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Trends in Cell Biology
|
34_9
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Trends in Cell Biology/34_9.png
|
D
|
Cell biological research is becoming increasingly three dimensional, taking into account
spatial dynamics when studying biological questions. In this special issue of Trends
in Cell Biology, researchers from across various fields discuss how the inner architecture
of the cell, and the external environment that surrounds it, impacts upon cell function.
The cover image, Z-stack projections of a mouse mammary organoid grown in Matrigel
3D cultures, provides a striking example of how considering three-dimensional structure
can offer insight into behaviour. Cover image courtesy of Ian Macara.
|
MAC_Bench/Cell/Story/Trends in Cell Biology/21_1.txt
|
vith
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21_1.txt
|
For 25 years Trends in Cell Biology has kept its readers up to date on the latest research advances by publishing timely,
forward-looking reviews in a concise and accessible manner. In honor of our 25th anniversary, this special issue is devoted to highlighting the ever changing and
expanding field of cell biology. The cover is a mosaic of the cover image from the
inaugural issue of Trends in Cell Biology. The mosaic was created using cover images from the past 25 years. Cover design by
Danielle Loughlin.
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MAC_Bench/Cell/Story/Trends in Cell Biology/26_8.txt
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vitg
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26_8.txt
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In recent years, the bottom-up approach of synthetic biologists has yielded new insight
into fundamental aspects of cell biology. In this special issue, co-guest edited by
Wendell A. Lim and Wallace F. Marshall (editorial on pages 611–612), we highlight
some of the exciting work that has sprung from this intersection between synthetic
and cell biology. On the cover, the construction of a single cell is depicted via
an instruction sheet similar to that which might be found in a child’s game. The cover
is meant to represent the constructionist approach to understanding the inner workings
of the cell. Cover design by Yvonne Blanco.
|
MAC_Bench/Cell/Story/Trends in Cell Biology/22_1.txt
|
clip
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22_1.txt
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Cell-cell interactions are integral to countless biological processes in the
human body, and artificial control of these interactions would enable advances in
basic
research and therapeutic engineering. Researchers have previously overexpressed
endogenous membrane proteins to induce affinity, which tends to have cross-affinity
and trigger unintended signaling. Several engineered methods, from chemical-based
to peptide-based methods, have recently become available to program intercellular
interactions. On pages 277–287 in this issue, Chao et al., the creators of helixCAM,
discuss where the state of the art is for this growing field, along with key areas
of
development. Additionally, they present potential use cases across developmental
biology, immunology, and neuroscience to encourage scientists to experiment with
and incorporate the ability to control cell-cell interactions into constructing their
model systems.Cover design by Kathryn Kamowski.
|
MAC_Bench/Cell/Story/Trends in Cell Biology/34_9.txt
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groundtruth
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34_9.txt
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train
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NATURE REVIEWS GENETICS
|
25_3
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_3.png
|
B
|
COVER: inspired by the Perspective on p447.
Cover design: Patrick Morgan.
|
MAC_Bench/Nature/Story/NATURE REVIEWS GENETICS/23_6.txt
|
vith
|
23_6.txt
|
Inspired by the Review on p698.
Cover design: Patrick Morgan
|
MAC_Bench/Nature/Story/NATURE REVIEWS GENETICS/25_3.txt
|
groundtruth
|
25_3.txt
|
Inspired by the Review on p203
Cover design: Patrick Morgan.
|
MAC_Bench/Nature/Story/NATURE REVIEWS GENETICS/22_9.txt
|
clip
|
22_9.txt
|
Cell-mates' by Patrick Morgan, inspired by the Review on p744.
|
MAC_Bench/Nature/Story/NATURE REVIEWS GENETICS/17_1.txt
|
vitg
|
17_1.txt
|
train
|
Trends in Cancer
|
11_1
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Trends in Cancer/11_1.png
|
D
|
Science benefits from embracing diversity and inclusion. The scientific
community is beginning to bring more attention to this issue, but more work is needed.
As Trends in Cancer celebrates its fifth anniversary, we pledge to amplify the diversity of
voices in our pages – showcasing scientists with diverse gender, geography, ethnicities,
and career-stage perspectives. Cover design by Phillip Krzeminski.
|
MAC_Bench/Cell/Story/Trends in Cancer/6_5.txt
|
vith
|
6_5.txt
|
We invite readers to explore the newest addition to the Trends collection Trends in Cancer, which aims to cover a range of topics in cancer research including the latest developments
in basic, translational and clinical sciences, pharma R&D, technology, ethics, and
policy. The inaugural issue of Trends in Cancer tackles the big questions in cancer research today by leading researchers in the
field. The cover depicts an image of a crab or cancer in Latin. The name cancer comes from early observations by Greek physician Hippocrates
of finger-like projections emanating from the diseased mass, calling to mind the shape
of a crab (carcinos in Greek, and later, cancer in Latin). The concept was developed by Danielle Loughlin and Kip Lyall, and the
image was designed by Kip Lyall.
|
MAC_Bench/Cell/Story/Trends in Cancer/1_4.txt
|
clip
|
1_4.txt
|
Variations in cancer incidence fuel the debate on the relative contributions of intrinsic
vs extrinsic factors. On pages 409–415 in this issue, Thomas et al. add an extra piece to the puzzle by exploring the concept of evolutionary ecology
in oncogenesis, and discuss how an organ ecosystem and its contribution to Darwinian
fitness determines vulnerability to cancer. Cover design by Eric Pélatan.
|
MAC_Bench/Cell/Story/Trends in Cancer/2_5.txt
|
vitg
|
2_5.txt
|
In this issue, Kadali and Shoshani discuss the relationship between
abnormal nuclear structures and the formation of gene amplifications in cancer,
emphasizing their role in tumor heterogeneity and therapy resistance. The cover image
depicts cancer cells breaking chromosome bridges with amplified DNA, generating
ecDNA enclosed within micronuclei. These ecDNA-rich micronuclei, portrayed as
mobile carriers, travel along a winding road symbolizing the dynamic "route to tumor
evolution." Along this path, cancer cells act as builders or laborers, depositing
the
ecDNA-rich micronuclei into the tumor mass, highlighting their contribution to tumor
heterogeneity. Cover image design and illustration by Shilpa Madhavan.
|
MAC_Bench/Cell/Story/Trends in Cancer/11_1.txt
|
groundtruth
|
11_1.txt
|
train
|
Trends in Cognitive Sciences
|
28_3
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/28_3.png
|
D
|
Scientific progress depends on the quality of scientific concepts that reflect researchers'
understanding of their phenomena -- be it the periodic table of elements for chemistry
or the Diagnostic and Statistical Manual for mental disorders. In this issue of Trends in Cognitive Sciences, Marina Dubova & Robert L. Goldstone explore how scientific concepts influence measurement,
experimentation, theorizing, and communication in science, as well as the studied
phenomena themselves. The cover shows a scientist using a triangular mold to decompose
their world, leading to difficulties for the scientist who receives that decomposition
when trying to provide a coherent reconstruction of that world. This exemplifies challenges
for science when trying to develop new, improved scientific concepts by using data
shaped by the original concepts. A third scientist, an allegory for progressive improvement
in scientific concepts, suggests a potentially better, curved mold for breaking down
the world. Cover art by Joe Lee.
|
MAC_Bench/Cell/Story/Trends in Cognitive Sciences/27_6.txt
|
vitg
|
27_6.txt
|
In this issue of Trends in Cognitive Sciences, Núñez critically evaluates the idea that humans have an evolved capacity to represent
number and perform arithmetic. He marshals evidence from non-industrialized nations
and calls for a clearer distinction in the field between quantical and numerical cognition.
Nieder and Núñez exchange letters further debating these ideas. Cover image from iStockphoto/Mike_Kiev.
Cover design by Rebecca Schwarzlose.
|
MAC_Bench/Cell/Story/Trends in Cognitive Sciences/21_7.txt
|
vith
|
21_7.txt
|
In celebration of our 25th anniversary, this issue of Trends in Cognitive Sciences features a series of essays highlighting key open questions that leading scientists
believe the field should explore over the next quarter-century. Reflecting the breadth
of cognitive science, these essays address diverse topics, from episodic memory to
developmental psychology, consciousness to auditory cognition, and the experience
of pain to mind-culture interactions. The real-world applicability of cognitive science,
the interface between cognitive science and artificial intelligence, and the use of
paradigms and methods that capture the dynamics of naturalistic cognition emerge as
key themes. The puzzle pieces on the cover, depicting previous TICS covers, represent the process of knowledge accumulation over the last 25 years. Artwork
by Phillip Krzeminski.
|
MAC_Bench/Cell/Story/Trends in Cognitive Sciences/26_1.txt
|
clip
|
26_1.txt
|
Math anxiety is a significant predictor of math achievement, with a negative
impact comparable to early numerical abilities and socioeconomic status. In this issue
of
Trends in Cognitive Sciences, Lau and colleagues explore the relationship between math
anxiety and math achievement, evaluating key theories such as Reduced Competency
Theory and Processing Efficiency Theory. They propose a novel avoidance theory,
suggesting that math anxiety leads to avoidance behaviors like reduced perseverance
and engagement in math, ultimately affecting math achievement. Cover art from
/Fanatic Studio/Gary Waters/Science Photo Library/Getty Images.
|
MAC_Bench/Cell/Story/Trends in Cognitive Sciences/28_3.txt
|
groundtruth
|
28_3.txt
|
val
|
ACS Applied Engineering Materials
|
2024_10
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_10.png
|
C
|
The ACS AMI Family “2024 Early Career Forum” highlights groundbreaking research and innovative ideas from the emerging authors in the scientific community on a broad range of topics. This edition of the Forum showcases 135 exceptional contributions from early-career scientists worldwide, published across ACS Applied Materials & Interfaces, ACS Applied Bio Materials, ACS Applied Electronic Materials, ACS Applied Engineering Materials, ACS Applied Energy Materials, ACS Applied Nano Materials, ACS Applied Optical Materials, and ACS Applied Polymer Materials.
|
MAC_Bench/ACS/Story/ACS Applied Engineering Materials/2024_1.txt
|
vith
|
2024_1.txt
|
Electrochemical writing hydrogen bubbles on paper: Defect engineered MoS2 particles attached on conductive and porous pyrolyzed paper enables region-specific, tunable, and high-performance hydrogen evolution. View the article.
|
MAC_Bench/ACS/Story/ACS Applied Engineering Materials/2023_11.txt
|
ave_1
|
2023_11.txt
|
Deep eutectic solvent/surfactant functionalized titanium dioxide (TiO2) coated graphene oxide (GO) can be a sensitive, ultrafast (within 3 min), and sustainable adsorbent for the complete removal of hazardous textile dye from industrial effluent.
|
MAC_Bench/ACS/Story/ACS Applied Engineering Materials/2024_10.txt
|
groundtruth
|
2024_10.txt
|
A mesoporous Ag2ZrO3/GO nanocomposite with a high surface area and abundant available active sides was used for photocatalytic environmental remediation. Molecular dynamics endorses the formation of an interphase between Ag2ZrO3 and GO. This dynamic and visually striking cover art captures (Ag2ZrO3/GO nanocomposite) the essence of light as a multifaceted tool for sustainability and scientific progress.
|
MAC_Bench/ACS/Story/ACS Applied Engineering Materials/2024_5.txt
|
clip
|
2024_5.txt
|
train
|
Evidence-Based Dentistry
|
25_2
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Evidence-Based Dentistry/25_2.png
|
D
|
In this issue:
This themed issue of Evidence Based Dentistry explores the evidence underpinning our attempts to help people quit smoking. In particular it examines the role of vaping and its effects on both dental treatment and on the oral cavity.
Cover illustration by Gary Neill
|
MAC_Bench/Nature/Story/Evidence-Based Dentistry/24_1.txt
|
clip
|
24_1.txt
|
In this issue:
This issue of Evidence-Based Dentistry highlights the importance of the two-way relationship between research and practice, and how progress in practice is dependent on evidence provided by research.
Cover illustration by Gary Neill
|
MAC_Bench/Nature/Story/Evidence-Based Dentistry/24_4.txt
|
ave_2
|
24_4.txt
|
In this issue:
This issue of Evidence Based Dentistry seeks to present readers and clinicians with widest possible spectrum of information about dentistry and oral health. It describes evidence from social and public health, oral medicine, and surgical and restorative research. The focus is , however, on the external influences on oral health
Cover illustration by Gary Neill
|
MAC_Bench/Nature/Story/Evidence-Based Dentistry/25_4.txt
|
vitg
|
25_4.txt
|
In this issue:
This issue covers an eclectic mix of evidence which highlights the enormous depth and diversity of knowledge and skill that it takes to be a practising dentist.
Cover illustration by Gary Neill
|
MAC_Bench/Nature/Story/Evidence-Based Dentistry/25_2.txt
|
groundtruth
|
25_2.txt
|
val
|
Trends in Ecology & Evolution
|
39_11
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/39_11.png
|
D
|
On pages 1177–1188, Sally Keith and colleagues introduce the new field of “macrobehaviour”.
This field integrates behavioural ecology and macroecology to provide new insight
into both fields, and has particular relevance for understanding ecological responses
to rapid environmental change. Coral reefs occur throughout the tropics and show clear
geographic patterns in species diversity. As such, reef fish, such as the threespot
damselfish (Dascyllus trimaculatus), pictured here, offer an ideal system in which to study macrobehaviour. Cover credit:
Umeed Mistry.
|
MAC_Bench/Cell/Story/Trends in Ecology & Evolution/38_1.txt
|
clip
|
38_1.txt
|
‘Key innovations’ are phenotypic traits that permit evolutionary shifts into previously
inaccessible ecological spheres. On pages 122–131, Aryeh Miller and colleagues discuss
the history of the term and clarify the relationship between key innovations and adaptive
radiation. They provide an analytic framework to understand the eco-evolutionary dynamics
of many putative key innovations. The cover image shows Graham’s anole (Anolis grahami); the evolution of adhesive toepads in this group of arboreal lizards has provided
evolutionary access to the arboreal zone. Photo credit: Day’s Edge Productions.
|
MAC_Bench/Cell/Story/Trends in Ecology & Evolution/38_12.txt
|
vitg
|
38_12.txt
|
Cancer affects the majority of metazoan species but is rarely considered as an ecosystem
process beyond being a source of mortality. On pp. 628–635 of this issue, Marion Vittecoq,
Frédéric Thomas and colleagues provide a new perspective on the ecological and evolutionary
significance of cancer in wildlife. (Cover image from an original painting by Frédéric
Thomas.)
|
MAC_Bench/Cell/Story/Trends in Ecology & Evolution/28_2.txt
|
vith
|
28_2.txt
|
Organisms can gain information about other individuals through
visual signals. These signals often involve patches of colour that are viewed against
a background that can be another part of the same animal or an environmental
background, both demonstrated by the chromodorid nudibranch depicted here. On
pages 188–198, Eleanor Caves and colleagues argue that how a colour signal is
perceived is highly dependent on its background. As such, to understand the function
and evolution of colour signals, the signal must be considered in conjunction with
the
background as a 'multicomponent' signal. Photo credit: Jordan Casey.
|
MAC_Bench/Cell/Story/Trends in Ecology & Evolution/39_11.txt
|
groundtruth
|
39_11.txt
|
test
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Chemistry of Materials
|
2025_1
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/Chemistry of Materials/2025_1.png
|
B
|
Organometal halide perovskites have emerged as an important new class of materials for photovoltaics. The materials exhibit excellent optoelectronic properties and can be easily formed by solution-based processes. The cover illustrates the self-assembly of low-dimensional structures into bulk materials. This Article explores the phase and processing space for formation of methylammonium lead iodide perovskites. Image designed by Alexander Tokarev (Scientific Illustrations). For more information, see “Impact of Processing Temperature and Composition on the Formation of Methylammonium Lead Iodide Perovskites” by Zhaoning Song, Suneth C. Watthage, Adam B. Phillips, Brandon L. Tompkins, Randy J. Ellingson, and Michael J. Heben* (Chem. Mater. 2015, 27, 4612–4619).
|
MAC_Bench/ACS/Story/Chemistry of Materials/2015_12.txt
|
vith
|
2015_12.txt
|
A new cluster compound of RuSn6In6O16 crystallizes as orange crystals with Ru2+ and Sn2+ in the RuSn6 cluster, while the oxide layer is occupied by In3+. Despite the orange color of the crystals, the compound exhibits blue emission with a significant blue shift from its expected orange fluorescence.
|
MAC_Bench/ACS/Story/Chemistry of Materials/2025_1.txt
|
groundtruth
|
2025_1.txt
|
(Chem. Mater. 2008, 20, 55-60). Cover art by Hyun Joo Lee.
|
MAC_Bench/ACS/Story/Chemistry of Materials/2008_23.txt
|
clip
|
2008_23.txt
|
The drive to produce materials for energy management devices that can withstand large and repeated strains/stresses calls for mechanically lightweight robust electrodes and current collectors. In this Perspective, Vilatela and Marcilla explore the use of fibers of carbon nanotubes as ideal current collectors/active material for light-weight, tough energy management devices. The image on the cover shows an electron micrograph of an array of long, aligned CNTs and a scheme of a supercapacitor with fiber electrodes. For more information, see “Tough Electrodes: Carbon Nanotube Fibers as the Ultimate Current Collectors/Active Material for Energy Management Devices” by Juan J. Vilatela* and Rebeca Marcilla (Chem. Mater. 2015, 27, 6901–6917).
|
MAC_Bench/ACS/Story/Chemistry of Materials/2015_5.txt
|
vitg
|
2015_5.txt
|
train
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Trends in Genetics
|
40_11
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Trends in Genetics/40_11.png
|
C
|
Enhancer regions and promoter regions communicate to control regulated gene expression.
Often these two regions are quite distant from each other on the chromosome. On pages
801–814 in this issue, Zabidi and Stark discuss how enhancers and promoters communicate
with each other via transcription factors and cofactors to control regulated gene
expression. The cover image shows an enhancer region communicating with a promoter.
Smiley face, phone and communication signal images courtesy of istockphoto/tittos.
|
MAC_Bench/Cell/Story/Trends in Genetics/32_1.txt
|
clip
|
32_1.txt
|
This Special Issue of Trends in Genetics covers a range of themes related to organogenesis, from the formation of the central
nervous system to the evolution of the insect eye. The articles in this issue highlight
the commonalities of organ formation that are shared across species and kingdoms,
and provide insight on the mechanisms that underlie organogenesis, including regulation
by non-coding RNA and cell expansion driven by polyploidy. Cover image: iStock/kreatiw.
|
MAC_Bench/Cell/Story/Trends in Genetics/31_7.txt
|
ave_0
|
31_7.txt
|
By virtue of their ability to scan and target partial DNA binding motifs on
nucleosomes in chromatin, pioneer transcription factors can act as master regulators
of
development. On pp. 134–148, Amandine Barral and Ken Zaret describe how pioneer
factors guide cell fate transitions during development. They discuss the structural
and
functional characteristics of pioneer factors that allow them to bind and initiate
opening
of silent chromatin and the consequences for chromatin dynamics and gene expression.
Illustration by Amandine Barral.
|
MAC_Bench/Cell/Story/Trends in Genetics/40_11.txt
|
groundtruth
|
40_11.txt
|
In this special issue of Trends in Genetics, we turn the lens on ourselves. The articles
this month focus on human genetics, with topics ranging from resources and methods
to make the most of the explosion of sequencing data to evolutionary questions about
mutation rates and how selection acts through pregnancy.
|
MAC_Bench/Cell/Story/Trends in Genetics/29_4.txt
|
vitg
|
29_4.txt
|
train
|
Nature Cardiovascular Research
|
3_8
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_8.png
|
C
|
COVID-19 and atherosclerosis
Eberhardt et al. describe how SARS-CoV-2 infects cells within human atherosclerotic lesions, triggering plaque inflammation that contributes to acute cardiovascular complications and long-term risks in patients with COVID-19.
See Eberhardt et al.
Image: Katie Vicari. Cover design: Bethany Vukomanovic
|
MAC_Bench/Nature/Story/Nature Cardiovascular Research/2_3.txt
|
vitg
|
2_3.txt
|
The Lands and Seas of the Planet Heart
Koenig et al. present a comprehensive cellular atlas of healthy and failing human hearts, based on single-cell and single-nucleus RNA sequencing of cardiac biopsies from 45 individuals.
See Koenig et al.
Image: Andrew Koenig. Cover Design: Bethany Vukomanovic
|
MAC_Bench/Nature/Story/Nature Cardiovascular Research/1_10.txt
|
clip
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1_10.txt
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Macrophages improve the function of engineered cardiac microtissue
Hamidzada et al. show that after integration of human embryonic stem cell-derived macrophages into human cardiac microtissue, they adopt the resident fate and improve microtissue function by ingesting stressed cardiomyocytes or their cargo by efferocytosis.
See Hamidzada et al.
Image: Ella Maru Studio. Cover design: Bethany Vukomanovic
|
MAC_Bench/Nature/Story/Nature Cardiovascular Research/3_8.txt
|
groundtruth
|
3_8.txt
|
Explaining heart failure
Fernandez-Patron et al. propose a unifying framework explaining how diverse risk factors such as hypertension, obesity and diabetes lead to the pathogenesis and progression of heart failure.
See Fernandez-Patron et al.
Image: Eugenio Hardy, Center for Molecular Immunology, Cuba and Carlos Fernandez-Patron, University of Alberta, Canada. Cover design: Bethany Vukomanovic
|
MAC_Bench/Nature/Story/Nature Cardiovascular Research/3_7.txt
|
vith
|
3_7.txt
|
train
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Macromolecules
|
2024_17
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/Macromolecules/2024_17.png
|
A
|
Bottlebrush polymers with helical and nonhelical sidechains (tuned by the monomer chirality) impact the backbone breadth in solution and the rate of mechanochemistry. View the article.
|
MAC_Bench/ACS/Story/Macromolecules/2024_17.txt
|
groundtruth
|
2024_17.txt
|
°
|
MAC_Bench/ACS/Story/Macromolecules/2009_8.txt
|
vitg
|
2009_8.txt
|
Over the past 50 years, there has been tremendous progress in the synthesis of macromolecules with complex architectures, mainly by covalent chemistry. The “initiator” for this journey and the springboard for the advent of the other controlled/living polymerizations was the discovery of living anionic polymerization. Nature, the perfect chemist,
|
MAC_Bench/ACS/Story/Macromolecules/2017_21.txt
|
clip
|
2017_21.txt
|
Polyelectrolyte complexation is associative phase separation of oppositely charged polyelectrolytes in aqueous media. See Macromolecules, 2018, 51 (8), pp 2988–2995. View the article.
|
MAC_Bench/ACS/Story/Macromolecules/2018_16.txt
|
vith
|
2018_16.txt
|
test
|
ACS Applied Polymer Materials
|
2024_6
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_6.png
|
C
|
A newly synthesized azobenzene-based monoacrylate molecule (AM) is used to develop multifunctional liquid crystal polymer networks (LCPNs) with photothermal effect. The multifunctionality of the strategically optimized and manufactured AM LCPN was demonstrated through the identification of shape memory, orientation, and self-healing properties.
|
MAC_Bench/ACS/Story/ACS Applied Polymer Materials/2023_11.txt
|
vitg
|
2023_11.txt
|
The cover art depicts a biomimetic 3D-printed armored structure inspired by armadillo shells for durable superhydrophobic surfaces. It showcases hexagonal patterns protecting inner hydrophobic nanoparticles, repelling water droplets. The design illustrates the approach of integrating 3D printing with nanomaterial surface treatments to create wear-resistant, water-repellent coatings for harsh environments.
|
MAC_Bench/ACS/Story/ACS Applied Polymer Materials/2024_3.txt
|
clip
|
2024_3.txt
|
Absorption and photorelease of specific organic substances from aqueous environments using tailored Q-silsesquioxane-azobenzene hybrid sponges. The image was generated through Adobe Photoshop (v 25.12) Generative AI, and the molecular structures were manually created using Avagadro (v 1.2.0).
|
MAC_Bench/ACS/Story/ACS Applied Polymer Materials/2024_6.txt
|
groundtruth
|
2024_6.txt
|
This cover illustration shows superior thermal conducting properties of newly developed liquid crystal (LC) materials derived from improved molecular orientation by polymerization. LC epoxy resins exhibit high thermal conductivity based on mesogen networks oriented by intermolecular interactions with excellent potential as electronic materials.
|
MAC_Bench/ACS/Story/ACS Applied Polymer Materials/2024_4.txt
|
vith
|
2024_4.txt
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train
|
Nature Reviews Clinical Oncology
|
22_2
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/22_2.png
|
A
|
Off-the-shelf cell therapies for patients with cancer, inspired by the Review on p10.
Cover design: Carl Conway
|
MAC_Bench/Nature/Story/Nature Reviews Clinical Oncology/22_2.txt
|
groundtruth
|
22_2.txt
|
Protein degraders enter the clinic, inspired by the Review on p265.
Cover design: Simon Bradbrook
|
MAC_Bench/Nature/Story/Nature Reviews Clinical Oncology/20_9.txt
|
vitg
|
20_9.txt
|
Clonal heterogeneity in multiple myeloma requires effective therapies, a topic discussed in the Review on p71.
Cover design: Simon Bradbrook.
|
MAC_Bench/Nature/Story/Nature Reviews Clinical Oncology/18_11.txt
|
clip
|
18_11.txt
|
Selecting immunotherapy regimens for lung cancer, inspired by the Review on p625.
Cover design: Simon Bradbrook.
|
MAC_Bench/Nature/Story/Nature Reviews Clinical Oncology/18_3.txt
|
vith
|
18_3.txt
|
train
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Lab Animal
|
53_12
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Which of the following options best describe the cover image?
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The PREMISE database of Macaca Fascicularis PET/MRI brain imaging
Nonhuman primate neuroimaging is a rapidly growing and extremely promising area of neuroscience research that suffers from a lack of data. Neuroimaging database sharing can accelerate research in this field, while limiting the number of animals used. A new Article presents The PREMISE database, a PET/MR dataset of Macaca Fascicularis brain images structured according to BIDS standards and available for researchers.
See Becker et al.
Cover image: Marina Spence. Cover design: Marina Spence
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Bringing MRI datasets together
Magnetic resonance imaging (MRI) is a non-invasive imaging modality that can help bridge neuroscience research in nonhuman primates with the humans they are intended to model. But, studies with such animals tend to involve small numbers of subjects, and the task of adapting human equipment and tools to nonhuman primates means labs are often coming up with their own solutions to collecting and analyzing MRI data. Data sharing may help researchers make the most of those animals. With discussions about standards and tool building ongoing, a growing number of labs in the nonhuman primate research community are working to bring their MRI datasets together.
See Neff
Image: Katja Heuer & Roberto Toro. Cover design: Erin Dewalt
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Creating cancer avatars
Depicted on the cover this month are 24 h post-injection zebrafish embryos (72 h post-fertilization) engrafted with PC3 human prostate cancer cells. Zebrafish bearing human cancer cells and fruit flies mirroring the mutation profiles of particular cancer patients may be poised to form ‘avatar armies:’ large numbers of personalized models that could be used to test how an individual’s cancer may progress and respond to treatment.
See Neff
Image: Graham Dellaire, Dalhousie University. Cover design: Erin Dewalt
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50 years of Lab Animal
We’ve gone retro this month to celebrate Lab Animal’s 50th Anniversary! 1971 saw the very first issue of the long-running journal, which has grown to encompass animal research from vivarium to lab bench and everywhere in between and features an ever-growing menagerie of model species. Here’s to 50 more years!
See Editorial
IMAGE: Marina Spence. COVER DESIGN: Marina Spence.
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ACS Central Science
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2025_2
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Which of the following options best describe the cover image?
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C
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Via synergistic photoredox/Brønsted acid catalysis, a novel three-component radical cascade reaction occurred through a radical addition/ring-opening/PCET-promoted radical–radical coupling protocol, affording an array of valuable enantioenriched
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A layer-blocked covalent organic framework (LB-COF) heterogenous film, synthesized via two successive surface-initiated polycondensations, shared superior photocatalytic uranium extraction performance as a result of the formation of a S-scheme heterojunction.
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MAC_Bench/ACS/Story/ACS Central Science/2024_9.txt
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Via synergistic photoredox/Brønsted acid catalysis, a novel three-component radical cascade reaction occurred through a radical addition/ring-opening/PCET-promoted radical–radical coupling protocol, affording an array of valuable enantioenriched
|
MAC_Bench/ACS/Story/ACS Central Science/2025_2.txt
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Shown in cartoon form is the key finding described by Yang et al., namely, that electron transfer between two pyrrole-based macrocycles and iodine can be readily controlled through the judicious choice of small molecule “players” and variations in the concentration. This work advances our understanding of fundamentals relevant to energy, catalysis, and molecular electronics.
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Trends in Immunology
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45_1
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Which of the following options best describe the cover image?
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MAC_Bench/Cell/Cover/Trends in Immunology/45_1.png
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C
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Two articles, by Prinjha and colleagues on pages 29–45 and by Lugli, Youngblood et al. on pages 17–28, provide perspectives on T cell differentiation and memory. The articles
explore the potential of epigenetically and selectively modifying T cell memory and
hybrid states for therapeutic gain. Cover illustration: istock. Cover design by Catarina
Sacristán.
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vith
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Recent large scale studies have highlighted the variability of immune responses in
humans. On pages 637–646, Liston et al. review the nature of these variations and the potential contributing factors. Cover
image adapted from istockphoto, credit elenabs.
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On pages 971–986, Jorfi, Tanzi, and colleagues discuss the role peripheral
immune cells play in contributing to Alzheimer’s disease (AD) pathology, and recent
approaches for studying neuroimmune interactions. The illustration depicts a human
brain where half includes forget-me-not flowers (symbols of AD) that are floating
away.
Therapeutically targeting peripheral immune cells might contribute to ameliorating
AD
and preserving memory. The artist wanted to suggest that the person facing the bright
light looks at a hopeful.
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MAC_Bench/Cell/Story/Trends in Immunology/45_1.txt
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Central to survival is the ability to sense, interpret and respond to stimuli from
the environment, largely the work of the nervous and immune systems. In this Special
Issue, Trends in Immunology explores how these neuroimmune interactions build and maintain system homeostasis,
and influence what happens in disease. Cover image by Avi Friedlich based on a fluorescence
micrograph of immune cells in the meningeal lymphatics of a mouse model of multiple
sclerosis, generously supplied by Jonathan Kipnis and Antoine Louveau. An assembly
of dot-plots generated from the DNA sequence of the CD4 gene was repeatedly rotated
in space, and the resulting image was layered on the micrograph, with adjustments
for size and color. You can see more art by Avi at http://www.behance.net/friedlich.
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Nature Catalysis
|
7_9
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Which of the following options best describe the cover image?
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D
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Two catalysts in synergy
The cover highlights a one-pot process whereby a molecular photocatalyst is used for the generation of C(sp 3) radicals from substrates functionalized as N-hydroxyphthalimide esters and an iron-metalloenzyme performs azidation of such radicals in an enantioselective fashion.
See Rui et al.
Cover design: Alex Whitworth. Image: Xiongyi Huang, Johns Hopkins University, USA
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Artificial biocatalytic systems
Biocatalysis is an enabling technology for a more sustainable future. This Insight provides an overview of engineering enzymes and microbes, as well as methods for interfacing them with abiological materials to improve their performance and range of applications.
The cover comes from an Article by Julia Sanz-Aparicio, Víctor Guallar, Manuel Ferrer and co-workers on engineering enzyme scaffolds with two active sites to synergistically combine biological and new-to-nature chemical transformations.
See Alonso et al.
Image: Julia Sanz-Aparicio (CSIC). Cover Design: Valentina Monaco.
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Active sites revealed
In their work, the authors present a methodology to map the active sites of nanoparticle catalysts via a combination of atomic electron tomography and first-principles-trained machine learning. This allows them to draw structure–activity relationships and propose a local environment descriptor.
See Yang et al.
Image: Yao Yang, Westlake University. Cover design: Alex Whitworth
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Decarboxylating malonyl-CoA
Acetyl-CoA carboxylation is the canonical route for endogenous malonyl-CoA formation in cells. Now, Li et al. report a non-carboxylative malonyl-CoA pathway, independent of acetyl-CoA. This enables the biosynthesis of multiple malonyl-CoA-derived natural products, also in multiple cellular hosts.
See Li et al.
Image: Jian Li, Shanghai Jiao Tong University. Cover design: Alex Whitworth
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MAC_Bench/Nature/Story/Nature Catalysis/7_9.txt
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groundtruth
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Cell Host&Microbe
|
32_5
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Which of the following options best describe the cover image?
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MAC_Bench/Cell/Cover/Cell Host&Microbe/32_5.png
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A
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On the cover: This special issue of Cell Host & Microbe presents a collection of articles highlighting the role of the microbiome in systemic
disease. This collection covers recent scientific advances and perspectives for future
research, including commentaries from Sartor discussing personalized treatment for
microbiome-associated diseases, Blaak and colleagues examining how gas measurements
may be used as a measurement of host health, and Gerber discussing the potential of
AI in microbiome research. Also in this issue, Boleij and colleagues consider the
role of the microbiome in cancer, Fernandez-Real and colleagues reflect on the communication
between gut microbes and the CNS, while Garza and colleagues examine the interactions
between microbiota and skin cells and Nieuwdorp and colleagues review the role of
the gut microbiota in the pathophysiology of diabetes. Further, a series of primary
research articles present new research into the systemic reach of the microbiome in
diseases and responses to therapeutic interventions. The cover image by Shen et al. draws on the Chinese theory of yin-yang harmony in which seven nutrients, including
dietary fiber, coordinate with each other to maintain the balance of the microbiota
in the human gut. A diverse diet works together to maintain health through the gut
microbiome, thereby illustrating an example of systemic coordination between the microbiome
and host behavior in health and disease.
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groundtruth
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32_5.txt
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On the cover: This issue marks the 10th anniversary of Cell Host & Microbe. In celebration, we feature Commentaries from the authors of 10 seminal papers published
in the journal this past decade. In these Commentaries, the authors recount the events
and thinking behind the paper and reflect on the progress since its publication. For
details, see the Editorial by Goyal (pp. 269). Artwork by Yvonne Blanco.
|
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On the cover: In this issue of Cell Host & Microbe, Zhou et al. explore the complex interactions between human microbiomes and their hosts across
different body sites, revealing that microbiome stability and its impact on health
are influenced by site-specific host factors. Their findings underscore the systemic
nature of host-microbiome relationships, with significant implications for understanding
metabolic diseases. Cover design by artist Lettie McGuire.
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MAC_Bench/Cell/Story/Cell Host&Microbe/32_9.txt
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On the cover: Since its identification in December 2019, SARS-CoV-2 has circulated
the globe and continues to adapt to its human host. In response, our immune system
presents an arsenal of defense strategies, which can be bolstered by vaccine (re-)enforcements.
In this Special Issue of Cell Host & Microbe, we present a series of articles that highlight this host-virus interplay, depicted
on the cover as an abstract portrayal of how the host (magenta) and virus (blue) continuously
interact. The innate immune response to SARS-CoV-2 is reviewed by Lowery et al. (1052–1062),
while the adaptive responses are addressed by Röltgen and Boyd (1063–1075) and Grifoni
et al. (1076–1092), with Tauzin et al. (1137–1150) and Motozono et al. (1124–1136)
reporting how a single vaccine dose and key residue changes in emerging variants impact
adaptive immunity, respectively. Wang and colleagues (1043–1047) discuss how overactive
immune responses can have lasting consequences, and Bogunovic and Merad (1040–1042)
comment on SARS-CoV-2 in children; Montefiori and Acharya (1162) provide a SnapShot
of SARS-CoV-2 antibodies of therapeutic interest, and Case et al. (1151–1161) report
on the therapeutic efficacy of miniproteins. Decades of work in HIV have been critical
for our rapid response to SARS-CoV-2, as discussed by Fischer et al. (1093–1110),
who compare these two pandemic viruses. Strategies that enabled the rapid development
and distribution of vaccines along with challenges ahead are reviewed by Subbarao
(1111–1123), while Schaeffer et al. (1048–1051) discuss the prospect of herd immunity
and Bhadelia (1036–1039) highlights the need to curb global inequalities in vaccine
distribution. Cover illustration by Julie Ho Sung.
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Trends in Chemistry
|
6_5
|
Which of the following options best describe the cover image?
|
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|
D
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In this special issue of Trends in Chemistry, we highlight the design and emerging catalytic applications of transition metals
and their complexes in organic and organometallic chemistry, including: C-C bond formation,
C-H functionalization, branch-selective olefin hydroarylation, carbon-dioxide methanation,
and chemo-catalytic cellulose conversion to ethanol. On pages 510–523 of this issue,
Rueping and colleagues discuss visible light-induced excited-state transition-metal
catalysis. In contrast to metal/photoredox dual catalysis which has garnered significant
attention as a bond-forming platform, excited-state transition-metal catalysis employs
a single metal complex as both the photo- and cross-coupling catalyst, offering potential
efficient and economic C-C bond formation.
|
MAC_Bench/Cell/Story/Trends in Chemistry/1_5.txt
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In this special issue of Trends in Chemistry, we wrap up our inaugural content by continuing to address big questions in chemistry.
We introduce 14 new articles outlining key topics in chemistry including: lithium-metal
batteries; electrochemical water splitting; light hydrocarbon separations; glycosidic
bond hydroxylation; and two dimensional materials, just to name a few. The cover image
is a continuation of the Issue 1 cover but now with a collection of molecules, structures
and reactions primarily found within this issue.
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MAC_Bench/Cell/Story/Trends in Chemistry/1_10.txt
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Whilst many often look to past giants to find that spark of inspiration,
there is something exciting in looking to the future. For our two-part fifth anniversary
special issue, Trends in Chemistry is amplifying rising stars and emerging leaders
in
chemistry today. Our cover for Part II continues on from Part I, highlighting some
of the
milestones and many paths taken on the 'great career race' for early-career scientists
today. Each running at their own pace, the authors in this special issue are all aiming
to innovate with an impact, solve real-world problems and become inspiring leaders
themselves. Artwork credit: Phillip Krzeminski
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MAC_Bench/Cell/Story/Trends in Chemistry/6_6.txt
|
vith
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6_6.txt
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Whilst many often look to past giants to find that spark of inspiration,
there is something exciting in looking to the future. For our two-part fifth anniversary
special issue, Trends in Chemistry is amplifying rising stars and emerging leaders
in
chemistry today. Our cover for Part II continues on from Part I, highlighting some
of the
milestones and many paths taken on the 'great career race' for early-career scientists
today. Each running at their own pace, the authors in this special issue are all aiming
to innovate with an impact, solve real-world problems and become inspiring leaders
themselves. Artwork credit: Phillip Krzeminski
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MAC_Bench/Cell/Story/Trends in Chemistry/6_5.txt
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groundtruth
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6_5.txt
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Nature Protocols
|
20_2
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Protocols/20_2.png
|
B
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High spatial resolution imaging of biological tissues using nanospray desorption electrospray ionization mass spectrometry (nano-DESI).
This protocol enables sensitive and quantitative imaging of lipids and metabolites in tissue sections with high throughput and spatial resolution. Hundreds of high-quality ion images were obtained from a single uterine section with a resolution of better than 10 µm.
See Yin et al.
Image: Julia Laskin. Cover Design: Erin Dewalt.
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MAC_Bench/Nature/Story/Nature Protocols/14_1.txt
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vith
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14_1.txt
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Nanoplastics in plant roots
Transmission electron microscopy image (pseudo-color) showing nanoplastics localized near the catheters of Arabidopsis thaliana roots. Nanoplastics appear in white, the cell wall is depicted in green and the cell is highlighted in gold. See Sun et al.
Image: Xian-Zheng Yuan, Shandong University. Cover design: S. Harris
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groundtruth
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20_2.txt
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Human neurons in culture
Image of human striatal organoids that are derived from pluripotent stem cells in vitro and can be integrated with cortical cells to form cortico-striatal assembloids.
See Miura et al.
Image: Sergiu P. Pașca, Stanford University. Cover design: Tulsi Voralia.
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Nervous heart.
The cover shows 3D FLASH immunofluorescence staining of nerves (tyrosine hydroxylase) and extracellular matrix (collagen IV) of a whole murine heart.
See Messal et al.
Image: Axel Behrens. Cover design: Tulsi Voralia.
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Nature Human Behaviour
|
8_8
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Human Behaviour/8_8.png
|
A
|
Chimpanzee social learning
Is know-how copying a uniquely human capacity? Van Leeuwen and colleagues demonstrate that chimpanzees use social learning to acquire a skill that they failed to innovate, which suggests that chimpanzees — like humans — use know-how copying to expand their skill set.
See Van Leeuwen et al.
Image: Chimfunshi Wildlife Orphanage and Clara Dubois. Cover design: Bethany Vukomanovic
|
MAC_Bench/Nature/Story/Nature Human Behaviour/8_8.txt
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groundtruth
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Chimpanzee complex culture
Complex culture isn’t uniquely human. By sampling 39 chimpanzee populations across the African continent, Boesch et al. find that chimpanzees possess a highly diverse culture of termite fishing that differs strongly among groups. Individuals copy group-specific techniques and their combinations with high conformity to maintain a unique group culture.
See Boesch et al.
See also News & Views by Koops
Cover image: Minden Pictures / Alamy Stock Photo. Cover design: Bethany Vukomanovic.
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Nature Human Behaviour turns five
This month, we are celebrating our fifth anniversary with two dedicated Features. In one Feature, we asked 22 leading scientists in some of the key disciplines we cover to share their vision of the future of research in their disciplines. In a second Feature, past and present editors of the journal highlight some of their favourite papers and what made them special.
See Editorial, See also Box-Steffensmeier et al. and See also Antusch et al.
Cover image: incamerastock / Alamy Stock Photo. Cover design: Bethany Vukomanovic.
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Human behaviour and COVID-19
Human behaviour shapes the trajectory of pandemics, and behaviour is crucial to curb and contain disease spread. In this Focus, we bring together expert views from a broad range of disciplines across the behavioural and social sciences, to examine how individual and collective behaviour drive and can mitigate the COVID-19 pandemic.
Cover image: GeorgePeters/DigitalVision Vectors/Getty. Cover design: Bethany Vukomanovic
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Chemistry of Materials
|
2025_4
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/Chemistry of Materials/2025_4.png
|
D
|
oxychalcogenide (Cu2S2)(Sr3Sc2O5), a promising p
|
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anion that perplexed the chemistry community for more than a hundred years. By combining high-pressure/high-temperature synthesis with comprehensive characterization methods guided by first-principles theory, cesium pentazolate salt containing N5
|
MAC_Bench/ACS/Story/Chemistry of Materials/2017_23.txt
|
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2017_23.txt
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,
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The cover art visually captures the fusion of nanomaterials with mitochondria targeting, imaging, and image-guided treatment. The mitochondria are targeted by floating molecules, such as rhodamine and
|
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Neuron
|
113_1
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Neuron/113_1.png
|
C
|
On the cover: A depiction of interneurons as gears in a watch movement—brass wheels
representing their dendrites, and nickel their axons. On the left is a bistratified
cell, and in the center is an O-LM cell. The bridge running left to right represents
stratum pyramidale. A pyramidal neuron takes the role of pallet lever (brass, top
right), receiving oscillatory input from the impulse pin to its apical tuft. Instead
of a balance wheel, this oscillatory input comes from the movement of the interneuron
gears. The output of the pyramidal neuron is the accurate timing of the movement of
the pallet wheel (nickel, bottom right corner), representing the cell’s axon. In this
issue, Katona et al. (pages 872–886) describe the temporal specialization of distinct
hippocampal GABAergic interneurons (in the neuronal machine).
|
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On the cover: In this special issue of Neuron, we present a collection of reviews and perspectives on the neurobiology of aging.
The causes of brain aging are multidimensional and complex. Highlighting this, the
cover image is provided by Schwartz and colleagues, who discuss the impact of the immune system on brain aging and propose the provocative
idea of anti-aging immune therapy.
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On the cover: In this special issue of Neuron, we present a collection of reviews and perspectives on the neurobiology of aging.
The causes of brain aging are multidimensional and complex. Highlighting this, the
cover image is provided by Schwartz and colleagues, who discuss the impact of the immune system on brain aging and propose the provocative
idea of anti-aging immune therapy.
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On the cover: In this issue of Neuron, Safaiyan et al. (pages 1100–1117) identify white-matter-associated microglia (WAMs),
which form in a TREM2-dependent but APOE-independent manner in aging white matter,
where they form nodules that are engaged in phagocytosing damaged myelin. Inside WAMs,
these damaged myelin visualized as membranous whorls. Istanbul-based artist Garip
Ay created the image using a paper marbling technique—or more specifically, the Turkish
method called “ebru” recreated these membranous whorls on water.
|
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Cancer Cell
|
42_3
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Which of the following options best describe the cover image?
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MAC_Bench/Cell/Cover/Cancer Cell/42_3.png
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C
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On the cover: By applying spatial epitope barcoding, Rovira-Clave et al. (pp. 1423–1439)
dissected the spatial composition of cancer cell clones, their phenotypes, and their
cell states in xenografts of small-cell lung cancer. The pebbles represent the different
clonal cancer cells and their patches arising in the tumor. The image was generated
using Stable Diffusion, a latent text-to-image diffusion model.
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On the cover: Defeating a complex disease like cancer will require a united, concerted
effort by different types of people from diverse backgrounds who can bring together
distinctive experiences and ways of thinking. This issue of Cancer Cell features Voices, Letter, and Commentary pieces discussing the importance of diversity
and immigration for the future of cancer research.
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On the cover: Fitzsimons et al. present a comprehensive pan-cancer single-cell RNA-seq atlas of intratumoral B cells,
revealing key associations with responses to immune checkpoint inhibitor therapy and
placing these findings in a spatial context. The cover artwork depicts the identification
of B cells within the tumor microenvironment, illustrating the high-resolution phenotyping
of distinct B cell subsets.
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MAC_Bench/Cell/Story/Cancer Cell/42_3.txt
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groundtruth
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On the cover: After one of the most challenging years marked by the COVID-19 pandemic
and a call for social change to eliminate racism and increase diversity and equity
in science, we want to bring hope for 2021. This issue of Cancer Cell features a Voices
(pp. 1–2) discussing lessons learned in 2020 and upcoming changes in cancer research
and oncology to shine some light on the future ahead.
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Trends in Microbiology
|
32_3
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Trends in Microbiology/32_3.png
|
C
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This themed issue of Trends in Microbiology examines the role that metabolism plays
in microbial life ranging from how microbes obtain energy to how microbes can alter
the metabolism of their host and use host-derived metabolites to their advantage.
The cover image was inspired by the hypothesis that perhaps pathogenic bacteria might
just be looking for food, which is discussed by Rohmer et al. on pages 341–348. Cover
image courtesy Rodolphe ‘Rodho’ Grandviennot.
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On pages 376–382, Yves Dufrêne examines the forces that drive cell adhesion and biofilm
formation as well as how atomic force microscopy is increasingly used to measure these
forces. The cover features an atomic force microscopy image of a flagellated Bacillus thuringiensis bacterium on a surface. Image courtesy Annika Gillis, Vincent Dupres, Jacques Mahillon,
and Yves Dufrêne.
|
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Pathogenic Cryptococcus species are frequently isolated from diverse
environments worldwide. These human opportunistic pathogens are often associated
with bird excreta and plant material. Given the complexity of the Cryptococcus ecology,
in this issue, Magnus Hallas-Møller and colleagues have explored data from diverse
and
interrelated disciplines to better define natural hosts and growth sites of this fungus.
Especially given their lack of enzymatic machinery to degrade cellulose, Cryptococcus
species appear to be benign commensals on or in plants. However, the enhancement of
Cryptococcus mating by plant-derived material and their frequent environmental isolation
from vegetation argue for complex, inter-kingdom interactions between plants and these
human fungal pathogens. The cover art shows Cryptococcus neoformans on a Eucalyptus
leaf. The fungal cells (pink) nestle among waxy elongated epidermal cells (purple)
directly
on a vascular bundle close to guard cells (yellow) and basal epidermal cells (green).
Image courtesy: Helle Jakobe Martens, CloseUpImaging, Copenhagen.
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MAC_Bench/Cell/Story/Trends in Microbiology/32_3.txt
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groundtruth
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32_3.txt
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The microbial cell is heterogeneous and decorated with appendages, proteins and polysaccharides.
On pages 389–397, Dupres et al. discuss the organization of the different components
of microbial cell envelopes as has been revealed using single cell techniques such
as atomic force microscopy and variations of this. Shown on the cover is a three-dimensional
atomic force microscopy image of a living Saccharomyces cerevisiae cell. Cover image
courtesy Yves Dufrêne.
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MAC_Bench/Cell/Story/Trends in Microbiology/18_4.txt
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vith
|
18_4.txt
|
val
|
NATURE REVIEWS MOLECULAR CELL BIOLOGY
|
25_7
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/25_7.png
|
B
|
RNA tailing is the addition of non-templated nucleotides to the 3′ end of RNA. To learn about non-canonical RNA tails and how human terminal nucleotidyltransferases modify RNAs post-transcriptionally to control RNA stability and activity, read the Review by Yu & Kim.
Cover design: Vicky Summersby
|
MAC_Bench/Nature/Story/NATURE REVIEWS MOLECULAR CELL BIOLOGY/21_4.txt
|
clip
|
21_4.txt
|
‘Iron-dependent cell death’, inspired by the Review on p424
Cover design: Vicky Summersby
|
MAC_Bench/Nature/Story/NATURE REVIEWS MOLECULAR CELL BIOLOGY/25_7.txt
|
groundtruth
|
25_7.txt
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‘Understanding cell fate decisions’, inspired by the Review on p11
Cover design: Vicky Summersby
|
MAC_Bench/Nature/Story/NATURE REVIEWS MOLECULAR CELL BIOLOGY/26_1.txt
|
vith
|
26_1.txt
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‘Cell death in the Iron Age’ (ferroptosis), inspired by the Review on p266
Cover design: Vicky Summersby
|
MAC_Bench/Nature/Story/NATURE REVIEWS MOLECULAR CELL BIOLOGY/22_9.txt
|
vitg
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22_9.txt
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train
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Caner Cell
|
42_5
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Caner Cell/42_5.png
|
A
|
On the cover: Sun et al. characterize the mechanistic significance and diagnostic potential of plasma and
fecal metabolites in colorectal cancer (CRC). The cover artwork depicts the journey
of sailboats, symbolizing CRC progression. The dolphins (representing inhibitory metabolites
like allocholic acid) swim alongside a boat veering away from a storm, while sharks
(representing promoting metabolites like oleic acid) follow a boat heading into the
storm. A buoy at the diverging paths signifies early tumor diagnosis based on metabolite
analysis. Image credit: Jun Yu.
|
MAC_Bench/Cell/Story/Caner Cell/42_5.txt
|
groundtruth
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42_5.txt
|
On the cover: After one of the most challenging years marked by the COVID-19 pandemic
and a call for social change to eliminate racism and increase diversity and equity
in science, we want to bring hope for 2021. This issue of Cancer Cell features a Voices
(pp. 1–2) discussing lessons learned in 2020 and upcoming changes in cancer research
and oncology to shine some light on the future ahead.
|
MAC_Bench/Cell/Story/Caner Cell/39_12.txt
|
vitg
|
39_12.txt
|
On the cover: As Cancer Cell celebrates 10 years of publishing groundbreaking cancer
research, we reflect on the dramatic progress that has been made. The previous decade
has witnessed leaps forward in the understanding of the genetic, epigenetic, and metabolic
alterations in cancer cells, tumor heterogeneity, and the importance of the host in
tumor progression and therapy response. Experimental approaches such as RNA interference,
animal models, DNA sequencing, “omics,” and rational drug design have advanced tremendously
and greatly facilitated discovery. Several exciting new cancer therapeutics were approved
in the last decade. Encouraged by the achievements of the past decade, we look ahead
with excitement to the next 10 years of progress. Cover image by Scott Armstrong and
Eric D. Smith.
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MAC_Bench/Cell/Story/Caner Cell/21_4.txt
|
vith
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21_4.txt
|
On the cover: Defeating a complex disease like cancer will require a united, concerted
effort by different types of people from diverse backgrounds who can bring together
distinctive experiences and ways of thinking. This issue of Cancer Cell features Voices, Letter, and Commentary pieces discussing the importance of diversity
and immigration for the future of cancer research.
|
MAC_Bench/Cell/Story/Caner Cell/38_4.txt
|
clip
|
38_4.txt
|
train
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One Earth
|
7_6
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/One Earth/7_6.png
|
D
|
On the cover: Soil, the earth beneath our feet, provides essential ecological services
for all life on Earth, but it is under immense pressure from anthropogenic activities.
Yet before we can effectively manage, protect, and restore our soils, we must first
develop a comprehensive understanding of soil health. Getty, Kami (Kuo, Jia-Wei).
|
MAC_Bench/Cell/Story/One Earth/7_1.txt
|
clip
|
7_1.txt
|
On the cover: Protecting the planet against further harm is critical, now more than
ever. To address the complex, interrelated, socio-environmental challenges threatening
societies and ecosystems, we need governance for sustainability. Image credit: Baac3nes
via Getty Images.
|
MAC_Bench/Cell/Story/One Earth/5_7.txt
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ave_2
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5_7.txt
|
On the cover: The inaugural issue of One Earth focuses on climate action. Climate change is arguably the defining challenge of our
time, but more importantly, it is our inaction that will jeopardize the well-being
of future generations. Here, our cover depicts the generation at risk and their awareness
of, and engagement with, the climate issue while also reinterpreting the UN Sustainable
Development Goals' call for climate action icon (SDG 13).
|
MAC_Bench/Cell/Story/One Earth/1_4.txt
|
vitg
|
1_4.txt
|
On the cover: Land is a finite resource, yet as the human population grows our demands
on land are ever increasing. Parcels of land have undergone multiple transformations,
and unsustainable land management practices have negatively impacted both people and
planet. Cover: Development plans on rural valley. Rupert King, Getty.
|
MAC_Bench/Cell/Story/One Earth/7_6.txt
|
groundtruth
|
7_6.txt
|
val
|
Journal of the American Chemical Society
|
2024_30
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_30.png
|
A
|
Manipulating the cation composition of layered, P2-type Na2/3Ni1/3Mn2/3O2 with Li or Mn alters the interlayer cation ordering. The distinct interlayer arrangements of honeycomb-ordered transition metal layers significantly impact the Na+/vacancy ordering and diffusion. These insights provide design strategies for high-power, sustainable electrode materials to support renewable energy storage. View the article.
|
MAC_Bench/ACS/Story/Journal of the American Chemical Society/2024_30.txt
|
groundtruth
|
2024_30.txt
|
Through massive molecular dynamics simulations, it was found that the fluorine domain endows fluorinated ionic liquids ultrahigh solubility of nitrogen. Meanwhile, a theoretical model of fluorine densification energy was also constructed to predict the abnormal solubility of nitrogen based on the microscopic structure of fluorinated ionic liquids. View the article.
|
MAC_Bench/ACS/Story/Journal of the American Chemical Society/2024_15.txt
|
clip
|
2024_15.txt
|
A flow platform has been developed for the rapid assembly of polypeptides through native chemical ligation coupled with a novel photodesulfurization transformation. This technology was used to prepare the clinically approved HIV therapeutic enfuvirtide and the diagnostic agent somatorelin 2 orders of magnitude faster than traditional batch methods. See Payne and co-workers. DOI: 10.1021/jacs.8b03115. View the article.
|
MAC_Bench/ACS/Story/Journal of the American Chemical Society/2018_23.txt
|
vitg
|
2018_23.txt
|
Mechanistic understanding of atom transfer radical polymerization (ATRP) is fundamental to predict and control polymerization outcomes and to guide the next advances in ATRP, which include using Fe catalysts, combining various stimuli, expanding the monomer and functionality scope, running it at larger or smaller scale, and developing controlled depolymerization procedures.
|
MAC_Bench/ACS/Story/Journal of the American Chemical Society/2022_18.txt
|
vith
|
2022_18.txt
|
train
|
The Journal of Physical Chemistry A
|
2025_3
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2025_3.png
|
C
|
Collage of cover art from recent issues of J. Phys. Chem. A. Background: Rationalizing the Fluorescence Behavior of Core-Substituted Naphthalene Diimides (J. Phys. Chem. A 2022, 126 (7), 1114–1122. DOI:
|
MAC_Bench/ACS/Story/The Journal of Physical Chemistry A/2023_30.txt
|
ave_2
|
2023_30.txt
|
New tools and methods for both experimental and theoretical physical chemistry are showcased in The Journal of Physical Chemistry A. These advances address topics covered by all three part– A, B, and C–of the Journal. This cover features art from recent articles that are showcased in this
|
MAC_Bench/ACS/Story/The Journal of Physical Chemistry A/2022_50.txt
|
clip
|
2022_50.txt
|
Ab initio trajectory simulations of the reaction between chloramine (NH2Cl) and methoxide ion (CH3O-) reveal a dominant proton transfer and minor SN2 products, consistent with experimental findings. Additionally, novel hydride transfer and unconventional roundabout pathways are observed in the nitrogen-centered reaction.
|
MAC_Bench/ACS/Story/The Journal of Physical Chemistry A/2025_3.txt
|
groundtruth
|
2025_3.txt
|
Collage of cover art from recent issues of J. Phys. Chem. A. Background: Hebbian Learning on Small Data Enables Experimental Discovery of High Tg Polyimides (J. Phys. Chem. A 2021, 125 (31), 6829–6835. DOI: 10.1021/acs.jpca.1c02959). Clockwise from top left: Evaluation of Electron Density Shifts in Noncovalent Interactions (J. Phys. Chem. A 2021, 125 (22), 4741–4749. DOI: 10.1021/acs.jpca.1c00830); An Aromatic Universe–A Physical Chemistry Perspective (J. Phys. Chem. A 2021, 125 (18), 3826–3840. DOI: 10.1021/acs.jpca.1c00606), image components from NASA and iStock and compiled by Andrew Turner; Tribute to Alexander I. Boldyrev (J. Phys. Chem. A 2021, 125 (42), 9261–9263. DOI: 10.1021/acs.jpca.1c08112), image by Marina Popova; Theoretical Engineering of Singlet Fission Kinetics in Perylene Bisimide Dimer with Chromophore Rotation (J. Phys. Chem. A 2021, 125 (3), 875–884. DOI: 10.1021/acs.jpca.0c08706). Center: DFT Analysis of Organotin Catalytic Mechanisms in Dehydration Esterification Reactions for Terephthalic Acid and 2,2,4,4-Tetramethyl-1,3-cyclobutanediol (J. Phys. Chem. A 2021, 125 (23), 4943–4956. DOI: 10.1021/acs.jpca.1c00850).
|
MAC_Bench/ACS/Story/The Journal of Physical Chemistry A/2022_1.txt
|
ave_1
|
2022_1.txt
|
train
|
Developmental Cell
|
59_5
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Developmental Cell/59_5.png
|
C
|
On the cover: Lineage motifs, symbolized here as ink stamps, are recurring patterns
of cell fates on lineage trees. They represent developmental modules that produce
cell types in predefined ratios during processes like retina development. Furthermore,
they could facilitate adaptive variation in cell type frequencies between species
such as rat, monkey, and chicken, as shown in the pages depicting slices of retina
generated through lineage motif stamps. To learn more about how lineage motifs act
as developmental modules for control of cell type proportions, see Tran et al. Image credit: Adara Koivula.
|
MAC_Bench/Cell/Story/Developmental Cell/59_19.txt
|
vith
|
59_19.txt
|
On the cover: The cover image depicts how cellular and molecular landmarks of early
mouse skin development (colorful stroke) can be uncovered within the seemingly uniform
embryonic skin tissue (black-and-white template). The color palette contains the single-cell-transcriptomics-derived
major cell types (depicted by their UMAP representation) that were mapped to the tissue
using multiplex RNA in situ stainings. To learn more about molecular and histological
key transitions, cross-cell type communications, and the onset of lineage diversifications
during mouse skin development, see Jacob et al. (pp. 2140–2162). Image credit: Nil
Campamà Sanz and Tina Jacob.
|
MAC_Bench/Cell/Story/Developmental Cell/58_5.txt
|
clip
|
58_5.txt
|
On the cover: The cover features a set of fluorescence microscopy images of the keratin
intermediate filament cytoskeleton network, which provides mechanical strength to
epithelial cells. The different image colors represent the many different mixtures
of keratin isoforms expressed depending on the cellular context. Images from different
time points are superimposed, providing a sense of motion. The blue and yellow panel
traces the filament paths, emphasizing their mesh-like network configuration. To learn
more about how different keratin isoforms influence epithelial cell behavior, see
Nanes et al. Image credit: Benjamin Nanes.
|
MAC_Bench/Cell/Story/Developmental Cell/59_5.txt
|
groundtruth
|
59_5.txt
|
On the cover: Developmental Cell publishes papers representing a full range of cell biology and development, from
molecular mechanism to organismal pathophysiology. The spiraling elements depicted
on the cover of this month's tenth anniversary issue suggest a continuum of relationships
amongst these intertwined disciplines. Cover image created by Kate Mahan and Yvonne
Blanco.
|
MAC_Bench/Cell/Story/Developmental Cell/21_6.txt
|
vitg
|
21_6.txt
|
train
|
Nature Geoscience
|
17_12
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Geoscience/17_12.png
|
B
|
High humidity in the warm Eocene
Early Eocene siderite spherules collected from Mount Blum, Washington State, United States, used to reconstruct past terrestrial temperature and hydroclimate conditions.
See van Dijk et al.
Image: Joep van Dijk, ETH Zürich. Cover Design: Thomas Phillips.
|
MAC_Bench/Nature/Story/Nature Geoscience/13_2.txt
|
clip
|
13_2.txt
|
Rare earth elements in circulation
Mobilization of in-use rare earth element stocks in regions of high consumption can ease dependence on regions of rare earth element extraction, according to dynamic integrated modelling combining material flow and scenario analysis. The satellite image shows wind turbines offshore Jiangsu, China, that have magnets containing substantial rare earth elements, representing a potential urban mine for reuse.
See Chen et al.
Image: Chang Guang Satellite Technology. Cover design: Alex Whitworth
|
MAC_Bench/Nature/Story/Nature Geoscience/17_12.txt
|
groundtruth
|
17_12.txt
|
Interactions between narrow frontal currents and topography in the Drake Passage enhance bottom mixing, according to ocean glider observations. Such interactions between frontal currents and topography could help close Southern Ocean overturning. This image shows Neumayer Channel near the northwestern coast of the Antarctic Peninsula.
Article p840; News & Views p806
IMAGE: XIAOZHOU RUAN
COVER DESIGN: TULSI VORALIA
|
MAC_Bench/Nature/Story/Nature Geoscience/10_2.txt
|
vitg
|
10_2.txt
|
Holocene temperature trends in the Arctic are unclear. An isotope record from ice wedges in Siberia suggests that winters have warmed since the mid-Holocene, whereas summer temperatures have cooled. The image shows a Pleistocene ice wedge on Muostakh Island, North Siberia, in August 2012.
Letter p122
IMAGE: THOMAS OPEL
COVER DESIGN: DAVID SHAND
|
MAC_Bench/Nature/Story/Nature Geoscience/8_11.txt
|
ave_1
|
8_11.txt
|
val
|
JACS Au
|
2024_12
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/JACS Au/2024_12.png
|
C
|
Following a cancer-stem-cell phenotype approach, the discovery of the synthetic small molecule UCM-13369, inspired by microbiota metabolites, is disclosed. Targeting NPM1 protein, the new inhibitor triggers apoptosis in cells from acute myeloid leukemia patients and reduces tumor infiltration in mice. UCM-13369 represents a therapeutic opportunity for NPM1-mutated leukemia, a high-mortality disease. The cover image was created using the generative AI program Midjourney.
|
MAC_Bench/ACS/Story/JACS Au/2024_8.txt
|
vith
|
2024_8.txt
|
The membrane-bound phospholipase A1 from Pseudomonas aeruginosa is a potential drug target. PlaF remodels membrane glycerophospholipids, influencing virulence-associated signaling. Medium-chain free fatty acids, products of PlaF action, inhibit its activity. Molecular simulations and free energy computations uncover how fatty acids control PlaF. For this image, an author-made hand drawing was refined with GPT-4.
|
MAC_Bench/ACS/Story/JACS Au/2024_10.txt
|
clip
|
2024_10.txt
|
CO3 layer undergoes direct carbonate hydrogenation with limited decomposition, pointing out a new path for gas-solid CO2 upgradation.
|
MAC_Bench/ACS/Story/JACS Au/2024_12.txt
|
groundtruth
|
2024_12.txt
|
A PdZn/ZrO2/SAPO-34 multifunctional catalyst for the direct conversion of CO2 to propane yields >50% total propane selectivity at close to 40% CO2 conversion at 350 ⁰C, 50 bar, and 1500 mL g−1 h−1. Extensive characterization and kinetic–thermodynamic modeling revealed details of a highly integrated reaction scheme between the catalyst components.
|
MAC_Bench/ACS/Story/JACS Au/2021_3.txt
|
vitg
|
2021_3.txt
|
val
|
Trends in Cognitive Sciences
|
28_11
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/28_11.png
|
B
|
In this issue of Trends in Cognitive Sciences, Decety and Yoder describe emerging findings on the cognitive and neuroscientific
underpinnings of justice motivation. Cover image from iStockphoto/tomloel. Cover design
by Rebecca Schwarzlose.
|
MAC_Bench/Cell/Story/Trends in Cognitive Sciences/21_12.txt
|
clip
|
21_12.txt
|
Psychological traits, including emotions, values, social behaviors, and
personality, exhibit variability across historical periods. These traits are reflected
in
the cultural artifacts of different periods. However, until recently, psychologists
have
largely lacked the tools needed to systemically analyze these ‘cultural fossils’.
In this
issue of Trends in Cognitive Sciences, Nicholas Baumard and colleagues review how
recent computational advances are being used to systematically explore variability
in
cultural fossils, including the literature, paintings, and music of different periods,
and
what this variability may tell us about the values and preferences of different cultures.
For example, the authors examine how variations in depictions of children in paintings
may illuminate parental attitudes throughout different historical periods. Cover image:
Manuel Osorio Manrique de Zuñiga (1784–1792) by Goya.
|
MAC_Bench/Cell/Story/Trends in Cognitive Sciences/28_11.txt
|
groundtruth
|
28_11.txt
|
In celebration of the 20th anniversary of Trends in Cognitive Sciences, this issue highlights how human cognition interacts with the modern environment.
The editorial introduces a virtual special issue on cognition in the modern era and
highlights articles in this and recent issues that examine facets of this topic. Cover
image from iStockphoto/studiogstock. Cover design by Rebecca Schwarzlose.
|
MAC_Bench/Cell/Story/Trends in Cognitive Sciences/21_11.txt
|
vith
|
21_11.txt
|
In celebration of our 25th anniversary, this issue of Trends in Cognitive Sciences features a series of essays highlighting key open questions that leading scientists
believe the field should explore over the next quarter-century. Reflecting the breadth
of cognitive science, these essays address diverse topics, from episodic memory to
developmental psychology, consciousness to auditory cognition, and the experience
of pain to mind-culture interactions. The real-world applicability of cognitive science,
the interface between cognitive science and artificial intelligence, and the use of
paradigms and methods that capture the dynamics of naturalistic cognition emerge as
key themes. The puzzle pieces on the cover, depicting previous TICS covers, represent the process of knowledge accumulation over the last 25 years. Artwork
by Phillip Krzeminski.
|
MAC_Bench/Cell/Story/Trends in Cognitive Sciences/26_1.txt
|
vitg
|
26_1.txt
|
test
|
Science Signaling
|
2007_388
|
Which of the following options best describe the cover image?
|
MAC_Bench/Science/Cover/Science Signaling/2007_388.png
|
A
|
COVER This week's Focus Issue, published to complement the Science Special Issue on Single Molecules contains an Editorial Guide as well as three Perspectives that discuss technical advances that allow cell signaling researchers to zoom in on individual molecules. [Image: Christopher Bickel, AAAS]
|
MAC_Bench/Science/Story/Science Signaling/2007_388.txt
|
groundtruth
|
2007_388.txt
|
ONLINE COVER This week features a Research Resource that describes a technique by which cells can be engineered to bind to apoptotic cells and then internalize them, thus making nonphagocytic cells become phagocytic. The image depicts the engulfment of apoptotic cells (pink) by an engineered phagocytic cell (blue). [Image: Chris Bickel, AAAS]
|
MAC_Bench/Science/Story/Science Signaling/7_334.txt
|
vitg
|
7_334.txt
|
ONLINE COVER This week features a Research Article that shows that the mitochondrial Ca2+ uniporter enables ATP production to match energy demands during the cell cycle. The image shows an artist's rendition of a mitotic cell. [Image: MedicalRF/Science Source]
|
MAC_Bench/Science/Story/Science Signaling/12_579.txt
|
clip
|
12_579.txt
|
COVER This week's Focus Issue highlights mechanisms of gene regulation (see the Editorial Guide). Articles and resources at Science Signaling focus on some of the mechanisms that control various aspects of gene expression before, during, and after transcription. The image depicts an artist's rendition of gene expression. [Image: Carin L. Cain]
|
MAC_Bench/Science/Story/Science Signaling/1_13.txt
|
vith
|
1_13.txt
|
train
|
Molecular Therapy
|
32_4
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Molecular Therapy/32_4.png
|
C
|
On the Cover: The image is an artistic presentation of the PeptiENV platform described in Ylösmäki
et al., pp. 2315–2325. The metallic grey/blue-ish particles represent an enveloped
virus and the white, green, and purple “string of beads” represents the attached therapeutic
peptides. This is a very simple yet effective method of increasing the tumor-specific
T cell responses of clinically relevant enveloped viruses.
|
MAC_Bench/Cell/Story/Molecular Therapy/26_4.txt
|
ave_1
|
26_4.txt
|
On the Cover: This special issue of Molecular Therapy is devoted to the topic of nanoparticle development for gene and cell therapies,
edited by invited guest editors S. Moein Moghimi and Ernst Wagner. The cover represents
an artistic view of receptor-mediated endocytosis of a ligand-decorated synthetic
nanoparticle into a cell, followed by intracellular endosome disruption, based on
the process of viral cell entry that scientists try to exploit or mimic during the
design of nanoparticle systems. Cover credit: Christoph Hohmann, Nanosystems Initiative
Munich (NIM).
|
MAC_Bench/Cell/Story/Molecular Therapy/25_6.txt
|
vitg
|
25_6.txt
|
On the cover: The cover is an abstract photograph capturing many and various marvels at the Gardens
by the Bay in Singapore. It symbolizes the variety of targets to be discovered in
the field of cell and gene therapy and the hazy complexity of the methodologies aimed
at their identification. Image credit: Pierluigi Di Pietro.
|
MAC_Bench/Cell/Story/Molecular Therapy/32_4.txt
|
groundtruth
|
32_4.txt
|
On the Cover: This issue of Molecular Therapy is the first of its 20th year of publication. The field of gene and cell therapy has changed significantly
during these two decades: the science has led to real therapies that are now beginning
to impact patients. Many issues remain to be solved, however, if these promising molecular
therapies are to become affordable and accessible treatment options for both patients
and medical providers. Molecular Therapy and its sibling journals look forward to covering these important issues in the decades
to come. Cover credit: iStock.com/YinYang.
|
MAC_Bench/Cell/Story/Molecular Therapy/27_14.txt
|
clip
|
27_14.txt
|
val
|
Nature Chemistry
|
17_1
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Chemistry/17_1.png
|
D
|
The cover image shows an artistic impression of large single crystals comprising covalent organic networks. A team led by James Wuest made these materials through the reversible polymerization of organic monomers bearing four tetrahedrally oriented nitroso groups and characterized them using single-crystal X-ray diffraction. Such a modular construction is typically used to build monocrystalline materials held together by non-covalentbonding interactions, but is now also shown to work for covalently bonded analogues.
Article p830; News & Views p810
IMAGE: SOPHIE DUBOIS ONCE UPON A TIME IN THE LAB (ORIGINAL PAINTING: ACRYLIC ON CANVAS, 2012).
COVER DESIGN: ALEX WING
|
MAC_Bench/Nature/Story/Nature Chemistry/5_3.txt
|
clip
|
5_3.txt
|
Complex terpene natural products are assembled in nature by reaction cascades that occur inside enzyme pockets that stabilize the cationic intermediates and transition states. Now Qi Zhang and Konrad Tiefenbacher have successfully mimicked this process inside a supramolecular assembly. As shown on the cover, six resorcinarene monomers self-assemble to form a cavity that can encapsulate a geranyl acetate substrate and catalyse its conversion to a variety of cyclic monoterpene natural products.Article p197;News & Views p187IMAGE: JOHANNES RICHERSCOVER DESIGN: ALEX WING
|
MAC_Bench/Nature/Story/Nature Chemistry/7_10.txt
|
ave_2
|
7_10.txt
|
The cover image shows a surface-confined switch based on an electroactive organic radical (red) that is transformed to the corresponding anion (purple). This bistable system, developed by Jaume Veciana, Concepció Rovira and co-workers, behaves as an extremely robust redox switch in which an electrical input is transduced into an optical and magnetic output. This switch operates at very low voltages, can be patterned and locally addressed, and exhibits an exceptionally high long-term stability and excellent reversibility.
Image by Mateu Marcet/Cover design by Alex Wing, Nature Chemistry
Article p359
|
MAC_Bench/Nature/Story/Nature Chemistry/3_8.txt
|
ave_1
|
3_8.txt
|
Chiroptical ionic co-crystals
The co-crystallization of nanoclusters with functional organic molecules can provide access to superlattices with unique properties; however, this process remains synthetically challenging. Now, a team led by Jarad A. Mason has shown that silver nanoclusters and organic macrocycles can be assembled through a supramolecular approach into ionic co-crystals with tunable structures that exhibit large chiroptical effects. The cover shows the structure of enantiopure chiral co-crystals featuring atomically precise silver nanoclusters and organic macrocycles.
See Mason et al.
Image: Dr. Yingwei Li, Harvard University. Cover design: Tulsi Voralia
|
MAC_Bench/Nature/Story/Nature Chemistry/17_1.txt
|
groundtruth
|
17_1.txt
|
train
|
Lab Animal
|
53_1
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Lab Animal/53_1.png
|
C
|
Refining the housing and husbandry of laboratory rats
Housing and husbandry conditions are known to affect animal welfare and research outcomes. In a new article, Neville et al. conducted a mapping review of refinements to laboratory rat housing and husbandry, and identified specific interventions that are likely to generate welfare improvements.
See Neville et al.
COVER IMAGE: Marina Spence. COVER DESIGN: Marina Spence.
|
MAC_Bench/Nature/Story/Lab Animal/52_10.txt
|
clip
|
52_10.txt
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Finding zebrafish in the field
Studying zebrafish in their natural habitats can help inform how the model organisms are studied and reared in research facilities, but finding the real wild types means stepping far outside the lab.
Depicted on the cover is a shallow pool of turbid water, running over bedrock, lime, and silt, that connects to the Kaveri River in Kallahalli, India. Here, a field trip to study the natural acoustic properties of zebrafish habitats found fish swimming in loose shoals of 5 to 10 individuals.
See Neff
IMAGE: Rafael A. Lara and Raquel O. Vasconcelos. COVER DESIGN: Erin Dewalt.
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vitg
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49_1.txt
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Digging deeper into the marble burying task
The marble burying task (MBT) is widely used to measure anxiety-like behavior in rodent models, but it is not typically video-recorded. In our first Brief Communication, Burgett et al. show that using a single photo at the end of the task might not be a reliable indicator of rodent engagement with marbles. The authors suggest that video analysis might provide a more accurate representation of the rich set of behaviors displayed in the MBT.
See Burgett et al.
Cover image: Marina Spence. Cover design: Marina Spence
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MAC_Bench/Nature/Story/Lab Animal/53_1.txt
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groundtruth
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53_1.txt
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50 years of Lab Animal
We’ve gone retro this month to celebrate Lab Animal’s 50th Anniversary! 1971 saw the very first issue of the long-running journal, which has grown to encompass animal research from vivarium to lab bench and everywhere in between and features an ever-growing menagerie of model species. Here’s to 50 more years!
See Editorial
IMAGE: Marina Spence. COVER DESIGN: Marina Spence.
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The Journal of Physical Chemistry C
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2025_2
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Which of the following options best describe the cover image?
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MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2025_2.png
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D
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Collage of cover art from recent issues of J. Phys. Chem. C. Background: Role of Molecular Simulations in the Design of Metal–Organic Frameworks for Gas-Phase Thermocatalysis: A Perspective (J. Phys. Chem. C 2022, 126 (14), 6111–6118. DOI: 10.1021/acs.jpcc.1c10778). Counter-clockwise from middle left: Molecularly Designed Cluster–Surface Interaction for Halogen-like and Alkali-like Metal-Encapsulating Silicon Cage Superatoms on n- and p-Type Organic Substrates (J. Phys. Chem. C 2022, 126 (26), 10889–10899. DOI: 10.1021/acs.jpcc.2c02196), image by Takashi Tsujino; Ligand-Structure-Dependent Coherent Vibrational Wavepacket Dynamics in Pyrazolate-Bridged Pt(II) Dimers (J. Phys. Chem. C 2022, 126 (28), 11487–11497. DOI: 10.1021/acs.jpcc.2c02256); Understanding the Photoelectrochemical Behavior of Metal Nanoclusters: A Perspective (J. Phys. Chem. C 2022, 126 (40), 16928–16942. DOI: 10.1021/acs.jpcc.2c05301); Understanding the Phase Equilibrium and Kinetics of Electrochemically Driven Phase Transition in CoOxHy during Electrocatalytic Reactions (J. Phys. Chem. C 2022, 126 (43), 18198–18207. DOI: 10.1021/acs.jpcc.2c04813).
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MAC_Bench/ACS/Story/The Journal of Physical Chemistry C/2023_4.txt
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Collage of artwork from recent issues of J. Phys. Chem. C. Background: Light-Induced Increase of the Local Molecular Coverage on a Surface (J. Phys. Chem. C 2024, 128 (14), 5919–5926. DOI: 10.1021/acs.jpcc.4c00559). Clockwise from top left: Effects of Pore Arrangement of TiO2-Coated Porous Alumina Membranes on Photocatalytic Properties (J. Phys. Chem. C 2024, 128 (15), 6478–6486. DOI: 10.1021/acs.jpcc.4c01029); Quantum Dot Fluorescent Imaging: Using Atomic Structure Correlation Studies to Improve Photophysical Properties (J. Phys. Chem. C 2024, 128 (9), 3632–3640. DOI: 10.1021/acs.jpcc.3c07367); Ultrafast Energy Funneling in Two-Dimensional Mixed-Halide Perovskites Caused by Intrinsic Halide Immiscibility (J. Phys. Chem. C 2024, 128 (1), 279–286. DOI: 10.1021/acs.jpcc.3c07170). In Situ Tracked Hybridization Phenomenon of Gold Nanorods in Monolayer Systems (J. Phys. Chem. C 2024, 128 (14), 6065–6071. DOI: 10.1021/acs.jpcc.3c08164); Tailoring the Reaction Pathway for Control of Size and Composition of Silver–Gold Alloy Nanoparticles (J. Phys. Chem. C 2024, 128 (21), 8660–8671. DOI: 10.1021/acs.jpcc.4c00321).
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MAC_Bench/ACS/Story/The Journal of Physical Chemistry C/2025_9.txt
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Collage of cover art from recent issues of J. Phys. Chem. C. Background: Mechanistic Study of the Effect of Epoxy Groups on Ethylene Carbonate Decomposition Reaction on Carbon Anodes of Sodium-Ion Batteries (J. Phys. Chem. C 2021, 125 (15), 8031–8044. DOI: 10.1021/acs.jpcc.0c10702). Clockwise from top left: Type-I CdSe/ZnS Heteronanoplatelets Exhibit Enhanced Photocatalytic Hydrogen Evolution by Interfacial Trap-Mediated Hole Transfer (J. Phys. Chem. C 2021, 125 (43), 23945–23951. DOI: 10.1021/acs.jpcc.1c07390); Tuning the Sheet Resistance, Ferromagnetism, and H2O2 Sensitivity of ITO Film by Introducing Tunable Pores (J. Phys. Chem. C 2021, 125 (18), 10159–10164. DOI: 10.1021/acs.jpcc.1c02583); Tunable and Well-Defined Bimodal Porous Model Electrodes for Revealing Multiscale Structural Effects in the Nonaqueous Li–O2 Electrode Process (J. Phys. Chem. C 2021, 125 (2), 1403–1413. DOI: 10.1021/acs.jpcc.0c10446); Determination of Singlet Oxygen Quantum Yield of a Porphyrinic Metal–Organic Framework (J. Phys. Chem. C 2021, 125 (13), 7392–7400. DOI: 10.1021/acs.jpcc.1c00310).
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MAC_Bench/ACS/Story/The Journal of Physical Chemistry C/2022_51.txt
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2022_51.txt
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The cover art depicts an isolated hydroxyl-bridged tricopper triangular complex being lifted from the kagomé lattice of herbertsmithite, illustrating how our new compound, CaCu(OH)3Cl, represents a chemically equivalent zero-dimensional analogue of this well studied quantum spin liquid candidate. View the article.
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MAC_Bench/ACS/Story/The Journal of Physical Chemistry C/2025_2.txt
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groundtruth
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train
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Nature Reviews Chemistry
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8_3
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Which of the following options best describe the cover image?
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MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_3.png
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A
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How life arose on Earth starting from simple chemicals remains an open question — one to which we may never have a definitive answer. A shift from simple building blocks to systems that display the essential characteristics of life — confinement, metabolism, and replication — would have been necessary, ultimately coming together in conditions that are far-from-equilibrium. For a discussion of this transition, see Singh et al.
Image: Dibyendu Das; Cover design: Susanne Harris
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MAC_Bench/Nature/Story/Nature Reviews Chemistry/8_3.txt
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groundtruth
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8_3.txt
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Autocatalytic lipids — that form assemblies capable of catalysing their own formation — are fascinating chemicals that display a variety of extraordinary behaviour up to and including the emulation of processes, such as growth, metabolism and homeostasis, that are associated with living systems. The cover illustrates this with the gradual appearance from top left of ever more complex assemblies eventually leading to larger assemblies that are beginning to divide. See Howlett & Fletcher
Image: Carl Conway & Philip Patenall Cover design: Philip Patenall
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MAC_Bench/Nature/Story/Nature Reviews Chemistry/7_3.txt
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vith
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7_3.txt
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Metal–ligand interactions are widely exploited for the design of new drugs. An atomistic understanding of metal-mediated interactions, provided by powerful computational approaches, will aid the design of both potent metalloenzyme inhibitors and metal-containing drugs. See De Vivo, M. et al.
Image: Laura Riccardi. Cover Design: Rachael Tremlett.
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MAC_Bench/Nature/Story/Nature Reviews Chemistry/2_6.txt
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vitg
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2_6.txt
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The availability of synthetic DNA is outstripped by its growing number of uses. With applications in engineering biology, therapy, data storage and nanotechnology, the demand for synthetic DNA is increasing. New technologies have been developed and commercialised to meet this need. By analogy to the advances in word processing, this cover image represents how technological advances can improve the efficiency and scale of DNA syntheses. See Hoose et al.
Image: Carl Conway. Cover design: Carl Conway
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MAC_Bench/Nature/Story/Nature Reviews Chemistry/7_10.txt
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clip
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7_10.txt
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test
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Molecular Plant
|
18_3
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Which of the following options best describe the cover image?
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MAC_Bench/Cell/Cover/Molecular Plant/18_3.png
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C
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On the cover: The cover image illustrates that Artificial Intelligence (AI) technology such as
the recently developed protein structure prediction tool AlphaFold2 can be used not
only for understanding the complex interactions between plants and microorganisms
but also for designing crop varieties that can adapt to future environments. Plant
pectin methylesterase inhibitors (PMEIs) influence pathogen susceptibility and plant
growth by regulating pectin methyl esterification. However, constitutive expression
of PMEIs can disrupt cell-wall composition, leading to significant tradeoffs between
growth and defense. In this issue, Xia et al. employed AlphaFold tools to redesign
a modified soybean pectin methylesterase inhibitor protein that specifically targets
and inhibits pectin methylesterases (PMEs) of Phytophthora sojae, without affecting the developmental functions of plant PMEs, thereby conferring
enhanced disease resistance in soybean. The Image by Yeqiang Xia with the assistance
of AI: Bing images, chatgpt4/DALL. E and Photoshop software.
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MAC_Bench/Cell/Story/Molecular Plant/17_4.txt
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vitg
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17_4.txt
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On The Cover A highly conserved recognition mechanism of plant peptide hormones by their receptors,
the leucine-rich repeat receptor kinases (LRR-RKs). Image by: Heqiao Zhang and Jijie
Chai.
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MAC_Bench/Cell/Story/Molecular Plant/9_2.txt
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ave_0
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9_2.txt
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On the cover: In this issue, Lei et al. explore the regulatory role of the long non-coding RNA
ALEX1 in enhancing the resistance of rice to bacterial infections through its interaction
with ARF3. Under normal conditions, ALEX1 is expressed at low levels, allowing ARF3 to aggregate into solid-like condensates,
representing an inactive or “non-functional” phase state. However, upon pathogen infection,
ALEX1 expression is upregulated, and it binds directly to the MR domain of ARF3, facilitating
its dimerization and preventing condensate formation. This transition maintains an
active ARF3 pool, which represses the transcription of JAZ13 and activates the jasmonic acid (JA) pathway, thereby enhancing plant defense. The
cover image depicts the dynamic interplay between ALEX1 and ARF3 in modulating rice immunity. ALEX1 is portrayed as a bow, symbolizing its role in activating ARF3, represented by arrows.
The quiver on the angel's back, filled with blue arrows, signifies ARF3 in its non-functional
condensate state. This visual metaphor highlights how ALEX1 enables ARF3 transition to a functional state, orchestrating plant defense responses
against bacterial pathogens. Image by Meng-Qi Lei, Yang Yu and Yue-Qin Chen.
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MAC_Bench/Cell/Story/Molecular Plant/18_3.txt
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groundtruth
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18_3.txt
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On The Cover A single gene generates two transcription factors SUSSIBA1 and SUSIBA2 via two alternative
promotors and orchestrates the sucrose-coordinated synthesis of starch and fructan
in barley. Image by: Chuanxin Sun.
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MAC_Bench/Cell/Story/Molecular Plant/10_1.txt
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clip
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10_1.txt
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val
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Nature Reviews Electrical Engineering
|
1_1
|
Which of the following options best describe the cover image?
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MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_1.png
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C
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In alignment with UN Sustainable Development Goal 9, it is crucial to develop advanced spintronic technologies for low-power, beyond-CMOS devices. In this Focus Issue, we discuss the challenges and potential solutions in spintronics for neuromorphic computing, STT-MRAM, and logic applications. We also highlight the importance of integrating spintronic devices with existing silicon platforms and fostering collaboration between academia and industry. Additionally, we encourage the exploration of emerging materials and devices for low-power spintronics, such as two-dimensional magnets. See the Editorial
Image: Zulfidin Khodzhaev, The University of Texas at Austin Cover design: Sam Whitham
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MAC_Bench/Nature/Story/Nature Reviews Electrical Engineering/1_2.txt
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clip
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1_2.txt
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Textile displays are promising for next-generation displays owing to their capabilities of weaving electroluminescent units directly into the interwoven points of polymer composite fibres. The cover image shows the textile display. See Wang et al.
Cover design: Sam Whitham
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MAC_Bench/Nature/Story/Nature Reviews Electrical Engineering/1_6.txt
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vitg
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1_6.txt
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Photonic-crystal surface-emitting lasers is an emerging lasing technology that possess high brightness and high functionalities, while maintaining the merits of semiconductor lasers. The illustration depicts a train of pulsed laser beams emitted from the surface of a Photonic-crystal surface-emitting laser. See Noda.
Image: Susumu Noda, Kyoto University. Cover design: Sam Whitham.
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MAC_Bench/Nature/Story/Nature Reviews Electrical Engineering/1_1.txt
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groundtruth
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1_1.txt
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3D integration of 2D electronics presents an alternative platform for addressing the scaling challenges inherent in silicon-based electronics. Furthermore, this approach facilitates the realization of multifunctional capabilities within a vertically integrated system. The cover image depicts a 3D integrated chip constructed from 2D materials, which enables multifunctionalities such as sensing, logic, and memory. See Das et al.
Image: Jennifer M McCann, Subir Ghosh, Saptarshi Das, The Pennsylvania State University. Cover design: Sam Whitham
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MAC_Bench/Nature/Story/Nature Reviews Electrical Engineering/1_8.txt
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ave_2
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1_8.txt
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train
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The Journal of Physical Chemistry B
|
2025_2
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2025_2.png
|
D
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10.1021/acs.jpcb.8b12126
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MAC_Bench/ACS/Story/The Journal of Physical Chemistry B/2020_43.txt
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ave_1
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2020_43.txt
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10.1021/acs.jpcb.8b12126
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MAC_Bench/ACS/Story/The Journal of Physical Chemistry B/2020_38.txt
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ave_2
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2020_38.txt
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10.1021/acs.jpcb.8b12126
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MAC_Bench/ACS/Story/The Journal of Physical Chemistry B/2020_50.txt
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clip
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2020_50.txt
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The two-photon absorption of the Green Fluorescent Protein is intrinsically enhanced when utilizing quantum light. The classical and entangled two-photon absorption strengths can be differentially modulated by the protein, enabling precise control over the outcome through adjustments in its local electric field induced by a single amino acid substitution. The image is an artistic representation of the protein absorbing entangled light. Part of the image was generated by artificial intelligence using Kandinsky 2.2. View the article.
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MAC_Bench/ACS/Story/The Journal of Physical Chemistry B/2025_2.txt
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groundtruth
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2025_2.txt
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train
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NATURE REVIEWS GENETICS
|
25_1
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_1.png
|
C
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Inspired by the Focus issue starting on p485.
Cover design: Patrick Morgan.
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MAC_Bench/Nature/Story/NATURE REVIEWS GENETICS/24_5.txt
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ave_0
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24_5.txt
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Cover by Patrick Morgan. Original image sources: DNA - PhotoDisc/Getty; Stethoscope/keyboard - iStockphoto/Getty.
|
MAC_Bench/Nature/Story/NATURE REVIEWS GENETICS/19_12.txt
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clip
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19_12.txt
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Inspired by the Review on p829.
Cover design: Patrick Morgan
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MAC_Bench/Nature/Story/NATURE REVIEWS GENETICS/25_1.txt
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groundtruth
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25_1.txt
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COVER: inspired by the Perspective on p447.
Cover design: Patrick Morgan.
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MAC_Bench/Nature/Story/NATURE REVIEWS GENETICS/23_6.txt
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vith
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23_6.txt
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train
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Trends in Endocrinology & Metabolism
|
35_2
|
Which of the following options best describe the cover image?
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MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/35_2.png
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B
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This Special Issue of Trends in Endocrinology and Metabolism focuses on novel systems approaches for studying metabolic alterations in a high-throughput
scale. Leading experts review recent technological advances including analytical lipidomics
and the emerging area of in vivo lipid imaging, the genomics of voluntary exercise, cardiovascular disease and pediatric
obesity, new concepts in transcriptomics and phosphoproteomics, including new data
linking the microRNA interactome, RNA bindings proteins and the microbiome to metabolic
diseases. Cover mage is from iStockPhoto.
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MAC_Bench/Cell/Story/Trends in Endocrinology & Metabolism/26_1.txt
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26_1.txt
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Restoring functional beta cell mass is an essential step in curing
diabetes. While regenerating beta cells directly within the pancreas is an attractive
solution, its clinical translation has proven to be challenging. This month, Bourgeois
and colleagues discuss how new insights into beta cell regeneration can be used to
change diabetes therapy, shifting from “caring for” to “curing” this disorder. The
cover,
symbolizing renewal and transformation, merges a phoenix rising from its ashes with
a pancreatic islet. Cover credit: Len Degroote / Althar.be
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MAC_Bench/Cell/Story/Trends in Endocrinology & Metabolism/35_2.txt
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groundtruth
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35_2.txt
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This Special Issue of Trends in Endocrinology and Metabolism focuses on a select list of GPCRs and their pivotal roles in a wide range of metabolic
processes, including glucose homeostasis and insulin secretion, appetite, calcium-sensing,
heart rate and blood pressure, sleep, to mention only a few. Our experts review the
most recent advances in these areas and offer forward-looking insights regarding the
actions of these key GPCRs in several metabolic and endocrine disorders. Cover image
was prepared by Effie Tzameli using the structure of the human beta-2 adrenergic receptor
in complex with the partial inverse agonist carazolol, licensed under the Creative
Commons Attribution-Share Alike 3.0 Unported license. Color scheme is from an Andy
Warhol painting image from Istockphoto.
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MAC_Bench/Cell/Story/Trends in Endocrinology & Metabolism/27_5.txt
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ave_1
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27_5.txt
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This Special Issue of Trends in Endocrinology and Metabolism focuses on a select list of GPCRs and their pivotal roles in a wide range of metabolic
processes, including glucose homeostasis and insulin secretion, appetite, calcium-sensing,
heart rate and blood pressure, sleep, to mention only a few. Our experts review the
most recent advances in these areas and offer forward-looking insights regarding the
actions of these key GPCRs in several metabolic and endocrine disorders. Cover image
was prepared by Effie Tzameli using the structure of the human beta-2 adrenergic receptor
in complex with the partial inverse agonist carazolol, licensed under the Creative
Commons Attribution-Share Alike 3.0 Unported license. Color scheme is from an Andy
Warhol painting image from Istockphoto.
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MAC_Bench/Cell/Story/Trends in Endocrinology & Metabolism/27_4.txt
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vitg
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27_4.txt
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val
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Nature Reviews Rheumatology
|
20_6
|
Which of the following options best describe the cover image?
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MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_6.png
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A
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Inspired by the Review on p399.
Cover design: Steven Hall
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MAC_Bench/Nature/Story/Nature Reviews Rheumatology/20_6.txt
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groundtruth
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20_6.txt
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Key advances in rheumatology, inspired by the Year in Reviews starting on p69
Cover design: S.Harris.
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MAC_Bench/Nature/Story/Nature Reviews Rheumatology/17_11.txt
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clip
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17_11.txt
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Inspired by the Review on p449.
Cover design: S.Harris/Springer Nature Limited
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MAC_Bench/Nature/Story/Nature Reviews Rheumatology/17_5.txt
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vitg
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17_5.txt
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In our August issue: articles on IL-17 in inflammatory arthritis, cardiometabolic comorbidities in RA and PsA, T follicular helper cells and T follicular regulatory cells in rheumatic diseases and anti-citrullinated protein antibodies.
Image of skin from a patient with dermatomyositis. Image supplied by Majid Zeidi, Kristen Chen and Victoria P. Werth, University of Pennsylvania School of Medicine. Cover design: Susanne Harris.
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MAC_Bench/Nature/Story/Nature Reviews Rheumatology/15_5.txt
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vith
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15_5.txt
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train
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ACS Materials Letters
|
2024_6
|
Which of the following options best describe the cover image?
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MAC_Bench/ACS/Cover/ACS Materials Letters/2024_6.png
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D
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In the article featured on the cover, the authors report the synthesis of an ionic liquid consisting of a polymerizable methacrylate with a thermally-labile Diels−Alder linkage between the ion-containing side chain and the polymer backbone. The cover illustration shows how, under UV light, the ionic liquid can be polymerized, and can then be induced to release ions in response to a thermal trigger. This ion release results in a clear increase in mobile ion content at the retro-Diels−Alder temperature which is retained after the material is returned to room temperature. This type of "triggerable" polymerizable ionic liquid has promise in next-generation responsive electronic devices.
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MAC_Bench/ACS/Story/ACS Materials Letters/2020_9.txt
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vith
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2020_9.txt
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Atomically controlled multicomponent nanomaterials serve as platforms to advance the understanding of scientific phenomena and provide practical solutions for various applications. Featured
|
MAC_Bench/ACS/Story/ACS Materials Letters/2020_4.txt
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vitg
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2020_4.txt
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The image on the cover is an artistic representation of bright fluorescent organic materials exhibiting red, yellow, and green emission for production of organic light-emitting devices. In this issue, authors have developed a styrene-based lamellar single crystal as a versatile optoelectronic material in optical pumping and light-emitting transistors. Credit: Shutterstock.com.
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MAC_Bench/ACS/Story/ACS Materials Letters/2021_9.txt
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2021_9.txt
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Ultra-pure organic crystals do not display long-lived emission and, hence, can be perceived as essentially dark 3D frameworks. The review highlights that phosphorescence within these dark frameworks can be only achieved if tiny amounts of impurities are added. The impurities act as exciton traps and enable long-lived emission.
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MAC_Bench/ACS/Story/ACS Materials Letters/2024_6.txt
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groundtruth
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2024_6.txt
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train
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Nature Catalysis
|
7_8
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Catalysis/7_8.png
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B
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Active sites revealed
In their work, the authors present a methodology to map the active sites of nanoparticle catalysts via a combination of atomic electron tomography and first-principles-trained machine learning. This allows them to draw structure–activity relationships and propose a local environment descriptor.
See Yang et al.
Image: Yao Yang, Westlake University. Cover design: Alex Whitworth
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MAC_Bench/Nature/Story/Nature Catalysis/7_6.txt
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clip
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7_6.txt
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Bias-free ammonia
In their work, Ji-Wook Jang and colleagues couple an efficient lead halide perovskite photocathode for nitrate reduction to a glycerol oxidation anode for bias-free ammonia production with a photocurrent density greater than 20 mA cm–2.
See Tayyebi et al.
Image: CUBE3D Graphic / Younghee Lee. Cover design: Alex Whitworth
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MAC_Bench/Nature/Story/Nature Catalysis/7_8.txt
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groundtruth
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7_8.txt
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Two eyes on single particles
Weckhuysen and co-workers report a set of catalyst sensors that allow for the simultaneous detection of local temperature and surface species on catalyst particles. This provides a powerful method to monitor, characterize and understand catalytic systems.
See Hartman et al.
Image: Thomas Hartman (Utrecht University). Cover Design: Alex Wing.
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MAC_Bench/Nature/Story/Nature Catalysis/2_2.txt
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vith
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2_2.txt
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Artificial biocatalytic systems
Biocatalysis is an enabling technology for a more sustainable future. This Insight provides an overview of engineering enzymes and microbes, as well as methods for interfacing them with abiological materials to improve their performance and range of applications.
The cover comes from an Article by Julia Sanz-Aparicio, Víctor Guallar, Manuel Ferrer and co-workers on engineering enzyme scaffolds with two active sites to synergistically combine biological and new-to-nature chemical transformations.
See Alonso et al.
Image: Julia Sanz-Aparicio (CSIC). Cover Design: Valentina Monaco.
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MAC_Bench/Nature/Story/Nature Catalysis/3_10.txt
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vitg
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3_10.txt
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train
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NATURE GENETICS
|
56_10
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/NATURE GENETICS/56_10.png
|
D
|
Engineering crop polyploid genomes
Generation of clonal gametes in tomato enables polyploid genome design through controlled combination of pre-defined genome haplotypes.
See Wang et al.
Image: Rainer Franzen, Yazhong Wang and Rob Kesseler. Cover design: Tulsi Voralia
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MAC_Bench/Nature/Story/NATURE GENETICS/56_7.txt
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clip
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56_7.txt
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Mendel and memories
In celebration of the 200th anniversary of Gregor Mendel’s birth and the 30th anniversary of the launch of Nature Genetics, we look both forwards and backwards at how far the genetics field has come. This cover image is inspired by the cover of the first issue of Nature Genetics in 1992.
Image and Cover Design: Valentina Monaco.
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MAC_Bench/Nature/Story/NATURE GENETICS/54_6.txt
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vitg
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54_6.txt
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Dynamic single-cell genetic effects
A new statistical method known as GASPACHO identifies nonlinear dynamic genetic effects using single-cell RNA-sequencing data.
See Kumasaka et al.
Image: Alamy. Cover Design: Tulsi Voralia.
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MAC_Bench/Nature/Story/NATURE GENETICS/55_7.txt
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ave_2
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55_7.txt
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Brassica oleracea pan-genome
De novo genome assemblies of 22 Brassica oleracea accessions and pan-genome analyses highlight the effects of structural variation on gene expression and its contribution to morphotype diversification.
See Li et al.
Image: Chang Keyong, professional photographer, Beijing, China. Cover Design: Tulsi Voralia
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MAC_Bench/Nature/Story/NATURE GENETICS/56_10.txt
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groundtruth
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56_10.txt
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train
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NATURE REVIEWS DRUG DISCOVERY
|
23_11
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_11.png
|
A
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Extracellular targeted protein degradation, inspired by the Review on p126.
Cover design: S. Harris
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MAC_Bench/Nature/Story/NATURE REVIEWS DRUG DISCOVERY/23_11.txt
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groundtruth
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23_11.txt
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Peptide therapeutics targeting GPCRs, inspired by the Review on p389.
Cover design: Susanne Harris.
|
MAC_Bench/Nature/Story/NATURE REVIEWS DRUG DISCOVERY/19_7.txt
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vith
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19_7.txt
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A framework for RNA-based medicines, inspired by the Review on p421.
Cover design: S. Harris
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MAC_Bench/Nature/Story/NATURE REVIEWS DRUG DISCOVERY/23_7.txt
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vitg
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23_7.txt
|
The bispecific antibody landscape, inspired by the Review on p301.
Cover design: S. Harris
|
MAC_Bench/Nature/Story/NATURE REVIEWS DRUG DISCOVERY/23_9.txt
|
clip
|
23_9.txt
|
test
|
Trends in Chemistry
|
6_9
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Trends in Chemistry/6_9.png
|
C
|
In this special issue of Trends in Chemistry, we highlight the design and emerging catalytic applications of transition metals
and their complexes in organic and organometallic chemistry, including: C-C bond formation,
C-H functionalization, branch-selective olefin hydroarylation, carbon-dioxide methanation,
and chemo-catalytic cellulose conversion to ethanol. On pages 510–523 of this issue,
Rueping and colleagues discuss visible light-induced excited-state transition-metal
catalysis. In contrast to metal/photoredox dual catalysis which has garnered significant
attention as a bond-forming platform, excited-state transition-metal catalysis employs
a single metal complex as both the photo- and cross-coupling catalyst, offering potential
efficient and economic C-C bond formation.
|
MAC_Bench/Cell/Story/Trends in Chemistry/1_5.txt
|
ave_2
|
1_5.txt
|
In this special issue of Trends in Chemistry, we wrap up our inaugural content by continuing to address big questions in chemistry.
We introduce 14 new articles outlining key topics in chemistry including: lithium-metal
batteries; electrochemical water splitting; light hydrocarbon separations; glycosidic
bond hydroxylation; and two dimensional materials, just to name a few. The cover image
is a continuation of the Issue 1 cover but now with a collection of molecules, structures
and reactions primarily found within this issue.
|
MAC_Bench/Cell/Story/Trends in Chemistry/1_9.txt
|
ave_1
|
1_9.txt
|
The ability to image the dynamic processes, bonding forces and
conformational changes of biomacromolecules in a liquid environment in real time
would be vital to provide a deeper understanding of fundamental biological principles.
As an emerging method to reach this goal, liquid-phase electron microscopy (LP-EM)
can provide unique insights into complex structures such as proteins, lipids, and
nucleic
acids. In their Forum article, Huan Wang and colleagues highlight the progress made
in single-molecule LP-EM research so far, including use of deep learning methods,
and discuss future prospects for this technique to address unanswered questions in
biochemistry and biophysics. Image credit: GettyImages/Westend61
|
MAC_Bench/Cell/Story/Trends in Chemistry/6_9.txt
|
groundtruth
|
6_9.txt
|
In this special issue of Trends in Chemistry, we wrap up our inaugural content by continuing to address big questions in chemistry.
We introduce 14 new articles outlining key topics in chemistry including: lithium-metal
batteries; electrochemical water splitting; light hydrocarbon separations; glycosidic
bond hydroxylation; and two dimensional materials, just to name a few. The cover image
is a continuation of the Issue 1 cover but now with a collection of molecules, structures
and reactions primarily found within this issue.
|
MAC_Bench/Cell/Story/Trends in Chemistry/1_10.txt
|
clip
|
1_10.txt
|
train
|
Nature Neuroscience
|
27_12
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Neuroscience/27_12.png
|
B
|
Garfield and colleagues demonstrate that melanocortin-4 receptor (MC4R)-expressing neurons of the paraventricular nucleus of the hypothalamus (PVH) are required for the bidirectional control of feeding and that they induce satiety associated with an appetitive state. The cover depicts a stylized immunofluorescence image of MC4R-expressing neurons in the PVH (as demarked by an MC4R-t2a-Cre reporter line). It symbolizes both the PVH as the 'heart' of the hypothalamic feeding circuitry and the positive emotional valence of the MC4R-driven satiety. Cover design and concept by Michael J. Krashes and Alastair S. Garfield.789863
|
MAC_Bench/Nature/Story/Nature Neuroscience/18_7.txt
|
clip
|
18_7.txt
|
AgRP neurons encode circadian mealtimes
To maximize fitness, most animals adopt an optimal foraging strategy to procure the highest energy at the lowest cost. For example, nighttime is likely to be preferred by nocturnal animals owing to its relative safety from predators and the ease of food availability. In an environment with such periodic food availability, AgRP neurons are entrained by past successful feeding experiences and use this circadian information to promote foraging at similar time windows on subsequent days to maximize the chance of feeding.
See Sayar-Atasoy et al.
Image: Muhammed Ikbal Alp, InSpira. Cover Design: Marina Corral Spence
|
MAC_Bench/Nature/Story/Nature Neuroscience/27_12.txt
|
groundtruth
|
27_12.txt
|
This month's special issue of Nature Neuroscience features a series of reviews and opinionated pieces on the theme of spatial cognition.
|
MAC_Bench/Nature/Story/Nature Neuroscience/20_2.txt
|
vitg
|
20_2.txt
|
Animals engage in risky behaviors depending on potential gains and losses relative to current needs. For example, during starvation, they are more likely to forage for food where predators are prevalent and conspecifics can compete. Padilla et al. report a neural mechanism regulating these behaviors and describe a hypothalamic AgRP circuit controlling fear and aggression during nutritional deprivation.643734
|
MAC_Bench/Nature/Story/Nature Neuroscience/19_8.txt
|
ave_3
|
19_8.txt
|
train
|
Nature Reviews Endocrinology
|
20_5
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_5.png
|
B
|
Endocrine effects of immune checkpoint inhibitors, inspired by the Review on p389.
Cover design: Rachael Tremlett.
|
MAC_Bench/Nature/Story/Nature Reviews Endocrinology/17_6.txt
|
vith
|
17_6.txt
|
Targeting the incretin system in obesity and type 2 diabetes mellitus, inspired by the Review on p447.
Cover design: Jennie Vallis
|
MAC_Bench/Nature/Story/Nature Reviews Endocrinology/20_5.txt
|
groundtruth
|
20_5.txt
|
Mapping progress in cell replacement therapies for T1DM, inspired by the Review on p14.
Cover design: Edward Byrne
|
MAC_Bench/Nature/Story/Nature Reviews Endocrinology/21_2.txt
|
vitg
|
21_2.txt
|
Use of machine intelligence in endocrine cancer diagnostics, inspired by the Review on p81.
Cover design: Rachael Tremlett.
|
MAC_Bench/Nature/Story/Nature Reviews Endocrinology/18_11.txt
|
clip
|
18_11.txt
|
train
|
ACS Applied Bio Materials
|
2025_1
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2025_1.png
|
A
|
Chronic wounds are challenging due to infections and antibiotic resistance. This study develops hydrogels with gallium-based nanoalloys, combining bismuth and silver ions. These multi-metallic hydrogels exhibit antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa while being non-toxic and enhancing wound healing, providing an alternative to current antimicrobial treatments. The i
|
MAC_Bench/ACS/Story/ACS Applied Bio Materials/2025_1.txt
|
groundtruth
|
2025_1.txt
|
The cover image depicts the semiconducting oligomer amphiphiles (OPV-PEG)-based activatable nanoprobes for in vivo imaging of biothiols. OPV-PEG is composed of a hydrophobic semiconducting segment that serves as both the signal source and the sensing moiety for biothiols, and the hydrophilic poly(ethylene glycol) (PEG) side chains to provide the water-solubility. OPV-PEG can self-assemble with a near-infrared (NIR) photosensitizer to emit both NIR fluorescence and afterglow luminescence. In the presence of biothiols in living animals, the NIR fluorescence of this nanoprobe is turned on, but the afterglow signal remains the same, which permits precise tracking of the probe location while detecting biothiols.
|
MAC_Bench/ACS/Story/ACS Applied Bio Materials/2018_3.txt
|
clip
|
2018_3.txt
|
The cover image depicts a hydrogel for wound healing containing silver nanoparticles produced by gamma irradiation; these nanoparticles act as a shield protecting from any bacteria, while the hydrogel provides a moisture environment for the wound to recover. In one step using gamma irradiation, Ag+ are reduced leading to stabilization of nanosilver but also have hydrogel formation with terminal sterilization. Because of the potential effect of silver nanoparticles crosslinked in between the hydrogel, it leads to a fast wound healing, which makes it possible to identify its mechanisms with cell regeneration.
|
MAC_Bench/ACS/Story/ACS Applied Bio Materials/2018_1.txt
|
vitg
|
2018_1.txt
|
The cover image portrays an injectable neutrophilic attractant and antibacterial hydrogel applied to infected wounds. This hydrogel is made of κ-Carrageenan incorporated with octenidine dihydrochloride and chitosan-treated serum. Octenidine, an antiseptic agent, shows antibacterial activity by rupturing the bacterial membrane. Chitosan-treated serum induces migration of fibroblasts and neutrophils into the wounded area. Neutrophils further accelerate bacterial clearance. Fibroblasts facilitate tissue regeneration at the wounded site. This combinatorial effect helps in treating infectious wounds and facilitates the wound healing process.
|
MAC_Bench/ACS/Story/ACS Applied Bio Materials/2019_12.txt
|
vith
|
2019_12.txt
|
train
|
Trends in Chemistry
|
6_8
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Trends in Chemistry/6_8.png
|
C
|
Whilst many often look to past giants to find that spark of inspiration,
there is something exciting in looking to the future. For our two-part fifth anniversary
special issue, Trends in Chemistry is amplifying rising stars and emerging leaders
in
chemistry today. Our cover for part 1 showcases the 'great career race' for early-career
scientists today, with key milestones towards promotion and the many paths that can
be taken on the road to success. Each running at their own pace, the authors in this
issue are all aiming to innovate with an impact, solve real-world problems and become
inspiring leaders themselves. Artwork credit: Phillip Krzeminski
|
MAC_Bench/Cell/Story/Trends in Chemistry/6_7.txt
|
ave_1
|
6_7.txt
|
In this special issue of Trends in Chemistry, we wrap up our inaugural content by continuing to address big questions in chemistry.
We introduce 14 new articles outlining key topics in chemistry including: lithium-metal
batteries; electrochemical water splitting; light hydrocarbon separations; glycosidic
bond hydroxylation; and two dimensional materials, just to name a few. The cover image
is a continuation of the Issue 1 cover but now with a collection of molecules, structures
and reactions primarily found within this issue.
|
MAC_Bench/Cell/Story/Trends in Chemistry/1_10.txt
|
clip
|
1_10.txt
|
Whilst many often look to past giants to find that spark of inspiration,
there is something exciting in looking to the future. For our two-part fifth anniversary
special issue, Trends in Chemistry is amplifying rising stars and emerging leaders
in
chemistry today. Our cover for part 1 showcases the 'great career race' for early-career
scientists today, with key milestones towards promotion and the many paths that can
be taken on the road to success. Each running at their own pace, the authors in this
issue are all aiming to innovate with an impact, solve real-world problems and become
inspiring leaders themselves. Artwork credit: Phillip Krzeminski
|
MAC_Bench/Cell/Story/Trends in Chemistry/6_8.txt
|
groundtruth
|
6_8.txt
|
Whilst many often look to past giants to find that spark of inspiration,
there is something exciting in looking to the future. For our two-part fifth anniversary
special issue, Trends in Chemistry is amplifying rising stars and emerging leaders
in
chemistry today. Our cover for Part II continues on from Part I, highlighting some
of the
milestones and many paths taken on the 'great career race' for early-career scientists
today. Each running at their own pace, the authors in this special issue are all aiming
to innovate with an impact, solve real-world problems and become inspiring leaders
themselves. Artwork credit: Phillip Krzeminski
|
MAC_Bench/Cell/Story/Trends in Chemistry/6_6.txt
|
vith
|
6_6.txt
|
train
|
ACS Sustainable Chemistry & Engineering
|
2025_2
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2025_2.png
|
A
|
Self-assembly of cellulose nanocrystals (CNCs) synthesized from rice straw yields transparent films with distinct structural colors. Amine modification of CNCs significantly improves the electron mobility and current–voltage characteristics. The transreflective property and photoresponsivity of
|
MAC_Bench/ACS/Story/ACS Sustainable Chemistry & Engineering/2025_2.txt
|
groundtruth
|
2025_2.txt
|
The cover art illustrates the innovative method of synthesizing spherical lignin-based 3D porous carbons (LSPCs). These ecofriendly spheres depict high surface areas and customizable micro/mesopores. With their impressive performance in supercapacitors and sodium-ion batteries, these materials significantly advance in creating ecofriendly energy storage solutions.
|
MAC_Bench/ACS/Story/ACS Sustainable Chemistry & Engineering/2024_47.txt
|
vith
|
2024_47.txt
|
Graphics from this issue of ACS Sustainable Chem. Eng.
|
MAC_Bench/ACS/Story/ACS Sustainable Chemistry & Engineering/2017_12.txt
|
vitg
|
2017_12.txt
|
Lower right: Catalytic hydrogenation-esterification, which yields products favorable for subsequent upgrading, will benefit the high-grade utilization of sustainable biomass energy. (See J. Chen, Q. Cai, L. Lu, F. Leng, and S. Wang; DOI: 10.1021/acssuschemeng.6b02366.)
|
MAC_Bench/ACS/Story/ACS Sustainable Chemistry & Engineering/2017_9.txt
|
clip
|
2017_9.txt
|
test
|
ACS Applied Polymer Materials
|
2024_4
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_4.png
|
A
|
This cover illustration shows superior thermal conducting properties of newly developed liquid crystal (LC) materials derived from improved molecular orientation by polymerization. LC epoxy resins exhibit high thermal conductivity based on mesogen networks oriented by intermolecular interactions with excellent potential as electronic materials.
|
MAC_Bench/ACS/Story/ACS Applied Polymer Materials/2024_4.txt
|
groundtruth
|
2024_4.txt
|
This cover art illustrates the antibacterial schematic diagram of the versatile gelatin-PAAm-Ag NPs double network hydrogel coating on both the outer and lumen (inner) surfaces of disposable silicified latex urinary catheters (UCs). This study provides valuable insights and strategies for the development of novel antibacterial hydrogel coatings for UCs and other biomedical devices aimed at reducing catheter-associated urinary tract infections.
|
MAC_Bench/ACS/Story/ACS Applied Polymer Materials/2025_2.txt
|
ave_1
|
2025_2.txt
|
A newly synthesized azobenzene-based monoacrylate molecule (AM) is used to develop multifunctional liquid crystal polymer networks (LCPNs) with photothermal effect. The multifunctionality of the strategically optimized and manufactured AM LCPN was demonstrated through the identification of shape memory, orientation, and self-healing properties.
|
MAC_Bench/ACS/Story/ACS Applied Polymer Materials/2023_11.txt
|
vitg
|
2023_11.txt
|
The cover art depicts a biomimetic 3D-printed armored structure inspired by armadillo shells for durable superhydrophobic surfaces. It showcases hexagonal patterns protecting inner hydrophobic nanoparticles, repelling water droplets. The design illustrates the approach of integrating 3D printing with nanomaterial surface treatments to create wear-resistant, water-repellent coatings for harsh environments.
|
MAC_Bench/ACS/Story/ACS Applied Polymer Materials/2024_3.txt
|
clip
|
2024_3.txt
|
test
|
Journal of the American Chemical Society
|
2024_17
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_17.png
|
A
|
A long polypeptide chain, exceeding 700 amino acids, is propelled through a protein nanopore. Phosphorylation-specific binders, when bound to the translocating peptide, create unique signatures that enable the detection of phosphoserine sites over 250 residues apart within a single chain. [Cover by
|
MAC_Bench/ACS/Story/Journal of the American Chemical Society/2024_17.txt
|
groundtruth
|
2024_17.txt
|
Sandwich-type phthalocyanine (Pc) complexes have been limited to the dimer and trimer species in the past. This cover shows that the reaction of a double-decker Pc with a cadmium salt yields a discrete quadruple-decker Pc complex, which is the first buildup since the synthesis of a triple-decker Pc complex in 1986. See Fukuda and co-workers, p 6278. View the article.
|
MAC_Bench/ACS/Story/Journal of the American Chemical Society/2010_34.txt
|
clip
|
2010_34.txt
|
A liquid–solid hybrid catalyst derived from Pickering emulsions has been successfully developed for continuous-flow reactions, which provides a new way for bridging the conceptual and technical gaps between homogeneous, heterogeneous and biological catalysis. See Yang and co-workers, DOI: 10.1021/jacs.8b11860. View the article.
|
MAC_Bench/ACS/Story/Journal of the American Chemical Society/2019_39.txt
|
vitg
|
2019_39.txt
|
The respiratory Complex I is a redox-driven proton pump powering aerobic life. The cover shows an artistic representation of how catalysis of quinone (glowing purple molecule) in Complex I drives long-range conformational changes that initiate proton pumping across a biological membrane. View the article.
|
MAC_Bench/ACS/Story/Journal of the American Chemical Society/2023_21.txt
|
vith
|
2023_21.txt
|
train
|
Acta Pharmacologica Sinica
|
45_5
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_5.png
|
D
|
Cover Credit: Mechanisms of Takeda G protein-coupled receptor-5 (TGR5) agonist on inhibiting intestinal epithelial cell apoptosis and ameliorating ulcerative colitis. Activation of TGR5 by OM8 enhanced cAMP/PKA signaling, which led to upregulation of c-FLIP expression, and subsequently suppressed JNK phosphorylation, thereby antagonizing TNF-α induced intestinal epithelial cell apoptosis.
|
MAC_Bench/Nature/Story/Acta Pharmacologica Sinica/44_5.txt
|
vitg
|
44_5.txt
|
Cover Credit: In this cover article, Zhou et al. constructed a novel mechanistic quantitative systems pharmacology model describing the underlying pathophysiological processes of HER2+BC, from ligand-receptor binding to downstream signaling and finally to tumor growth, while incorporating the distinct modalities and mechanisms of various state-of-the-art therapeutics. A large variety of in vitro and in vivo experimental data was used during model calibration and validation, achieving a quantitative and accurate description of cellular signaling, time-response, dose-response, and tumor growth kinetics. In a high-throughput manner, this multiscale QSP model platform enabled researchers to probe into the efficacy of different therapeutic strategies at the preclinical level, generate new hypothesis regarding best treatment combinations to overcome resistance, and suggested important directions for future translational drug research and model-informed drug development. Doi:10.1038/s41401-024-01232-9. See the article in pages 1287–1304
|
MAC_Bench/Nature/Story/Acta Pharmacologica Sinica/45_7.txt
|
ave_2
|
45_7.txt
|
Cover Credit: DZ2002, a reversible inhibitor of type III S-adenosyl-L-homocysteine hydrolase, attenuates TNF-α-induced NF-κB signaling by suppressing the degradation and phosphorylation of IκB, along with NF-κB p65 phosphorylation and nuclear translocation. Additionally, DZ2002 inhibits the activation of molecules in the STAT3-PI3K-Akt pathway, suppressing the secretion of inflammatory cytokines and pro-angiogenic factors. These findings strongly support DZ2002's promising therapeutic potential for dry eye disease (DED).
|
MAC_Bench/Nature/Story/Acta Pharmacologica Sinica/45_12.txt
|
clip
|
45_12.txt
|
Cover Credit: Reduction-activatable PROTAC prodrug nanoparticles for tumor-targeted protein degradation and anticancer therapy. The reduction-activatable PROTAC prodrug nanoparticles (NPs) were engineered by self-assembly of the PROTAC-conjugated amphiphilic diblock copolymer and further functionalized with a CRGDK ligand. The resulting PROTAC prodrug NPs can specifically target tumor cells and be efficiently internalized by recognizing neuropilin-1 (NRP-1), which is overexpressed on the surface of tumor cells. Remarkably, the PROTAC prodrug NPs efficiently degraded the protein targets BRD4 and CDK9 for inhibiting tumor growth in an mouse model of MDA-MB-231 triple-negative breast cancer. More importantly, the PROTAC prodrug NP can serve as a platform for co-delivering chemotherapeutic agents (e.g., doxorubicin, DOX) to perform combinatory cancer therapy. (Doi: 10.1038/s41401-024-01266-z). See the article in pages 1740–1751.
|
MAC_Bench/Nature/Story/Acta Pharmacologica Sinica/45_5.txt
|
groundtruth
|
45_5.txt
|
train
|
Journal of Chemical Theory and Computation
|
2024_10
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_10.png
|
D
|
A computational strategy is presented to improve the accuracy of local coupled cluster methods for systems containing first row transition metals. Dynamic correlation-induced orbital relaxation effects were identified as the main error source in local coupled cluster calculations. The cover art features a transition metal complex in the benchmark set.
|
MAC_Bench/ACS/Story/Journal of Chemical Theory and Computation/2023_18.txt
|
clip
|
2023_18.txt
|
The effects of protein scaffolding on enzymatic catalysis are evident in the active site electron charge density. Geometric constraints on charge density isosurfaces mean that charge redistribution is facilitated in some regions and hindered in others. The most mobile regions of charge density coincide with bond bundles, which provide a sensitive probe for charge density analysis. The cover shows analogous bond bundles and critical point characteristic angles (double cones) in acetone and in the ketosteroid isomerase active side.
|
MAC_Bench/ACS/Story/Journal of Chemical Theory and Computation/2023_22.txt
|
ave_1
|
2023_22.txt
|
An artistic interpretation of the charge pushback induced by water at the aqueous Pt(111) interface. This rearrangement of charge density is responsible for most of the work function change produced by adsorbed water for metallic surfaces. J. Chem. Theory Comput. 2020, 16, 2703–2715.
|
MAC_Bench/ACS/Story/Journal of Chemical Theory and Computation/2020_8.txt
|
vith
|
2020_8.txt
|
The new open source QupKake model from Abarbanel and Hutchison combines fast semiempirical quantum chemical data with machine learning methods to predict the local aqueous pKa of atomic sites in organic molecules for both protonation and deprotonation.
|
MAC_Bench/ACS/Story/Journal of Chemical Theory and Computation/2024_10.txt
|
groundtruth
|
2024_10.txt
|
train
|
Nature Cell Biology
|
26_10
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Cell Biology/26_10.png
|
A
|
ER-phagy during neurogenesis
Quantitative proteomics analyses show the importance of selective autophagy in endoplasmic reticulum (ER) remodelling across neuronal subcompartments and decode the substrate selectivity of ER-phagy receptors during in vitro neurogenesis.
See Hoyer et al. and News & Views by Molinari
Image: Cristina Capitanio, Max Planck Institute of Biochemistry, Martinsried, Germany. Cover Design: Lauren Heslop
|
MAC_Bench/Nature/Story/Nature Cell Biology/26_10.txt
|
groundtruth
|
26_10.txt
|
Focus on cell death
The cover shows 3-colour live imaging in vivo demonstrating a role for ferroptosis-like cell death in triggering macrophage recruitment but delaying the resolution of inflammation during wounding in Drosophila. See Focus for more content. Focus
See Davidson et al.
Image: Andrew J. Davidson, University of Glasgow. Cover design: Lauren Heslop
|
MAC_Bench/Nature/Story/Nature Cell Biology/26_4.txt
|
vith
|
26_4.txt
|
Stem cells
Stabilising naïve pluripotency
See Lynch et al..
Image: Photo courtesy of Cian J. Lynch, Institute for Research in Biomedicine (IRB), Barcelona, Spain. Cover Design: Lauren Heslop.
|
MAC_Bench/Nature/Story/Nature Cell Biology/22_3.txt
|
vitg
|
22_3.txt
|
This issue of Nature Cell Biology includes a series of six specially commissioned articles that collectively highlight how misfunctioning developmental pathways can cause disease. The articles are freely accessible until February 2008 at www.nature.com/ncb/webfocus/developmentdisease
|
MAC_Bench/Nature/Story/Nature Cell Biology/9_4.txt
|
clip
|
9_4.txt
|
train
|
iScience
|
27_4
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/iScience/27_4.png
|
A
|
On the Cover: The cover image represents the profound connection between the brain
and the gut microbiome, central to the study by Novielli et al. on the personalized identification of autism-related bacteria using eXplainable Artificial
Intelligence (XAI). The left half of the image, depicting the brain with illuminated
neural circuits, symbolizes the application of advanced AI techniques. The right half,
showcasing the gut with various microorganisms, highlights the diversity of the microbiome
and its potential link to autism. This visual metaphor encapsulates our study's dual
focus: utilizing AI to identify specific gut bacteria associated with autism and enhancing
our understanding of the gut-brain axis in neurodevelopmental disorders. Image credit:
Sabina Tangaro.
|
MAC_Bench/Cell/Story/iScience/27_4.txt
|
groundtruth
|
27_4.txt
|
On the cover: The image represents an oniric virtual reality environment that shows
how a physical activity, like cycling, improves spatial memory and could benefit both
fitness and cognition. Image credit: Nadia de la Cruz.
|
MAC_Bench/Cell/Story/iScience/26_9.txt
|
vitg
|
26_9.txt
|
On the cover: The parts of the cover image represent the following: (1) bluish background:
the atmospheric lack of oxygen in the universe, illustrating hypoxia; (2) two cells
compressing the brain: ischemia during asphyxia in the neonatal/perinatal brain; (3)
pink cell (left): infiltrating macrophages; (4) blue cell (right): microglia; (5)
playfully moving ribbon: change, symbolizing the causes and the complexity of the
injury and post-ischemic inflammatory cascades, but also future solutions; (6) dots
in the ribbon: the genes, transcription factors, and molecules involved in the signaling,
resulting in matrisome and metabolic dynamics in the two cell types; (7) the background
space: the extracellular matrix, a fluid/medium mediating the crosstalk between the
different actors; and (8) the pink and blue background dots: signaling molecules from
macrophages and microglia or sex differences. See Di Martino et al. Illustrator: Mattias Karlen.
|
MAC_Bench/Cell/Story/iScience/27_8.txt
|
vith
|
27_8.txt
|
On the Cover: The image depicts a Tic-tac-toe match where the players use an intriguing
set of pens named “Axonpens.” The player using the “SOX2 wild-type” Axonpen wins,
drawing a straight line connecting the eye to the brain, while the player using the
“SOX2 knock-out” Axonpen loses. This is a funny representation of the main findings
of Mercurio et al. (volume 15, 2019). The development of the visual system involves
the formation of neuronal projections connecting the retina to the thalamus and the
thalamus to the visual cerebral cortex. Deletion of Sox2 in thalamic neurons results
in abnormal development of retino-thalamic and thalamo-cortical projections and secondary
defects in cortical patterning. Image by Lorenzo Gesuita.
|
MAC_Bench/Cell/Story/iScience/16_1.txt
|
clip
|
16_1.txt
|
test
|
Precision Chemistry
|
2024_4
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/Precision Chemistry/2024_4.png
|
B
|
This cover art for the Special Issue “Precision Chemistry for Two-Dimensional Materials” was designed by Xiangfeng Duan of the University of California, Los Angeles and coworkers. It illustrates CuxBi2Se3 nanoplates with systematically tunable Cu doping concentrations, doping sites, and electronic properties as a potential material for future electronics.
|
MAC_Bench/ACS/Story/Precision Chemistry/2024_5.txt
|
clip
|
2024_5.txt
|
Constructing charge-transfer channels in ZnIn2S4 by doping Ru single atoms (SAs), where the photogenerated electrons migrate from Ru SAs to S sites, as a result of enhanced separation of electron-hole pairs, leading to the ultrahigh H2 productivity under visible light irradiation in the absence of sacrificial agents.
|
MAC_Bench/ACS/Story/Precision Chemistry/2024_4.txt
|
groundtruth
|
2024_4.txt
|
The cover for the Special Issues "Precision Chemistry for Two-Dimensional Materials (Part I)" illustrates the precise growth of non-centrosymmetric two-dimensional single crystals. Humanoid models represent atoms A and B in the lattice, which are guided by the parallel steps. Cover art concept by Guoliang Cui and Xiaozhi Xu.
|
MAC_Bench/ACS/Story/Precision Chemistry/2024_6.txt
|
ave_2
|
2024_6.txt
|
Selective catalysis on metal nanoparticles represents a grand challenge in chemical synthesis. This cover art illustrates how visible-light illumination alters the electronic structures of surface atoms in platinum nanoparticles, promoting the selective synthesis of phenylhydroxylamine from the hydrogenation of nitrobenzene. In contrast, the reaction in the dark primarily produces aniline.
|
MAC_Bench/ACS/Story/Precision Chemistry/2023_7.txt
|
vith
|
2023_7.txt
|
train
|
NATURE GENETICS
|
56_12
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/NATURE GENETICS/56_12.png
|
C
|
Engineering crop polyploid genomes
Generation of clonal gametes in tomato enables polyploid genome design through controlled combination of pre-defined genome haplotypes.
See Wang et al.
Image: Rainer Franzen, Yazhong Wang and Rob Kesseler. Cover design: Tulsi Voralia
|
MAC_Bench/Nature/Story/NATURE GENETICS/56_7.txt
|
clip
|
56_7.txt
|
Coffea arabica diversification history
Genome assemblies of allotetraploid Coffea arabica and representatives of its diploid progenitors provide insights into diversification history.
See Salojärvi et al.
Image: Amanda van der Sijs/500px/Getty. Cover design: Tulsi Voralia
|
MAC_Bench/Nature/Story/NATURE GENETICS/56_9.txt
|
ave_1
|
56_9.txt
|
Banana genome evolution
Genome assemblies of triploid Cavendish and Gros Michel bananas reveal the origins, disease resistance and fruit-ripening mechanisms of the banana cultivars.
See Li et al.
Image: Aleksandr Zubkov/Moment/Getty. Cover design: Tulsi Voralia.
|
MAC_Bench/Nature/Story/NATURE GENETICS/56_12.txt
|
groundtruth
|
56_12.txt
|
Mendel and memories
In celebration of the 200th anniversary of Gregor Mendel’s birth and the 30th anniversary of the launch of Nature Genetics, we look both forwards and backwards at how far the genetics field has come. This cover image is inspired by the cover of the first issue of Nature Genetics in 1992.
Image and Cover Design: Valentina Monaco.
|
MAC_Bench/Nature/Story/NATURE GENETICS/54_6.txt
|
vitg
|
54_6.txt
|
train
|
Nature Cancer
|
6_1
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Cancer/6_1.png
|
C
|
One year of Nature Cancer
This month we celebrate one year of Nature Cancer with a specially curated collection of Nature Cancer articles and a new type of commissioned Clinical Outlook articles.
See Editorial and the One Year of Nature Cancer collection
Image: Ryan Carter / Alamy Stock Photo. Cover Design: Lauren Heslop.
|
MAC_Bench/Nature/Story/Nature Cancer/2_12.txt
|
clip
|
2_12.txt
|
2023 in Review
This month we present a dedicated Focus issue, ‘2023 in Review’, that includes news, analyses and comments on the advances and challenges of the past year, together with highlights from the primary research articles published in Nature Cancer and elsewhere over the past 12 months.
See our December Editorial and associated Focus content.
Image: ICP-Tech / Incamerastock / Alamy Stock Photo. Cover design: Allen Beattie
|
MAC_Bench/Nature/Story/Nature Cancer/4_1.txt
|
ave_3
|
4_1.txt
|
Five years of Nature Cancer
We mark Nature Cancer’s fifth anniversary with a Series of specially commissioned Reviews and opinion pieces on key developments in cancer research and oncology, together with a collection of primary research articles published in Nature Cancer over the past 5 years.
See our January Editorial
Image: Lukas Jonaitis / Alamy Stock Photo. Cover design: Allen Beattie
|
MAC_Bench/Nature/Story/Nature Cancer/6_1.txt
|
groundtruth
|
6_1.txt
|
2024 in Review
This month we present a dedicated issue, Focus on 2024 in Review, that includes news, analysis and comment pieces on the most exciting advances and biggest challenges of the past year, together with a selection of the primary research articles published in Nature Cancer and elsewhere over the past 12 months.
See our December Editorial and associated Focus content.
Image: Ernie Janes / Alamy Stock Photo. Cover design: Allen Beattie
|
MAC_Bench/Nature/Story/Nature Cancer/5_1.txt
|
ave_2
|
5_1.txt
|
test
|
Cell Chemical Biology
|
31_6
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Cell Chemical Biology/31_6.png
|
C
|
On the cover: After more than 20 years supporting the community of scientists dedicated
to research done at the interface of chemistry and biology, we bid farewell to Chemistry & Biology and introduce you to Cell Chemical Biology. We are excited about the new title that clearly reflects our commitment to chemical
biology and our alignment with the Cell Press family of journals. We are even more
excited about the exceptional science that we will continue to publish, and this special
issue highlights some of the areas in which chemical biology has been pushing the
limits and reaching for the blue skies.
|
MAC_Bench/Cell/Story/Cell Chemical Biology/23_12.txt
|
vith
|
23_12.txt
|
On the cover: Join us in celebrating the 30th anniversary of Cell Chemical Biology with this special issue. The imagery reflects the multidisciplinary nature of the
journal, spanning all areas of biological and biomedical sciences from academia to
industry, collectively forming the vibrant field of chemical biology. Dive into the
editorial to explore the journal's rich history, ongoing achievements, and future directions.
Cover art by Julie Sung.
|
MAC_Bench/Cell/Story/Cell Chemical Biology/31_4.txt
|
ave_1
|
31_4.txt
|
On the cover: Dual targeting of proteins (orange and blue) on the same cell surface
via bispecific antibodies (pink beige) holds great therapeutic promise with novel
modes of action that are rapidly advancing towards the clinic. Oslund et al. review the therapeutic impact of cis-targeting bispecific antibodies (pink beige)
in the clinic and their emerging applications and highlight features for enhancing
cis-targeting bispecific therapeutic development. Cover art created by Yi Zheng (yizhengillustration).
|
MAC_Bench/Cell/Story/Cell Chemical Biology/31_6.txt
|
groundtruth
|
31_6.txt
|
On the cover: Join us in celebrating the 30th anniversary of Cell Chemical Biology with this special issue. The imagery reflects the multidisciplinary nature of the
journal, spanning all areas of biological and biomedical sciences from academia to
industry, collectively forming the vibrant field of chemical biology. Dive into the
editorial to explore the journal's rich history, ongoing achievements, and future directions.
Cover art by Julie Sung.
|
MAC_Bench/Cell/Story/Cell Chemical Biology/31_5.txt
|
clip
|
31_5.txt
|
test
|
Accounts of Materials Research
|
2024_7
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_7.png
|
D
|
Metal–organic frameworks featuring well-defined active sites enable efficient activation and conversion of methane, promoting sustainable production of value-added chemicals.
|
MAC_Bench/ACS/Story/Accounts of Materials Research/2025_1.txt
|
ave_1
|
2025_1.txt
|
Integrating domain knowledge into artificial intelligence, this Account signifies a transformative shift in catalytic materials discovery toward a sustainable future. Cover designed by Tianyou Mou with help from Xue Han.
|
MAC_Bench/ACS/Story/Accounts of Materials Research/2024_12.txt
|
clip
|
2024_12.txt
|
This Account highlights our ongoing research on the construction of porous organic polymer (POP)-based catalysts, discussing the design strategies and principles involved with the aim of underscoring the unique features of POPs fabricated via solvothermal free-radical polymerization of vinylated functionalities for the development of genuinely competitive artificial enzymes.
|
MAC_Bench/ACS/Story/Accounts of Materials Research/2022_6.txt
|
vitg
|
2022_6.txt
|
CO2 electrolysis driven by sustainable energy resources is an attractive way to close the carbon cycle and achieve carbon neutrality. This Account highlights recent advances in cathode materials design for CO2 electrolysis from room to elevated temperatures, with a focus on various strategies.
|
MAC_Bench/ACS/Story/Accounts of Materials Research/2024_7.txt
|
groundtruth
|
2024_7.txt
|
train
|
Science Robotics
|
9_89
|
Which of the following options best describe the cover image?
|
MAC_Bench/Science/Cover/Science Robotics/9_89.png
|
A
|
ONLINE COVER Special Issue on Legged Robots. Developing legged robots capable of complex motor skills is a major challenge for roboticists. Haarnoja et al. used deep reinforcement learning to train miniature humanoid robots, Robotis OP3, to play a game of one-versus-one soccer. The robots were capable of exhibiting not only agile movements, such as walking, kicking the ball, and rapid recovery from falls, but also emergent behaviors to adapt to the game scenario, such as subtle defensive moves and dynamic footwork in response to the opponent. This month’s cover is an image of the miniature humanoid robot kicking a ball. Credit: Google DeepMind
|
MAC_Bench/Science/Story/Science Robotics/9_89.txt
|
groundtruth
|
9_89.txt
|
ONLINE COVER A Model of Oneself. Robots, like humans and animals, require self-models to be able to anticipate and plan future actions. Chen et al. developed a method that enables a robot arm to model its morphology and kinematics using an approach based on query-driven visual self-modeling. This month’s cover is a multiple-exposure image of a self-modeled robot arm touching a small red sphere while avoiding a large red cube. Credit: Columbia Engineering
|
MAC_Bench/Science/Story/Science Robotics/7_68.txt
|
ave_2
|
7_68.txt
|
ONLINE COVER Special Issue on Autonomy and AI in Robotics. A team of legged robots can efficiently explore unstructured terrains with task-level autonomy. Arm et al. report on a robot team comprising a “scout” that can identify potential scientific targets in an environment, a “hybrid” that collects data from the targets, and a “scientist” that performs in-depth scientific analysis of the targets. The robot team could efficiently map terrain mimicking planetary environments, identify resource-enriched areas, and scientifically analyze targets of interest. This month’s cover is an image of a team of legged robots exploring a field of boulders. Credit: Arm et alMAC_Bench/Science Robotics
|
MAC_Bench/Science/Story/Science Robotics/8_80.txt
|
clip
|
8_80.txt
|
ONLINE COVER Opening Doors. Robot swarms are designed to achieve complex global behaviors through simple local interactions between robots with very rudimentary sensing and locomotive abilities. Boudet et al. demonstrate that a swarm of primitive, centimeter-scale, vibrating robots bound by a deformable metal scaffold can give rise to directional motion. The mechanically coupled motion of the simple robots and the scaffold enable nontrivial space exploration in specifically configured environments. This month's cover is a photograph of a swarm of simple robots in a flexible membrane passing through a door. [CREDIT: HAMID KELLAY, JEAN FRANÇOIS BOUDET, BENJAMIN GORIN/UNIVERSITY OFBORDEAUX]
|
MAC_Bench/Science/Story/Science Robotics/6_56.txt
|
vitg
|
6_56.txt
|
train
|
Cell Chemical Biology
|
32_1
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Cell Chemical Biology/32_1.png
|
C
|
On the cover: Climbing a mountain with all its nooks and crannies (energy wells) is
an apt metaphor for the selection of functional antibodies. One starts with an enormous
collection of candidates from which only a few are selected (reach the mountain top).
In Xie et al. (pp. 274–283), only two antibodies out of approximately 108 were selected
that could prevent cell death. The antibodies functioned by binding to the viral protease
and either inhibited its catalytic function or prevented its entry into the viral
maturation process.
|
MAC_Bench/Cell/Story/Cell Chemical Biology/21_11.txt
|
clip
|
21_11.txt
|
On the cover: Join us in celebrating the 30th anniversary of Cell Chemical Biology with this special issue. The imagery reflects the multidisciplinary nature of the
journal, spanning all areas of biological and biomedical sciences from academia to
industry, collectively forming the vibrant field of chemical biology. Dive into the
editorial to explore the journal's rich history, ongoing achievements, and future directions.
Cover art by Julie Sung.
|
MAC_Bench/Cell/Story/Cell Chemical Biology/31_5.txt
|
vitg
|
31_5.txt
|
On the cover: Sharma et al. describe the chemical interplay between the gut microbiota and host circadian physiology
via the epigenetic circuit. Members of the gut microbiota fine-tune host functions
(yellow bacterium and pink intestinal epithelial cells), synthesize host-sensed metabolites
(orange bacterium and orange-yellow receptor), interact with intestinal epithelium
and immune cells (blue, dark green, and light green bacterium and light-orange immune
cell), and can harm the host (purple bacterium). Cover art by Samskrathi Aravinda
Sharma.
|
MAC_Bench/Cell/Story/Cell Chemical Biology/32_1.txt
|
groundtruth
|
32_1.txt
|
On the cover: After more than 20 years supporting the community of scientists dedicated
to research done at the interface of chemistry and biology, we bid farewell to Chemistry & Biology and introduce you to Cell Chemical Biology. We are excited about the new title that clearly reflects our commitment to chemical
biology and our alignment with the Cell Press family of journals. We are even more
excited about the exceptional science that we will continue to publish, and this special
issue highlights some of the areas in which chemical biology has been pushing the
limits and reaching for the blue skies.
|
MAC_Bench/Cell/Story/Cell Chemical Biology/23_12.txt
|
vith
|
23_12.txt
|
train
|
Nature Protocols
|
19_10
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Protocols/19_10.png
|
A
|
Studying human brain vascular cells with single-cell transcriptomics and organoids
Human brain vascular cells, including endothelial and mural cells, can be purified with FACS and used in many downstream applications, including cell culture, transcriptomics and organoid transplants. This image shows vascular cells labeled with GFP and transplanted on top of induced pluripotent stem cell (iPSC)-derived cortical organoids. See Crouch et al. p603
Image : Elizabeth Crouch, University of California San Francisco. Cover design: S. Whitham
|
MAC_Bench/Nature/Story/Nature Protocols/19_10.txt
|
groundtruth
|
19_10.txt
|
Nervous heart.
The cover shows 3D FLASH immunofluorescence staining of nerves (tyrosine hydroxylase) and extracellular matrix (collagen IV) of a whole murine heart.
See Messal et al.
Image: Axel Behrens. Cover design: Tulsi Voralia.
|
MAC_Bench/Nature/Story/Nature Protocols/16_12.txt
|
ave_1
|
16_12.txt
|
The cytoarchitecture of an ALI-CO
The cover shows an air–liquid interface cerebral organoid (ALI-CO) expressing foci of a membrane-targeted GFP construct (cyan) and stained for the pan-neuronal cytoskeletal marker TUBB3 (red), the axonal marker SMI312 (green) and the neuronal transcription factor NeuroD2 (blue). Thick axon bundles project around the edges and toward the center of the organoid, outlining lobules containing neuronal nuclei and axons in a radially ordered lattice.
See Giandomenico et al.
Image: Stefano L. Giandomenico. Cover design: Tulsi Voralia.
|
MAC_Bench/Nature/Story/Nature Protocols/16_11.txt
|
ave_2
|
16_11.txt
|
Human neurons in culture
Image of human striatal organoids that are derived from pluripotent stem cells in vitro and can be integrated with cortical cells to form cortico-striatal assembloids.
See Miura et al.
Image: Sergiu P. Pașca, Stanford University. Cover design: Tulsi Voralia.
|
MAC_Bench/Nature/Story/Nature Protocols/17_12.txt
|
clip
|
17_12.txt
|
train
|
Immunity
|
57_9
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Immunity/57_9.png
|
C
|
On the cover: 2019 marks the 25th anniversary of Immunity. The cover for this anniversary issue was designed to celebrate our authors, reviewers,
and readers and was created with photos submitted by immunology labs from around the
world (download the high-resolution image here). These photos, along with information about each lab, are compiled in a companion
website (https://www.cell.com/immunity/community) that we hope will serve as a resource to foster connections within the immunology
community. We thank all of the labs that participated in this effort—it has been fun!
In this issue, we also present to you fourteen commissioned reviews on the theme of
cytokines. These articles highlight the progress made in both the understanding of
these fundamental effectors of immunity and the translation of these insights into
the clinic. Cover design by Kavitha Scranton.
|
MAC_Bench/Cell/Story/Immunity/50_3.txt
|
clip
|
50_3.txt
|
On the cover: In this issue, Bosteels, Neyt, et al. (1039–1056) report the identification
of a subset of conventional dendritic cells (cDCs), which they term inflammatory cDC2s,
that combines characteristics of monocytes, macrophages, and cDCs to induce the optimal
immunity in the context of a viral respiratory infection. The alveolar-capillary interface
characterized by a delicate balance between adequate oxygenation (air bubbles) and
inflammation is depicted as a seabed. Different cDCs (octopus)—cDC1s, cDC2s, and inflammatory
cDC2s—patrol this seabed, sampling antigen and integrating the nature of threats encountered
to initiate appropriate immune responses. Cover design by Jonas Bossuyt and Cedric
Bosteels.
|
MAC_Bench/Cell/Story/Immunity/52_1.txt
|
ave_2
|
52_1.txt
|
On the cover: 2024 marks the 30th anniversary of Immunity! To celebrate this milestone with the immunology community, we hosted an open call
for cover submissions for our special anniversary issue and are grateful to have received
beautiful and creative submissions from across the globe! The winning design featured
on the cover of this anniversary issue was designed by Yun Hsuan Elena Lin, a PhD
candidate in the laboratory of Dr. John Chang at the University of Californa, San
Diego. In her illustration, immune cells are depicted as flowers flourishing from
vases in the shape of the number 30. The stalks of the flowers are comprised of DNA,
RNA, mitochondria, antibodies, blood vessels, lymphatics, neuronal and glial cells,
microbes, and more, highlighting advances in immunology research over the past decades.
Model organisms populate the image as well, recognizing their key contributions in
driving substantial advances in human immunology. The bouquet captures the diversity
of immunological research published by Immunity, painted over a backdrop of dawn that symbolizes the exciting discoveries to come. In this issue, we present a collection of review and perspective articles on innate
immunity with a focus on pattern recognition. Rather than recognizing unique aspects
of a pathogen, the innate immune system uses families of receptors that recognize
shared features of potential threats to the host. Likewise, sensing of endogenous
molecular patterns enables maintenance of health. Throughout this collection of articles,
we explore the latest understanding of how the innate immune system evolved to ensure
that the body responds appropriately to the myriad of microbes in the environment
while maintaining regulation of homeostatic functions, how these mechanisms can go
awry in disease, and the prospects for harnessing these insights into the development
of new therapies.
|
MAC_Bench/Cell/Story/Immunity/57_9.txt
|
groundtruth
|
57_9.txt
|
On the cover: This year marks the twentieth anniversary of the JAK-STAT signaling
pathway—a signaling axis fundamental to a broad range of immune responses including
cytokine and interferon signaling. In this issue of Immunity, we celebrate this anniversary with a special collection of review articles. Stark
and Darnell (pages 503–514) provide a personal account of the discovery of the pathway
and summarize recent insights into the molecular mechanisms of its regulation and
function. Casanova and colleagues (pages 515–528) cover inborn errors in human genes
encoding JAKs and STATs and discuss how these mutations have illuminated the functional
importance of this signaling pathway in infection and immunity. Mutations in JAKs
have also been found certain cancers of the immune system, and Staudt and colleagues
(pages 529–541) highlight our current knowledge on the prevalence of these lesions
in leukemia and lymphoma. Finally, O'Shea and Plenge (pages 542–550) review immunoregulatory
roles of the JAK-STAT pathway, insights gained from genomewide analyses into possible
links between this pathway and autoimmunity, and recent targeted therapeutic approaches
designed to inhibit JAK function. Clearly, there is much more to be discovered about
the role of the JAK-STAT pathway in the immune system, and the next twenty years is
likely to reveal new insights into this important pathway as well as therapeutic means
of regulating its function. Cover art by Alan Hoofring of the NIH Medical Arts Design
section.
|
MAC_Bench/Cell/Story/Immunity/36_3.txt
|
ave_3
|
36_3.txt
|
train
|
Nature Reviews Cardiology
|
22_2
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Reviews Cardiology/22_2.png
|
C
|
DEI in Cardiology, inspired by the Roadmap on p765.
Cover design: Vicky Summersby.
|
MAC_Bench/Nature/Story/Nature Reviews Cardiology/19_2.txt
|
clip
|
19_2.txt
|
Inflammasomes in atrial fibrillation, inspired by the Review on p145.
Cover design: Vicky Summersby
|
MAC_Bench/Nature/Story/Nature Reviews Cardiology/20_10.txt
|
vith
|
20_10.txt
|
Cardiac sarcomeric proteins, inspired by the Review on p9
Cover design: Vicky Summersby
|
MAC_Bench/Nature/Story/Nature Reviews Cardiology/22_2.txt
|
groundtruth
|
22_2.txt
|
New CRISPR tools, inspired by the Review on p505.
Cover design: Vicky Summersby.
|
MAC_Bench/Nature/Story/Nature Reviews Cardiology/19_5.txt
|
vitg
|
19_5.txt
|
train
|
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY
|
21_6
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_6.png
|
D
|
Looking for biomarkers, inspired by the Roadmap on p727
Cover design: Laura Marshall
|
MAC_Bench/Nature/Story/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/19_2.txt
|
clip
|
19_2.txt
|
Focusing on pancreatic cancer, inspired by the Review on p469.
Cover design: Laura Marshall.
|
MAC_Bench/Nature/Story/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/18_6.txt
|
vitg
|
18_6.txt
|
Intersection between ALD and NAFLD/MASLD, inspired by the Review on p764.
Cover design: Laura Marshall
|
MAC_Bench/Nature/Story/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/20_1.txt
|
vith
|
20_1.txt
|
The expanding repertoire of bile acids, inspired by the Perspective on p493
Cover design: Laura Marshall
|
MAC_Bench/Nature/Story/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_6.txt
|
groundtruth
|
21_6.txt
|
train
|
NATURE REVIEWS GENETICS
|
25_6
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_6.png
|
C
|
Inspired by the Focus issue starting on p485.
Cover design: Patrick Morgan.
|
MAC_Bench/Nature/Story/NATURE REVIEWS GENETICS/24_5.txt
|
vitg
|
24_5.txt
|
Inspired by the Review on p739
Cover design: Sam Whitham
|
MAC_Bench/Nature/Story/NATURE REVIEWS GENETICS/24_2.txt
|
vith
|
24_2.txt
|
Inspired by the Reviews on p460 and p476
Cover design: Patrick Morgan
|
MAC_Bench/Nature/Story/NATURE REVIEWS GENETICS/25_6.txt
|
groundtruth
|
25_6.txt
|
'The end game' by Patrick Morgan, inspired by the Review on p693.
|
MAC_Bench/Nature/Story/NATURE REVIEWS GENETICS/13_3.txt
|
clip
|
13_3.txt
|
train
|
ACS Chemical Biology
|
2024_1
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/ACS Chemical Biology/2024_1.png
|
A
|
Switchback nucleic acid structures contain right-handed helical half-turns that are laterally arranged to form a globally left-handed structure with parallel strand orientation (set of blocks in the middle) in contrast to conventional duplexes that contain vertically stacked half-turns that form a right-handed structure with antiparallel strands (set of blocks on the right). The cover image was designed by Ella Maru Studio, Inc.
|
MAC_Bench/ACS/Story/ACS Chemical Biology/2024_1.txt
|
groundtruth
|
2024_1.txt
|
DOI: 10.1021/cb1003652) reveal the biosynthetic pathway of a key autoinducer, CAI-1 associated with the life cycle and virulence of human pathogen, Vibrio cholerae. Cover art designed by Mable Fok.
|
MAC_Bench/ACS/Story/ACS Chemical Biology/2011_9.txt
|
clip
|
2011_9.txt
|
This cover highlights the simultaneous observation of unusual -1 and -2 ribosomal frameshiftings on a slippery mRNA , via a novel mechanomagnetic detection of magnetic DNA rulers and centrifugal forces. Image Credit: Shoujun Xu
|
MAC_Bench/ACS/Story/ACS Chemical Biology/2017_7.txt
|
vith
|
2017_7.txt
|
The cover art illustrates the contribution of the non-covalent scaffold and the reactive warhead on the target engagement of covalent inhibitors as exemplified by covalent KRas G12C inhibitors. The background shows their target KRas G12C in a cellular environment approached by inhibitors representing different scaffold–warhead combinations.
|
MAC_Bench/ACS/Story/ACS Chemical Biology/2024_5.txt
|
vitg
|
2024_5.txt
|
train
|
NATURE REVIEWS MICROBIOLOGY
|
22_6
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_6.png
|
A
|
Targeting SARS-CoV-2, inspired by the Review on p391.
Cover design: Philip Patenall
|
MAC_Bench/Nature/Story/NATURE REVIEWS MICROBIOLOGY/22_6.txt
|
groundtruth
|
22_6.txt
|
COVER: Giant viruses, inspired by the Review on p721.
Cover design: Berkeley Lab.
|
MAC_Bench/Nature/Story/NATURE REVIEWS MICROBIOLOGY/20_1.txt
|
clip
|
20_1.txt
|
‘Tracking filoviruses’, inspired by the review article on page 365
Cover design: Philip Patenall
|
MAC_Bench/Nature/Story/NATURE REVIEWS MICROBIOLOGY/18_6.txt
|
ave_3
|
18_6.txt
|
SARS-CoV-2, inspired by the Focus issue.
Cover design: Philip Patenall.
|
MAC_Bench/Nature/Story/NATURE REVIEWS MICROBIOLOGY/21_10.txt
|
vitg
|
21_10.txt
|
train
|
ACS Materials Letters
|
2024_5
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/ACS Materials Letters/2024_5.png
|
D
|
It was recently demonstrated that perovskite single-crystals perform better than their polycrystalline thin-films counterparts due to their exceptional optoelectronic properties (low trap density, high carrier mobility, and long carrier lifetime and diffusion length). In this Review, Murali and Mohammed et al. provide a comprehensive overview of the growth methods, chemical stability, ion migration, and charge carrier dynamics of the perovskite single-crystals, as well as their potential applications in light-emitting diodes, photodetectors, and solar cells. The cover art shows a solar cell architecture where the perovskite single-crystal absorber layer is sandwiched between hole- and electron-transporting layers.
|
MAC_Bench/ACS/Story/ACS Materials Letters/2020_11.txt
|
ave_2
|
2020_11.txt
|
The image on the cover is an artistic representation of a 2D material, which typically show unique optical, mechanical, and chemical properties. In this issue, authors highlight the use of MXenes for applications in electronic and photonic devices, as well as a new synthetic method for metal dichalcogenide heterostructures. Credit: Shutterstock.com.
|
MAC_Bench/ACS/Story/ACS Materials Letters/2020_12.txt
|
vitg
|
2020_12.txt
|
The image on the cover is an artistic representation of bright fluorescent organic materials exhibiting red, yellow, and green emission for production of organic light-emitting devices. In this issue, authors have developed a styrene-based lamellar single crystal as a versatile optoelectronic material in optical pumping and light-emitting transistors. Credit: Shutterstock.com.
|
MAC_Bench/ACS/Story/ACS Materials Letters/2021_9.txt
|
clip
|
2021_9.txt
|
-scale WSe2 flakes-based light-gated transistors. Different LGT behaviors at above- and below-threshold light-gating with pulse modulations demonstrate a great deal of potential use in the fields of neuromorphic computing and logic operations. View the article.
|
MAC_Bench/ACS/Story/ACS Materials Letters/2024_5.txt
|
groundtruth
|
2024_5.txt
|
train
|
Nature Synthesis
|
3_2
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Synthesis/3_2.png
|
C
|
Data-driven automated synthesis
This Focus issue describes how techniques such as machine learning, artificial intelligence, robotics and automation can be combined to accelerate chemical and materials synthesis.
The cover image is from a Review Article describing the development of self-driving laboratories in chemical and materials sciences.
See Abolhasani and Kumacheva
Image: Milad Abolhasani, North Carolina State University. Cover Design: Amie Fernandez.
|
MAC_Bench/Nature/Story/Nature Synthesis/2_7.txt
|
vitg
|
2_7.txt
|
Green ammonia synthesis
Ammonia synthesis via the Haber–Bosch reaction produces approximately 1% of the world’s CO2 emissions, leading to intensive research to find more sustainable routes. This Focus issue overviews recent progress and challenges in green ammonia synthesis, looking at catalyst synthesis, resource allocation and different synthetic routes to produce green ammonia.
The cover image depicts an Article that describes the synthesis of core–shell nanocrystals with tunable single-atom alloy layers as electrocatalysts for green ammonia production.
See Gao et al.
Image: Xue Han, Huiyuan Zhu & Qiang Gao, University of Virginia. Cover Design: Amie Fernandez.
|
MAC_Bench/Nature/Story/Nature Synthesis/2_6.txt
|
clip
|
2_6.txt
|
Enzymatic enone synthesis
Chiral enones are produced, using flavin-dependent ene-reductases, through a desymmetrization approach. Enzymatic desaturation and reduction processes enable the synthesis of either enantiomer of the enone products from cyclohexanone or cyclohexadienone substrates.
See Zeng et al.
Image: Mudi Wang, National Institute of Biological Sciences. Cover design: Thomas Phillips
|
MAC_Bench/Nature/Story/Nature Synthesis/3_2.txt
|
groundtruth
|
3_2.txt
|
Strike a pose
Substrate docking into molecular-dynamics-simulated structures of enzyme variants is used to guide the design of mutations, which increases enantioselectivity in a C–H oxidation reaction by disfavouring binding poses leading to the unwanted enantiomer. This enzyme engineering approach enables selective oxidation of unactivated C–H bonds in cyclic amines to deliver high-value alcohol products for drug discovery and synthetic applications.
See Zhang et al.
Image: Yuan Zhang, Jeremy Robertson and Luet L. Wong, University of Oxford. Cover Design: Amie Fernandez.
|
MAC_Bench/Nature/Story/Nature Synthesis/1_1.txt
|
ave_0
|
1_1.txt
|
train
|
Structure
|
32_11
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Structure/32_11.png
|
A
|
On the cover: The study by Mukherjee et al. revealed that the PAS domain of the sensor histidine kinase FlrB of Vibrio
cholerae exhibits a unique architecture and forms a functional dimer. Heme binds FlrB
PAS as the sensory ligand to increase the swimming motility of V. cholerae. Cover
conceptualized by Dr. Jhimli Dasgupta and prepared by Baibhab Chakraborty.
|
MAC_Bench/Cell/Story/Structure/32_11.txt
|
groundtruth
|
32_11.txt
|
On the cover: In this special issue, we celebrate Structure’s 30th anniversary with a collection of reviews that highlight recent developments
in different areas of structural biology. We asked structural biologists what to expect
for the next decade in our Voices article. Cover image drawn by Julie Sung (scientific illustrator at Cell Press).
|
MAC_Bench/Cell/Story/Structure/31_2.txt
|
vitg
|
31_2.txt
|
On the cover: The I-domain, which is inserted into bacteriophage P22’s coat protein,
has multiple functional roles including serving as a folding nucleus and promoting
procapsid stability. The structure of the I-domain was solved by NMR spectroscopy
and then used to improve cryoEM models of the coat protein subunit. The cover presents
a cryoEM reconstruction of bacteriophage P22 with the magnifying glass showing a capsid
penton overlaid with the I-domain in cyan. The background is a light micrograph of
Salmonella cells, the host organism of phage P22. See Rizzo et al., pp. 830–841.
|
MAC_Bench/Cell/Story/Structure/22_7.txt
|
ave_1
|
22_7.txt
|
On the cover: The image shows a rendering of the structure of the Haliangium ochraceum bacterial microcompartment shell, the cryo-electron microscopy structure of which
Greber et al. (pp. 749–763) present in a paper in this issue of Structure. The shell is composed of different types of BMC proteins, which are shown in different
colors in the depiction. For one type, different conformational states, correlated
across the shell surface, can be discerned in the cryo-EM maps.
|
MAC_Bench/Cell/Story/Structure/27_8.txt
|
clip
|
27_8.txt
|
val
|
Nature Reviews Physics
|
6_1
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Reviews Physics/6_1.png
|
B
|
The cover of this issue is based on ab initio predictions of superconducting critical temperatures. See Pellegrini & Sanna
Image: Adapted from Pellegrini, C. & Sanna, A. Nat. Rev. Phys. (2024) Cover design: Susanne Harris.
|
MAC_Bench/Nature/Story/Nature Reviews Physics/6_5.txt
|
ave_0
|
6_5.txt
|
The cover of this issue illustrates the use of diamond sensors for many-body physics. See de Leon.
Image: Jared Rovny. Cover design: Susanne Harris.
|
MAC_Bench/Nature/Story/Nature Reviews Physics/6_1.txt
|
groundtruth
|
6_1.txt
|
The cover of this issue illustrates the physics and sustainability theme launching this month. See Editorial
Cover design: Susanne Harris.
|
MAC_Bench/Nature/Story/Nature Reviews Physics/5_10.txt
|
vitg
|
5_10.txt
|
The cover of this issue depicts hypernuclei decay events recorded in nuclear emulsion. See Saito et al.
Image: Takehiko Saito, RIKEN. Cover design: Charlotte Gurr.
|
MAC_Bench/Nature/Story/Nature Reviews Physics/3_1.txt
|
clip
|
3_1.txt
|
train
|
Cell Chemical Biology
|
31_2
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Cell Chemical Biology/31_2.png
|
B
|
On the cover: Join us in celebrating the 30th anniversary of Cell Chemical Biology with this special issue. The imagery reflects the multidisciplinary nature of the
journal, spanning all areas of biological and biomedical sciences from academia to
industry, collectively forming the vibrant field of chemical biology. Dive into the
editorial to explore the journal's rich history, ongoing achievements, and future directions.
Cover art by Julie Sung.
|
MAC_Bench/Cell/Story/Cell Chemical Biology/31_4.txt
|
ave_1
|
31_4.txt
|
On the cover: Bacterial respiration is the primary pathway to produce energy, coupling
with the electron transport chain (ETC) to transfer electrons. Targeting the ETC leads
to energy depletion and bacterial death. In this cover by Li et al., bacteria are depicted as the glowing light bulbs equipped with electrical circuits.
Antibacterial compounds block electron transfer leading to bacterial death, which
is like interruption of circuits causing the lights to turn off. Hence, targeting
the ETC is an attractive strategy to discover antibiotics. Image credit: Kui Zhu and
Qian Li.
|
MAC_Bench/Cell/Story/Cell Chemical Biology/31_2.txt
|
groundtruth
|
31_2.txt
|
On the cover: Join us in celebrating the 30th anniversary of Cell Chemical Biology with this special issue. The imagery reflects the multidisciplinary nature of the
journal, spanning all areas of biological and biomedical sciences from academia to
industry, collectively forming the vibrant field of chemical biology. Dive into the
editorial to explore the journal's rich history, ongoing achievements, and future directions.
Cover art by Julie Sung.
|
MAC_Bench/Cell/Story/Cell Chemical Biology/31_5.txt
|
vitg
|
31_5.txt
|
On the cover: The cover image shows the attack of small-molecule inhibitor spaceships
on the GPX4 space station in an attempt to trigger ferroptosis, a type of regulated
cell death driven by lipid peroxidation, indicated by the orange flames. See the paper
by Liu et al., 1680–1693; image courtesy of Nicoletta Barolini, Columbia University.
|
MAC_Bench/Cell/Story/Cell Chemical Biology/29_1.txt
|
clip
|
29_1.txt
|
train
|
Nature Cities
|
1_5
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Cities/1_5.png
|
D
|
Of skies and skylines
How we build and manage our cities affects air, climate and views. In this issue, Anna Zhelnina considers efforts to preserve the iconic skyline of Saint Petersburg, Russia, while Xia et al. document how many cities effectively benefit from the carbon mitigation efforts of other cities connected by supply chains.
See Zhelnina and Xia et al.
Image: Kirill Nikitin/Alamy Stock Photo. Cover design: Lauren Heslop
|
MAC_Bench/Nature/Story/Nature Cities/1_6.txt
|
clip
|
1_6.txt
|
Urbanization warming Indian cities
In a context of rapid industrialization, urbanization and climate change, Indian cities have experienced increasing warming. About 60% of the increased temperatures come from urbanization alone, especially in medium-sized cities.
See Sethi & Vinoj
Image: Dr. Vinoj. V, Indian Institute of Technology Bhubaneswar, INDIA. Cover design: Lauren Heslop
|
MAC_Bench/Nature/Story/Nature Cities/1_7.txt
|
ave_3
|
1_7.txt
|
Addressing heat exposure
Heat waves are becoming increasingly common in cities worldwide. Geogescu et al. estimate the potential to reduce the exposure of US city populations to extreme heat by comparing two methods: adapting in-place and mitigating local climate-warming activities.
See Georgescu et al.
Image: Sean Pavone/Alamy Stock Photo. Cover Design: Lauren Heslop
|
MAC_Bench/Nature/Story/Nature Cities/1_12.txt
|
vitg
|
1_12.txt
|
Cooling from natural areas
Overheating of cities is an increasing problem. Cao et al. investigate how neighboring rural land cover can mitigate and absorb urban heat.
See Yang et al.
Image: Shijie Cao, Southeast University, China. Cover design: Lauren Heslop.
|
MAC_Bench/Nature/Story/Nature Cities/1_5.txt
|
groundtruth
|
1_5.txt
|
train
|
Nature Aging
|
4_1
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Aging/4_1.png
|
B
|
FOXO and persistent chromatin remodeling
In this study, Martínez Corrales, Li and colleagues demonstrate that activation of the conserved pro-longevity transcription factor dFOXO solely in youth can trigger chromatin remodeling and transcriptional memory to curtail later-life mortality in female fruit flies. The cover image represents a female fly that survived to the very old age of 100 days owing to dFOXO activation.
See Martínez Corrales et al.
Cover image: Nazif Alic, University College London. Cover Design: Lauren Heslop
|
MAC_Bench/Nature/Story/Nature Aging/2_1.txt
|
ave_3
|
2_1.txt
|
Focus on reproductive aging
Reproductive aging is an important determinant of fertility span and overall health and wellbeing in older age. In this issue, Nature Aging presents a series of reviews and opinion pieces on recent advances and future directions in reproductive aging research. The cover image shows seasonally colored trees — a springtime tree in green, and autumn trees in brilliant yellow and red — that represent different stages of reproductive physiology in aging.
See Editorial
Image: Alex Whitworth. Cover design: Alex Whitworth
|
MAC_Bench/Nature/Story/Nature Aging/4_1.txt
|
groundtruth
|
4_1.txt
|
Inferring health trajectories
In this issue, Netta Mendelson Cohen et al. investigate individuals’ trajectories of healthy aging and age-related diseases. The researchers stitch together electronic health records with partial longitudinal coverage, using machine learning to untangle future healthy aging from chronic disease, and identify early indicators for healthy longevity. The cover image shows the study’s longevity-model features superimposed with representations of electronic health record information, which are connected via multiple solid or dotted lines that indicate differing propensities to drive the outputs of the models.
See Cohen et al.
Image: adapted from Nat. Aging https://doi.org/10.1038/s43587-023-00536-5 (2024), Springer Nature America (background and central graph), elenabs/iStock/Getty Images Plus (remaining elements). Cover Design: Lauren Heslop
|
MAC_Bench/Nature/Story/Nature Aging/4_12.txt
|
ave_2
|
4_12.txt
|
Aging in unity
The cover image of Nature Aging’s first issue illustrates the notion that aging concerns everyone, pointing to the need for social unity and joined research endeavors to solve issues and seize opportunities associated with human aging. Our first issue features research and opinion articles authored by biologists, clinicians, social scientists and civil society and industry leaders that reflect the breadth of our interests, from the intricate details of the core biology of aging to public health and societal questions associated with population aging.
See Editorial
Image: Smartboy10 / DigitalVisionVectors / Getty. Cover design: Lauren Heslop.
|
MAC_Bench/Nature/Story/Nature Aging/1_12.txt
|
clip
|
1_12.txt
|
train
|
Environmental Science & Technology
|
2025_1
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/Environmental Science & Technology/2025_1.png
|
A
|
NO3RR
|
MAC_Bench/ACS/Story/Environmental Science & Technology/2025_1.txt
|
groundtruth
|
2025_1.txt
|
This front cover depicts how machine learning and artificial intelligence are increasingly being applied to large environmentally relevant datasets for deciphering complex environmental relationships. The information uncovered and insights gained in system variables and behaviors help science discovery and solution advancement for environmental protection and sustainable development. ES&T is actively publishing transformational papers in this developing area of data science in environmental science and technology.
|
MAC_Bench/ACS/Story/Environmental Science & Technology/2022_11.txt
|
clip
|
2022_11.txt
|
This ES&T special issue presents new research on persistent organic pollutants (POPs) from some of the leading experts in the field.
|
MAC_Bench/ACS/Story/Environmental Science & Technology/2021_11.txt
|
vitg
|
2021_11.txt
|
Each year, ES&T selects exceptional papers from the previous year in the categories of Environmental Science, Environmental Technology, Environmental Policy, and Feature Articles for special recognition. This cover salutes the Best Papers of 2017!
|
MAC_Bench/ACS/Story/Environmental Science & Technology/2018_18.txt
|
vith
|
2018_18.txt
|
test
|
The Journal of Physical Chemistry C
|
2025_4
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/The Journal of Physical Chemistry C/2025_4.png
|
C
|
Zhao-Wu Tian Festschrift Virtual Special Issue
|
MAC_Bench/ACS/Story/The Journal of Physical Chemistry C/2024_50.txt
|
clip
|
2024_50.txt
|
Women Scientists in China Virtual Special Issue
|
MAC_Bench/ACS/Story/The Journal of Physical Chemistry C/2024_29.txt
|
vith
|
2024_29.txt
|
In this perspective, we discuss how one can correlate computational catalysis results with experimental techniques, such as calorimetry, temperature-programmed desorption, infrared spectroscopy, and XPS measurements. For example, configuration space mapping for the alloying of Ru into Fe(100) through a lattice gas model enables the construction of coverage-dependent microkinetic models involving oxygenated aromatics and identifies a catalytically relevant ground state structure. This structure features Fe (gold spheres) alloyed with Ru at the surface (pink spheres) and Ru at subsurface sites (large red spheres). The lattice gas model accounts for 2-body and 3-body interactions (examples shown), as well as higher-order interactions, which are quantified using first-principles calculations. The lateral interactions between oxygenated aromatics can also be quantified within a mean-field model, allowing for the correlation with core-level binding energy shifts observed in XPS measurements.
|
MAC_Bench/ACS/Story/The Journal of Physical Chemistry C/2025_4.txt
|
groundtruth
|
2025_4.txt
|
)
|
MAC_Bench/ACS/Story/The Journal of Physical Chemistry C/2020_4.txt
|
vitg
|
2020_4.txt
|
test
|
Nature Reviews Endocrinology
|
20_3
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_3.png
|
B
|
Exploring links between obesity and the kidney, inspired by the Review on p321.
Cover design: Jennie Vallis
|
MAC_Bench/Nature/Story/Nature Reviews Endocrinology/20_7.txt
|
vith
|
20_7.txt
|
The challenges of assessing adiposity, inspired by the Perspective on p615.
Cover design: Edward Byrne
|
MAC_Bench/Nature/Story/Nature Reviews Endocrinology/20_3.txt
|
groundtruth
|
20_3.txt
|
The WHO global targets for diabetes mellitus, inspired by the Viewpoint on p194.
Cover design: Jennie Vallis
|
MAC_Bench/Nature/Story/Nature Reviews Endocrinology/19_9.txt
|
clip
|
19_9.txt
|
Mapping progress in cell replacement therapies for T1DM, inspired by the Review on p14.
Cover design: Edward Byrne
|
MAC_Bench/Nature/Story/Nature Reviews Endocrinology/21_2.txt
|
vitg
|
21_2.txt
|
test
|
Nature Plants
|
10_1
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Plants/10_1.png
|
B
|
Retaining network resilience through evolution
Plant regulatory networks adapt to abiotic stresses such as salt conditions. Comparing the gene regulatory networks in Arabidopsis and Marchantia shows what is kept and what is lost over the evolutionary history of land plants.
SeeWu, T.-Y. et al.
Image: Daisuke Urano, Temasek Life Sciences Laboratory. Cover Design: Erin Dewalt.
|
MAC_Bench/Nature/Story/Nature Plants/7_7.txt
|
ave_2
|
7_7.txt
|
Rewiring for life on land
To colonize the land, plants had to evolve ways to obtain nutrients from barren terrains. The nutrient-response networks of liverworts, such as Marchantia polymorpha, show how this was achieved through extensive reorganization of the core components they share with distantly related, water-living algae
See Dong, Y. et al.
Image: Daisuke Urano, Temasek Life Sciences Laboratory. Cover design: Erin Dewalt
|
MAC_Bench/Nature/Story/Nature Plants/10_1.txt
|
groundtruth
|
10_1.txt
|
Five years of plant coverage
Nature Plants is entering its sixth year and volume. To celebrate our fifth birthday, this issue’s cover looks back at many of the most striking images that we have used for issues over the last five years.
See Editorial
Cover Design: L. Heslop.
|
MAC_Bench/Nature/Story/Nature Plants/6_12.txt
|
clip
|
6_12.txt
|
Fern relationships
Ferns are closely related to flowering plants but remain much less studied. Genome sequences of two ferns help redress this imbalance, and illuminate their mechanisms of defence and nitrogen fixation.
See Li et al.
Image: Laura Dijkhuizen. Cover Design: Bethany Vukomanovic.
|
MAC_Bench/Nature/Story/Nature Plants/4_6.txt
|
vith
|
4_6.txt
|
train
|
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