вукмировић, Саша; Добрић, Силва; Васовић, Велибор; Станков, Кармен; Ђанић, Маја; Утицај соли жучних киселина на продор и метаболизам симвастатина у пробиотским бактеријама; Утицај соли жучних киселина на продор и метаболизам симвастатина у пробиотским бактеријама;
[ "http://nardus.mpn.gov.rs/bitstream/id/35126/Disertacija4742.pdf", "http://nardus.mpn.gov.rs/bitstream/id/35127/IzvestajKomisije4742.pdf", "https://nardus.mpn.gov.rs/bitstream/id/35127/IzvestajKomisije4742.pdf", "https://nardus.mpn.gov.rs/bitstream/id/35126/Disertacija4742.pdf", "http://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija146642122029412.pdf?controlNumber=(BISIS)101272&fileName=146642122029412.pdf&id=6076&source=NaRDuS&language=sr" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_6661" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/7445
123456789-7445.pdf
yes
no
https://fedorani.ni.ac.rs/fedora/get/o:1219/bdef:Content/download
no
Razvoj i implementacija okvira za evaluaciju i praćenje otvorenosti e-uprave
[ "Stoimenov, Leonid" ]
[ "Milentijević, Ivan", "Janković, Dragan", "Ivković, Miodrag", "Vučetić, Dejan" ]
Veljković, Nataša Ž.
2017-01-30T12:21:26
[ "2017-01-30T12:21:26", "2020-07-03T16:01:55" ]
2016-04-18
[ "http://eteze.ni.ac.rs/application/showtheses?thesesId=4485", "https://nardus.mpn.gov.rs/handle/123456789/7445", "https://fedorani.ni.ac.rs/fedora/get/o:1219/bdef:Content/download", "http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70052&RID=533864086" ]
[ "" ]
[ "The research subject of this PhD thesis is development and implementation of framework for evaluation and monitoring of e-government openness. The research presented in this doctoral dissertation includes definition of a conceptual model of Open government, definition, design and implementation of a framework for evaluation of Open government, definition, design and implementation of Web application architecture that allows evaluation and monitoring of government openness, and finally theoretical and practical validation of framework. Creating the Open government evaluation framework was not possible without a clearly defined concept of Open government, therefore the starting point for this process was clearly defining characteristics of open government that need to be evaluated. The defined Open Government conceptual model, describes Open Government through data openness, data transparency, government transparency, participation and collaboration. On the basis of these aspects following Open government indicators are defined: basic data set, data openness index, government transparency, data transparency, participation and collaboration. Each indicator participates in the final measure – e-government Openness Index with defined constant. Constants’ values are is drafted based on the assessment of the importance of the participation of each of the six indicators in the final measure of e-government Openness Index. Maturity is a measure that relies on the amount of progress that has been made since the last benchmark as well as the experience gained during the entire open government development process. The amount of progress is measured based on current and previous e-government Openness Index values and the number of years that passed between two adjacent benchmarks. Resulting in two measures, that is, one known as the e-government Openness Index and the other Maturity, the framework indicates the progress of government over time, the efficiency of recognizing and implementing new concepts and the willingness of the government to recognize and embrace innovative ideas. The research presented in this PhD dissertation includes definition, design and implementation of Web application architecture for open data analysis and calculation of the evaluation framework’s indicators. Realized Web application enables practical validation of evaluation framework. Also the research includes theoretical validation of the evaluation framework which justifies the reasons for the introduction of the evaluation framework and confirms its validity." ]
application/pdf
sr
Универзитет у Нишу, Електронски факултет
[ "info:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/47003/RS//", "info:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/43007/RS//" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nd/4.0/" ]
Универзитет у Нишу
[ "" ]
[ "" ]
[ "Razvoj i implementacija okvira za evaluaciju i praćenje otvorenosti e-uprave" ]
[ "" ]
doctoralThesis
[ "BY-ND" ]
Стоименов, Леонид; Милентијевић, Иван; Јанковић, Драган; Ивковић, Миодраг; Вучетић, Дејан; Вељковић, Наташа Ж.; Развој и имплементација оквира за евалуацију и праћење отворености е-управе; Развој и имплементација оквира за евалуацију и праћење отворености е-управе;
[ "https://nardus.mpn.gov.rs/bitstream/id/52096/Disertacija7451.pdf", "https://nardus.mpn.gov.rs/bitstream/id/52097/Veljkovic_Natasa.pdf", "http://nardus.mpn.gov.rs/bitstream/id/52096/Disertacija7451.pdf", "http://nardus.mpn.gov.rs/bitstream/id/52097/Veljkovic_Natasa.pdf", "https://fedorani.ni.ac.rs/fedora/get/o:1219/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_7445" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/8246
123456789-8246.pdf
yes
no
https://fedorani.ni.ac.rs/fedora/get/o:1307/bdef:Content/download
no
Otvorena platforma za realizaciju "eCity" koncepta zasnovana na interoperabilnim servisima i servisno orijentisanoj arhitekturi
[ "Stoimenov, Leonid" ]
[ "Rančić, Dejan", "Tošić, Milorad", "Milošević, Danijela" ]
Sukić, Enes Ć.
2017-06-02T18:35:38
[ "2017-06-02T18:35:38", "2020-07-03T16:02:12" ]
2016-09-19
[ "https://nardus.mpn.gov.rs/handle/123456789/8246", "http://eteze.ni.ac.rs/application/showtheses?thesesId=4988", "https://fedorani.ni.ac.rs/fedora/get/o:1307/bdef:Content/download", "http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70052&RID=533880470" ]
[ "" ]
[ "The research topic of this PhD thesis is the use of a variety of open source and freely available, open Web map technologies, services and tools, in order to create city’s electronic services. In the doctoral dissertation are analyzed the modern Web trends and advanced services for the implementation of the eCity concept, as part of eGovernment, which is based on the use of map technology. The doctoral thesis proposes a model of observance of European directives, declarations and action plans which treat the use of geo-information, services and tools with emphasis on interoperability of the created services and centralized distribution model. Emphasis is placed on the use of freely available and open source services, applications and map resources, where geo-information can be created through the collaboration and crowd sourcing process. To create interoperable systems, it is proposed to follow OGC specifications and standards. Doctoral dissertation presents an analysis of the current state of the use of geo-information, GIS tools and free Web map services, as well as trends that treat the creation of geo-information and sharing, especially in the developing countries. The presented eCity concept is based on the integration of information from heterogeneous sources. By analyzing the current situation, the doctoral dissertation recommends the use of Open Source GIS software, as well as the use of OSM resources with exceptional modifying possibilities, based on which they can create interactive map systems and services for the purpose of city’s electronic services. To build eCity concept, a modification of an open platform World Map is proposed, which provides the necessary interoperability of services, tools and resources. The creation of non-specific Web map services is proposed that in many ways enhance the quality of eGovernment towards the citizens and other users at the city level. Based on the proposed model a range of interoperable services can be developed that can be used for the use and distribution of geo-information towards other services, in order to achieve a high degree of rational utilization of resources within the electronic administration, with an increase in the quality of service. This centralization of geo-information and use of freely available services indeed reduces the cost of implementation and use of such systems, which is crucial for e-governance in developing countries." ]
application/pdf
sr
Универзитет у Нишу, Електронски факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Нишу
[ "Web map servisi", "otvorena platforma", "eCity", "interoperabilnost podataka" ]
[ "Web map services", "open platform", "eCity", "interoperability of data" ]
[ "Otvorena platforma za realizaciju \"eCity\" koncepta zasnovana na interoperabilnim servisima i servisno orijentisanoj arhitekturi" ]
[ "" ]
doctoralThesis
[ "BY-NC-ND" ]
Стоименов, Леонид; Тошић, Милорад; Милошевић, Данијела; Ранчић, Дејан; Сукић, Енес Ћ.;
[ "http://nardus.mpn.gov.rs/bitstream/id/52182/Sukic_Enes.pdf", "http://nardus.mpn.gov.rs/bitstream/id/52181/Disertacija.pdf", "https://nardus.mpn.gov.rs/bitstream/id/52181/Disertacija.pdf", "https://nardus.mpn.gov.rs/bitstream/id/52182/Sukic_Enes.pdf", "https://fedorani.ni.ac.rs/fedora/get/o:1307/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_8246" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/8426
123456789-8426.pdf
yes
no
https://fedorani.ni.ac.rs/fedora/get/o:1383/bdef:Content/download
no
Inovacije kao faktor razvoja industrije
[ "Bošković, Gorica" ]
[ "Marjanović, Vladislav", "Mićić, Vladimir" ]
Cvetanović, Dušan S.
2017-07-24T08:19:58
[ "2017-07-24T08:19:58", "2020-07-03T16:01:00" ]
2017-06-12
[ "http://eteze.ni.ac.rs/application/showtheses?thesesId=5137", "https://nardus.mpn.gov.rs/handle/123456789/8426", "https://fedorani.ni.ac.rs/fedora/get/o:1383/bdef:Content/download", "http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70052&RID=533898390" ]
[ "" ]
[ "Innovation is central to economic development and change in its structure. Innovation can be extremely diverse, and, according to the undivided opinion of economic researchers, it dominantly shapes practically all areas of economic activity, including the industrial sector. Relations between innovation and industrial development are extremely complex and often contradictory. This paper analyzes the development of industry on a global scale in the period 1970-2014, by looking at the trend of share of industry in creating a global newly added value, share of industry employees in the structure of total employment, and the share of industrial exports in the value of total exports of individual countries. The analyzed countries are classified into four groups: industrialized economies, economies in the process of industrialization, other developing economies, and least developed economies. By applying statistical and econometric research methods, it is proven that emerging countries, which are at the stage of accelerated industrialization, increase the share of industry in creating a global newly added value, that changes in the level of industry value added, trends in the number of employees, and the structure of exports over time indicate the direction and speed of industrialization and de-industrialization of the world countries. Furthermore, empirical analysis has shown that the growth of the share of innovation-intensive products in the global industry export implies the conclusion of the positive impact of innovation on the development of this area of production. The economic crisis of 2008 had a negative impact on innovation and growth in industrial production, where countries undergoing the process of premature de-industrialization were particularly affected. It is proven that the dynamic technological advances in industry lead to faster productivity growth in it, compared to other sectors of the economy, which, as a rule, means a reduction in the share of industry in total employment. The results of research and development activities, expressed as a number of patent applications per million inhabitants, have had a positive impact on the trend of industrial production in the European Union countries in the period 2003-2010." ]
application/pdf
sr
Универзитет у Нишу, Економски факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Нишу
[ "inovacije", "industrija", "novododata vrednost", "zaposlenost", "uvoz", "patenti", "industrijalizovane privrede", "privrede u procesu industrijalizacije", "deindustrijalizacija", "zrela deindustrijalizacija", "prerana deindustrijalizacija" ]
[ "innovation", "industry", "newly added value", "employment", "import", "patents", "industrialized economies", "economies in the process of industrialization", "deindustrialization", "mature deindustrialization", "premature deindustrialization" ]
[ "Inovacije kao faktor razvoja industrije" ]
[ "" ]
doctoralThesis
[ "BY-NC-ND" ]
Бошковић, Горица; Мићић, Владимир; Марјановић, Владислав; Цветановић, Душан С.; Иновације као фактор развоја индустрије; Иновације као фактор развоја индустрије;
[ "https://nardus.mpn.gov.rs/bitstream/id/52007/Disertacija.pdf", "http://nardus.mpn.gov.rs/bitstream/id/52008/Cvetanovic_Dusan_S.pdf", "https://nardus.mpn.gov.rs/bitstream/id/52008/Cvetanovic_Dusan_S.pdf", "http://nardus.mpn.gov.rs/bitstream/id/52007/Disertacija.pdf", "https://fedorani.ni.ac.rs/fedora/get/o:1383/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_8426" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/8464
123456789-8464.pdf
yes
no
https://fedorani.ni.ac.rs/fedora/get/o:1385/bdef:Content/download
no
Modeli optimizacije izbora lokacije proizvodnih kapaciteta u funkciji lokalnog ekonomskog razvoja
[ "Pešić, Milivoje" ]
[ "" ]
Ranđelović, Milan D.
2017-07-28T14:36:39
[ "2017-07-28T14:36:39", "2020-07-03T16:01:03" ]
2017-05-11
[ "https://nardus.mpn.gov.rs/handle/123456789/8464", "http://eteze.ni.ac.rs/application/showtheses?thesesId=5151", "https://fedorani.ni.ac.rs/fedora/get/o:1385/bdef:Content/download", "http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70052&RID=533898902" ]
[ "" ]
[ "Each day we make decisions, draw conclusions or resolve problems. The environment in which we make decisions is complex and dynamic and yet it influences the whole process as much as one's knowledge, experience, etc. In these situations, the decision making analysis stands out which provides a logic base for defining possible alternatives and the choice of an optimal option from the possible solutions. The decision making analysis helps the decision maker to choose the optimal option in line with his knowledge, reasoning, beliefs and preferences. When there are several criteria the decision making is ambiguous and one needs to find the optimal or the most efficient solution. The multi-criteria decision making can be multi-purposeful. In case the alternatives are explicitly defined and quantified we are dealing with the multi-attribute decision making. The criteria values for the analyzed alternatives can be qualitative and quantitative; therefore, the qualitative ones have to be quantified. Deciding on the location is one of the key elements of logistics and of the importance of the decision making process used by the companies in order to determine where to locate the facility is a decision of crucial importance to all logistic elements and the entire business development of the company. Further on, the contemporary economic, competitive and technological conditions and the business environment comprise a dynamic category, so the currently optimal location may not be optimal in the future. Companies use qualitative and quantitative criteria while deciding on the location of the factory. When deciding on the location of the factory one conducts a detailed analysis due to the dynamic business environment. Constant changes in the environment influence business adjustments. On the contrary, the logistic facilities and their locations are static and are not subject to alteration in a short period of time and in such a way respond to the business environment changes. While making such a decision one needs to use new methodologies and contemporary tools as a decision making support in order to adequately respond to the business environment changes and secure the high quality decision making by taking into account quantitative and qualitative criteria which are important for making a decision on a choice of a location. From the very beginning, local self-governments, worldwide as well as in Serbia, had different roles in the economic development. Local self-governments usually dealt with administrative procedures with no active part in the economic development. By establishing legal grounds local self-governments started improving the business environment and providing support to the business community, but also actively attracting foreign direct investments which have proven to be the key activity of the local economic development. Identification and understanding of the industrial location decision making process within the companies has been identified as a crutial activity which the local self-governments can use in improving the business environment and recruitment of direct investments. On the basis on the prioritization of the quantitative and qualitative decision making criteria in the process of selection a location, local self-governments can improve their business environment if resources are being used optimally and in such a way they support the local economic development by assisting the business community and attracting direct investments. In this paper we established a model which, using the method for decision making in the case of optimization of the industrial location decision making, enables efficient use of the resources of local economic development. The model will enable the identification of criteria / determinant of locations that should be invested in order to promote local economic development, on the basis of a comparison of local governments and types of potential investors. Use of standard methods of multiattribute analysis gives the possibility of a subjective approach to the researcher who must determine in advance the criteria weights, while the application of the model presented in this paper avoids the subjectivity and objectifies the process of preference, a combination of criteria DEA (Data Envelopment Analysis,) and multiattribute analysis methods (AHP, ELECTRE, PROMETHEE, TOPSIS). Within the dissertation, survey conducted, analysed local governments (alternatives) in terms of fulfilling the criteria (location determinants), within which each local government alone determines the criteria weight based on survey of types of potential investors. A comparative analysis of the results of these studies, where other various methods for decision making can be also used, identified the best method, among selected that are the best known and most used, and the result of the dissertation will determine the importance of the location determinants, which will enable to policymakers in field of local economic development, investment promotion and improving business environment at all levels, through the use of the proposed model of efficient planning, the opportunity to efficiently and cost-effectively use the resources at their disposal." ]
application/pdf
sr
Универзитет у Нишу, Економски факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-sa/4.0/" ]
Универзитет у Нишу
[ "višekriterijumska analiza", "višekriterijumsko odlučivanje", "optimizacija", "determinante lokacije", "donošenje odluke o lokaciji", "lokalni ekonomski razvoj", "investicije" ]
[ "multi-criteria analysis", "multi-criteria decision making", "optimization", "location determinants", "location decisionmaking", "local economic development", "investment" ]
[ "Modeli optimizacije izbora lokacije proizvodnih kapaciteta u funkciji lokalnog ekonomskog razvoja" ]
[ "" ]
doctoralThesis
[ "BY-NC-SA" ]
Пешић, Миливоје; Ранђеловић, Милан Д.; Модели оптимизације избора локације производних капацитета у функцији локалног економског развоја; Модели оптимизације избора локације производних капацитета у функцији локалног економског развоја;
[ "https://nardus.mpn.gov.rs/bitstream/id/52021/Disertacija.pdf", "https://nardus.mpn.gov.rs/bitstream/id/52022/Randjelovic_Milan_D.pdf", "http://nardus.mpn.gov.rs/bitstream/id/52021/Disertacija.pdf", "http://nardus.mpn.gov.rs/bitstream/id/52022/Randjelovic_Milan_D.pdf", "https://fedorani.ni.ac.rs/fedora/get/o:1385/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_8464" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/4671
123456789-4671.pdf
yes
no
https://fedorani.ni.ac.rs/fedora/get/o:1022/bdef:Content/download
no
Farmakohemijski aspekti delovanja odabranih 4-fenil hidroksikumarina-integrisana in vitro i komjuterska studija
[ "Nikolić, Goran M." ]
[ "Pešić, Srđan", "Kocić, Gordana", "Stojanović, Dušica", "Mihajilov-Krstev, Tatjana" ]
Veselinović, Jovana B.
2020-07-03T16:07:21
[ "2020-07-03T16:07:21" ]
2015-01-30
[ "http://eteze.ni.ac.rs/application/showtheses?thesesId=2480", "https://nardus.mpn.gov.rs/handle/123456789/4671", "https://fedorani.ni.ac.rs/fedora/get/o:1022/bdef:Content/download", "http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70052&RID=1025169645" ]
[ "" ]
[ "Introduction. Coumarins are widely present in the plant’s kingdom and represent a class of bioactive molecules with different functional groups attached to the basic coumarin structure which can be defined as a lactone where benzene ring is connected to α-piron. It was confirmed that molecules with hydroxyl groups attached to the basic coumarin structure exhibit antioxidant activity since they have the ability to react with free radicals. Coumarins are also considered as potential antibacterial agents which inhibit the ATPase activity of bacterial DNA gyrase. Results from a large number of studies have shown that the spectrum of biological activity of coumarins includes anticancer, anti-inflammatory, antibacterial, anticoagulant and immunomodulatory activity. One of the major goals of medicinal chemistry is to find new molecules with the antioxidant activities, which are capable of reacting with free radicals and neutralize their harmful effects. On the other hand, the morbidity and mortality caused by infectious diseases are still a major health issue. The phenomenon of bacterial resistance to existing antibiotics is one of the biggest problems of today's medicine so that rational use of antibiotics in clinical practice and the development of new antibacterial agents with a broad spectrum of activity present contemporary scientific challenges. The isolation of natural compounds and their application as a leading structure for the chemical modification and further pharmacochemical activity improvement, pharmacophore identification and the establishment of quantitative structure activity relationship (QSAR) parallel with in vitro and computer studies are the subject of modern research. Neoflavones present a group of natural compounds with the basic structure of 4- phenylcoumarin. 4-phenyl hydroxycoumarins have a phenyl group at position 4 and hydroxyl groups attached to the basic coumarin structure and coumarins selected for the study in this doctoral dissertation are: 7-Hydroxy-4-phenyl coumarin (7C), 5,7-dihydroxy-4-phenyl coumarin (5,7C), 7,8-dihydroxy-4-phenyl coumarin (7,8C). Aims of this research were to determine the antioxidant activity of selected 4-phenyl hydroxycoumarins, to establish a relationship between the structure and antioxidant activity with the application of DFT descriptors and to determine the mechanism of antioxidant action on the basis of physico-chemical parameters obtained with DFT calculations, to investigate the antibacterial activity and to establish a correlation between the potential antibacterial activity and the binding affinity of the studied molecules to the active site of bacterial enzymes with the application of computational molecular docking methods, to establish a QSAR models for the studied coumarins’ selected pharmacochemical activity and to assess the physico-chemical and molecular properties in order to predict the bioavailability of the studied 4-phenyl hydroxycoumarins. Methods. For the determination of antioxidant and antibacterial activity of selected 4-phenyl hydroxycoumarins in vitro methods have been used. DPPH•, ABTS•+, ferric thiocyanate method, FRAP and CUPRAC were applied for the determination of antioxidant activity. In addition to the studied compounds, for comparison, the antioxidant activities of commercial synthetic antioxidants (butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT), trolox, and α-tocopherol) were determined and used further as a control group. The significant differences between the antioxidant activity of studied coumarins and standard antioxidants was determined with the application of Dunett’s test (p<0.05 was considered as significant and p<0.01 as a very significant difference). Microdilution method was applied for the determination of antibacterial activity. Modern computer (in silico) methods (DFT, molecular docking, QSAR) are applied for establishing the correlation between the structure and the activity of the studied compounds and to determine the mechanisms by which this correlation is realized. In order to gain insight into the possible mechanisms of antibacterial and anti-HIV activities studied 4-phenyl hydroxycoumarins were subjected to docking simulations. S. aureus tyrosyl-tRNA synthetase, E. coli topoisomerase II DNA gyrase β and HIV-1 integrase have been chosen as target enzymes for the study of inhibitory activity. Results. 7,8C showed significantly higher antioxidant activity (p <0.01) in comparison to standard antioxidants determined with DPPH• and ABTS•+ method, while 7C and 5,7C didn’t show that activity. All tested molecules showed inhibitory effect on lipid peroxidation. After 60 h reaction time the percentage of the inhibition of lipid peroxidation (with 95% confidence interval) was: 56.61 (52.67 to 60.55)% for 7C, 82.48 (75.24 to 89.72)% for 5,7C and 90.939 (88.542 to 93.324)% for 7,8C. Of all the studied coumarin molecules only 7C did not show reducing power determined by FRAP and CUPRAC methods. The slope values (with a confidence interval of 95% and a correlation coefficient r2), which are directly proportional to reducing power were 0.0068 (0.00578-0.00777), 0.929 for 5,7C and 0.0269 (0.0235-0.0303), 0.985 for 7,8C determined with FRAP method and 0.0314 (0.0275-0.0354), 0.994 for 5,7C and 0.059 (0.0548-0.06316), 0.99924 for 7,8C determined with CUPRAC method. The calculated values for the DFT descriptors (HOMO, LUMO, the energy difference, IP, ΔEiso and dipole moment) for the studied coumarins in vacuum, n-octanol, ethanol and water show that of all studied 4-phenyl hydroxycoumarins 7,8C has the highest antioxidant activity, which is in agreement with obtained experimental data. The analysis of the parameters obtained with computational calculations indicate that the HAT is thermodynamically dominant mechanism in the gas phase, while in other studied systems, the most likely mechanism is SPLET. The obtained results for 7,8C show that the thermodynamically favored position of the hydroxyl group in the reactions involving BDE, PDE and ETE parameters is 8 and in the reactions which include the PA parameter is position 7. For 5,7C in the gas-phase favored position of the hydroxyl group in all mechanisms is position 5. In other studied systems, in the reaction mechanisms involving thermodynamic parameters BDE, PDE and ETE position 5 is favored, while in the mechanism that include parameter PA the position 7 is favored. It was determined that studied coumarins show better inhibitory effect against Gram (+) bacteria (MIC values range was from 0.01 to 2.50 mg/mL) in comparison to the Gram (-) (MIC values range was 0.16-10 0 mg/mL). 5,7 C and 7,8C show the weakest inhibitory effect against P. aeruginosa and P. mirabilis, while 7C even at the highest tested concentration of 10 mg/mL didn’t show inhibitory effect. All studied coumarins had the strongest inhibitory effect on the growth of strains of S. aureus, L. monocytogenes, L. innocua and M. luteus. The lowest activity among studied coumarin had 7C. 5,7C showed better inhibitory effect on the majority of the tested strains in comparison to 7,8C. For the interpretation of these results, data obtained by molecular docking studies of the studied compounds for the active site of characteristic enzymes were used. MolDock score values for the binding of the studied 4-phenyl hydroxycoumarins to the active site of tyrosyl tRNA synthetase demonstrated that 5,7C has the highest binding affinity, while 7,8C showed the highest binding affinity to the active site of topoisomerase II DNA gyrase β. Hbond values for the tyrosyl tRNA synthetase showed that 7,8C has the strongest interaction, whereas for the topoisomerase II DNA gyrase β 5,7C has strongest interaction. According to all Score values 7C shows the weakest interactions with the enzymes. Best QSAR models for the inhibition of HIV-1 integrase by a coumarin molecules have the following statistical parameters - for the 3' Processing activity: R2 = 0.9980 and Q2 = 0.9977 for the training set, and R2 = 0.9788 for the test set and for the Integration activity: R2 = 0.9999, and Q2 = 0.9998 for training set and R2 = 0.9213 for the test set. QSAR models are applied to the studied 4- phenyl hydroxycoumarins for calculation and evaluation of their inhibition activities on HIV- 1 integrase. All the obtained score values for the studied coumarins binding to the active site of HIV-1 integrase have shown that 7,8C has the highest binding affinity. Calculated physico-chemical and molecular characteristics showed that the investigated 4-phenyl hydroxycoumarins obey Lipinski rules. Conclusion. 7,8C showed a much more pronounced antioxidant activity in comparison to 7C and 5,7C which indicates that the ortho position of the hydroxyl groups in 4-phenyl hydroxycoumarins significantly contributes to their antioxidant activities. HOMO and LUMO energies and their energy difference of 4-phenyl hydroxycoumarins examined in this study also indicate that 7,8C has the highest antioxidant activity. Between 5,7C and 7C better antioxidant activity has 5,7C. ΔEiso values indicate that 7,8C has the greatest ability to capture free radicals. Total spin density indicates that for all examined hydroxyl groups least favored position in the basic structure of the 4-phenylcoumarins for free-radical reactions is position 7. DFT descriptors as well as obtained experimental data confirm that 7,8C has the highest antioxidative activity in comparison to other studied coumarins. HAT is thermodynamically dominant mechanism in the gas phase, while in other studied systems, the most likely antioxidative mechanism of action of studied coumarins is SPLET. The antibacterial activity of the compounds can be summarized in the following sequence: 7C<7,8C<5.7C. The molecular docking was applied for the evaluation of antibacterial activity on the basis of binding affinity of the studied coumarins in the active sites of tyrosyl tRNA synthetase (S. aureus) and topoisomerase II DNA gyrase β (E.coli). Based on the score values obtained with molecular docking, the binding affinity of the investigated molecules was determined and these results are in agreement with the results of their antibacterial activity. QSAR method was successfully applied for building of a mathematical model for calculating the anti-HIV activity of coumarin molecules on the basis of inhibition of HIV-1 integrase. All studied 4-phenyl hydroxycoumarins obey the Lipinski rules indicating their satisfactory pharmacokinetic profile." ]
application/pdf
sr
Универзитет у Нишу, Медицински факултет
[ "info:eu-repo/grantAgreement/MESTD/Technological Development (TD or TR)/31060/RS//" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Нишу
[ "Hidroksikumarin", "Farmakohemijski aspekt", "4-fenil hidroksikumarini", "antioksidativna aktivnost", "antibakterijska aktivnost", "DFT", "SAR", "QSAR", "Molekulski doking", "pravila Lipinskog" ]
[ "4-phenyl hydroxycoumarins", "antioxidant activity", "antibacterial activity", "DFT", "SAR", "QSAR", "molecular docking", "Lipinski rules" ]
[ "Farmakohemijski aspekti delovanja odabranih 4-fenil hidroksikumarina-integrisana in vitro i komjuterska studija" ]
[ "" ]
doctoralThesis
[ "BY-NC-ND" ]
Николић, Горан М.; Пешић, Срђан; Коцић, Гордана; Стојановић, Душица; Михајилов-Крстев, Татјана; Веселиновић, Јована Б.; Фармакохемијски аспекти деловања одабраних 4-фенил хидроксикумарина-интегрисана ин витро и комјутерска студија; Фармакохемијски аспекти деловања одабраних 4-фенил хидроксикумарина-интегрисана ин витро и комјутерска студија;
[ "https://nardus.mpn.gov.rs/bitstream/id/53219/Veselinovic_Jovana_B.pdf", "https://nardus.mpn.gov.rs/bitstream/id/53218/Disertacija418.pdf", "http://nardus.mpn.gov.rs/bitstream/id/53218/Disertacija418.pdf", "http://nardus.mpn.gov.rs/bitstream/id/53219/Veselinovic_Jovana_B.pdf", "https://fedorani.ni.ac.rs/fedora/get/o:1022/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_4671" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/7452
123456789-7452.pdf
yes
no
no
Razvoj sveobuhvatne metode evaluacije upotrebljivosti web zasnovanih geografskih informacionih sistema za specijalne namene
[ "Rančić, Dejan" ]
[ "Stoimenov, Leonid", "Stojanović, Dragan", "Spalević, Petar" ]
Đorđević, Nebojša D.
2017-01-30T12:21:36
[ "2017-01-30T12:21:36", "2020-07-03T16:02:03" ]
2016-03-08
[ "https://nardus.mpn.gov.rs/handle/123456789/7452", "http://eteze.ni.ac.rs/application/showtheses?thesesId=4497", "http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70052&RID=533864342" ]
[ "" ]
[ "Today, many various kinds of GIS applications are in everyday use. GIS is defined as a set of tools used to collect, store, retrieve, transform and display spatial data from the real world. Today, Web browser is used as a general multi-purpose client application and it provides “well-known” user environment because people are used to use Internet so they know how to work with a web browser. The users of Web-based geographic information systems (Web GIS) are mostly casual end users who have only a very low computer literacy and limited knowledge of GIS technologies. This is why Web-based GIS applications should be designed very carefully and with a strong focus on their usability. Usability is one relevant factor of the quality of Web applications. Recently, it has been receiving great attention, being recognized as a fundamental property for the success of Web applications. Determining the degree of usability is a process in which systems are evaluated in order to determine success product using methods available to the evaluator. One of the current goals of the Web engineering research is defining methods for ensuring usability. Usability as a quality characteristics is defined by many authors and several ISO standards. Many various methods of usability evaluation have been developed. These studies are certainly important as that would further deepen our understanding on factors that contributes towards the usability of Web GIS applications. One important success factor is, therefore, the need to warranty the levels of quality of the Web GIS as software products. High-quality software products are essential to provide value, and avoid potential negative consequences, for the stakeholders. Assessing the quality in use will allow Web GIS application owners to estimate how usable a Web GIS application might be and the user’s satisfaction. User characteristics are also important determinants of usability. The term 'context' includes the characteristics of the users and the work goals they are seeking to achieve, as well as the technical, physical and organizational environments in which they work. Therefore, this PhD thesis describes a practical method for identifying contextual aspects of usability in software systems, and for helping ensure that usability evaluations reflect the context of use and give data with acceptable validity. Attempts to objectively evaluate usability of information systems are old. In order to evaluate the quality of developed systems, a set of quality characteristics and criteria are required as a basis to describe the system quality. During the decades, different literature described various models and attributes of usability. Many usability models have been proposed to allow software usability evaluation. The main purpose of the software product usability model is to specify and assess the level of usability of a product through internal measures of inherent properties of the software, and through external measures of the behavior of the system of which the software is part. Aim of the PhD thesis is to propose a suitable usability model for evaluating the usability of Web-based GIS applications. Researchers have not developed yet any model that precisely describes usability definition and all its attributes that takes into account the varying aspects of usability. It developes a new more comprehensive definition of quality in use, which has usability in use, flexibility in use, satisfaction in use and safety in use as characteristics that can be quantified from the perspectives of different stakeholders, including users, managers and maintainers. Since all of the usability factors do not have the same importance in the overall usability assessment of the WebGIS applications, the proposed factors have been weighted by adopting AHP (Analytic Hierarchy Process) approach. The main goal of this PhD thesis is to propose a comprehensive methodology for usability evaluation and identify the most serious usability problems of special purpose Web-based geographic information system. Usability evaluation can increase software quality and its capability to satisfy users and their needs. The proposed methodology should lead to decreasing time necessary for evaluation of applications and results processing." ]
application/pdf
sr
Универзитет у Нишу, Електронски факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-sa/4.0/" ]
Универзитет у Нишу
[ "Vrednovanje", "Web zasnovani GIS", "upotrebljivost", "kvalitet u upotrebi", "HCI", "AHP", "model kvaliteta", "karakteristike kvaliteta", "zainteresovani" ]
[ "Evaluation", "Web-based GIS", "usability", "quality of use", "HCI", "AHP", "quality model", "quality characteristics", "stakeholders" ]
[ "Razvoj sveobuhvatne metode evaluacije upotrebljivosti web zasnovanih geografskih informacionih sistema za specijalne namene" ]
[ "" ]
doctoralThesis
[ "BY-NC-SA" ]
Ранчић, Дејан; Спалевић, Петар; Стоименов, Леонид; Стојановић, Драган; Ђорђевић, Небојша Д.;
[ "https://nardus.mpn.gov.rs/bitstream/id/52145/Dordevic_Nebojsa_1_a.pdf", "https://nardus.mpn.gov.rs/bitstream/id/52146/Dordevic_Nebojsa.pdf", "http://nardus.mpn.gov.rs/bitstream/id/52145/Dordevic_Nebojsa_1_a.pdf", "http://nardus.mpn.gov.rs/bitstream/id/52146/Dordevic_Nebojsa.pdf" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_7452" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
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[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/4669
123456789-4669.pdf
yes
no
https://fedorani.ni.ac.rs/fedora/get/o:1020/bdef:Content/download
no
Uticaj vremena preduzimanja operativnog lečenja preloma kuka na ishod i komplikacije
[ "Mitković, Milorad" ]
[ "Ristić, Branko", "Milenković, Saša" ]
Radoičić, Dragan K.
2020-07-03T16:07:23
[ "2020-07-03T16:07:23" ]
2015-01-23
[ "https://nardus.mpn.gov.rs/handle/123456789/4669", "http://eteze.ni.ac.rs/application/showtheses?thesesId=2478", "https://fedorani.ni.ac.rs/fedora/get/o:1020/bdef:Content/download", "http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70052&RID=1025165037" ]
[ "" ]
[ "Hip fractures represent a major challenge for today's healthcare systems, especially in countries with burgeoning elderly population, mostly due to mortality and morbidity, and often lengthy hospitalization followed by a number of complications. Patients after hip fracture have a significantly higher mortality after the fracture than patients of the same age without fractures. Numerous studies have linked an increase in mortality and the incidence of complications with delay of surgical treatment. Operative treatment of hip fractures is the treatment of choice, but there are no clearly defined time frames for undertaking of operative treatment. The aim of the study was to determine the influence of timing of surgery for hip fracture outcomes and complications. Based on the findings of the study, early operative treatment of hip fractures, if adequate preparation and selection of patients is conducted, is a safe and in regard to some clinical parameters superior option, compared to delayed surgical treatment. The findings of this study, although give preference to early surgical treatment, do not simplify the choice between early or delayed operative treatment. The question of whether to operate as soon as medical conditions allow, or to delay in accordance with comorbidities or institutional reasons will persist in everyday orthopaedic work. The choice will, in most cases, continue to be the result of a complex compromise between the patient's health status, institutional conditions and the attitude of the attending orthopedic surgeon." ]
application/pdf
sr
Универзитет у Нишу, Медицински факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-sa/4.0/" ]
Универзитет у Нишу
[ "Kuk", "prelomi", "operativno lečenje" ]
[ "" ]
[ "Uticaj vremena preduzimanja operativnog lečenja preloma kuka na ishod i komplikacije" ]
[ "" ]
doctoralThesis
[ "BY-NC-SA" ]
Митковић, Милорад; Ристић, Бранко; Миленковић, Саша; Радоичић, Драган К.; Утицај времена предузимања оперативног лечења прелома кука на исход и компликације; Утицај времена предузимања оперативног лечења прелома кука на исход и компликације;
[ "https://nardus.mpn.gov.rs/bitstream/id/53232/Disertacija416.pdf", "https://nardus.mpn.gov.rs/bitstream/id/53233/Radoicic_Dragan_K.pdf", "http://nardus.mpn.gov.rs/bitstream/id/53232/Disertacija416.pdf", "http://nardus.mpn.gov.rs/bitstream/id/53233/Radoicic_Dragan_K.pdf", "https://fedorani.ni.ac.rs/fedora/get/o:1020/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_4669" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/7153
123456789-7153.pdf
yes
no
https://fedorani.ni.ac.rs/fedora/get/o:1171/bdef:Content/download
no
Značaj histeroskopije u vantelesnom oplođenju
[ "Živadinović, Radomir" ]
[ "Popović, Jasmina", "Petrić, Aleksandra", "Kopitović, Vesna", "Bjelica, Artur" ]
Mitić, Dejan S.
2016-12-24T16:07:54
[ "2016-12-24T16:07:54", "2020-07-03T16:08:27" ]
2016-09-28
[ "https://nardus.mpn.gov.rs/handle/123456789/7153", "http://eteze.ni.ac.rs/application/showtheses?thesesId=4283", "https://fedorani.ni.ac.rs/fedora/get/o:1171/bdef:Content/download", "http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70052&RID=1025594349" ]
[ "" ]
[ "Introduction: Pathological states of the uterus cavity, such as endometrial polyp, submucous myoma, intrauterine synechiae or septum, are considered to be negative influence on IVF success. Hysteroscopy is able to diagnose the possible IVF causes of failure and surgically remove them in the same act. Due to frequent cavum pathology, the idea of applying hysteroscopy, even prior to the first IVF, has been seriously considered. Different studies have also stated that the endometrium proinflammatory response after a local endometrial injury can increase the possibility of successful implantation after an embryo transfer in the IVF cycle. Objective: The aim of the project is to determine the frequency of the cavum pathology with patients in IVF process and to examine the impact of hysteroscopy on IVF outcome in cases of post surgical treatment of pathological states of the uterus, with no pathological substratum and after a local endometrial injury. Method: A study group consisted of 114 patients with hysteroscopy performed 30 to 50 days before the IVF cycle. The control group consisted of 151 patients. The local endometrial injury was done in a way not described in any literature available. Results: Having analyzed the obtained results, almost identical pathology frequency was confirmed prior to the first IVF cycle, as with the next, in nearly a third of the cases. Statistically viewed, significantly higher rates of implantation and pregnancies were obtained after hysteroscopy, in comparison to the control group. Probability of a positive IVF outcome rises 2,1 time after a local endometrial injury, when compared to the control group. Conclusion: Hysteroscopy is minimally invasive, safe and simple method providing higher possibility of conceiving after IVF. This research suggests the protocol for IVF preparing couples to be accompanied by obligatory hysteroscopy even prior to the first IVF cycle." ]
application/pdf
sr
Универзитет у Нишу, Медицински факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Нишу
[ "infertilitet", "histeroskopija", "lokalna endometrijalna povreda", "ishod vantelesnog oplođenja" ]
[ "infertility", "hysteroscopy", "local endometrial injury", "in vitro fertilization outcome" ]
[ "Značaj histeroskopije u vantelesnom oplođenju" ]
[ "" ]
doctoralThesis
[ "BY-NC-ND" ]
Живадиновић, Радомир; Петрић, Aлександра; Копитовић, Весна; Бјелица, Aртур; Поповић, Јасмина; Митић, Дејан С.; Значај хистероскопије у вантелесном оплођењу; Значај хистероскопије у вантелесном оплођењу;
[ "https://nardus.mpn.gov.rs/bitstream/id/53598/Mitic_Dejan.pdf", "https://nardus.mpn.gov.rs/bitstream/id/53597/Disertacija6684.pdf", "http://nardus.mpn.gov.rs/bitstream/id/53597/Disertacija6684.pdf", "http://nardus.mpn.gov.rs/bitstream/id/53598/Mitic_Dejan.pdf", "https://fedorani.ni.ac.rs/fedora/get/o:1171/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_7153" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/11975
123456789-11975.pdf
yes
no
https://fedorani.ni.ac.rs/fedora/get/o:1605/bdef:Content/download
no
Inhibicija dezoksiribonukleaze I derivatima tiazolidina, benzimidazola, 4H- hromena i 5,6,7,8-tetrahidrobenzo[4,5] tieno[2,3-d]pirimidina u in vitro uslovima
[ "Šmelcerović, Andrija" ]
[ "Kocić, Gordana", "Agbaba, Danica", "Milić, Nataša", "Tasić-Kostov, Marija" ]
Kolarević, Ana N.
2020-02-24T11:51:30
[ "2020-02-24T11:51:30", "2020-07-03T16:09:09" ]
2019-07-01
[ "https://nardus.mpn.gov.rs/handle/123456789/11975", "http://eteze.ni.ac.rs/application/showtheses?thesesId=7163", "https://fedorani.ni.ac.rs/fedora/get/o:1605/bdef:Content/download", "http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70052&RID=1026399725" ]
[ "" ]
[ "In this doctoral dissertation the inhibition of deoxyribonuclease I by the derivatives of thiazolidine, benzimidazole, 4H-chromene and 5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine was evaluated in vitro. As a result, 23 compounds, out of 91 tested, inhibited DNase I with IC50 values below 200 μM, including ten thiazolidine, four benzimidazole, one 4H-chromene, and eight 5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine derivatives. These compounds were more effective DNase I inhibitors than crystal violet (IC50 > 300 μM), used as a positive control. According to the Lineweaver-Burk plots, some of the most effective DNase I inhibitors show non-competitive type of inhibition. The intermolecular interactions of the tested compounds with DNase I were predicted by molecular docking studies. To provide a more complete picture of possible therapeutic applications of the investigated thiazolidines, benzimidazoles, 4H-chromenes and 5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidines that inhibited DNase I with IC50 values below 200 μM, in silico study of their physico-chemical, biopharmaceutical, pharmacokinetic, and toxicological properties was performed. Most DNase I inhibitors fulfilled Lipinski’s and Veber’s rules predicting good oral bioavailability in in vitro/in vivo conditions. All compounds were predicted as able to be absorbed by intestine, as well as permeable across blood-brain barrier. Most of the tested derivatives could be preliminary classified as biopharmaceutical class I and/or II. The investigated DNase I inhibitors are generally predicted as slightly toxic and non-carcinogenic compounds, without risk of mutagenic, tumorigenic and/or irritant effects. The general conclusion of this doctoral dissertation is that the most effective DNase I inhibitors from the groups of the investigated thiazolidines, benzimidazoles, 4H-chromenes and 5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidines represent a good basis for the development of novel and more efficient DNase I inhibitors with potential therapeutic applications, considering the importance of DNase I in the pathophysiology of numerous disease conditions. Since there is no DNase I inhibitor defined as a \"gold standard\", the tested compounds could represent a new ones in future research." ]
application/pdf
sr
Универзитет у Нишу, Медицински факултет
[ "info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172044/RS//" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Нишу
[ "Dezoksiribonukleaza I", "Inhibicija", "Tiazolidini", "Benzimidazoli", "4H-Hromeni", "5", "6", "7", "8-Tetrahidrobenzo[4", "5]tieno[2", "3-d]pirimidini", "In silico studija" ]
[ "Deoxyribonuclease I", "Inhibition", "Thiazolidines", "Benzimidazoles", "4H-Chromenes", "5", "6", "7", "8-Tetrahydrobenzo[4", "5]thieno[2", "3-d]pyrimidines", "In silico study" ]
[ "Inhibicija dezoksiribonukleaze I derivatima tiazolidina, benzimidazola, 4H- hromena i 5,6,7,8-tetrahidrobenzo[4,5] tieno[2,3-d]pirimidina u in vitro uslovima" ]
[ "" ]
doctoralThesis
[ "BY-NC-ND" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/53811/Kolarevic_Ana_N.pdf", "http://nardus.mpn.gov.rs/bitstream/id/53810/Disertacija.pdf", "https://nardus.mpn.gov.rs/bitstream/id/53811/Kolarevic_Ana_N.pdf", "https://nardus.mpn.gov.rs/bitstream/id/53810/Disertacija.pdf", "https://fedorani.ni.ac.rs/fedora/get/o:1605/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_11975" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/5553
123456789-5553.pdf
yes
no
https://fedorani.ni.ac.rs/fedora/get/o:1084/bdef:Content/download
no
Solubilni transferenski receptori u dijagnostici anemije zbog deficita gvožđa
[ "Mačukanović-Golubović, Lana" ]
[ "Popović, Stevan", "Kocić, Gordana", "Todorović, Lazar", "Živković, Nenad" ]
Tijanić, Ivan R.
2016-06-25T19:07:47
[ "2016-06-25T19:07:47", "2020-07-03T16:09:00" ]
2015-10-29
[ "https://nardus.mpn.gov.rs/handle/123456789/5553", "http://eteze.ni.ac.rs/application/showtheses?thesesId=3006", "https://fedorani.ni.ac.rs/fedora/get/o:1084/bdef:Content/download", "http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70052&RID=1025409517" ]
[ "" ]
[ "Introduction In recent years, determination of soluble transferrin receptor levels has been emerging as a test that can reliably indicate iron deficiency in various states, and that is non-invasive and easy to use. Objective To determine reference values of sTfR concentrations in serums in our population, to examine the reliability of the method in the diagnosis of anemia due to iron deficiency and associated iron deficiency in anemia accompanying chronic illnesses, to identify possible limitations of the test in certain conditions, to examine the value of combinations with other tests in the diagnosis of mentioned anemia types. Methods The prospective research included 86 patients with anemia: 46 patients with iron-deficiency anemia, and 40 patients with anemia of a chronic disease. The control group consisted of 40 healthy persons aging over 18. It was performed at the Clinic of Hematology, while laboratory tests were conducted in the Immunology and Biochemistry Laboratory of the Clinical Center Niš. Values of complete blood count, iron and iron-binding capacity in serum, ferritin and soluble transferrin receptors were determined. Results Ferritin values were reduced in 76.1% of patients, while higher levels of soluble transferrin receptors appeared in 100% of patients with anemia due to iron deficiency. In patients with reduced serum ferritin levels, sTfR/log ferritin index was statistically significantly higher than in patients in whom ferritin concentration was in the normal range (p <0.001). ROC analysis of patients with anemia due to iron deficiency showed that sTfR/log ferritin index (AUC 0.992) and levels of soluble transferrin receptors (AUC 0.986) occupied the largest area under the curve, thus representing the best diagnostic markers for these patients. The best diagnostic parameter for detecting iron deficiency in patients with anemia of a chronic disease by ROC analysis is the sTfR/log ferritin index (AUC 0.770). Conclusion Soluble transferrin receptors are useful in the diagnosis of anemia due to iron deficiency, especially when ferritin values are not reduced. The calculation of sTfR/log ferritin index is even more reliable. In patients with anemia of a chronic disease, the associated iron deficiency could be best indicated by sTfR/log ferritin index" ]
application/pdf
sr
Универзитет у Нишу, Медицински факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by/4.0/" ]
Универзитет у Нишу
[ "solubilni transferinski receptori", "feritin", "deficit gvožđa", "anemija" ]
[ "soluble transferrin receptors", "ferritin", "iron deficiency", "anemia" ]
[ "Solubilni transferenski receptori u dijagnostici anemije zbog deficita gvožđa" ]
[ "" ]
doctoralThesis
[ "BY" ]
Мачукановић-Голубовић, Лана; Поповић, Стеван; Коцић, Гордана; Тодоровић, Лазар; Живковић, Ненад; Тијанић, Иван Р.; Солубилни трансференски рецептори у дијагностици анемије због дефицита гвожђа; Солубилни трансференски рецептори у дијагностици анемије због дефицита гвожђа;
[ "https://nardus.mpn.gov.rs/bitstream/id/53755/Tijanic_Ivan_R.pdf", "http://nardus.mpn.gov.rs/bitstream/id/53755/Tijanic_Ivan_R.pdf", "https://nardus.mpn.gov.rs/bitstream/id/53754/Disertacija3535.pdf", "http://nardus.mpn.gov.rs/bitstream/id/53754/Disertacija3535.pdf", "https://fedorani.ni.ac.rs/fedora/get/o:1084/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_5553" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/7414
123456789-7414.pdf
yes
no
https://fedorani.ni.ac.rs/fedora/get/o:1199/bdef:Content/download
no
Komparativna analiza rezultata lečenja karcinoma rektuma metodama totalne mezorektalne ekscizije i transsekcije mezorektuma
[ "Stanojević, Goran" ]
[ "Stojanović, Miroslav", "Krivokapić, Zoran" ]
Milojković Vlačić, Bobana D.
2017-01-13T10:12:12
[ "2017-01-13T10:12:12", "2020-07-03T16:08:02" ]
2016-09-02
[ "https://nardus.mpn.gov.rs/handle/123456789/7414", "http://eteze.ni.ac.rs/application/showtheses?thesesId=4429", "https://fedorani.ni.ac.rs/fedora/get/o:1199/bdef:Content/download", "http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70052&RID=1025595117" ]
[ "" ]
[ "Colorectal cancer (CRC) remains a significant medical problem world wide, despite ‘advances in medicine and locoregional control of the disease. The success of surgical treatment of rectal cancer is measured by the rate of complication and survival of patients. The decision on the most suitable type of surgical procedure and mesorectal excision - total mesorectal excision (TME) or partial mesorectal excision (PME) - is influenced by a number of factors, among which the localisation and disease stage are most importent. There is a question whether PME is appropriate for patients suffering from cancer located in the middle third of the rectum, where the additional 3 cm distance between the anocutaneous line and the tumour is sufficient for preventing malignant deposits within the distal mesorectum. The aims of this study were to determine and compare the number of patients in each experimental group (TME/PME) affected by anastomotic leakage and stenosis, local recurrence and nerve damage. To establish the risk factor for leakage and local recurrence using the analysis of variance; to determine the number of nonspecific compilation in the experimental groups; to determine the survival rate of patients in the experimental groups. The research was conducted at the General Surgery Clinic of the Clinical Centre of Nis. The clinical prospective study encompassed 84 patients suffering from colorectal cancer who were operated on using the TME (55 patients) and PME (33 patients) methods in the period from June 2013 to December 2014. Obtained results pointed to a statistically significant difference was found in the chosen type of mesorectal excision with respect to the localisation of the rectal cancer. It was established that leakage was more common in patients that underwent TME. The results of the doctoral thesis show that there was no significant difference in the incidence of recurrence between the experimental groups. It was also observed that there was no significant difference between the groups with respect to stenosis. The analysis of results showed a statistically significantly greater incidence of nerve damage in patients in the TME group. A greater percentage of patients in the PME group exhibited nonspecific compilations, but the difference between the two groups was not statistically significant. There was no significant difference in morality with respect to mesorectal excision. The results showed that localisation was a statistically significant independent risk factor for the appearance leakage and type of mesorectal excision. The stage of the tumour was a statistically significant risk factor for recurrence. The analysis of outcomes in patients with cancer in the middle third of the rectum showed that leakage was more common in the TME group, compared to the PME group. However, local occupance was not found to be affected by the type of mesorectal excision, but instead was solely influenced by the stage of the tumour. Incidence of nonspecific compilations was shown to be equal between the two experimental groups. The analysis of results revealed no significant difference in the rate of survival between the two groups during the monitoring period. Based on the information outlined above, it can be concluded that partial mesorectal excision can be used in select cases of cancers localised to the middle third of the rectum with the full application of oncological principles of radicalism." ]
application/pdf
sr
Универзитет у Нишу, Медицински факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Нишу
[ "Karcinom rektuma", "totalna mezorektalna ekscizija", "transsekcija mezorektuma" ]
[ "Rectal cancer", "total mesorectal excision", "transection of mesorectum" ]
[ "Komparativna analiza rezultata lečenja karcinoma rektuma metodama totalne mezorektalne ekscizije i transsekcije mezorektuma" ]
[ "" ]
doctoralThesis
[ "BY-NC-ND" ]
Станојевић, Горан; Кривокапић, Зоран; Стојановић, Мирослав; Милојковић Влачић, Бобана Д.; Компаративна анализа резултата лечења карцинома ректума методама тоталне мезоректалне ексцизије и транссекције мезоректума; Компаративна анализа резултата лечења карцинома ректума методама тоталне мезоректалне ексцизије и транссекције мезоректума;
[ "http://nardus.mpn.gov.rs/bitstream/id/53431/Milojkovic_Vlacic_Bobana_D.pdf", "https://nardus.mpn.gov.rs/bitstream/id/53431/Milojkovic_Vlacic_Bobana_D.pdf", "https://nardus.mpn.gov.rs/bitstream/id/53430/Disertacija7299.pdf", "http://nardus.mpn.gov.rs/bitstream/id/53430/Disertacija7299.pdf", "https://fedorani.ni.ac.rs/fedora/get/o:1199/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_7414" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/7462
123456789-7462.pdf
yes
no
https://fedorabg.bg.ac.rs/fedora/get/o:1214/bdef:Content/download
yes
Sekundarni metaboliti predstavnika roda Sedum L. (Crassulaceae) centralnog Balkanskog poluostrva i njihov hemotaksonomski značaj
[ "Stojanović, Gordana" ]
[ "Zlatković, Bojan", "Jovanović, Olga", "Petrović, Goran", "Božin, Biljana" ]
Jovanović, Snežana Č.
2017-01-30T12:23:33
[ "2017-01-30T12:23:33", "2020-07-03T16:12:08" ]
2016-10-07
[ "https://nardus.mpn.gov.rs/handle/123456789/7462", "http://eteze.ni.ac.rs/application/showtheses?thesesId=4473", "https://fedorabg.bg.ac.rs/fedora/get/o:1214/bdef:Content/download", "http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70052&RID=1025365225" ]
[ "" ]
[ "The aim of this doctoral dissertation was the estimation of chemotaxonomic utility of secondary metabolites of the selected members from the genus Sedum L. (Crassulaceae), collected from the Central Balkan Peninsula. The study also included compatriots from the related genera (same family): Crassula L., Hylotelephum H. Ohba, Echeveria DC. and Kalanchoe Adans. Distribution of n-alkanes (C20-C35) and tirterpenes (olenanae, lupane and taraxerane) were monitored in hexane extracts by GC-MS and GC-FID techniques, while polar components, from methanol extracts, were monitored by HPLC technique. The contents of mentioned components were inputted uniformly in matrices (pattern) further used in statistical analyses: descriptive, univariate and multivariate methods. Distribution of characters was considered on the series level as a taxonomic rank. Different contents contributed to certain classification of examined taxa which was discussed with respect to already established systems of classification related to genus." ]
application/pdf
sr
Универзитет у Нишу, Природно-математички факултет
[ "info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172047/RS//" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Нишу
[ "" ]
[ "Sedum L.", "secondary plant metabolites", "epicuticular waxes", "methanol extracts", "chemotaxonomy" ]
[ "Sekundarni metaboliti predstavnika roda Sedum L. (Crassulaceae) centralnog Balkanskog poluostrva i njihov hemotaksonomski značaj" ]
[ "" ]
doctoralThesis
[ "BY-NC-ND" ]
Стојановић, Гордана; Златковић, Бојан; Јовановић, Олга; Петровић, Горан; Божин, Биљана; Јовановић, Снежана Ч.; Секундарни метаболити представника рода Седум Л. (Црассулацеае) централног Балканског полуострва и њихов хемотаксономски значај; Секундарни метаболити представника рода Седум Л. (Црассулацеае) централног Балканског полуострва и њихов хемотаксономски значај;
[ "http://nardus.mpn.gov.rs/bitstream/id/54272/Jovanovic_Snezana_C.pdf", "https://nardus.mpn.gov.rs/bitstream/id/54272/Jovanovic_Snezana_C.pdf", "https://nardus.mpn.gov.rs/bitstream/id/54271/Dis_UNI_Snezana_Jovanovic_2016.pdf", "http://nardus.mpn.gov.rs/bitstream/id/54271/Dis_UNI_Snezana_Jovanovic_2016.pdf", "https://fedorabg.bg.ac.rs/fedora/get/o:1214/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_7462" ]
[ "" ]
[ "" ]
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https://nardus.mpn.gov.rs/handle/123456789/3317
123456789-3317.pdf
yes
no
https://nardus.mpn.gov.rs/bitstream/handle/123456789/3317/disertacija.pdf?sequence=2&isAllowed=y
yes
Religija i hodočasnički turizam : studija slučaja tri svetilišta u Srbiji (Kalemegdanska Sv. Petka, Bogorodica Đuniska i Majka Božja Tekijska)
Religion and pilgrim tourism: case studies three anctuaries in Serbia (St. Petka chapel of Kalemegdan, Holy Mother of Đunis and Holy Mother of Tekije)
[ "Vukomanović, Milan" ]
[ "Bogdanović, Marija", "Đorđević, Dragoljub" ]
Radisavljević-Ćiparizović, Dragana
2016-01-05T12:54:30
[ "2016-01-05T12:54:30", "2020-07-03T10:03:33" ]
2013-12-25
[ "https://nardus.mpn.gov.rs/handle/123456789/3317", "http://eteze.bg.ac.rs/application/showtheses?thesesId=1608", "https://fedorabg.bg.ac.rs/fedora/get/o:9065/bdef:Content/download", "http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=523678615" ]
[ "U našoj tezi se bavimo definisanjem i razgraničavanjem pojmova hodočašća, kao pokloničkog putovanja poznatog od davnina, i verskog turizma, kao savremenog vida putovanja i odmora. Pod hodočašćem podrazumevamo odlazak na neko sveto mesto koje se prihvata od strane vernika kao sveto i za koje se veruje da se u njemu dešavaju isceljenja. Ono se odvija s namerom duhovnog prosvetljenja i preobraţenja, i utoliko se moţe svrstati u obrede prelaza: početak putovanja odgovara odvajanju od ranijeg načina ţivota, samo putovanje označava prelazni stupanj od svetovnog na sveto, a povratak s puta simbolizuje preporod povezan sa osećanjem proţetosti svetim. Mešovita hodočašća podrazumevaju da u jedno svetilište odlaze vernici različitih vera i konfesija, privučeni svetim mestom i svetim trenutkom. Sveta mesta, mesta hodočašća, su bila posećena i u vreme najveće, politički isforsirane, sekularizacije našeg društva, pa moţemo reći da su bila jača od ideologije ateizma. Povratak narodnoj religioznosti je, u našem slučaju, prethodio desekularizaciji. U radu su predstavljene studije slučaja tri svetilišta u Srbiji koja posećuju ljudi bez obzira na veru i konfesiju. To su Kapela Sv. Petke na Kalemegdanu u Beogradu, Pokrov Presvete Bogorodice u Đunisu kod Kruševca u Centralnoj Srbiji, i svetilište Majke Boţje Tekijske kod Petrovaradina u Vojvodini. Prva dva svetilišta pripadaju pravoslavnoj, a treće rimokatoličkoj konfesiji. Analizira se odnos svetog i svetovnog na hodočašćima i susret crkvene i narodne religioznosti kroz rituale na centralne praznike. Istraţivanje je sprovedeno metodom dubinskog polustrukturisanog intervjua sa hodočasnicima pravoslavne i rimokatoličke veroispovesti. Sa Romima, muslimanima, vođeni su razgovori u Tekijama i Đunisu koji su snimljeni kamerom. Glavni nalazi istraţivanja pokazuju da su motivi hodočašća najvećeg broja ispitanika duhovne prirode, bogotraţiteljski, i da hodočašća pozitivno utiču na njihov svakodnevni ţivot. Ispitivani hodočasnici su najčešće praktični crkveni vernici, dok je manje tradicionalista. Hodočasnici obe hrišćanske konfesije ne pripadaju većini savremenih vernika u Srbiji, već manjini crkvenih vernika. Skoro svi ispitanici smatraju da dolazi do izvesnog komunitasa na hodočašćima, što najviše zavisi od vođe puta, tj. sveštenika koji vodi grupu. Romi, muslimani masovno porodično dolaze u hrišćanska svetilišta na određene praznike, ali svoje obrede vrše odvojeno od hrišćanskih grupa. Dakle, ne ostvaruje se komunitas, ali najčešće nema ni sukoba. Napetu atmosferu moţe izazvati neusklađen tajming posete svetilištu, na primer kada Romi, muslimani dolaze u pravoslavni manastir poštujući rimokatolički kalendar (Đunis). Mešovita hodočašća u Srbiji, pored tradicije, odrţava vera hodočasnika u Boga, svece čudotvorce i isceliteljska mesta. Ovaj rad je skroman doprinos doskora zanemerenoj temi hodočašća, i boljem razumevanju, s jedne strane, rituala i religioznog iskustva hodočasnika, a s druge strane, verskog turizma u Srbiji." ]
[ "In our thesis we deal with the definiing and demarcating of pilgrimage terms, the pilgrimage journey known since ancient times, and religious tourism as a modern form of travel and leisure. Under the the term pilgrimage there is a meaning of going to a sacred place that is accepted by the believers as sacred and believed to be the place of healing. It is being done with the intention of spiritual enlightenment and transformation, and thus can be classified as a rite of passage: commencement of travel is appropriate to the separation from the former way of life, the journey marks the transitional stage from the secular to the sacred, and the return from the journey symbolizes the rebirth associated with the feeling of being imbued with sacred. Mixed pilgrimages mean that believers of different faiths and denominations go to one sanctuary, attracted by sacred place and sacred moment. Holy places, pilgrimage sites, were being visited even at the times of the largest, politically contrived, secularization of our society, so we can say that they were stronger than the ideology of atheism. Return to the folk religiosity happened, in our case, prior to desecularization. This paper presents case studies of three shrines in Serbia, which are visited by people regardless of their religion or confession. These are the Chapel of St. Petka at Kalemegdan in Belgrade, the Church of the Holy Virgin Cover in Djunis near Krusevac in central Serbia, and the Sanctuary of Our Lady of Tekije near Petrovaradin in Vojvodina. The first two sanctuaries belong to the Orthodox, and the third one to the Roman Catholic confession. The relationship between the sacred and the secular pilgrimages and encounter between church and folk religiosity is analysed through the central rituals on the main holidays. The study was conducted using the method of semi-structured in-depth interviews with pilgrims of Orthodox and Roman Catholic confession. Interviews with Romani people, muslims, were held in the Tekije and Djunis, captured by a camera. The main findings show that the pilgrimage motives of the majority of respondents are of spiritual, God-seeking, and that pilgrimages positively affect their daily lives. Interviewed pilgrims were usually practical church believers, while there IV were less of traditionalists. Pilgrims of both Christian denominations do not belong to the majority of contemporary believers in Serbia, but to the minority of church believers. Almost all respondents feel that certain Communitas occur on pilgrimages, which to the great extent depends on the group leader, i.e. priest who leads the group. Romani people, muslims come to Christian shrines on certain holidays with their families in great numbers, but their rituals are performed separately from the Christian groups. So, the Communitas doe not occur, but usually there are no conflicts either. Tense atmosphere can be caused by uncoordinated timings of visits to the shrine, such is when the Romani people, Muslims come to the Orthodox monastery respecting the Roman Catholic calendar (Djunis). Mixed pilgrimages in Serbia, besides tradition, are characterized ny the pilgrims’ faith in God, the saints who are miracle workers and places of healing. This paper is a modest contribution to the, up to the recently neglected theme of pilgrimage, and to a better understanding of, on the one hand, rituals and religious experience of the pilgrims, and on the other hand, religious tourism in Serbia." ]
application/pdf
sr
Универзитет у Београду, Филозофски факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Београду
[ "hodočašće", "hodočasnici", "verski turizam", "narodna religioznost", "crkvena religioznost", "sveta mesta", "sveto vreme", "sekularizacija", "desekularizacija", "Srbija" ]
[ "pilgrimage", "pilgrims", "religious tourism", "folk religiosity", "church religiosity", "holy place", "holy time", "secularization", "desecularization", "Serbia" ]
[ "Religija i hodočasnički turizam : studija slučaja tri svetilišta u Srbiji (Kalemegdanska Sv. Petka, Bogorodica Đuniska i Majka Božja Tekijska)", "Religion and pilgrim tourism: case studies three anctuaries in Serbia (St. Petka chapel of Kalemegdan, Holy Mother of Đunis and Holy Mother of Tekije)" ]
[ "" ]
doctoralThesis
[ "BY-NC-ND" ]
Вукомановић, Милан; Богдановић, Марија; Ђорђевић, Драгољуб; Радисављевић-Ћипаризовић, Драгана; Религија и ходочаснички туризам : студија случаја три светилишта у Србији (Калемегданска Св. Петка, Богородица Ђуниска и Мајка Божја Текијска); Религија и ходочаснички туризам : студија случаја три светилишта у Србији (Калемегданска Св. Петка, Богородица Ђуниска и Мајка Божја Текијска);
[ "http://nardus.mpn.gov.rs/bitstream/id/153908/disertacija.pdf", "https://fedorabg.bg.ac.rs/fedora/get/o:9065/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_3317" ]
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https://nardus.mpn.gov.rs/handle/123456789/21727
123456789-21727.pdf
yes
no
https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija168906945703461.pdf?controlNumber=(BISIS)130767&fileName=168906945703461.pdf&id=21870&source=NaRDuS&language=sr
no
Anatomska karakterizacija vegetativnih organa vrba (Salix spp.) u ciljuselekcije genotipova u fitoremedijaciji
Anatomical characterization of the willow (Salix spp.) vegetative organs forselection of genotypes in the phytoremediation
[ "Luković, Jadranka" ]
[ "Zorić, Lana", "Luković, Jadranka", "Borišev, Milan", "Pilipović, Andrej" ]
Хркић Илић, Зорана
2023-10-04T13:57:44
[ "2023-10-04T13:57:44" ]
2023-09-29
[ "https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija168906945703461.pdf?controlNumber=(BISIS)130767&fileName=168906945703461.pdf&id=21870&source=NaRDuS&language=sr", "https://www.cris.uns.ac.rs/record.jsf?recordId=130767&source=NaRDuS&language=sr", "https://www.cris.uns.ac.rs/DownloadFileServlet/IzvestajKomisije168906946924839.pdf?controlNumber=(BISIS)130767&fileName=168906946924839.pdf&id=21871&source=NaRDuS&language=sr", "https://nardus.mpn.gov.rs/handle/123456789/21727" ]
[ "Vrbe (Salix spp.) imaju značajnu ulogu u fitoremedijaciji potencijalno toksičnih elemenata i organskih polutanata. Podaci o anatomskim i hidrauličkim osobinama vegetativnih organa vrba pod uticajem Cd su malobrojni ili uopšte nisu dostupni. Da bi se identifikovali genotipovi vrba koji imaju visok potencijal primjene u projekttima fito(dendro)remedijacije kadmijuma, tri klona Salix alba L. klon ‘B-44’, Salix viminalis L. klon ‘SV068’ i Salix matsudana Koidz. klon ‘SM4041’ gajena su metodom zemljišnih kultura u prisustvu kadmijuma sa ili bez dodatka limunske kiseline. Anatomskom analizom su utvrđene genotipske specifičnosti u parametrima vegetativnih organa, idrauličnoj teorijskoj provodljivosti ksilema korijena, reznice i izbojka i otpornosti na kavitaciju i embolizam. Definisane su intergenotipske varijabilnosti kvantitativnih karaktera nadzemnih i podzemnih segmenata reznica, adventivnih korijenova, izbojaka i liski odabranih klonova vrba, koje imaju značaj u potpunijem poznavanju anatomske građe vrsta iz roda Salix. Stereološka analiza pružila je nove, do sada nepoznate podatke o volumenskim gustinama izbojaka vrba. Anatomskom analizom vegetativnih organa klonova vrba izvršenom u tri faze tokom rasta biljaka, utvrđeno je postojanje intergenotipskih razlika na anatomskom planu u zavisnosti od reakcija na tretmane Cd i Cd u prisustvu limunske kiseline i dužine trajanja tretmana, tj. Faze uzorkovanja. Zapažene varijacije kvantitativnih parametara vegetativnih organa mogu biti polazna tačka u programima selekcije genotipova vrba koji se gaje i istražuju za različite primjene, uključujući selekciju genotipova sa poboljšanim nivoom rasta daptabilnosti i otpornosti na faktore stresa, uključujući povećane koncentracije potencijalno toksičnih elemenata u zemljištu, vodi i vazduhu. Na osnovu dobijenih podataka karakteristike traheja i hidrauličke osobine ksilema su identifikovani kao anatomskih parametri povezani sa mehanizmima tolerancije, akumulacije i translokacije elemenata u vegetativnim organima vrba i imaju ulogu svojevrsnog vodiča u produkciji i selekciji genotipova najpogodnijih za fitoekstrakciju i fitostabilizaciju. Rezultati ove disertacije pokazuju da se među analiziranim genotipovima vrba, klon 'B-44' ističe kao genotip sa svojstvima poželjnim za fitostabilizaciju, a klonovi 'SV068' i 'SM4041' za fitoekstrakciju kadmijuma. Dodavanje limunske kiseline zemljištu kontaminiranog Cd može se smatrati poželjnom i dgovarajućom mjerom dendroremedijacije, koja doprinosi povećanju usvajanja i akumulacije Cd u vegetativnim organima odabranih klonova vrbe, a samim tim i efikasnijem uklanjanju Cd iz zagađenog zemljišta." ]
[ "Willows (Salix spp.) have a significant role in the phytoremediation of potentially toxic elements and organic pollutants. Data on the anatomical and hydraulic properties of the vegetative organs of willows under the influence of Cd are few or not available at all. To identify willow genotypes that have a high potential for application in cadmium phyto(dendro)remediation projects, three clones, Salix alba L. clone 'B-44', Salix viminalis L. clone 'SV068' and Salix matsudana Koidz. clone 'SM4041' were cultivated by the method of soil culture in the presence of cadmium with or without the addition of citric acid. Anatomical analysis determined genotypic specificities in the parameters of vegetative organs, hydraulic theoretical conductivity of the xylem of root, cutting and shoot and resistance to cavitation and embolism. Intergenotypic variability of quantitative characters of aboveground and underground segments of cuttings, adventitious roots, shoots and leaves of selected willow clones are defined, which have significance in a more complete knowledge of the anatomical structure of species from the genus Salix. Stereological analysis provided new, so far unknown data on the volume densities of willow shoots. By the anatomical analysis of the vegetative organs of willow clones carried out in three phases during plant growth, intergenotypic differences on the anatomical plane are found, depending on reactions to treatments with Cd and Cd in the presence of citric acid and the duration of treatments, i.e. sampling phases. Determined variations of the quantitative parameters of vegetative organs may be the starting point in the programs of the selection of willow genotypes that are grown and investigated for a variety of applications, including genotype selection with improved levels of growth, adaptability, and resistance to stress factors, including increased concentrations of potentially toxic elements in soil, water and air. Based on the obtained data, vessels characteristics and hydraulic properties of the xylem are identified as the anatomical parameters associated with the mechanisms of tolerance, accumulation and translocation of elements in the vegetative organs of willows and have the guiding role in the production and selection of genotypes most suitable for phytoextraction and phytostabilization. The results of this dissertation show that among the analyzed willow genotypes, clone 'B-44' stands out as a genotype with properties desirable for phytostabilization, and clones 'SV068' and 'SM4041' for cadmium phytoextraction. The addition of citric acid to the soil contaminated with Cd can be considered a desirable and appropriate measure of dendroremediation, which contributes to an increased adoption and accumulation of Cd in the vegetative organs of selected willow clones, and therefore more effective removal of Cd from polluted soil." ]
sr (latin script)
Универзитет у Новом Саду, Природно-математички факултет
[ "" ]
[ "openAccess" ]
[ "" ]
Универзитет у Новом Саду
[ "Salix", "klon", "kadmijum", "limunska kiselina", "anatomija", "stereologija", "dendroremedijacija" ]
[ "Salix", "clone", "cadmium", "citric acid", "anatomy", "stereology", "dendroremediation" ]
[ "Anatomska karakterizacija vegetativnih organa vrba (Salix spp.) u ciljuselekcije genotipova u fitoremedijaciji" ]
[ "Anatomical characterization of the willow (Salix spp.) vegetative organs forselection of genotypes in the phytoremediation" ]
doctoralThesis
[ "Attribution-NonCommercial-ShareAlike" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/153711/Disertacija_14078.pdf", "http://nardus.mpn.gov.rs/bitstream/id/153712/Izvestaj_komisije_14078.pdf", "https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija168906945703461.pdf?controlNumber=(BISIS)130767&fileName=168906945703461.pdf&id=21870&source=NaRDuS&language=sr" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_21727" ]
[ "" ]
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https://nardus.mpn.gov.rs/handle/123456789/21744
123456789-21744.pdf
yes
no
http://nardus.mpn.gov.rs/bitstream/id/153762/Disertacija_14037.pdf
no
Ефекти интегрисаног неуромишићног вежбања у настави физичког васпитања
Efekti integrisanog neuromišićnog vežbanja u nastavi fizičkog vaspitanja
[ "Batez (Bigović), Maja" ]
[ "Đorđić (Todorović), Višnja", "Stojanović, Marko", "Radisavljević-Janić, Snežana" ]
Sindic, Marijana
2023-10-04T14:01:10
[ "2023-10-04T14:01:10" ]
2021-09-10
[ "https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija162212424619666.pdf?controlNumber=(BISIS)117848&fileName=162212424619666.pdf&id=17852&source=NaRDuS&language=sr", "https://www.cris.uns.ac.rs/record.jsf?recordId=117848&source=NaRDuS&language=sr", "https://www.cris.uns.ac.rs/DownloadFileServlet/IzvestajKomisije16221242591734.pdf?controlNumber=(BISIS)117848&fileName=16221242591734.pdf&id=17853&source=NaRDuS&language=sr", "https://nardus.mpn.gov.rs/handle/123456789/21744" ]
[ "Циљ истраживања je испитивање ефеката примене осмонедељног интегрисаног неуромишићног вежбања на часу физичког васпитања код деце млађег школског узраста на моторичке вештине, физичку форму повезану са здрављем и функционалну покретљивост. Истраживање је започето у септембру 2019. године, а завршено је у децембру исте године. Узорак испитаника чинило је 137 ученика другог разреда основне школе „Прва војвођанска бригада“ из Новог Сада (72 девојчице и 65 дечака). Одељења су насумично подељена у две групе: два одељења чинила су експерименталну групу (N=60), а три одељења контролну групу (N=77). Експерименална група реализовала је експериментални програм два пута недељно у уводних ~15 минута часа физичког васпитања који се састојао од: динамичког загревања, основних вежби које су фокусиране на повећање мишићне експлозивности, снаге мишића доњих екстремитета и снаге мишића трупа и секундарних вежби које имају за циљ побољшање фундаменталних моторичких вештина. Контролнa група имала је традиционални час физичког васпитања, такође два пута недељно. Након уводних ~15 минута ученици експерименталне групе су реализовали идентичне активности као контролна група у главном и завршном делу часа. У циљу евалуације ефеката експерименталног и контролног програма, примењене су се следеће батерије тестова: за процену моторичких вештина Test of Gross Motor Development, за процену компоненти физичке форме повезане са здрављем Fitnessgram и за процену функционалне покретљивости Functional Movement System. У циљу утврђивања квантитативних ефеката експерименталног и контролног програма примењена је комбинована анализа варијансе за поновљена мерења. За праћење напретка групе као статистичка мера користила се величина ефекта. Резултати истраживања указали су на ефикасност интегрисаних неуромишићних вежби на часовима физичког васпитања. Након примењених програма, на основу добијених резултата уочиле су се веће промене код експерименталне групе у односу на контролну групу у појединим варијаблама моторичких вештина, физичке форме повезане са здрављем и функционалне покретљивости.", "Cilj istraživanja je ispitivanje efekata primene osmonedeljnog integrisanog neuromišićnog vežbanja na času fizičkog vaspitanja kod dece mlađeg školskog uzrasta na motoričke veštine, fizičku formu povezanu sa zdravljem i funkcionalnu pokretljivost. Istraživanje je započeto u septembru 2019. godine, a završeno je u decembru iste godine. Uzorak ispitanika činilo je 137 učenika drugog razreda osnovne škole „Prva vojvođanska brigada“ iz Novog Sada (72 devojčice i 65 dečaka). Odeljenja su nasumično podeljena u dve grupe: dva odeljenja činila su eksperimentalnu grupu (N=60), a tri odeljenja kontrolnu grupu (N=77). Eksperimenalna grupa realizovala je eksperimentalni program dva puta nedeljno u uvodnih ~15 minuta časa fizičkog vaspitanja koji se sastojao od: dinamičkog zagrevanja, osnovnih vežbi koje su fokusirane na povećanje mišićne eksplozivnosti, snage mišića donjih ekstremiteta i snage mišića trupa i sekundarnih vežbi koje imaju za cilj poboljšanje fundamentalnih motoričkih veština. Kontrolna grupa imala je tradicionalni čas fizičkog vaspitanja, takođe dva puta nedeljno. Nakon uvodnih ~15 minuta učenici eksperimentalne grupe su realizovali identične aktivnosti kao kontrolna grupa u glavnom i završnom delu časa. U cilju evaluacije efekata eksperimentalnog i kontrolnog programa, primenjene su se sledeće baterije testova: za procenu motoričkih veština Test of Gross Motor Development, za procenu komponenti fizičke forme povezane sa zdravljem Fitnessgram i za procenu funkcionalne pokretljivosti Functional Movement System. U cilju utvrđivanja kvantitativnih efekata eksperimentalnog i kontrolnog programa primenjena je kombinovana analiza varijanse za ponovljena merenja. Za praćenje napretka grupe kao statistička mera koristila se veličina efekta. Rezultati istraživanja ukazali su na efikasnost integrisanih neuromišićnih vežbi na časovima fizičkog vaspitanja. Nakon primenjenih programa, na osnovu dobijenih rezultata uočile su se veće promene kod eksperimentalne grupe u odnosu na kontrolnu grupu u pojedinim varijablama motoričkih veština, fizičke forme povezane sa zdravljem i funkcionalne pokretljivosti." ]
[ "Тhe current study aims to determine the effects of eight-week integrated neuromuscular exercise implemented during physical education class in a primary school in lower elementary children on motor skills, health-related physical fitness, and functional movement. The study began in September 2019 and was completed in December in the same year. The sample consisted of 137 second-grade students of the elementary school \"Prva vojvodjanska brigada\" from Novi Sad (72 girls and 65 boys). Classes were randomly divided into the two groups: the intervention group (N = 60) and the control group (N = 77). The intervention group performed the integrated neuromuscular training program two times per week within the first ~15 min of physical education class consisting of a dynamic warm-up, basic exercises focused on increasing muscle strength and power, and secondary exercises focused on improving fundamental motor skills. The control group performed traditional physical education classes, also twice a week. After the initial 15 min, the intervention group performed the same activities as the control group in the main and final part of the class. To evaluate the effects of the experimental and control program, the following test batteries were used: for the assessment of motor skills Test of Gross Motor Development, for the assessment of health-related fitness components Fitnessgram, and for the assessment of functional movement Functional Movement System. Мixed model analysis of variance with repeated measures was used to evaluate the quantitative effects of the experimental and control program. The effect size was used as a statistical measure to monitor the progress of the group. The results of the study indicate the efficiency of integrated neuromuscular exercises in physical education classes. After the applied programs, based on the obtained results, considerable changes of the intervention group are noticed in comparison with the control group in certain variables of motor skills, health-related fitness, and functional movement are noticed." ]
sr (cyrillic script)
Univerzitet u Novom Sadu, Fakultet sporta i fizičkog vaspitanja u Novom Sadu
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Новом Саду
[ "интегрисан неуромишићни тренинг", "integrisan neuromišićni trening", "физичко васпитање", "млађи школски узраст", "моторичке вештине", "физичка форма", "функционална покретљивост", "fizičko vaspitanje", "mlađi školski uzrast", "motoričke veštine", "fizička forma", "funkcionalna pokretljivost" ]
[ "Integrated neuromuscular training", "physical education", "lower elementary", "motor skills", "physical fitness", "functional movement" ]
[ "Ефекти интегрисаног неуромишићног вежбања у настави физичког васпитања" ]
[ "Efekti integrisanog neuromišićnog vežbanja u nastavi fizičkog vaspitanja", "Effects of integrated neuromuscular exercise in physical education classes" ]
doctoralThesis
[ "BY-NC-ND" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/153763/Izvestaj_komisije_14037.pdf", "http://nardus.mpn.gov.rs/bitstream/id/153762/Disertacija_14037.pdf", "https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija162212424619666.pdf?controlNumber=(BISIS)117848&fileName=162212424619666.pdf&id=17852&source=NaRDuS&language=sr" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_21744" ]
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https://nardus.mpn.gov.rs/handle/123456789/10282
123456789-10282.pdf
yes
no
https://fedorabg.bg.ac.rs/fedora/get/o:18953/bdef:Content/download
yes
Sinteza i karakterizacija vatrostalnih materijala na bazi volframa
Synthesis and caracterisation of tungsteen based refractory materials
[ "Volkov Husović, Tatjana" ]
[ "Matović, Branko", "Kijevčanin, Mirjana", "Radović, Ivona", "Zagorac, Jelena" ]
Luković, Jelena
2018-12-10T11:47:14
[ "2018-12-10T11:47:14", "2020-07-03T09:24:51" ]
2018-09-29
[ "https://nardus.mpn.gov.rs/handle/123456789/10282", "http://eteze.bg.ac.rs/application/showtheses?thesesId=6296", "https://fedorabg.bg.ac.rs/fedora/get/o:18953/bdef:Content/download", "http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=50783247" ]
[ "Ideja ove doktorske disertacije je pronalaženje optimalnih uslova sinteze vatrostalnih materijala na bazi volframa: volfram karbida (WC) i volframovih silicida (volfram disilicida - WSi2, i pentavolfram trisilicida W5Si3) od elementarnih prahova..." ]
[ "The focus of this doctoral dissertation is finding the optimal parameters for the synthesis of tungsten-based refractory materials: tungsten carbide (WC) and tungsten silicides (tungsten disilicide-wSi2, and pentatungsten trisilicide - W5Si3) starting fom the elementary powders..." ]
application/pdf
sr
Универзитет у Београду, Технолошко-металуршки факултет
[ "info:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/45012/RS//" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Београду
[ "WC", "WSi2", "W5Si3", "rendgenska difraktometrija praha", "spark plazma sinterovanje", "nanoindentacija", "kavitaciona erozija" ]
[ "WC", "WSi2", "W5Si3", "X-ray powder diffractometry", "spark plasma sintering", "nanoindentation", "cavitation erosion" ]
[ "Sinteza i karakterizacija vatrostalnih materijala na bazi volframa" ]
[ "Synthesis and caracterisation of tungsteen based refractory materials" ]
doctoralThesis
[ "BY-NC-ND" ]
[ "https://nardus.mpn.gov.rs/bitstream/id/18611/Disertacija.pdf", "https://nardus.mpn.gov.rs/bitstream/id/18612/IzvestajKomisije18478.pdf", "http://nardus.mpn.gov.rs/bitstream/id/18611/Disertacija.pdf", "http://nardus.mpn.gov.rs/bitstream/id/18612/IzvestajKomisije18478.pdf", "https://fedorabg.bg.ac.rs/fedora/get/o:18953/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_10282" ]
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https://nardus.mpn.gov.rs/handle/123456789/21733
123456789-21733.pdf
yes
no
https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija167895835168364.pdf?controlNumber=(BISIS)128474&fileName=167895835168364.pdf&id=21547&source=NaRDuS&language=sr
no
Estetizacija u savremenom arhitektonskom diskursu: dualitet priređenog i autentičnog
Aestheticization in contemporary architectural discourse: the dualism ofstaged and authentic
[ "Atanacković-Jeličić, Jelena", "Rapaić, Milan" ]
[ "Dinulović, Radivoje", "Maraš, Igor", "Nikezić, Ana", "Atanacković-Jeličić, Jelena", "Rapaić, Milan" ]
Ćaćić, Marija
2023-10-04T13:58:24
[ "2023-10-04T13:58:24" ]
2023-07-07
[ "https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija167895835168364.pdf?controlNumber=(BISIS)128474&fileName=167895835168364.pdf&id=21547&source=NaRDuS&language=sr", "https://www.cris.uns.ac.rs/record.jsf?recordId=128474&source=NaRDuS&language=sr", "https://www.cris.uns.ac.rs/DownloadFileServlet/IzvestajKomisije167895840365132.pdf?controlNumber=(BISIS)128474&fileName=167895840365132.pdf&id=21548&source=NaRDuS&language=sr", "https://nardus.mpn.gov.rs/handle/123456789/21733" ]
[ "Arhitektonska stvarnost, koja se suočava sa nezaustavljivim rastom prostorne problematike, ,,dobar prostor’’ svodi na dobar proizvodni dizajn na globalnom tržištu estetskih senzacija. U vrtlogu estetizacije, koja posredstvom digitalnih kognitivnih stimulacija zahvata i arhitektonski prostor, dodatno zabrinjava što se u projektantskoj metodologiji nedovoljno tretira svakodnevni život korisnika u prostoru. S obzirom na nužnost sagledavanja arhitektonskog prostora i ljudskog života u sprezi, problemsko pitanje se pozicionira između estetičkih imaginacija konceptualnog i etičkih zahtjeva svakodnevnog prostora. Inicijalna pretpostavka je da arhitektonski prostor determiniše dualizam - dvojstvo različitih stanja prostora, koji imaju različite uticaje na percepciju posmatrača, odnosno na svakodnevni život korisnika. Taj dualizam priređenog (renderovanog) i autentičnog (svakodnevnog) prostora ispoljava sve učestalije konfliktan odnos, što dovodi u pitanje poziciju njihovog zajedničkog činioca - koncepta prostora. Glavna hipoteza rada ispituje da li masovna produkcija estetizovanih slika heterotopijskog života, zarobljena u domenu okularnih senzacija, uzrokuje zanemarivanje suštinskih prostorno-egzistencijalih interesa čovjeka i narušava autoritativnost arhitektonskog koncepta, prevodeći ga u manir. Sinteza zaključaka kulturološkog, konceptualnog, estetskog i fenomenološkog percipiranja prostora, koja uključuje relevantna teorijska mišljenja, stavove anketiranih fokusnih grupa (projektanata, korisnika i posmatrača prostora) i rezultate numeričkog eksperimenta sprovedenog putem dubokog mašinskog učenja (korišćenjem neuronske mreže), daće doprinos u razmatranju prostora kao života, a ne puke materijalne pojavnosti." ]
[ "Within the unstoppable growth of spatial issues, good space turns into attractive product design in the global market of aesthetic sensations. While aestheticization attacks the space through digital cognitive stimulation, it is upsetting that the everyday life is insufficiently treated in the architectural design. With the necessity of considering the space and life in conjunction, the research question is placed between the aesthetic imaginations of the conceptual and ethical requirements of the everyday. The initial hypothesis is that architectural space is determined by dualism of different modalities, which affect the spectator’s perception and the dweller’s everyday life. That dualism of staged and authentic space manifests an increasingly conflicting relationship, which makes questionable their common element - the concept of space. Research aim is to show whether the mass production of aestheticized images of heterotopian life, as ocular sensations, causes the neglect of the spatial and existential interests of users and disrupts the authoritativeness of the architectural concept, translating it into a manner. Synthesis of the conclusions of cultural, conceptual, aesthetic and phenomenological perception of space, which includes relevant theories, answers of surveyed focus groups (architects, users and observers of the space) and the results of a numerical experiment conducted through deep machine learning (using neural networks) - all together will contribute to the consideration of space as life, and not mere material appearance." ]
sr (latin script)
Универзитет у Новом Саду, Факултет техничких наука
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Новом Саду
[ "estetizacija", "koncept", "svakodnevni život", "dualitet" ]
[ "aestheticization", "concept", "everyday space", "duality" ]
[ "Estetizacija u savremenom arhitektonskom diskursu: dualitet priređenog i autentičnog" ]
[ "Aestheticization in contemporary architectural discourse: the dualism ofstaged and authentic" ]
doctoralThesis
[ "BY-NC-ND" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/153729/Disertacija_14061.pdf", "http://nardus.mpn.gov.rs/bitstream/id/153730/Izvestaj_komisije_14061.pdf", "https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija167895835168364.pdf?controlNumber=(BISIS)128474&fileName=167895835168364.pdf&id=21547&source=NaRDuS&language=sr" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_21733" ]
[ "" ]
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[ "" ]
[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/21739
123456789-21739.pdf
yes
no
https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija168449772525272.pdf?controlNumber=(BISIS)130161&fileName=168449772525272.pdf&id=21735&source=NaRDuS&language=sr
no
Funkcije prostora modernizma u transformaciji savremenog grada
Functions of modernist space in transformation of contemporary city
[ "Konstantinović, Dragana", "Peško, Igor" ]
[ "Zekovic, Miljana", "Pejić, Sonja", "Vuja, Aleksandru", "Konstantinović, Dragana", "Peško, Igor" ]
Jović, Slobodan
2023-10-04T13:58:34
[ "2023-10-04T13:58:34" ]
2023-09-04
[ "https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija168449772525272.pdf?controlNumber=(BISIS)130161&fileName=168449772525272.pdf&id=21735&source=NaRDuS&language=sr", "https://www.cris.uns.ac.rs/record.jsf?recordId=130161&source=NaRDuS&language=sr", "https://www.cris.uns.ac.rs/DownloadFileServlet/IzvestajKomisije168449775244913.pdf?controlNumber=(BISIS)130161&fileName=168449775244913.pdf&id=21736&source=NaRDuS&language=sr", "https://nardus.mpn.gov.rs/handle/123456789/21739" ]
[ "Predmet istraživanja u ovoj doktorskoj disertaciji je analiza istorijskog toka modernizacijskog procesa međuratnog i posleratnog perioda 20. veka i njegove refleksije na urbani prostor Novog Sada. Dubinskim istraživanjem ključnih prostora nastalim u procesu modernizacije, kao i razumevanjem svih mehanizama koji su ga oblikovali, možemo prepoznati potencijal ovih prostora da aktivno učestvuju u transformaciji savremenog grada. Zajednička ravan u kojem se grupiše dubinsko razumevanje modernističkog prostora i njegovog potencijala instrumentalizacije u savremenom trenutku definiše se kroz pojam modernizacijski metakod. On predstavlja suštinsku indentifikaciju modernističkog prostora s modernizacijskim potencijalom, a koji se uspostavlja kroz vrednosne kriterijume obrazložene u ovom radu. Dubinskim razumevanjem modernističkog prostora možemo pozitivno uticati na društvenu percepciju ovog značajnog elementa naše urbane sredine. Sve to bi doprinelo i boljem razumevanju celovite slike istorije urbanog razvoja Novog Sada, a samim tim bi se stvorila i kvalitetnija osnova za promišljanje budućeg razvoja grada." ]
[ "The subject of this doctoral dissertation is the analysis of the historical course of the modernization process in the interwar and post-war period of the 20th century and its reflection on the urban space of Novi Sad. By in-depth research of key spaces created in the process of modernization, as well as understanding all the mechanisms that shaped it, we can recognize the potential of these spaces to actively participate in the transformation of the contemporary city. The common ground of an in-depth understanding of modernist space and its potential for instrumentalization is defined through the term metacode of modernization. It represents an essential identification of the modernist space with modernization potential, which is established through the value criteria explained in this thesis. By better understanding of modernist space, we can positively influence the social perception of this significant element of our urban environment. All this would contribute to a better understanding of the complete picture of the history of urban development of Novi Sad, and thus create a better basis for thinking about the future development of the city." ]
sr (latin script)
Универзитет у Новом Саду, Факултет техничких наука
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc/4.0/" ]
Универзитет у Новом Саду
[ "modernizam", "modernistički prostor", "modernizacija Novog Sada", "Novkabel", "Bulevar 23. oktobra", "Mišeluk", "modernizacijski metakod", "arhitektonske tipologije" ]
[ "Modernism", "modernist space", "modernization of Novi Sad", "Novkabel", "Bulevar 23. oktobra", "Mišeluk", "metacode of modernization", "architectural typology" ]
[ "Funkcije prostora modernizma u transformaciji savremenog grada" ]
[ "Functions of modernist space in transformation of contemporary city" ]
doctoralThesis
[ "BY-NC" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/153748/Izvestaj_komisije_14071.pdf", "http://nardus.mpn.gov.rs/bitstream/id/153747/Disertacija_14071.pdf", "https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija168449772525272.pdf?controlNumber=(BISIS)130161&fileName=168449772525272.pdf&id=21735&source=NaRDuS&language=sr" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_21739" ]
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https://nardus.mpn.gov.rs/handle/123456789/21728
123456789-21728.pdf
yes
no
https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija169078985470998.pdf?controlNumber=(BISIS)132293&fileName=169078985470998.pdf&id=21924&source=NaRDuS&language=sr
no
Примена форсинг методе на доказивање комбинаторних тврђења
Primena forsing metode na dokazivanje kombinatornih tvrđenja
[ "Kurilić, Miloš", "Todorčević, Stevo" ]
[ "Šobot, Boris", "Kurilić, Miloš", "Todorčević, Stevo", "Kuzeljević, Boriša", "Perović, Aleksandar" ]
Стефановић, Недељко
2023-10-04T13:57:45
[ "2023-10-04T13:57:45" ]
2023-09-29
[ "https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija169078985470998.pdf?controlNumber=(BISIS)132293&fileName=169078985470998.pdf&id=21924&source=NaRDuS&language=sr", "https://www.cris.uns.ac.rs/record.jsf?recordId=132293&source=NaRDuS&language=sr", "https://www.cris.uns.ac.rs/DownloadFileServlet/IzvestajKomisije169078986166147.pdf?controlNumber=(BISIS)132293&fileName=169078986166147.pdf&id=21925&source=NaRDuS&language=sr", "https://nardus.mpn.gov.rs/handle/123456789/21728" ]
[ "Пол Коен је конструисао модел за који је доказао да у њему важе ZF аксиоме, али не и аксиома избора. Ипак, Халперн и Леви су доказали да у том моделу важи BPI (исказ да свака Булова алгебра има ултрафилтер). Тај доказ се темељи на Халперн Лојхлијевој теореми, која представља ремзијевско тврђење о бојењу производа дрвета. Касније је Харингтон пронашао далеко једноставнији доказ Халперн Лојхлијеве теореме коришћењем форсинга. Касније су пронађене многе друге примене Халперн-Лојхлијеве теореме. Овде се Халперн-Лојхлијева теорема изводи из чињенице да у Коеновом иметричном моделу моделу важи BPI и показује се како се тај модел може користити уместо Халперн-Лојхлијеве теореме за доказивање тврђења која се иначе доказују применом Халперн-Лојхлијеве теореме. Другим речима, даје се метода која представља алтернативу Халперн Лојхлијевој теореми у њеним применама, при чему тај апарат има исту снагу као Халперн-Лојхлијева теорема. Та метода је апстрахован у виду теореме која важи у ZFC и у чијој формулацији нема метаматематичких појмова. Такође, дају се још неке замене за Халперн-Лојхлијеву теорему, које нису доказиве у ZFC, али које су апсолутне за одређену класу тврђења. Применом једне од теорема апсолутности из овог текста се добија алтернативни доказ Халперн-Лојхлијеве теореме. Наводе се и могућности примене изложених теорема апсолутности у теорији пољских простора и математичкој анализи. Такође, дата је одговарајућа теорема која важи у ZFC и у чијој формулацији нема метаматематичких појмова.", "Pol Koen je konstruisao model za koji je dokazao da u njemu važe ZF aksiome, ali ne i aksioma izbora. Ipak, Halpern i Levi su dokazali da u tom modelu važi BPI (iskaz da svaka Bulova algebra ima ultrafilter). Taj dokaz se temelji na Halpern Lojhlijevoj teoremi, koja predstavlja remzijevsko tvrđenje o bojenju proizvoda drveta. Kasnije je Harington pronašao daleko jednostavniji dokaz Halpern Lojhlijeve teoreme korišćenjem forsinga. Kasnije su pronađene mnoge druge primene Halpern-Lojhlijeve teoreme. Ovde se Halpern-Lojhlijeva teorema izvodi iz činjenice da u Koenovom imetričnom modelu modelu važi BPI i pokazuje se kako se taj model može koristiti umesto Halpern-Lojhlijeve teoreme za dokazivanje tvrđenja koja se inače dokazuju primenom Halpern-Lojhlijeve teoreme. Drugim rečima, daje se metoda koja predstavlja alternativu Halpern Lojhlijevoj teoremi u njenim primenama, pri čemu taj aparat ima istu snagu kao Halpern-Lojhlijeva teorema. Ta metoda je apstrahovan u vidu teoreme koja važi u ZFC i u čijoj formulaciji nema metamatematičkih pojmova. Takođe, daju se još neke zamene za Halpern-Lojhlijevu teoremu, koje nisu dokazive u ZFC, ali koje su apsolutne za određenu klasu tvrđenja. Primenom jedne od teorema apsolutnosti iz ovog teksta se dobija alternativni dokaz Halpern-Lojhlijeve teoreme. Navode se i mogućnosti primene izloženih teorema apsolutnosti u teoriji poljskih prostora i matematičkoj analizi. Takođe, data je odgovarajuća teorema koja važi u ZFC i u čijoj formulaciji nema metamatematičkih pojmova." ]
[ "Paul Cohen constructed a model (Cohen's symmetric model) for which he proved that the axioms of ZF hold in it, but not the Axiom of Choice. Nevertheless, Halpern and Levy proved in that in the Cohen's symmetric model BPI (the statement that every Boolean algebra has an ultrafilter) is true. That proof was based on the Halpern-Läuchli theorem, a Ramsey-Theoretic proposition about the partitioning of tree products. Later, Harrington found another proof of the Halpern-Läuchli theorem using forcing. Later, many other applications of the Halpern-Läuchli theorem were found \\cite{rs}. Here, Halpern-Läuchli theorem is derived from the fact that BPI holds in the Cohen's symmetric model, and it is shown how that model can be used instead of the Halpern-Läuchli theorem to prove statements which are otherwise proved by applying the theorem. In other words, a mathematical method is given. That method is an alternative to the Halpern-Läuchli theorem in its applications, whereby that method has the same power as the theorem itself. This method is abstracted by ZFC theorem without metamathematical notions in formulation. Also, a relative consistency with ZFC, of some principles which are stronger than the Halpern-Läuchli theorem, is given. This provides a new proof of the Halpern-Läuchli theorem from the axioms of ZFC. Corresponded ZFC theorem without metamathematical notions in formulation is also given." ]
sr (cyrillic script)
Универзитет у Новом Саду, Природно-математички факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Новом Саду
[ "Форсинг, Ремзијева теорија, Комбинаторика", "Forsing, Remzijeva teorija, Kombinatorika" ]
[ "Forcing, Ramsey theory, combinatorics" ]
[ "Примена форсинг методе на доказивање комбинаторних тврђења" ]
[ "Primena forsing metode na dokazivanje kombinatornih tvrđenja", "Applications of the forcing method to proving combinatorial theorems" ]
doctoralThesis
[ "BY-NC-ND" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/153714/Disertacija_14079.pdf", "http://nardus.mpn.gov.rs/bitstream/id/153715/Izvestaj_komisije_14079.pdf", "https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija169078985470998.pdf?controlNumber=(BISIS)132293&fileName=169078985470998.pdf&id=21924&source=NaRDuS&language=sr" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_21728" ]
[ "" ]
[ "" ]
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https://nardus.mpn.gov.rs/handle/123456789/21734
123456789-21734.pdf
yes
no
https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija167965379758568.pdf?controlNumber=(BISIS)128793&fileName=167965379758568.pdf&id=21560&source=NaRDuS&language=sr
no
Модел управљања просторно – временским подацима у паметном граду
Model upravljanja prostorno – vremenskim podacima u pametnom gradu
[ "Govedarica, Miro" ]
[ "Stojanović, Dragan", "Jakovljević, Gordana", "Sladić, Dubravka", "Radulović, Aleksandra", "Govedarica, Miro" ]
Amović, Mladen
2023-10-04T13:58:26
[ "2023-10-04T13:58:26" ]
2023-07-14
[ "https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija167965379758568.pdf?controlNumber=(BISIS)128793&fileName=167965379758568.pdf&id=21560&source=NaRDuS&language=sr", "https://www.cris.uns.ac.rs/record.jsf?recordId=128793&source=NaRDuS&language=sr", "https://www.cris.uns.ac.rs/DownloadFileServlet/IzvestajKomisije167965380719210.pdf?controlNumber=(BISIS)128793&fileName=167965380719210.pdf&id=21561&source=NaRDuS&language=sr", "https://nardus.mpn.gov.rs/handle/123456789/21734" ]
[ "У концепту паметних градова, користе се различите дигиталне технологије које пружају могућности прикупљања и процесирања геопросторних података. У том смислу потребно је податке добијене различитим технологијама, међусобно интегрисати у јединствену цјелину која је идентификована smart city концептом. Сходно томе, потребно је управљати структуираним, полуструктуираним и неструктуираним подацима. Успостављање система управљања који ће пружити могућности јединствене интеграције подразумијева потребу за рјешавањем тзв. 5V проблема. Проблеми система за управљање подацима се углавном се односе на: количину (volume) , различитост (variety), брзина (velocity), варијабилност (varibility) и вриједност (value). Предмет истраживања подразумијева успостављање новог концепта система управљања великим серијама просторно – временских података у оквиру паметног града који ће бити заснован на Big Data концепту трансформације, складиштења и процесирања геоподатака. Концепт користи приступ у рјешавању проблема употребом Big Data алгоритама паралелизације процеса, који обезбјеђују значајно боље перформансе система. Предложени модел је biG dAta sMart cIty maNagEment SyStem (GAMINESS). Moдел управљања великим серијама просторно – временских података у контексту паметног града обезбијеђује: идентификацију стандарда под којим се врши дистрибуција података, прикупљање геоподатака који су у структуираној, полуструктуираној и неструктуираној форми, увођење комплексних типова података у потпуности заснованих на Big Data програмском окружењу Apache Spark, аутоматизоване процедуре превођења геоподатака у структуирану форму, успостављање интегралног система складиштења и управљања геоподацима и систем децентрализованог одлучивања у геосензорском пакету.", "U konceptu pametnih gradova, koriste se različite digitalne tehnologije koje pružaju mogućnosti prikupljanja i procesiranja geoprostornih podataka. U tom smislu potrebno je podatke dobijene različitim tehnologijama, međusobno integrisati u jedinstvenu cjelinu koja je identifikovana smart city konceptom. Shodno tome, potrebno je upravljati struktuiranim, polustruktuiranim i nestruktuiranim podacima. Uspostavljanje sistema upravljanja koji će pružiti mogućnosti jedinstvene integracije podrazumijeva potrebu za rješavanjem tzv. 5V problema. Problemi sistema za upravljanje podacima se uglavnom se odnose na: količinu (volume) , različitost (variety), brzina (velocity), varijabilnost (varibility) i vrijednost (value). Predmet istraživanja podrazumijeva uspostavljanje novog koncepta sistema upravljanja velikim serijama prostorno – vremenskih podataka u okviru pametnog grada koji će biti zasnovan na Big Data konceptu transformacije, skladištenja i procesiranja geopodataka. Koncept koristi pristup u rješavanju problema upotrebom Big Data algoritama paralelizacije procesa, koji obezbjeđuju značajno bolje performanse sistema. Predloženi model je biG dAta sMart cIty maNagEment SyStem (GAMINESS). Model upravljanja velikim serijama prostorno – vremenskih podataka u kontekstu pametnog grada obezbijeđuje: identifikaciju standarda pod kojim se vrši distribucija podataka, prikupljanje geopodataka koji su u struktuiranoj, polustruktuiranoj i nestruktuiranoj formi, uvođenje kompleksnih tipova podataka u potpunosti zasnovanih na Big Data programskom okruženju Apache Spark, automatizovane procedure prevođenja geopodataka u struktuiranu formu, uspostavljanje integralnog sistema skladištenja i upravljanja geopodacima i sistem decentralizovanog odlučivanja u geosenzorskom paketu." ]
[ "" ]
sr (cyrillic script)
Универзитет у Новом Саду, Факултет техничких наука
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc/4.0/" ]
Универзитет у Новом Саду
[ "Модел управљања паметним градом", "Model upravljanja pametnim gradom", "геопросторни Big Data", "Apache Spark SQL", "Сензори", "IoT", "geoprostorni Big Data", "Apache Spark SQL", "Senzori", "IoT" ]
[ "Smart City", "Geospatial Big Data", "Apache Spark SQL", "Sensors", "IoT" ]
[ "Модел управљања просторно – временским подацима у паметном граду" ]
[ "Model upravljanja prostorno – vremenskim podacima u pametnom gradu", "Мanagement System of Smart City in the context of Big Data" ]
doctoralThesis
[ "BY-NC" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/153733/Izvestaj_komisije_14062.pdf", "http://nardus.mpn.gov.rs/bitstream/id/153732/Disertacija_14062.pdf", "https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija167965379758568.pdf?controlNumber=(BISIS)128793&fileName=167965379758568.pdf&id=21560&source=NaRDuS&language=sr" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_21734" ]
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https://nardus.mpn.gov.rs/handle/123456789/21745
123456789-21745.pdf
yes
no
https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija162212562551834.pdf?controlNumber=(BISIS)117851&fileName=162212562551834.pdf&id=17856&source=NaRDuS&language=sr
no
Preventivni programi i njihovo profilaktičko dejstvo kod sprinterskog trčanja
Prevention programmes and their prophylactic effects on sprint
[ "Mihajlović, Ilona" ]
[ "Vasić, Goran", "Juhas, Irina", "Molnar, Slavko" ]
Đinić, Ivan
2023-10-04T14:01:12
[ "2023-10-04T14:01:12" ]
2021-09-13
[ "https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija162212562551834.pdf?controlNumber=(BISIS)117851&fileName=162212562551834.pdf&id=17856&source=NaRDuS&language=sr", "https://www.cris.uns.ac.rs/record.jsf?recordId=117851&source=NaRDuS&language=sr", "https://www.cris.uns.ac.rs/DownloadFileServlet/IzvestajKomisije162212563615283.pdf?controlNumber=(BISIS)117851&fileName=162212563615283.pdf&id=17857&source=NaRDuS&language=sr", "https://nardus.mpn.gov.rs/handle/123456789/21745" ]
[ "Uzorak od 30 ispitanika muškog pola, uzrasta od 15 do 21 godinu, atletičara koji su bili u redovnom trenažnom procesu, podeljen je u dve grupe, kontrolnu i ekperimentalnu, a na drugoj je sproveden kompezatorni i preventivni program, čiji je cilj bio jačanje, istezanje i korekcija antagonističke muskulature, uglavnom rizičnih područja povređivanja atletičara. Cilj ovog istraživanja je bio da se utvrdi uticaj različitih preventivnih i kompezatornih programa na zdravlje atletičara na kraju tromesečnog (dvanaestonedeljnog) eksperimetalnog tretmana i poboljšanje ili pogoršanje brzine trčanja u odnosu na napredak ili pogoršanje u varijablama sprinta kod kontrolne grupe. Metrijske karakteristike testova su pokazale dobre i zadovoljavajuće vrednosti, a multivarijatna analiza kovarijanse (MANCOVA) je testirala razlike 4 manifestne varijable sprinterske brzine između eksperimetalne i kontrolne grupe i ukazala da postoje statistički značajne razlike između ispitanika različitih grupa u varijablama sprinterskog trčanja u korist eksperimentalne." ]
[ "The sample of 30 male athletes, aged 15 to 21 years old, all of them included in regular training process, were divided into two groups – control and experimental. Compensatory and preventive programs were applied in experimental group, and their aim was to strength, stretch and correct antagonist muscle groups, mainly injury risk areas of track and field athletes. The aim of the research was to determine influence of different compensatory and preventive programs on athlete’s health and speed development regarding both groups at the end of the 12 weeks (three months) experiment. Internal metric characteristics of all tests were good and satisfactory and the results of Multivariate analysis of covariance (MANCOVA) tested the differences of 4 sprint variables between control and experimental groups and suggested that there is statistically significant difference in values of variables between subjects of different groups of athletes in favor of experimental group." ]
sr (latin script)
Univerzitet u Novom Sadu, Fakultet sporta i fizičkog vaspitanja u Novom Sadu
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Новом Саду
[ "sprinterska brzina", "atletika", "uticaj prevencije povreda", "zadnja loža", "pregibači kuka", "kičmeni stub" ]
[ "sprinting", "athletics", "track and field", "effects of injury prevention", "hamstring", "hip flexor", "vertebral column" ]
[ "Preventivni programi i njihovo profilaktičko dejstvo kod sprinterskog trčanja" ]
[ "Prevention programmes and their prophylactic effects on sprint" ]
doctoralThesis
[ "BY-NC-ND" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/153766/Izvestaj_komisije_14038.pdf", "http://nardus.mpn.gov.rs/bitstream/id/153765/Disertacija_14038.pdf", "https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija162212562551834.pdf?controlNumber=(BISIS)117851&fileName=162212562551834.pdf&id=17856&source=NaRDuS&language=sr" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_21745" ]
[ "" ]
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https://nardus.mpn.gov.rs/handle/123456789/7867
123456789-7867.pdf
yes
no
https://fedorabg.bg.ac.rs/fedora/get/o:15035/bdef:Content/download
no
Модификатори девербативних именица
Modifiers of deverbal nouns ; Модификаторы сушествитрлых производные от глаголов
[ "Kovačević, Borko" ]
[ "" ]
Nerandžić-Čanda, Lidija P.
2017-04-10T13:55:57
[ "2017-04-10T13:55:57", "2020-07-03T12:45:14" ]
2016-09-01
[ "https://nardus.mpn.gov.rs/handle/123456789/7867", "http://eteze.bg.ac.rs/application/showtheses?thesesId=4763", "https://fedorabg.bg.ac.rs/fedora/get/o:15035/bdef:Content/download", "http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=48768783" ]
[ "Предмет овог рада јесте морфолошко – синтаксичка и делом семантичка анализа девербативних именица у савременом српском језку. Будући да неке класе девербативних именица, а на првом месту праве глаголске именице, могу да поседују синтаксичке и семантичке особине које се преклапају са синтаксичким и семантичким особинама глагола од којих су настале, истражили смо како се понашају модификатори оваквих именица. Рад се бави анализом и класификацијом модификатора девербативних именица, као и описом окружења у ком се појављују, односно њиховом дистрибуцијом уз девербативне именице. Посебно занимљиво питање, због глаголског порекла ових именица, јесте утврђивање именичког/глаголског карактера њихових модификатора, односно да ли се уз девербативне именице, и уз које класе ових именица, појављују изразито именички модификатори, или и неки изразито глаголски модификатори. Корпус је ексцерпиран из две врсте извора. Први извор су електронски медији у писаном облику (pescanik.net, www.e-novine.com, htp://blog.b92.net) a поједине примере из електронских издања дневне штампе преузели смо из Корпуса савременог српског језика Математичког факултета у Београду. Други извор грађе чине примери из ,,Знакова поред пута“ Ива Андрића, као репрезента књижевног језика. Издвојени модификатори су табеларно разврстани на врсте речи, односно на тип јединице и њено лексичко језгро, затим на конституентски облик, а потом на синтаксичку функцију." ]
[ "The subject of this paper is morphological - syntactic and partly semantic analysis of deverbal nouns in the modern Serbian Language. Since some classes of deverbal nouns, firstly real gerund, may own a syntactic and semantic characteristics that overlap with syntactic and semantic properties of the verb from which they originate, we investigated behavior of the modifiers of these nouns. The paper is about the analysis and classification of modifiers of deverbal nouns of the context in which they appear, and their distribution with deverbal nouns. Particularly interesting question, simply because of the origin of these verbal nouns, is to determinate noun/verbal character of the modifiers, i.e. whether distinctive noun modifiers appear with deverbal nouns or some extreme verbal modifiers and with what classes of these nouns. Corpus was is excepionated from two types of sources. The first source is electronic media in written form (pescanik.net, www.e- novine.com, htp://blog.b92.net) and some examples are taken from the electronic edition of daily newspapers taken from the Corpus of Contemporary Serbian language from the Faculty of Mathematics in Belgrade. The second source consist of examples from “Signs by the Roadside” Ivo Andric, as a representative of the literary language. Featured modifiers are tabulated based on word classes i.e. type of unit, its lexical nucleus, the constituent form, and syntactic function." ]
application/pdf
sr
Универзитет у Београду, Филолошки факултет
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by/4.0/" ]
Универзитет у Београду
[ "модификатори", "девербативне именице", "тип јединице", "конституенски облик", "синтаксичка функција" ]
[ "modifiers", "deverbal nouns", "type unit", "constituent form", "syntactic function" ]
[ "Модификатори девербативних именица" ]
[ "Modifiers of deverbal nouns ; Модификаторы сушествитрлых производные от глаголов" ]
doctoralThesis
[ "BY" ]
Ковачевић, Борко; Неранджић-Чанда, Лидија П.; Modifikatori deverbativnih imenica;
[ "https://nardus.mpn.gov.rs/bitstream/id/32376/Disertacija.pdf", "https://nardus.mpn.gov.rs/bitstream/id/32377/IzvestajKomisije8166.pdf", "http://nardus.mpn.gov.rs/bitstream/id/32376/Disertacija.pdf", "http://nardus.mpn.gov.rs/bitstream/id/32377/IzvestajKomisije8166.pdf", "https://fedorabg.bg.ac.rs/fedora/get/o:15035/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_7867" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
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[ "" ]
[ "" ]
[ "" ]
[ "" ]
https://nardus.mpn.gov.rs/handle/123456789/21750
123456789-21750.pdf
yes
no
http://nardus.mpn.gov.rs/bitstream/id/153780/Disertacija_14080.pdf
no
Efekti različitih formulacija kreatina na motoričko-funkcionalne sposobnosti, biohemijske markere i energetiku mišića i mozga rekreativnih sportista
Effects of different creatine formulations on exercise performance, biochemistry and muscle and brain tissue bioenergetics in recreational athletes
[ "Ostojić, Sergej" ]
[ "Drid, Patrik", "Vraneš, Milan", "Valdemar, Štajer" ]
Semeredi, Saša
2023-10-04T14:01:17
[ "2023-10-04T14:01:17" ]
2023-09-27
[ "https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija169096184142248.pdf?controlNumber=(BISIS)132437&fileName=169096184142248.pdf&id=21932&source=NaRDuS&language=sr", "https://www.cris.uns.ac.rs/record.jsf?recordId=132437&source=NaRDuS&language=sr", "https://www.cris.uns.ac.rs/DownloadFileServlet/IzvestajKomisije169096187949283.pdf?controlNumber=(BISIS)132437&fileName=169096187949283.pdf&id=21933&source=NaRDuS&language=sr", "https://nardus.mpn.gov.rs/handle/123456789/21750" ]
[ "Uvod: Kreatin predstavlja intenzivno istraživano, efikasno ergogeno sredstvo koje dovodi do povećanja ćelijskih rezervi kreatina. Poslednjih decenija suplementacija guanidinosirćetnom kiselinom (GAA) predstavljena je kao superiorno sredstvo za unapređenje ćelijske bioenergetike u odnosu na kreatin i alternativno rešenje kojim bi se uspešno otklonili eventualni nedostaci suplementacije kreatinom. Cilj ovog istraživanja jeste utvrđivanje efekata kombinovanog unosa kreatina i GAA na antropometrijski status, apsolutnu (maksimalnu), eksplozivnu i repetitivnu snagu, kardiorespiratornu izdržljivost, kao i biohemijske i indikatore tkivno-ćelijske bioenergetike kod zdravih muškaraca koji se rekreativno bave sportom. Materijali i metode: U istraživanju je učestvovalo 14 muškaraca starosti između 18 i 30 godina (telesna visina 176,49±7,25 cm; telesna masa 79,86±13,86 kg), koji se bace sportom 5 i više sati nedeljno i poseduju višegodišnje trenažno iskustvo u različitim tipovima aktivnosti. Studija je organizovana kao randomizirana, dvostruko slepa, cross-over studija kontrolisana kreatinom. Eksperimentalna grupa unosila je kombinaciju kreatina i GAA (3 g Cr + 1 g GAA) tokom 4 nedelje, dok je kontrolna grupa konzumirala ekvimolarnu količinu kreatina (4 g Cr). Nakon završetka tretmana i wash out perioda (4 nedelje), grupe su zamenile tretmane. Dnevna doza suplementacije podrazumevala je unos praha rastvorenog u 250 ml mlake vode nakon noćnog gladovanja, pre doručka. Inicijalno, te nakon završetka svake faze, sprovedena su antropometrijska merenja, biohemijske analize, testovi motoričko-funkcionalnih sposobnosti i magnetna spektroskopija četvoroglavog mišića natkolenice i sive i bele moždane mase. Rezultati: Tretman kreatinom doveo je do statistički značajnog povećanja telesne mase u odnosu na inicijalno merenje (79,86±13,86 kg vs 81,48±13,22 kg; p=0,01), dok ove razlike nisu utvrđene nakon tretmana Cr+GAA (80,6±13,68 kg; p>0,05). Značajno povećanje vrednosti Cr u serumu uočeno je u obe grupe (inicijalno 20,87±5,3 μM/L vs Cr 44,45±16,53 μM/L; p=0.001, i Cr+GAA 39,83±12,37 μM/L; p=0,001), pri čemu nisu uočene značajne razlike između tretmana (p>0,05). Povećanje vrednosti Crn u serumu nakon tretmana nije statistički potvrđeno (p>0,05). Vrednosti Crn bile su niže pre unosa suplementacije u odnosu na Cr+GAA grupu (84±89 μM/L vs 88,45±6,44 μM/L), dok je unos kreatina doveo do dodatnog povećanja (90,51±12,56 μM/L). Vrednosti GAA i tHcy u serumu nisu se značajno razlikovale nakon oba nutritivna tretmana uodnosu na inicijalno merenje (p>0,05). Unos suplementacije doveo je do statistički značajnog povećanja vrednosti snage. U testu potisak sa ravne klupe sa slobodnim tegovima (BP) vrednosti su porasle nakon unosa kreatina (97,08±23,67 kg vs 101,67±22,7 kg; p=0,003), te dodatno nakon kombinacije Cr+GAA (102,92±25,71 kg; p=0,004). U testu prednji čučanj statistički značajno povećanje vrednosti snage utvrđeno je nakon oba tretmana (inicijalno 107,5±15,3 kg vs Cr 122,5±10,55 kg; p<0,00 i Cr+GAA 121,25±8,29 kg; p<0,001), dok razlike između grupa nisu statistički potvrđene (p>0,05). U testu skok iz stojećeg stava sa zamahom rukama (VJ) uočeno je statistički značajno smanjenje visine skoka nakon tretmana kreatinom (57,06±6,02 cm vs 53,88±5,17 cm; p>0,001) i tretmana Cr+GAA (54,86±4,88 cm; p=0,006) u odnosu na inicijalno merenje. Kombinacija Cr i GAA dovela je do statistički značajnog porasta kreatina u interesnoj regiji sive moždane mase (Z=-2,02; p=0,043), ali ne i tretman kreatinom zasebno (p>0,05). Tretman Cr+GAA doveo je do povećanja vrednosti kreatina za dodatnih 4,0% u odnosu na kreatin (inicijalno 8,94±0,77 mM vs Cr 9,09±0,93 mM; Cr+GAA 9,45±0,7 mM). Povećanje vrednosti kreatina u interesnoj regiji bele moždane mase nakon unosa suplementacije nije statistički potvrđeno (p>0,05), ipak unos kreatina doveo je do povećanja od 7,0% u odnosu na inicijalno merenje (7,60±0,63 mM vs 8,22±0,52 mM), a tretman Cr+GAA je ostvario dodatno poećanje od 6,3% u odnosu na tretman kreatinom (8,74±1,13 mM). Kombinacija Cr i GAA ostvarila je dodatno povećanje vrednosti Cr u četvoroglavom mišiću natkolenice od 13,1% u odnosu na unos kreatina zasebno (inicijalno 35,53±5,86 mM vs Cr 36,03±4,91 mM; Cr+GAA 40,74±3,45 mM). Zaključak: Kombinacija kreatina i GAA u odnosu 3:1 potvrdila se kao superioran tretman za unapređenje ćelijskih rezervi kreatina u mišićnom i moždanom tkivu u odnosu na kreatin. Nova formulacija kreatina dovela je do značajnog povećanja snage gornjih i donjih ekstremiteta, praćenog značajno manjim povećanjem telesne mase u odnosu na kreatin, nakon 4-nedeljnog tretmana kod zdravih, fizički aktivnih muškaraca. Istraživani tretman značajno je umanjio rizik od hiperhomocisteinemije u odnosu na unos GAA zasebno." ]
[ "Introduction: Creatine is a well-recognized, effective ergogenic agent that leads to an increase in cellular creatine reserves. In recent years, guanidinoacetic acid (GAA) supplementation has been presented as a superior treatment for tackling cellular bioenergetic compared to creatine, and an alternative solution that could eliminate potential shortcomings of creatine. The aim of this study is to determine the effects of combined intake of creatine and GAA on anthropometric status, maximal, explosive and repetitive strength, aerobic endurance, as well as biochemical and indicators of tissue bioenergetics in healthy, well-trained men. Methods: 14 men between ages 18 and 30 (height 176.49±7.25 cm; body mass 79.86±13.86 kg) engaged in different physical activities for 5 or more hours per week participated in this research. In this randomized, double-blind, creatine-controlled cross-over study, the experimental group ingested a combination of creatine and GAA (3 g Cr + 1g GAA) for 4 weeks. The control group consumed an equimolar dose of creatine (4 g Cr) per day. Upon the end of the first phase and wash-out period (4 weeks), the groups switched treatments to ensure between-subjects comparison. The daily dose included the intake of the powder dissolved in 250 ml of lukewarm water immediately after night fasting. Anthropometric measurements, biochemical analyses, functional ability tests, and magnetic spectroscopy of muscle and brain tissue were conducted initially, as well as after the completion of each research phase. Results: Creatine treatment led to a statistically significant increase in body weight compared to the initial measurement (79,86±13,86 kg vs 81,48±13,22 kg; p=0,01), while these differences were not determined after Cr+GAA treatment (80,6±13,68 kg; p>0,05). A significant increase in Cr serum levels was observed in both groups (initial 20,87±5,3 μM/L vs Cr 44,45±16,53 μM/L; p=0.001, and Cr+GAA 39,83±12,37 μM/L; p=0,001), and no significant differences were observed between treatments (p>0,05). The increase in Crn serum levels was not statistically confirmed after treatments (p>0,05). Crn values were lower before supplementation compared to the Cr+GAA group (84±89 μM/L vs 88,45±6,44 μM/L), while creatine intake led to an additional increase (90,51±12,56 μM/L). Additionally, GAA and tHcy serum values did not differ significantly after both nutritional treatments compared to the initial measurement (p>0,05). Supplementation led to a statistically significant increase in strength. In the bench press, the values increased after creatineintake (97,08±23,67 kg vs 101,67±22,7 kg; p=0,003), and additionally after the Cr+GAA combination (102,92±25,71 kg; p=0,004). In the front squat, a statistically significant increase in strength was observed after both treatments (initial 107,5±15,3 kg vs Cr 122,5±10,55 kg; p<0,00 and Cr+GAA 121,25±8,29 kg; p<0,001), while the differences between treatments were not statistically confirmed (p>0,05). In the vertical jump, a statistically significant decrease in jump height was observed after creatine treatment (57,06±6,02 cm vs 53,88±5,17 cm; p>0,001), and Cr+GAA treatment (54,86±4,88 cm; p=0,006) compared to initial values. Furthermore, the combination of Cr and GAA led to a statistically significant increase in gray matter creatine levels (Z=-2,02; p=0,043), but not creatine treatment alone (p>0,05) compared to initial values. Cr+GAA led to an increase in creatine levels by an additional 4,0% compared to creatine (initial 8,94±0,77 mM vs Cr 9,09±0,93 mM; Cr+GAA 9,45±0,7 mM). The increase in white matter creatine levels was not statistically confirmed after the supplementation intake (p>0,05), however, the creatine intake led to an increase of 7,0% compared to the initial measurement (7,60±0,63 mM vs 8,22±0,52 mM), and the Cr+GAA treatment led to an additional increase of 6,3% compared to creatine alone (8,74±1,13 mM). The Cr+GAA combination achieved an additional 13,1% increase in creatine levels in m. vastus medialis compared to creatine intake alone (initial 35,53±5,86 mM vs Cr 36,03±4,91 mM; Cr+GAA 40,74±3,45 mM). Conclusion: The combination of creatine and GAA in a 3:1 ratio proved to be a superior treatment for improving the cellular creatine reserves in muscle and brain tissue compared to creatine alone. A new creatine formulation produced significant increases in upper and lower body strength, accompanied by significantly less weight gain compared to creatine after 4-weeks treatment in healthy, physically active men. The investigated treatment significantly reduced the risk of hyperhomocysteinemia compared to GAA intake alone." ]
sr (latin script)
Univerzitet u Novom Sadu, Fakultet sporta i fizičkog vaspitanja u Novom Sadu
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Новом Саду
[ "Guanidinosirćetna kiselina", "kreatin", "suplementacija" ]
[ "Guanidinoacetic acid", "creatine", "supplementation" ]
[ "Efekti različitih formulacija kreatina na motoričko-funkcionalne sposobnosti, biohemijske markere i energetiku mišića i mozga rekreativnih sportista" ]
[ "Effects of different creatine formulations on exercise performance, biochemistry and muscle and brain tissue bioenergetics in recreational athletes" ]
doctoralThesis
[ "BY-NC-ND" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/153780/Disertacija_14080.pdf", "http://nardus.mpn.gov.rs/bitstream/id/153781/Izvestaj_komisije_14080.pdf", "https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija169096184142248.pdf?controlNumber=(BISIS)132437&fileName=169096184142248.pdf&id=21932&source=NaRDuS&language=sr" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_21750" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
[ "" ]
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https://nardus.mpn.gov.rs/handle/123456789/21740
123456789-21740.pdf
yes
no
http://nardus.mpn.gov.rs/bitstream/id/153750/Disertacija_14072.pdf
no
Предлог за уштеду меморијских ресурса у алгоритму коначних разлика у временском домену коришћењем аритметике у блоковском покретном зарезу
Predlog za uštedu memorijskih resursa u algoritmu konačnih razlika u vremenskom domenu korišćenjem aritmetike u blokovskom pokretnom zarezu
[ "Kaštelan, Ivan" ]
[ "Teslić, Nikola", "Popović, Miroslav", "Pjevalica, Nebojša", "Vranješ, Mario", "Kaštelan, Ivan" ]
Pijetlović, Stefan
2023-10-04T13:58:36
[ "2023-10-04T13:58:36" ]
2023-08-28
[ "https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija168482708274812.pdf?controlNumber=(BISIS)130166&fileName=168482708274812.pdf&id=21744&source=NaRDuS&language=sr", "https://www.cris.uns.ac.rs/record.jsf?recordId=130166&source=NaRDuS&language=sr", "https://www.cris.uns.ac.rs/DownloadFileServlet/IzvestajKomisije168482710012017.pdf?controlNumber=(BISIS)130166&fileName=168482710012017.pdf&id=21745&source=NaRDuS&language=sr", "https://nardus.mpn.gov.rs/handle/123456789/21740" ]
[ "Докторска теза анализира предлог за уштеду меморијских ресурса у меморијски интензвином алгоритму. Предмет истраживања је проналажење решења које би услед ефикаснијег руковања меморијом имало и мању потрошњу исте што би резултовало ефикаснијим системом и решењем. Резултат истраживања је симулација која потрвђује хипотезу, као и физичка имплементација која проверава исправност концепта.", "Doktorska teza analizira predlog za uštedu memorijskih resursa u memorijski intenzvinom algoritmu. Predmet istraživanja je pronalaženje rešenja koje bi usled efikasnijeg rukovanja memorijom imalo i manju potrošnju iste što bi rezultovalo efikasnijim sistemom i rešenjem. Rezultat istraživanja je simulacija koja potrvđuje hipotezu, kao i fizička implementacija koja proverava ispravnost koncepta." ]
[ "PhD thesis analyzes a proposal for improving memory bandwidth in a memory intense algorithm. The purpose of the study is to find a more effective and efficient solution which would use less memory for the same algorithm and thus have better performance. The result of the study is a simulation model which proves the hypothesis as well as a hardware implementation on an FPGA development board which acts as a proof of concept." ]
sr (cyrillic script)
Универзитет у Новом Саду, Факултет техничких наука
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc/4.0/" ]
Универзитет у Новом Саду
[ "Меморијски интензивни проблеми", "Memorijski intenzivni problemi", "aritmetika u blokovskom pokretnom zarezu", "algoritam konačnih razlika u vremenskom domenu (FDTD)", "FPGA", "аритметика у блоковском покретном зарезу", "алгоритам коначних разлика у временском домену (FDTD)", "FPGA" ]
[ "Memory intense problems", "Block floating-point arithmetic", "Finite-Difference TimeDomain (FDTD)", "FPGA" ]
[ "Предлог за уштеду меморијских ресурса у алгоритму коначних разлика у временском домену коришћењем аритметике у блоковском покретном зарезу" ]
[ "Predlog za uštedu memorijskih resursa u algoritmu konačnih razlika u vremenskom domenu korišćenjem aritmetike u blokovskom pokretnom zarezu", "Improving finite-difference time-domain memory bandwidth by using block floating-point arithmetic" ]
doctoralThesis
[ "BY-NC" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/153751/Izvestaj_komisije_14072.pdf", "http://nardus.mpn.gov.rs/bitstream/id/153750/Disertacija_14072.pdf", "https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija168482708274812.pdf?controlNumber=(BISIS)130166&fileName=168482708274812.pdf&id=21744&source=NaRDuS&language=sr" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_21740" ]
[ "" ]
[ "" ]
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https://nardus.mpn.gov.rs/handle/123456789/21746
123456789-21746.pdf
yes
no
http://nardus.mpn.gov.rs/bitstream/id/153768/Disertacija_14039.pdf
no
Model za povećanje eksplozivne snage donjih ekstremiteta kod adolescenata
Model for increasing the explosive power of the lower limbs in adolescents
[ "Mihajlović, Ilona" ]
[ "Obradović, Borislav", "Dimitrić, Goran", "Juhas, Irina" ]
Radulovic, Nikola
2023-10-04T14:01:13
[ "2023-10-04T14:01:13" ]
2021-09-09
[ "https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija162222961454254.pdf?controlNumber=(BISIS)117855&fileName=162222961454254.pdf&id=17866&source=NaRDuS&language=sr", "https://www.cris.uns.ac.rs/record.jsf?recordId=117855&source=NaRDuS&language=sr", "https://www.cris.uns.ac.rs/DownloadFileServlet/IzvestajKomisije16222296243151.pdf?controlNumber=(BISIS)117855&fileName=16222296243151.pdf&id=17867&source=NaRDuS&language=sr", "https://nardus.mpn.gov.rs/handle/123456789/21746" ]
[ "Cilj ovog istraživanja bio je da se utvrde efekti petnaestonedeljnog ekperimentalnog tretmana na motoričke sposobnosti ispitanika koji su činili studenti Univerziteta u Novom Sadu, uzrasta 20-21 godine. Nakon podele celokupnog uzorka, eksperimentalnu grupu je činilo 48, dok je kontrolnu grupu činilo 53 ispitanika. Ispitanici iz eksperimentalne grupe bili su podvrgnuti petnaestonedeljnom eksperimentalnom tretmanu u vidu kompleksnog treniga, koji je bio sproveden 3x nedeljno, dok su se ispitanici kontrolne grupe uz svakodnevne aktivnosti obavezno bavili sportskorekreativnim aktivnostima 2-3 puta nedeljno. Razlike između grupa na inicijalnom i finalnom merenju utvrđene su pomoću multivarijatne analize varijasne (MANOVA), univarijatne analize varijanse (ANOVA) i diskriminativne analize, za sve tretirane varijable. Za utvrđivanje efekta primenjenog eksperimentalnog tretmana (trenažnog modela), primenjena je multivarijatna analiza kovarijanse (MANCOVA), za ceo sistem primenjenih varijabli, dok je pojedinačna razlika kod analiziranih varijabli utvrđena primenom univarijatne analize kovarijanse (ANCOVA). U prvom delu analizirane su razlike motoričkih varijabli, dok su u drugom delu prikazane razlike varijabli eksplozivne snage donjih ekstremiteta. Nakon sprovedenog eksperimentalnog tretmana, a na osnovu rezultata multivarijatne analize kovarijanse, može se zaključiti da postoji statistički značajna razlika između ispitanika E i K grupe u motoričkim varijablama (p = .000), kao i uvarijablama eksplozivne snage (p= .000). Na osnovu svega, može se zaključiti da je primenjeni eksperimentalni tretman bio uspešan i dao željene efekte na poboljšanje ciljanih motoričkih sposobnosti." ]
[ "The aim of this study was to determine the effects that a fifteen-week experimental treatment has on the motor abilities of respondents who were students of the University of Novi Sad, aged 20-21 years. After dividing the entire sample, the experimental group consisted of 48, while the control group consisted of 53 respondents. Respondents from the experimental group were subjected to a fifteen-week experimental treatment in the form of complex training, which was conducted 3 times a week, while the respondents of the control group were engaged in daily sports and recreational activities 2-3 times a week. Differences between the groups regarding initial and final results were determined using multivariate analysis of variance (MANOVA), univariate analysis of variance (ANOVA) and discriminant analysis, for all treated variables. To determine the effect of the applied experimental treatment (training model), multivariate covariance analysis (MANCOVA) was applied for the whole system of applied variables, while the individual difference in the analyzed variables was determined using univariate covariance analysis (ANCOVA). The first part analyzes the differences of motor variables, while the second part presents the differences of the explosive power variables of the lower extremities. After the conducted experimental treatment, and based on the results of multivariate analysis of covariance, it can be concluded that there is a statistically significant difference between respondents of E and C groups in motor variables (p = .000), as well as in explosive power variables (p =.000). Based on all this, it can be concluded that the applied experimental treatment was successful and gave the desired effects on the improvement of target motor abilities." ]
sr (latin script)
Univerzitet u Novom Sadu, Fakultet sporta i fizičkog vaspitanja u Novom Sadu
[ "" ]
[ "openAccess" ]
[ "" ]
Универзитет у Новом Саду
[ "Eksperiment", "eksplozivna snaga", "kompleksni trening", "motoričke sposobnosti" ]
[ "Experiment", "explosive power", "complex training", "motor abilities" ]
[ "Model za povećanje eksplozivne snage donjih ekstremiteta kod adolescenata" ]
[ "Model for increasing the explosive power of the lower limbs in adolescents" ]
doctoralThesis
[ "Attribution-NonCommercial-ShareAlike" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/153769/Izvestaj_komisije_14039.pdf", "http://nardus.mpn.gov.rs/bitstream/id/153768/Disertacija_14039.pdf", "https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija162222961454254.pdf?controlNumber=(BISIS)117855&fileName=162222961454254.pdf&id=17866&source=NaRDuS&language=sr" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_21746" ]
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https://nardus.mpn.gov.rs/handle/123456789/21751
123456789-21751.pdf
yes
no
http://nardus.mpn.gov.rs/bitstream/id/153783/Disertacija_14081.pdf
no
Rehabilitacioni tretman nakon operacije prednjeg ukrštenog ligamenta sa izokinetičkim i izotoničkim vežbanjem
Rehabilitation Treatment After Anterior Cruciate Ligament Surgery with Isokinetic and Isotonic Exercises
[ "Obradović, Borislav" ]
[ "Drid, Patrik", "Bubanj, Saša", "Šćepanović, Tijana" ]
Nikolić, Siniša M.
2023-10-04T14:01:19
[ "2023-10-04T14:01:19" ]
2023-09-29
[ "https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija169096272455030.pdf?controlNumber=(BISIS)132440&fileName=169096272455030.pdf&id=21936&source=NaRDuS&language=sr", "https://www.cris.uns.ac.rs/record.jsf?recordId=132440&source=NaRDuS&language=sr", "https://www.cris.uns.ac.rs/DownloadFileServlet/IzvestajKomisije169096863054620.pdf?controlNumber=(BISIS)132440&fileName=169096863054620.pdf&id=21938&source=NaRDuS&language=sr", "https://nardus.mpn.gov.rs/handle/123456789/21751" ]
[ "Generalni cilj ovog istraņivanja je da se uporede uĉinci izokinetiĉkog i izotoniĉkog vjeņbanja na rezultate rehabilitacije pacijenata tri mjeseca nakon hirurńke rekonstrukcije prednjeg ukrńtenog ligamenta. Analiziran je uzorak od 180 ispitanika podijeljen u dva subuzorka u odnosu na vrstu rehabilitacionog tretmana koji je provoĊen. Ispitivanu grupu A-izokinetiĉku saĉinjavalo je 90 muńkih ispitanika, prosjeĉne starosti 28.54±4.44 godina. Kod njih je rehabilitacioni protokol bio zasnovan na izokinetiĉkom vjeņbanju natkoljenih mińića. Ispitivanu grupu B-izotoniĉku (klasiĉnu) saĉinjavalo je 90 muńkih ispitanika, prosjeĉne starosti 27.93±4.27 godina. Kod ovih ispitanika se u rehabilitacionom protokolu za jaĉanje natkoljene muskulature primjenjivao program vjeņbanja sa dodatnim otporom, tj. izotoniĉko vjeņbanje u trenaņnoj sali. Prije poĉetka rehabilitacionog tretmana uraĊen je inicijalni izokinetiĉki test pri ugaonoj brzini od 60°/s kod svih ispitanika. Nakon tri i ńest sedmica rehabilitacionog tretmana raĊeni su kontrolni testovi istim naĉinom i prateći iste parametre kao i na inicijalnom testu. Na osnovu vrijednosti analize MANOVA i analize DISKRIMINATIVNA, naĊeni su znaĉajno bolji rezultati izokinetiĉkih testova u ispitivanoj grupi A - izokinetiĉkoj u odnosu na ispitivanu grupu B - izotoniĉku. Razlika izmeĊu ispitivanih grupa je bila znaĉajnija na finalnom mjerenju nakon ńest sedmica rehabilitacionog tretmana u odnosu na kontrolno mjerenje nakon tri sedmice tetmana. Na osnovu dobijenih rezultata istraņivanja zakljuĉujemo da je izokinetiĉko vjeņbanje djelotvornije po pitanju rehabilitacije natkoljenih mińića nakon rekonstrukcije prednjeg ukrńtenog ligamenta." ]
[ "General aim of this study is to compare the effects of isokinetic and isotonic exercise on the rehabilitation results in patients three months after surgical reconstruction of the anterior cruciate ligament. A sample of 180 subjects was analyzed, divided into two subsamples in relation to the type of rehabilitation treatment that was performed. The examined group A-isokinetic, consisted of 90 male subjects, at the average age of 28.54±4.44. Their rehabilitation protocol was based on isokinetic exercise of the upper leg muscles. The examined group B-isotonic (classical), consisted of 90 male subjects, at average age of 27.93±4.27. In the case of these subjects, an exercise program with additional resistance was applied in the rehabilitation protocol for strengthening the lower leg muscles, i.e. isotonic exercise in the gym. Before the start of the rehabilitation treatment, an initial isokinetic test was performed at an angular velocity of 60°/s in all subjects. After three and six weeks of rehabilitation treatment, control tests were performed in the same way and the same parameters were followed as in the initial test. Based on the values of MANOVA analysis and DISCRIMINATIVE analysis, significantly better results of isokinetic tests were found in the examined group A – isokinetic, compared to the examined group B –isotonic. The difference between the examined groups was more significant at the final measurement after six weeks of rehabilitation treatment compared to the control measurement after three weeks of testing. Based on the results of the research, we conclude that isokinetic exercise is more effective in terms of rehabilitation of the lower leg muscles after the reconstruction of the anterior cruciate ligament." ]
sr (latin script)
Univerzitet u Novom Sadu, Fakultet sporta i fizičkog vaspitanja u Novom Sadu
[ "" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc/4.0/" ]
Универзитет у Новом Саду
[ "izokinetiĉko vežbanje", "izotoniĉko vežbanje", "izokinetiĉko testiranje", "rekonstrukcija ACL" ]
[ "isokinetic exercise", "isotonic exercise", "isokinetic testing", "ACL reconstruction" ]
[ "Rehabilitacioni tretman nakon operacije prednjeg ukrštenog ligamenta sa izokinetičkim i izotoničkim vežbanjem" ]
[ "Rehabilitation Treatment After Anterior Cruciate Ligament Surgery with Isokinetic and Isotonic Exercises" ]
doctoralThesis
[ "BY-NC" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/153784/Izvestaj_komisije_14081.pdf", "http://nardus.mpn.gov.rs/bitstream/id/153783/Disertacija_14081.pdf", "https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija169096272455030.pdf?controlNumber=(BISIS)132440&fileName=169096272455030.pdf&id=21936&source=NaRDuS&language=sr" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_21751" ]
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https://nardus.mpn.gov.rs/handle/123456789/10283
123456789-10283.pdf
yes
no
https://fedorabg.bg.ac.rs/fedora/get/o:18966/bdef:Content/download
no
Sinteza, funkcionalizacija i primena aktivnih ugljeničnih mikro i nano materijala
Synthesis, functionalization and application of activated carbon micro and nano materials
[ "Marinković, Aleksandar" ]
[ "Kaluđerović, Branka", "Uskoković, Petar", "Radojević, Vesna", "Stojmenović, Marija" ]
Krstić, Sanja
2018-12-10T11:47:14
[ "2018-12-10T11:47:14", "2020-07-03T09:19:49" ]
2018-09-28
[ "http://eteze.bg.ac.rs/application/showtheses?thesesId=6308", "https://nardus.mpn.gov.rs/handle/123456789/10283", "https://fedorabg.bg.ac.rs/fedora/get/o:18966/bdef:Content/download", "http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=50778127" ]
[ "Predmet istraživanja ove doktorske disertacije bio je sinteza, usavršavanje i primena novih ugljeničnih materijala optimalnih adsorpcionih i tehno-ekonomskih karakteristika korišćenjem hidrotermalne metode sinteze, kao i ispitivanje uticaja aktivacije na krajnja svojstva i mogućnost primene dobijenih materijala. Hidrotermalnom metodom se, iz saharida kao polaznih materijala, sintetizuju „hidročađi”, materijali koji sadrže veći udeo ugljenika od saharida, ali nisu aktivni. Naknadnom aktivacijom hidročađi, korišćenjem različitih hidroksida, dobijaju se aktivirani ugljenični materijali. Dobijeni aktivirani ugljenični materijali ispitivani su u oblasti zaštite životne sredine kao adsorbenti u sistemima za uklanjanje teških metala i zagađujućih boja (metilen plave i metil oranž) iz otpadnih voda. Takođe, ispitivane su termijske osobine dobijenih materijala za primenu u sistemima za skladištenje električne energije. Uticaj parametara hidrotermalne sinteze i uslova aktivacije sintetizovanih materijala ispitivan je variranjem temperature hidrotermalnog procesa, vremena zadržavanja i koncentracije vodenog rastvora polaznog materijala kao i promenom temperature i vrste aktivacije, aktivirajućeg agensa i odnosa količine aktivirajućeg agensa i materijala koji se aktivira. Izvršena je karakterizacija dobijenih uzoraka aktiviranih ugljeničnih materijala, različitih fizičkih i površinskih osobina, na osnovu kojih je izvršen odabir najefikasnijeg uzorka za uklanjanje datih zagađivača iz životne sredine. Postupak sinteze aktiviranih ugljeničnih materijala sastojao se od pripreme materijala hidrotermalnom obradom vodenih rastvora saharida (fruktoze, glukoze i saharoze) pri blagim uslovima (na 160, 200 i 240 °C), a potom mehanohemijskom aktivacijom dobijene hidročađi uz pomoć KOH, NaOH i LiOH i poređenjem dobijenih rezultata..." ]
[ "The subject of the research of the presented doctoral dissertation was synthesis, improvement and application of active carbon materials of optimal adsorption and techno-economic characteristics, obtained by hydrothermal method. Also, the influence of activation on the final properties and the possibility active carbon materials application have been studied. The synthesis of active carbon materials was carried out applying hydrothermal method using saccharides as starting materials, which represent the first step in the synthesis process. In this step, carbon containing samples were derived, but they had no active properties. Carbon containing materials obtained after hydrothermal process were called \"hydrochar\". Afterwards, they were activated by chemical activation process with various hydroxides, and final samples with specified active features were synthesized. The application of activated carbon materials was found in the field of environmental protection as an adsorbent in the systems with heavy metal and polluting dyes removal from wastewater. Testing of thermal properties of materials for use in electrical energy storage systems was also investigated. In order to examine the influence of the parameters of both the hydrothermal method and activation process, experiments were conducted by varying following parameters: temperature of hydrothermal process, starting material, retention time, concentration of the aqueous solution of the starting material as well as type of activation agent. Carbon materials samples of different physical and surface characteristics were characterized and the most efficient sample was selected for removal of given environmental pollutants. The process of synthesis of activated carbon materials consisted of the preparation of the material by hydrothermal treatment of aqueous solutions of saccharides (fructose, glucose and sucrose) under gentle conditions (at 160, 200 and 240 ° C), followed by mechanochemical activation by three hydroxides KOH, NaOH and LiOH and comparison of obtained results were examined..." ]
application/pdf
sr
Универзитет у Београду, Технолошко-металуршки факултет
[ "info:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/45005/RS//" ]
[ "openAccess" ]
[ "https://creativecommons.org/licenses/by-nc-nd/4.0/" ]
Универзитет у Београду
[ "aktivni ugljenik", "hidrotermalna metoda", "saharidi", "mehanohemijska aktivacija hidroksidima", "adsorpcija teških metala", "uklanjanje boja" ]
[ "active carbon", "hydrothermal method", "saccharides", "mechanochemical activation by hydroxides", "heavy metal adsorption", "toxic dyes removal" ]
[ "Sinteza, funkcionalizacija i primena aktivnih ugljeničnih mikro i nano materijala" ]
[ "Synthesis, functionalization and application of activated carbon micro and nano materials" ]
doctoralThesis
[ "BY-NC-ND" ]
[ "http://nardus.mpn.gov.rs/bitstream/id/17332/IzvestajKomisije18490.pdf", "https://nardus.mpn.gov.rs/bitstream/id/17331/Disertacija.pdf", "https://nardus.mpn.gov.rs/bitstream/id/17332/IzvestajKomisije18490.pdf", "http://nardus.mpn.gov.rs/bitstream/id/17331/Disertacija.pdf", "https://fedorabg.bg.ac.rs/fedora/get/o:18966/bdef:Content/download" ]
[ "https://hdl.handle.net/21.15107/rcub_nardus_10283" ]
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