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The MACTAR Patient Preference Disability Questionnaire--an individualized functional priority approach for assessing improvement in physical disability in clinical trials in rheumatoid arthritis. | 14(3) | 446-51 | A new approach to assessing disability in arthritis that quantifies the functional priorities of the patient is described. Comparison against global improvement suggests that this instrument has the potential to detect small clinically important changes in function. | The Journal of rheumatology | [
{
"affiliation": "",
"forename": "P",
"identifier": "",
"initials": "P",
"lastname": "Tugwell"
},
{
"affiliation": "",
"forename": "C",
"identifier": "",
"initials": "C",
"lastname": "Bombardier"
},
{
"affiliation": "",
"forename": "W W",
"identifier": "",
"initials": "WW",
"lastname": "Buchanan"
},
{
"affiliation": "",
"forename": "C H",
"identifier": "",
"initials": "CH",
"lastname": "Goldsmith"
},
{
"affiliation": "",
"forename": "E",
"identifier": "",
"initials": "E",
"lastname": "Grace"
},
{
"affiliation": "",
"forename": "B",
"identifier": "",
"initials": "B",
"lastname": "Hanna"
}
] | 1987-06 | 3305931 | D001172:Arthritis, Rheumatoid / Q000175:diagnosis* / Q000188:drug therapy; D002986:Clinical Trials as Topic; D006305:Health Status Indicators; D006801:Humans; D012107:Research Design; D011795:Surveys and Questionnaires | D016430:Clinical Trial; D016428:Journal Article | [] | false | eng | J Rheumatol | 7501984 | 0315-162X | Canada | [] | "2024-08-13T08:46:10.177330Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||||
Association of limited joint mobility with Dupuytren's contracture in diabetes mellitus. | 14(3) | 582-5 | Limited joint mobility is a relatively recent addition to the list of other well known rheumatic disorders that may be associated with diabetes mellitus. In our study of 109 patients with diabetes, a higher prevalence of Dupuytren's contracture was found compared to nondiabetic subjects, but the difference was not statistically significant (p less than 0.1). An association between limited joint mobility and Dupuytren's contracture was shown. Patients with diabetes with Dupuytren's contracture showed no difference compared to those without Dupuytren's contracture with regard to sex, insulin dosage, metabolic control and presence of shoulder capsulitis. Limited joint mobility and Dupuytren's contracture may be associated with retinopathy. | The Journal of rheumatology | [
{
"affiliation": "",
"forename": "B",
"identifier": "",
"initials": "B",
"lastname": "Pal"
},
{
"affiliation": "",
"forename": "I D",
"identifier": "",
"initials": "ID",
"lastname": "Griffiths"
},
{
"affiliation": "",
"forename": "J",
"identifier": "",
"initials": "J",
"lastname": "Anderson"
},
{
"affiliation": "",
"forename": "W C",
"identifier": "",
"initials": "WC",
"lastname": "Dick"
}
] | 1987-06 | 3305932 | D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D003930:Diabetic Retinopathy / Q000150:complications; D004387:Dupuytren Contracture / Q000150:complications*; D005260:Female; D006801:Humans; D007328:Insulin / Q000008:administration & dosage; D007593:Joint Instability / Q000150:complications*; D008297:Male; D008875:Middle Aged; D010489:Periarthritis / Q000150:complications; D012737:Sex Factors; D012785:Shoulder Joint | D016428:Journal Article | D007328:Insulin | [] | false | eng | J Rheumatol | 7501984 | 0315-162X | Canada | [] | "2024-08-13T08:46:10.179404Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||
Proteoglycans from experimental osteoarthritic cartilage: degradation by neutral metalloproteases. | 14 Spec No() | 113-5 | This study deals with the analysis of the structure of cartilage proteoglycans in experimental osteoarthritis. We have demonstrated that chondrocytes in osteoarthritic cartilage synthesize proteoglycans which have the same functional characteristics as those of normal cartilage. Osteoarthritic cartilage contains metallodependent proteoglycan degrading enzymes, in both active and latent forms. These enzymes degrade both synthesized and endogenous proteoglycan macromolecules, as indicated by the reduced hydrodynamic size found in both proteoglycan populations in osteoarthritic cartilage treated with APMA. Our results also suggest the possibility that proteolytic degradation can occur at both the hyaluronate-binding region and in the chondroitin-sulfate-rich region of the proteoglycan core protein. | The Journal of rheumatology | [
{
"affiliation": "",
"forename": "J P",
"identifier": "",
"initials": "JP",
"lastname": "Pelletier"
},
{
"affiliation": "",
"forename": "J",
"identifier": "",
"initials": "J",
"lastname": "Martel-Pelletier"
},
{
"affiliation": "",
"forename": "C J",
"identifier": "",
"initials": "CJ",
"lastname": "Malemud"
}
] | 1987-05 | 3305933 | D000818:Animals; D002358:Cartilage, Articular / Q000378:metabolism*; D004285:Dogs; D010450:Endopeptidases / Q000378:metabolism; D008666:Metalloendopeptidases; D010003:Osteoarthritis / Q000378:metabolism*; D011509:Proteoglycans / Q000378:metabolism* | D016428:Journal Article; D013485:Research Support, Non-U.S. Gov't; D013487:Research Support, U.S. Gov't, P.H.S. | D011509:Proteoglycans; D010450:Endopeptidases; D008666:Metalloendopeptidases | [] | false | eng | J Rheumatol | 7501984 | 0315-162X | Canada | [
{
"agency": "NIA NIH HHS",
"country": "United States",
"grant_acronym": "AG",
"grant_id": "AG-02205"
}
] | "2024-08-13T08:46:10.180165Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||
Proteoglycan-degrading metalloproteases of human articular cartilage. | 14 Spec No() | 36-7 | Two metalloproteases have been purified from human articular cartilage. These attack the core protein of proteoglycan with pH optima of 5.3 and 7.2. The acid protease retains 40% of its activity at physiological pH. The two proteases are related in their properties of latency, activation, substrate specificity, and inhibitor pattern. They differ in pI, pH optimum, molecular weight, calcium requirement, and action on gelatin. Both activities are elevated 3-5 fold in osteoarthritic cartilage. Both proteases attack Ala-Leu and Tyr-Leu bonds in the B-chain of insulin. It is postulated that the entire family of metalloproteases acting on extracellular matrix shares a common specificity for Gly(Ala)-Leu(Ile) bonds. | The Journal of rheumatology | [
{
"affiliation": "",
"forename": "J F",
"identifier": "",
"initials": "JF",
"lastname": "Woessner"
},
{
"affiliation": "",
"forename": "W H",
"identifier": "",
"initials": "WH",
"lastname": "Azzo"
}
] | 1987-05 | 3305936 | D002358:Cartilage, Articular / Q000378:metabolism*; D010450:Endopeptidases / Q000378:metabolism*; D005109:Extracellular Matrix / Q000378:metabolism; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008666:Metalloendopeptidases; D010003:Osteoarthritis / Q000209:etiology / Q000378:metabolism; D011509:Proteoglycans / Q000378:metabolism*; D013379:Substrate Specificity | D016428:Journal Article; D013487:Research Support, U.S. Gov't, P.H.S. | D011509:Proteoglycans; D010450:Endopeptidases; D008666:Metalloendopeptidases | [] | false | eng | J Rheumatol | 7501984 | 0315-162X | Canada | [
{
"agency": "NIADDK NIH HHS",
"country": "United States",
"grant_acronym": "AM",
"grant_id": "AM-16940"
}
] | "2024-08-13T08:46:10.180876Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||
Degradation of extracellular matrix in osteoarthritis: 4 fundamental questions. | 14 Spec No() | 20-2 | The destruction of articular cartilage is a hallmark of osteoarthritis. In this process, cartilage fibrillation and eventual erosive lesions result from altered biomechanics generally thought to be preceded by alterations in the cartilage extracellular matrix. The irreversible cartilage changes are, in part, mediated by elevated proteolytic activities of acid and neutral metalloproteases that degrade proteoglycan and Type II collagen. Interestingly, an identical enzyme class is believed to participate in normal turnover of these extracellular matrix constituents. Thus, the control of synovial and cartilage protease activation has become of paramount importance in understanding the role these enzymes play in osteoarthritic pathology. | The Journal of rheumatology | [
{
"affiliation": "",
"forename": "C J",
"identifier": "",
"initials": "CJ",
"lastname": "Malemud"
},
{
"affiliation": "",
"forename": "J",
"identifier": "",
"initials": "J",
"lastname": "Martel-Pelletier"
},
{
"affiliation": "",
"forename": "J P",
"identifier": "",
"initials": "JP",
"lastname": "Pelletier"
}
] | 1987-05 | 3305934 | D000818:Animals; D002358:Cartilage, Articular / Q000378:metabolism; D003094:Collagen / Q000378:metabolism; D004791:Enzyme Inhibitors / Q000627:therapeutic use; D005109:Extracellular Matrix / Q000378:metabolism*; D006801:Humans; D010003:Osteoarthritis / Q000188:drug therapy / Q000378:metabolism* / Q000473:pathology; D010447:Peptide Hydrolases / Q000378:metabolism; D011509:Proteoglycans / Q000378:metabolism; D013583:Synovial Membrane / Q000378:metabolism | D016428:Journal Article; D013485:Research Support, Non-U.S. Gov't; D013487:Research Support, U.S. Gov't, P.H.S. | D004791:Enzyme Inhibitors; D011509:Proteoglycans; D003094:Collagen; D010447:Peptide Hydrolases | [] | false | eng | J Rheumatol | 7501984 | 0315-162X | Canada | [
{
"agency": "NIA NIH HHS",
"country": "United States",
"grant_acronym": "AG",
"grant_id": "AG-02205"
}
] | "2024-08-13T08:46:10.181803Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||
The proteoglycanase from human cartilage and cultured rabbit chondrocytes and its relation to osteoarthritis. | 14 Spec No() | 33-5 | The neutral metal dependent proteoglycanase predominates as the chief neutral protease present in human patellar cartilage or released by cultured rabbit chondrocytes into the culture medium. The cultured chondrocytes released the proteoglycanase mostly in latent form. Its activation resulted in splitting off a 10,000 dalton fragment. The chondrocytes also released inhibitory activity against the proteoglycanase. Most of it was released in the first 24 hours of culture, while most of the enzyme was released in the following 48 hours. Both the human cartilage and the rabbit chondrocyte enzyme occur in two molecular weight sizes, in equilibrium with each other. | The Journal of rheumatology | [
{
"affiliation": "",
"forename": "S",
"identifier": "",
"initials": "S",
"lastname": "Sapolsky"
},
{
"affiliation": "",
"forename": "C",
"identifier": "",
"initials": "C",
"lastname": "Malemud"
},
{
"affiliation": "",
"forename": "M",
"identifier": "",
"initials": "M",
"lastname": "Sheff"
}
] | 1987-05 | 3305935 | D000818:Animals; D002358:Cartilage, Articular / Q000201:enzymology*; D002478:Cells, Cultured; D010450:Endopeptidases / Q000378:metabolism*; D006801:Humans; D008666:Metalloendopeptidases; D008970:Molecular Weight; D010003:Osteoarthritis / Q000201:enzymology* / Q000209:etiology; D011480:Protease Inhibitors; D011817:Rabbits | D016428:Journal Article; D013487:Research Support, U.S. Gov't, P.H.S. | D011480:Protease Inhibitors; D010450:Endopeptidases; C022474:proteoglycan-degrading metalloendopeptidases; D008666:Metalloendopeptidases | [] | false | eng | J Rheumatol | 7501984 | 0315-162X | Canada | [
{
"agency": "NIA NIH HHS",
"country": "United States",
"grant_acronym": "AG",
"grant_id": "AG-00961"
},
{
"agency": "NIA NIH HHS",
"country": "United States",
"grant_acronym": "AG",
"grant_id": "AG-02205"
},
{
"agency": "NIADDK NIH HHS",
"country": "United States",
"grant_acronym": "AM",
"grant_id": "AM-21312"
}
] | "2024-08-13T08:46:10.182716Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||
Matrix metalloproteinases 1, 2, and 3 from rheumatoid synovial cells are sufficient to destroy joints. | 14 Spec No() | 41-2 | A neutral metalloproteinase has been isolated and purified from adherent rheumatoid synovial cells in culture. This protease, named matrix metalloproteinase 3, (MMP-3) degrades gelatin, proteoglycan, fibronectin, type IV collagen, laminin, and the N propeptide of type I procollagen. It can be separated from MMP-2 (a potent gelatinase), and MMP-1, an interstitial collagenase. MMP-3 is released from cells as a proenzyme of 55 Kda. Activation by trypsin or organic mercurials produces 2 active species of 45 Kda and 28 Kda. The enzyme contains zinc as an intrinsic component and requires calcium for conformational stability. In concert, active MMP-1, -2, and -3 can destroy all significant structural proteins of joint structures. | The Journal of rheumatology | [
{
"affiliation": "",
"forename": "Y",
"identifier": "",
"initials": "Y",
"lastname": "Okada"
},
{
"affiliation": "",
"forename": "H",
"identifier": "",
"initials": "H",
"lastname": "Nagase"
},
{
"affiliation": "",
"forename": "E D",
"identifier": "",
"initials": "ED",
"lastname": "Harris"
}
] | 1987-05 | 3305938 | D001172:Arthritis, Rheumatoid / Q000201:enzymology* / Q000209:etiology; D010450:Endopeptidases / Q000378:metabolism*; D005109:Extracellular Matrix / Q000201:enzymology; D006801:Humans; D008666:Metalloendopeptidases; D013583:Synovial Membrane / Q000201:enzymology* | D016428:Journal Article; D013487:Research Support, U.S. Gov't, P.H.S. | D010450:Endopeptidases; D008666:Metalloendopeptidases | [] | false | eng | J Rheumatol | 7501984 | 0315-162X | Canada | [
{
"agency": "NIADDK NIH HHS",
"country": "United States",
"grant_acronym": "AM",
"grant_id": "AM 33714"
}
] | "2024-08-13T08:46:10.183492Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||
Neutral proteases in human osteoarthritic synovium: quantification and characterization. | 14 Spec No() | 38-40 | In this study, we measured the levels of neutral metallo- and serine proteases in human osteoarthritic synovium. These enzymes degrade both collagen and proteoglycan macromolecules. They were analyzed by tissue culture methodology and direct extraction. We have demonstrated that in human osteoarthritic synovium, there is a correlation between neutral enzyme activity and the severity of synovial inflammation. Tissue culture studies have shown that the human osteoarthritic synovial membrane produces metalloproteases, such as collagenase, proteoglycanase and gelatinase. These enzymes were further characterized by their molecular weight. Extracts of osteoarthritic synovial tissues showed the presence of serine proteases, with apparent Mr of 25,000. | The Journal of rheumatology | [
{
"affiliation": "",
"forename": "J",
"identifier": "",
"initials": "J",
"lastname": "Martel-Pelletier"
},
{
"affiliation": "",
"forename": "J P",
"identifier": "",
"initials": "JP",
"lastname": "Pelletier"
}
] | 1987-05 | 3305937 | D010450:Endopeptidases / Q000378:metabolism; D006801:Humans; D008666:Metalloendopeptidases; D008970:Molecular Weight; D010003:Osteoarthritis / Q000201:enzymology*; D010447:Peptide Hydrolases / Q000378:metabolism*; D012697:Serine Endopeptidases; D013583:Synovial Membrane / Q000201:enzymology* | D016428:Journal Article; D013485:Research Support, Non-U.S. Gov't | D010450:Endopeptidases; D010447:Peptide Hydrolases; D012697:Serine Endopeptidases; D008666:Metalloendopeptidases | [] | false | eng | J Rheumatol | 7501984 | 0315-162X | Canada | [] | "2024-08-13T08:46:10.185418Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||
Levels of metalloproteases and tissue inhibitor of metalloproteases in human osteoarthritic cartilage. | 14 Spec No() | 43-4 | Human articular cartilage contains 2 distinct metalloproteases which degrade proteoglycan. One protease acts optimally at pH 5.3 and the other at pH 7.2. In addition, cartilage contains a tissue inhibitor of metalloproteases (TIMP) that inhibits both proteases. Methods have been developed for the estimation of metalloproteases and TIMP in extracts of cartilage prepared in buffered 2 M guanidine-HCl. In osteoarthritic cartilage, levels of the 2 metalloproteases increase 3-fold or more, while the level of TIMP remains constant. It is postulated that a balance is maintained between inhibitor and metalloprotease levels in normal cartilage and that in osteoarthritis increased secretion of proteases upsets this balance and results in degradation of the extracellular matrix. | The Journal of rheumatology | [
{
"affiliation": "",
"forename": "D D",
"identifier": "",
"initials": "DD",
"lastname": "Dean"
},
{
"affiliation": "",
"forename": "W",
"identifier": "",
"initials": "W",
"lastname": "Azzo"
},
{
"affiliation": "",
"forename": "J",
"identifier": "",
"initials": "J",
"lastname": "Martel-Pelletier"
},
{
"affiliation": "",
"forename": "J P",
"identifier": "",
"initials": "JP",
"lastname": "Pelletier"
},
{
"affiliation": "",
"forename": "J F",
"identifier": "",
"initials": "JF",
"lastname": "Woessner"
}
] | 1987-05 | 3305939 | D002358:Cartilage, Articular / Q000378:metabolism; D010450:Endopeptidases / Q000378:metabolism*; D006801:Humans; D008666:Metalloendopeptidases; D010003:Osteoarthritis / Q000378:metabolism*; D011480:Protease Inhibitors / Q000378:metabolism | D016428:Journal Article; D013485:Research Support, Non-U.S. Gov't; D013487:Research Support, U.S. Gov't, P.H.S. | D011480:Protease Inhibitors; D010450:Endopeptidases; D008666:Metalloendopeptidases | [] | false | eng | J Rheumatol | 7501984 | 0315-162X | Canada | [
{
"agency": "NIADDK NIH HHS",
"country": "United States",
"grant_acronym": "AM",
"grant_id": "AM-16940"
}
] | "2024-08-13T08:46:10.186206Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||
The role of serine proteinase in cartilage damage. | 14 Spec No() | 49-51 | Arthritic cartilage from experimental animals has been shown to have a decreased proteoglycan content, a decreased rate of proteoglycan synthesis, and a marked increase in an active serine proteinase when compared with normal articular cartilage. The serine proteinase is transferred from PMN cells into cartilage during the inflammatory response where it increased the rate of proteoglycan degradation and is eventually removed by interaction with the chondrocyte surface. The interaction also results in an inhibition of proteoglycan synthesis by the chondrocytes. Both these factors contribute to the loss of proteoglycan from arthritic cartilage. | The Journal of rheumatology | [
{
"affiliation": "",
"forename": "D A",
"identifier": "",
"initials": "DA",
"lastname": "Lowther"
},
{
"affiliation": "",
"forename": "A",
"identifier": "",
"initials": "A",
"lastname": "Sriratana"
},
{
"affiliation": "",
"forename": "J S",
"identifier": "",
"initials": "JS",
"lastname": "Bartholomew"
}
] | 1987-05 | 3305940 | D000818:Animals; D001168:Arthritis / Q000378:metabolism*; D002358:Cartilage, Articular / Q000378:metabolism*; D010450:Endopeptidases / Q000378:metabolism*; D009504:Neutrophils / Q000201:enzymology; D010196:Pancreatic Elastase / Q000378:metabolism; D011509:Proteoglycans / Q000378:metabolism; D011817:Rabbits; D012697:Serine Endopeptidases | D016428:Journal Article; D013485:Research Support, Non-U.S. Gov't | D011509:Proteoglycans; D010450:Endopeptidases; D012697:Serine Endopeptidases; D010196:Pancreatic Elastase | [] | false | eng | J Rheumatol | 7501984 | 0315-162X | Canada | [] | "2024-08-13T08:46:10.187147Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||
Immunologic modulation of cartilage metabolism. | 14 Spec No() | 83-5 | Preservation of the structural integrity of cartilage requires that metabolic homeostasis be maintained between chondrocyte anabolic and catabolic functions. This critical balance is perturbed in osteoarthritis (OA) in which synovial tissue and subchondral intratrabecular marrow often contain a focal and at times more diffuse mononuclear cell infiltration. Cytokines derived from T lymphocytes and monocytes have a capacity to: a) cause qualitative changes in and reversibly suppress chondrocyte proteoglycan, collagen, and non-collagen protein synthesis, and b) induce the synthesis and release of chondrocyte proteinases. Factors having comparable metabolic regulatory activity are produced by synovial tissue derived from idiopathic and secondary forms of OA. | The Journal of rheumatology | [
{
"affiliation": "",
"forename": "J H",
"identifier": "",
"initials": "JH",
"lastname": "Herman"
},
{
"affiliation": "",
"forename": "A M",
"identifier": "",
"initials": "AM",
"lastname": "Appel"
}
] | 1987-05 | 3305941 | D001688:Biological Products / Q000378:metabolism / Q000494:pharmacology; D002356:Cartilage / Q000187:drug effects / Q000276:immunology / Q000378:metabolism*; D016207:Cytokines; D006025:Glycosaminoglycans / Q000378:metabolism; D006801:Humans; D010003:Osteoarthritis / Q000276:immunology / Q000378:metabolism*; D011509:Proteoglycans / Q000378:metabolism; D013583:Synovial Membrane / Q000276:immunology / Q000378:metabolism | D016428:Journal Article; D013485:Research Support, Non-U.S. Gov't; D013487:Research Support, U.S. Gov't, P.H.S. | D001688:Biological Products; D016207:Cytokines; D006025:Glycosaminoglycans; D011509:Proteoglycans | [] | false | eng | J Rheumatol | 7501984 | 0315-162X | Canada | [
{
"agency": "NIADDK NIH HHS",
"country": "United States",
"grant_acronym": "AM",
"grant_id": "AM 16894"
},
{
"agency": "NIADDK NIH HHS",
"country": "United States",
"grant_acronym": "AM",
"grant_id": "AM 20615"
}
] | "2024-08-13T08:46:10.188010Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||
The role of mononuclear cell products as modulators of cartilage degradation. | 14 Spec No() | 86-7 | Human articular cartilage cultured in the presence of interleukin 1 (IL-1) produced from activated peripheral blood mononuclear cells, exhibits the concomitant release of a latent metalloproteinase and fragments of proteoglycan. The manner in which the activated form of the metalloproteinase degrades proteoglycan subunit and link protein suggests a role for this enzyme in cartilage degradation in vivo. While cartilage cultured in the continuous presence of purified IL-1 shows sustained release of metalloproteinase, tissue cultured in the presence of the total products released by activated mononuclear cells from some individuals showed initial stimulation followed by a decline, suggesting the presence of a modulator of IL-1 action. | The Journal of rheumatology | [
{
"affiliation": "",
"forename": "J S",
"identifier": "",
"initials": "JS",
"lastname": "Mort"
},
{
"affiliation": "",
"forename": "I K",
"identifier": "",
"initials": "IK",
"lastname": "Campbell"
},
{
"affiliation": "",
"forename": "A",
"identifier": "",
"initials": "A",
"lastname": "Guttman"
},
{
"affiliation": "",
"forename": "E E",
"identifier": "",
"initials": "EE",
"lastname": "Golds"
},
{
"affiliation": "",
"forename": "P J",
"identifier": "",
"initials": "PJ",
"lastname": "Roughley"
}
] | 1987-05 | 3305942 | D002358:Cartilage, Articular / Q000187:drug effects / Q000378:metabolism*; D046508:Culture Techniques; D010450:Endopeptidases / Q000378:metabolism; D006801:Humans; D007375:Interleukin-1 / Q000502:physiology*; D008666:Metalloendopeptidases; D011509:Proteoglycans / Q000378:metabolism | D016428:Journal Article; D013485:Research Support, Non-U.S. Gov't | D007375:Interleukin-1; D011509:Proteoglycans; D010450:Endopeptidases; D008666:Metalloendopeptidases | [] | false | eng | J Rheumatol | 7501984 | 0315-162X | Canada | [] | "2024-08-13T08:46:10.188970Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||
Graft-versus-host disease: a review. | 80(6) | 368-73 | Journal of the Royal Society of Medicine | [
{
"affiliation": "",
"forename": "A J",
"identifier": "",
"initials": "AJ",
"lastname": "Barrett"
}
] | 1987-06 | 3305944 | D000208:Acute Disease; D000818:Animals; D016026:Bone Marrow Transplantation; D002908:Chronic Disease; D006086:Graft vs Host Disease / Q000209:etiology* / Q000266:history / Q000473:pathology; D049673:History, 20th Century; D006801:Humans; D007938:Leukemia / Q000628:therapy | D016456:Historical Article; D016428:Journal Article; D016454:Review | 10.1177/014107688708000613 | [
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},
{
"citation": "Transplant Proc. 1973 Mar;5(1):865-8",
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"citation": "N Engl J Med. 1976 Oct 7;295(15):806-13",
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] | false | eng | J R Soc Med | 7802879 | 0141-0768 | England | [] | "2024-08-13T08:46:10.191123Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||||
Osteoarthritis, insulin and bone density. | 14 Spec No() | 91-3 | We earlier explored the crush and shear forces, associated with periarticular fibrous thickening, in nodal and other forms of osteoarthritis (OA). Looking for a generally acting growth stimulus, we described an association between hyperinsulinemia and DISH. In this study this association was confirmed, and a similar association between low insulin values and osteopenia emerged. A strong association between insulin levels and body weight was confirmed, which explained much of the difference in insulin levels between males and females. Very different kinds of OA were found in robust, hyperinsulinemic subjects as compared with osteopenic, hypoinsulinemic individuals, in which the arthropathy was more deforming, inflammatory, and erosive. | The Journal of rheumatology | [
{
"affiliation": "",
"forename": "H A",
"identifier": "",
"initials": "HA",
"lastname": "Smythe"
}
] | 1987-05 | 3305943 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001851:Bone Diseases, Metabolic / Q000097:blood / Q000150:complications; D001842:Bone and Bones / Q000473:pathology*; D005260:Female; D006801:Humans; D006946:Hyperinsulinism / Q000150:complications; D004057:Hyperostosis, Diffuse Idiopathic Skeletal / Q000097:blood / Q000150:complications; D007328:Insulin / Q000097:blood*; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000097:blood* / Q000473:pathology | D016428:Journal Article | D007328:Insulin | [] | false | eng | J Rheumatol | 7501984 | 0315-162X | Canada | [] | "2024-08-13T08:46:10.192423Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||
New inhibitors of human renin that contain novel Leu-Val replacements. | 30(9) | 1609-16 | Stereoselective syntheses of several nonpeptide fragments that function as Leu10-Val11 scissile bond replacements in human angiotensinogen are presented. The opening of N-protected aminoalkyl epoxide 3 with a variety of sulfur, oxygen, nitrogen, and carbon nucleophiles is a key reaction in the preparation of these novel fragments 4-8. The coupling of these fragments to protected dipeptides that mimic positions 8 and 9 in angiotensinogen produces inhibitors of human renin even though the molecules contain no functionality beyond what is formally the Val11 side chain of angiotensinogen. R groups that closely resemble that of the Val side chain are preferable; thus, isopropyl greater than or equal to higher alkyl greater than phenyl greater than substituted phenyl. Sulfur is the best X group; oxidation leads to slight (X = SO2) and significant (X = SO) decreases in inhibitory potency. One such inhibitor, 60, has an IC50 of 13 nM when tested with purified human renin at pH 6.0. The significant activity of these small inhibitors is thought to be due in part to the hydroxyl group of the fragment functioning as a transition-state analogue. Of these, the inhibitors that contain histidine show marked selectivity toward renin over a related aspartic proteinase, pepsin. | Journal of medicinal chemistry | [
{
"affiliation": "",
"forename": "J R",
"identifier": "",
"initials": "JR",
"lastname": "Luly"
},
{
"affiliation": "",
"forename": "N",
"identifier": "",
"initials": "N",
"lastname": "Yi"
},
{
"affiliation": "",
"forename": "J",
"identifier": "",
"initials": "J",
"lastname": "Soderquist"
},
{
"affiliation": "",
"forename": "H",
"identifier": "",
"initials": "H",
"lastname": "Stein"
},
{
"affiliation": "",
"forename": "J",
"identifier": "",
"initials": "J",
"lastname": "Cohen"
},
{
"affiliation": "",
"forename": "T J",
"identifier": "",
"initials": "TJ",
"lastname": "Perun"
},
{
"affiliation": "",
"forename": "J J",
"identifier": "",
"initials": "JJ",
"lastname": "Plattner"
}
] | 1987-09 | 3305946 | D000595:Amino Acid Sequence; D000808:Angiotensinogen / Q000031:analogs & derivatives* / Q000494:pharmacology; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D006801:Humans; D007930:Leucine; D012083:Renin / Q000037:antagonists & inhibitors*; D013237:Stereoisomerism; D014633:Valine | D016428:Journal Article | D004791:Enzyme Inhibitors; D000808:Angiotensinogen; D012083:Renin; D007930:Leucine; D014633:Valine | 10.1021/jm00392a015 | [] | false | eng | J Med Chem | 9716531 | 0022-2623 | United States | [] | "2024-08-13T08:46:10.193546Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||
Structure-activity relationships in an imidazole-based series of thromboxane synthase inhibitors. | 30(9) | 1588-95 | Analogues of 4-[[2-(1H-imidazol-1-yl)-1-[[(4-methoxyphenyl)methoxy]methyl] ethoxy]methyl]benzoic acid (5m) were prepared and evaluated as thromboxane synthase inhibitors. A series of esters of 5m showed a parabolic relationship between lipophilicity and inhibition of TxB2 generation in intact platelets, with activities up to 50 times greater than that of dazoxiben. However, on administration to rabbits the ethyl ester 5d had a short duration of action, due to rapid metabolism and excretion via deesterification and beta-glucuronidation. Attempts at replacing the carboxylate group with other potential pharmacophores were unsuccessful. | Journal of medicinal chemistry | [
{
"affiliation": "",
"forename": "P W",
"identifier": "",
"initials": "PW",
"lastname": "Manley"
},
{
"affiliation": "",
"forename": "N M",
"identifier": "",
"initials": "NM",
"lastname": "Allanson"
},
{
"affiliation": "",
"forename": "R F",
"identifier": "",
"initials": "RF",
"lastname": "Booth"
},
{
"affiliation": "",
"forename": "P E",
"identifier": "",
"initials": "PE",
"lastname": "Buckle"
},
{
"affiliation": "",
"forename": "E J",
"identifier": "",
"initials": "EJ",
"lastname": "Kuzniar"
},
{
"affiliation": "",
"forename": "N",
"identifier": "",
"initials": "N",
"lastname": "Lad"
},
{
"affiliation": "",
"forename": "S M",
"identifier": "",
"initials": "SM",
"lastname": "Lai"
},
{
"affiliation": "",
"forename": "D O",
"identifier": "",
"initials": "DO",
"lastname": "Lunt"
},
{
"affiliation": "",
"forename": "D P",
"identifier": "",
"initials": "DP",
"lastname": "Tuffin"
}
] | 1987-09 | 3305945 | D000818:Animals; D001792:Blood Platelets / Q000187:drug effects / Q000201:enzymology; D002851:Chromatography, High Pressure Liquid; D003094:Collagen / Q000494:pharmacology; D011464:Epoprostenol / Q000096:biosynthesis; D006801:Humans; D007093:Imidazoles / Q000494:pharmacology*; D011817:Rabbits; D013329:Structure-Activity Relationship; D013928:Thromboxane A2 / Q000096:biosynthesis; D013929:Thromboxane B2 / Q000097:blood; D013930:Thromboxane-A Synthase / Q000037:antagonists & inhibitors* | D016428:Journal Article | D007093:Imidazoles; D013929:Thromboxane B2; D013928:Thromboxane A2; C053318:1-(2,3-bis((4-methoxyphenyl)methoxy)propyl)-1H-imidazole; D003094:Collagen; D011464:Epoprostenol; D013930:Thromboxane-A Synthase | 10.1021/jm00392a011 | [] | false | eng | J Med Chem | 9716531 | 0022-2623 | United States | [] | "2024-08-13T08:46:10.194864Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||
Fluoro ketone containing peptides as inhibitors of human renin. | 30(9) | 1617-22 | The pentapeptide BOC-Phe-Phe-difluorostatone-Leu-Phe-NH2 has been prepared and found to be a potent inhibitor of human renin. This compound contains a difluoromethylene ketone group that exists predominantly in the hydrated form in water. The difluorostatone-containing peptide is 7-fold and 22-fold more potent than the analogous statine- and statone-containing peptides, respectively. Structure/activity analysis of the most potent inhibitor was carried out by replacing some of the peptide bonds with trans-alkenes. In all cases, a dramatic loss in binding to renin was observed. A number of statine-containing inhibitors of renin have been reported and this work suggests that the replacement of statine with difluorostatone will yield more potent compounds. | Journal of medicinal chemistry | [
{
"affiliation": "",
"forename": "K",
"identifier": "",
"initials": "K",
"lastname": "Fearon"
},
{
"affiliation": "",
"forename": "A",
"identifier": "",
"initials": "A",
"lastname": "Spaltenstein"
},
{
"affiliation": "",
"forename": "P B",
"identifier": "",
"initials": "PB",
"lastname": "Hopkins"
},
{
"affiliation": "",
"forename": "M H",
"identifier": "",
"initials": "MH",
"lastname": "Gelb"
}
] | 1987-09 | 3305947 | D000595:Amino Acid Sequence; D000596:Amino Acids; D006801:Humans; D007659:Ketones / Q000494:pharmacology*; D007668:Kidney / Q000201:enzymology; D007930:Leucine; D009682:Magnetic Resonance Spectroscopy; D012083:Renin / Q000037:antagonists & inhibitors*; D013329:Structure-Activity Relationship; D014633:Valine | D016428:Journal Article; D013487:Research Support, U.S. Gov't, P.H.S. | D000596:Amino Acids; D007659:Ketones; D012083:Renin; D007930:Leucine; D014633:Valine; C013165:statine | 10.1021/jm00392a016 | [] | false | eng | J Med Chem | 9716531 | 0022-2623 | United States | [
{
"agency": "NIGMS NIH HHS",
"country": "United States",
"grant_acronym": "GM",
"grant_id": "GM-35466"
},
{
"agency": "NHLBI NIH HHS",
"country": "United States",
"grant_acronym": "HL",
"grant_id": "HL-36235"
},
{
"agency": "NCRR NIH HHS",
"country": "United States",
"grant_acronym": "RR",
"grant_id": "RR01614"
}
] | "2024-08-13T08:46:10.197043Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||
Newly recognized route of arbovirus dissemination from the mosquito (Diptera: Culicidae) midgut. | 24(4) | 431-2 | Journal of medical entomology | [
{
"affiliation": "",
"forename": "W S",
"identifier": "",
"initials": "WS",
"lastname": "Romoser"
},
{
"affiliation": "",
"forename": "M E",
"identifier": "",
"initials": "ME",
"lastname": "Faran"
},
{
"affiliation": "",
"forename": "C L",
"identifier": "",
"initials": "CL",
"lastname": "Bailey"
}
] | 1987-07 | 3305948 | D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D002043:Bunyaviridae / Q000502:physiology*; D003465:Culex / Q000382:microbiology*; D004064:Digestive System / Q000382:microbiology; D007124:Immunoenzyme Techniques; D012296:Rift Valley fever virus / Q000276:immunology / Q000502:physiology* | D016428:Journal Article; D013486:Research Support, U.S. Gov't, Non-P.H.S. | D000956:Antigens, Viral | 10.1093/jmedent/24.4.431 | [] | false | eng | J Med Entomol | 0375400 | 0022-2585 | England | [] | "2024-08-13T08:46:10.197785Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||
Field evaluation of enzyme-linked immunosorbent assays for Plasmodium falciparum and Plasmodium vivax sporozoites in mosquitoes (Diptera: Culicidae) from Papua New Guinea. | 24(4) | 433-7 | Journal of medical entomology | [
{
"affiliation": "",
"forename": "R A",
"identifier": "",
"initials": "RA",
"lastname": "Wirtz"
},
{
"affiliation": "",
"forename": "T R",
"identifier": "",
"initials": "TR",
"lastname": "Burkot"
},
{
"affiliation": "",
"forename": "P M",
"identifier": "",
"initials": "PM",
"lastname": "Graves"
},
{
"affiliation": "",
"forename": "R G",
"identifier": "",
"initials": "RG",
"lastname": "Andre"
}
] | 1987-07 | 3305949 | D000818:Animals; D000852:Anopheles / Q000469:parasitology*; D004797:Enzyme-Linked Immunosorbent Assay; D010219:Papua New Guinea; D010963:Plasmodium falciparum / Q000302:isolation & purification*; D010966:Plasmodium vivax / Q000302:isolation & purification*; D013045:Species Specificity | D003160:Comparative Study; D016428:Journal Article; D013485:Research Support, Non-U.S. Gov't; D013486:Research Support, U.S. Gov't, Non-P.H.S. | 10.1093/jmedent/24.4.433 | [] | false | eng | J Med Entomol | 0375400 | 0022-2585 | England | [] | "2024-08-13T08:46:10.198483Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||||
A review of the genus Meringis (Siphonaptera: Hystrichopsyllidae). | 24(4) | 467-76 | Journal of medical entomology | [
{
"affiliation": "",
"forename": "R B",
"identifier": "",
"initials": "RB",
"lastname": "Eads"
},
{
"affiliation": "",
"forename": "E G",
"identifier": "",
"initials": "EG",
"lastname": "Campos"
},
{
"affiliation": "",
"forename": "G O",
"identifier": "",
"initials": "GO",
"lastname": "Maupin"
}
] | 1987-07 | 3305950 | D000818:Animals; D005260:Female; D008297:Male; D005423:Siphonaptera / Q000033:anatomy & histology / Q000145:classification* | D016428:Journal Article; D016454:Review | 10.1093/jmedent/24.4.467 | [] | false | eng | J Med Entomol | 0375400 | 0022-2585 | England | [] | "2024-08-13T08:46:10.199354Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||||
[Echographic changes in the wall of the gallbladder in hepatitis]. | 37(1) | 26-32 | Le Journal medical libanais. The Lebanese medical journal | [
{
"affiliation": "",
"forename": "K",
"identifier": "",
"initials": "K",
"lastname": "Khouri"
},
{
"affiliation": "",
"forename": "R",
"identifier": "",
"initials": "R",
"lastname": "Sayegh"
},
{
"affiliation": "",
"forename": "J",
"identifier": "",
"initials": "J",
"lastname": "Abi-Rached"
}
] | 1987 | 3305951 | D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D005704:Gallbladder / Q000473:pathology*; D006505:Hepatitis / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D014463:Ultrasonography | D002363:Case Reports; D004740:English Abstract; D016428:Journal Article | [] | false | fre | Les modifications échographiques de la paroi de la vésicule biliaire au cours des hépatites. | J Med Liban | 0375352 | 0023-9852 | Lebanon | [] | "2024-08-13T08:46:10.199959Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||||
Bovine tuberculosis in a wild baboon population: epidemiological aspects. | 16(4) | 229-35 | A follow-up of an outbreak of Mycobacterium bovis in a population of feral baboons in Kenya was undertaken after one year by necropsy of euthanized, clinically ill animals, and tuberculin testing of others. It was concluded that the source of the infection was animals feeding on village slaughterhouse offal of M. bovis infected cows. Secondary (direct) baboon-baboon transfer of the disease appeared to be minimal or nonexistent. | Journal of medical primatology | [
{
"affiliation": "",
"forename": "R M",
"identifier": "",
"initials": "RM",
"lastname": "Sapolsky"
},
{
"affiliation": "",
"forename": "J G",
"identifier": "",
"initials": "JG",
"lastname": "Else"
}
] | 1987 | 3305954 | D000818:Animals; D004196:Disease Outbreaks / Q000662:veterinary*; D005260:Female; D005500:Follow-Up Studies; D007630:Kenya; D008297:Male; D008992:Monkey Diseases / Q000453:epidemiology* / Q000209:etiology; D009163:Mycobacterium bovis / Q000302:isolation & purification; D010215:Papio; D014374:Tuberculin Test / Q000662:veterinary; D014376:Tuberculosis / Q000453:epidemiology / Q000209:etiology / Q000662:veterinary* | D016428:Journal Article; D013485:Research Support, Non-U.S. Gov't; D013487:Research Support, U.S. Gov't, P.H.S. | [] | false | eng | J Med Primatol | 0320626 | 0047-2565 | Denmark | [
{
"agency": "NCRR NIH HHS",
"country": "United States",
"grant_acronym": "RR",
"grant_id": "RR-000165"
}
] | "2024-08-13T08:46:10.200688Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||||
The construction and operation of a simple inexpensive slam freezing device for electron microscopy. | 147(Pt 1) | 103-8 | A simple and inexpensive slam freezing device has been constructed that allows consistently good rapid freezing of uncryoprotected tissue. The device employs a dry liquid-nitrogen-cooled cooper surface and a slamming plunger designed to provide rapid and uniform tissue to metal contact. | Journal of microscopy | [
{
"affiliation": "",
"forename": "D P",
"identifier": "",
"initials": "DP",
"lastname": "Allison"
},
{
"affiliation": "",
"forename": "C S",
"identifier": "",
"initials": "CS",
"lastname": "Daw"
},
{
"affiliation": "",
"forename": "M C",
"identifier": "",
"initials": "MC",
"lastname": "Rorvik"
}
] | 1987-07 | 3305955 | D000818:Animals; D003300:Copper; D005615:Freezing; D006652:Histological Techniques / Q000295:instrumentation*; D051379:Mice; D008854:Microscopy, Electron / Q000295:instrumentation / Q000379:methods; D009206:Myocardium / Q000648:ultrastructure* | D016428:Journal Article; D013486:Research Support, U.S. Gov't, Non-P.H.S. | D003300:Copper | 10.1111/j.1365-2818.1987.tb02822.x | [] | false | eng | J Microsc | 0204522 | 0022-2720 | England | [] | "2024-08-13T08:46:10.201490Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||
Measurement of increased uptake of osmium in skin and in a gelatin model 'tissue' treated with tannic acid. | 147(Pt 1) | 109-14 | The effect of tannic acid (TA) on the deposition of osmium was studied in discs of hamster skin and in fixed gelatin. Pieces of skin treated with 1.0% TA before OsO4 fixation absorbed almost twice as much as untreated pieces. Gelatin, used here as a model 'tissue' showed an even greater degree of enhancement. Treated gelatin capsule halves and strips took up 4-6 times as much osmium as untreated ones. The deposition of osmium was verified by neutron activation analysis. | Journal of microscopy | [
{
"affiliation": "",
"forename": "T",
"identifier": "",
"initials": "T",
"lastname": "Caceci"
},
{
"affiliation": "",
"forename": "K E",
"identifier": "",
"initials": "KE",
"lastname": "Frankum"
}
] | 1987-07 | 3305956 | D000818:Animals; D006224:Cricetinae; D005780:Gelatin; D006652:Histological Techniques; D047348:Hydrolyzable Tannins; D008647:Mesocricetus; D008954:Models, Biological; D009992:Osmium; D012867:Skin / Q000648:ultrastructure* | D016428:Journal Article; D013485:Research Support, Non-U.S. Gov't; D013487:Research Support, U.S. Gov't, P.H.S. | D047348:Hydrolyzable Tannins; D009992:Osmium; D005780:Gelatin | 10.1111/j.1365-2818.1987.tb02823.x | [] | false | eng | J Microsc | 0204522 | 0022-2720 | England | [] | "2024-08-13T08:46:10.203288Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||
Techniques for combining light microscopy and scanning electron microscopy: a survey of the literature. | 147(Pt 1) | 5-14 | A survey of methods combining light microscopy and scanning electron microscopy is presented. A simple correlation is made when two preparations from adjacent parts of one specimen are investigated in two different microscopes. A more sophisticated method is the consecutive investigation of one specimen with two microscopes. A major problem in this method is the relocation of the area of interest. Several authors have presented solutions for this problem. It is preferable when one preparation is investigated in only one instrument, combining the two microscopical (LM and SEM) techniques, thus making relocation redundant. | Journal of microscopy | [
{
"affiliation": "",
"forename": "C H",
"identifier": "",
"initials": "CH",
"lastname": "Wouters"
}
] | 1987-07 | 3305957 | D008853:Microscopy / Q000295:instrumentation / Q000379:methods*; D008855:Microscopy, Electron, Scanning / Q000295:instrumentation / Q000379:methods* | D016428:Journal Article; D016454:Review | 10.1111/j.1365-2818.1987.tb02814.x | [] | false | eng | J Microsc | 0204522 | 0022-2720 | England | [] | "2024-08-13T08:46:10.203890Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||
Preparation of the mammalian organ of Corti for scanning electron microscopy. | 147(Pt 1) | 89-101 | The effect of various standard tissue preparation procedures for scanning microscopy on the morphology of the mammalian organ of Corti has been examined. Comparison was made of (i) different fixatives: glutaraldehyde (GA) alone, osmium (Os) alone, GA and Os together and GA followed by Os; (ii) freeze-drying (FD) versus critical point-drying (CPD); (iii) ligand binding of osmium with thiocarbohydrazide (TOTO procedure) versus sputter coating to provide a conductive coat. Results were assessed in terms of known structural parameters in fresh tissue. It is shown: (i) that double fixation, either GA, Os together or GA followed by Os, consistently produced less tissue distortion than either fixative alone, (ii) that FD produced less shrinkage of the tissue than CPD, and (iii) that the TOTO procedure appeared to rigidify the tissue and enhanced preservation of the morphology. | Journal of microscopy | [
{
"affiliation": "",
"forename": "S",
"identifier": "",
"initials": "S",
"lastname": "Davies"
},
{
"affiliation": "",
"forename": "A",
"identifier": "",
"initials": "A",
"lastname": "Forge"
}
] | 1987-07 | 3305958 | D000818:Animals; D006168:Guinea Pigs; D006652:Histological Techniques; D007202:Indicators and Reagents; D008854:Microscopy, Electron / Q000379:methods; D008855:Microscopy, Electron, Scanning / Q000379:methods; D009925:Organ of Corti / Q000648:ultrastructure* | D003160:Comparative Study; D016428:Journal Article; D013485:Research Support, Non-U.S. Gov't | D007202:Indicators and Reagents | 10.1111/j.1365-2818.1987.tb02821.x | [] | false | eng | J Microsc | 0204522 | 0022-2720 | England | [] | "2024-08-13T08:46:10.204513Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||
Influence of neighbouring base sequence on N-methyl-N'-nitro-N-nitrosoguanidine mutagenesis in the lacI gene of Escherichia coli. | 194(3) | 385-90 | N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced forward mutations within the first 540 base-pairs of the lacI gene of Escherichia coli were cloned and sequenced. In total, 167 MNNG-induced independent mutations were characterized, with G.C to A.T transitions accounting for all but three of the mutations. This mutagenic specificity is consistent with the mispairing predicted by the methylation of the O6 position of guanine. The characterization of such large numbers of mutations permitted an analysis of the influence of local DNA sequence on mutagenesis. This analysis revealed a strong influence by the 5' flanking base. On average, guanine residues preceded (5') by a guanine or an adenine residue were, respectively, nine times and five times more likely to mutate after treatment with MNNG than those preceded by a pyrimidine residue. | Journal of molecular biology | [
{
"affiliation": "",
"forename": "P A",
"identifier": "",
"initials": "PA",
"lastname": "Burns"
},
{
"affiliation": "",
"forename": "A J",
"identifier": "",
"initials": "AJ",
"lastname": "Gordon"
},
{
"affiliation": "",
"forename": "B W",
"identifier": "",
"initials": "BW",
"lastname": "Glickman"
}
] | 1987-04-05 | 3305959 | D001482:Base Composition / Q000187:drug effects; D001483:Base Sequence / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics*; D005798:Genes, Bacterial / Q000187:drug effects*; D008769:Methylnitronitrosoguanidine / Q000494:pharmacology*; D009154:Mutation | D016428:Journal Article; D013485:Research Support, Non-U.S. Gov't | D008769:Methylnitronitrosoguanidine | 10.1016/0022-2836(87)90668-1 | [] | false | eng | J Mol Biol | 2985088R | 0022-2836 | Netherlands | [] | "2024-08-13T08:46:10.205718Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||
A computerized method for processing of spectrally analysed Doppler-shifted signals from insonated arteries. | 11(3) | 108-12 | A microcomputer-based technique is described for processing blood-velocity signals after they have been spectrally analysed. The system consists of a real-time dual channel spectrum analyser interfaced to a BBC model B microcomputer. The microcomputer is programmed to store and display in real-time spectral information received from the analyser. Stored sonograms can be readily retrieved from memory on request and displayed on the microcomputer's TV-monitor for viewing and/or subsequent numerate interogation. The proposed system is software controlled and is therefore both versatile and expandable, enabling accommodation of future sonagram processing methods and new diagnostic parameters. | Journal of medical engineering & technology | [
{
"affiliation": "",
"forename": "S",
"identifier": "",
"initials": "S",
"lastname": "Kontis"
},
{
"affiliation": "",
"forename": "R G",
"identifier": "",
"initials": "RG",
"lastname": "Gosling"
}
] | 1987 | 3305952 | D001158:Arteries / Q000502:physiology*; D001698:Biomedical Engineering; D001783:Blood Flow Velocity; D003199:Computer Systems; D006801:Humans; D008838:Microcomputers; D014463:Ultrasonography / Q000379:methods*; D014652:Vascular Diseases / Q000175:diagnosis | D016428:Journal Article | 10.3109/03091908709018151 | [] | false | eng | J Med Eng Technol | 7702125 | 0309-1902 | England | [] | "2024-08-13T08:46:10.206469Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||
Statistical test for the comparison of samples from mutational spectra. | 194(3) | 391-6 | The Monte Carlo estimate of the p value of the hypergeometric test is described and advocated for the testing of the hypothesis that different treatments induce the same mutational spectrum. The hypergeometric test is a generalization of Fisher's "exact" test for tables with more than two rows and two columns. Use of the test is demonstrated by the analysis of data from the characterization of nonsense mutations in the lacI gene of Escherichia coli. Unlike the chi-square test, the hypergeometric test remains valid when applied to sparse cross-classification tables. The hypergeometric test has the most discrimination power of any statistical test that could be employed routinely to compare samples from mutational spectra. Direct application of the hypergeometric test to large cross-classification tables is excessively computation intensive, but estimation of its p value via Monte Carlo techniques is practical. | Journal of molecular biology | [
{
"affiliation": "",
"forename": "W T",
"identifier": "",
"initials": "WT",
"lastname": "Adams"
},
{
"affiliation": "",
"forename": "T R",
"identifier": "",
"initials": "TR",
"lastname": "Skopek"
}
] | 1987-04-05 | 3305960 | D004269:DNA, Bacterial / Q000235:genetics*; D004926:Escherichia coli / Q000235:genetics*; D008957:Models, Genetic; D009010:Monte Carlo Method; D009154:Mutation; D009874:Operations Research | D016428:Journal Article | D004269:DNA, Bacterial | 10.1016/0022-2836(87)90669-3 | [] | false | eng | J Mol Biol | 2985088R | 0022-2836 | Netherlands | [] | "2024-08-13T08:46:10.207270Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||
Transcription termination sites at the distal end of the leu operon of Salmonella typhimurium. | 194(3) | 443-52 | Transcription terminates at two different sites at the distal end of the leucine operon of Salmonella typhimurium. The first of these sites (leut), located 140 base-pairs past the end of leuD, contains a G + C-rich palindrome followed by a run of T residues in the non-coding strand. Termination at leut, both in vitro and in vivo, is independent of rho protein, but is stimulated by the NusA protein. The second termination site (leut'), located 145 base-pairs beyond the first, is rho-dependent both in vitro and in vivo, and is not influenced by NusA protein. The organization of transcription termination sites at the distal end of the leu operon (a rho-independent site followed by a rho-dependent site) is similar to that for the trp operon of Escherichia coli. | Journal of molecular biology | [
{
"affiliation": "",
"forename": "E R",
"identifier": "",
"initials": "ER",
"lastname": "Rosenthal"
},
{
"affiliation": "",
"forename": "J M",
"identifier": "",
"initials": "JM",
"lastname": "Calvo"
}
] | 1987-04-05 | 3305961 | D000123:Acetyltransferases / Q000378:metabolism; D015500:Chloramphenicol O-Acetyltransferase; D005686:Galactokinase / Q000378:metabolism; D005809:Genes, Regulator; D007930:Leucine / Q000235:genetics*; D009876:Operon; D010957:Plasmids; D012367:RNA, Viral; D012234:Rho Factor / Q000235:genetics; D012486:Salmonella typhimurium / Q000201:enzymology / Q000235:genetics*; D013698:Templates, Genetic; D013728:Terminator Regions, Genetic; D014158:Transcription, Genetic | D016428:Journal Article; D013487:Research Support, U.S. Gov't, P.H.S. | D012367:RNA, Viral; D012234:Rho Factor; D000123:Acetyltransferases; D015500:Chloramphenicol O-Acetyltransferase; D005686:Galactokinase; D007930:Leucine | 10.1016/0022-2836(87)90673-5 | [] | false | eng | J Mol Biol | 2985088R | 0022-2836 | Netherlands | [
{
"agency": "PHS HHS",
"country": "United States",
"grant_acronym": "",
"grant_id": "14340"
}
] | "2024-08-13T08:46:10.209244Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||
Recognition and cleavage of the bacteriophage P1 packaging site (pac). I. Differential processing of the cleaved ends in vivo. | 194(3) | 453-68 | The packaging of bacteriophage P1 DNA into viral capsids is initiated at a specific DNA site called pac. During packaging, that site is cleaved and at least one of the resulting ends is encapsidated into a P1 virion. We show here that pac is located on a 620 base-pair fragment of P1 DNA (EcoRI-20). When that fragment is inserted into the chromosome of cells that are then infected with P1, packaging of host DNA into phage particles is initiated at pac and proceeds down the chromosome, unidirectionally, for about five to ten P1 "headfuls" (about 5 X 10(5) to 10 X 10(5) bases of DNA). Using an assay for pac cleavage that does not depend on DNA packaging, we have identified a set of five amber mutations that are mapped adjacent to pac, and that define a gene (gene 9) essential for pac cleavage. Amber mutations that are located in genes necessary for viral capsid formation (genes 4, 8 and 23), or in a gene necessary for "late" protein synthesis (gene 10), do not affect pac cleavage. The latter result suggests that the synthesis of the pac cleavage protein is not regulated co-ordinately with other phage morphogenesis proteins. The products of pac cleavage were analyzed using two different DNA substrates. In one case, a single copy of pac was placed in the chromosome of P1-sensitive cells. When those cells were infected with P1, we could detect the cleavage of as much as 70% of the pac-containing DNA. The pac end destined to be packaged in the virion was detected five to 20 times more efficiently than was the other end. Since this result is obtained whether or not the infecting P1 phage can encapsidate the cut pac site, the differential detection of pac ends is not simply a consequence of one end being packaged and the other not. In a second case, pac was located in cells on a small (5 X 10(3) bases) multicopy plasmid. When those cells were infected with P1, neither pac end was detected efficiently after P1 infection, unless the cells carried a recBCD- mutation. In recBCD- cells, the results with plasmid-pac substrates were similar to those obtained with chromosomally integrated pac substrates. We interpret these results to mean that, following pac cleavage, the end destined to be packaged is protected from cellular nucleases while the other end is degraded by the action of at least two nucleases, one of which is the product of the host recBCD gene.(ABSTRACT TRUNCATED AT 400 WORDS) | Journal of molecular biology | [
{
"affiliation": "",
"forename": "N",
"identifier": "",
"initials": "N",
"lastname": "Sternberg"
},
{
"affiliation": "",
"forename": "J",
"identifier": "",
"initials": "J",
"lastname": "Coulby"
}
] | 1987-04-05 | 3305962 | D001435:Bacteriophages / Q000235:genetics* / Q000502:physiology; D002213:Capsid / Q000378:metabolism*; D004261:DNA Replication; D004269:DNA, Bacterial; D004279:DNA, Viral / Q000378:metabolism*; D004926:Escherichia coli / Q000235:genetics; D007700:Kinetics; D008954:Models, Biological; D009154:Mutation; D010957:Plasmids; D014176:Protein Biosynthesis; D014161:Transduction, Genetic; D014779:Virus Replication | D016428:Journal Article | D004269:DNA, Bacterial; D004279:DNA, Viral | 10.1016/0022-2836(87)90674-7 | [] | false | eng | J Mol Biol | 2985088R | 0022-2836 | Netherlands | [] | "2024-08-13T08:46:10.210149Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||
The calcium antagonists. The Fleckenstein symposium. I.S.H.R. 12th congress. International Society for Heart Research. 9-13th February, 1986, Melbourne. Proceedings. | 19 Suppl 2() | 1-121 | Journal of molecular and cellular cardiology | [] | 1987-05 | 3305963 | D000818:Animals; D002121:Calcium Channel Blockers; D049673:History, 20th Century; D006801:Humans | D019215:Biography; D016456:Historical Article; D016428:Journal Article; D013485:Research Support, Non-U.S. Gov't | D002121:Calcium Channel Blockers | [] | false | eng | J Mol Cell Cardiol | 0262322 | 0022-2828 | England | [] | "2024-08-13T08:46:10.210816Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||||
Ca2+ in the heart. | 19 Suppl 2() | 1-18 | Ca research in the heart was historically surveyed. First, reference was made to the development of the concept involving Ca2+ in the contraction of skeletal muscle. This was followed by an overview of studies on Ca regulation in cardiac muscle. Emphasis was laid on the fact that the "Ca era" today originated from Ca research in muscle initiated by Ringer and expanded by Heilbrunn. | Journal of molecular and cellular cardiology | [
{
"affiliation": "",
"forename": "S",
"identifier": "",
"initials": "S",
"lastname": "Ebashi"
}
] | 1987-05 | 3305964 | D000818:Animals; D002118:Calcium / Q000502:physiology*; D006321:Heart / Q000502:physiology*; D049672:History, 19th Century; D049673:History, 20th Century; D009119:Muscle Contraction; D009132:Muscles / Q000502:physiology; D009200:Myocardial Contraction | D016456:Historical Article; D016428:Journal Article | D002118:Calcium | 10.1016/s0022-2828(87)80002-0 | [] | false | eng | J Mol Cell Cardiol | 0262322 | 0022-2828 | England | [] | "2024-08-13T08:46:10.211639Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||
Model experiments on anticalcinotic and antiarteriosclerotic arterial protection with calcium antagonists. | 19 Suppl 2() | 109-21 | Journal of molecular and cellular cardiology | [
{
"affiliation": "",
"forename": "A",
"identifier": "",
"initials": "A",
"lastname": "Fleckenstein"
}
] | 1987-05 | 3305965 | D000818:Animals; D002114:Calcinosis / Q000517:prevention & control*; D002118:Calcium / Q000378:metabolism; D002121:Calcium Channel Blockers / Q000627:therapeutic use*; D003324:Coronary Artery Disease / Q000517:prevention & control*; D003327:Coronary Disease / Q000517:prevention & control*; D004195:Disease Models, Animal; D006801:Humans; D006973:Hypertension / Q000517:prevention & control* | D016428:Journal Article; D016454:Review | D002121:Calcium Channel Blockers; D002118:Calcium | 10.1016/s0022-2828(87)80008-1 | [] | false | eng | J Mol Cell Cardiol | 0262322 | 0022-2828 | England | [] | "2024-08-13T08:46:10.212332Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||
The Automatic Implantable Cardioverter Defibrillator (AICD)--a clinical and technical review. | 11(3) | 97-102 | Journal of medical engineering & technology | [
{
"affiliation": "",
"forename": "S",
"identifier": "",
"initials": "S",
"lastname": "Nisam"
}
] | 1987 | 3305953 | D001145:Arrhythmias, Cardiac / Q000517:prevention & control; D001698:Biomedical Engineering; D004554:Electric Countershock / Q000009:adverse effects / Q000295:instrumentation*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019736:Prostheses and Implants | D016428:Journal Article; D016454:Review | 10.3109/03091908709018149 | [] | false | eng | J Med Eng Technol | 7702125 | 0309-1902 | England | [] | "2024-08-13T08:46:10.212838Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||||
Calcium channel blockers and early ischemic ventricular arrhythmias: electrophysiological versus anti-ischemic effects. | 19 Suppl 2() | 77-97 | Calcium antagonists are able to reduce the incidence of early ischemic arrhythmias when given as pretreatment in a variety of models of acute myocardial regional ischemia. Two possible modes of action are electrophysiologic and anti-ischemic. First, a direct electrophysiologic effect of the calcium antagonist agents on the inward calcium current could inhibit four calcium-dependent phenomena, each of which has been linked to the development of ischemic arrhythmias: the slow response, delayed afterdepolarizations (DADs) and calcium-dependent automaticity, enhanced membrane depolarization and conduction slowing. The special circumstances in which each of these could occur are delineated. An anti-ischemic effect of calcium antagonists must also be considered in some models, because of the negative inotropic, negative chronotropic and coronary and peripheral vasodilator properties. Thus far a specific role for the calcium current in early ischemic arrhythmias has only been shown in a few models and not tested in man. | Journal of molecular and cellular cardiology | [
{
"affiliation": "",
"forename": "W A",
"identifier": "",
"initials": "WA",
"lastname": "Coetzee"
},
{
"affiliation": "",
"forename": "S C",
"identifier": "",
"initials": "SC",
"lastname": "Dennis"
},
{
"affiliation": "",
"forename": "L H",
"identifier": "",
"initials": "LH",
"lastname": "Opie"
},
{
"affiliation": "",
"forename": "C A",
"identifier": "",
"initials": "CA",
"lastname": "Muller"
}
] | 1987-05 | 3305966 | D000818:Animals; D001145:Arrhythmias, Cardiac / Q000188:drug therapy*; D002118:Calcium / Q000378:metabolism*; D002121:Calcium Channel Blockers / Q000494:pharmacology / Q000627:therapeutic use*; D003327:Coronary Disease / Q000188:drug therapy*; D006352:Heart Ventricles / Q000503:physiopathology; D009206:Myocardium / Q000378:metabolism | D016428:Journal Article; D013485:Research Support, Non-U.S. Gov't; D016454:Review | D002121:Calcium Channel Blockers; D002118:Calcium | 10.1016/s0022-2828(87)80006-8 | [] | false | eng | J Mol Cell Cardiol | 0262322 | 0022-2828 | England | [] | "2024-08-13T08:46:10.214064Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||
Calcium antagonist drugs in the treatment of coronary spasm, effort angina and hypertension. | 19 Suppl 2() | 99-108 | The clinical use of calcium antagonist drugs in coronary artery disease preceded knowledge of the mechanism of their action. Basic research into their pharmacological actions and development of a wide range of compounds which block calcium entry into cells enabled clinicians to greatly expand the indications for their use. Thus the calcium antagonists were rediscovered and found to be potent anti-anginal drugs when used in adequate dosage for effort related angina. Knowledge of their potent relaxing action on vascular smooth muscle led to their use in coronary artery spasm. The exact trigger mechanism/s for spasm and the reason for enhanced vascular reactivity remain unclear, perhaps explaining the failure of specific antagonist therapy. Calcium antagonists acting nonspecifically inhibit both induced and spontaneous attacks of vasospastic angina. They may favourably influence the prognosis and are now drugs of first choice for this condition. The vasodilator action of these drugs has most recently been utilized to treat hypertension, with efficacy confirmed in many controlled trials. Unlike other vasodilators, the calcium antagonists reduce blood pressure without salt and water retention, and with mild or no stimulation of renin, aldosterone, or sympathetic nervous overactivity, and without postural effects. This spectrum of action makes them ideal therapeutic agents, and current guidelines are changing to include calcium antagonists as first or second line therapy. | Journal of molecular and cellular cardiology | [
{
"affiliation": "",
"forename": "S B",
"identifier": "",
"initials": "SB",
"lastname": "Freedman"
}
] | 1987-05 | 3305967 | D000787:Angina Pectoris / Q000188:drug therapy*; D002121:Calcium Channel Blockers / Q000627:therapeutic use*; D003329:Coronary Vasospasm / Q000188:drug therapy*; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D005082:Physical Exertion | D016428:Journal Article; D016454:Review | D002121:Calcium Channel Blockers | 10.1016/s0022-2828(87)80007-x | [] | false | eng | J Mol Cell Cardiol | 0262322 | 0022-2828 | England | [] | "2024-08-13T08:46:10.214732Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||
Poisons and poisoning: implication of physicians with man and nations. | 79(7) | 761-4 | Journal of the National Medical Association | [
{
"affiliation": "",
"forename": "H",
"identifier": "",
"initials": "H",
"lastname": "Bloch"
}
] | 1987-07 | 3305968 | D049668:History, 15th Century; D049690:History, Ancient; D049691:History, Medieval; D006801:Humans; D010820:Physicians / Q000266:history*; D011041:Poisoning / Q000266:history*; D011042:Poisons / Q000266:history* | D016456:Historical Article; D016428:Journal Article | D011042:Poisons | [
{
"citation": "Br Med J. 1947 Jan 25;1(4490):148-50",
"pmid": "20244692"
}
] | false | eng | J Natl Med Assoc | 7503090 | 0027-9684 | United States | [] | "2024-08-13T08:46:10.215486Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||||
Severe hepatotoxicity from Escherichia coli L-asparaginase. | 79(7) | 775, 779 | A 51-year-old black woman with diabetes mellitus developed severe hepatotoxicity after receiving high-dose L-asparaginase (Elspar) for acute lymphatic leukemia. Patients with diabetes should be given this drug cautiously. Glutaminase-free L-asparaginase from Vibrio succinogenes has been reported to be less hepatotoxic in mice; it might be a safer product for this group of patients. | Journal of the National Medical Association | [
{
"affiliation": "",
"forename": "R",
"identifier": "",
"initials": "R",
"lastname": "Jenkins"
},
{
"affiliation": "",
"forename": "E",
"identifier": "",
"initials": "E",
"lastname": "Perlin"
}
] | 1987-07 | 3305969 | D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001215:Asparaginase / Q000008:administration & dosage / Q000009:adverse effects*; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D003922:Diabetes Mellitus, Type 1 / Q000150:complications; D004926:Escherichia coli / Q000201:enzymology; D005260:Female; D006801:Humans; D007945:Leukemia, Lymphoid / Q000188:drug therapy*; D008875:Middle Aged | D002363:Case Reports; D016428:Journal Article | D001215:Asparaginase | [
{
"citation": "Cancer. 1970 Feb;25(2):253-78",
"pmid": "4905153"
},
{
"citation": "Cancer. 1971 Aug;28(2):361-4",
"pmid": "5109448"
},
{
"citation": "Cancer Res. 1983 Apr;43(4):1602-5",
"pmid": "6339039"
},
{
"citation": "Int J Cancer. 1982 Sep 15;30(3):343-7",
"pmid": "6752048"
},
{
"citation": "Anal Biochem. 1971 Nov;44(1):189-99",
"pmid": "4943713"
}
] | false | eng | J Natl Med Assoc | 7503090 | 0027-9684 | United States | [] | "2024-08-13T08:46:10.216512Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||
Transplant-derived astrocytes migrate into host lumbar and cervical spinal cord after implantation of E14 fetal cerebral cortex into adult thoracic spinal cord. | 17(4) | 391-403 | Fourteen-day gestation fetal cerebral cortex homografts were transplanted into the thoracic (T6) spinal cord between the left dorsal column and dorsal horn of adult host rats. The transplants were soaked in 2.0 micrograms/ml of the lectin Phaseolus vulgaris leucoagglutinin (PHAL) prior to implantation. Transplanted host spinal cords were utilized at 7, 14, and 24 d and at 1 and 2 months postimplantation. Paraffin-sectioned spinal cords were double labeled for PHAL and glial fibrillary acidic protein (GFAP) by using FITC- and RITC-conjugated secondary antisera, respectively. Montages of FITC- and RITC-positive cells were analyzed for cells containing both fluorescences. Double-labeled cells (PHAL-GFAP) were transplant-derived astrocytes. Transplant-derived astrocytes were observed to initiate migration in the white matter columns of the host at approximately 14 d after transplantation. Double-labeled astrocytes were observed in cervical and lumbar spinal cord of the host (ca. 3.5 cm away from the center of the transplant) at 2 months postoperative. These astrocytes migrated at approximately 0.76 mm a day (after a 14-d delay). At 2 months, transplant-derived astrocytes composed as much as 50% of the astrocytes in the white matter of the host 2.0 mm from the transplant. The migrated astrocytes were hypertrophied and appeared reactive. Astrocytes in spinal gray matter only migrate about 1.0 mm from the graft-host interface. Transplant-derived astrocytes can migrate the entire length of the spinal cord white matter. | Journal of neuroscience research | [
{
"affiliation": "",
"forename": "W J",
"identifier": "",
"initials": "WJ",
"lastname": "Goldberg"
},
{
"affiliation": "",
"forename": "J J",
"identifier": "",
"initials": "JJ",
"lastname": "Bernstein"
}
] | 1987 | 3305970 | D000818:Animals; D001253:Astrocytes / Q000032:analysis / Q000502:physiology*; D002465:Cell Movement; D002540:Cerebral Cortex / Q000166:cytology / Q000196:embryology / Q000637:transplantation*; D005333:Fetus; D005455:Fluorescent Antibody Technique; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis; D006085:Graft Survival; D006651:Histocytochemistry; D010835:Phytohemagglutinins; D051381:Rats; D011919:Rats, Inbred Strains; D013116:Spinal Cord / Q000502:physiology* / Q000601:surgery | D016428:Journal Article; D013486:Research Support, U.S. Gov't, Non-P.H.S. | D005904:Glial Fibrillary Acidic Protein; D010835:Phytohemagglutinins | 10.1002/jnr.490170410 | [] | false | eng | J Neurosci Res | 7600111 | 0360-4012 | United States | [] | "2024-08-13T08:46:10.217366Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||
Monoclonal antibodies to a brain dopamine binding protein: production, specificity, and immunohistochemistry. | 17(4) | 417-23 | A dopamine binding protein (DABP) has been purified from the rat brain synaptic membrane to homogeneity by affinity chromatography and gel electrophoresis. The monoclonal antibodies against the DABP were produced by the mouse-mouse hybridoma technique and characterized for their specificity to dopamine receptors by displacement of dopamine receptor binding. These monoclonal antibodies have been used to localize DABP in rat brain by immunohistochemistry. A specific linear structure of reaction product was seen in both caudate nucleus and cerebral cortex. This finding suggests that the DABP is present in the cerebral cortex and caudate nucleus as a membranous component of the neurons or their processes. | Journal of neuroscience research | [
{
"affiliation": "",
"forename": "L L",
"identifier": "",
"initials": "LL",
"lastname": "Hsu"
},
{
"affiliation": "",
"forename": "K",
"identifier": "",
"initials": "K",
"lastname": "Moroi"
},
{
"affiliation": "",
"forename": "B D",
"identifier": "",
"initials": "BD",
"lastname": "Lakchaura"
},
{
"affiliation": "",
"forename": "T",
"identifier": "",
"initials": "T",
"lastname": "Chan"
},
{
"affiliation": "",
"forename": "C T",
"identifier": "",
"initials": "CT",
"lastname": "Lin"
},
{
"affiliation": "",
"forename": "J Y",
"identifier": "",
"initials": "JY",
"lastname": "Wu"
}
] | 1987 | 3305971 | D000818:Animals; D000911:Antibodies, Monoclonal / Q000096:biosynthesis*; D000918:Antibody Specificity; D001201:Ascites / Q000276:immunology; D001923:Brain Chemistry; D002352:Carrier Proteins / Q000032:analysis / Q000276:immunology* / Q000302:isolation & purification; D002540:Cerebral Cortex / Q000378:metabolism; D003342:Corpus Striatum / Q000378:metabolism; D004298:Dopamine / Q000378:metabolism; D050483:Dopamine Plasma Membrane Transport Proteins; D006651:Histocytochemistry; D007124:Immunoenzyme Techniques; D008297:Male; D008562:Membrane Glycoproteins; D026901:Membrane Transport Proteins; D009419:Nerve Tissue Proteins; D051381:Rats; D011919:Rats, Inbred Strains; D011954:Receptors, Dopamine / Q000378:metabolism*; D013134:Spiperone / Q000378:metabolism; D013574:Synaptosomes / Q000378:metabolism | D016428:Journal Article; D013485:Research Support, Non-U.S. Gov't; D013487:Research Support, U.S. Gov't, P.H.S. | D000911:Antibodies, Monoclonal; D002352:Carrier Proteins; D050483:Dopamine Plasma Membrane Transport Proteins; D008562:Membrane Glycoproteins; D026901:Membrane Transport Proteins; D009419:Nerve Tissue Proteins; D011954:Receptors, Dopamine; D013134:Spiperone; D004298:Dopamine | 10.1002/jnr.490170413 | [] | false | eng | J Neurosci Res | 7600111 | 0360-4012 | United States | [
{
"agency": "NIGMS NIH HHS",
"country": "United States",
"grant_acronym": "GM",
"grant_id": "GM27589"
},
{
"agency": "PHS HHS",
"country": "United States",
"grant_acronym": "",
"grant_id": "NIS13224"
}
] | "2024-08-13T08:46:10.219696Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||
Carcinogenicity testing of chemicals. | 12(2) | 259-70 | The Journal of toxicological sciences | [
{
"affiliation": "",
"forename": "R",
"identifier": "",
"initials": "R",
"lastname": "Hess"
}
] | 1987-05 | 3305972 | D000818:Animals; D002273:Carcinogens / Q000145:classification; D004305:Dose-Response Relationship, Drug; D009152:Mutagenicity Tests / Q000379:methods*; D009374:Neoplasms, Experimental / Q000139:chemically induced* | D016428:Journal Article; D016454:Review | D002273:Carcinogens | 10.2131/jts.12.259 | [] | false | eng | J Toxicol Sci | 7805798 | 0388-1350 | Japan | [] | "2024-08-13T08:46:10.220431Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||
The present state of health in Africa. | 33 Suppl 1() | 6-8 | Journal of tropical pediatrics | [
{
"affiliation": "",
"forename": "M",
"identifier": "",
"initials": "M",
"lastname": "King"
}
] | 1987-06 | 3305973 | D000349:Africa; D003906:Developing Countries; D006262:Health; D006304:Health Status; D006801:Humans | D016428:Journal Article; D016454:Review | [] | false | eng | J Trop Pediatr | 8010948 | 0142-6338 | England | [] | "2024-08-13T08:46:10.221028Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||||
The prudent use of diagnostic ultrasound. | 6(8) | 415-6 | Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine | [
{
"affiliation": "",
"forename": "M C",
"identifier": "",
"initials": "MC",
"lastname": "Ziskin"
}
] | 1987-08 | 3305974 | D006801:Humans; D012306:Risk; D014463:Ultrasonography / Q000009:adverse effects* | D016421:Editorial | 10.7863/jum.1987.6.8.415 | [] | false | eng | J Ultrasound Med | 8211547 | 0278-4297 | England | [] | "2024-08-13T08:46:10.221592Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||||
Evaluation of fetal femur length for prediction of gestational age in a racially mixed obstetric population. | 6(8) | 417-9 | In a retrospective study, a group of 314 patients between 19 and 32 completed weeks' gestation were evaluated for differences in sonographic measurement of femur length vs. gestational age between the following racial categories: Hispanic, black, Oriental, and Caucasian. Selection criteria included known last menstrual period, singleton gestation, and a historic absence of maternal diabetes, hypertension, or renal disease or fetal anomalies. The gestational age against which the femur length was judged was determined from the last normal menstrual period, provided that this date differed by less than 2 weeks from age determined by fetal biparietal diameter and evaluation of the newborn. No statistically significant difference in femur length vs. gestational age was noted between the various racial categories. | Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine | [
{
"affiliation": "",
"forename": "K A",
"identifier": "",
"initials": "KA",
"lastname": "Ruvolo"
},
{
"affiliation": "",
"forename": "R A",
"identifier": "",
"initials": "RA",
"lastname": "Filly"
},
{
"affiliation": "",
"forename": "P W",
"identifier": "",
"initials": "PW",
"lastname": "Callen"
}
] | 1987-08 | 3305975 | D044466:Asian People; D044383:Black People; D005260:Female; D005269:Femur / Q000196:embryology*; D005865:Gestational Age; D006630:Hispanic or Latino; D006801:Humans; D011247:Pregnancy; D044469:Racial Groups; D014463:Ultrasonography; D014481:United States; D044465:White People | D003160:Comparative Study; D016428:Journal Article | 10.7863/jum.1987.6.8.417 | [] | false | eng | J Ultrasound Med | 8211547 | 0278-4297 | England | [] | "2024-08-13T08:46:10.222745Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||
Absorption of fetal intraperitoneal blood after intrauterine transfusion. | 6(8) | 421-3 | We reviewed the sonograms and medical records of all patients who underwent intrauterine transfusions between December 1981 and December 1984 in order to determine the time course for disappearance of the intraperitoneal blood. Seventy-two sonographic examinations were performed on 22 patients who underwent 51 intrauterine transfusions. Nonhydropic fetuses who received less than or equal to 50 cc of intraperitoneal blood exhibited no ultrasonic evidence of intraperitoneal fluid after 8 days. Nonhydropic fetuses receiving greater than 50 cc of intraperitoneal blood showed resolution of intraperitoneal fluid after 12 days. Hydropic fetuses, after intraperitoneal transfusion, all demonstrated persistence of intraperitoneal fluid. Intraperitoneal fluid was seen as long as 24 days after transfusion in hydropic fetuses. | Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine | [
{
"affiliation": "",
"forename": "B",
"identifier": "",
"initials": "B",
"lastname": "Hashimoto"
},
{
"affiliation": "",
"forename": "R A",
"identifier": "",
"initials": "RA",
"lastname": "Filly"
},
{
"affiliation": "",
"forename": "P W",
"identifier": "",
"initials": "PW",
"lastname": "Callen"
},
{
"affiliation": "",
"forename": "J T",
"identifier": "",
"initials": "JT",
"lastname": "Parer"
}
] | 1987-08 | 3305976 | D000042:Absorption; D001769:Blood / Q000378:metabolism*; D001805:Blood Transfusion, Intrauterine; D004487:Edema / Q000378:metabolism; D004899:Erythroblastosis, Fetal / Q000628:therapy; D005260:Female; D006801:Humans; D010537:Peritoneum / Q000378:metabolism*; D011247:Pregnancy; D013997:Time Factors; D014463:Ultrasonography | D016428:Journal Article | 10.7863/jum.1987.6.8.421 | [] | false | eng | J Ultrasound Med | 8211547 | 0278-4297 | England | [] | "2024-08-13T08:46:10.223701Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||
Healing of a muscle trauma. Correlation of sonographical and histological findings in an experimental study in rats. | 6(8) | 425-9 | Healing of a partially ruptured gastrocnemius muscle was studied in rats with sonographical and histological techniques. Ultrasonography was performed 1-21 days after injury using a 7.5-MHz linear scanner. Following ultrasonography, the injured muscles were examined histologically. The injured area and development of hematoma were visualized during the first 5 days after trauma with ultrasonographical and histological observations. Later, disorganization of regenerating muscle fibers appeared sonographically more clearly than the scar tissue area demonstrated histologically. The present study points out the accuracy of ultrasonography in the examination of a muscle trauma, especially during the early phases of healing. | Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine | [
{
"affiliation": "",
"forename": "M",
"identifier": "",
"initials": "M",
"lastname": "Lehto"
},
{
"affiliation": "",
"forename": "A",
"identifier": "",
"initials": "A",
"lastname": "Alanen"
}
] | 1987-08 | 3305977 | D000818:Animals; D008297:Male; D009132:Muscles / Q000293:injuries* / Q000473:pathology; D051381:Rats; D012421:Rupture; D014463:Ultrasonography; D014945:Wound Healing | D003160:Comparative Study; D016428:Journal Article | 10.7863/jum.1987.6.8.425 | [] | false | eng | J Ultrasound Med | 8211547 | 0278-4297 | England | [] | "2024-08-13T08:46:10.224579Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||
Significance of ultrasound measurements of the head of the breech fetus. | 6(8) | 437-9 | Ultrasound measurements of head shape and size in 451 fetuses presenting as a breech were compared to those obtained in 1,880 fetuses presenting as a cephalic between 15 and 40 weeks' gestation. No statistically significant differences were found for the biparietal diameter (BPD), head circumference (HC), or cephalic index (CI) measurements between the two groups in uncomplicated pregnancies. The mean values for the CI were found to be lower for breech presenting fetuses in complicated pregnancies, indicating a trend for these fetuses to have a more dolichocephalic head shape. | Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine | [
{
"affiliation": "",
"forename": "B",
"identifier": "",
"initials": "B",
"lastname": "Bader"
},
{
"affiliation": "",
"forename": "D",
"identifier": "",
"initials": "D",
"lastname": "Graham"
},
{
"affiliation": "",
"forename": "S",
"identifier": "",
"initials": "S",
"lastname": "Stinson"
}
] | 1987-08 | 3305978 | D001946:Breech Presentation; D002508:Cephalometry / Q000379:methods; D005260:Female; D006257:Head / Q000196:embryology*; D006801:Humans; D011247:Pregnancy; D014463:Ultrasonography | D016428:Journal Article | 10.7863/jum.1987.6.8.437 | [] | false | eng | J Ultrasound Med | 8211547 | 0278-4297 | England | [] | "2024-08-13T08:46:10.226729Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||
Sonography of the hand and foot in foreign body detection. | 6(8) | 441-7 | To evaluate the possibility that sonography might be effective in the clinical detection of foreign bodies in the soft tissues, we used high-resolution sonography to study 10 patients with suspected foreign bodies in the hand and foot. Using ultrasound, we detected foreign bodies (glass, metal wire) in the sole of the foot of two patients and glass in the hand of another. Seven patients were proved to be free of foreign bodies. In an experimental model to ascertain which types of foreign bodies could be detected by ultrasound, wood, glass, and metallic foreign bodies 2.5 cm in length that had been inserted into the flesh of a chicken breast were immediately identified by high-resolution sonography. Ultrasound also pinpointed the surface beneath which the foreign bodies lay and localized all precisely as to depth from the surface. While detection of a foreign body is important, precise localization is crucial to avoid miscalculation of surgery leading to increased tissue damage, blood loss, and an increased risk of complications. This initial study suggests that high-resolution sonography has applicability in both the detection and the precise localization of foreign bodies in the soft tissues, but the sensitivity and specificity of the procedure remains to be determined. | Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine | [
{
"affiliation": "",
"forename": "G A",
"identifier": "",
"initials": "GA",
"lastname": "Gooding"
},
{
"affiliation": "",
"forename": "T",
"identifier": "",
"initials": "T",
"lastname": "Hardiman"
},
{
"affiliation": "",
"forename": "M",
"identifier": "",
"initials": "M",
"lastname": "Sumers"
},
{
"affiliation": "",
"forename": "R",
"identifier": "",
"initials": "R",
"lastname": "Stess"
},
{
"affiliation": "",
"forename": "P",
"identifier": "",
"initials": "P",
"lastname": "Graf"
},
{
"affiliation": "",
"forename": "C",
"identifier": "",
"initials": "C",
"lastname": "Grunfeld"
}
] | 1987-08 | 3305979 | D000328:Adult; D000818:Animals; D002645:Chickens; D004195:Disease Models, Animal; D005528:Foot; D005547:Foreign Bodies / Q000175:diagnosis*; D005898:Glass; D006225:Hand; D006801:Humans; D008321:Mammary Glands, Animal; D008670:Metals; D014463:Ultrasonography; D014934:Wood | D016428:Journal Article | D008670:Metals | 10.7863/jum.1987.6.8.441 | [] | false | eng | J Ultrasound Med | 8211547 | 0278-4297 | England | [] | "2024-08-13T08:46:10.227631Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||
Sonographic diagnosis of lipoma of the corpus callosum. | 6(8) | 449-51 | Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine | [
{
"affiliation": "",
"forename": "R A",
"identifier": "",
"initials": "RA",
"lastname": "Christensen"
},
{
"affiliation": "",
"forename": "L E",
"identifier": "",
"initials": "LE",
"lastname": "Pinckney"
},
{
"affiliation": "",
"forename": "S",
"identifier": "",
"initials": "S",
"lastname": "Higgins"
},
{
"affiliation": "",
"forename": "K E",
"identifier": "",
"initials": "KE",
"lastname": "Miller"
}
] | 1987-08 | 3305980 | D001932:Brain Neoplasms / Q000151:congenital* / Q000175:diagnosis; D003337:Corpus Callosum; D006801:Humans; D007231:Infant, Newborn; D008067:Lipoma / Q000151:congenital* / Q000175:diagnosis; D008297:Male; D014463:Ultrasonography | D002363:Case Reports; D016428:Journal Article | 10.7863/jum.1987.6.8.449 | [] | false | eng | J Ultrasound Med | 8211547 | 0278-4297 | England | [] | "2024-08-13T08:46:10.228498Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||||
Posttransplant lymphoma. Sonographic characteristics of renal allograft involvement. | 6(8) | 453-6 | Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine | [
{
"affiliation": "",
"forename": "P D",
"identifier": "",
"initials": "PD",
"lastname": "Russ"
},
{
"affiliation": "",
"forename": "D E",
"identifier": "",
"initials": "DE",
"lastname": "Way"
},
{
"affiliation": "",
"forename": "D H",
"identifier": "",
"initials": "DH",
"lastname": "Pretorius"
},
{
"affiliation": "",
"forename": "M L",
"identifier": "",
"initials": "ML",
"lastname": "Manco-Johnson"
},
{
"affiliation": "",
"forename": "R",
"identifier": "",
"initials": "R",
"lastname": "Weil"
}
] | 1987-08 | 3305981 | D000328:Adult; D006801:Humans; D007668:Kidney / Q000473:pathology; D007680:Kidney Neoplasms / Q000175:diagnosis*; D016030:Kidney Transplantation; D008223:Lymphoma / Q000175:diagnosis / Q000209:etiology*; D008297:Male; D011183:Postoperative Complications / Q000175:diagnosis*; D014463:Ultrasonography | D002363:Case Reports; D016428:Journal Article | 10.7863/jum.1987.6.8.453 | [] | false | eng | J Ultrasound Med | 8211547 | 0278-4297 | England | [] | "2024-08-13T08:46:10.229501Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||||
Antenatal sonographic detection of benign dacrocystoceles (lacrimal duct cysts). | 6(8) | 461-5 | Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine | [
{
"affiliation": "",
"forename": "W K",
"identifier": "",
"initials": "WK",
"lastname": "Davis"
},
{
"affiliation": "",
"forename": "B S",
"identifier": "",
"initials": "BS",
"lastname": "Mahony"
},
{
"affiliation": "",
"forename": "B A",
"identifier": "",
"initials": "BA",
"lastname": "Carroll"
},
{
"affiliation": "",
"forename": "J D",
"identifier": "",
"initials": "JD",
"lastname": "Bowie"
}
] | 1987-08 | 3305983 | D000328:Adult; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis*; D006801:Humans; D007766:Lacrimal Apparatus Diseases / Q000175:diagnosis*; D011247:Pregnancy; D011296:Prenatal Diagnosis; D014463:Ultrasonography | D002363:Case Reports; D016428:Journal Article | 10.7863/jum.1987.6.8.461 | [] | false | eng | J Ultrasound Med | 8211547 | 0278-4297 | England | [] | "2024-08-13T08:46:10.230299Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||||
Sonographic findings of a spermatic cord lipoma. Case report and review of the literature. | 6(8) | 457-60 | Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine | [
{
"affiliation": "",
"forename": "W A",
"identifier": "",
"initials": "WA",
"lastname": "Kutchera"
},
{
"affiliation": "",
"forename": "E I",
"identifier": "",
"initials": "EI",
"lastname": "Bluth"
},
{
"affiliation": "",
"forename": "S L",
"identifier": "",
"initials": "SL",
"lastname": "Guice"
}
] | 1987-08 | 3305982 | D000328:Adult; D005834:Genital Neoplasms, Male / Q000175:diagnosis; D006801:Humans; D008067:Lipoma / Q000175:diagnosis*; D008297:Male; D013085:Spermatic Cord; D014463:Ultrasonography | D002363:Case Reports; D016428:Journal Article; D016454:Review | 10.7863/jum.1987.6.8.457 | [] | false | eng | J Ultrasound Med | 8211547 | 0278-4297 | England | [] | "2024-08-13T08:46:10.231100Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||||
Preoperative sonographic localization of a migrated transosseous stabilizing wire in the hand. | 6(8) | 471-3 | Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine | [
{
"affiliation": "",
"forename": "B D",
"identifier": "",
"initials": "BD",
"lastname": "Fornage"
}
] | 1987-08 | 3305984 | D001864:Bone Wires / Q000009:adverse effects*; D005260:Female; D005547:Foreign Bodies / Q000175:diagnosis*; D005548:Foreign-Body Migration / Q000175:diagnosis*; D006225:Hand; D006801:Humans; D008875:Middle Aged; D009984:Orthopedic Fixation Devices / Q000009:adverse effects*; D011300:Preoperative Care; D014463:Ultrasonography | D002363:Case Reports; D016428:Journal Article | 10.7863/jum.1987.6.8.471 | [] | false | eng | J Ultrasound Med | 8211547 | 0278-4297 | England | [] | "2024-08-13T08:46:10.231882Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||||
Asymptomatic cysts of the fetal choroid plexus in the second trimester. | 6(8) | 475-8 | Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine | [
{
"affiliation": "",
"forename": "B R",
"identifier": "",
"initials": "BR",
"lastname": "Benacerraf"
}
] | 1987-08 | 3305985 | D000328:Adult; D002831:Choroid Plexus; D003560:Cysts / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis*; D006801:Humans; D006849:Hydrocephalus / Q000175:diagnosis; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D011296:Prenatal Diagnosis; D014463:Ultrasonography | D002363:Case Reports; D016428:Journal Article | 10.7863/jum.1987.6.8.475 | [] | false | eng | J Ultrasound Med | 8211547 | 0278-4297 | England | [] | "2024-08-13T08:46:10.233675Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||||
Prenatal diagnosis of cystic CNS lesions in neonatal isoimmune thrombocytopenia. | 6(8) | 479-81 | Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine | [
{
"affiliation": "",
"forename": "R B",
"identifier": "",
"initials": "RB",
"lastname": "Lester"
},
{
"affiliation": "",
"forename": "J R",
"identifier": "",
"initials": "JR",
"lastname": "Sty"
}
] | 1987-08 | 3305986 | D000328:Adult; D001927:Brain Diseases / Q000175:diagnosis* / Q000276:immunology; D003560:Cysts / Q000175:diagnosis* / Q000276:immunology; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis* / Q000276:immunology; D006801:Humans; D007231:Infant, Newborn; D007519:Isoantigens / Q000276:immunology; D008297:Male; D011247:Pregnancy; D011296:Prenatal Diagnosis; D013921:Thrombocytopenia / Q000151:congenital* / Q000276:immunology; D014463:Ultrasonography | D002363:Case Reports; D016428:Journal Article | D007519:Isoantigens | 10.7863/jum.1987.6.8.479 | [] | false | eng | J Ultrasound Med | 8211547 | 0278-4297 | England | [] | "2024-08-13T08:46:10.234456Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||
Sequela of continuous ambulatory peritoneal dialysis (CAPD) mimicking primary gynecologic pathology. | 6(8) | 483-5 | Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine | [
{
"affiliation": "",
"forename": "L M",
"identifier": "",
"initials": "LM",
"lastname": "Vincent"
},
{
"affiliation": "",
"forename": "L A",
"identifier": "",
"initials": "LA",
"lastname": "Parker"
},
{
"affiliation": "",
"forename": "C A",
"identifier": "",
"initials": "CA",
"lastname": "Mittelstaedt"
}
] | 1987-08 | 3305987 | D000328:Adult; D001202:Ascitic Fluid; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D010386:Pelvic Neoplasms / Q000175:diagnosis*; D010531:Peritoneal Dialysis, Continuous Ambulatory / Q000009:adverse effects*; D014463:Ultrasonography | D002363:Case Reports; D016428:Journal Article | 10.7863/jum.1987.6.8.483 | [] | false | eng | J Ultrasound Med | 8211547 | 0278-4297 | England | [] | "2024-08-13T08:46:10.235200Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||||
Comparative value of ultrasonography, computerized tomography, angiography and excretory urography in the staging of renal cell carcinoma. | 138(3) | 482-4 | From 1982 to 1985, 225 patients with renal cell carcinoma were treated by nephrectomy. To evaluate the diagnostic significance of ultrasonography in predicting tumor stage the results of ultrasonography, computerized tomography, renal angiography and excretory urography were compared to the histopathological findings. Since local tumor extension has a considerable impact on the operation strategy evaluation of the T classification was of particular interest. All 4 diagnostic procedures were performed in 73 of the 225 patients. The T stage was determined correctly by ultrasonography in 77.8 per cent of the patients, while the tumor was not identifiable in only 0.6 per cent. Computerized tomography was almost as reliable as ultrasonography (the T stage was predicted correctly in 72.3 per cent of the examinations). In contrast, the tumor was staged correctly by angiography in only 57.2 per cent of the patients and by excretory urography in only 59.2 per cent. From these results ultrasonography appears to be an effective, noninvasive, inexpensive and safe procedure to evaluate the T stage of renal tumors. | The Journal of urology | [
{
"affiliation": "",
"forename": "H G",
"identifier": "",
"initials": "HG",
"lastname": "Frohmüller"
},
{
"affiliation": "",
"forename": "J W",
"identifier": "",
"initials": "JW",
"lastname": "Grups"
},
{
"affiliation": "",
"forename": "V",
"identifier": "",
"initials": "V",
"lastname": "Heller"
}
] | 1987-09 | 3305989 | D000792:Angiography; D002292:Carcinoma, Renal Cell / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D007668:Kidney / Q000473:pathology*; D007680:Kidney Neoplasms / Q000175:diagnosis / Q000473:pathology*; D009367:Neoplasm Staging; D011300:Preoperative Care; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography; D014567:Urography | D003160:Comparative Study; D016428:Journal Article | 10.1016/s0022-5347(17)43235-6 | [] | false | eng | J Urol | 0376374 | 0022-5347 | United States | [] | "2024-08-13T08:46:10.236162Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||
Use of fine needle aspiration for detection of stage A prostatic carcinoma before transurethral resection of the prostate: a clinical trial. | 138(3) | 551-3 | The incidence of stage A prostatic carcinoma is approximately 10 per cent. We performed a clinical trial to determine if pre-prostatectomy fine needle aspiration could detect reliably stage A prostatic carcinoma. In 102 men with clinically staged benign disease by digital examination we performed a 4-quadrant fine needle aspiration of the prostate before prostatectomy. The cytological diagnosis of the aspirate was compared to the pathological diagnosis obtained at prostatectomy in all patients. The incidence of stage A prostatic carcinoma in this group of patients was 18.6 per cent (19 of 102 men). Sufficient aspirate material for cytological diagnosis was obtained in 98 of 102 men (96 per cent), including 17 with a diagnosis of carcinoma. When adequate diagnostic material was obtained, fine needle aspiration detected all cases of clinical stage A2 prostatic carcinoma but it did not detect stage A1 prostatic carcinoma. There were no false positive diagnoses. We conclude that routine pre-prostatectomy fine needle aspiration of the prostate can be safe, cost-effective and clinically useful. | The Journal of urology | [
{
"affiliation": "",
"forename": "E H",
"identifier": "",
"initials": "EH",
"lastname": "Agatstein"
},
{
"affiliation": "",
"forename": "F J",
"identifier": "",
"initials": "FJ",
"lastname": "Hernandez"
},
{
"affiliation": "",
"forename": "L J",
"identifier": "",
"initials": "LJ",
"lastname": "Layfield"
},
{
"affiliation": "",
"forename": "R B",
"identifier": "",
"initials": "RB",
"lastname": "Smith"
},
{
"affiliation": "",
"forename": "J B",
"identifier": "",
"initials": "JB",
"lastname": "deKernion"
}
] | 1987-09 | 3305990 | D000368:Aged; D001707:Biopsy, Needle; D002277:Carcinoma / Q000473:pathology* / Q000601:surgery; D002986:Clinical Trials as Topic; D003365:Costs and Cost Analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011300:Preoperative Care; D011467:Prostate / Q000473:pathology*; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000473:pathology* / Q000601:surgery | D016430:Clinical Trial; D003160:Comparative Study; D018848:Controlled Clinical Trial; D016428:Journal Article; D013485:Research Support, Non-U.S. Gov't | 10.1016/s0022-5347(17)43254-x | [] | false | eng | J Urol | 0376374 | 0022-5347 | United States | [] | "2024-08-13T08:46:10.237179Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||
Antigenic relatedness between glycoproteins of human respiratory syncytial virus subgroups A and B: evaluation of the contributions of F and G glycoproteins to immunity. | 61(10) | 3163-6 | The degree of antigenic relatedness between human respiratory syncytial virus (RSV) subgroups A and B was estimated from antibody responses induced in cotton rats by respiratory tract infection with RSV. Glycoprotein-specific enzyme-linked immunosorbent assays of antibody responses induced by RSV infection demonstrated that the F glycoproteins of subgroups A and B were antigenically closely related (relatedness, R approximately 50%), whereas the G glycoproteins were only distantly related (R approximately 5%). Intermediate levels of antigenic relatedness (R approximately 25%) were seen in neutralizing antibodies from cotton rats infected with RSV of the two subgroups. Immunity against the F glycoprotein of subgroup A, induced by vaccinia-A2-F, conferred a high level of protection which was of comparable magnitude against challenge by RSV of either subgroup. In comparison, immunity against the G glycoprotein of subgroup A, induced by vaccinia-A2-G, conferred less complete, but significant, protection. Importantly, in vaccinia-A2-G-immunized animals, suppression of homologous challenge virus replication was significantly greater (13-fold) than that observed for the heterologous virus. | Journal of virology | [
{
"affiliation": "",
"forename": "P R",
"identifier": "",
"initials": "PR",
"lastname": "Johnson"
},
{
"affiliation": "",
"forename": "R A",
"identifier": "",
"initials": "RA",
"lastname": "Olmsted"
},
{
"affiliation": "",
"forename": "G A",
"identifier": "",
"initials": "GA",
"lastname": "Prince"
},
{
"affiliation": "",
"forename": "B R",
"identifier": "",
"initials": "BR",
"lastname": "Murphy"
},
{
"affiliation": "",
"forename": "D W",
"identifier": "",
"initials": "DW",
"lastname": "Alling"
},
{
"affiliation": "",
"forename": "E E",
"identifier": "",
"initials": "EE",
"lastname": "Walsh"
},
{
"affiliation": "",
"forename": "P L",
"identifier": "",
"initials": "PL",
"lastname": "Collins"
}
] | 1987-10 | 3305988 | D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis / Q000096:biosynthesis*; D000956:Antigens, Viral / Q000276:immunology*; D003411:Arvicolinae; D002460:Cell Line; D003429:Cross Reactions; D004797:Enzyme-Linked Immunosorbent Assay; D006023:Glycoproteins / Q000276:immunology*; D006801:Humans; D007114:Immunization; D009500:Neutralization Tests; D012136:Respiratory Syncytial Viruses / Q000235:genetics / Q000276:immunology*; D010253:Respirovirus Infections / Q000276:immunology*; D014616:Vaccinia virus / Q000235:genetics; D014764:Viral Proteins / Q000276:immunology | D016428:Journal Article | D000914:Antibodies, Viral; D000956:Antigens, Viral; D006023:Glycoproteins; D014764:Viral Proteins | 10.1128/JVI.61.10.3163-3166.1987 | [
{
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{
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] | false | eng | J Virol | 0113724 | 0022-538X | United States | [] | "2024-08-13T08:46:10.239784Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||
No-incision pubovaginal suspension for stress incontinence. | 138(3) | 568-70 | We describe a modified needle suspension for urinary incontinence that eliminates all incisions. The anterior vaginal wall is suspended from the rectus fascia with 2 heavy nonabsorbable monofilament mattress sutures. The sutures pass down through and back up through the full thickness of the vaginal wall, and are tied suprapubically to bury the knot into the fat in the suprapubic puncture site. The technique is based on our laboratory observation that in rats and guinea pigs monofilament mattress sutures that are tied under tension to include the outside abdominal skin will cut through the skin, and become internalized and accepted without any residual inflammation if the knot is buried initially. The simplified technique makes routine use of outpatient surgery and allows for the use of local anesthesia only in selected patients. At 2 1/2 years the continence rate in the first 38 patients exceeded 87 per cent. There were no failures among the last 14 patients after the technique was modified to include an extra full thickness pass of the mattress suture through the vaginal wall. There have been no significant complications. | The Journal of urology | [
{
"affiliation": "",
"forename": "R F",
"identifier": "",
"initials": "RF",
"lastname": "Gittes"
},
{
"affiliation": "",
"forename": "K R",
"identifier": "",
"initials": "KR",
"lastname": "Loughlin"
}
] | 1987-09 | 3305991 | D000328:Adult; D000071938:Fasciotomy; D005260:Female; D006801:Humans; D013536:Suture Techniques; D013537:Sutures; D014550:Urinary Incontinence, Stress / Q000601:surgery*; D014621:Vagina / Q000601:surgery* | D016428:Journal Article; D013485:Research Support, Non-U.S. Gov't | 10.1016/s0022-5347(17)43261-7 | [] | false | eng | J Urol | 0376374 | 0022-5347 | United States | [] | "2024-08-13T08:46:10.240759Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||
A modest proposal for the diagnosis and treatment of urinary incontinence in women. | 138(3) | 597-8 | The Journal of urology | [
{
"affiliation": "",
"forename": "J G",
"identifier": "",
"initials": "JG",
"lastname": "Blaivas"
}
] | 1987-09 | 3305992 | D005260:Female; D006801:Humans; D013536:Suture Techniques; D014521:Urethra / Q000601:surgery; D014550:Urinary Incontinence, Stress / Q000175:diagnosis* / Q000601:surgery; D014621:Vagina / Q000601:surgery | D016421:Editorial | 10.1016/s0022-5347(17)43269-1 | [] | false | eng | J Urol | 0376374 | 0022-5347 | United States | [] | "2024-08-13T08:46:10.241731Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||||
Barium granuloma: an unusual cause of unilateral ureteral obstruction. | 138(3) | 614-6 | A small amount of barium extravasated at the time of colonic surgery led to the development of a barium granuloma that caused unilateral ureteral obstruction. Although the barium was not detected on radiography or urography preoperatively, it was clearly visible at the time of ureteral exploration and ureterolysis. | The Journal of urology | [
{
"affiliation": "",
"forename": "J M",
"identifier": "",
"initials": "JM",
"lastname": "Walther"
},
{
"affiliation": "",
"forename": "N A",
"identifier": "",
"initials": "NA",
"lastname": "Romas"
},
{
"affiliation": "",
"forename": "F C",
"identifier": "",
"initials": "FC",
"lastname": "Lowe"
}
] | 1987-09 | 3305993 | D001466:Barium Sulfate / Q000009:adverse effects*; D005119:Extravasation of Diagnostic and Therapeutic Materials / Q000150:complications*; D005260:Female; D005549:Foreign-Body Reaction / Q000209:etiology*; D006099:Granuloma / Q000209:etiology*; D006801:Humans; D008875:Middle Aged; D014517:Ureteral Obstruction / Q000209:etiology* | D002363:Case Reports; D016428:Journal Article | D001466:Barium Sulfate | 10.1016/s0022-5347(17)43276-9 | [] | false | eng | J Urol | 0376374 | 0022-5347 | United States | [] | "2024-08-13T08:46:10.242507Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||
Unusual urological presentations of acquired immune deficiency syndrome: large cell lymphoma. | 138(3) | 627-9 | We describe 2 patients with unrecognized acquired immunodeficiency syndrome who presented with acute urological conditions. One patient had inapparent obstructive anuric renal failure and the other had a testicular mass. The etiology in each case was large cell lymphoma. Recognition of the acquired immunodeficiency syndrome by urologists requires an awareness of its many unusual presentations. | The Journal of urology | [
{
"affiliation": "",
"forename": "J L",
"identifier": "",
"initials": "JL",
"lastname": "Mohler"
},
{
"affiliation": "",
"forename": "J P",
"identifier": "",
"initials": "JP",
"lastname": "Jarow"
},
{
"affiliation": "",
"forename": "F F",
"identifier": "",
"initials": "FF",
"lastname": "Marshall"
}
] | 1987-09 | 3305994 | D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D058186:Acute Kidney Injury / Q000209:etiology*; D000328:Adult; D006716:Homosexuality; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000209:etiology*; D008297:Male; D013736:Testicular Neoplasms / Q000209:etiology* | D002363:Case Reports; D016428:Journal Article | 10.1016/s0022-5347(17)43281-2 | [] | false | eng | J Urol | 0376374 | 0022-5347 | United States | [] | "2024-08-13T08:46:10.243403Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||
Improved identification of renal arteries in patients with aortic aneurysms by means of high-resolution computed tomography. | 6(3) | 262-8 | Suprarenal extension of abdominal aortic aneurysms (AAAs) has been reported to be present in less than 10% of patients. Its preoperative demonstration is of value in planning the aneurysm repair; however, the most appropriate radiologic method of assessment remains controversial. Although many practitioners advocate angiography, recent advances in noninvasive techniques challenge this approach. To determine the optimal method of assessment, a retrospective study of CT, ultrasonography, and angiography was undertaken in a group of 101 patients with AAA. Conventional CT was used in all patients and high-resolution CT through the region of the renal vein was used in 45 of these patients. Ultrasonography was used in 27 patients and angiography in 23. Conventional CT detected the renal artery origins in 76% of the cases--results that improved to 98% when thin-section high-resolution CT was used. These improvements in CT make the delineation of the relationship of the renal arteries to the aortic aneurysms almost as accurate as angiography at approximately half the cost. Its accuracy, safety, and cost effectiveness make CT the modality of choice in the preoperative assessment of suprarenal aortic aneurysms. | Journal of vascular surgery | [
{
"affiliation": "",
"forename": "M N",
"identifier": "",
"initials": "MN",
"lastname": "Gomes"
},
{
"affiliation": "",
"forename": "P L",
"identifier": "",
"initials": "PL",
"lastname": "Choyke"
}
] | 1987-09 | 3305996 | D000792:Angiography; D001012:Aorta, Abdominal; D001014:Aortic Aneurysm / Q000175:diagnosis / Q000000981:diagnostic imaging*; D003365:Costs and Cost Analysis; D006801:Humans; D011300:Preoperative Care; D012077:Renal Artery / Q000000981:diagnostic imaging*; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography | D003160:Comparative Study; D016428:Journal Article | [] | false | eng | J Vasc Surg | 8407742 | 0741-5214 | United States | [] | "2024-08-13T08:46:10.245499Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||||
Selection of kidney recipients. | 258(10) | 1328-9 | JAMA | [] | 1987-09-11 | 3305997 | D035082:Federal Government; D033161:Government Regulation; D006650:Histocompatibility Testing; D018594:Human Body; D006801:Humans; D016030:Kidney Transplantation; D018579:Patient Selection; D009927:Tissue and Organ Procurement | D016422:Letter | American Society of Transplant Physicians; American Society of Transplant Surgeons; Health Care and Public Health; Montefiore Medical Center (Bronx, NY); National Organ Transplant Act; Professional Patient Relationship; United Network for Organ Sharing | [] | false | eng | 24272 | JAMA | 7501160 | 0098-7484 | United States | [] | "2024-08-13T08:46:10.247409Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||
Identification of "tumor-associated" nucleolar antigens in human urothelial cancer. | 138(3) | 636-9 | Nucleoli isolated from HeLa S3 cells were used to produce rabbit antisera capable of binding nucleoli of transitional cell carcinomas (TCCa) of the bladder. Cross-reactivity of the rabbit antiserum with normal nucleoli was reduced by absorption with fetal calf serum, normal human serum, and human placental nucleoli. This antinucleolar antiserum exhibited strong reactivity in immunoperoxidase assays performed on specimens of human bladder cancer. In frozen tissue sections of 24 patients with TCCa and eight individuals without tumor, nucleolar staining was observed in all malignant specimens, but was not observed in seven of the normal specimens. Cytologic examination of bladder washing specimens from 47 normal individuals showed absence of nucleolar staining in 43 (91%) of 47 normal specimens while 12 (86%) of 14 specimens from patients with TCCa were positive. These results suggest that there are antigens associated with the nucleoli of HeLa cells and transitional cell carcinomas which are generally absent (or in low concentration) in normal human urothelial cells, and that antisera to these antigens may be useful in the cytologic diagnosis of human transitional cell carcinoma. | The Journal of urology | [
{
"affiliation": "",
"forename": "D",
"identifier": "",
"initials": "D",
"lastname": "Yu"
},
{
"affiliation": "",
"forename": "T",
"identifier": "",
"initials": "T",
"lastname": "Pietro"
},
{
"affiliation": "",
"forename": "S",
"identifier": "",
"initials": "S",
"lastname": "Jurco"
},
{
"affiliation": "",
"forename": "P T",
"identifier": "",
"initials": "PT",
"lastname": "Scardino"
}
] | 1987-09 | 3305995 | D000818:Animals; D000951:Antigens, Neoplasm / Q000302:isolation & purification*; D002295:Carcinoma, Transitional Cell / Q000276:immunology*; D002466:Cell Nucleolus / Q000276:immunology; D003429:Cross Reactions; D006367:HeLa Cells; D006801:Humans; D007106:Immune Sera; D007124:Immunoenzyme Techniques; D011817:Rabbits; D001749:Urinary Bladder Neoplasms / Q000276:immunology* | D016428:Journal Article; D013485:Research Support, Non-U.S. Gov't; D013487:Research Support, U.S. Gov't, P.H.S. | D000951:Antigens, Neoplasm; D007106:Immune Sera | 10.1016/s0022-5347(17)43288-5 | [] | false | eng | J Urol | 0376374 | 0022-5347 | United States | [
{
"agency": "PHS HHS",
"country": "United States",
"grant_acronym": "",
"grant_id": "80-P-8"
}
] | "2024-08-13T08:46:10.249158Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||
The provision and financing of medical care for AIDS patients in US public and private teaching hospitals. | 258(10) | 1343-6 | The National Association of Public Hospitals and the Association of American Medical Colleges' Council of Teaching Hospitals conducted a detailed survey on hospital care to patients with acquired immunodeficiency syndrome (AIDS) in major US public and private teaching institutions in 1985. The 169 hospitals treating patients with AIDS that responded to the survey reported providing inpatient services to 5393 patients with AIDS. These patients accounted for 171,205 inpatient days and 8806 inpatient admissions, with an average length of stay of 19 days. The average costs and revenue for patients with AIDS per day were $635 and $482, respectively, with Medicaid representing the most frequent third-party payer. The average inpatient cost per patient per year was $20,320. Using Centers for Disease Control estimates of 18,720 patients diagnosed as having AIDS and alive during any part of 1985, we estimate that the total cost of inpatient care for patients with AIDS was $380 million for that year. We also found significant regional and ownership differences in source of payment for patients with AIDS and regional differences in revenues received for AIDS treatment. Results indicate that the costs of treating patients with AIDS will profoundly affect major public and private teaching institutions, but that public teaching hospitals in states with restrictive Medicaid programs will be most adversely affected. | JAMA | [
{
"affiliation": "",
"forename": "D P",
"identifier": "",
"initials": "DP",
"lastname": "Andrulis"
},
{
"affiliation": "",
"forename": "V S",
"identifier": "",
"initials": "VS",
"lastname": "Beers"
},
{
"affiliation": "",
"forename": "J D",
"identifier": "",
"initials": "JD",
"lastname": "Bentley"
},
{
"affiliation": "",
"forename": "L S",
"identifier": "",
"initials": "LS",
"lastname": "Gage"
}
] | 1987-09-11 | 3305998 | D000163:Acquired Immunodeficiency Syndrome / Q000191:economics*; D003365:Costs and Cost Analysis; D006779:Hospitals, Public / Q000191:economics*; D006784:Hospitals, Teaching / Q000191:economics*; D006801:Humans; D007350:Insurance, Hospitalization; D008484:Medicaid / Q000191:economics; D040841:Resource Allocation; D014481:United States | D016428:Journal Article; D013485:Research Support, Non-U.S. Gov't | Empirical Approach; Health Care and Public Health; Medicaid | [] | false | eng | 24250 | JAMA | 7501160 | 0098-7484 | United States | [] | "2024-08-13T08:46:10.250364Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||
In vivo diagnostic testing and immunotherapy for allergy. Report I, Part I, of the allergy panel. Council on Scientific Affairs. | 258(10) | 1363-7 | The diagnosis and treatment of allergic disease constitute a particularly difficult and complex field in medicine, a field that has been complicated further by the promulgation and the use of unproved procedures and/or the inappropriate use of proved procedures. This report is the first in a series of reports prepared by a multidisciplinary panel appointed by the Council on Scientific Affairs of the American Medical Association. It discusses the necessity for proper clinical trials to generate reproducible results under similar conditions to adequately prove the validity of various diagnostic and therapeutic procedures. In vivo immunologic tests have been shown to be reliable and valid diagnostic tools and include skin tests with standardized allergenic extracts by prick, puncture, and intradermal techniques, skin end-point titration, and patch testing for contact allergic dermatitis. Other clinically useful physiologic tests include the exercise tolerance test, methacholine and/or histamine inhalation challenge test, and other inhalation tests utilizing either nasal or bronchial delivery. Oral challenge testing has also been utilized and includes open, single-blind, or double-blind techniques, depending on the requirements of the patient being studied. The second article is a continuation of the first report, and describes other challenge tests and unproved procedures. The third report of this series evaluates in vitro tests for allergy. | JAMA | [] | 1987-09-11 | 3305999 | D001985:Bronchial Provocation Tests / Q000379:methods; D002986:Clinical Trials as Topic; D005512:Food Hypersensitivity / Q000175:diagnosis; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis* / Q000628:therapy; D007167:Immunotherapy; D016210:Methacholine Chloride; D008688:Methacholine Compounds; D005082:Physical Exertion; D012882:Skin Tests / Q000379:methods | D016430:Clinical Trial; D016428:Journal Article | D008688:Methacholine Compounds; D016210:Methacholine Chloride | [] | false | eng | JAMA | 7501160 | 0098-7484 | United States | [] | "2024-08-13T08:46:10.251358Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||
The differential diagnosis of depression. Relevance of positron emission tomography studies of cerebral glucose metabolism to the bipolar-unipolar dichotomy. | 258(10) | 1368-74 | JAMA | [
{
"affiliation": "",
"forename": "J M",
"identifier": "",
"initials": "JM",
"lastname": "Schwartz"
},
{
"affiliation": "",
"forename": "L R",
"identifier": "",
"initials": "LR",
"lastname": "Baxter"
},
{
"affiliation": "",
"forename": "J C",
"identifier": "",
"initials": "JC",
"lastname": "Mazziotta"
},
{
"affiliation": "",
"forename": "R H",
"identifier": "",
"initials": "RH",
"lastname": "Gerner"
},
{
"affiliation": "",
"forename": "M E",
"identifier": "",
"initials": "ME",
"lastname": "Phelps"
}
] | 1987-09-11 | 3306000 | D001714:Bipolar Disorder / Q000175:diagnosis* / Q000378:metabolism; D001921:Brain / Q000000981:diagnostic imaging / Q000378:metabolism*; D003847:Deoxyglucose / Q000031:analogs & derivatives; D003866:Depressive Disorder / Q000175:diagnosis* / Q000378:metabolism; D003937:Diagnosis, Differential; D019788:Fluorodeoxyglucose F18; D005947:Glucose / Q000378:metabolism*; D006801:Humans; D014055:Tomography, Emission-Computed | D016428:Journal Article; D013485:Research Support, Non-U.S. Gov't; D013486:Research Support, U.S. Gov't, Non-P.H.S.; D013487:Research Support, U.S. Gov't, P.H.S.; D016454:Review | D019788:Fluorodeoxyglucose F18; D003847:Deoxyglucose; D005947:Glucose | 10.1001/jama.258.10.1368 | [] | false | eng | JAMA | 7501160 | 0098-7484 | United States | [
{
"agency": "NINDS NIH HHS",
"country": "United States",
"grant_acronym": "NS",
"grant_id": "IK07-00588-04-NSPA"
},
{
"agency": "NIMH NIH HHS",
"country": "United States",
"grant_acronym": "MH",
"grant_id": "MH 37916-02"
}
] | "2024-08-13T08:46:10.252408Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||
Quest to improve marrow transplant success yields new approaches to graft-vs-host disease. | 258(11) | 1438-9 | JAMA | [
{
"affiliation": "",
"forename": "T F",
"identifier": "",
"initials": "TF",
"lastname": "Kirn"
}
] | 1987-09-18 | 3306001 | D016026:Bone Marrow Transplantation; D006086:Graft vs Host Disease / Q000188:drug therapy / Q000517:prevention & control*; D006801:Humans; D007938:Leukemia / Q000628:therapy; D013792:Thalidomide / Q000627:therapeutic use | D016433:News | D013792:Thalidomide | [] | false | eng | JAMA | 7501160 | 0098-7484 | United States | [] | "2024-08-13T08:46:10.254364Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||||
The first school of medicine in the country. | 258(11) | 1479 | JAMA | [
{
"affiliation": "",
"forename": "M S",
"identifier": "",
"initials": "MS",
"lastname": "Roberts"
}
] | 1987-09-18 | 3306002 | D049671:History, 18th Century; D010414:Pennsylvania; D012577:Schools, Medical / Q000266:history* | D016456:Historical Article; D016422:Letter | [] | false | eng | JAMA | 7501160 | 0098-7484 | United States | [] | "2024-08-13T08:46:10.255000Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||||
In vivo diagnostic testing and immunotherapy for allergy. Report I, Part II, of the Allergy Panel. Council on Scientific Affairs. | 258(11) | 1505-8 | The first article in this series discussed the importance of properly designed clinical trials to validate various diagnostic and therapeutic procedures and also described clinically accepted and proved tests. This article discusses other challenge tests and unproved procedures. The value of provocation-neutralization procedures has been controversial; two promising clinical models have been developed that may allow definitive trials of efficacy. Immunotherapy with allergenic extracts has been shown to be a safe and effective procedure in carefully selected patients treated with potent, well-standardized antigens administered in adequate dosage. It has been proposed that many nonspecific signs or symptoms could be caused by exposure to Candida albicans or low-dose environmental substances. The cause-and-effect relationships between exposure to C albicans or other environmental substances and the disorders that are alleged to be associated with them are, for the most part, unproved. | JAMA | [] | 1987-09-18 | 3306003 | D000485:Allergens; D001514:Bee Venoms / Q000276:immunology; D002176:Candida albicans / Q000276:immunology; D003888:Desensitization, Immunologic; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis / Q000628:therapy*; D009500:Neutralization Tests | D016428:Journal Article | D000485:Allergens; D001514:Bee Venoms | [] | false | eng | JAMA | 7501160 | 0098-7484 | United States | [] | "2024-08-13T08:46:10.255637Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||
Approval of zidovudine (AZT) for acquired immunodeficiency syndrome. A challenge to the medical and pharmaceutical communities. | 258(11) | 1517 | JAMA | [
{
"affiliation": "",
"forename": "I",
"identifier": "",
"initials": "I",
"lastname": "Brook"
}
] | 1987-09-18 | 3306004 | D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy*; D000998:Antiviral Agents / Q000009:adverse effects / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004363:Drug Utilization; D006801:Humans; D013936:Thymidine / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D014481:United States; D014486:United States Food and Drug Administration; D015215:Zidovudine | D016430:Clinical Trial; D016428:Journal Article | D000998:Antiviral Agents; D015215:Zidovudine; D013936:Thymidine | [] | false | eng | JAMA | 7501160 | 0098-7484 | United States | [] | "2024-08-13T08:46:10.256536Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||||
Dermatologic changes associated with interleukin 2 administration. | 258(12) | 1624-9 | We have prospectively evaluated the skin changes that occurred in ten patients who were undergoing immunotherapy with interleukin 2 (IL-2) and autologous lymphokine-activated killer cells to treat cancer. Serial skin biopsy specimens were obtained before therapy (baseline), during IL-2 administration, and during IL-2/lymphokine-activated killer cell infusion. All patients developed an eruption that was characterized by macular erythema, with burning and pruritus of the skin. It began after two or three days of IL-2 infusion and was usually localized to the head and neck; it occasionally became generalized (ie, erythroderma). The eruption resolved with desquamation within 48 to 72 hours after cessation of infusion of IL-2. Histologically, the changes were not specific. The only consistent immunohistological finding noted was the presence of DR+/Leu-4+ lymphoid cells surrounding blood vessels in the papillary dermis, with fewer of these cells in the epidermis. There was no difference between the clinical or histological features of the eruption that occurred with IL-2 alone and that which occurred with IL-2 and lymphokine-activated killer cell infusion, suggesting that the cutaneous effects were mediated by IL-2 alone. | JAMA | [
{
"affiliation": "",
"forename": "A A",
"identifier": "",
"initials": "AA",
"lastname": "Gaspari"
},
{
"affiliation": "",
"forename": "M T",
"identifier": "",
"initials": "MT",
"lastname": "Lotze"
},
{
"affiliation": "",
"forename": "S A",
"identifier": "",
"initials": "SA",
"lastname": "Rosenberg"
},
{
"affiliation": "",
"forename": "J B",
"identifier": "",
"initials": "JB",
"lastname": "Stern"
},
{
"affiliation": "",
"forename": "S I",
"identifier": "",
"initials": "SI",
"lastname": "Katz"
}
] | 1987-09-25 | 3306005 | D000328:Adult; D004890:Erythema / Q000209:etiology* / Q000473:pathology; D005455:Fluorescent Antibody Technique; D006801:Humans; D007167:Immunotherapy / Q000009:adverse effects; D007376:Interleukin-2 / Q000009:adverse effects* / Q000627:therapeutic use; D007694:Killer Cells, Natural / Q000276:immunology; D008222:Lymphokines / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000628:therapy; D011446:Prospective Studies | D016428:Journal Article | D007376:Interleukin-2; D008222:Lymphokines | [] | false | eng | JAMA | 7501160 | 0098-7484 | United States | [] | "2024-08-13T08:46:10.257804Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||
Screening for abdominal aortic aneurysms: the U-boat in the belly. | 258(13) | 1732 | JAMA | [
{
"affiliation": "",
"forename": "F",
"identifier": "",
"initials": "F",
"lastname": "Santiago"
}
] | 1987-10-02 | 3306006 | D001012:Aorta, Abdominal; D001014:Aortic Aneurysm / Q000175:diagnosis*; D006801:Humans; D008403:Mass Screening; D008875:Middle Aged; D014463:Ultrasonography | D016422:Letter | [] | false | eng | JAMA | 7501160 | 0098-7484 | United States | [] | "2024-08-13T08:46:10.258640Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||||
Chlorosis lives!--and slips through MeSH. | 258(9) | 1174-5 | JAMA | [] | 1987-09-04 | 3306008 | D000747:Anemia, Hypochromic / Q000209:etiology*; D005260:Female; D006725:Hookworm Infections / Q000150:complications*; D006801:Humans; D007256:Information Systems; D008523:MEDLARS / Q000458:organization & administration*; D014481:United States | D002363:Case Reports; D016422:Letter | [] | false | eng | JAMA | 7501160 | 0098-7484 | United States | [] | "2024-08-13T08:46:10.259301Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||||
Article brings censure recommendation. | 258(9) | 1137 | JAMA | [
{
"affiliation": "",
"forename": "C",
"identifier": "",
"initials": "C",
"lastname": "Marwick"
}
] | 1987-09-04 | 3306007 | D035843:Biomedical Research; D003415:Crime; D003625:Data Collection; D035082:Federal Government; D005607:Fraud; D049673:History, 20th Century; D009316:National Institutes of Health (U.S.); D010380:Peer Review; D011643:Publishing; D014481:United States | D019215:Biography; D016456:Historical Article; D016433:News | Biomedical and Behavioral Research; National Institutes of Health; University of Cincinnati | [] | false | eng | 24224 | JAMA | 7501160 | 0098-7484 | United States | [] | "2024-08-13T08:46:10.261066Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||
Diagnosis of human immunodeficiency virus infection in seronegative homosexuals presenting with an acute viral syndrome. | 258(9) | 1196-9 | Early diagnosis of acute human immunodeficiency virus (HIV) infection is difficult because patients may be seronegative for HIV at the time of presentation. We have used a serum HIV antigen (HIV-Ag) enzyme immunoassay (EIA) to diagnose acute HIV infection in four high-risk patients. The clinical syndrome in these four patients was characterized by fever (four), rash (three), myalgias-arthralgias (three), and pharyngitis (two). All patients had spontaneous resolution of their symptoms within eight to 12 days. Serum HIV antibody, as measured by a commercially available screening EIA and by Western blot analysis, was negative in all patients at time of presentation and all seroconverted on subsequent testing. Human immunodeficiency virus was isolated from two of two patients during the acute illness. Initial serum samples from all four patients were positive for HIV-Ag. Serum samples of three of four patients became negative for HIV-Ag and positive for HIV antibody. These data suggest that serum HIV-Ag detection by EIA may be useful in the diagnosis of the acute syndrome caused by HIV infection. | JAMA | [
{
"affiliation": "",
"forename": "H A",
"identifier": "",
"initials": "HA",
"lastname": "Kessler"
},
{
"affiliation": "",
"forename": "B",
"identifier": "",
"initials": "B",
"lastname": "Blaauw"
},
{
"affiliation": "",
"forename": "J",
"identifier": "",
"initials": "J",
"lastname": "Spear"
},
{
"affiliation": "",
"forename": "D A",
"identifier": "",
"initials": "DA",
"lastname": "Paul"
},
{
"affiliation": "",
"forename": "L A",
"identifier": "",
"initials": "LA",
"lastname": "Falk"
},
{
"affiliation": "",
"forename": "A",
"identifier": "",
"initials": "A",
"lastname": "Landay"
}
] | 1987-09-04 | 3306009 | D000163:Acquired Immunodeficiency Syndrome / Q000150:complications / Q000175:diagnosis*; D000208:Acute Disease; D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis; D000956:Antigens, Viral / Q000032:analysis; D006678:HIV / Q000276:immunology; D015483:HIV Antibodies; D015488:HIV Antigens; D006716:Homosexuality; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D014777:Virus Diseases / Q000209:etiology* | D002363:Case Reports; D016428:Journal Article | D000914:Antibodies, Viral; D000956:Antigens, Viral; D015483:HIV Antibodies; D015488:HIV Antigens | [] | false | eng | JAMA | 7501160 | 0098-7484 | United States | [] | "2024-08-13T08:46:10.262014Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||
Hypertension in patients on chronic hemodialysis: the role of the renin-angiotensin system. | 51(5) | 479-84 | The effects of volume-loading and removal on mean blood pressure were evaluated in patients with high blood pressure and on chronic hemodialysis. Simultaneous measurements of plasma renin activity, plasma angiotensin II and plasma norepinephrine were made. The patients were divided into two groups according to their levels of plasma renin activity. Group 1 (n = 10) had a basal plasma renin activity below 2.5 ng/ml/hr while the level in group 2 (n = 5) exceeded 2.5 ng/ml/hr. The mean blood pressure of the two groups was 105 +/- 5 mmHg and 107 +/- 4 mmHg, respectively. On the day of hemodialysis, saline loading (0.5 ml/kg/min for 20 min) was followed by routine hemodialysis. The mean blood pressure rose to 113 +/- 6 mmHg in group 1. However, the patients in group 2 did not respond to volume loading and hemodialysis. The plasma renin activity, plasma angiotensin II and plasma norepinephrine were not changed by volume loading in both group 1 and 2. Volume removal by hemodialysis caused a reduction in mean blood pressure in group 2 without alteration of vasoactive hormones. In group 1, the mean blood pressure was not reduced by hemodialysis, accompanied by increases in plasma renin activity, plasma angiotensin II, and plasma norepinephrine. In the high renin group, elevated circulating angiotensin II maintained a high blood pressure and in the low renin group, the renin-angiotensin system influenced the prevention of fall in blood pressure after hemodialysis. These results suggest that the renin-angiotensin system plays an important role in the regulation of blood pressure in relation to volume status regardless of whether the plasma renin activity is high or low. | Japanese circulation journal | [
{
"affiliation": "",
"forename": "Y",
"identifier": "",
"initials": "Y",
"lastname": "Igarashi"
},
{
"affiliation": "",
"forename": "H",
"identifier": "",
"initials": "H",
"lastname": "Suzuki"
},
{
"affiliation": "",
"forename": "T",
"identifier": "",
"initials": "T",
"lastname": "Imafuku"
},
{
"affiliation": "",
"forename": "I",
"identifier": "",
"initials": "I",
"lastname": "Saito"
},
{
"affiliation": "",
"forename": "T",
"identifier": "",
"initials": "T",
"lastname": "Saruta"
}
] | 1987-05 | 3306010 | D000328:Adult; D000804:Angiotensin II / Q000097:blood; D001794:Blood Pressure; D005260:Female; D006400:Hematocrit; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000503:physiopathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009638:Norepinephrine / Q000097:blood; D006435:Renal Dialysis; D012083:Renin / Q000097:blood; D012084:Renin-Angiotensin System; D012965:Sodium Chloride / Q000494:pharmacology; D013997:Time Factors | D016428:Journal Article | D000804:Angiotensin II; D012965:Sodium Chloride; D012083:Renin; D009638:Norepinephrine | 10.1253/jcj.51.479 | [] | false | eng | Jpn Circ J | 7806868 | 0047-1828 | Japan | [] | "2024-08-13T08:46:10.263210Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||
Effects of sodium intake on the captopril test for primary aldosteronism. | 28(3) | 357-65 | The validity of the captopril test for primary aldosteronism (PA) was tested in patients with surgically verified PA (n = 12) or essential hypertension (EHT, n = 20) with different levels of sodium intakes. The patients were scheduled on 7 days each of three regimes of the prepared diet containing 34, 120 and 340 mEq of sodium chloride per day, and the captopril test was repeated in each period. For the test, captopril (50 mg) was administered orally at 9:00 A.M. after 1 hour of rest in a supine position, and venous blood samples were obtained before and 90 min after drug administration. Plasma aldosterone concentration (PAC; ng/dl) and plasma renin activity (PRA; ng/ml/h) were measured by radioimmunoassay. Under the three different sodium intakes, a PAC/PRA ratio greater than 20 at 90 min after captopril administration was sufficiently sensitive (0.95, 19/20) and specific (0.92, 55/60) to identify PA. Similarly, PA was associated with a PAC above 15 ng/dl 90 min after captopril. There were no complaints associated with the antihypertensive effects of the drug even when patients were sodium-restricted. These results confirmed that the captopril test is safe and useful for screening out-patients for PA, independent of individual differences in sodium intake. | Japanese heart journal | [
{
"affiliation": "",
"forename": "S",
"identifier": "",
"initials": "S",
"lastname": "Naomi"
},
{
"affiliation": "",
"forename": "T",
"identifier": "",
"initials": "T",
"lastname": "Umeda"
},
{
"affiliation": "",
"forename": "T",
"identifier": "",
"initials": "T",
"lastname": "Iwaoka"
},
{
"affiliation": "",
"forename": "T",
"identifier": "",
"initials": "T",
"lastname": "Sato"
}
] | 1987-05 | 3306011 | D000328:Adult; D000450:Aldosterone / Q000097:blood; D001794:Blood Pressure; D002216:Captopril; D004032:Diet; D005260:Female; D006801:Humans; D006929:Hyperaldosteronism / Q000175:diagnosis* / Q000503:physiopathology; D006973:Hypertension / Q000175:diagnosis / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D012083:Renin / Q000097:blood; D012964:Sodium / Q000008:administration & dosage* / Q000378:metabolism; D013997:Time Factors | D003160:Comparative Study; D016428:Journal Article; D013485:Research Support, Non-U.S. Gov't | D000450:Aldosterone; D002216:Captopril; D012964:Sodium; D012083:Renin | 10.1536/ihj.28.357 | [] | false | eng | Jpn Heart J | 0401175 | 0021-4868 | Japan | [] | "2024-08-13T08:46:10.264328Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||
[Comparison of chemical and immunological methods in fecal occult blood testing]. | 33(9) | 1049-51 | Conventional occult blood testing using the chemical method has been compared with newly developed immunological testing methods; the Hemoccult slide II (HEM II) test has been widely accepted as a guaiac test but such recent tests as the Latex agglutination test (Latex) and the Enzyme Immunoassay method (EIA) have also come to be employed. Thirty colorectal cancer patients, 30 gastric cancer patients and 30 healthy persons were subjected the three above described tests during 3 consecutive days while under no restricted diet. False positive rates during this three-day testing period were 26.7% in HEM II, 93.3 in Late and 8.3% in EIA. Although the immunological testing method has the advantage of reducing the false positive rate without the need for a restricted diet it is time-consuming and expensive. Considering these results as well as our previous knowledge accrued from a mass survey, it is suggested that a new flow-chart may be found necessary, in which an initial screening is given by the chemical method and then followed by a secondary screening by the immunological method. This new flow-chart, if routinely employed, would greatly facilitate the mass screening of colorectal cancer. | Gan no rinsho. Japan journal of cancer clinics | [
{
"affiliation": "",
"forename": "N",
"identifier": "",
"initials": "N",
"lastname": "Kikkawa"
},
{
"affiliation": "",
"forename": "H",
"identifier": "",
"initials": "H",
"lastname": "Takeuchi"
},
{
"affiliation": "",
"forename": "T",
"identifier": "",
"initials": "T",
"lastname": "Kawahara"
},
{
"affiliation": "",
"forename": "M",
"identifier": "",
"initials": "M",
"lastname": "Okamoto"
},
{
"affiliation": "",
"forename": "S",
"identifier": "",
"initials": "S",
"lastname": "Funahashi"
},
{
"affiliation": "",
"forename": "A",
"identifier": "",
"initials": "A",
"lastname": "Yamamoto"
}
] | 1987-08 | 3306012 | D006454:Hemoglobins / Q000276:immunology; D006801:Humans; D007163:Immunosorbent Techniques; D007841:Latex Fixation Tests; D009780:Occult Blood | D003160:Comparative Study; D004740:English Abstract; D016428:Journal Article; D013485:Research Support, Non-U.S. Gov't | D006454:Hemoglobins | [] | false | jpn | Gan No Rinsho | 1257753 | 0021-4949 | Japan | [] | "2024-08-13T08:46:10.265068Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||
[Chronic neutrophilic leukemia]. | 28(4) | 505-12 | [Rinsho ketsueki] The Japanese journal of clinical hematology | [
{
"affiliation": "",
"forename": "A B",
"identifier": "",
"initials": "AB",
"lastname": "Miura"
},
{
"affiliation": "",
"forename": "T",
"identifier": "",
"initials": "T",
"lastname": "Takahashi"
},
{
"affiliation": "",
"forename": "T",
"identifier": "",
"initials": "T",
"lastname": "Nishinari"
}
] | 1987-04 | 3306014 | D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003843:Deoxycytidine Monophosphate / Q000008:administration & dosage; D003937:Diagnosis, Differential; D006801:Humans; D007951:Leukemia, Myeloid / Q000175:diagnosis* / Q000188:drug therapy; D009504:Neutrophils; D011379:Prognosis | D004740:English Abstract; D016428:Journal Article; D016454:Review | D003843:Deoxycytidine Monophosphate | [] | false | jpn | Rinsho Ketsueki | 2984782R | 0485-1439 | Japan | [] | "2024-08-13T08:46:10.266605Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||||
The functional significance of the carbohydrate moiety of plasma glycoproteins. | 28(4) | 482-95 | [Rinsho ketsueki] The Japanese journal of clinical hematology | [
{
"affiliation": "",
"forename": "W",
"identifier": "",
"initials": "W",
"lastname": "Bürgi"
}
] | 1987-04 | 3306013 | D001809:Blood Viscosity; D002241:Carbohydrates / Q000032:analysis; D003165:Complement System Proteins / Q000032:analysis; D006023:Glycoproteins / Q000097:blood* / Q000502:physiology; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D009844:Oligosaccharides / Q000032:analysis; D011134:Polysaccharides / Q000032:analysis; D014168:Transferrin / Q000502:physiology | D016428:Journal Article; D016454:Review | D002241:Carbohydrates; D006023:Glycoproteins; D007136:Immunoglobulins; D009844:Oligosaccharides; D011134:Polysaccharides; D014168:Transferrin; D003165:Complement System Proteins | [] | false | eng | Rinsho Ketsueki | 2984782R | 0485-1439 | Japan | [] | "2024-08-13T08:46:10.267050Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||||
[Non-steroidal anti-inflammatory drugs. Mechanism of action of non-steroidal anti-inflammatory drugs]. | 45(5) | 1084-92 | Nihon rinsho. Japanese journal of clinical medicine | [
{
"affiliation": "",
"forename": "M",
"identifier": "",
"initials": "M",
"lastname": "Katori"
}
] | 1987-05 | 3306015 | D000700:Analgesics; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D001095:Arachidonic Acids / Q000378:metabolism; D003864:Depression, Chemical; D006801:Humans; D011453:Prostaglandins / Q000096:biosynthesis / Q000502:physiology | D016428:Journal Article; D016454:Review | D000700:Analgesics; D000894:Anti-Inflammatory Agents, Non-Steroidal; D001095:Arachidonic Acids; D011453:Prostaglandins | [] | false | jpn | Nihon Rinsho | 0420546 | 0047-1852 | Japan | [] | "2024-08-13T08:46:10.267436Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||||
[Non-steroidal anti-inflammatory drugs. Suppression of biological response and non-steroidal anti-inflammatory drugs]. | 45(5) | 1093-101 | Nihon rinsho. Japanese journal of clinical medicine | [
{
"affiliation": "",
"forename": "M",
"identifier": "",
"initials": "M",
"lastname": "Nishikawa"
},
{
"affiliation": "",
"forename": "S",
"identifier": "",
"initials": "S",
"lastname": "Shirakawa"
},
{
"affiliation": "",
"forename": "H",
"identifier": "",
"initials": "H",
"lastname": "Hidaka"
}
] | 1987-05 | 3306016 | D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000378:metabolism / Q000494:pharmacology*; D001095:Arachidonic Acids / Q000378:metabolism*; D003864:Depression, Chemical; D006801:Humans; D007109:Immunity / Q000187:drug effects; D007668:Kidney / Q000378:metabolism; D011453:Prostaglandins / Q000096:biosynthesis* | D016428:Journal Article; D016454:Review | D000894:Anti-Inflammatory Agents, Non-Steroidal; D001095:Arachidonic Acids; D011453:Prostaglandins | [] | false | jpn | Nihon Rinsho | 0420546 | 0047-1852 | Japan | [] | "2024-08-13T08:46:10.268037Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||||
[Rheology of erythrocyte sedimentation]. | 45(5) | 1127-35 | Nihon rinsho. Japanese journal of clinical medicine | [
{
"affiliation": "",
"forename": "S",
"identifier": "",
"initials": "S",
"lastname": "Oka"
}
] | 1987-05 | 3306017 | D001799:Blood Sedimentation; D004903:Erythrocyte Aggregation; D004907:Erythrocyte Deformability; D006112:Gravitation; D006400:Hematocrit; D006801:Humans; D012212:Rheology | D016428:Journal Article; D016454:Review | [] | false | jpn | 87312254 | Nihon Rinsho | 0420546 | 0047-1852 | Japan | [] | "2024-08-13T08:46:10.268610Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||||
[Granuloma formed as a biological response]. | 45(5) | 1136-43 | Nihon rinsho. Japanese journal of clinical medicine | [
{
"affiliation": "",
"forename": "T",
"identifier": "",
"initials": "T",
"lastname": "Okabe"
}
] | 1987-05 | 3306018 | D002454:Cell Differentiation; D002455:Cell Division; D006099:Granuloma / Q000209:etiology*; D006801:Humans; D008222:Lymphokines / Q000502:physiology; D008262:Macrophage Activation; D008264:Macrophages / Q000166:cytology / Q000276:immunology*; D015846:Monokines; D011506:Proteins / Q000502:physiology; D013601:T-Lymphocytes / Q000276:immunology | D016428:Journal Article; D016454:Review | D008222:Lymphokines; D015846:Monokines; D011506:Proteins | [] | false | jpn | Nihon Rinsho | 0420546 | 0047-1852 | Japan | [] | "2024-08-13T08:46:10.269332Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||||
[Biological production of interleukin 1 induced by stress]. | 45(5) | 931-8 | Nihon rinsho. Japanese journal of clinical medicine | [
{
"affiliation": "",
"forename": "M",
"identifier": "",
"initials": "M",
"lastname": "Yoshinaga"
},
{
"affiliation": "",
"forename": "F",
"identifier": "",
"initials": "F",
"lastname": "Goto"
},
{
"affiliation": "",
"forename": "S",
"identifier": "",
"initials": "S",
"lastname": "Ohkahara"
}
] | 1987-05 | 3306019 | D000818:Animals; D007249:Inflammation / Q000276:immunology* / Q000378:metabolism; D007375:Interleukin-1 / Q000096:biosynthesis* / Q000502:physiology; D009504:Neutrophils / Q000378:metabolism; D013312:Stress, Physiological / Q000503:physiopathology* | D016428:Journal Article; D016454:Review | D007375:Interleukin-1 | [] | false | jpn | Nihon Rinsho | 0420546 | 0047-1852 | Japan | [] | "2024-08-13T08:46:10.270070Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||||
[Inflammation and production of monokines. Origin of interleukin 1]. | 45(5) | 954-60 | Nihon rinsho. Japanese journal of clinical medicine | [
{
"affiliation": "",
"forename": "Y",
"identifier": "",
"initials": "Y",
"lastname": "Ishida"
},
{
"affiliation": "",
"forename": "Y",
"identifier": "",
"initials": "Y",
"lastname": "Azuno"
},
{
"affiliation": "",
"forename": "T",
"identifier": "",
"initials": "T",
"lastname": "Kaneko"
}
] | 1987-05 | 3306020 | D000595:Amino Acid Sequence; D000818:Animals; D006801:Humans; D007375:Interleukin-1 / Q000096:biosynthesis* / Q000502:physiology; D007962:Leukocytes / Q000378:metabolism*; D008264:Macrophages / Q000378:metabolism* | D016428:Journal Article; D016454:Review | D007375:Interleukin-1 | [] | false | jpn | Nihon Rinsho | 0420546 | 0047-1852 | Japan | [] | "2024-08-13T08:46:10.271821Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||||
[Inflammation and production of monokines. Hyperthermia induced by interleukin 1, endogenous pyrogen]. | 45(5) | 961-8 | Nihon rinsho. Japanese journal of clinical medicine | [
{
"affiliation": "",
"forename": "N",
"identifier": "",
"initials": "N",
"lastname": "Murakami"
}
] | 1987-05 | 3306021 | D000818:Animals; D001833:Body Temperature Regulation; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D006801:Humans; D007375:Interleukin-1 / Q000502:physiology*; D011749:Pyrogens | D016428:Journal Article; D016454:Review | D007375:Interleukin-1; D011749:Pyrogens | [] | false | jpn | Nihon Rinsho | 0420546 | 0047-1852 | Japan | [] | "2024-08-13T08:46:10.272404Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||||
[Inflammation and production of monokines. Role of interleukin 1 and relations to prostaglandins]. | 45(5) | 969-77 | Nihon rinsho. Japanese journal of clinical medicine | [
{
"affiliation": "",
"forename": "A",
"identifier": "",
"initials": "A",
"lastname": "Hattori"
},
{
"affiliation": "",
"forename": "S",
"identifier": "",
"initials": "S",
"lastname": "Koyama"
},
{
"affiliation": "",
"forename": "Y",
"identifier": "",
"initials": "Y",
"lastname": "Nakamori"
},
{
"affiliation": "",
"forename": "A",
"identifier": "",
"initials": "A",
"lastname": "Shibata"
}
] | 1987-05 | 3306022 | D000818:Animals; D006410:Hematopoiesis; D006801:Humans; D007249:Inflammation; D007375:Interleukin-1 / Q000378:metabolism / Q000502:physiology*; D008264:Macrophages / Q000502:physiology; D011453:Prostaglandins / Q000378:metabolism* / Q000502:physiology; D013928:Thromboxane A2 / Q000378:metabolism | D016428:Journal Article; D016454:Review | D007375:Interleukin-1; D011453:Prostaglandins; D013928:Thromboxane A2 | [] | false | jpn | Nihon Rinsho | 0420546 | 0047-1852 | Japan | [] | "2024-08-13T08:46:10.273114Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||||
[Extra-hepatic effect of monokines and other substances. Interleukin 1 and immune system]. | 45(5) | 978-87 | Nihon rinsho. Japanese journal of clinical medicine | [
{
"affiliation": "",
"forename": "T",
"identifier": "",
"initials": "T",
"lastname": "Takahashi"
},
{
"affiliation": "",
"forename": "R",
"identifier": "",
"initials": "R",
"lastname": "Suzuki"
},
{
"affiliation": "",
"forename": "K",
"identifier": "",
"initials": "K",
"lastname": "Kumagai"
}
] | 1987-05 | 3306023 | D000818:Animals; D000917:Antibody Formation; D006801:Humans; D007109:Immunity; D007375:Interleukin-1 / Q000096:biosynthesis / Q000502:physiology*; D008214:Lymphocytes / Q000276:immunology; D008264:Macrophages / Q000378:metabolism; D015846:Monokines; D011506:Proteins / Q000502:physiology*; D013950:Thymus Gland / Q000276:immunology | D016428:Journal Article; D016454:Review | D007375:Interleukin-1; D015846:Monokines; D011506:Proteins | [] | false | jpn | Nihon Rinsho | 0420546 | 0047-1852 | Japan | [] | "2024-08-13T08:46:10.274054Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||||
[Extra-hepatic effect of monokines and other substances. Metabolic response to inflammation]. | 45(5) | 988-94 | Nihon rinsho. Japanese journal of clinical medicine | [
{
"affiliation": "",
"forename": "M",
"identifier": "",
"initials": "M",
"lastname": "Kawakami"
},
{
"affiliation": "",
"forename": "Y",
"identifier": "",
"initials": "Y",
"lastname": "Abe"
}
] | 1987-05 | 3306024 | D000596:Amino Acids / Q000378:metabolism; D000818:Animals; D050260:Carbohydrate Metabolism; D005934:Glucagon / Q000378:metabolism; D006801:Humans; D006854:Hydrocortisone / Q000378:metabolism; D007249:Inflammation / Q000378:metabolism*; D007328:Insulin / Q000378:metabolism; D050356:Lipid Metabolism; D015846:Monokines; D011506:Proteins / Q000502:physiology* | D016428:Journal Article; D016454:Review | D000596:Amino Acids; D007328:Insulin; D015846:Monokines; D011506:Proteins; D005934:Glucagon; D006854:Hydrocortisone | [] | false | jpn | Nihon Rinsho | 0420546 | 0047-1852 | Japan | [] | "2024-08-13T08:46:10.274922Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||||
[Renal transplantation]. | 45(6) | 1346-53 | Nihon rinsho. Japanese journal of clinical medicine | [
{
"affiliation": "",
"forename": "T",
"identifier": "",
"initials": "T",
"lastname": "Inou"
}
] | 1987-06 | 3306026 | D006801:Humans; D007564:Japan; D007676:Kidney Failure, Chronic / Q000628:therapy; D016030:Kidney Transplantation; D014019:Tissue Donors | D016428:Journal Article | [] | false | jpn | Nihon Rinsho | 0420546 | 0047-1852 | Japan | [] | "2024-08-13T08:46:10.275496Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||||
[Extra-hepatic effect of monokines and other substances. Brain, muscles, connective tissue and interleukin 1]. | 45(5) | 995-1001 | Nihon rinsho. Japanese journal of clinical medicine | [
{
"affiliation": "",
"forename": "K",
"identifier": "",
"initials": "K",
"lastname": "Shimokado"
},
{
"affiliation": "",
"forename": "F",
"identifier": "",
"initials": "F",
"lastname": "Numano"
}
] | 1987-05 | 3306025 | D000818:Animals; D001808:Blood Vessels / Q000378:metabolism; D001921:Brain / Q000378:metabolism; D002455:Cell Division / Q000187:drug effects; D003115:Colony-Stimulating Factors / Q000378:metabolism; D003238:Connective Tissue / Q000378:metabolism; D005347:Fibroblasts / Q000166:cytology; D006801:Humans; D007375:Interleukin-1 / Q000502:physiology*; D009124:Muscle Proteins / Q000378:metabolism; D011509:Proteoglycans / Q000378:metabolism; D011749:Pyrogens; D012890:Sleep / Q000187:drug effects | D016428:Journal Article; D016454:Review | D003115:Colony-Stimulating Factors; D007375:Interleukin-1; D009124:Muscle Proteins; D011509:Proteoglycans; D011749:Pyrogens | [] | false | jpn | Nihon Rinsho | 0420546 | 0047-1852 | Japan | [] | "2024-08-13T08:46:10.277543Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
||||||
[Legislation related to the management of kidney failure]. | 45(6) | 1361-71 | Nihon rinsho. Japanese journal of clinical medicine | [
{
"affiliation": "",
"forename": "T",
"identifier": "",
"initials": "T",
"lastname": "Kusakari"
}
] | 1987-06 | 3306027 | D006266:Health Education; D006801:Humans; D007564:Japan; D007676:Kidney Failure, Chronic / Q000601:surgery*; D016030:Kidney Transplantation; D007878:Legislation as Topic; D014015:Tissue Banks | D016428:Journal Article | [] | false | jpn | Nihon Rinsho | 0420546 | 0047-1852 | Japan | [] | "2024-08-13T08:46:10.278164Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||||
[Dementia due to cerebrovascular disorders in Japan]. | 45(6) | 1373-84 | Nihon rinsho. Japanese journal of clinical medicine | [
{
"affiliation": "",
"forename": "H",
"identifier": "",
"initials": "H",
"lastname": "Fukuyama"
},
{
"affiliation": "",
"forename": "M",
"identifier": "",
"initials": "M",
"lastname": "Kameyama"
}
] | 1987-06 | 3306028 | D000368:Aged; D002561:Cerebrovascular Disorders / Q000150:complications*; D003704:Dementia / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged | D016428:Journal Article; D016454:Review | [] | false | jpn | Nihon Rinsho | 0420546 | 0047-1852 | Japan | [] | "2024-08-13T08:46:10.278799Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||||
[Detection of oncogenes and its application to clinical medicine]. | 45(6) | 1385-94 | Nihon rinsho. Japanese journal of clinical medicine | [
{
"affiliation": "",
"forename": "H",
"identifier": "",
"initials": "H",
"lastname": "Hirai"
},
{
"affiliation": "",
"forename": "F",
"identifier": "",
"initials": "F",
"lastname": "Takaku"
}
] | 1987-06 | 3306029 | D000818:Animals; D002478:Cells, Cultured; D007938:Leukemia / Q000235:genetics; D009857:Oncogenes; D011289:Preleukemia / Q000235:genetics; D011379:Prognosis; D014178:Translocation, Genetic | D016428:Journal Article; D016454:Review | [] | false | jpn | Nihon Rinsho | 0420546 | 0047-1852 | Japan | [] | "2024-08-13T08:46:10.279364Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
|||||||
[The role of platelets in hemostasis and thrombus formation]. | Spec No 71() | 1-9 | Rinsho byori. The Japanese journal of clinical pathology | [
{
"affiliation": "",
"forename": "M",
"identifier": "",
"initials": "M",
"lastname": "Yamanaka"
}
] | 1987-06 | 3306031 | D001792:Blood Platelets / Q000502:physiology*; D006487:Hemostasis; D006801:Humans; D013927:Thrombosis / Q000209:etiology* | D016428:Journal Article; D016454:Review | [] | false | jpn | Rinsho Byori | 2984781R | 0047-1860 | Japan | [] | "2024-08-13T08:46:10.279861Z" | https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/pubmed24n0110.xml.gz |
Subsets and Splits