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ARTICLE VII. A CASE OF ELEPHANTIASIS SUCCESSFUL RECOVERY. By R. DEXTER, M.D., Chicago. Carrie G., cet. 20, an inmate of the Erring Women's Refuge, gives the following history of herself and the outgrowth': Is a native of Rochester, N.Y.; has resided in the southern part of Illinois several years. A little more than a year ago, she observed that the external labia were somewhat increased in size, and presented an unusually rough appearance. The rapid growth of the parts induced her to seek medical advice. The external application of iodine was prescribed, together with the exhibition of internal remedies, but without any beneficial results. The advice of another physician was sought, but change of treatment brought no relief. Our attention was called to the case about two months since. Found the external labia enormously hypertrophied, presenting every appearance and symptom of elephantiasis. Each lip was about five inches long, and one and a-balf inches through. It seemed that but one alternative remained, viz.: excision. The counsel of a medical gentleman was obtained, who fully in the opinions above given. Accordingly, on the 21st of December last, we removed the entire mass. Hemorrhage was controlled during the operation by tying the arteries as they were divided. There were four on each side, but were not enlarged. Recovery will be perfect, with but trifling deformity. |
Methodist Debakey Cardiovasc J Methodist Debakey Cardiovasc J 1947-6108 Methodist DeBakey Cardiovascular Journal 1947-6094 1947-6108 Houston Methodist DeBakey Heart & Vascular Center 10.14797/mdcvj.1216 VoR Dr. Phil's Art Corner Happy Childhood Alexander Philip MD [email protected] 1 1 College Station, Texas, US CORRESPONDING AUTHOR: Philip Alexander, MD College Station, Texas, US [email protected] 07 3 2023 2023 19 2 107108 08 2 2023 08 2 2023 Copyright: (c) 2023 The Author(s) 2023 This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC-BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. See Philip Alexander, MD, is a native Texan, retired physician, and accomplished musician and artist. After 41 years as an internal medicine physician, Dr. Phil retired from his practice in College Station in 2016. A lifelong musician and former music professor, he often performs as an oboe soloist for the Brazos Valley Symphony Orchestra. He began exploring visual art in 1980, evolving from pencil sketches including an official White House portrait of President Ronald Reagan to the computer-generated drawings featured in this journal. His images, which first appeared in this journal in the spring of 2012, are his own original creations. If you would like to see your art published in the Methodist DeBakey Cardiovascular Journal, submit your creation online at journal.houstonmethodist.org as a "Humanities" entry. pmcImage 1 Sisters. Sisters Image 2 What Happy Looks Like! What Happy Looks Like! |
Erratum. In the haste of writing, on the first line of page 670, of The Journal, we inadvertently put down Henry instead of Hughes, as every one knows it should have been written. We beg J. Hughes Bennett's pardon. |
]) OR (Remote Sensing[Title/Abstract]) AND (Covid-19[Title/Abstract])) 55 55 (All relevant documents were duplicates from Scopus search) Scopus TITLE-ABS-KEY ((("satellite imaging") OR ("remote sensing")) AND ("COVID-19")) 597 292 Number of duplicate records: 52. Not articles: 253 (note, letter, review, short survey, book chapter, conference paper, conference review, editorial) Disclaimer/Publisher's Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content. |
bioRxiv BIORXIV bioRxiv Cold Spring Harbor Laboratory 10.1101/2023.02.26.530118 preprint 1 Article Novel Approach Explains Spatio-Spectral Interactions in Raw Electroencephalogram Deep Learning Classifiers Ellis Charles A. Sattiraju Abhinav Miller Robyn L. Calhoun Vince D. 27 2 2023 2023.02.26.530118 nihpp-2023.02.26.530118.pdf ABSTRACT The application of deep learning classifiers to resting-state electroencephalography (rs-EEG) data has become increasingly common. However, relative to studies using traditional machine learning methods and extracted features, deep learning methods are less explainable. A growing number of studies have presented explainability approaches for rs-EEG deep learning classifiers. However, to our knowledge, no approaches give insight into spatio-spectral interactions (i.e., how spectral activity in one channel may interact with activity in other channels). In this study, we combine gradient and perturbation-based explainability approaches to give insight into spatio-spectral interactions in rs-EEG deep learning classifiers for the first time. We present the approach within the context of major depressive disorder (MDD) diagnosis identifying differences in frontal d activity and reduced interactions between frontal electrodes and other electrodes. Our approach provides novel insights and represents a significant step forward for the field of explainable EEG classification. pmc |
bioRxiv BIORXIV bioRxiv Cold Spring Harbor Laboratory 10.1101/2023.02.26.530160 preprint 1 Article The Wolbachia WalE1 effector alters Drosophila endocytosis Martin MaryAnn Newton Irene L.G. 27 2 2023 2023.02.26.530160 nihpp-2023.02.26.530160.pdf Abstract The most common intracellular bacterial infection is Wolbachia pipientis , a microbe that manipulates host reproduction and is used in control of insect vectors. Phenotypes induced by Wolbachia have been studied for decades and range from sperm-egg incompatibility to male killing. How Wolbachia alters host biology is less well understood. Previously, we characterized the first Wolbachia effector aEUR" WalE1, which encodes a synuclein domain at the N terminus. Purified WalE1 sediments with and bundles actin and when heterologously expressed in flies, increases Wolbachia titer in the developing oocyte. In this work, we first identify the native expression WalE1 by Wolbachia infecting both fly cells and whole animals. WalE1 appears as aggregates, separate from Wolbachia cells. We next show that WalE1 co-immunoprecipitates with the host protein Past1 and that WalE1 manipulates host endocytosis. Yeast expressing WalE1 show deficiency in uptake of FM4-64 dye, and flies harboring mutations in Past1 or overexpressing WalE1 are sensitive to AgNO 3 , a hallmark of endocytosis defects. Finally, we also show that Past1 null flies harbor more Wolbachia overall and in late egg chambers. Our results identify interactions between a Wolbachia secreted effector and a host protein and point to yet another important host cell process impinged upon by Wolbachia . pmc |
bioRxiv BIORXIV bioRxiv Cold Spring Harbor Laboratory 10.1101/2023.02.27.530235 preprint 1 Article Continuous, long-term crawling behavior characterized by a robotic transport system Yu James Dancausse Stephanie Paz Maria Faderin Tolu Gaviria Melissa Shomar Joseph Zucker Dave Venkatachalam Vivek Klein Mason 28 2 2023 2023.02.27.530235 nihpp-2023.02.27.530235.pdf Abstract Detailed descriptions of behavior provide critical insight into the structure and function of nervous systems. In Drosophila larvae and many other systems, short behavioral experiments have been successful in characterizing rapid responses to a range of stimuli at the population level. However, the lack of long-term continuous observation makes it difficult to dissect comprehensive behavioral dynamics of individual animals and how behavior (and therefore the nervous system) develops over time. To allow for long-term continuous observations in individual fly larvae, we have engineered a robotic instrument that automatically tracks and transports larvae throughout an arena. The flexibility and reliability of its design enables controlled stimulus delivery and continuous measurement over developmental time scales, yielding an unprecedented level of detailed locomotion data. We utilize the new systemaEURTMs capabilities to perform continuous observation of exploratory behavior over a duration of six hours with and without a thermal gradient present, and in a single larva for over 30 hours. Long-term free-roaming behavior and analogous short-term experiments show similar dynamics that take place at the beginning of each experiment. Finally, characterization of larval thermotaxis in individuals reveals a bimodal distribution in navigation efficiency, identifying distinct phenotypes that are obfuscated when only analyzing population averages. pmc |
bioRxiv BIORXIV bioRxiv Cold Spring Harbor Laboratory 10.1101/2023.02.27.530195 preprint 1 Article Label-free differential imaging of cellular components in mouse brain tissue by wide-band photoacoustic microscopy Liu Yajing Wong Terence T W Shi Junhui He Yun Nie Liming Wang Lihong V. 28 2 2023 2023.02.27.530195 nihpp-2023.02.27.530195.pdf Abstract Mapping diverse cellular components with high spatial resolution is important to interrogate biological systems and study disease pathogenesis. Conventional optical imaging techniques for mapping biomolecular profiles with differential staining and labeling methods are cumbersome. Different types of cellular components exhibit distinctive characteristic absorption spectra across a wide wavelength range. By virtue of this property, a lab-made wide-band optical-resolution photoacoustic microscopy (wbOR-PAM) system, which covers wavelengths from the ultraviolet and visible to the shortwave infrared regions, was designed and developed to capture multiple cellular components in 300-mm-thick brain slices at nine different wavelengths without repetitive staining and complicated processing. This wbOR-PAM system provides abundant spectral information. A reflective objective lens with an infinite conjugate design was applied to focus laser beams with different wavelengths, avoiding chromatic aberration. The molecular components of complex brain slices were probed without labeling. The findings of the present study demonstrated a distinctive absorption of phospholipids, a major component of the cell membrane, brain, and nervous system, at 1690 nm and revealed their precise distribution with microscopic resolution in a mouse brain, for the first time. This novel imaging modality provides a new opportunity to investigate important biomolecular components without either labeling or lengthy specimen processing, thus, laying the groundwork for revealing cellular mechanisms involved in disease pathogenesis. pmc |
bioRxiv BIORXIV bioRxiv Cold Spring Harbor Laboratory 10.1101/2023.02.25.530046 preprint 2 Article Convolutional-recurrent neural networks approximate diffusion tractography from T1-weighted MRI and associated anatomical context Cai Leon Y Lee Ho Hin Newlin Nancy R. Kerley Cailey I. Kanakaraj Praitayini Yang Qi Johnson Graham W. Moyer Daniel Schilling Kurt G. Rheault Francois Landman Bennett A. 08 3 2023 2023.02.25.530046 nihpp-2023.02.25.530046.pdf Diffusion MRI (dMRI) streamline tractography is the gold-standard for in vivo estimation of white matter (WM) pathways in the brain. However, the high angular resolution dMRI acquisitions capable of fitting the microstructural models needed for tractography are often time-consuming and not routinely collected clinically, restricting the scope of tractography analyses. To address this limitation, we build on recent advances in deep learning which have demonstrated that streamline propagation can be learned from dMRI directly without traditional model fitting. Specifically, we propose learning the streamline propagator from T1w MRI to facilitate arbitrary tractography analyses when dMRI is unavailable. To do so, we present a novel convolutional-recurrent neural network (CoRNN) trained in a teacher-student framework that leverages T1w MRI, associated anatomical context, and streamline memory from data acquired for the Human Connectome Project. We characterize our approach under two common tractography paradigms, WM bundle analysis and structural connectomics, and find approximately a 5-15% difference between measures computed from streamlines generated with our approach and those generated using traditional dMRI tractography. When placed in the literature, these results suggest that the accuracy of WM measures computed from T1w MRI with our method is on the level of scan-rescan dMRI variability and raise an important question: is tractography truly a microstructural phenomenon, or has dMRI merely facilitated its discovery and implementation? pmc |
bioRxiv BIORXIV bioRxiv Cold Spring Harbor Laboratory 36909515 10.1101/2023.02.26.529821 preprint 2 Article Structural homology screens reveal poxvirus-encoded proteins impacting inflammasome-mediated defenses Boys Ian N. Johnson Alex G. Quinlan Meghan Kranzusch Philip J. Elde Nels C. 03 4 2023 2023.02.26.529821 nihpp-2023.02.26.529821.pdf Summary Viruses acquire host genes via horizontal gene transfer and can express them to manipulate host biology during infections. Some viral and host homologs retain sequence identity, but evolutionary divergence can obscure host origins. We used structural modeling to compare vaccinia virus proteins with metazoan proteomes. We identified vaccinia A47L as a homolog of gasdermins, the executioners of pyroptosis. An X-ray crystal structure of A47 confirmed this homology and cell-based assays revealed that A47 inhibits pyroptosis. We also identified vaccinia C1L as the product of a cryptic gene fusion event coupling a Bcl-2 related fold with a pyrin domain. C1 associates with components of the inflammasome, a cytosolic innate immune sensor involved in pyroptosis, yet paradoxically enhances inflammasome activity, suggesting a benefit to poxvirus replication in some circumstances. Our findings demonstrate the potential of structural homology screens to reveal genes that viruses capture from hosts and repurpose to benefit viral fitness. pmc |
bioRxiv BIORXIV bioRxiv Cold Spring Harbor Laboratory 10.1101/2023.02.27.530226 preprint 1 Article Detecting the effect of genetic diversity on brain composition in an Alzheimer's disease mouse model Gurdon Brianna Yates Sharon C. Csucs Gergely Groeneboom Nicolaas E. Hadad Niran Telpoukhovskaia Maria Ouellette Andrew Ouellette Tionna O'Connell Kristen Singh Surjeet Murdy Tom Merchant Erin Bjerke Ingvild Kleven Heidi Schlegel Ulrike Leergaard Trygve B. Puchades Maja A. Bjaalie Jan G. Kaczorowski Catherine C. 28 2 2023 2023.02.27.530226 nihpp-2023.02.27.530226.pdf Abstract Alzheimer's disease (AD) is characterized by neurodegeneration, pathology accumulation, and progressive cognitive decline. There is significant variation in age at onset and severity of symptoms highlighting the importance of genetic diversity in the study of AD. To address this, we analyzed cell and pathology composition of 14-month-old AD-BXD mouse brains using the semi-automated workflow (QUINT); which we expanded to allow for nonlinear refinement of brain atlas-registration, and quality control assessment of atlas-registration and brain section integrity. Near global age-related increases in microglia, astrocyte, and amyloid-beta accumulation were measured, while regional variation in neuron load existed among strains. Furthermore, hippocampal immunohistochemistry analyses were combined with bulk results to demonstrate the relationship between cell composition and gene expression. Overall, the additional functionality of the QUINT workflow delivers a highly effective method for registering and quantifying cell and pathology changes in diverse disease models. pmc |
bioRxiv BIORXIV bioRxiv Cold Spring Harbor Laboratory 10.1101/2023.02.27.530263 preprint 1 Article Ultrasensitive response explains the benefit of combination chemotherapy despite drug antagonism Patterson Sarah C. Pomeroy Amy E. Palmer Adam C. 27 2 2023 2023.02.27.530263 nihpp-2023.02.27.530263.pdf Abstract Most aggressive lymphomas are treated with combination chemotherapy, commonly as multiple cycles of concurrent drug administration. Concurrent administration is in theory optimal when combination therapies have synergistic (more than additive) drug interactions. We investigated pharmacodynamic interactions in the standard 4-drug 'CHOP' regimen in Peripheral T-Cell Lymphoma (PTCL) cell lines, and found that CHOP consistently exhibits antagonism and not synergy. We tested whether staggered treatment schedules could improve tumor cell kill by avoiding antagonism, using month-long in vitro models of concurrent or staggered treatments. Surprisingly, we observed that tumor cell kill is maximized by concurrent drug administration despite antagonistic drug-drug interactions. We propose that an ultrasensitive dose response, as described in radiology by the linear-quadratic (LQ) model, can reconcile these seemingly contradictory experimental observations. The LQ model describes the relationship between cell survival and dose, and in radiology has identified scenarios favoring hypofractionated radiation - the administration of fewer large doses rather than multiple smaller doses. Specifically, hypofractionated treatment can be favored when cells require an accumulation of DNA damage, rather than a 'single hit', in order to die. By adapting the LQ model to combination chemotherapy and accounting for tumor heterogeneity, we find that tumor cell kill is maximized by concurrent administration of multiple drugs, even when chemotherapies have antagonistic interactions. Thus, our study identifies a new mechanism by which combination chemotherapy can be clinically beneficial that is not reliant on positive drug-drug interactions. pmc |
bioRxiv BIORXIV bioRxiv Cold Spring Harbor Laboratory 10.1101/2023.02.27.529887 preprint 1 Article Nanoparticle targeting of mechanically modulated glycocalyx Kohon Afia Ibnat Man Kun Mathis Katelyn Webb Jade Yang Yong Meckes Brian 27 2 2023 2023.02.27.529887 nihpp-2023.02.27.529887.pdf ABSTRACT The mechanical properties and forces in the extracellular environment surrounding alveolar epithelial cells have the potential to modulate their behavior. Particularly, breathing applies 3-dimensional cyclic stretches to the cells, while the stiffness of the interstitium changes in disease states, such as fibrosis and cancer. A platform was developed that effectively imitates the active forces in the alveolus, while allowing one to control the interstitium matrix stiffnesses to mimic fibrotic lung tumor microenvironments. Alveolar epithelial cancer cells were cultured on these platforms and changes in the glycocalyx expression were evaluated. A complex combination of stiffness and dynamic forces altered heparan sulfate and chondroitin sulfate proteoglycan expressions. Consequently, we designed liposomal nanoparticles (LNPs) modified with peptides that can target heparan sulphate and chondroitin sulfates of cell surface glycocalyx. Cellular uptake of these modified nanoparticles increased in stiffer conditions depending on the stretch state. Namely, chondroitin sulfate A targeting improved uptake efficiency in cells experiencing dynamic stretches, while cells seeded on static stiff interstitium preferentially took up heparan sulfate targeting LNPs. These results demonstrate the critical role that mechanical stiffness and stretching play in the alveolus and the importance of including these properties in nanotherapeutic design for cancer treatment. pmc |
bioRxiv BIORXIV bioRxiv Cold Spring Harbor Laboratory 10.1101/2023.02.26.530139 preprint 1 Article Active maintenance of CD8 + T cell navety through regulation of global genome architecture Russ Brendan E. Tsyganov Kirril Quon Sara Yu Bingfei Li Jasmine Lee Jason K. C. Olshansky Moshe He Zhaohren Harrison Paul F. Barugahare Adele See Michael Nussing Simone Morey Alison E. Udupa Vibha A. Bennett Taylah .J Kallies Axel Murre Cornelis Collas Phillipe Powell David Goldrath Ananda W. Turner Stephen J. 27 2 2023 2023.02.26.530139 nihpp-2023.02.26.530139.pdf SUMMARY The differentiation of nave CD8 + cytotoxic T lymphocytes (CTLs) into effector and memory states results in large scale changes in transcriptional and phenotypic profiles. Little is known about how large-scale changes in genome organisation reflect or underpin these transcriptional programs. We utilised Hi-C to map changes in the spatial organisation of long-range genome contacts within nave, effector and memory virus-specific CD8 + T cells. We observed that the architecture of the naive CD8 + T cell genome was distinct from effector and memory genome configurations with extensive changes within discrete functional chromatin domains. However, deletion of the BACH2 or SATB1 transcription factors was sufficient to remodel the nave chromatin architecture and engage transcriptional programs characteristic of differentiated cells. This suggests that the chromatin architecture within nave CD8 + T cells is preconfigured to undergo autonomous remodelling upon activation, with key transcription factors restraining differentiation by actively enforcing the unique nave chromatin state. One Sentence Summary CD8 + T cell navety is actively maintained by transcription factors that enforce a distinct, nave chromatin architecture. Highlights CD8 + T cell differentiation states are underscored by distinct chromatin looping architectures. Chromatin loops juxtapose CTL state appropriate enhancers, transcription factors and genes. Effector and memory CTLs have similar genome architectures, explaining rapid memory recall. CTL differentiation is restrained by BACH2 and SATB1, which enforce a nave loop architecture. pmc |
bioRxiv BIORXIV bioRxiv Cold Spring Harbor Laboratory 10.1101/2023.02.27.530280 preprint 1 Article A data-fusion approach to identifying developmental dyslexia from multi-omics datasets Carrion Jackson Nandakumar Rohit Shi Xiaojian Gu Haiwei Kim Yookyung Raskind Wendy H. Peter Beate Dinu Valentin 27 2 2023 2023.02.27.530280 nihpp-2023.02.27.530280.pdf Abstract This exploratory study tested and validated the use of data fusion and machine learning techniques to probe high-throughput omics and clinical data with a goal of exploring the etiology of developmental dyslexia. Developmental dyslexia is the leading learning disability in school aged children affecting roughly 5-10% of the US population. The complex biological and neurological phenotype of this life altering disability complicates its diagnosis. Phenome, exome, and metabolome data was collected allowing us to fully explore this system from a behavioral, cellular, and molecular point of view. This study provides a proof of concept showing that data fusion and ensemble learning techniques can outperform traditional machine learning techniques when provided small and complex multi-omics and clinical datasets. Heterogenous stacking classifiers consisting of single-omic experts/models achieved an accuracy of 86%, F1 score of 0.89, and AUC value of 0.83. Ensemble methods also provided a ranked list of important features that suggests exome single nucleotide polymorphisms found in the thalamus and cerebellum could be potential biomarkers for developmental dyslexia and heavily influenced the classification of DD within our machine learning models. pmc |
bioRxiv BIORXIV bioRxiv Cold Spring Harbor Laboratory 10.1101/2023.02.26.530052 preprint 1 Article Interpreting population and family-based genome-wide association studies in the presence of confounding Veller Carl Coop Graham 27 2 2023 2023.02.26.530052 nihpp-2023.02.26.530052.pdf Abstract A central aim of genome-wide association studies (GWASs) is to estimate direct genetic effects: the causal effects on an individual's phenotype of the alleles that they carry. However, estimates of direct effects can be subject to genetic and environmental confounding, and can also absorb the 'indirect' genetic effects of relatives' genotypes. Recently, an important development in controlling for these confounds has been the use of within-family GWASs, which, because of the randomness of Mendelian segregation within pedigrees, are often interpreted as producing unbiased estimates of direct effects. Here, we present a general theoretical analysis of the influence of confounding in standard population-based and within-family GWASs. We show that, contrary to common interpretation, family-based estimates of direct effects can be biased by genetic confounding. In humans, such biases will often be small per-locus, but can be compounded when effect size estimates are used in polygenic scores. We illustrate the influence of genetic confounding on family-based estimates of direct effects using models of assortative mating, population stratification, and stabilizing selection on GWAS traits. We further show how family-based estimates of indirect genetic effects, based on comparisons of parentally transmitted and untransmitted alleles, can suffer substantial genetic confounding. In addition to known biases that can arise in family-based GWASs when interactions between family members are ignored, we show that biases can also arise from gene-by-environment (GxE) interactions when parental genotypes are not distributed identically across interacting environmental and genetic backgrounds. We conclude that, while family-based studies have placed GWAS estimation on a more rigorous footing, they carry subtle issues of interpretation that arise from confounding and interactions. pmc |
bioRxiv BIORXIV bioRxiv Cold Spring Harbor Laboratory 36909522 10.1101/2023.03.01.530608 preprint 2 Article CTLA-4 antibody-drug conjugate reveals autologous destruction of B-lymphocytes associated with regulatory T cell impairment Muthana Musleh M Du Xuexiang Liu Mingyue Wang Xu Wu Wei Ai Chunxia Su Lishan Zheng Pan Liu Yang 29 8 2023 2023.03.01.530608 nihpp-2023.03.01.530608.pdf Germline CTLA-4 deficiency causes severe autoimmune diseases characterized by dysregulation of Foxp3+ Tregs, hyper-activation of effector memory T cells, and variable forms autoimmune cytopenia including gradual loss of B cells. Cancer patients with severe immune-related adverse events (irAE) after receiving anti-CTLA-4/PD-1 combination immunotherapy also have markedly reduced peripheral B cells. The immunological basis for B cell loss remains unexplained. Here we probe the decline of B cells in human CTLA-4 knock-in mice by using anti-human CTLA-4 antibody Ipilimumab conjugated to a drug payload emtansine (Anti-CTLA-4 ADC). The anti-CTLA-4 ADC-treated mice have T cell hyper-proliferation and their differentiation into effector cells which results in B cell depletion. B cell depletion is mediated by both CD4 and CD8 T cells and at least partially rescued by anti-TNF-alpha antibody. These data revealed an unexpected antagonism between T and B cells and the importance of regulatory T cells in preserving B cells. pmc |
Res Sq ResearchSquare Research Square American Journal Experts 10.21203/rs.3.rs-2621222/v1 10.21203/rs.3.rs-2621222 preprint 1 Article Outcome context-dependence is not WEIRD: Comparing description-based economic preferences worldwide Anllo Hernan Bavard Sophie Benmarrakchi FatimaEzzahra Bonagura Darla Cerrotti Fabien Cicue Mirona Gueguen Malle Guzmn Eugenio Kadieva Dzerassa Kobayashi Maiko Lukumon Gafari Sartorio Marco Yang Jiong Zinchenko Oksana Bahrami Bahador Silva Jaime Hertz Uri Konova Anna Li Jian O'Madagain Cathal Navajas Joaquin Reyes Gabriel Sarabi-Jamab Atiye Shestakova Anna Sukumaran Bhasi Watanabe Katsumi Palminteri Stefano 02 3 2023 rs.3.rs-2621222 This work is licensed under a Creative Commons Attribution 4.0 International License, which allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, so long as attribution is given to the creator. The license allows for commercial use. nihpp-rs2621222v1.pdf Abstract Recent evidence indicates that reward value encoding in humans is highly context-dependent, leading to suboptimal decisions in some cases. But whether this computational constraint on valuation is a shared feature of human cognition remains unknown. To address this question, we studied the behavior of individuals from across 11 countries of markedly different socioeconomic and cultural makeup using an experimental approach that reliably captures context effects in reinforcement learning. Our findings show that all samples presented evidence of similar sensitivity to context. Crucially, suboptimal decisions generated by context manipulation were not explained by risk aversion, as estimated through a separate description-based choice task (i.e., lotteries) consisting of matched decision offers. Conversely, risk aversion significantly differed across countries. Overall, our findings suggest that context-dependent reward value encoding is a hardcoded feature of human cognition, while description-based decision-making is significantly sensitive to cultural factors. pmc |
bioRxiv BIORXIV bioRxiv Cold Spring Harbor Laboratory 10.1101/2023.03.01.530592 preprint 1 Article Genome-scale requirements for dynein-based trafficking revealed by a high-content arrayed CRISPR screen Wong Chun Hao Wingett Steven W. Qian Chen Taliaferro J. Matthew Ross-Thriepland Douglas Bullock Simon L. 01 3 2023 2023.03.01.530592 nihpp-2023.03.01.530592.pdf The cytoplasmic dynein-1 (dynein) motor plays a key role in cellular organisation by transporting a wide variety of cellular constituents towards the minus ends of microtubules. However, relatively little is known about how the biosynthesis, assembly and functional diversity of the motor is orchestrated. To address this issue, we have conducted an arrayed CRISPR loss-of-function screen in human cells using the distribution of dynein-tethered peroxisomes and early endosomes as readouts. From a guide RNA library targeting 18,253 genes, 195 validated hits were recovered and parsed into those impacting multiple dynein cargoes and those whose effects are restricted to a subset of cargoes. Clustering of high-dimensional phenotypic fingerprints generated from multiplexed images revealed co-functional genes involved in many cellular processes, including several candidate novel regulators of core dynein functions. Mechanistic analysis of one of these proteins, the RNA-binding protein SUGP1, provides evidence that it promotes cargo trafficking by sustaining functional expression of the dynein activator LIS1. Our dataset represents a rich source of new hypotheses for investigating microtubule-based transport, as well as several other aspects of cellular organisation that were captured by our high-content imaging. pmc |
Res Sq ResearchSquare Research Square American Journal Experts 10.21203/rs.3.rs-2544760/v1 10.21203/rs.3.rs-2544760 preprint 1 Article Mdm2/p53 levels in bone marrow mesenchymal stromal cells is essential for maintaining the hematopoietic niche in response to DNA damage Pourebrahim Rasoul Montoya Rafael Heinz Alaniz Zoe Ostermann Lauren Lin Patrick P. Liu Bin Ayoub Edward Burks Jared K. Andreeff Michael 02 3 2023 rs.3.rs-2544760 This work is licensed under a Creative Commons Attribution 4.0 International License, which allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, so long as attribution is given to the creator. The license allows for commercial use. nihpp-rs2544760v1.pdf Abstract Mesenchymal stromal cells (MSCs) are a key component of the bone marrow (BM) niche, providing essential support required for maintenance of hematopoietic stem cells. To advance our understanding of physiological functions of p53 and Mdm2 in BM-MSCs, we developed traceable conditional mouse models targeting Mdm2 and/or Trp53 in vivo . We demonstrate that Mdm2 is essential for the emergence, maintenance and hematopoietic support of BM-MSCs. Mdm2 haploinsufficiency in BM-MSCs resulted in genotoxic stress-associated thrombocytopenia, suggesting a functional role for Mdm2 in hematopoiesis. In a syngeneic mouse model of acute myeloid leukemia (AML), Trp53 deletion in BM-MSCs improved survival, and protected BM against hematopoietic toxicity from a murine Mdm2i, DS-5272. The transcriptional changes were associated with dysregulation of glycolysis, gluconeogenesis, and Hif-1a in BM-MSCs. Our results reveal a physiologic function of Mdm2 in BM-MSC, identify a previously unknown role of p53 pathway in BM-MSC-mediated support in AML and expand our understanding of the mechanism of hematopoietic toxicity of MDM2is. pmc |
Res Sq ResearchSquare Research Square American Journal Experts 10.21203/rs.3.rs-2622346/v1 10.21203/rs.3.rs-2622346 preprint 1 Article HIV and hepatitis C risk among Tajik migrant workers who inject drugs in Moscow Mackesy-Amiti Mary Ellen Levy Judith A. Bahromov Mahbatsho Jonbekov Jonbek Luc Casey M. 27 2 2023 rs.3.rs-2622346 This work is licensed under a Creative Commons Attribution 4.0 International License, which allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, so long as attribution is given to the creator. The license allows for commercial use. nihpp-rs2622346v1.pdf Abstract Background . The HIV epidemic in Eastern Europe and Central Asia continues to grow with most infections occurring in high-risk groups including people who inject drugs and their sexual partners. Labor migrants from this region who inject drugs while in Russia are at especially high HIV risk. Methods . We recruited 420 male Tajik migrant workers who inject drugs in Moscow for a peer-education HIV prevention intervention trial. Participants were interviewed about their sex and drug use behavior and tested for HIV and hepatitis C prior to the intervention. Results . Over half of the men reported injecting with a previously used syringe in the past month. Many men reported condomless sex (42%), multiple sex partners (30%), and sex with sex workers (42%). Only 17% had ever been tested for HIV. Despite substantial risk behavior, prevalence rates of HIV (6.8%) and HCV (2.9%) although elevated were lower than expected when compared to estimates of prevalence among PWID at the national level in Tajikistan. Risk behavior in diaspora varied across the menaEURTMs regional area of origin in Tajikistan and occupation in Moscow with HIV prevalence rates highest among those working at the bazaars. Conclusion . Tajik male migrants who inject drugs in Moscow are at heightened risk for HIV and hepatitis C. Evidence-based prevention approaches and messaging that specifically address the sex-related risk behavior of migrants from different parts of Tajikistan, employment sectors within the destination city, and socio-demographic background are needed. pmc |
Res Sq ResearchSquare Research Square American Journal Experts 10.21203/rs.3.rs-2622989/v1 10.21203/rs.3.rs-2622989 preprint 1 Article P4HTM: A Novel Downstream Target of GATA3 in Breast Cancer DiDonna Sarah C. Nagornyuk Aerica Adhikari Neeta Takada Mamoru Takaku Motoki 28 2 2023 rs.3.rs-2622989 This work is licensed under a Creative Commons Attribution 4.0 International License, which allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, so long as attribution is given to the creator. The license allows for commercial use. nihpp-rs2622989v1.pdf Abstract Breast cancer continues to be a major cause of death among women. The GATA3 gene is often overexpressed in breast cancer and is widely used to support a diagnosis. However, lower expression of GATA3 has been linked to poorer prognosis along with frequent gene mutations. Therefore, the role of GATA3 in breast cancer appears to be context specific. This study aims to identify a new downstream target of GATA3 to better understand its regulatory network. Clinical data analysis identified the prolyl 4-hydroxylase transmembrane protein (P4HTM) as one of the most highly co-expressed genes with GATA3. Immunohistochemical staining of breast tumors confirms co-expression between GATA3 and P4HTM at the protein level. Similar to GATA3, P4HTM expression levels are linked to patient prognosis, with lower levels indicating poorer survival. Genomics data found that GATA3 binds to the P4HTM locus, and that ectopic expression of GATA3 in basal breast cancer cells increases the P4HTM transcript level. These results collectively suggest that P4HTM is a novel downstream target of GATA3 in breast cancer and is involved in tumor progression. pmc |
Res Sq ResearchSquare Research Square American Journal Experts 10.21203/rs.3.rs-2322768/v1 10.21203/rs.3.rs-2322768 preprint 1 Article An Optrode Array for Spatiotemporally Precise Large-Scale Optogenetic Stimulation of Deep Cortical Layers in Non-human Primates Angelucci Alessandra Clark Andrew Ingold Alexander Reiche Christopher III Donald Cundy Balsor Justin Federer Frederick McAlinden Niall Cheng Yunzhou Rolston John Rieth Loren Dawson Martin Mathieson Keith Blair Steve 28 2 2023 rs.3.rs-2322768 This work is licensed under a Creative Commons Attribution 4.0 International License, which allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, so long as attribution is given to the creator. The license allows for commercial use. nihpp-rs2322768v1.pdf Abstract Optogenetics has transformed studies of neural circuit function, but remains challenging to apply in non-human primates (NHPs). A major challenge is delivering intense and spatially precise patterned photostimulation across large volumes in deep tissue. Here, we have developed and validated the Utah Optrode Array (UOA) to meet this critical need. The UOA is a 1010 glass waveguide array bonded to an electrically-addressable LED array. In vivo electrophysiology and immediate early gene (c-fos) immunohistochemistry demonstrated the UOA allows for large-scale spatiotemporally precise neuromodulation of deep tissue in macaque primary visual cortex. Specifically, the UOA permits both focal (single layers or columns), and large-scale (across multiple layers or columns) photostimulation of deep cortical layers, simply by varying the number of simultaneously activated LEDs and/or the light irradiance. These results establish the UOA as a powerful tool for studying targeted neural populations within single or across multiple deep layers in complex NHP circuits. pmc |
Res Sq ResearchSquare Research Square American Journal Experts 10.21203/rs.3.rs-2517758/v1 10.21203/rs.3.rs-2517758 preprint 1 Article Hydroxymethylation alterations in progenitor-like cell types of pediatric central nervous system tumors are associated with cell type-specific transcriptional changes Lee Min Kyung Azizgolshani Nasim Zhang Ze Perreard Laurent IV Fred Kolling Nguyen Lananh Zanazzi George Salas Lucas Christensen Brock 28 2 2023 rs.3.rs-2517758 This work is licensed under a Creative Commons Attribution 4.0 International License, which allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, so long as attribution is given to the creator. The license allows for commercial use. nihpp-rs2517758v1.pdf Abstract Although intratumoral heterogeneity has been established in pediatric central nervous system tumors, epigenomic alterations at the cell type level have largely remained unresolved. To identify cell type-specific alterations to cytosine modifications in pediatric central nervous system tumors we utilized a multi-omic approach that integrated bulk DNA cytosine modification data (methylation and hydroxymethylation) with both bulk and single-cell RNA-sequencing data. We demonstrate a large reduction in the scope of significantly differentially modified cytosines in tumors when accounting for tumor cell type composition. In the progenitor-like cell types of tumors, we identified a preponderance differential CpG hydroxymethylation rather than methylation. Genes with differential hydroxymethylation, like HDAC4 and IGF1R, were associated with cell type-specific changes in gene expression in tumors. Our results highlight the importance of epigenomic alterations in the progenitor-like cell types and its role in cell type-specific transcriptional regulation in pediatric CNS tumors. pmc |
Food Sci Nutr Food Sci Nutr 10.1002/(ISSN)2048-7177 FSN3 Food Science & Nutrition 2048-7177 John Wiley and Sons Inc. Hoboken 10.1002/fsn3.2737 FSN32737 Original Articles Withdrawal: "Shelf-life extension of buffalo meat using Farsi gum edible coating containing Shirazi thyme essential oil", by Elnaz Saffari Samani, Hossein Jooyandeh, Behrooz Alizadeh Behbahani, Food Science & Nutrition, 2022 18 1 2022 3 2023 11 3 10.1002/fsn3.v11.3 15991599 (c) 2022 The Authors. Food Science & Nutrition published by Wiley Periodicals LLC. This is an open access article under the terms of the License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. source-schema-version-number2.0 cover-dateMarch 2023 details-of-publishers-convertorConverter:WILEY_ML3GV2_TO_JATSPMC version:6.2.6 mode:remove_FC converted:10.03.2023 pmcThe above article, published online on 18 January 2022 in Wiley Online Library ) in Early View, has been withdrawn by agreement between the Journal's Editor-in-Chief, Prof. Y. Martin Lo, and Wiley Periodicals, LLC. The withdrawal has been agreed because the article was published in error while it was still under peer review. The article has now been rejected and is withdrawn. The authors bear no fault, and we apologize for the error. Correction added on 24th November 2022, after initial online publication. A duplicate of this article was published under the DOI:10.1002/fsn3.3087. This duplicate has now been deleted and its DOI redirected to this version of the article. |
s Reviewed Exclusion Criteria Publications Selected for Presentation "Insomnia comorbidities AND depression" date limits set for inclusion from 2011-2021 and limited to clinical trials or randomized control trials 87 Observational study, low participant number, no control group, or involved an insomnia medication without FDA approved indication for treatment for insomnia 5 "Insomnia comorbidities AND anxiety" date limits set for inclusion from 2011-2021 and limited to clinical trials or randomized control trials 53 Observational study, low participant number, no control group, or involved an insomnia medication without FDA approved indication for treatment for insomnia 3 "Insomnia comorbidities AND depression" date limits set for inclusion from 2011-2021 and limited to meta-analysis 23 Observational study, low participant number, no control group, or involved an insomnia medication without FDA approved indication for treatment for insomnia 1 "Insomnia comorbidities AND anxiety" date limits set for inclusion from 2011-2021 and limited to meta-analysis 18 Observational study, low participant number, no control group, or involved an insomnia medication without FDA approved indication for treatment for insomnia 1 Disclaimer/Publisher's Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content. |
DEVELOPMENT AND TREATMENT OF . To the Editors of the Boston Medical Surgical Journal: In view of the notorious inefficacy of our treatment of Bright's disease, I thought the following note might be . It is a condensation of an article read before the French Academie Imp^riale de M^decine, by Prof. Semola of Naples, and is the complement of a previous memoir by the same author. In his previous communication, Prof. Semola developed the opinion that the passage of the albumen into the urine, in Bright's disease, was necessary consequence of a general of nutrition, by which the albumen, rendered incapable of performing its functions, was eliminated by the kidneys as a substance foreign to the organism. According to this theory, the alterations of these organs would play only a secondary role in the development of the disease; and although the of the kidneys is of value in prognosis, Prof. Semola against the ideas of those who pretend to explain or the question by purely anatomical deductions. One diagnostic sign distinguishing organic from symptomatic albuminuria is furnished by the quantity of the urea, which in true Bright's disease diminishes with the first appearance of the albumen, and, at a later period, accumulates in the blood. The same is true of the sulphates. Of the artificial , that produced by the suppression of the cutaneous is the most like Bright's disease. This suppression both prevents the oxidation of the materials introduced into the in the form of peptones (the products of the digestion of , albumen), and causes a congestion of the viscera and especially of the kidneys. Thus, according to this author, Bright's disease is not the result of a primitive anatomical lesion of the kidneys, but is a result of this double series of effects which succeed the more or less sudden suppression of the functions of the skin. The aim of the physician should be to reestablish these , and thus increase the oxidation of the peptones, and the renal congestion. Among the means best suited to this purpose are the sweatings, or, in obstinate cases, hot air baths always by cool or cold shower baths; preparations of arsenic, and inhalations of oxygen. The diet should be vegetable or starchy, with but very little meat. [Boston Med. and Surg. Journal.] W. F, M. |
THE CHICAGO MEDICAL EXAMINER. N. S. DAVIS, M.D., Editor. VOL. IX. FEBRUARY, 1868. NO. 2. (0 n fl i it n I v fl it t n b it 11 fl it si ARTICLE IV. RESULT OF OPERATION FOR HARELIP. By S. D. MERCER, M.D , Omaha, Nebraska. Miss Harriet L., cet. 30, of Omaha, consulted me last March, concerning an operation which she said had been frequently declined, owing to the condition of her general health and the extent of the cleft. For several years she had been troubled with dyspepsia, depending upon inefficient mastication, and from the resulting debility, the lungs had become so irritable that the exhibition of an anaesthetic was very difficult. The above cut represents a deep cleft, of the most unsightly character, rendering the patient an object of disgust to herself and all around her. The chasm extended through the superior maxillary its whole length, the palate bones, and the soft palate, forming a perfect communication between the mouth and left nares. The left side of the nose was very much flattened by contraction of the tissue to the left of the chasm to which the left ala was attached. By the assistance of Drs. Babcock and Canfield, the patient was partially anaesthetized, and, w'ith the bone forceps, the side of both superior maxillaries bordering on the cleft was removed, the edges of the soft parts pared, an incision made from the septum nari to the base of the right ala, and thence about inch toward the external canthus of the right eye, and another from the base of the left ala toward the external of the left eye. Both sides were then freely dissected up, and the margins united with three pins. The wound united, partly by first intention, but some traumatic erysipelas occurred, followed by very slight suppuration, but the union was completed by second intention. The food was subsequently masticated better, and, , the dyspeptic symptoms are gradually disappearing. The patient was referred to the dentist for further improvement. |
Sulphurous Acid in the Treatment of Pyrosis is recommended by Dr. Lawson. In every instance, he asserts, in which it has been employed, it has, in a very short time, arrested the water-brash secretion. It checks the secretion, stops the vomiting, and lessens the epigastric dragging pain so often complained of. Dr. L. considers, , that its good effects are due to the production of ozone and the destruction of vegetable germs. The doses of the acid (B. P.) vary from raxxx to 5j three times a day, shortly before meals. Bitter infusions may be as a vehicle, but plain distilled water is best. The , September, 1868. |
Carter's Bridge, Va., 1868. Apparent Exercise of Volition during Anaestiiesia Complete in all Other Respects. Called, March 3d, 1868, to M , aet. 10 years; female, nervous temperament fully marked; suffering with odontalgia; was very unwilling to allow extraction of the diseased tooth, and closed the jaws so as to successfully resist every effort to part them. At the solicitation of the parents, I subjected her to the influence of chloroform, during the administration of which, she had to be forcibly held upon the couch, so great was her repugnance to extraction, even when assured it would be painless. I my efforts to separate the jaws, while anaesthesia was yet imperfect, but opposing volition was still exercised and baffled the attempts. During this period she opened the mouth and permitted an examination of the tooth, under the assurance that I would not attempt its extraction. When every other evidence of full and complete anaesthesia was present, I still found the jaws so strongly held together as to necessitate leverage in opening the mouth for the admission of the extracting forceps. The resistance was not such as we find in tonic spasm, but to be the result of voluntary effort, arid never yielded, though the anaesthetic was used until the condition of the pupils and pulse forbade its further employment. There was not the least sign of any spasm or rigidity of any other muscles of the system; but, on the contrary, the usual relaxation. W. H. Shepherd, M.D. Richmond and Louisville Medical Journal. |
CORRECTION. Editor of Examiner. In the article on " Tetrachloride of Carbon," of last month, there is an error, implying that Dr. Sherman's experience in giving anoesthetics amounts to " some thousands of cases." It should read "above a thousand of cases." E. ANDREWS, M.D. |
ARTICLE III. CASE OF ADDISON'S OR BRONZED DISEASE. Reported by A. YOUNG, M.D., Prescott, Illinois. As the etiology of this disease is still involved in obscurity, any facts bearing upon it may be of interest to the profession. This iuduces me to give a brief resume of a case which wTas recently under my care. Rev. Mr. R., aged 46, had for several years suffered from ill health, which was, however, not sufficient to interrupt his duties, except by brief intervals. As there was evidence of tubercular deposits in both lungs, his ill health was attributed to this cause. Last winter his general health began to fail; there was some disturbance of the digestive organs, but no apparent increase of the disease of the lungs. About the same time, the skin of the face, neck, and hands, which was naturally rather dark and sallow, began to assume a darker hue, and eventually became as intense as that of a jaundiced person, except that the hue had not the yellow tinge of jaundice, but more nearly resembled a person deeply tanned by exposure. The debility increased, until he was obliged to relinquish his occupation, but was able to be around, complaining of nothing but extreme lassitude and weakness, till September 16th, when persistent nausea and vomiting, with increase of prostration and faintness, supervened, continuing till his death, which occurred September 23d. A post-mortem revealed crude, tubercular deposits in apex of both lungs, some fatty degeneration of heart. Abdominal viscera presenting nothing worthy of note, except kidneys, and supra-renal capsules. Left kidney healthy in structure, with the exception of a small tubercular deposit. Left supra-renal cupsule filled with crude tubercle. The natural texture of the right kidney and supra renal cupsule entirely destroyed, its place being filled by a soft pultaceous mass, undoubtedly softened tubercle. During the time that I knew Mr. R., there was nothing to indicate renal disease, the urine being normal in quantity and quality. |
Civiale's Collection of Calculi. Not long before his death, Civiale exhibited to the French Academy, his collection of urinary calculi, from 2700 patients operated on by him the 43 years of his professional career. In 1600 of the number he had performed his favorite operation of Lithotrity. Pacific Med. $ Surg. Journal. |
MONSTRA ABUNDANTIA. A CASE OF DIFFICULT LABOR FROM DEFORMITY OF TIIE FCETUS. By A. H. De PUY, M.D., Toronto, Ind. Being called to an obstetrical case, a short time ago, in which the diagnosis was very obscure, and the case rendered tedious and protracted in consequence of the deformed state of the child, which proved to be abdominal ascites. It contained about 11 pints of fluid, and measured two feet and one inch in circumference. There was nothing unusual in the first stage of labor, nor until the child's head presented at the inferior strait, when it became apparent that nature was not sufficient to the case. I therefore sent for my obstetrical , and my student, Dr. William H. Burtnett also sent a messenger for Dr. Daniel Camerie; all arrived in due time. The patient being much exhausted, having been in labor 24 hours, we decided to give her an anodyne, and let her rest a short time. After examination and consultation, the pains , we succeeded in bringing down the head and arms, using traction; but making no further progress, we concluded next to dissect the head and shoulders, and perform version. This being done, I succeeded in securing the feet and bringing them down. We then introduced the blunt hook over the pubic bones of the child, using considerable force, but of no avail. Then we determined to remove the bowels and lungs, and thus cause a collapse. But, alas! to our surprise, the moment I perforated the abdominal cavity, an enormous quantity of fluid escaped, and the labor was terminated in a few minutes, vias naturalis. The woman made a good recovery, and is now living in Edgar Co., Ill.; is about 35 years of age, and mother of three children. |
CHAMPAIGN COUNTY MEDICAL SOCIETY. The Fourth Regular Session of the Association was held at the office of Dr. C. II. Mills, in Champaign City, on , April 1st, 1868, and was called to order by the President. The minutes of the last meeting were read and approved. A very interesting paper was read, on the use of the in the treatment of uterine diseases, which was discussed - with spirit and profit. The following officers have been elected for the ensuing year:. President Dr. C. II. Mills. Senior Vice-President H. Somers. Junior " " W. R. Earhart. Treasurer I. T. Pearman. Secretary S. II. Birney. Censors II. C. Howard, I. McHugh, M. S. Brown. Delegates to Illinois State Medical Association Drs. W. Earhart and S. II. Birney. On motion, the Secretary was directed to prepare an account of the proceedings of the Association for publication, and send copies to the Chicago Medical Journal and Examiner. On motion, the Society adjourned, to meet in Urbana the first Wednesday in June. I am happy to state that the Society is in a very flourishing condition. SAM'L II. BIRNEY, Secretary. |
gnmMUgiS of $o entire ALUMNI ASSOCIATION. MINUTES OF THE MEETING OF THE ALUMNI ASSOCIATION OF CHIQAGO MEDICAL COLLEGE, HELD MARCH 3d, 1868. The members of the Alumni Association of Chicago Medical College met in the lower lecture-room of the College, after the commencement exercises. The President, Dr. J. S. Jewell, delivered an able address upon medical education, which was listened to with marked attention, and frequently applauded. On motion, it was the unanimous wish of the alumni that the President be requested to furnish a copy of his address for publication in the Chicago Medical Examiner. Some amendments were then made to the Constitution and By-laws. It was moved, by Dr. Fuller, and carried, that 400 copies of the Constitution and By-laws, as amended, including the 's address, be printed, and a copy sent to each alumnus. Correspondence, and reading and discussion of papers then followed. On motion, the Chairman appointed a Committee, consisting of Drs. John M. Woodworth, J. F. Kelsey, and A. W. Gray, to nominate officers, which Committee, after due conference, presented the following names, which were unanimously elected: President H. P. Merriman, M.D., Chicago. 1st Vice-President N. W. Webber, M.D., Naperville, Ill. 2d Vice-President Norman Bridges, M.D., Chicago. Secy and Treas. S. A. McWilliams, M.D., Chicago. The alumni were then notified that the Treasurer was ready to receive their annual dues. No farther business appearing, the meeting adjourned. s. a. McWilliams, m.d., Sec'y. |
DEATH FROM CHLOROFORM. By B. F. BROWN, M.D., Oneida, Knox Co., Ill. Mrs. Elizabeth Hammon, aged 35, mother of three children, apparently a healthy woman, went to a dentist (Dr. McDowell) April 16, 1868, for the purpose of having some teeth extracted. Thinking she could not endure the pain, she requested the to administer chloroform; and, as he had given it to her once before (about six months since) without any bad effect, he consented to administer it again, and pouring about two drachms of chloroform upon a sponge, held it a short distance from her face. After she had made three or four inspirations her ceased; he felt for the pulse and found she had none. Artificial respiration was commenced at once, and stimulating applications applied over the heart and to the extremities, but to no effect. She made but two or three efforts at inspiration after he first noticed something was wrong. An autopsy could not be obtained. |
u 0 R u 11 f PS a Therapeutics and Materia Medica. A Systematic Treatise on the Action and Uses of Medicinal Agents, Including their Description and History. By Alfred Stille, M.D., Prof. Theory and Practice of Medicine, and of Clinical Medicine, in the University of Pennsylvania; Physician to St. Joseph's Hospital and to the Philadelphia Hospital; etc., etc., etc. Third Edition, Revised and Enlarged. In Two Volumes. Philadelphia: Henry C. Lea. 1868. This, third edition of Dr. Stilld's very complete and valuable work on Therapeutics and Materia Medica, comes to us in two volumes, of over 800 pages each, good type, and good leather binding. The author seems to have carefully revised the wrhole work; and has treated of the following substances, not found in the previous editions, viz.: chromic acid, permanganate , sulphites of soda, etc., carbolic acid, nitrous oxide, , and calabar bean. It is certainly one of the best works on Materia Medica and Therapeutics in our language. For sale by W. B. Keen & Co., 148 Lake Street, Chicago. Odontalgia, commonly called Toothache: Its Causes, , and Cure. By S. Parsons Shaw. Philadelphia: & Co. 1868. This is a neatly published duodecimo volume, of 258 pages. Its title clearly indicates the subjects treated in the work. It is written in pleasing style, and will well repay both physician and dentist for a careful perusal. For sale by S. C. Griggs & Co., Chicago. Archives de Physiologie Normale et Pathologique. Publidrs par MM. Brown-Sequard, Chercot, Vulpian. No. 2 Mers. April, 1868. Avec 5 Planches. Paris: Victor Masson et Fils, Place de L'Ecole de Medicine. This is the title to the second number of a bi-monthly , devoted to physiology and pathology, published in Paris, by Brown-Sdquard, Chercot, and Vulpian. Each number about 200 pages, and is illustrated by plates of the finish. To all who read the French language with facility, this would be an exceedingly interesting and valuable periodical. |
LIQUEFYING LAUGHING GAS. The uniform efficiency and safety of laughing gas as an has prompted The British Medical Journal to suggest that a bottle be made strong enough to hold the gas in a liquid form, and of such weight and dimensions that it may be easily carried by the surgeon in his daily rounds. At present it is used by dentists from large gas-bags, into which it is placed as soon as made. Laughing gas is composed, according to the new , of two atoms of nitrogen and one of oxygen. These two elements are the principal constituents of common air. gas or nitrous oxyde can be liquefied under a pressure of 750 pounds per square inch when at the temperature of 45deg Fahr. The most convenient and safe receptacle for the liquid would be a brass or copper tube, not more than a foot in length, and of such thickness as to resist a pressure of at least 1500 pounds, or several tubes of the ordinary thickness might be united side by side and made entirely safe. To get the nitrous oxyde gas into a portable shape, is "a consummation devoutly to be wished." |
ARTICLE XLII. NEW RECTUM BOUGIE. By J. S. SHERMAN, M.D., Chicago. A bougie is often required which can be passed up the into the sigmoid flexure. The ordinary rectal bougies are too stiff to accommodate themselves to the course of the bowel, while the more flexible double upon themselves before sufficient pressure is used to open the upper sphincter. A bougie should be flexible enough to bend to the hollow of the sacrum and curve of the bowel, and at the same time sufficiently rigid to force its way without coiling. Lead is a substance possessing such properties, and from this metal I have constructed a bougie in the following manner: Have a lead rod drawn out the required length, and a little less than one-third of an inch in diameter. This is introduced into an elastic catheter, or piece of rubber tubing. This is necessary, as lead, from frequent bending, is liable to break; and, if not thus enclosed, there would be danger of losing portions in the rectum. A piece of hard rubber or wood, turned in an oval shape, and attached to the bougie with a rivet, completes the . Various sizes of these may be turned, and used on the same lead rod. For exploring the rectum high up, such an will be found very useful. It may be made hollow, and used for injecting the bowel in cases of intusausception. |
Sao Paulo Med J Sao Paulo Med J spmj Sao Paulo Medical Journal 1516-3180 1806-9460 Associacao Paulista de Medicina - APM 10.1590/1516-3180.2022.0281.R1.300820221erratum Erratum Erratum 30 1 2023 2023 30 1 2023 141 2 177177 This is an open-access article distributed under the terms of the Creative Commons Attribution License pmcIn the manuscript titled "Clinical and laboratory differences between chromosomal and undefined causes of non-obstructive azoospermia: A retrospective study", DOI number 10.1590/1516-3180.2022.0281.R1.30082022, published in the Sao Paulo Medical Journal - Epub ahead of print: Where it read: "Grupo Interdisciplinar de Estudos da Determinacao e Diferenciacao do Sexo (GIEDDS), Hospital das Clinicas da Universidade Estadual de Sao Paulo (UNICAMP), Campinas (SP), Brazil." It should read: "Grupo Interdisciplinar de Estudos da Determinacao e Diferenciacao do Sexo (GIEDDS), Hospital das Clinicas da Universidade Estadual de Campinas (UNICAMP), Campinas (SP), Brazil." |
ion Library GeoTIFF Geographical tag image file format GIS Geographical information system GNU GNU's Not Unix GPS Global positioning system HTTP Hypertext transfer protocol IRUS Intelligent routing using satellite products JSON JavaScript object notation PaaS Platform as a service SNAP SentiNel application platform XML Extensible markup language Figure 1 Workflow of the back-end application. Figure 2 Workflow of the application for day/night menu selection. Figure 3 Workflow of the application for custom menu selection. Figure 4 Workflow of the application for generation of routes and information. Figure 5 SNAP processing graph. Figure 6 Answer times on first request and next requests. Figure 7 Comparison of answer times for multiple products. Figure 8 Time difference between HTTP request and memory. Disclaimer/Publisher's Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content. |
depiction of the layers in the classifier model used in the EDS. Figure 4 Excerpt from the knowledge graph for the medical prevention domain. Figure 5 Excerpt from a knowledge base for diseases (which in this case is diabetes). Figure 6 Rasa story: preventive examinations. Figure 7 Screenshot of dialogue in the medical prevention domain. Figure 8 Example of the virtual coach switching language. Figure 9 The experimental setup. Figure 10 Number of interactions with the devices in the feasibility studies. Figure 11 User responses to the questionnaire following interactions with the Rasa dialogue system. sensors-23-02748-t001_Table 1 Table 1 Classification of sensors. Type/Name Event-Driven Continuous Worn Worn Accelerometer, gyroscope, magnetometer, microphone, etc. Environment Thermometer, barometer, etc. Smart home PIR, opening detector, etc. Camera, electric meter, water meter, etc. Disclaimer/Publisher's Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content. |
Theranostics Theranostics thno Theranostics 1838-7640 Ivyspring International Publisher Sydney 10.7150/thno.82539 thnov13p1419 Erratum Twist1 downregulation of PGC-1a decreases fatty acid oxidation in tubular epithelial cells, leading to kidney fibrosis: Erratum Liu Limin 12* Ning Xiaoxuan 3* Wei Lei 1* Zhou Ying 1 Zhao Lijuan 1 Ma Feng 1 Bai Ming 1 Yang Xiaoxia 1 Wang Di 1 Sun Shiren 1 1 Department of Nephrology, Xijing Hospital, Fourth Military Medical University, No. 127 Chang le West Road, Xi'an, Shaanxi, 710032, China. 2 School of Medicine, Northwest University, 229 Taibai North Road, Xi'an, Shaanxi, 710069, China. 3 Department of Geriatrics, Xijing Hospital, Fourth Military Medical University, No. 127 Chang le West Road, Xi'an, Shaanxi, 710032, China. Corresponding author: Shiren Sun (E-mail: [email protected]). *These authors contributed equally to this work. 2023 22 2 2023 22 2 2023 13 4 14191420 (c) The author(s) 2023 This is an open access article distributed under the terms of the Creative Commons Attribution License ). See for full terms and conditions. pmcThe authors regret that the original version of our paper, unfortunately, contained two incorrect pictures in Figure 2A, where the images for the H&E and Masson staining pictures of the uIRI Sham were incorrect. The correct version of Figure 2A is shown below. The correction made in this erratum does not affect the original data and conclusions. The authors apologize for any inconvenience that the errors may have caused. Figure 2 Corrected figure for original Figure 2A. |
Ecol Evol Ecol Evol 10.1002/(ISSN)2045-7758 ECE3 Ecology and Evolution 2045-7758 John Wiley and Sons Inc. Hoboken 10.1002/ece3.9877 ECE39877 Corrigendum Corrigendum Corrigendum 12 3 2023 3 2023 12 3 2023 13 3 10.1002/ece3.v13.3 e9877 2023 The Authors. Ecology and Evolution published by John Wiley & Sons Ltd. This is an open access article under the terms of the License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. 10.1002/ece3.9833 source-schema-version-number2.0 cover-dateMarch 2023 details-of-publishers-convertorConverter:WILEY_ML3GV2_TO_JATSPMC version:6.2.6 mode:remove_FC converted:12.03.2023 pmcIn the article by Manning and McCoy(2023), the authors would like to correct the Data Availability Statement as shown below: All data are available on Dryad at: The authors apologize for the error. REFERENCE Manning, J. C. , & McCoy, S. J. (2023). Territoriality drives patterns of fixed space use in Caribbean parrotfishes. Ecology and Evolution, 13 , e9833. 10.1002/ece3.9833 36789348 |
] OR "intervention strategy"[Title/Abstract] OR proto-col[Title/Abstract] OR method[Title/Abstract] OR plan[Title/Abstract] OR recommenda-tion[Title/Abstract] OR treatment[Title/Abstract] OR prevention[Title/Abstract])) AND (obese[Title/Abstract] OR obesity[Title/Abstract] OR overweight[Title/Abstract] OR "obesi-ty management"[Title/Abstract])] AND ["physical activity"[Title/Abstract] OR sport[Title/Abstract]]) AND (Child[Title/Abstract] OR childhood[Title/Abstract] OR young[Title/Abstract] OR youth[Title/Abstract] OR "elementary school"[Title/Abstract] OR children[Title/Abstract] OR adolescent[Title/Abstract] OR adolescence[Title/Abstract] OR under 18[Title/Abstract] OR student[Title/Abstract] OR pediatric[Title/Abstract]) AND ([Observational Study[ptyp] OR Multicenter Study[ptyp] OR Clinical Study[ptyp] OR Clinical Trial[ptyp] OR Comparative Study[ptyp] OR Evaluation Studies[ptyp] OR Gov-ernment Publications[ptyp] OR Letter[ptyp] OR Meta-Analysis[ptyp] OR Randomized Controlled Trial[ptyp] OR Validation Studies[ptyp]] AND full text[sb] AND "last 5 years"[PDat] AND Humans[Mesh] AND [English[lang] OR French[lang]] AND [child[MeSH:noexp] OR adolescent[MeSH]]) |
Biol Methods Protoc Biol Methods Protoc biomethods Biology Methods & Protocols 2396-8923 Oxford University Press 10.1093/biomethods/bpad003 bpad003 Correction AcademicSubjects/SCI00960 Correction to: An efficient procedure for the recovery of DNA from formalin-fixed paraffin-embedded tissue sections 2023 13 3 2023 13 3 2023 8 1 bpad003 The Author(s) 2023. Published by Oxford University Press. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. pmcThis is a correction to: Utako Oba, Kenichi Kohashi, Yuhei Sangatsuda, Yoshinao Oda, Koh-Hei Sonoda, Shouichi Ohga, Koji Yoshimoto, Yasuhito Arai, Shinichi Yachida, Tatsuhiro Shibata, Takashi Ito, Fumihito Miura, An efficient procedure for the recovery of DNA from formalin-fixed paraffin-embedded tissue sections, Biology Methods and Protocols, Volume 7, Issue 1, 2022, bpac014, In the originally published version of this manuscript, the final label on the x-axis in Figure 4A was incorrectly given as 8.0E+8, instead of 8.0E+5. In Figure 4D, the labels on the x-axis were incorrectly given as 0.0E+0, 5.0E+8, 10.0E+8, 15.0E+8, instead of 0.0E+0, 0.5E+8, 1.0E+8, and 1.5E+8 These errors have been corrected. |
MMWR Morb Mortal Wkly Rep MMWR Morb Mortal Wkly Rep WR Morbidity and Mortality Weekly Report 0149-2195 1545-861X Centers for Disease Control and Prevention mm7210a6 10.15585/mmwr.mm7210a6 Erratum Erratum: Vol. 72, No. 7 10 3 2023 10 3 2023 10 3 2023 72 10 269269 All material in the MMWR Series is in the public domain and may be used and reprinted without permission; citation as to source, however, is appreciated. Fleming-DutraKE , CieslaAA , RoperLE , Preliminary estimates of effectiveness of monovalent mRNA vaccines in preventing symptomatic SARS-CoV-2 infection among children aged 3-5 years Increasing Community Access to Testing Program, United States, July 2022-February 2023. MMWR Morb Mortal Wkly Rep 2023;72 :177-82. 10.15585/mmwr.mm7207a3 pmcIn the report "Preliminary Estimates of Effectiveness of Monovalent mRNA Vaccines in Preventing Symptomatic SARS-CoV-2 Infection Among Children Aged 3-5 Years Increasing Community Access to Testing Program, United States, July 2022-February 2023," on page 181, the fifth sentence should have read, "By November-December 2022, 87% of U.S. children aged 6 months-4 years had evidence of infection induced SARS-CoV-2 immunityPPPPP; however, caregivers reported previous SARS-CoV-2 infection >3 months earlier for only approximately 20% of children in this analysis, and, therefore, the analysis was not adjusted for previous infection." |
Eur J Ageing Eur J Ageing European Journal of Ageing 1613-9372 1613-9380 Springer Netherlands Dordrecht 36913153 754 10.1007/s10433-023-00754-1 Correction Correction: Social relations and exclusion among people facing death Seppnen Marjaana [email protected] Niemi Mia [email protected] Sarivaara Sofia [email protected] grid.7737.4 0000 0004 0410 2071 University of Helsinki, Helsinki, Finland 13 3 2023 13 3 2023 12 2023 20 1 6 The Author(s) 2023 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit issue-copyright-statement The Author(s) 2023 pmc Correction to: European Journal of Ageing (2023) 20:1 Following publication of the original article , the authors would like to change the corresponding author from Mia Niemi to Marjaana Seppnen. The original article has been corrected. Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. |
, Introduction, and Conclusion. RD and BH wrote Abstract, Introduction, and Conclusion, in addition to substantially editing KA's sections. DH wrote a section of the Introduction. Conflict of interest BH is on the scientific advisory board of Carmine Therapeutics. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Publisher's note All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher. |
PNAS Nexus PNAS Nexus pnasnexus PNAS Nexus 2752-6542 Oxford University Press US 10.1093/pnasnexus/pgad071 pgad071 Correction AcademicSubjects/MED00010 AcademicSubjects/SCI00010 AcademicSubjects/SOC00010 Correction to: Skeletal muscle releases extracellular vesicles with distinct protein and microRNA signatures that function in the muscle microenvironment 3 2023 14 3 2023 14 3 2023 2 3 pgad07114 3 2023 The Author(s) 2023. Published by Oxford University Press on behalf of National Academy of Sciences. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. pmcThis is a correction to: Sho Watanabe, Yuri Sudo, Takumi Makino, Satoshi Kimura, Kenji Tomita, Makoto Noguchi, Hidetoshi Sakurai, Makoto Shimizu, Yu Takahashi, Ryuichiro Sato, Yoshio Yamauchi, Skeletal muscle releases extracellular vesicles with distinct protein and microRNA signatures that function in the muscle microenvironment, PNAS Nexus, Volume 1, Issue 4, September 2022, pgac173, In the originally published version of this manuscript, the image for Calnexin was duplicated in Figure4E's right panel (CD81-isolation) from the left panel. The figure has now been corrected in the article. |
JAMA Netw Open JAMA Netw Open JAMA Network Open 2574-3805 American Medical Association 10.1001/jamanetworkopen.2023.5486 zcx230018 Other Correction Online Only Error in Table 2 Correction 13 3 2023 3 2023 13 3 2023 6 3 e235486Copyright 2023. JAMA Network Open. This is an open access article distributed under the terms of the CC-BY License. jamanetwopen-e235486.pdf pmcIn the Original Investigation titled "Assessment of Quality of Life of Transgender and Gender-Diverse Children and Adolescents in Melbourne, Australia, 2017-2020,"1 published February 2, 2023, in Table 2, the stub column labels under "Suicidality" were transposed. The top label should be "Not present," and the bottom label should be "Present." This article has been corrected.1 Reference 1 Engel L, Majmudar I, Mihalopoulos C, Tollit MA, Pang KC. Assessment of quality of life of transgender and gender-diverse children and adolescents in Melbourne, Australia, 2017-2020. JAMA Netw Open. 2023;6 (2 ):e2254292. doi:10.1001/jamanetworkopen.2022.54292 36729456 |
J Extracell Vesicles J Extracell Vesicles 10.1002/(ISSN)2001-3078 JEV2 Journal of Extracellular Vesicles 2001-3078 John Wiley and Sons Inc. Hoboken 10.1002/jev2.12313 JEV212313 Erratum Erratum Erratum 14 3 2023 3 2023 14 3 2023 12 3 10.1002/jev2.v12.3 12313(c) 2023 The Authors. Journal of Extracellular Vesicles published by Wiley Periodicals, LLC on behalf of the International Society for Extracellular Vesicles. This is an open access article under the terms of the License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. 10.1002/jev2.12278 source-schema-version-number2.0 cover-dateMarch 2023 details-of-publishers-convertorConverter:WILEY_ML3GV2_TO_JATSPMC version:6.2.6 mode:remove_FC converted:14.03.2023 pmcCorrection to "Glioblastoma-derived extracellular vesicle subpopulations following 5-aminolevulinic acid treatment bear diagnostic implications" Hsia, T., Yekula, A., Batool, S. M., Rosenfeld, Y. B., You, D. G., Weissleder, R., Lee, H., Carter, B.S., & Balaj, L. (2022). Glioblastoma-derived extracellular vesicle subpopulations following 5-aminolevulinic acid treatment bear diagnostic implications. Journal of Extracellular Vesicles, 11(11), e12278. The first published version of this paper did not list the below information for co-authors. Hsia and Yekula are co-first authors. We apologize for this error. |
Nanoscale Adv Nanoscale Adv NA NAADAI Nanoscale Advances 2516-0230 RSC d3na90024j 10.1039/d3na90024j Chemistry Correction: Revealing the electronic, optical and photocatalytic properties of PN-M2CO2 (P = Al, Ga; M = Ti, Zr, Hf) heterostructures Munawar M. a Idrees M. a Alrebdi Tahani A. b Amin B. a a Department of Physics, Abbottabad University of Science & Technology Abbottabad 22010 Pakistan [email protected] b Department of Physics, College of Science, Princess Nourah Bint Abdulrahman University P.O. Box 84428 Riyadh 11671 Saudi Arabia [email protected] 6 3 2023 14 3 2023 6 3 2023 5 6 18161816 22 2 2023 22 2 2023 This journal is (c) The Royal Society of Chemistry 2023 RSC Correction for 'Revealing the electronic, optical and photocatalytic properties of PN-M2CO2 (P = Al, Ga; M = Ti, Zr, Hf) heterostructures' by M. Munawar et al., Nanoscale Adv., 2023, Princess Nourah Bint Abdulrahman University 10.13039/501100004242 PNURSP2023R71 pubstatusPaginated Article pmcThe authors regret that the email address of one of the corresponding authors (Tahani A. Alrebdi) was incorrectly listed as [email protected] in the original manuscript. The correct email address ([email protected]) is listed here. The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers. Supplementary Material |
ion form. Abbreviations CAROM COVID-19-Associated misinfoRmation On Messaging apps UNICEF United Nations International Children's Emergency Fund Conflicts of Interest: None declared. |
Medizinrecht Medizinrecht Medizinrecht 0723-8886 1433-8629 Springer Berlin Heidelberg Berlin/Heidelberg 36937331 6419 10.1007/s00350-023-6419-7 Aufstze Das Gesetz zum Schutz von Menschen mit Behinderung in der Triage Grundrechtsschutz in pandemischen Ausnahmesituationen Eufinger Alexander Klemm Victoria grid.449475.f 0000 0001 0669 6924 Wiesbaden Business School, Hochschule RheinMain, Postfach 3251, 65022 Wiesbaden, Deutschland 14 3 2023 14 3 2023 2023 41 3 200204 Der/die Autor(en) 2023 Open Access Dieser Artikel wird unter der Creative Commons Namensnennung 4.0 International Lizenz verffentlicht, welche die Nutzung, Vervielfltigung, Bearbeitung, Verbreitung und Wiedergabe in jeglichem Medium und Format erlaubt, sofern Sie den/die ursprnglichen Autor(en) und die Quelle ordnungsgem nennen, einen Link zur Creative Commons Lizenz beifgen und angeben, ob nderungen vorgenommen wurden. Die in diesem Artikel enthaltenen Bilder und sonstiges Drittmaterial unterliegen ebenfalls der genannten Creative Commons Lizenz, sofern sich aus der Abbildungslegende nichts anderes ergibt. Sofern das betreffende Material nicht unter der genannten Creative Commons Lizenz steht und die betreffende Handlung nicht nach gesetzlichen Vorschriften erlaubt ist, ist fr die oben aufgefhrten Weiterverwendungen des Materials die Einwilligung des jeweiligen Rechteinhabers einzuholen. Weitere Details zur Lizenz entnehmen Sie bitte der Lizenzinformation auf issue-copyright-statement C.H. Beck Verlag oHG, Mnchen und Springer-Verlag GmbH Deutschland, ein Teil von Springer Nature 2023 pmcFunding Open access funding enabled and organized by Projekt DEAL. |
Report of Treasurer, F. S. Davis, M. D. Frank S. Davis, Treasurer, in account with the Society of Homoeopathicians. Dr. To cash received for dues,..........$80.00 " " " interest, .... 1.29 $81.29 Cr. By cash paid for printing,..........$19.25 " on hand,.......................62.04 $81.29 It was moved and carried that the reports of the Secretary and Treasurer be accepted and approved. The Committee on the Seal, Dr. Thurston, Chairman, a design which was accepted by the Society. Dr. Thurston presented an amendment in writing to strike out Sections V and VI of the Declaration of Principles and the last four words of Section IV. Dr. Biegler presented an amendment in writing to substitute "and" for "with" in the second line of Section VII of the By-Laws. Dr. Thomson presented an amendment in writing to change " charges in writing " to " written charges " in Section XIII of By-Laws. |
Neuro Oncol Neuro Oncol neuonc Neuro-Oncology 1522-8517 1523-5866 Oxford University Press US 10.1093/neuonc/noad020 noad020 Corrigenda AcademicSubjects/MED00300 AcademicSubjects/MED00310 Corrigendum to: DDEL-17. TRIPLE INTRAVENTRICULAR CHEMOTHERAPY FOR TREATMENT OF RELAPSED CHOROID PLEXUS CARCINOMA 3 2023 07 2 2023 07 2 2023 25 3 614614 07 2 2023 The Author(s) 2023. Published by Oxford University Press on behalf of the Society for Neuro-Oncology. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. pmcThis is a corrigendum to: Grace Lau, Julie Drummond, Nataliya Zhukova, Paul Wood, Lisa Janson, DDEL-17. TRIPLE INTRAVENTRICULAR CHEMOTHERAPY FOR TREATMENT OF RELAPSED CHOROID PLEXUS CARCINOMA, Neuro-Oncology, Volume 22, Issue Supplement_3, December 2020, Page iii287, In the originally published online version of this manuscript, Paul Wood was inadvertently omitted from the list of authors. This error has now been corrected. |
J Clin Invest J Clin Invest J Clin Invest The Journal of Clinical Investigation 0021-9738 1558-8238 American Society for Clinical Investigation 169986 10.1172/JCI169986 Retraction UCP2-induced fatty acid synthase promotes NLRP3 inflammasome activation during sepsis Moon Jong-Seok Lee Seonmin Park Mi-Ae Siempos Ilias I. Haslip Maria Lee Patty J. Yun Mijin Kim Chun K. Howrylak Judie Ryter Stefan W. Nakahira Kiichi Choi Augustine M.K. 15 3 2023 15 3 2023 15 3 2023 133 6 e169986(c) 2023 Moon et al. 2023 Moon et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit This article is available online at pmcOriginal citation: J Clin Invest. 2015;125(2):665-680. Citation for this retraction: J Clin Invest. 2023;133(6):e169986. Cornell University, Harvard Medical School, and Brigham and Women's Hospital jointly notified the JCI that Figures 3A, 4D, 7B, and 8B and Supplemental Figures 4 and 7A are not reliable. In accordance with the institutional recommendations, the JCI is retracting this article. Version 1 03/15/2023 Electronic publication See the related article at UCP2 promotes inflammation in sepsis through FASN-dependent NLRP3-inflammasome activation. |
J Clin Invest J Clin Invest J Clin Invest The Journal of Clinical Investigation 0021-9738 1558-8238 American Society for Clinical Investigation 170315 10.1172/JCI170315 Retraction CDK4 is an essential insulin effector in adipocytes Lagarrigue Sylviane Lopez-Mejia Isabel C. Denechaud Pierre-Damien Escote Xavier Castillo-Armengol Judit Jimenez Veronica Chavey Carine Giralt Albert Lai Qiuwen Zhang Lianjun Martinez-Carreres Laia Delacuisine Brigitte Annicotte Jean-Sebastien Blanchet Emilie Hure Sebastien Abella Anna Tinahones Francisco J. Vendrell Joan Dubus Pierre Bosch Fatima Kahn C. Ronald Fajas Lluis 15 3 2023 15 3 2023 15 3 2023 133 6 e170315(c) 2023 Lagarrigue et al. 2023 Lagarrigue et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit This article is available online at pmcOriginal citation: J Clin Invest. 2016;126(1):335-348. Citation for this retraction: J Clin Invest. 2023;133(6):170315. At the request of the corresponding author, the JCI is retracting this article. The authors became aware that the genotype of the mice described as Cdk4neo/neo Rip-Cre was incorrect. The correct mouse genotype was Cdk4neo/neo Rip-Cdk4R24C. The model used transgenically expresses the Cdk4R24C allele under the control of the rat insulin promoter (Rip-Cdk4R24C) rather than expressing Cdk4R24C in the Cdk4 locus as described in the article. Due to this unintentional error, the corresponding author requested retraction. Version 1 03/15/2023 Electronic publication See the related article at CDK4 is an essential insulin effector in adipocytes. |
Heliyon Heliyon Heliyon 2405-8440 Elsevier S2405-8440(22)03732-X 10.1016/j.heliyon.2022.e12444 e12444 Erratum Erratum to "Subtitling Arabic profanities into English and that aggro: the case of West Beirut"<[Heliyon 8 (12) (2022) e11953]> Thawabteh Mohammad Ahmad a Al-Adwan Amer [email protected] b* Shqair Amna a a Al-Quds University, Jerusalem, Palestine b Hamad bin Khalifa University, Qatar * Corresponding author. [email protected] 19 12 2022 2 2023 19 12 2022 9 2 e1244412 12 2022 12 12 2022 (c) 2022 The Author(s) 2022 This is an open access article under the CC BY license ). pmcIn the original published version of this article, typesetting errors led to the incorrect appearance of Arabic text in Texts 1 - 10. This has now been corrected. The publisher apologizes for these errors. Both the HTML and PDF versions of the article have been updated to correct the errors. |
Nat Commun Nat Commun Nature Communications 2041-1723 Nature Publishing Group UK London 37218 10.1038/s41467-023-37218-0 Author Correction Author Correction: Untitled public forestlands threaten Amazon conservation Moutinho Paulo [email protected] 1 Azevedo-Ramos Claudia 2 1 Amazon Environmental Research Institute IPAM Amazon, Brasilia, DF Brazil 2 grid.271300.7 0000 0001 2171 5249 Center for Advanced Amazonian Studies NAEA, Federal University of Para, Belem, PA Brazil 14 3 2023 14 3 2023 2023 14 1425(c) The Author(s) 2023 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit Subject terms Conservation biology Environmental impact Politics issue-copyright-statement(c) The Author(s) 2023 pmcCorrection to: Nature Communications 10.1038/s41467-023-36427-x, published online 1 March 2023 The original version of this Article contained an error in the title, which was previously incorrectly given as 'Untitled public forestlands threat Amazon conservation'. The correct version states 'threaten' in place of 'threat'. This has been corrected in both the PDF and HTML versions of the Article. |
Front Oncol Front Oncol Front. Oncol. Frontiers in Oncology 2234-943X Frontiers Media S.A. 10.3389/fonc.2023.1170270 Oncology Erratum Erratum: Re-irradiation of recurrent vertebral metastasis after two previous spinal cord irradiation: A case report Frontiers Production Office * Frontiers Media SA, Lausanne, Switzerland Approved by: Frontiers Editorial Office, Frontiers Media SA, Switzerland *Correspondence: Frontiers Production Office, [email protected] This article was submitted to Radiation Oncology, a section of the journal Frontiers in Oncology 01 3 2023 2023 01 3 2023 13 117027020 2 2023 20 2 2023 Copyright (c) 2023 Frontiers Production Office 2023 Frontiers Production Office This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. An Erratum on Re-irradiation of recurrent vertebral metastasis after two previous spinal cord irradiation: A case report By Bentahila R, Kinj R, Huck C, El Houat Y, Mampuya A, Tuleasca C, Ozsahin M, Bourhis J and Schiappacasse L (2023) Front. Oncol. 12:995376. doi: 10.3389/fonc.2022.995376 retreatment spine stereotactic radiation vertebral metastases radiosurgery pmcAn omission to the funding section of the original article was made in error. The following sentence has been added: "Open access funding was provided by the University of Lausanne". The publisher apologizes for this mistake. The original version of this article has been updated. |
Bangla Supplementary Tables Appendix A Supplementary data related to this article can be found at |
JAMA Netw Open JAMA Netw Open JAMA Network Open 2574-3805 American Medical Association 10.1001/jamanetworkopen.2023.6504 zcx230020 Other Correction Online Only Errors in Figure Titles Correction 14 3 2023 3 2023 14 3 2023 6 3 e236504Copyright 2023. JAMA Network Open. This is an open access article distributed under the terms of the CC-BY License. jamanetwopen-e236504.pdf pmcIn the Original Investigation titled "Incidence Trends of Atopic Dermatitis in Infancy and Early Childhood in a Nationwide Prescription Registry Study in Norway,"1 published November 2, 2018, there were errors in the figure titles. The title of Figure 2 should have been "Interaction of the Incidence Rate (IR) per Person-Year (PY) of Atopic Dermatitis Between Age and Sex," and the title of Figure 3 should have been "Incidence Rate (IR) per Person-Year (PY) in Children with Atopic Dermatitis According to the Indicated Age Group." This article has been corrected.1 Reference 1 Mohn CH, Blix HS, Halvorsen JA, Nafstad P, Valberg M, Lagerlov P. Incidence trends of atopic dermatitis in infancy and early childhood in a nationwide prescription registry study in Norway. JAMA Netw Open. 2018;1 (7 ):e184145. doi:10.1001/jamanetworkopen.2018.4145 30646341 |
J Med Life J Med Life JMedLife Journal of Medicine and Life 1844-122X 1844-3117 Carol Davila University Press Romania JMedLife-16-329 10.25122/jml-2023-1009 Retraction Retraction Notice to: Stem cell and colorectal carcinogenesis Stoian M 1 Stoica V 2 Radulian G 2* 1 Carol Davila University of Medicine and Pharmacy, Bucharest; Internal Medicine Department, Dr. Ion Cantacuzino Clinical Hospital, Bucharest, Romania 2 Carol Davila University of Medicine and Pharmacy, Bucharest, Romania; Nicolae Paulescu National Institute of Diabetes, Nutrition and Metabolic Diseases, Bucharest, Romania * Corresponding Author: Gabriela Radulian, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania; Nicolae Paulescu National Institute of Diabetes, Nutrition and Metabolic Diseases, Bucharest, Romania. E-mail: [email protected] 2 2023 2 2023 16 2 329329 10 2 2023 15 2 2023 (c)2023 JOURNAL of MEDICINE and LIFE 2023 This article is distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted use and redistribution provided that the original author and source are credited. Article J Med Life 2016; 9(1): 6-11; PubMed ID: 27713769 has been retracted at authors' request. pmcRETRACTION The authors hereby retract the article titled Stem cell and colorectal carcinogenesis published in Journal of Medicine and Life, Volume IX, Issue 1, pages 6-11 in 2016 acknowledging significant errors in the literature review and data analysis presented in the article. We apologize to the readers, reviewers, and editors of Journal of Medicine and Life for any inconvenience or concern. 1 Stoian M Stoica V Radulian G Stem cells and colorectal carcinogenesis J Med Life 2016 Jan-Mar 9 1 6 11 27713769 |
Plant Cell Physiol Plant Cell Physiol pcp Plant and Cell Physiology 0032-0781 1471-9053 Oxford University Press UK 10.1093/pcp/pcad010 pcad010 Correction AcademicSubjects/SCI01180 Correction to: Molecular Mechanisms Underlying the Establishment and Maintenance of Vascular Stem Cells in Arabidopsis thaliana 3 2023 02 2 2023 02 2 2023 64 3 363363 25 1 2023 25 1 2023 02 2 2023 The Author(s) 2023. Published by Oxford University Press on behalf of Japanese Society of Plant Physiologists. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. pmcThis is a correction to: Shunji Shimadzu, Tomoyuki Furuya, Yuki Kondo, Molecular Mechanisms Underlying the Establishment and Maintenance of Vascular Stem Cells in Arabidopsis thaliana, Plant and Cell Physiology, 2022, In the original published version of the article, funding information for Open Access publication by KAKENHI grant number 22H04904 was omitted. This information has now been included in the online version, as below: Funding Ministry of Education, Culture, Sports, Science, and Technology of Japan (17H06476 and 22H04720 to Y.K.); Japan Society for the Promotion of Science (20K15815 and 22H02647 to Y.K.); Open Access publication funded by KAKENHI grant number 22H04904. |
ud 0 r r PS s u o n a PS u r PS CASE OF SUPPOSED AMPUTATION OF THE ARM OF FCETUS IN UTERO, FROM MENTAL EMOTION. Wyanet, III., August 15, 1867. Mr. Editor: Mrs. E. H., of this place, was confined on the 11th of October, 1868, by Dr. P. J. Mulvane. The lasted four hours, and it was observed that the left arm of the child had been amputated at the middle third of the humeral region. Upon investigation, it was ascertained that the mother, shortly after becoming pregnant, visited in the East, and while traveling on the cars witnessed the great toe of a child amputated by the car door shutting upon it violently. The mother attributes the cause of the arm amputation, from the sight of the last mentioned. I have seen the child, which is well and hearty, and since it is a case of unusual interest to me, I thought it might be of sufficient interest for publication. J. L. KITCHEN, M.D. |
K D B K iiuiircs Circular No. 2, War Department of Surgeon General's Office. Report on Excisions of the Head of the Femur for Gun Shot Injury. Washington: Government Printing Office. 1869. This is a report of so much of the Surgical History of the late war as relates to Excisions of the Head of the Femur, for Gun Shot Injuries. It is prefaced with a historical review of this operation, and throughout beautifully illustrated. In the qualities of paper, type, and illustration, it certainly does credit to the Department. We have not had time to examine its , but have no doubt of their great value, especially to every practical Surgeon. A Treatise on Diseases of the Eye. By J. Soelberg Wells, Professor of Ophthalmology in King's College, London; Ophthalmic Surgeon to King's College Hospital, and Surgeon to the Royal London Ophthalmic Hospital, Moorfields. First American Edition, with Additions. with 216 engravings on wood, and six colored plates, together with selections from the Test-Types of Prof. E. Jaeger and Dr. H. Sneller. Philadelphia: Henry C. Lea. 1869. This is a full-sized octavo of 736 pages, substantially bound in leather, and on fair type and paper. It is intended to a complete treatise on diseases, injuries, and defects of the organs of vision. This will be found one of the best among many w>rks relating to the same department of medicine and surgery. Report of the Board of Health of New York for the year 1867. This is a full-sized octavo volume, of 635 pages, with many valuable illustrations. To those interested in sanitary science and hygiene it is a volume of special interest. To the ordinary practitioner it furnishes many facts calculated to increase his knowledge of the etiology of diseases, and consequently of the means for their prevention. It contains'a very full and account of the disease called the "Cattle Plague," in all its relations. We presume copies can be obtained by addressing the of the Board, Emmons Clark, New York. |
1'. 0 0 : linturs A Practical Treatise on the Diseases of Women. By 1. Thomas, M.D., Professor of Obstetrics and Diseases of Women and Children, in the College of Physicians and Surgeons, New York; Physician to the Bellvue Hospital; etc., etc., etc. With 225 Illustrations. Second Edition, and improved. Philadelphia: Henry C. Lea. 1869. 627 pages. For sale by S. C. Griggs & Co. It is but a few months since we noticed and commended to our readers the first edition of this work. This edition is in excellent style, and has been carefully revised by the author. It is an excellent practical treatise on the 'diseases of the non-pregnant female. |
ARTICLE XX. THE OXYGEN MIXTURE AS AN ANAESTHETIC. By E. ANDREWS, M.D., Prof, of Principles and Practice of Surgery in Chicago Medical College. Some months since I gave in the Examiner an account of my experiments in the use of a mixture of free oxygen and -gas as an anaesthetic. Special circumstances interrupted for a time my investigations, but the following recent case will serve as an additional example of the action of the mixture: Mrs. W. had a fatty tumor on the back of her neck, which she wished removed at her residence. The mixed gas was carried there in a rubber sac and administered by Dr. Rogers. The inhaler was a silver mouth-piece inserted between the lips, and spreading between the lips and teeth so as to allow of no admixture of atmospheric air. Valves allowed the inspired gas to come from the sac, and the expired air to pass out of an opening into the atmosphere. Thus being , the inhalation commenced. In seventy-five seconds the patient was anaesthetized, presenting a sort of pallor of the lips and slight blueness of the veins, but none of the dark flush and labored breathing produced by unmixed -gas. I proceeded to extirpate the tumor, occupying two minutes in the operation, which I accomplished without any consciousness on the part of the patient. The inhaler was then removed from the mouth, and the patient recovered her senses in about two minutes, waking up pleasantly, without nausea or discomfort. The blood from the incision was a little darker in tint than usual, showing that there was not quite free oxygen enough in the mixture. Chicago, No. 81 Monroe St. |
CARROLL COUNTY MEDICAL SOCIETY. The second regular meeting of this society was held in , on the 23d of February, ultimo. Dr. John L. Hostetter, President elect, presiding. Minutes of previous meeting were read and approved. Dr. N. Stepenson, of Thomson, read a paper on the nature of the action of chloroform as an anaesthetic agent. This was a very able production, and showed that the Doctor has been a very close observer of the action of this article. He advanced some very correct ideas as to its peculiar action in some cases, and gave some very excellent advice as to the mode of administering this agent. Dr. J. Haller, of Lanark, read a paper on the action of sempervirens, but modesty will not allow any upon our own paper. Some of the members having been requested to read papers asked for further time. There was considerable discussion on some of the ideas set forth in the papers read, which passed off very agreeably to all. This is what we want, viz.: free expression of views, and reports of our experience in these matters. By so doing we will be enabled to combat disease more successfully, and make the practice of our noble profession more pleasant. Dr. Hostetter not having a paper prepared on medical ethics offered a verbal report, in a few wTell-timed words, to wit: "Labor diligently and unitedly for the good of suffering ." "In all things whatsoever ye would that men should do to you, do ye even so to them." The following were requested to read papers at our next meeting (and also those who did not read at this meeting are requested to be prepared at our next): On obstetrics, Dr. Jno. L. Hostetter, of Mount Carroll. On the etiology and nature of "shock," Dr. N. Stephenson, of Thomson. On motion of Dr. J. Haller, it was decided to hold the next meeting of this society in Mount Carroll, on the second of June next, at 10 o'clock A.M. We hope to see a good attendance at that time. All members of the press and favorable to a rational system of medicine are invited to meet with us. JNO. L. HOSTETTER, President. J. HALLER, M.D., Secretary. |
ON THE ACTION OF BLOODLETTIING, HEAT, COLD, AND IRRITANTS, IN THE TREATMENT OF DISEASE. By GEORGE JOHNSON, M.D., F.R.C.P., Physician to King's College ; Professor of Medicine in King's College, etc. The general principles which Dr. Johnson has, in this paper, endeavored to establish, are: 1. That the object of bloodletting is to lessen hypertonia of certain parts of the vascular system. 2. Venesection is adapted for lessening engorgements of the venous system, which is usually a result of an impeded through the lungs and left heart. When there are signs of engorgement of the veins and obstruction in the lungs, a feeble arterial pulse does not contraindicate ; and there is no inconsistency in combining the practice of venesection with the administration of stimulants. 3. Local bleeding, by leeches or'by cupping, is useful in many cases of inflammation. The bleeding acts by diverting blood through the superficial arteries from the deeper arteries which supply the inflamed parts. 4. Warm baths, fomentations, poultices, and dry cupping, act in an analogous way to local bleeding, but without actually the blood from the system. 5. Cold contracts the vessels to which it is immediately . The result of this may be a sympathetic contraction of distant and deeper vessels, or a driving in of blood to deeper parts. Cold to the surface, therefore, is an uncertain remedy in cases of internal inflammation. 6. The application of strong irritants, so as to inflame the skin, in the early stage of acute internal inflammations, is a distressing, arid often a mischievous, practice. As a general rule, in cases of inflammation, those local are the most efficacious which are the most painless, and which quicken in the greatest degree the cutaneous circulation. British Medical Journal, Nov. 7. Banking's Abstracts. |
ARTICLE XXIV. EXTRACTION OF A NEEDLE. By C. N. COOPER, M.D. In May, 1868, Gertrude C., aged 2 years, was suddenly seized with violent coughs, choking, and dyspnoea, which lasted several hours, after which she breathed naturally. In following, she complained that something hurt her back. On examination, a foreign substance, apparently a small pin, was discovered just below the inferior angle of the right , pointing externally. It disappeared and reappeared times. April 13th. I was called, with Dr. Clemmer, of this city, to examine the child, and, if practicable, remove the offending substance. We cut down upon the point, seized with forceps, and extracted the pointed end of a needle, about eight lines in length. There was no suppuration before nor after the operation. Is it probable that the needle passed down the larynx and worked its way through the tissues to the surface? Is it more probable that it was thrust into the tissues from without, by the child and its attendants? I should be glad to hear any suggestions on this point. Cresco, Iowa, April 27th, 1869. |
gvurjcjciHgof DeWITT county medical society. The Society met in annual session at the office of Drs. & Edmiston, in the City of Clinton. The President, Dr. J. A. Edmiston, in the chair. Minutes of last meeting read and approved. Dr. W. G. Cochran, of Farmer City, was proposed for and elected. Officers for the ensuing year: President, Dr. John Wright; Vice-President, Dr. J. W. Edmiston; Treasurer, Dr. C. ; Secretary, Dr. Edmiston; Censors, Drs. W. G. , C. Goodbrake, J. IT. Tyler. Dr. Wright, in a neat speech, returned thanks for the honor conferred upon him. The retiring President, Dr. J. A. Edmiston, asked until next regular meeting to complete his annual, address, which was, on motion, granted. Drs. C. Goodbrake and John Wright were elected delegates to the American Medical Association for the next year; and Drs. C. Goodbrake, J. Wright, and B. S. Lewis were elected delegates to the Illinois Medical Society, with power to alternates in case of inability to attend. Various subjects were brought before the meeting and at length. Drs. W. G. Cochran and J. II. Tyler were appointed . On motion, the Secretary was instructed to furnish copies of proceedings to the Clinton papers and Chicago medical journals, for publication. On motion, adjourned until next regular meeting. JOHN A. EDMISTON, Secretary. |
Combination of Chloroform with Opiates for the of Pain. Dr. W. Marshall strongly recommends (G7a<<- goiv Medical Journal. May, 1869) this union of remedies for anodyne purposes. From 10 to 20 minims of chloroform are combined with one or two drachms of compound tincture of camphor (if the pain be moderate), or 10, 20, or 40 minims of Battley's sedative (if it be severe). This generally produces sleep within a few minutes, and its effects are more lasting than those of an opiate alone, and without its disagreeable . It ought to be given in some thickish solution, such as mucilage; otherwise the chloroform will fall to the bottom. The Practitioner. Richmond and Louisville Med. Journal. |
Correction. In my article on "The Bromides,' on page 275 of the Examiner, third line from the bottom, instead of SSss., it should be 5ss. |
CHICAGO COLLEGE OF PHARMACY. Special Meeting New Members Honorary Members Election of Delegates. A special meeting of the Chicago College of Pharmacy was held at their rooms, in Rice's Building, on the afternoon of the 24th June, the President, E. H. Sargent, in the chair. The proceedings of the previous meeting were read and approved. The minutes of the meeting of the Board of Trustees were also read and approved. The following new members were elected James E. Marshall, Centralia, Ill.; George F. Layton, South Bend, Ind.; John C. Evans, New Albany, Ind.; F. M. Goodman, Ph. T. Hines, Edward Vincant, K. A. Hunter, Homer A. Smith, H. T. , Fred C. Webber, George C. Cunningham, Chicago. The following foreign honorary members were, after , elected Dr. J. Attfield, Dr. T. Redwood, Henry Deane, Daniel Hamburg, London, England; H^nry B. Brady, Newcastle-on-Tyne, England; Dr. G. C. Wittsteing, Munich, Bavaria; Dr. H. Hager, Berlin, Prussia; Dr. Frederick Mohr, Bonn, Prussia; Dr. F. A. Fluckiger, Berne, Switzerland; Augustus Ambroise Delandre, Messrs. Robinet and Boullay, Paris; Dr. Arthur Casselmann, St. Petersburg, Russia; Dr. G. Dragendorff, Darpet, Russia. Edward T. Schloctzer was elected a trustee of the college, to fill a vancancy occasioned by the absence from the city of Louis A. Diehl. The following gentlemen were elected as delegates to the College at the Convention of American Pharmaceutical Association, to be held in this city on the 7th of September next Albert E. Ehert, F. Mahla, James W. Mill, George M. Hambright, Thomas Whitfield. The following delegates were appointed to represent the College at the Convention to Revise the National Pharmacopoeia, to be held in Washington in May, 1870 Messrs. Albert E. Ebert, Henry Biroth, C. Louis Diehl. Alternates James W. Mill, F. Mahla, Louis Strehl. The meeting then adjourned. |
Booh dlu tires; A Manual of Elementary Chemistry, Theoretical and Practical, By George Fownes, F.R.S., late Professor of Practical in the University College, London. From the tenth revised and corrected English edition. Edited by Robert Bridges, M.D., Professor of Chemistry in the Philadelphia College of Pharmacy. With 197 Illustrations. : Henry C. Lea. 1869. This a new and carefully revised edition of a well-known text-book of practical chemistry. A number of important additions have been made, and it will continue, as heretofore, to hold the first rank as a text-book for students of medicine. Monograph on Hemorrhagic Malarial Fever. Read to the State Medical Society, and republished from the New Orleans Journal of Medicine. By R. Frazer Michel, M.D., of Montgomery, Alabama. 1869. This is a very interesting monograph of only 19 pages, giving an account of the history, symptoms, pathology, and treatment of a very peculiar and fatal form of malarial fever, as it has prevailed in Alabama, Louisiana, and Texas during the last few years. Carbolic Acid: Its Surgical and Therapeutical Uses. A paper read before the Cincinnati Academy of Medicine, June, 1869. By Wm. B. Davis, M.D., of Cincinnati. This is a paper of 13 printed pages, in which the author gives a very judicious summary of what is known of the actual and therapeutical value of carbolic acid. Treatment of Lachrymal Affections. By Prof. Arlt, Professor of Ophthalmology, at the University of Vienna. Translated by John F. Wightman, M.D. Philadelphia: Lindsay & Blakiston. 1869. This is a monograph of 30 pages, in paper cover, but on type ana paper, it contains, in a oriet compass and cheap form, the present state of our knowledge concerning a very troublesome class of affections. |
r o r o n i has at 0r 1e11 cg MINNESOTA STATE MEDICAL SOCIETY, SEMI- MEETING AT OWATONNA. The State Medical Association convened at Owatonna, at 12 M., on the 16th inst., with Dr. J. H. Murphy temporarily in the Chair. Minutes of last meeting read and approved. A committee of three on Credentials was appointed, when the convention until 2 P.M. AFTERNOON SESSION. Reassembled at the appointed time. Dr. Samuel Willey, President of the Society, arrived and took the Chair. The Committee on Credentials reported the names of 17 physicians as duly qualified for membership, which report was accepted. Dr. H. H. Kimball, the essayist appointed at the previous' annual meeting, being absent, his valuable paper on "" was read by Dr. W. F. Hutchinson. An annimated followed its reading, participated in by a number of gentlemen, upon points presented by the essay. EVENING SESSION. "Quackery," the subject for discussion was, on motion, changed to "Typhoid Fever." After the close of the debate, a resolution was introduced empowering the Chair to appoint a committee of three to report on Typhoid Fever, its origin, cause, and treatment, at the next annual meeting. The gentlemen were appointed as such Committee: Drs. , Richardson, and Mayo. The President, Dr. Willey, offers for competition to members of the Society the two following prizes: $50 for the best essay on Epidemic and Endemic Diseases of Minnesota, and $50 for the best essay on Cerebro-Spinal Meningitis. The respective merits of the essays to be determined by a appointed by the President. A vote of thanks was unanimously adopted to the citizens of Owatonna, and especially Dr. Blood, for the generous extended by them to the members of the Society. The Society then adjourned to the next general meeting at St. Paul, February 2d, 1870. E. J. DAVIS, Secretary. |
ARTICLE XXXII. ' BROMIDE OF AMMONIUM AS AN ANODYNE. By C. N. COOPER, M.D., Cresco, Iowa. Mrs. B., aged 28, gave birth to her first child on the of July 6th, after a tedious labor. Iler attending physician ordered salts to move her bowels. Salts were given, but with no effect. Friday evening, Dr. C., of this place, was called, and requested me to see the case with him. Patient complained of severe pain in epigastrium. Dr. C. gave Dov. pul. freely, with no effect. He then tried morph, and chloroform, but she worse. By his request I injected morph, gr. | into the arm, which quieted her at once, but the relief was only . A free enema gave relief, which it was hoped would be permanent. Oil was administered on the following morning. Opiates were ordered to be given freely if the pain returned. At noon her distress was very great, and the opiates had no effect. I was called at once. She was now not only suffering the pain spoken of, but at nearly every breath there was spasmodic contraction of the diaphragm and abdominal muscles over the epigastrium. I gave morph, gr. |, hr. ammo. gr. viij, and spr. ammo. ar. gtts. xv. In a few minutes she said she felt different, but still some pain. I ordered the same to be continued every half hour till relief, which followed the fourth dose. I visited her in the evening and found her comfortable and happy. July 11th, patient doing well, no pains, except slight discomfort, shifting back and forth between stomach and uterus. She has had no more trouble. I cannot say whether the relief was due to the bromide alone, or its combined action with the morphine. My opinion is that the bromide relived nervous irritation and assisted the morphine in relieving the pain. |
ARTICLE IX. A CASE OF FATTY TUMOR. By GENEROUS L. HENDERSON, M.D., Kokomo, Indiana. Mrs. Rayles, set. 65; small in stature, of a nervous . About 26 years ago, she first noticed a small tumor, the size of a hazelnut, under the right arm, below the axilla, and a little to the anterior. It gradually grew in size, but without any serious pain, until within the past year, when it began to enlarge very rapidly, and ulcerated, with sharp, shooting pains. It was now that it began to undermine her health, and that she was willing to undergo a surgical operation. Gave her tonics and support freely, for a fortnight before the operation; also an anodyne occasionally, to allay the pain and to procure sleep. On the 29th of October, we (Cole and Henderson) called, and found the tumor of an oval shape, somewhat flattened, and well defined; it had a soft, doughy feel. Being assisted by Dr. Shoultz, we determined to operate. First chloroforming her in a supine position, we operated by rapidly making an elliptical incision, and carefully dissecting out all of the tumor, which was readily done, without much hemorrhage: the wound was brought together with pins, plaster, etc. (in fact, we do not use any other suture, it does not absorb moisture, nor produce the irritation that a thread would; and, besides, it holds the parts more firmly in coaptation). The extirpated tumor is seven (7) by eight (8) inches in , and weighs 2 lbs. 2J oz. The wound did not have a tendency to very rapidly heal; but, by gently stimulating it a little with carbolic acid, and giving a good and generous diet, with tonics, it kindly healed, with but little suppuration. She is now well and about her household duties, and a better state of health than she has for years before the operation. |
ARTICLE VIII. A PROPOSITION: RELATING TO THE AND PREVENTION OF CERTAIN ZYMOTIC DISEASES. By THEODORE GRIFFIN, M.D., 789 State Street, Chicago. Those diseases which, after once being developed in the human system, thereby destroy the susceptibility of the system to a second like invasion, may be prevented, or their severity greatly modified, by the introduction into the human system of a like virus, from the lower orders of the animal creation. The diseases which may thus be modified or prevented, to the class known as "Zymotic;" and are small-pox, scarlatina, measles, etc.; including the whole catalogue of alluded to in my proposition. The modification and prevention of once the greatest scourge of mankind small-pox, by the introduction into the human system of a similar virus, taken usually from the cowr, leads fairly to the inference set forth in the foregoing proposition. It has been observed that the cat, horse, and many of the lower animals, are subject to eruptive and other diseases; but I am not aware that careful inquiry has been made into the pathology of these morbid conditions, which, it may be found, have their prototype in the human system. The disease in cows, called cow-pox, is identical with small-pox, and affects alike cows, horses, and monkeys; and human small-pox may be communicated to these animals by the impalpable (the specific effluvia) through the medium of the . May we not discover other of the diseases alluded to, among the lower animals? And if so, may we not hope to obtain similar to those which follow the introduction of the virus into the human system namely, exemption from these diseases? The subject deserves investigation. If we are not able to detect, for example, scarlatina in the cat or dog, we may readily test his susceptibility to the disease by inoculation with the specific poison. Should disease develop itself as a result, we may fairly conclude that we have scarlatina: now we may transfer the virus to the human system, and await the result; which result we may expect to be a modified form of the disease, with complete exemption from a future attack. Let us thus open an avenue through which we may thrust those scourges of our race out of the world, as the immortal Jenner virtually thrust out small-pox, but failed to see the application of the principle upon which it was . |
Case Rep Infect Dis Case Rep Infect Dis CRIID Case Reports in Infectious Diseases 2090-6625 2090-6633 Hindawi 10.1155/2023/9785217 Corrigendum Corrigendum to "Life-Threatening Severe Thrombocytopenia and Mild Autoimmune Hemolytic Anemia Associated with Brucellosis" Ahmed Waleed Amsaib M. [email protected] 1 Khalil Khalid Ahmed 1 Azwari Asma 1 Ebid Gamal T. A. 2 Nazir Imran 1 Aly Mohamed Hassan 1 1Department of Medicine, Security Forces Hospital, Makkah, Saudi Arabia 2Clinical Pathology Consultant, Security Forces Hospital, Makkah, Saudi Arabia 2023 8 3 2023 8 3 2023 2023 97852171 3 2023 1 3 2023 Copyright (c) 2023 Waleed Amsaib M. Ahmed et al. 2023 This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. pmcIn the article titled "Life-Threatening Severe Thrombocytopenia and Mild Autoimmune Hemolytic Anemia Associated with Brucellosis" , some identifiable patient data were unintentionally included. The authors apologize for this error and Figure 1 has been amended to address this. The authors also wish to clarify that written informed consent was obtained from the patient specifically for the publication of this case report. 1 Ahmed W. A. M. Ahmed Khalil K. Azwari A. Ebid G. T. A. Nazir I. Aly M. H. Life-threatening severe thrombocytopenia and mild autoimmune hemolytic anemia associated with brucellosis Case Reports in Infectious Diseases 2023 2023 5 6608279 10.1155/2023/6608279 |
Oncol Lett Oncol Lett OL Oncology Letters 1792-1074 1792-1082 D.A. Spandidos 10.3892/ol.2023.13743 OL-25-4-13743 Retraction [Retracted] Study of miR-143 expression in stomach cancer Huang Shao-Jun Zhu Yu-Fang Liu Zeng Li Qing-Feng Li Zhao-Yuan Fu Wen-Rong 4 2023 06 3 2023 06 3 2023 25 4 157Copyright: (c) Huang et al. 2023 This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited. pmcOncol Lett 16: 4367-4371, 2018; DOI: 10.3892/ol.2018.9173 Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that the flow cytometric data in Fig. 3A on p. 4370, comparing both between and within the 'Control' and 'Overexpression' experimental panels, exhibited unexpected repeating patterns with respect to the distribution of the data. The authors were asked to provide an explanation to account for the potentially anomalous appearance of the data in this figure, although no reply was received from them within the requested time period for a response. The Editor of Oncology Letters has therefore decided that this paper should be retracted from the Journal on the grounds of a lack of confidence in the presented data. The Editor apologizes to the readership for any inconvenience caused. |
Mol Med Rep Mol Med Rep Molecular Medicine Reports 1791-2997 1791-3004 D.A. Spandidos 36866735 10.3892/mmr.2023.12969 MMR-27-4-12969 Retraction [Retracted] Anti-carcinogenic activity of anandamide on human glioma in vitro and in vivo Ma Chao Wu Ting-Ting Jiang Pu-Cha Li Zhi-Qiang Chen Xin-Jun Fu Kai Wang Wei Gong Rui 4 2023 28 2 2023 28 2 2023 27 4 82Copyright: (c) Ma et al. 2023 This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited. pmcMol Med Rep 13: 1558-1662, 2016; DOI: 10.3892/mmr.2015.4721 Following the publication of this paper, it was drawn to the Editors' attention by a concerned reader that certain of the scratch-wound data shown in Fig. 3A were strikingly similar to data appearing in different form in another article by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere prior to its submission to Molecular Medicine Reports, the Editor has decided that this paper should be retracted from the Journal. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused. |
Mol Med Rep Mol Med Rep Molecular Medicine Reports 1791-2997 1791-3004 D.A. Spandidos 36825562 10.3892/mmr.2023.12965 MMR-27-4-12965 Retraction [Retracted] Oxidized-low density lipoprotein accumulates cholesterol esters via the PKCa-adipophilin-ACAT1 pathway in RAW264.7 cells Qiao Yuncheng Guo Dongming Meng Lei Liu Qingnan Liu Xiaohui Tang Chaoke Yi Guanghui Wang Zuo Yin Weidong Tian Guoping Yuan Zhonghua 4 2023 20 2 2023 20 2 2023 27 4 78Copyright: (c) Qiao et al. 2023 This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited. pmcMol Med Rep 12: 3599-3606, 2015; DOI: 10.3892/mmr.2015.3864 Following the publication of the above paper, a concerned reader drew to the Editor's attention that the "con" and "ox-LDL" panels in Fig. 1E on p. 3602, and various data panels included in Figs. 3 and 5 on p. 3604, contained apparent anomalies, including what appeared to be matching patternings of cellular data either within the same figure panels or comparing among the data panels. After having conducted an independent investigation in the Editorial Office, the Editor of Molecular Medicine Reports has determined that the above paper should be retracted from the Journal on account of a lack of confidence in the overall authenticity of the data. After having consulted the authors in this regard, they agreed with the decision to retract this paper. The Editor deeply regrets any inconvenience that has been caused to the readership of the Journal. |
Front Pediatr Front Pediatr Front. Pediatr. Frontiers in Pediatrics 2296-2360 Frontiers Media S.A. 10.3389/fped.2023.1170859 Pediatrics Erratum Erratum: Surgery's role in contemporary osteoarticular infection management Frontiers Production Office* Frontiers Media SA, Lausanne, Switzerland Approved by: Frontiers in Pediatrics, Frontiers Media SA, Switzerland * Correspondence: Frontiers Production Office [email protected] Specialty Section: This article was submitted to Pediatric Infectious Diseases, a section of the journal Frontiers in Pediatrics 02 3 2023 2023 02 3 2023 11 117085921 2 2023 21 2 2023 (c) 2023 Frontiers Production Office. 2023 Frontiers Production Office This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. osteoarticular infection surgery management punction drainage necrotic abscess pmcAn Erratum on Surgery's role in contemporary osteoarticular infection management By De Marco G, Vazquez O, Gavira N, Ramadani A, Steiger C, Dayer R and Ceroni D. (2022) Front. Pediatr. 10:1043251. doi: 10.3389/fped.2022.1043251 An omission to the funding section of the original article was made in error. The following sentence has been added: "Open access funding was provided by the University Of Geneva". The original version of this article has been updated. |
J Appl Clin Med Phys J Appl Clin Med Phys 10.1002/(ISSN)1526-9914 ACM2 Journal of Applied Clinical Medical Physics 1526-9914 John Wiley and Sons Inc. Hoboken 10.1002/acm2.13887 ACM213887 Erratum Errata Erratum: "Academic program recommendations for graduate degrees in medical physics: AAPM Report No. 365 (Revision of Report No. 197)" ERRATUM 16 2 2023 3 2023 16 2 2023 24 3 10.1002/acm2.v24.3 e13887(c) 2023 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, LLC on behalf of The American Association of Physicists in Medicine. This is an open access article under the terms of the License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. 10.1002/acm2.13792 source-schema-version-number2.0 cover-dateMarch 2023 details-of-publishers-convertorConverter:WILEY_ML3GV2_TO_JATSPMC version:6.2.6 mode:remove_FC converted:16.03.2023 pmcThe subsections listed in Sections 3.1.5-3.1.10 and 3.5 were misnumbered. The online version of this article has been corrected accordingly. The typesetters apologize for this error. |
J Appl Clin Med Phys J Appl Clin Med Phys 10.1002/(ISSN)1526-9914 ACM2 Journal of Applied Clinical Medical Physics 1526-9914 John Wiley and Sons Inc. Hoboken 10.1002/acm2.13883 ACM213883 Erratum Errata Erratum: "Effects of variable-width jaw motion on beam characteristics for Radixact Synchrony(r)" 16 2 2023 3 2023 16 2 2023 24 3 10.1002/acm2.v24.3 e13883(c) 2023 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, LLC on behalf of The American Association of Physicists in Medicine. This is an open access article under the terms of the License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. 10.1002/acm2.13234 source-schema-version-number2.0 cover-dateMarch 2023 details-of-publishers-convertorConverter:WILEY_ML3GV2_TO_JATSPMC version:6.2.6 mode:remove_FC converted:16.03.2023 pmcThis erratum corrects the following: Ferris WS, Culberson WS, Smilowitz JB, Bayouth JE. Effects of variable-width jaw motion on beam characteristics for Radixact Synchrony(r). J Appl Clin Med Phys. 2022; 22: 175-181. CONFLICT OF INTEREST John E. Bayouth reports ownership interest in a company that provides consulting services on image-guided radiation therapy technology (MR Guidance, LLC,). He/(his employer) received travel reimbursement/speaking fees from ViewRay Inc. The remaining authors have no conflicts of interest to disclose. |
Front Oncol Front Oncol Front. Oncol. Frontiers in Oncology 2234-943X Frontiers Media S.A. 10.3389/fonc.2023.1170338 Oncology Erratum Erratum: Perfluorocarbon emulsion enhances MR-ARFI displacement and temperature in vitro: Evaluating the response with MRI, NMR, and hydrophone Frontiers Production Office * Frontiers Media SA, Lausanne, Switzerland Approved by: Frontiers Editorial Office, Frontiers Media SA, Switzerland *Correspondence: Frontiers Production Office, [email protected] This article was submitted to Cancer Imaging and Image-directed Interventions, a section of the journal Frontiers in Oncology 02 3 2023 2023 02 3 2023 13 117033820 2 2023 20 2 2023 Copyright (c) 2023 Frontiers Production Office 2023 Frontiers Production Office This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. An Erratum on Perfluorocarbon emulsion enhances MR-ARFI displacement and temperature in vitro: Evaluating the response with MRI, NMR, and hydrophone. By Holman R, Lorton O, Guillemin PC, Desgranges S, Santini F, Preso DB, Farhat M, Contino-Pepin C and Salomir R (2023) Front. Oncol. 12:1025481. doi: 10.3389/fonc.2022.1025481 HIFU hydrophone emulsion sonosensitizers MR-ARFI colloids perfluorocarbons (PFCs) cavitation pmcAn omission to the funding section of the original article was made in error. The following sentence has been added: "Open access funding was provided by the University of Geneva". The original version of this article has been updated. |
Front Physiol Front Physiol Front. Physiol. Frontiers in Physiology 1664-042X Frontiers Media S.A. 1171196 10.3389/fphys.2023.1171196 Physiology Erratum Erratum: Using statistical parametric mapping to assess the association of duty factor and step frequency on running kinetic Frontiers Production Office 10.3389/fphys.2023.1171196 Frontiers Production Office * Frontiers Media SA, Lausanne, Switzerland Approved by: Frontiers Editorial Office, Frontiers Media SA, Switzerland *Correspondence: Frontiers Production Office, [email protected] This article was submitted to Exercise Physiology, a section of the journal Frontiers in Physiology 02 3 2023 2023 02 3 2023 14 117119621 2 2023 21 2 2023 Copyright (c) 2023 . 2023 This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. An Erratum on Using statistical parametric mapping to assess the association of duty factor and step frequency on running kinetic by Patoz A, Lussiana T, Breine B, Piguet E, Gyuriga J, Gindre C and Malatesta D (2022). Front. Physiol. 13:1044363. doi: 10.3389/fphys.2022.1044363 biomechanics running pattern spring-mass model leg stiffness ground reaction force pmcAn omission to the Funding section of the original article was made in error. The following sentence has been added: "Open access funding was provided by the University of Lausanne." The original version of this article has been updated. |
under "Interventions") The primary outcome was length of stay (measured by hospital bed-days) within the year of the study (1 Feb 2020 to 31 Jan 2021) (Methods). The original article has been corrected. The online version of the original article can be found at 10.1186/s12913-022-09011-0. Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. |
A CASE OF DIPHTHERIA. S. Mills Fowler, M. D., Chicago, III. Master K., aged three years. When I first saw this little patient he had been sick for three days, and the parents becoming alarmed, thought it advisable to call in a medical man to share the responsibility of his death. I found him lying on his side with his mouth partly open, with a heavy sort of snoring respiration and a bloody, watery fluid running from his nose, and the characteristic odor of diphtheria in the room. A dirty, grayish white coating covered nearly the whole of the pharynx and fauces, being thickest on the left side. The tonsils and pharynx were much swollen and of a dark purplish red. The neck and throat were swollen on the outside, and very sensitive to touch. Although he seemed in a decided stupor, he did not want anything to come in contact with these parts, and would involuntarily pull at the clothing around the throat. He did not want to be handled or touched; it seemed to cause pain; but preferred to be left quietly on his bed. Lachesis, which was the only remedy that came to my mind, seemed only to palliate; it arrested the progress of the disease,, and that was all. It was tried first in the CM, and later in both higher and lower potencies. The child did not improve, but it got no worse. After two days of this sort of waiting anxiety, and not being able to settle upon any other remedy, I gave one dose of Diph.omm, Swan, dry on the tongue, which acted charmingly, and the little fellow was convalescent in two days. |
CLINICAL CASE. F. G. Davis, M. D., Quincy, III. Mrs. R. L., set. sixty. Thin, tall blonde. May 4th, 1894. Appeared for the removal of a wart on face one inch below the right eye. Wart was horny and hard, the base, which was soft and slightly red. There was some deafness, with neuralgia in head about and sides of face. Unpleasant buzzing in ears. B Caust.lm (F.) dry. May 11th. Wart looks the same, but since taking the remedy has suffered very much with rawness between the toes, smarting and itching; bowels became loose. This foot trouble was an old symptom she had got some better of, but it had begun to come on since the warm weather. B Sac-lac. May 21th. Reports no better ; feet sore; profuse perspiration of feet; used to suffer with herpes on legs. 1^ Kali0TM (F.). June 12th. Reported wart dropped off several days ago, no mark; feet are better. Sac-lac. |
Microbiol Resour Announc Microbiol Resour Announc mra Microbiology Resource Announcements 2576-098X American Society for Microbiology 1752 N St., N.W., Washington, DC 00064-23 10.1128/mra.00064-23 mra.00064-23 Author Correction food-microbiologyFood MicrobiologyCorrection for Ito et al., "Draft Genome Sequence of Lactiplantibacillus pentosus AWA1501, Isolated from Awa-bancha" Ito Fumiya [email protected] Niwa Ryo Syaputri Yolani Ikagawa Yuichiro Mizuno Tomofumi Horie Masanori Iwahashi Hitoshi 27 2 2023 3 2023 27 2 2023 12 3 e00064-23Copyright (c) 2023 Ito et al. 2023 Ito et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license. cover-dateMarch 2023 pmcAUTHOR'S CORRECTION Volume 10, no. 30, e00518-21, 2021, The authors' names were spelled incorrectly in the byline in the original article. The byline should appear as shown in this Author Correction. |
Front Med (Lausanne) Front Med (Lausanne) Front. Med. Frontiers in Medicine 2296-858X Frontiers Media S.A. 10.3389/fmed.2023.1170876 Medicine Erratum Erratum: Effect of COVID-19 vaccination on the menstrual cycle Frontiers Production Office * Frontiers Media SA, Lausanne, Switzerland Approved by: Frontiers Editorial Office, Frontiers Media SA, Switzerland *Correspondence: Frontiers Production Office [email protected] This article was submitted to Obstetrics and Gynecology, a section of the journal Frontiers in Medicine 02 3 2023 2023 02 3 2023 10 117087621 2 2023 21 2 2023 Copyright (c) 2023 Frontiers Production Office. 2023 Frontiers Production Office This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. An Erratum on Effect of COVID-19 vaccination on the menstrual cycle by Chao, M. J., Menon, C., and Elgendi, M. (2022). Front. Med. 9:1065421. doi: 10.3389/fmed.2022.1065421 COVID-19 menstruation menstrual disturbance menstrual change pandemic lockdowns pmcAn omission to the funding section of the original article was made in error. The following sentence has been added: "Open access funding was provided by ETH Zurich." The original article has been updated. |
445), September 10, 2021. The authors would like to thank: our research coordinators Vicki Ephron, RN and Vanessa Thyne, MS; members of the Study DSMB George Declose, MD, Lu-Yu Hwang, MD, and Jonathan Garza, MD; the study Advisory Committee MN, MD, Terry K. Satterwhite, MD, Kathleen Crist, LMSW, MS, Aliya Sarwar, MD, Zhi-Dong Jiang, HD, MD, Valerie Coffman, LVN, and Ashley Alexander, BS, MHCA; the study nurses at UTHealth CRU at Memorial Hermann Hospital, including Carla Wilkerson and Tammy Daniele; and employees at the Kelsey Research Foundation, Dorothy Ruelas, RN and Edina Dervisefendic. Conflict of interest HD and Z-DJ have applied for a patent for the FMT product used in this study. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Publisher's note All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher. |
Eur Heart J Open Eur Heart J Open ehjopen European Heart Journal Open 2752-4191 Oxford University Press US 10.1093/ehjopen/oead023 oead023 Corrigendum AcademicSubjects/MED00200 Corrigendum to: Identifying unmet antithrombotic therapeutic need, and implications for stroke and systemic embolism in atrial fibrillation patients: a population-scale longitudinal study 3 2023 16 3 2023 16 3 2023 3 2 oead023 The Author(s) 2023. Published by Oxford University Press on behalf of the European Society of Cardiology. 2023 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. pmcThis is a corrigendum to: Fatemeh Torabi, Daniel E Harris, Owen Bodger, Ashley Akbari, Ronan A Lyons, Michael Gravenor, Julian P Halcox, Identifying unmet antithrombotic therapeutic need, and implications for stroke and systemic embolism in atrial fibrillation patients: a population-scale longitudinal study, European Heart Journal Open, Volume 2, Issue 6, November 2022, oeac066, In the originally published version of this manuscript, the second exclusion box in Figure2 incorrectly read as follows: 31,696 Excluded: Individuals with a death record prior to baseline of 2012-01-01 under 18 at the baseline This has now been corrected as follows: 4,145,780 Excluded: Individuals who did not meet inclusion criteria of the study |
Disaster Med Public Health Prep Disaster Med Public Health Prep DMP Disaster Medicine and Public Health Preparedness 1935-7893 1938-744X Cambridge University Press New York, USA S1935789323000228 10.1017/dmp.2023.22 Addendum COVID-19: Protecting Health-Care Workers in South Korea - ADDENDUM Jeon Yujeong Kim Yeaeun 2023 03 3 2023 03 3 2023 17 e345(c) The Author(s) 2023 2023 The Author(s) This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence ), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited. DOI: 10.1017/dmp.2021.165, Published by Cambridge University Press 7 June 2021 pmcThe original publication of this article 1 was missing the following acknowledgment: "This article was supported by research funds offered from Catholic University of Pusan in 2020." Reference 1. Jeon, Y. , & Kim, Y. (2022). COVID-19: Protecting Health-Care Workers in South Korea. Disaster Medicine and Public Health Preparedness, 16 (6 ), 2355-2357. Published online June 7, 2021. doi: 10.1017/dmp.2021.165 |
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